{"symbol":"VLDLR","synonyms":["CARMQ1","CHRMQ1","CAMRQ1","VLDL-R","VLDLRCH"],"name":"very low density lipoprotein receptor","description":"The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]","ncbiEntrezGeneId":7436,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7436","proteins":[{"symbol":"VLDLR_HUMAN","href":"/api/1.0/protein/VLDLR_HUMAN"}],"hgncRootFamilies":[{"name":"Low density lipoprotein receptors","href":"/api/1.0/gene_family/Low+density+lipoprotein+receptors"}]}