{"symbol":"VMP1","synonyms":["TANGO5","EPG3","TMEM49"],"name":"vacuole membrane protein 1","description":"This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016]","ncbiEntrezGeneId":81671,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/81671","proteins":[{"symbol":"VMP1_HUMAN","href":"/api/1.0/protein/VMP1_HUMAN"}],"hgncRootFamilies":[]}