{"symbol":"WDR5","synonyms":["CFAP89","SWD3","BIG-3"],"name":"WD repeat domain 5","description":"This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":11091,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11091","proteins":[{"symbol":"WDR5_HUMAN","href":"/api/1.0/protein/WDR5_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}