{"symbol":"WFDC3","synonyms":["DJ447F3.3","WAP14"],"name":"WAP four-disulfide core domain 3","description":"This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":140686,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/140686","proteins":[{"symbol":"WFDC3_HUMAN","href":"/api/1.0/protein/WFDC3_HUMAN"}],"hgncRootFamilies":[{"name":"WAP four-disulfide core domain containing (WFDC)","href":"/api/1.0/gene_family/WAP+four-disulfide+core+domain+containing+%28WFDC%29"}]}