{"symbol":"WFDC6","synonyms":["WAP6","HEL-S-295","C20ORF171","DJ461P17.11"],"name":"WAP four-disulfide core domain 6","description":"This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Read-through transcription exists between this gene and the upstream SPINLW1 (serine peptidase inhibitor-like, with Kunitz and WAP domains 1) gene. [provided by RefSeq, Nov 2010]","ncbiEntrezGeneId":140870,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/140870","proteins":[{"symbol":"WFDC6_HUMAN","href":"/api/1.0/protein/WFDC6_HUMAN"}],"hgncRootFamilies":[{"name":"WAP four-disulfide core domain containing (WFDC)","href":"/api/1.0/gene_family/WAP+four-disulfide+core+domain+containing+%28WFDC%29"}]}