{"symbol":"WIPI1","synonyms":["WIPI49","ATG18","ATG18A"],"name":"WD repeat domain, phosphoinositide interacting 1","description":"This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]","ncbiEntrezGeneId":55062,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55062","proteins":[{"symbol":"WIPI1_HUMAN","href":"/api/1.0/protein/WIPI1_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}