{"symbol":"WIPI2","synonyms":["ATG21","WIPI-2","ATG18B","CGI-50"],"name":"WD repeat domain, phosphoinositide interacting 2","description":"WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":26100,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26100","proteins":[{"symbol":"WIPI2_HUMAN","href":"/api/1.0/protein/WIPI2_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}