{"symbol":"XAGE3","synonyms":["CT12.3A","CT12.3B","XAGE-3","PP9012","GAGED4","PLAC6"],"name":"X antigen family, member 3","description":"This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5\u0027 UTR. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":170626,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/170626","proteins":[{"symbol":"XAGE3_HUMAN","href":"/api/1.0/protein/XAGE3_HUMAN"}],"hgncRootFamilies":[]}