{"symbol":"XPNPEP3","synonyms":["NPHPL1","APP3","ICP55"],"name":"X-prolyl aminopeptidase 3, mitochondrial","description":"The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":63929,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/63929","proteins":[{"symbol":"XPP3_HUMAN","href":"/api/1.0/protein/XPP3_HUMAN"}],"hgncRootFamilies":[{"name":"Aminopeptidases","href":"/api/1.0/gene_family/Aminopeptidases"}]}