{"symbol":"XPO1","synonyms":["EXP1","CRM1","emb"],"name":"exportin 1","description":"This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]","ncbiEntrezGeneId":7514,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7514","proteins":[{"symbol":"XPO1_HUMAN","href":"/api/1.0/protein/XPO1_HUMAN"}],"hgncRootFamilies":[{"name":"Exportins (XPO)","href":"/api/1.0/gene_family/Exportins+%28XPO%29"}]}