{"symbol":"XRCC6","synonyms":["TLAA","KU70","CTC75","CTCBF","G22P1","ML8"],"name":"X-ray repair complementing defective repair in Chinese hamster cells 6","description":"The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2547,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2547","proteins":[{"symbol":"XRCC6_HUMAN","href":"/api/1.0/protein/XRCC6_HUMAN"}],"hgncRootFamilies":[]}