{"symbol":"YAP1","synonyms":["COB1","YAP2","YKI","YAP","YAP65"],"name":"Yes-associated protein 1","description":"This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":10413,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10413","proteins":[{"symbol":"YAP1_HUMAN","href":"/api/1.0/protein/YAP1_HUMAN"}],"hgncRootFamilies":[]}