{"symbol":"YWHAQ","synonyms":["14-3-3","1C5"],"name":"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta","description":"This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5\u0027 UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10971,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10971","proteins":[{"symbol":"1433T_HUMAN","href":"/api/1.0/protein/1433T_HUMAN"}],"hgncRootFamilies":[]}