{"symbol":"ZBTB7B","synonyms":["C-KROX","ZFP67","HCKROX","THPOK","ZFP-67","ZNF857B","CKROX","ZBTB15"],"name":"zinc finger and BTB domain containing 7B","description":"This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]","ncbiEntrezGeneId":51043,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51043","proteins":[{"symbol":"ZBT7B_HUMAN","href":"/api/1.0/protein/ZBT7B_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"BTB (POZ) domain containing (BTBD)","href":"/api/1.0/gene_family/BTB+%28POZ%29+domain+containing+%28BTBD%29"}]}