{"symbol":"ZC3HC1","synonyms":["HSPC216","NIPA"],"name":"zinc finger, C3HC-type containing 1","description":"This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":51530,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51530","proteins":[{"symbol":"NIPA_HUMAN","href":"/api/1.0/protein/NIPA_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}