{"symbol":"ZCRB1","synonyms":["ZCCHC19","MADP-1","MADP1","SNRNP31","RBM36"],"name":"zinc finger CCHC-type and RNA binding motif 1","description":"Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5\u0027 splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":85437,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/85437","proteins":[{"symbol":"ZCRB1_HUMAN","href":"/api/1.0/protein/ZCRB1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"}]}