{"symbol":"ZEB1","synonyms":["DELTAEF1","BZP","PPCD3","ZFHX1A","FECD6","NIL2A","ZFHEP","TCF8","AREB6"],"name":"zinc finger E-box binding homeobox 1","description":"This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]","ncbiEntrezGeneId":6935,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6935","proteins":[{"symbol":"ZEB1_HUMAN","href":"/api/1.0/protein/ZEB1_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}