{"symbol":"ZEB2","synonyms":["HSPC082","SMADIP1","ZFHX1B"],"name":"zinc finger E-box binding homeobox 2","description":"The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]","ncbiEntrezGeneId":9839,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9839","proteins":[{"symbol":"ZEB2_HUMAN","href":"/api/1.0/protein/ZEB2_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}