{"symbol":"ZIC1","synonyms":["ZIC","CRS6","ZNF201"],"name":"Zic family member 1","description":"This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":7545,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7545","proteins":[{"symbol":"ZIC1_HUMAN","href":"/api/1.0/protein/ZIC1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}