{"symbol":"ZIC4","synonyms":[],"name":"Zic family member 4","description":"This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009]","ncbiEntrezGeneId":84107,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84107","proteins":[{"symbol":"ZIC4_HUMAN","href":"/api/1.0/protein/ZIC4_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}