{"symbol":"ZMIZ1","synonyms":["MIZ","TRAFIP10","RAI17","ZIMP10","HZIMP10"],"name":"zinc finger, MIZ-type containing 1","description":"This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]","ncbiEntrezGeneId":57178,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57178","proteins":[{"symbol":"ZMIZ1_HUMAN","href":"/api/1.0/protein/ZMIZ1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}