{"symbol":"ZNF426","synonyms":["K-RBP"],"name":"zinc finger protein 426","description":"Kaposi\u0027s sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]","ncbiEntrezGeneId":79088,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79088","proteins":[{"symbol":"ZN426_HUMAN","href":"/api/1.0/protein/ZN426_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}