{"symbol":"ZNF451","synonyms":["COASTER","DJ417I1.1"],"name":"zinc finger protein 451","description":"Enables SUMO ligase activity; transcription corepressor activity; and transcription regulator inhibitor activity. Involved in negative regulation of transcription initiation by RNA polymerase II; negative regulation of transforming growth factor beta receptor signaling pathway; and protein sumoylation. Located in PML body. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":26036,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26036","proteins":[{"symbol":"ZN451_HUMAN","href":"/api/1.0/protein/ZN451_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}