BioGPS Cell Line Gene Expression Profiles Dataset

Description mRNA expression profiles for the NCI-60 panel of cancer cell lines
Measurement gene expression by microarray
Association gene-cell line associations by differential expression of gene across cell lines
Category transcriptomics
Resource BioGPS
Citation(s)
Last Updated 2015 Apr 06
Stats
  1. 12628 genes
  2. 93 cell lines
  3. 172238 gene-cell line associations

Data Access

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Script

Visualizations

  • Attribute Similarity

  • Gene Attribute

  • Gene Similarity

cell line Gene Sets

93 sets of genes with high or low expression in each cell line relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.

Gene Set Description
MCF7 A immortal human breast-derived cell line cell that has the characteristics: Human cell line derived from breast adenocarcinoma. TKG0479 (Deposited from Tohoku Univ.).
T3M4 A immortal human cell line cell that has the characteristics: Pancreatic adenocarcinoma producing CEA. K-ras activated. Cell growth is slow.
U20S
HSG
HL60 Human acute myeloid leukemia established from the peripheral blood of a 35-year-old woman with acute myeloid leukemia (AML FAB M2) in 1976.
U118 Human neuronal glioblastoma (grade III) cell line.
GM1600
GM2313
PANC1
SF295
HCC2998
HCT116 Human colon colorectal carcinoma cell line from a male organism. Human colon carcinoma cell line; established from the primary colon carcinoma of an adult man.
IOSE80
MALME 3M
SKOV3
HEK 293T
RS11846
RPMI 8226
OVCAR3
CCRT CEM
OVCAR5
OVCAR4
OVCAR8
SAOS2 Human osteogenic sarcoma, established from the primary osteogenic sarcoma of an 11-year-old Caucasian woman in 1973.
SF268
HCT15
GM2493
HELA Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951. Later diagnosis changed to adenocarcinoma, first aneuploid, continuously cultured human cell line.
K562 Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970.
MOLT4
NCVADR RES
UACC257
huh-7 HuH-7 is a well differentiated hepatocyte derived cellular carcinoma cell line that was originally taken from a liver tumor in a 57-year-old Japanese male in 1982. The line was established by Nakabayshi, H. and Sato, J. HuH-7 is an immortal cell line of epithelial-like tumorigenic cells. It usually grow in 2D monolayers.
COLO205
U251 Human glioma cell line. Morphology: glial; Species: human; Tumor: glioma.
A361
MD MB231
HS578T
T24
UACC62
MDA MB435 Was originally considered to be a breast cancer cell line but has since been identified as a melanoma cell line.
SN12C Human renal cell carcinoma cell line.
SNB75 Human glioblastoma cell line.
HT29
DU145 A immortal human prostate gland-derived cell line cell that has the characteristics: Human cell line derived from brain metastasis of prostate carcinoma. TKG0604(Deposited from Tohoku Univ.).
SHSYSY+RA
HEK293 Established from a human primary embryonal kidney transformed by adenovirus type 5.
A172 A immortal human brain-derived cell line cell that has the characteristics: Human cell line derived from glioblastoma. TKG0183(Deposited from Tohoku Univ.).
A204
HEK 293 T-rex
RL7
HOP92 Non-small cell lung adenocarcinoma cell line.
IGROV1
LOX IMVI Human melanoma cell line.
NCI H226
RXF393 Renal cancer cell line.
TK10 TK-10 was derived from a specimen of primary RCC obtained following a left radical nephrectomy in a 43-year-old male on August 21, 1980.
HT1080
786
SHSYSY-RA
ACHN
ZR75_1
SKMEL28
UO31 Human renal cancer cell line.
U87
NCI H322M Human non-small cell lung cancer cell line.
SR
SNB19
M14 The human melanoma cell line M14 has been established from surgically removed melanoma metastases.
JURKAT Human T cell leukemia, established from the peripheral blood of a 14-year-old boy with acute lymphoblastic leukemia (ALL) at first relapse in 1976; often this cell line is called JM (JURKAT and JM are derived from the same patient and are sister clones), occasionally JM may be a subclone with somewhat divergent features.
DLD1 Human colon adenocarcinoma established from a colorectal adenocarcinoma.
SF539
A549 Human lung carcinoma established from an explanted lung tumor which was removed from a 58-year-old Caucasian man in 1972; cells were described to induce tumors in athymic mice and to synthesize lecithin.
astrocytes
LN18 Human brain, cerebrum; right temporal lobe, glioblastoma; glioma; grade IV cell line; established from a 65 years old white male.
EKVX Non-small cell lung adenocarcinoma cell line.
GM2345
SKMEL5 Human caucasian skin melanoma cell line; established from a 24 year old Caucasian female. Derived from: axillary node.
CAKI1
A498
KM12 Human colon carcinoma cell line.
NCI 460
U138 Human glioblastoma cell line; established from a 47 years old human male.
GM133
HEPG2 Human hepatocellular carcinoma, established from the tumor tissue of a 15-year-old argentine boy with hepatocellular carcinoma in 1975.
NCI H23
SKMEL2
ALVA31 Human primary prostate tumor cell line.
GM97
SW620
HOP62 Non-small cell lung adenocarcinoma cell line.
LNCAP Human prostate carcinoma, established from the left supraclavicular lymph node metastasis from a 50-year-old man with prostate carcinoma in 1977; cells were described to be androgen-sensitive.
ACC3