BioGPS Cell Line Gene Expression Profiles Dataset

Description mRNA expression profiles for the NCI-60 panel of cancer cell lines
Measurement gene expression by microarray
Association gene-cell line associations by differential expression of gene across cell lines
Category transcriptomics
Resource BioGPS
Citation(s)
Last Updated 2015 Apr 06
Stats
  1. 12628 genes
  2. 93 cell lines
  3. 172238 gene-cell line associations

Data Access

API
Script

Visualizations

  • Attribute Similarity

  • Gene Attribute

  • Gene Similarity

cell line Gene Sets

93 sets of genes with high or low expression in each cell line relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.

Gene Set Description
786
A172 A immortal human brain-derived cell line cell that has the characteristics: Human cell line derived from glioblastoma. TKG0183(Deposited from Tohoku Univ.).
A204
A361
A498
A549 Human lung carcinoma established from an explanted lung tumor which was removed from a 58-year-old Caucasian man in 1972; cells were described to induce tumors in athymic mice and to synthesize lecithin.
ACC3
ACHN
ALVA31 Human primary prostate tumor cell line.
astrocytes
CAKI1
CCRT CEM
COLO205
DLD1 Human colon adenocarcinoma established from a colorectal adenocarcinoma.
DU145 A immortal human prostate gland-derived cell line cell that has the characteristics: Human cell line derived from brain metastasis of prostate carcinoma. TKG0604(Deposited from Tohoku Univ.).
EKVX Non-small cell lung adenocarcinoma cell line.
GM133
GM1600
GM2313
GM2345
GM2493
GM97
HCC2998
HCT116 Human colon colorectal carcinoma cell line from a male organism. Human colon carcinoma cell line; established from the primary colon carcinoma of an adult man.
HCT15
HEK 293 T-rex
HEK 293T
HEK293 Established from a human primary embryonal kidney transformed by adenovirus type 5.
HELA Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951. Later diagnosis changed to adenocarcinoma, first aneuploid, continuously cultured human cell line.
HEPG2 Human hepatocellular carcinoma, established from the tumor tissue of a 15-year-old argentine boy with hepatocellular carcinoma in 1975.
HL60 Human acute myeloid leukemia established from the peripheral blood of a 35-year-old woman with acute myeloid leukemia (AML FAB M2) in 1976.
HOP62 Non-small cell lung adenocarcinoma cell line.
HOP92 Non-small cell lung adenocarcinoma cell line.
HS578T
HSG
HT1080
HT29
huh-7 HuH-7 is a well differentiated hepatocyte derived cellular carcinoma cell line that was originally taken from a liver tumor in a 57-year-old Japanese male in 1982. The line was established by Nakabayshi, H. and Sato, J. HuH-7 is an immortal cell line of epithelial-like tumorigenic cells. It usually grow in 2D monolayers.
IGROV1
IOSE80
JURKAT Human T cell leukemia, established from the peripheral blood of a 14-year-old boy with acute lymphoblastic leukemia (ALL) at first relapse in 1976; often this cell line is called JM (JURKAT and JM are derived from the same patient and are sister clones), occasionally JM may be a subclone with somewhat divergent features.
K562 Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970.
KM12 Human colon carcinoma cell line.
LN18 Human brain, cerebrum; right temporal lobe, glioblastoma; glioma; grade IV cell line; established from a 65 years old white male.
LNCAP Human prostate carcinoma, established from the left supraclavicular lymph node metastasis from a 50-year-old man with prostate carcinoma in 1977; cells were described to be androgen-sensitive.
LOX IMVI Human melanoma cell line.
M14 The human melanoma cell line M14 has been established from surgically removed melanoma metastases.
MALME 3M
MCF7 A immortal human breast-derived cell line cell that has the characteristics: Human cell line derived from breast adenocarcinoma. TKG0479 (Deposited from Tohoku Univ.).
MD MB231
MDA MB435 Was originally considered to be a breast cancer cell line but has since been identified as a melanoma cell line.
MOLT4
NCI 460
NCI H226
NCI H23
NCI H322M Human non-small cell lung cancer cell line.
NCVADR RES
OVCAR3
OVCAR4
OVCAR5
OVCAR8
PANC1
RL7
RPMI 8226
RS11846
RXF393 Renal cancer cell line.
SAOS2 Human osteogenic sarcoma, established from the primary osteogenic sarcoma of an 11-year-old Caucasian woman in 1973.
SF268
SF295
SF539
SHSYSY+RA
SHSYSY-RA
SKMEL2
SKMEL28
SKMEL5 Human caucasian skin melanoma cell line; established from a 24 year old Caucasian female. Derived from: axillary node.
SKOV3
SN12C Human renal cell carcinoma cell line.
SNB19
SNB75 Human glioblastoma cell line.
SR
SW620
T24
T3M4 A immortal human cell line cell that has the characteristics: Pancreatic adenocarcinoma producing CEA. K-ras activated. Cell growth is slow.
TK10 TK-10 was derived from a specimen of primary RCC obtained following a left radical nephrectomy in a 43-year-old male on August 21, 1980.
U118 Human neuronal glioblastoma (grade III) cell line.
U138 Human glioblastoma cell line; established from a 47 years old human male.
U20S
U251 Human glioma cell line. Morphology: glial; Species: human; Tumor: glioma.
U87
UACC257
UACC62
UO31 Human renal cancer cell line.
ZR75_1