BioGPS Mouse Cell Type and Tissue Gene Expression Profiles Dataset

Description mRNA expression profiles for mouse tissues and cell types
Measurement gene expression by microarray
Association gene-cell type or tissue associations by differential expression of gene across cell types and tissues
Category transcriptomics
Resource BioGPS
Citation(s)
Last Updated
Stats
  1. 15437 genes
  2. 74 cell type or tissues
  3. 170878 gene-cell type or tissue associations

Data Access

API
Script

Visualizations

  • Attribute Similarity

  • Dataset

  • Gene Similarity

cell type or tissue Gene Sets

74 sets of genes with high or low expression in each cell type or tissue relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.

Gene Set Description
adiposetissue Connective tissue in which fat is stored and which has the cells distended by droplets of fat.
adrenalgland Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine.
amygdala The one of the four basal ganglia in each cerebral hemisphere that is part of the limbic system and consists of an almond-shaped mass of gray matter in the anterior extremity of the temporal lobe.
b220.bcell
bladder A membranous sac in animals that serves as the receptacle of a liquid or contains gas.
blastocysts
bone The hard form of connective tissue that constitutes the majority of the skeleton of most vertebrates; it consists of an organic component (the cells and matrix) and an inorganic, or mineral, component; the matrix contains a framework of collagenous fibers and is impregnated with the mineral component, chiefly calcium phosphate (85 per cent) and calcium carbonate (10 per cent), which imparts the quality of rigidity to bone.
bonemarrow The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells.
brownfat A mammalian heat-producing tissue occurring especially in human newborns and in hibernators.
c2c12 A immortal mouse muscle cell line cell that has the characteristics: Said differentiate to myotubes, but need confirmation. Backup of ECA91031101.
cd4.Tcell
cd8.Tcell
cerebellum A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe.
cerebralcortex The surface layer of gray matter of the cerebrum that functions chiefly in coordination of sensory and motor information.
cortex Outermost layer of an organ[WP].
digits
dorsalrootganglion A ganglion on the dorsal root of each spinal nerve that is one of a series of ganglia lodging cell bodies of sensory neurons.
dorsalstriatum Those portions of the caudate nucleus and especially the putamen located generally superior to a plane representing the anterior commissure; also called the dorsal basal ganglia; may function in motor activities with cognitive origins.
embryoday10.5
embryoday6.5
embryoday7.5
embryoday8.5
embryoday9.5
embryonic stem feeder layer
embryonic stem no feeder
epidermis The outer epithelial layer of the external integument of the animal body that is derived from the embryonic epiblast; specifically: the outer nonsensitive and nonvascular layer of the skin of a vertebrate that overlies the dermis.
fertilizedegg
frontalcortex Front part of the brain, involved in planning, organizing, problem solving, selective attention, personality and a variety of higher cognitive functions including behavior and emotions.
heart 1: A hollow muscular organ of vertebrate animals that by its rhythmic contraction acts as a force pump maintaining the circulation of the blood. 2: A structure in an invertebrate animal functionally analogous to the vertebrate heart.
hippocampus A curved elongated ridge that extends over the floor of the descending horn of each lateral ventricle of the brain and consists of gray matter covered on the ventricular surface with white matter; The hippocampus is a part of the temporal lobe, which has a well established role in learning, memory and emotion.
hypothalamus The ventral part of the diencephalon that forms the floor and part of the lateral wall of the third ventricle. Anatomically, it includes the preoptic area, optic tract, optic chiasm, mammillary bodies, tuber cinereum, infundibulum, and neurohypophysis, but for physiological purposes the neurohypophysis is considered a distinct structure. The hypothalamus may be divided into five regions or areas (area hypothalamica rostralis, area hypothalamica dorsalis, area hypothalamica intermedia, area hypothalamica lateralis and area hypothalamica posterior) or into three longitudinal zones (periventricular zone, medial zone, and lateral zone). The hypothalamic nuclei constitute that part of the corticodiencephalic mechanism that activates, controls and integrates the peripheral autonomic mechanisms, endocrine activity, and many somatic functions, e.g., a general regulation of water balance, body temperature, sleep, and food intake, and the development of secondary sex characteristics. The hypothalamus secretes vasopressin and oxytocin, which are stored in the pituitary, as well as many releasing factors (hypophysiotropic hormones), by means of which it exerts control over functions of the adenohypophysis.
kidney 1: One of a pair of vertebrate organs situated in the body cavity near the spinal column that excrete waste products of metabolism, in humans are bean-shaped organs about 4 1/2 inches (11 1/2 centimeters) long lying behind the peritoneum in a mass of fatty tissue, and consist chiefly of nephrons by which urine is secreted, collected, and discharged into a main cavity whence it is conveyed by the ureter to the bladder. 2: Any of various excretory organs of invertebrate animals.
largeintestine The more terminal division of the vertebrate intestine that is wider and shorter than the small intestine, typically divided into cecum, colon, and rectum, and concerned especially with the resorption of water and the formation of feces.
liver 1: A large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood (as by converting sugars into glycogen which it stores up until required and by forming urea). 2: Any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes.
lung One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates.
lymphnode Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.
M-1 A immortal mouse cell line cell that has the characteristics: Differentiate to macrophage and granulocyte
macrophage Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kupffer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans giant cells.
mainolfactoryepithelium.MOE.
mammarygland.lact.
mast cells
neuro2a Mus musculus (mouse) brain neuroblastoma cell line. Clone Neuro-2a was established by R.J. Klebe and F.H. Ruddle from a spontaneous tumor of a strain A albino mouse.
nih 3T3
olfactorybulb A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes).
oocyte The immature reproductive cell prior to fertilization; it is derived from an oogonium, and is called a primary oocyte prior to completion of the first maturation division, and a secondary oocyte between the first and second maturation division.
osteoblasts
osteoclasts
ovary One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones.
pancreas A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon.
pituitary A small oval endocrine organ that is attached to the infundibulum of the brain, consists of an epithelial anterior lobe joined by an intermediate part to a posterior lobe of nervous origin, and produces various internal secretions directly or indirectly impinging on most basic body functions.
placenta The vascular organ in mammals except monotremes and marsupials that unites the fetus to the maternal uterus and mediates its metabolic exchanges through a more or less intimate association of uterine mucosal with chorionic and usually allantoic tissues; also: an analogous organ in another animal.
preoptic
prostate A firm partly muscular partly glandular body that is situated about the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
retina The sensory membrane that lines the eye, is composed of several layers including one containing the rods and cones, and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve.
salivarygland The glands of the oral cavity whose combined secretion constitutes the saliva.
septal organ
septum (resp epith)
skeletalmuscle A usually voluntary muscle made up of elongated, multinucleated, transversely striated muscle fibers, having principally bony attachments.
smallintestine The part of the intestine that lies between the stomach and colon, consists of duodenum, jejunum, and ileum, secretes digestive enzymes, and is the chief site of the absorption of digested nutrients. The proximal portion of the intestine.
snoutepidermis
spinalcordlower
spinalcordupper
spleen A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes.
stomach A dilatation of the alimentary canal of a vertebrate communicating anteriorly with the esophagus and posteriorly with the duodenum.
substantianigra The substantia nigra is located in the mesencephalon (mid brain) region of the brain. It is part of the basal ganglia.
testis A typically paired male reproductive gland that produces sperm and that in most mammals is contained within the scrotum at sexual maturity.
thymus A glandular structure of largely lymphoid tissue that functions especially in the development of the body's immune system, is present in the young of most vertebrates typically in the upper anterior chest or at the base of the neck, and tends to atrophy in the adult.
thyroid A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin.
tongueepidermis
trachea 1: The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi. It is kept patent by a series of about twenty transverse horseshoe-shaped cartilages. Called also windpipe. 2: One of a system of minute tubes ramifying throughout the body of a terrestrial arthropod and delivering air to the tissues. Called also tracheal tubule.
trigeminal
umbilicalcord A cord arising from the navel that connects the fetus with the placenta.
uterus An organ of the female mammal for containing and usually for nourishing the young during development previous to birth.
vomeralnasalorgan.VMO.