DGIdb Drug Targets 2026 Dataset

Description Sets of proteins targeted by drugs by data aggregation
Measurement association by data aggregation
Association protein-drug associations by data aggregation and curation
Category physical interactions
Resource Drug-Gene Interaction Database
Citation(s)
Last Updated 2026 Aug 13
Stats
  1. 4408 genes
  2. 19235 drugs
  3. 68271 gene-drug associations

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drug Gene Sets

19235 sets of interacting proteins for drugs from the DGIdb Drug Targets 2026 dataset.

Gene Set Description
ALPROSTADIL
COBALT
TECHNETIUM TC 99M SUCCIMER
THROMBIN ALFA
DOLUTEGRAVIR SODIUM
ESLICARBAZEPINE ACETATE
BARICITINIB
BMS-911172
COMPOUND 13 [PMID: 34333981]
COMPOUND 21B [PMID: 31136173]
COMPOUND 6 [PMID: 34333981]
FORAZAPADIN
PILAVAPADIN
ANTIDEPRESSANT AGENT
FLUOXETINE HYDROCHLORIDE
ISOPROTERENOL
THERAPEUTIC GLUCOCORTICOID
THERAPEUTIC MELATONIN
4-ACRYLOYLPHENOL
ALANINE
CPP-115
DIVALPROEX SODIUM
DP-VPA
P-HYDROXYBENZALDEHYDE
PYRIDOXAL PHOSPHATE ANHYDROUS
PYRUVIC ACID A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
TIAGABINE HYDROCHLORIDE
VALPROIC ACID A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
VIGABATRIN
ATORVASTATIN A dihydroxy monocarboxylic acid that is a member of the drug class known as statins, used primarily for lowering blood cholesterol and for preventing cardiovascular diseases.
BIHELICAL APOA-I MIMETIC PEPTIDE 5A
CLOPIDOGREL A thienopyridine that has formula C16H16ClNO2S.
CYCLOSPORINE
DAUNORUBICIN LIPOSOMAL
DOXORUBICIN HYDROCHLORIDE
FENOFIBRATE MICRONIZED
PRASUGREL
PRAVASTATIN SODIUM
PROBUCOL
ROSUVASTATIN
SIMVASTATIN A fatty acid ester comprising a dihydroxyheptanoic acid unit condensed into a lactone; a partially reduced naphthalene structure; and a 2,2-dimethylbutyric acyl substituent at C17. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.
FLUOROURACIL
IMATINIB
QUERCETIN-3'-O-PHOSPHATE
1,4-BENZOQUINONE
2',4'-DIHYDROXYCHALCONE
2'-HYDROXYCHALCONE A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 2'.
3,4-DIHYDROXYXANTHONE
ABEMACICLIB
ALISKIREN
ALPHA-TOCOPHEROL
AMISULPRIDE
AMLODIPINE BESYLATE
ANTHRACYCLINE ANTINEOPLASTIC ANTIBIOTIC
ANTIBIOTIC
ANTICONVULSANT AGENT
ANTIFUNGAL AGENT An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. Antifungal agents differ from industrial fungicides in that they defend against fungi present in human or animal tissues.
ANTIPARASITIC AGENT
ASPARAGINE
ATAZANAVIR
ATENOLOL An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.
ATORVASTATIN CALCIUM TRIHYDRATE
AUSTOCYSTIN D
AVATROMBOPAG
AZATHIOPRINE A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
AZITHROMYCIN A macrolide antibiotic useful for the treatment of bacterial infections.
BAFETINIB
BIOCHANIN A A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy groups at position 5 and a methoxy group at position 4'.
BIRICODAR
BISANTRENE
BOCEPREVIR
BRECANAVIR
BROMOCRIPTINE MESYLATE
BRYOSTATIN 1
CABAZITAXEL
CAMPTOTHECIN A pyranoindolizinoquinoline that has formula C20H16N2O4.
CAPSAICIN A capsaicinoid that has formula C18H27NO3.
CARBOPLATIN A platinum coordination entity with cis square-planar geometry in which platinum(II) is coordinated to two ammonia ligands and a bidentate cyclobutane-1,1-dicarboxylate ligand.
CELIPROLOL
CERITINIB A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonylamino)phenyl substituents. Used for the treatment of ALK-positive metastatic non-small cell lung cancer.
CHEMBL:CHEMBL203365
CHEMBL:CHEMBL217425
CHEMBL:CHEMBL270688
CHEMBL:CHEMBL306786
CHEMBL:CHEMBL408422
CHEMBL:CHEMBL410907
CHEMBL:CHEMBL444075
CHEMBL:CHEMBL533293
CHEMBL:CHEMBL595816
CHLORPROMAZINE A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
CLARITHROMYCIN The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.
CLOMIPRAMINE A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
CODEINE ANHYDROUS
COLCHICINE An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.
COMPOUND 14 [PMID: 30925062]
CRIZOTINIB
CURCUMIN A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
DAPTOMYCIN
DASATINIB ANHYDROUS
DAUNORUBICIN HYDROCHLORIDE
DEFEROXAMINE
DELAVIRDINE
DENDROAMIDE A
DEXTROMETHORPHAN HYDROBROMIDE
DIAZEPAM A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
DIGOXIN Digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.
DIHYDRO-12-HYDROXY-2,2-DIMETHYL-2H,6H-PYRANO[3,2-B]XANTHEN-6-ONE
DIMETHYL SULFOXIDE A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
DOMPERIDONE
DOXYCYCLINE ANHYDROUS
DRONABINOL
EFAVIRENZ
ELACRIDAR
ENCEQUIDAR
EPIPODOPHYLLOTOXIN COMPOUND
EPIRUBICIN HYDROCHLORIDE
EPOTHILONE D An epothilone that has formula C27H41NO5S.
ERLOTINIB
ERYTHROMYCIN Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus).
ESOMEPRAZOLE SODIUM
ETRAVIRINE
EZETIMIBE A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer).
FEXOFENADINE HYDROCHLORIDE
FLAVOKAWAIN A
FLUVASTATIN
FLUVOXAMINE A 5-methoxyvalerophenone O-(2-aminoethyl)oxime that has formula C15H21F3N2O2.
FOLATE ANTAGONIST
FOLIC ACID An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
GABAPENTIN
GARLIC
GEFITINIB
GEMTUZUMAB OZOGAMICIN
GINKGO
GREEN TEA EXTRACT
HETEROCODEINE
HISTONE DEACETYLASE INHIBITOR
HYDROCHLOROTHIAZIDE
HYDROCORTISONE BUTYRATE
HYDROGEN PEROXIDE An inorganic peroxide that has formula H2O2.
IBUPROFEN, SODIUM SALT
IDARUBICIN An anthracycline antibiotic that has formula C26H27NO9.
IFOSFAMIDE The simplest member of the class of ifosfamides that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by 2-chloroethyl groups on both the nitrogen atoms respectively. It is a nitrogen mustard alkylating agent used in the treatment of advanced breast cancer.
IGURATIMOD
ITRACONAZOLE A dioxolane that has formula C35H38Cl2N8O4.
IVERMECTIN A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice.
LANIQUIDAR
LANSOPRAZOLE A sulfoxide that has formula C16H14F3N3O2S.
LENOGRASTIM
LEVOFLOXACIN ANHYDROUS
LIOTHYRONINE
LITHIUM CATION
LONAFARNIB
LOPINAVIR
LOVASTATIN A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as a antilipemic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).
MARIJUANA
MDR MODULATOR CBT-1
MEGESTROL ACETATE A steroid ester that has formula C24H32O4.
METHADONE HYDROCHLORIDE
METHYLPHENIDATE A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
METHYLPREDNISOLONE
METOCHALCONE
MICONAZOLE NITRATE
MILTEFOSINE A phospholipid that is the hexadecyl monoester of phosphocholine.
MILTIRONE
MITOXANTRONE A hydroxyanthraquinone that has formula C22H28N4O6.
MODAFINIL
MURUCOIDIN V
N-DESMETHYLCLOZAPINE
NABIXIMOLS
NAPROXEN SODIUM
NEFAZODONE A triazole that has formula C25H32ClN5O2.
NELFINAVIR
NEVIRAPINE
NICOTINE POLACRILEX
NIFEDIPINE A dihydropyridine that has formula C17H18N2O6.
NIMODIPINE A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
OMEPRAZOLE A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
ONDANSETRON HYDROCHLORIDE
OSIMERTINIB
OXCARBAZEPINE A dibenzoazepine derivative, having a carbamoyl group at the ring nitrogen, substituted with an oxo group at C-4 of the azepeine ring which is also hydrogenated at C-4 and C-5. It is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy.
PACLITAXEL PROTEIN-BOUND
PALBOCICLIB
PALIPERIDONE
PAREGORIC
PEGINTERFERON ALFA-2A
PEGYLATED LIPOSOMAL DOXORUBICIN HYDROCHLORIDE
PERVILLEINE B
PERVILLEINE C
PERVILLEINE D
PERVILLEINE F
PHENOBARBITAL A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
PHENOTHIAZINE
PLATINUM A nickel group element atom that has formula Pt.
POSACONAZOLE
PREDNISONE A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
PROBENECID
PROPRANOLOL HYDROCHLORIDE
PROTON PUMP INHIBITOR
PURGIN II
PYRAZINAMIDE
QUINIDINE A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy.
RANITIDINE HYDROCHLORIDE
RANOLAZINE
RASAGILINE
RECOMBINANT INTERLEUKIN-3
RECOMBINANT INTERLEUKIN-6
RESERPINE An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
RIBOCICLIB
RIFAMPIN
RIFAPENTINE
RITONAVIR A L-valine derivative in which the alpha-nitrogen of L-valinamide is substituted with a methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl group and the amide nitrogen by a (2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. An antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir.
RITUXIMAB
RO 31-8220 An imidothiocarbamic ester that has formula C25H23N5O2S.
ROCURONIUM A 5alpha-androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents.
ROMIDEPSIN
SCUTELLARIN The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.
SILIBININ
SIROLIMUS
SORAFENIB
SPIRONOLACTONE A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
TANGERETIN A pentamethoxyflavone flavone with methoxy groups at positions 4', 5, 6 , 7 and 8.
TARIQUIDAR
TAXOL C
TENOFOVIR ALAFENAMIDE
TERFENADINE
TESMILIFENE
TICAGRELOR
TOPIRAMATE A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.
TRABECTEDIN A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer.
TRASTUZUMAB
TRICHOSTATIN A A trichostatin that has formula C17H22N2O3.
TRIMETREXATE
VALSPODAR
VEMURAFENIB
VENETOCLAX
VERAPAMIL A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
VINBLASTINE
VINCA ALKALOID COMPOUND
VINCRISTINE A vinca alkaloid that has formula C46H56N4O10.
VINDESINE
VOACAMINE A citraconoyl group that has formula C43H52N4O5.
WS-898
WS-917
ZIDOVUDINE A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
ZOSUQUIDAR
CHENODEOXYCHOLIC ACID A dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively.
CHOLIC ACID A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
GLYBURIDE An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
GLYCOCHENODEOXYCHOLIC ACID A bile acid glycine conjugate having 3alpha,7alpha-dihydroxy-5beta-cholan-24-oyl as the bile acid component.
GS-9256
HYDROXYPROGESTERONE CAPROATE (USP)
LAPATINIB
MARALIXIBAT
ODEVIXIBAT
MITOMYCIN
HALOPERIDOL DECANOATE
(S)-VERAPAMIL
ABACAVIR
ALVOCIDIB HYDROCHLORIDE
BENZBROMARONE
BUTHIONINE SULFOXIMINE
CISPLATIN A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary.
CLOZAPINE A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia.
DEXVERAPAMIL
DIPYRIDAMOLE A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
DOCETAXEL ANHYDROUS
DOFEQUIDAR FUMARATE
DROLOXIFENE A stilbenoid that has formula C26H29NO2.
DULANERMIN
EMTRICITABINE
EPIGALLOCATECHIN GALLATE
EPIRUBICIN
ESTROGENS, CONJUGATED (USP)
ETOPOSIDE A furonaphthodioxole that has formula C29H32O13.
FENTANYL CITRATE
INDOMETHACIN
IRINOTECAN HYDROCHLORIDE
LAMIVUDINE
LEUCOVORIN CALCIUM
MELPHALAN A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
MK-571
MONTELUKAST SODIUM
NAXTARUBICIN
NOVOBIOCIN
OFLOXACIN An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
OXALIPLATIN A platinum coordination entity that has formula C6H14N2.C2O4.Pt.
PILOCARPINE HYDROCHLORIDE
PIRARUBICIN
PROTEASE INHIBITOR
RIMONABANT
SAQUINAVIR MESYLATE
SODIUM BUTYRATE
SULFINPYRAZONE A pyrazolidine that has formula C23H20N2O3S.
TENIPOSIDE
TENOFOVIR
THERAPEUTIC CYTOKINE
THYMIDINE A pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase.
TIOPRONIN
TROXACITABINE
WP814
ALKYLSULFONATE COMPOUND
APIXABAN A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases.
CEFACLOR ANHYDROUS
CEFADROXIL ANHYDROUS
CEFAMANDOLE
CEFMETAZOLE
CEFOPERAZONE
CEFOXITIN SODIUM
CEFTRIAXONE A cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups.
CEFUROXIME AXETIL
CEPHALEXIN ANHYDROUS
CEPHRADINE A cephalosporin with a methyl substituent at position 3, and a (2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetamido substituent at position 7, of the cephem skeleton.
CYCLOPHOSPHAMIDE ANHYDROUS
DEFERASIROX
DESMETRAMADOL
DICLOFENAC SODIUM
LACOSAMIDE
LUMEFANTRINE
OFTASCEINE
PAK-104P
PEMETREXED DISODIUM
SN-38 A pyranoindolizinoquinoline that has formula C22H20N2O5.
VORICONAZOLE A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4.
BUSULFAN
CYTARABINE A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond.
MONOMETHYL AURISTATIN E
MORPHINE GLUCURONIDE
ADEFOVIR DIPIVOXIL
ANTIVIRAL AGENT
ESTRADIOL DISULFATE
FUROSEMIDE A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
GANCICLOVIR An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
GLUCARPIDASE
INDINAVIR
METHOTREXATE A pteridine that has formula C20H22N8O5.
MISOPROSTOL A diastereoisomeric mixture composed of approximately equal amounts of a double racemate of four of the sixteen possible diastereoisomers of methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate that is racemic prostaglandin E1 which is lacking the hydroxy group at position 15, but which has an additional hydroxy group at position 16. It is a synthetic prostaglandin E1 analogue, used in the treatment of gastric and duodenal ulcers. A weak abortifacient, it is also used for cervical ripening prior to surgical termination of pregnancy. The (11R,16S)-diastereoisomer is the pharmacologically active form.
SUNITINIB A pyrrole that has formula C22H27FN4O2.
THIOGUANINE
CANNABIDIOL An organic molecular entity that has formula C21H30O2.
COMPOUND 2 [PMID: 22380603]
FLOXURIDINE
SILDENAFIL
CHONDROITIN SULFATES
HEPARAN SULFATE A linear polysaccharide in which the backbone consists of a variably sulfated repeating disaccharide unit.
SODIUM CHLORIDE An inorganic chloride salt having sodium(1+) as the counterion.
THALIDOMIDE
ACETOHEXAMIDE An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a p-acetylphenylsulfonyl group, while a hydrogen attached to the other nitrogen is replaced by a cyclohexyl group.
BERBERINE CHLORIDE
BERBERRUBINE
CHLORPROPAMIDE An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
DIAZOXIDE CHOLINE
GLICLAZIDE
GLIMEPIRIDE A N-acylurea that has formula C24H34N4O5S.
GLIPIZIDE
GLIQUIDONE
METFORMIN A member of the class of guanidines that is the 1,1-dimethyl derivative of biguanide.
MITIGLINIDE
MITIGLINIDE CALCIUM DIHYDRATE
NAMINIDIL
NATEGLINIDE
REPAGLINIDE
SARAKALIM
TIFENAZOXIDE
TOLAZAMIDE
TOLBUTAMIDE An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
TOLBUTAMIDE SODIUM
COMPOUND 13B [PMID: 19101153]
DEXMEDETOMIDINE HYDROCHLORIDE
MINOXIDIL A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6.
NICORANDIL
PINACIDIL
ANHYDROUS TACROLIMUS
AXITINIB
CAPECITABINE
CHEMBL:CHEMBL428402
CHEMBL:CHEMBL488910
CHORIOGONADOTROPIN ALFA
DIFLOMOTECAN
ELTROMBOPAG
ERLOTINIB HYDROCHLORIDE
FELODIPINE The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
GENISTEIN 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
IBRUTINIB A member of the class of acrylamides that is (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies.
KETOCONAZOLE A N-carbonylpiperazine that has formula C26H28Cl2N4O4.
LENVATINIB
N-DESMETHYLTAMOXIFEN A stilbenoid that has formula C25H27NO.
NILOTINIB
NITROFURANTOIN, MACROCRYSTALS
NOBILETIN A flavonoid that has formula C21H22O8.
NORCLOBAZAM
PRASTERONE
PRAZOSIN A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
RAMIPRIL A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
RESMETIROM
RETUSIN
RISPERIDONE A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
SEPIAPTERIN A pterin that has formula C9H11N5O3.
SILYMARIN
SULFASALAZINE An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
TELMISARTAN
TOPOTECAN HYDROCHLORIDE
THERAPEUTIC HORMONE
DOXIFLURIDINE A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.
DO264
ORLISTAT
ABX-1431
KT-109
WWL123
WWL70
1-AZAKENPAULLONE
ACYCLOVIR An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9.
ADAVOSERTIB
ADENOSINE TRIPHOSPHATE
ALISERTIB
ALSTERPAULLONE
ASCIMINIB
ASCIMINIB HYDROCHLORIDE
AST-487
AT-9283
AT9283
AZACITIDINE
AZD-0424
AZM-475271
BCR-ABL INHIBITOR GNF-2
BLINATUMOMAB
BO1
BOSUTINIB
BOSUTINIB MONOHYDRATE
CABOZANTINIB S-MALATE
CEDIRANIB
CELECOXIB
CENISERTIB
CEP-11981
CHEMBL:CHEMBL379975
CHEMBL:CHEMBL546797
COMPOUND 24 [PMID: 23441572]
COMPOUND 2C [PMID: 24900538]
COMPOUND 33A [PMID: 35944901]
COMPOUND 8H [PMID: 21561767]
CP-547632
CYC-116
DDR1/2 INHIBITOR 5N
DOVITINIB
ECF506
EMBIBATINIB
ENMD-2076
ENTRECTINIB
FLUMATINIB
FLUMBATINIB
FORETINIB
GNF-5
HYDROXYUREA A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.
ILORASERTIB
IMATINIB MESYLATE
INOTUZUMAB OZOGAMICIN
JNJ-7706621
KENPAULLONE
KW-2449
MASITINIB A member of the class of benzamides that is the carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine. It is a highly selective oral tyrosine kinase inhibitor.
MERIBATINIB
MLN-8054
NILOTINIB HYDROCHLORIDE MONOHYDRATE
NVP-TAE684
OLVEREMBATINIB
OMACETAXINE
OMACETAXINE MEPESUCCINATE
PAZOPANIB
PD166285
PD173955
PEXMETINIB
PONATINIB A benzamide obtained by the formal condensation of the carboxy group of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid with the anilino group of 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline.
PONATINIB HYDROCHLORIDE
PP-121
PP2
PROGESTERONE A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
QUERCETIN A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions.
RADOTINIB
REBASTINIB
REGORAFENIB
RELCOBATINIB
RISVODETINIB
RUSERONTINIB
SARACATINIB
SIAIS178
TOZASERTIB
TRAMETINIB DIMETHYL SULFOXIDE
UMBRALISIB TOSYLATE
VAMOTINIB
VANDETANIB A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
VODOBATINIB
XL-228
XL228
ZAK INHIBITOR 6P
PEGYLATED RECOMBINANT HUMAN ARGINASE I BCT-100
CLESACOSTAT
COMPOUND 21 [PMID: 23981033]
CP-640186
FIRSOCOSTAT
OLUMACOSTAT GLASARETIL
PF-05175157
TOFA
A-908292
COMPOUND 2E [PMID: 31900320]
TRIHEPTANOIN
K-604
ACETYLCHOLINE
AD015
ALACEPRIL
ARGIPRESSIN
ASPIRIN
BENAZEPRIL A benzazepine that has formula C24H28N2O5.
BENAZEPRIL HYDROCHLORIDE
BENAZEPRILAT
BUMETANIDE A member of the class of benzoic acids that is 4-phenoxybenzoic acid in which the hydrogens ortho to the phenoxy group are substituted by butylamino and sulfamoyl groups. Bumetanide is a diuretic, and is used for treatment of oedema associated with congestive heart failure, hepatic and renal disease.
BUPROPION HYDROCHLORIDE
CANDOXATRIL The 2,3-dihydro-1H-inden-5-yl ester of the active enantiomer of candoxatrilat. Candoxatril is an orally active prodrug of candoxatrilat, a potent neutral endopeptidase (NEP, neprilysin) inhibitor used in the treatment of chronic heart failure.
CAPTOPRIL A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug.
CGS-27023A
CILAZAPRIL
DELAPRIL
DESERPIDINE
ENALAPRIL MALEATE
ENALAPRILAT
ENALAPRILAT ANHYDROUS
ENZYME INHIBITOR
FASIDOTRIL
FASIDOTRILAT
FOSINOPRIL A phosphinate ester-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. It is used for the treatment of hypertension and heart failure. A pro-drug, it is hydrolysed in vivo to the corresponding phosphininc acid, fosinoprilat, which is the active metabolite.
FOSINOPRIL SODIUM
GALLOPAMIL
ILEPATRIL
IMIDAPRIL
IMIDAPRILAT
LISINOPRIL A dipeptide that has formula C21H31N3O5.
LISINOPRIL ANHYDROUS
LISINOPRIL-TRYPTOPHAN
MALATHION A diester that is butanedioate substituted by a (dimethoxyphosphorothioyl)sulfanediyl group at position 2.
MOEXIPRIL
MOEXIPRIL HYDROCHLORIDE
NITROPRUSSIDE An iron coordination entity that has formula C5FeN6O.
PERINDOPRIL An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline
PERINDOPRIL ARGININE
PERINDOPRIL ERBUMINE
PERINDOPRILAT
QUINAPRIL An isoquinoline that has formula C25H30N2O5.
QUINAPRIL HYDROCHLORIDE
QUINAPRILAT
RAMIPRILAT A dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
RESCINNAMINE
RXP-407
SALVIANOLIC ACID B
SPIRAPRIL
SPIRAPRIL HYDROCHLORIDE
SPIRAPRILAT
TEMOCAPRIL HYDROCHLORIDE
TORSEMIDE
TRANDOLAPRIL
TRANDOLAPRILAT
VORINOSTAT
ZOFENOPRIL
ABZ-SER-PRO-TYR(NO2)-OH
ALUNACEDASE ALFA
BCY15291
COMPOUND 28 [PMID: 18324760]
CPS4
DX600
MLN-4760
ORE-1001
XNT [PMID: 18391097]
(-)-ISATISPIRONEOL A
6-AMINONICOTINAMIDE A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 6-aminonicotinic acid with ammonia. An inhibitor of the NADP(+)-dependent enzyme, 6-phosphogluconate dehydrogenase, it interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, such as cisplatin, in killing cancer cells.
8-AZAGUANINE A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
ACHE REACTIVATOR 2
ACOTIAMIDE
ACOTIAMIDE HYDROCHLORIDE
AMBENONIUM
AMBENONIUM CHLORIDE A symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
AMOCARZINE
APIGENIN A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7.
BENZGALANTAMINE GLUCONATE
BETAMETHASONE A glucocorticoid that has formula C22H29FO5.
BUNTANETAP
BW284C51
COMPOUND 2F [JIANG ET AL., 2018]
DEMECARIUM BROMIDE
DESOXYCORDIFOLINE
DIANHYDROGALACTITOL
DISTIGMINE
DONECOPRIDE
DONEPEZIL Donepezil is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
DONEPEZIL HYDROCHLORIDE
ECHOTHIOPHATE IODIDE
ECOTHIOPATE
EDROPHONIUM CATION
EDROPHONIUM CHLORIDE
EPTASTIGMINE
GALANTAMINE
GALANTAMINE HYDROBROMIDE
HEXAFLUORENIUM BROMIDE
HUPERZINE A A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity.
ISOFLUROPHATE
ITOPRIDE
LADOSTIGIL
LATREPIRDINE
MAGNESIUM CHLORIDE ANHYDROUS
METHANESULFONYL FLUORIDE
MIMOPEZIL
MINAPRINE
MINAPRINE HYDROCHLORIDE
NEOSTIGMINE A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
NEOSTIGMINE METHYLSULFATE
PHENSERINE
PHYSOSTIGMINE An indole alkaloid that has formula C15H21N3O2.
PHYSOSTIGMINE SALICYLATE An azaheterocycle salicylate salt that has formula C22H27N3O5.
PRALIDOXIME CATION
PRALIDOXIME CHLORIDE
PROPANIDID
PYRIDOSTIGMINE
PYRIDOSTIGMINE BROMIDE
RADIOSENSITIZING AGENT
RIVASTIGMINE
RIVASTIGMINE TARTRATE
SKIMMIANINE
SURONACRINE MALEATE
TACRINE
TACRINE HYDROCHLORIDE
TURBINATINE
AQ-13
CHLOROQUINE An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
CANVERIXIN
CXCL11 chemokine (C-X-C motif) ligand 11|Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
CXCL12&ALPHA;
PLERIXAFOR
TC14012
CCL19 chemokine (C-C motif) ligand 19|This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]
CCL21 chemokine (C-C motif) ligand 21|This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
CCL25 chemokine (C-C motif) ligand 25|This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
BEMPEDOIC ACID
BMS-303141
GLUCAGON (RDNA)
NDI-091143
ACETYLCYSTEINE
ANTIOXIDANT A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324.
ANTISERUM
THERAPEUTIC CORTICOSTEROID
AKT INHIBITOR VIII
CEFDINIR A cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups.
CHEMBL:CHEMBL1520282
CHEMBL:CHEMBL527307
CHEMBL:CHEMBL528734
CHEMBL:CHEMBL598477
CHEMBL:CHEMBL602561
CHEMBL:CHEMBL84440
FIDUXOSIN HYDROCHLORIDE
PYRIMETHAMINE
MODIFIED VACCINIA ANKARA-BAVARIAN NORDIC
SIPULEUCEL-T
ANALGESIC AGENT
RECOMBINANT MACROPHAGE COLONY-STIMULATING FACTOR
STREPTOZOCIN
TETRADECANOYLPHORBOL ACETATE
COMPOUND 9 [PMID: 3514912]
EXAMPLE 265 [WO2019097515A1]
GEMCITABINE A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.
TIMBETASIN
ENVIRONMENTAL ESTROGEN
ETHINYL ESTRADIOL
DEXAMETHASONE A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
PANOBINOSTAT
RECOMBINANT MONOCYTE CHEMOATTRACTANT PROTEIN-1
CAFFEINE A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
BMS-986260
CHEMBL:CHEMBL1997335
COMPOUND 13A [PMID: 23639540]
COMPOUND 13D [PMID: 23639540]
COMPOUND 13R [PMID: 23639540]
COMPOUND 7 [NGUYEN ET AL., 2023]
COMPOUND 8 [PMID: 17480064]
DACTOLISIB An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.
DIBOTERMIN ALFA
EPTOTERMIN ALFA
FIDRISERTIB
ITACNOSERTIB
K02288
LDN-214117
MEK-1/MEKK-1 INHIBITOR E6201
ML347
MOMELOTINIB
MOMELOTINIB DIHYDROCHLORIDE MONOHYDRATE
PACRITINIB CITRATE
RG-1530
TANDUTINIB
ZILURGISERTIB
GALUNISERTIB
VACTOSERTIB
SB-431542
BIMAGRUMAB
SOTATERCEPT
RAMATERCEPT
ASCRINVACUMAB
DALANTERCEPT
HESPERADIN
PANULISIB
BISOPROLOL A secondary amine that has formula C18H31NO4.
AMITRIPTYLINE HYDROCHLORIDE
ANTIMALARIAL AGENT
CLADRIBINE 2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia.
COFORMYCIN An N-glycosyl in which (8R)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol is attached to ribofuranose via a beta-N(3)-glycosidic bond. compound The parent of the class of coformycins.
CORDYCEPIN A 3'-deoxyribonucleoside that has formula C10H13N5O3.
DIDEOXYADENOSINE
DIFFERENTIATION INDUCER
EHNA A purine derivative having an adenine skeleton substituted at N-9 with a erythro-2-hydroxynonan-3-yl group; relative configuration.
ELAPEGADEMASE
FLUDARABINE
LEVODOPA
METHYLMERCAPTOPURINE RIBOSIDE
PENTOSTATIN
RECOMBINANT PROTHYMOSIN ALPHA
SELENIUM
THERAPEUTIC INTERLEUKIN
TILARGININE
ADERBASIB
COMPOUND 25 [PMID: 18068976]
GI254023X
ILOMASTAT
INCB7839
MARIMASTAT A tricarboxylic acid triamide that has formula C15H29N3O5.
APRATASTAT
BMS-561392
CHEMBL:CHEMBL599255
IK-862
INFLIXIMAB
INCB3619
USTEKINUMAB
COMPOUND 12C [PMID: 16516466]
LEVONORGESTREL A 17beta-hydroxy steroid that has formula C21H28O2.
APADAMTASE ALFA
COMPOUND 15C [PMID: 21536437]
AGG-523
ALDUMASTAT
RECOMBINANT TUMOR NECROSIS FACTOR FAMILY PROTEIN
BAY-9835
BUPRENORPHINE A morphinane alkaloid that is 7,8-dihydromorphine 6-O-methyl ether in which positions 6 and 14 are joined by a -CH2CH2- bridge, one of the hydrogens of the N-methyl group is substituted by cyclopropyl, and a hydrogen at position 7 is substituted by a 2-hydroxy-3,3-dimethylbutan-2-yl group.
ADENOSINE MONOPHOSPHATE
CHEMBL:CHEMBL401844
ST034307
KH7
LRE1
TDI-11861
FD1
SKF-83566
FD6
NKY80
ALBUTEROL SULFATE
DALCETRAPIB
BAY 55-9837
INSULIN, REGULAR, HUMAN
M65
MAXADILAN
MK-0893
N-STEARYL-[NLE17] NEUROTENSIN-(6-11)/VIP-(7-28)
NALOXONE HYDROCHLORIDE
PACAP-27
PACAP-38
PG 97-269
PG 99-465
RO 25-1553
VIP vasoactive intestinal peptide|The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]
[125I]PACAP-27
[125I]VIP (HUMAN, MOUSE, RAT)
[125I][AC-HIS1]PACAP-27
[ALA11,22,28]VIP
[ARG16]CHICKEN SECRETIN
[LYS15,ARG16,LEU27]VIP-(1-7)/GRF-(8-27)-NH2
LECITHIN
SYNAPTAMIDE
NB23-BI
BECLOMETHASONE DIPROPIONATE
AJ-292
ACETALDEHYDE The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
FOMEPIZOLE A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
NITREFAZOLE
NALTREXONE An organic heteropentacyclic compound that is 4,5-epoxymorphinan-6-one substituted by a cyclopropylmethyl group at position 17 and hydroxy groups at positions 3 and 14. A mu-opioid receptor antagonist, it is used to treat alcohol dependence.
TRETINOIN
DEHYDRATED ALCOHOL
CAVOSONSTAT
N6022
ANTIHYPERTENSIVE AGENT Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
HYDRALAZINE The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
METHYLDOPA ANHYDROUS
A134974
ABT702
BLEOMYCIN A glycopeptide antibiotic produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2.
DABIGATRAN An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-beta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.
DACARBAZINE A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.
DIDANOSINE A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen.
LOMUSTINE
CHEMBL:CHEMBL2063510
CHEMBL:CHEMBL501993
ENIBARCIMAB
MEK INHIBITOR PD-98059
PAROXETINE HYDROCHLORIDE, HEMIHYDRATE
(R)-PIA
(R,S)-PHPNECA
(S)-PIA
2'-ME-CCPA
2-CHLOROADENOSINE
2-HEXYNYL-NECA
3-ISOBUTYL-1-METHYL-7H-XANTHINE
4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL
5-CL-5-DEOXY-(&PLUSMN;)-ENBA
8-CYCLOPENTYLTHEOPHYLLINE
ABEA-X-BY630
ADENOSINE A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.
AMINOPHYLLINE
AMP579
APADENOSON
APAXIFYLLINE
AS100
AS70
AS99
ATL802
BAY 60-6583
BAY1067197
BINODENOSON
CAFFEINE CITRATE
CAPADENOSON
CCPA
CGS 15943
CGS 21680
CHEMBL:CHEMBL27508
CHEMBL:CHEMBL303124
CHEMBL:CHEMBL59532
CHROMOCARB
COMPOUND 10 [PMID: 31306001]
CP608,039
CPFPX
CVT-6883
CYCLOPENTYLADENOSINE
DEFIBROTIDE
DERENOFYLLINE
DPCPX An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
DU172
FK-453
FK352B
FR194921
GS-9667
GS9667
GW493838
HEMADO
IMARADENANT
ISTRADEFYLLINE
KF26777
L-97-1
LAS38096
LUF5831
LUF5962
LUF5981
LUF7602
MEFLOQUINE A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown.
MIPS521
MRE 2029F20
MRE 3008F20
MRS1191
MRS1523
MRS1754
MRS3558
MRS5151
MRS7469
MSX-2
NAMODENOSON
NAXIFYLLINE
NECA
NELADENOSON
OXTRIPHYLLINE
PBF-680
PD81723
PENECA
PENTOXIFYLLINE
PICLIDENOSON
PRELADENANT
PSB-10
PSB-11
PSB1115
PSB603
REGADENOSON ANHYDROUS
ROLOFYLLINE
RPR749
SCH 58261
SCH442416
SELODENOSON
ST-1535
T-62
TCPA
TECADENOSON
THEOPHYLLINE A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.
THEOPHYLLINE SODIUM GLYCINATE
TONAPOFYLLINE
TRABODENOSON
VIPADENANT
VPC171
WRC-0571
XANTHINE AMINE CONGENER
[3H]DPCPX
AB-MECA
APNEA Lack of breathing with no movement of the respiratory muscles and no exchange of air in the lungs. This term refers to a disposition to have recurrent episodes of apnea rather than to a single event.
BVT.115959
CGS 24012
CIFORADENANT
COMPOUND 4G [PMID: 22220592]
CPX
CV-1674
CV-1808
DEXEFAROXAN
ETRUMADENANT
EVODENOSON
FLAVONE The simplest member of the class of flavones that consists of 4H-chromen-4-one bearing a phenyl substituent at position 2.
GALANGIN A 7-hydroxyflavonol with additional hydroxy groups at positions 3 and 5 respectively.
GR79236
GW-328267
KF 17837S
LJ-4517
METRIFUDIL
MORIN A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
MRS1041
MRS1042
MRS1065
MRS1066
MRS1084
MRS1086
MRS1088
MRS1093
MRS1132
MRS923
MRS928
N(6)-CYCLOHEXYLADENOSINE
PBF-509
PBF-999
PSB36
REGADENOSON
SAKURANETIN A flavonoid phytoalexin that is (S)-naringenin in which the hydroxy group at position 7 is replaced by a methoxy group.
SIPAGLADENANT
SONEDENOSON
TOZADENANT
UK-432,097
UK-432097
VISNAGIN An oxacycle that has formula C13H10O4.
[3H]CGS 21680
[3H]ZM 241385
3-ISOBUTYL-8-PYRROLIDINOXANTHINE
AB-NECA
ADENOSINE A2B RECEPTOR ANTAGONIST PBF-1129
ALLOXAZINE A benzo[g]pteridine-2,4-dione that has formula C10H6N4O2.
AS101
AS16
AS74
AS94
AS95
AS96
BAY-545
BW-A1433
DAX
DEPX
I-ABOPX
ISAM-140
LAS101057
MRS1220
OSIP339391
PSB-0788
PSB-12105
QAF805
VIDARABINE
XANTHINE A purine nucleobase found in humans and other organisms.
XCC
[125I]ABOPX
2-PHENYLETHYLYL-ADENOSINE DERIVATIVE
CA200645
CHEMBL:CHEMBL382194
CIPARGAMIN
COMPOUND 6C [PMID: 34435786]
DEXNIGULDIPINE
FLAVANONE The simplest member of the class of flavanones that consists of flavan bearing an oxo substituent at position 4.
I-ABA
LUF6000
LUF6096
MPC-MECA
MRE 3010F20
MRS1067
MRS1097
MRS1177
MRS1186
MRS1476
MRS1486
MRS1505
MRS5698
MRS5980
MRS7799
MRS8054
MRS8247
NICARDIPINE
VANOXERINE An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
VUF5574
VUF8504
VUF8507
[125I]AB-MECA
[3H]HEMADO
[3H]PSB-11
&RHO;-DA1A
(+)-ADRENALINE
(+)-CYCLAZOSIN
5-METHYLURAPIDIL
A-119637
A-123189
A61603
ALFUZOSIN A tetrahydrofuranol that has formula C19H27N5O4.
ALFUZOSIN HYDROCHLORIDE
AMIODARONE HYDROCHLORIDE
ASENAPINE
AVIPTADIL
BENZPHETAMINE Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity.
BESIPIRDINE
BETHANIDINE
BMY-7378
BODIPY FL-PRAZOSIN
BUCINDOLOL HYDROCHLORIDE
BUNAZOSIN
CABERGOLINE An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.
CARVEDILOL A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
CARVEDILOL PHOSPHATE
CIRAZOLINE
CYPROHEPTADINE HYDROCHLORIDE
DABUZALGRON
DAPIPRAZOLE
DAPIPRAZOLE HYDROCHLORIDE
DEBRISOQUIN
DEXTROAMPHETAMINE SULFATE
DIPIVEFRIN HYDROCHLORIDE
DISULFIRAM An organic disulfide that is 1,1'-[disulfanediylbis(carbonothioylimino)]diethane substituted by ethyl groups at the N atom. An EC 1.2.1.3 [aldehyde dehydrogenase (NAD+)] inhibitor, it is used as an alcohol deterrent.
DOPAMINE Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group.
DOXAZOSIN MESYLATE
DRONEDARONE
DROXIDOPA A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension
EPHEDRINE
EPHEDRINE HYDROCHLORIDE
EPHEDRINE SULFATE
EPINEPHRINE
EPINEPHRINE BITARTRATE
ERGOLOID MESYLATES
ERGOLOID MESYLATES, USP
ERGOTAMINE TARTRATE
HEAT (BE2254)
HYDROXYAMPHETAMINE HYDROBROMIDE
ILOPERIDONE
INDORAMIN
ISOXSUPRINE HYDROCHLORIDE
KETANSERIN
LABETALOL A secondary amino compound formally derived from ammonia by replacing two of the hydrogens by 2-(3-carbamoyl-4-hydroxyphenyl)-2-hydroxyethyl and 4-phenylbutan-2-yl groups. It is an adrenergic antagonist used to treat high blood pressure.
LABETALOL HYDROCHLORIDE
LISDEXAMFETAMINE DIMESYLATE
LISURIDE
MEDETOMIDINE
MEPHENTERMINE
MEPHENTERMINE SULFATE
METARAMINOL
METARAMINOL BITARTRATE
METHAMPHETAMINE A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
METHOTRIMEPRAZINE
METHOXAMINE
METHOXAMINE HYDROCHLORIDE
MIANSERIN
MIDODRINE An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
MIDODRINE HYDROCHLORIDE
MOXISYLYTE
MT-1207
NAFTOPIDIL
NAN 190 An N-alkylpiperazine that consists of (2-methoxyphenyl)piperazine in which the amine hydrogen is substituted by a 4-(2-phthalimido)butyl group.
NAPHAZOLINE
NAPHAZOLINE HYDROCHLORIDE
NICERGOLINE
NIGULDIPINE A diarylmethane that has formula C36H39N3O6.
NOREPINEPHRINE
NOREPINEPHRINE BITARTRATE
NORTRIPTYLINE An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
NS-49
OLANZAPINE A benzodiazepine that has formula C17H20N4S.
OXYMETAZOLINE HYDROCHLORIDE
PARDOPRUNOX
PERICIAZINE
PHENDIMETRAZINE
PHENOXYBENZAMINE
PHENOXYBENZAMINE HYDROCHLORIDE
PHENTOLAMINE
PHENTOLAMINE MESYLATE
PHENYLEPHRINE A member of the class of the class of phenylethanolamines that is 2-(methylamino)ethanol substituted by a 3-hydroxyphenyl group at position 1.
PHENYLEPHRINE BITARTRATE
PHENYLEPHRINE HYDROCHLORIDE
PHENYLPROPANOLAMINE
PHENYLPROPANOLAMINE HYDROCHLORIDE
PHENYLPROPANOLAMINE POLISTIREX
PIRIBEDIL
PRAZOSIN HYDROCHLORIDE
PROMAZINE
PROPIOMAZINE
PSEUDOEPHEDRINE POLISTIREX
RAUWOLFIA SERPENTINA
RAUWOLFIA SERPENTINA (USP)
RITANSERIN A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
RO-70-0004
ROXINDOLE A ring assembly that has formula C23H26N2O.
RS-100329
RS-17053
SENREBOTASE
SERTINDOLE
SILODOSIN
SNAP5089
SPIPERONE An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
SPIROXATRINE
TAMSULOSIN HYDROCHLORIDE
TEDATIOXETINE
TERAZOSIN A piperazine that has formula C19H25N5O4.
TERAZOSIN HYDROCHLORIDE
TERGURIDE
TETRAHYDROZOLINE HYDROCHLORIDE
THIORIDAZINE A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
TOLAZOLINE
TOLAZOLINE HYDROCHLORIDE
TRAZODONE An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
TRIFLUOPERAZINE A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
TRIMIPRAMINE MALEATE
UPIDOSIN
WB 4101
XYLOMETAZOLINE HYDROCHLORIDE
ZIPRASIDONE A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
[125I]HEAT (BE2254)
AH 11110
COMPOUND 12 [PMID: 26238322]
L-765314
MAMBA TOXIN CM-3
MUSCARINIC TOXIN &BETA;
QUETIAPINE FUMARATE
REC 15/2615
RHO-TIA
(S)-41
CLONIDINE HYDROCHLORIDE
CYPROTERONE ACETATE A chlorinated steroid that has formula C24H29ClO4.
DIBENAMINE
ERGOTAMINE A peptide ergot alkaloid that is dihydroergotamine in which a double bond replaces the single bond between positions 9 and 10.
METOPROLOL SUCCINATE
PAPAVERINE A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
RX18
SKF 105854
TRIMAZOSIN
URAPIDIL
5-(N,N-HEXAMETHYLENE)-AMILORIDE
APOMORPHINE
APRACLONIDINE An imidazoline compound having a 4-amino-2,6-dichloroanilino group at the 2-position.
APRACLONIDINE HYDROCHLORIDE
ARC-239
ATIPAMEZOLE
ATROPINE A racemate composed of equimolar concentrations of (S)- and (R)-atropine . It is obtained from deadly nightshade (Atropa belladonna) and other plants of the family Solanaceae.
BRIMONIDINE A quinoxaline derivative that has formula C11H10BrN5.
BRIMONIDINE TARTRATE
BRL44408
BROMOCRIPTINE An indole alkaloid that has formula C32H40BrN5O5.
C10 (HOMOBIVALENT 4-AMINOQUINOLINE)
DIPIVEFRIN The dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.
ESMIRTAZAPINE
ESMIRTAZAPINE MALEATE
ETHYLISOPROPYLAMILORIDE
FADOLMIDINE
FADOLMIDINE HYDROCHLORIDE
FENOLDOPAM A benzazepine that has formula C16H16ClNO3.
FIPAMEZOLE
GUANABENZ
GUANABENZ ACETATE
GUANFACINE HYDROCHLORIDE
GUANIDINE HYDROCHLORIDE
IDAZOXAN An imidazoline that has formula C11H12N2O2.
LEVONORDEFRIN
LOFEXIDINE
LOFEXIDINE HYDROCHLORIDE
LURASIDONE HYDROCHLORIDE
MEPERIDINE HYDROCHLORIDE
METHYLDOPATE HYDROCHLORIDE
MILNACIPRAN
MIRTAZAPINE A tetracyclic antidepressant that has formula C17H19N3.
MK-912
MOXONIDINE
MUSCARINIC TOXIN 3
PERGOLIDE A diamine that is ergoline in which the beta-hydrogen at position 8 is replaced by a (methylthio)methyl group and the hydrogen attached to the piperidine nitrogen (position 6) is replaced by a propyl group. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used as the mesylate salt in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.
RAUWOLSCINE A methyl 17-hydroxy-20xi-yohimban-16-carboxylate that has formula C21H26N2O3.
REMIFENTANIL HYDROCHLORIDE
RS79948
RX821002
TASIPIMIDINE SULFATE
TIZANIDINE HYDROCHLORIDE
XYLAZINE
XYLOMETAZOLINE
YOHIMBINE An indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina.
[125I]P-IODOCLONIDINE
[3H]MK-912
[3H]RAUWOLSCINE
ETOMIDATE The ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity.
OPC-28326
RACEPINEPHRINE
ZOTEPINE
ACEBUTOLOL An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.
ALL-TRANS-4-OXO-RETINOIC ACID
AMEZINIUM
AMOSULALOL
BETAXOLOL A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective beta1-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure.
CYCLOBENZAPRINE 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
DIHYDROERGOCRISTINE
EGIS-11150
ESMOLOL A carboxylic ester that is methyl 3-(4-hydroxyphenyl)propanoate in which the hydrogen attached to the phenoic hydroxy group is substituted by a 2-hydroxy-3-(isopropylamino)propyl group. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery.
IDAZOXAN HYDROCHLORIDE
JP1302
METOPROLOL A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
NADOLOL Nadolol is a diastereoisomeric mixture consisting of equimolar amounts of the four possible 2,3-cis-isomers of 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol.
NEBIVOLOL HYDROCHLORIDE
ORM-10921
ORM-12741
ORM-13070 C-11
PINDOLOL A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol.
PROPYLHEXEDRINE
RILMENIDINE
SOTALOL A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
TETRAHYDROZOLINE
TETRASUL
(-)-RO 363
7-METHYLCYANOPINDOLOL
ABEDITEROL
ACEBUTOLOL HYDROCHLORIDE
AJMALICINE
ALPRENOLOL
ANISODAMINE
ANISODINE
ARBUTAMINE
BETAXOLOL HYDROCHLORIDE
BEVANTOLOL A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by 3-methylphenyl and one of the hydrogens attached to the nitrogen is substituted by 2-(3,4-dimethoxyphenyl)ethyl. A beta1 adrenoceptor antagonist, it has been shown to be as effective as other beta-blockers for the treatment of angina pectoris and hypertension.
BI-167107
BISOPROLOL FUMARATE
BRETYLIUM
BRL 37344
BRL35135
BUDIODARONE
BUFURALOL A benzofuran that has formula C16H23NO2.
BUNITROLOL
BUPRANOLOL
CARAZOLOL
CARTEOLOL A quinolone that has formula C16H24N2O3.
CARTEOLOL HYDROCHLORIDE
CGP12177
CGP20712A
CHEMBL:CHEMBL1793796
CICLOPROLOL
CIMATEROL
CLENBUTEROL
CYANOPINDOLOL
DENOPAMINE
DESIPRAMINE A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
DICHLOROISOPROTERENOL
DILEVALOL HYDROCHLORIDE
DOBUTAMINE A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.
DOBUTAMINE HYDROCHLORIDE
DOPAMINE HYDROCHLORIDE
ESMOLOL HYDROCHLORIDE
FENOTEROL
FLECAINIDE ACETATE
FORMOTEROL FUMARATE
FOSLEVODOPA
H87/07
ICI-89406
INDACATEROL
ISOETHARINE
ISOPROTERENOL HYDROCHLORIDE
ISOPROTERENOL SULFATE
LANDIOLOL
LANDIOLOL HYDROCHLORIDE
LEVOBETAXOLOL
LEVOBETAXOLOL HYDROCHLORIDE
LEVOBUNOLOL A cyclic ketone that is 3,4-dihydronaphthalen-1-one substituted at position 5 by a 3-(tert-butylamino)-2-hydroxypropoxy group (the S-enantiomer). A non-selective beta-adrenergic antagonist used (as its hydrochloride salt) for treatment of glaucoma.
LEVOBUNOLOL HYDROCHLORIDE
LEVOSALBUTAMOL
LK 204-545
LY377604
MEPINDOLOL
METIPRANOLOL 3-(Propan-2-ylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by a 4-acetoxy-2,3,5-trimethylphenoxy group. A non-cardioselective beta-blocker, it is used to lower intra-ocular pressure in the management of open-angle glaucoma.
METIPRANOLOL HYDROCHLORIDE
METOPROLOL FUMARATE
METOPROLOL TARTRATE
MIRABEGRON
MURAGLITAZAR
NDD-713
NDD-825
NIHP
NIP
NORADRENALINE A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted.
OT-730
OXPRENOLOL
OXPRENOLOL HYDROCHLORIDE
PENBUTOLOL
PENBUTOLOL SULFATE
PRACTOLOL
PRENALTEROL An aromatic ether that has formula C12H19NO3.
PRONETALOL
PROPAFENONE An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
PROPAFENONE HYDROCHLORIDE
PROTOKYLOL HYDROCHLORIDE
SALMETEROL
SOLABEGRON
SOTALOL HYDROCHLORIDE
SR59230A
SUFENTANIL An anilide resulting from the formal condensation of the aryl amino group of 4-(methoxymethyl)-N-phenyl-1-[2-(2-thienyl)ethyl]piperidin-4-amine with propanoic acid.
T-0509
TARANABANT
TERBUTALINE A member of the class of phenylethanolamines that is catechol substuted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.
TERTATOLOL
TIMOLOL 1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.
TIMOLOL MALEATE
XAMOTEROL
[125I]ICYP
[3H](-)CGP12177
3-O-METHYLQUERCETIN
APD-209
ARFORMOTEROL
ARFORMOTEROL TARTRATE
AZD3199
BAMBUTEROL
BAMOSIRAN
BATEFENTEROL
BEDORADRINE SULFATE
BITOLTEROL MESYLATE
BRONCHODILATOR
BUTOXAMINE
CARMOTEROL
CHEMBL:CHEMBL1160544
CHEMBL:CHEMBL116548
CHEMBL:CHEMBL1256364
CHEMBL:CHEMBL1257092
CHEMBL:CHEMBL1465049
CHEMBL:CHEMBL531322
CHEMBL:CHEMBL531401
CHEMBL:CHEMBL579725
CHEMBL:CHEMBL590927
CHEMBL:CHEMBL599896
CHEMBL:CHEMBL604311
CHF-6366
CLENBUTEROL HYDROCHLORIDE
CLOTRIMAZOLE A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.
COMPOUND 6 [PMID: 29769246]
DIENESTROL
FENOTEROL HBR
GLYCOPYRRONIUM BROMIDE
GSK159802
ICI118551
INDACATEROL MALEATE
ISOETHARINE HYDROCHLORIDE
ISOETHARINE MESYLATE
LAS190792
LEVALBUTEROL
LEVALBUTEROL HYDROCHLORIDE
LEVALBUTEROL TARTRATE
MEPOLIZUMAB
METAPROTERENOL A phenylethanolamine that has formula C11H17NO3.
METAPROTERENOL SULFATE
METHACHOLINE
MILVETEROL
NAVAFENTEROL
OLODATEROL A member of the class of benzoxazine that is 6-hydroxy-1,4-benzoxazin-3-one in which the hydrogen at position 4 is replaced by a (1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl group. Used (as its hydrochloride salt) for long-term treatment of airflow obstruction in patients with chronic obstructive pulmonary disease including chronic bronchitis and/or emphysema.
OLODATEROL HYDROCHLORIDE
PF-00610355
PIRBUTEROL
PIRBUTEROL ACETATE
PRILOCAINE HYDROCHLORIDE
PROCATEROL
PROCATEROL HYDROCHLORIDE
PW2101
RACEPINEPHRINE HYDROCHLORIDE
RACTOPAMINE A diastereoisomeric mixture of approximately equal amounts of all four possible diastereoisomers of 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol. A beta-adrenergic agonist, it is used (generally as the hydrochloride salt) as a feed additive for use in pigs and other livestock to promote protein deposition, resulting in leaner meat. The R,R diastereoisomer, butopamine, is responsible for most of the leanness-enhancing effects. While use of ractopamine has been banned in over 120 countries including throughout the EU, in the US it used in an estimated 80% of all beef, pork and turkey production.
REPROTEROL
RIMITEROL
RITODRINE
RITODRINE HYDROCHLORIDE
ROLIPRAM
SALMETEROL XINAFOATE
TERBUTALINE SULFATE
TIOTROPIUM
TULOBUTEROL
VILANTEROL An dichlorobenzene derivative that is used in the form of its trifenate salt for treatment of chronic obstructive pulmonary disease.
VILANTEROL .ALPHA.-PHENYL CINNAMATE
VILANTEROL TRIFENATATE
ZENIDOLOL
ZINTEROL
ZN2+
[3H]DIHYDROALPRENOLOL
AMIBEGRON
AMIBEGRON HYDROCHLORIDE
ARUNDIC ACID
BITOLTEROL
BOPINDOLOL
CL316243
L 755507
L-748328
L-748337
L742791
LY-377604
MN-246
NIPRADILOL
RAFABEGRON
RITOBEGRON
TALIBEGRON HYDROCHLORIDE
TRIHEXYPHENIDYL
VIBEGRON
[3H]L748337
BORTEZOMIB
BORTEZOMIB D-MANNITOL
CARFILZOMIB
IXAZOMIB
IXAZOMIB CITRATE
OPROZOMIB
ALANOSINE
BACILLUS CALMETTE-GUERIN ANTIGEN
BROXURIDINE
DACTINOMYCIN
EPOETIN ALFA
MASOPROCOL
METHYLNITROSOUREA
MIFEPRISTONE
MM-093
POLYESTRADIOL PHOSPHATE
POLYETHYLENE GLYCOL 4000
RUTIN A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.
TEGAFUR-URACIL
YTTRIUM Y 90 TACATUZUMAB TETRAXETAN
ALAGEBRIUM CHLORIDE
AZELIRAGON
COBALAMIN A cobalt-corrinoid hexaamide that is cobalamin with the oxidation state of the central cobalt atom unspecified.
MITOGEN-ACTIVATED PROTEIN KINASE INHIBITOR
PYRIDOXAMINE A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2.
METRELEPTIN
ADENOVIRUS VECTOR
ANGIOGENESIS INHIBITOR
CHLORTHALIDONE An isoindole that has formula C14H11ClN2O4S.
CYT006-ANGQB
GSK-2586881
MESTRANOL
VALSARTAN
5-BUTYL-METHYL IMMIDAZOLE CARBOXYLATE 30
ANGIOTENSIN A
ANGIOTENSIN II
ANGIOTENSIN II ACETATE
ANGIOTENSIN III
ANGIOTENSIN IV
ANTISENSE OLIGONUCLEOTIDES
ASCORBIC ACID
AZILSARTAN KAMEDOXOMIL
AZILSARTAN MEDOXOMIL A carboxylic ester obtained by formal condensation of the carboxy group of azilsartan with the hydroxy group of 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one. A prodrug for azilsartan, it is used for treatment of hypertension.
C-FOS ANTISENSE
CANDESARTAN CILEXETIL A biphenyl that has formula C33H34N6O6.
CHEMBL:CHEMBL125044
CHEMBL:CHEMBL1390716
CHEMBL:CHEMBL1445650
CHEMBL:CHEMBL1492017
CHEMBL:CHEMBL1972216
CHEMBL:CHEMBL2094484
CHEMBL:CHEMBL261693
CHEMBL:CHEMBL400912
CHEMBL:CHEMBL421088
CHEMBL:CHEMBL528694
CHEMBL:CHEMBL586135
CHEMBL:CHEMBL591834
CL-329167
COMPOUND 1 [PMID: 28379944]
COMPOUND 2 [PMID: 28379944]
EPROSARTAN
EPROSARTAN MESYLATE
EXP3174
FIMASARTAN
FORASARTAN
GAMMA-INTERFERON
HELENALIN A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3aS,4S,4aR,7aR,8R,9aR stereoisomer).
IDOXIFENE
IRBESARTAN
IRBESARTAN HYDROCHLORIDE
L-162,313
L-163,101
LOSARTAN POTASSIUM
LY301875
LY303336
MUSCLE RELAXANT
N,N`-BIS-ALKYL BUTYLIMMIDAZOLE 12B
NITRENDIPINE
OLMESARTAN MEDOXOMIL
PRATOSARTAN
SAPRISARTAN
SARALASIN
SARALASIN ACETATE
SPARSENTAN
TASOSARTAN
THERAPEUTIC ANDROSTANOLONE
TRV-120027
TRV023
TRV026
TYROSINE KINASE INHIBITOR
[SAR1,ALA8]ANG-II
[SAR1,GLY4,GLY8]ANG-II
[SAR1,ILE4,ILE8]ANG-II
[SAR1,ILE8]ANG-II
ANGIOTENSIN-(1-7)
AZD4017
CGP42112
CHEMBL:CHEMBL157946
COMPOUND 21 [PMID: 22802221]
NOVOKININ
OLODANRIGAN
PD123319 An imidazopyridine consisting of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine having 4-(dimethylamino)-3-methylbenzyl, diphenylacetyl and carboxy and groups at positions 1, 5 and 6 respectively
PUROMYCIN An aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome.
RECOMBINANT FIBROBLAST GROWTH FACTOR 2
RECOMBINANT TRANSFORMING GROWTH FACTOR-BETA 1
ROSIGLITAZONE MALEATE
LUMASIRAN
NEDOSIRAN
3-DEAZAADENOSINE
1-NAPHTHYLISOTHIOCYANATE
2-CHLORO-5-NITRO-N-PHENYLBENZAMIDE
3-METHYLCHOLANTHRENE
ALDICARB The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active.
BENZO(K)FLUORANTHENE
BENZOFURAN
BENZO[B]FLUORANTHENE An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring.
BENZO[DEF]CHRYSENE
BETA-NAPHTHOFLAVONE An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
CARBARIL
CHEMBL:CHEMBL1873684
CHEMBL:CHEMBL295337
CHEMBL:CHEMBL329673
CHEMBL:CHEMBL538965
CHEMBL:CHEMBL541230
CHEMBL:CHEMBL57394
CHEMBL:CHEMBL597452
CHEMBL:CHEMBL70582
CHEMBL:CHEMBL77675
CHEMBL:CHEMBL84685
CHRYSENE An ortho-fused polycyclic arene found commonly in the coal tar.
CHRYSIN A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.
CLIOQUINOL
COLFORSIN
CSC
CYPRODINIL A member of the class of aminopyrimidine that is N-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens including Tapesia yallundae, Botrytis spp., Alternaria spp. and Rhynchospium secalis. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds, most aquatic organisms and earthworms, but is not considered toxic to honeybees.
DESMEDIPHAM
DESMETHOXYYANGONIN
DIBENZ[A,H]ANTHRACENE
DICHLON
DIFLUBENZURON A benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group.
DIMETHYL YELLOW
DIPHENYLUREA
EMODIN A member of the class of hydroxyanthraquinones that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
EZUTROMID
LEVOTHYROXINE
LINURON A member of the class of ureas that is N-methyl urea substituted by a methoxy group at position 1 and a 3,4-dichlorophenyl group at position 3.
METHABENZTHIAZURON
METHYLCELLULOSE
MICHLER'S KETONE
NAPHTHOQUINONE A polycyclic aromatic ketone metabolite of naphthalene.
NICLOSAMIDE
NITAZOXANIDE
PENTACHLOROPHENOL A chlorophenol that is phenol substituted by 5 chloro groups.
PHENAZOPYRIDINE HYDROCHLORIDE
PIPERINE A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum.
PYRAFLUFEN-ETHYL
QUESTIOMYCIN B
QUINALPHOS An organothiophosphate insecticide that has formula C12H15N2O3PS.
RESVERATROL
RIMSULFURON
ROMIPLOSTIM
SALICYLANILIDE
TAPINAROF
TCDD
THIABENDAZOLE A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium.
YANGONIN
ARRY-371797
AZD7624
BMS-582949
NEMIRALISIB
RALIMETINIB MESYLATE
TAK-715
CYCLOSERINE
DAUNORUBICINOL
AK198
CAFICRESTAT
EPALRESTAT A monocarboxylic acid that is 1,3-thiazolidine which is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group. It is an inhibitor of aldose reductase (which catalyses the conversion of glucose to sorbitol) and is used for the treatment of some diabetic complications, including neuropathy.
FIDARESTAT
GOVORESTAT
LIDORESTAT
LIDORESTAT ANHYDROUS
MANGIFERIN A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.
QR-333
RANIRESTAT
SORBINIL An azaspiro compound having a monofluoro-substituted chromane skeleton spiro-linked to an imidazolidinedione ring.
SULINDAC A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.
TECTORIGENIN
THERAPEUTIC GROWTH FACTOR
TOLRESTAT
URACIL
ZENARESTAT
ZOPOLRESTAT
GLYCYRRHETINIC ACID
OLEANOLIC ACID A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.
URSOLIC ACID A pentacyclic triterpenoid that has formula C30H48O3.
CHEMBL:CHEMBL447448
CHEMBL:CHEMBL449129
CHEMBL:CHEMBL562352
ESTRONE A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17.
URSODIOL
ANTI-ANDROGEN
ASP-9521
BACCHARIN
CHEMBL:CHEMBL1682200
CHEMBL:CHEMBL1682201
CHEMBL:CHEMBL1682202
COMPOUND 1 [LOLLI ET AL., 2019]
EXEMESTANE A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer.
FLUFENAMIC ACID
KV-37
NONSTEROIDAL ANTIINFLAMMATORY DRUG
RJG-2051
TESTOSTERONE An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
THERAPEUTIC ANDROGEN
TOLFENAMIC ACID
FINASTERIDE An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.
(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
5-METHOXYCANTHINONE
A-674563
AFATINIB A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer.
AFURESERTIB
AFURESERTIB HYDROCHLORIDE
AKT INHIBITOR MK2206
ANDROGRAPHOLIDE A labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata that exhibits anti-HIV, anti-inflammatory and antineoplastic properties.
ARCHEXIN
BARDOXOLONE METHYL
BAY-1125976
BAY1125976
BMS-754807
CANERTINIB DIHYDROCHLORIDE
CANTHIN-6-ONE
CAPIVASERTIB
CHEMBL:CHEMBL1086397
CHEMBL:CHEMBL257158
CHEMBL:CHEMBL480356
CI-1040
CMX-2043
COMPOUND 1 [PMID: 20005102]
COMPOUND E22 [PMID: 31298542]
DABRAFENIB An organofluorine compound and antineoplastic agent, used as its mesylate salt in treatment of metastatic melanoma.
ENZASTAURIN
EUPALININ A
EVEROLIMUS
FASUDIL
FEXAGRATINIB
FULVESTRANT
GAMBOGIC AMIDE
GEDATOLISIB
GIGANTOL
GSK269962A
GSK690693
HU7691
IPATASERTIB
LAUROGUADINE
LY-2780301
LY-294002
M-2698
MIRANSERTIB
MK-2201
MK-2206 An organic heterotricyclic compound that is [1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one substituted at positions 8 and 9 respectively by 4-(1-aminocyclobutyl)phenyl and phenyl groups.
MS15
NINTEDANIB ESYLATE
NTQ1062
OMIPALISIB
ORIDONIN
PERIFOSINE A phospholipid consisting of 1,1-dimethylpiperidinium-4-yl hydrogen phosphate in which the hydrogen is replaced by a stearyl (octadecyl) group.
PIFUSERTIB
SOTRASTAURIN
SR-13668
TAS0612
TRICIRIBINE A nucleoside analogue in which the nucleobase portion is a 1,4,5,6,8-pentaazaacenaphthylene ring system substituted with an amino group at position 3, and a methyl group at position 5 and is bound to the beta-D-ribofuranosyl moiety by an N(1)-glycosidic linkage.
TRICIRIBINE PHOSPHATE
UPROSERTIB
VAD-044
VEVORISERTIB
WITHAFERIN A A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity.
WORTMANNIN A delta-lactone that has formula C23H24O8.
XL-418
XL418
AZD8055
OSI-027
SAPANISERTIB
PHT-427
AKT INHIBITOR LY2780301
PAN-AKT KINASE INHIBITOR GSK690693
RUPITASERTIB
PORPHOBILINOGEN A dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively.
ETHAMBUTOL HYDROCHLORIDE
ISONIAZID / PYRAZINAMIDE / RIFAMPIN
ALBUMIN HUMAN-KJDA
BISMUTH
CHEMBL:CHEMBL1630
CHEMBL:CHEMBL1945287
COCHINCHINENIN C
EBSELEN A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
EPICATECHIN
EPICATECHIN GALLATE
EPIGALLOCATECHIN
EVANS BLUE
FLUCONAZOLE A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It has been shown to exhibit antifungal activity.
GADOBENATE DIMEGLUMINE
GADOFOSVESET TRISODIUM
IODIPAMIDE
OXYPHENBUTAZONE
PHENYLBUTAZONE A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
PYROGALLOL A benzenetriol carrying hydroxy groups at positions 1, 2 and 3.
RALTITREXED
SODIUM DODECYL SULFATE An alkyl sulfate that has formula C12H25NaO4S.
WARFARIN A hydroxycoumarin that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.
[19F]-HALOPERIDOL
PRALUZATAMAB RAVTANSINE
(+)-WAY 100135
1,2-NAPHTHOQUINONE A naphthoquinone that has formula C10H6O2.
1,4-DIMETHOXYANTHRAQUINONE
2,3,4-TRIHYDROXY-4'-ETHOXYBENZOPHENONE
2,4-HEXADIENAL A fatty aldehyde that has formula C6H8O.
2-AMINOANTHRACENE
2-ARACHIDONOYLGLYCEROL An endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol.
2-ETHOXYCARBONYL-2-ETHOXYOXALOYLOXYDIHYDROCHRYSIN DIMETHYL ETHER
2-IODOACETAMIDE
2-MERCAPTOBENZOTHIAZOLE
2-METHYL-5,7,8-TRIMETHOXYISOFLAVONE
2-NITROANISOLE A member of the class of 2-nitroanisoles that is anisole in which one of the hydrogens ortho to the methoxy group is replaced by a nitro group.
2-PHENYLPHENOL
3,4-DIDESMETHYL-5-DESHYDROXY-3'-ETHOXYSCLEROIN
3,4-DIMETHOXYBENZALDEHYDE
3,5-DIIODO-L-TYROSINE A diiodotyrosine that is L-tyrosine carrying iodo-substituents at positions C-3 and C-5 of the benzyl group. It is an intermediate in the thyroid hormone synthesis.
3-METHOXYCATECHOL
4'-METHOXYCHALCONE
4-CHLOROMERCURIBENZOIC ACID
4-METHOXYDALBERGIONE
4-NONYLPHENOL A member of the class of phenols that is phenol which is para-substituted with a nonyl group.
5,7-DIHYDROXYISOFLAVONE
5-DEMETHYLNOBILETIN
5-HYDROXYTRYPTOPHAN
5-METHOXYISATIN
5-METHOXYPSORALEN
7,8-DIHYDROXYFLAVONE
ACETOCHLOR A monocarboxylic acid amide that is N-phenylacetamide carrying an ethyl and a methyl group at positions 2 and 6 respectively on the benzene ring while one of the methyl hydrogens as well as the hydrogen attached to the nitrogen atom have been replaced by a chloro and an ethoxymethyl group respectively.
ACID BLUE 129
ACROLEIN An enal that is prop-2-ene with an oxo group at position 1.
AG 112
AG 9
AG879
ALL-TRANS-RETINAL
ALLITRIDIN
ALPHA-CYPERMETHRIN
AM-630
AMBUNOL
ANANDAMIDE A fatty amide obtained by the formal condensation of arachidonic acid with ethanolamine.
ANISALDEHYDE
ANTHRALIN
ARACHIDONIC ACID A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
ARACHIDONYL TRIFLUOROMETHYL KETONE
ARTEMISININ
AVOCADYNE ACETATE
AZEPANE
BAICALEIN A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
BAY 11-7082
BAY-11-7085
BENSERAZIDE HYDROCHLORIDE
BENZALDEHYDE
BENZOPHENONE
BENZOTHIAZYL DISULFIDE
BENZYL ISOTHIOCYANATE An isothiocyanate that has formula C8H7NS.
BENZYLACETONE
BIFONAZOLE
BINOSPIRONE
BIS(2-ETHYLHEXYL) PHTHALATE
BIS(DIMETHYLAMINETHIOCARBONYL)MONOSULFIDE
BITHIONOL Diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
BRL50481
BROMOENOL LACTONE
BUSPIRONE An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the nitrogen atom.
BUSPIRONE HYDROCHLORIDE
BUTANAL A member of the class of butanals that consists of propane bearing a formyl substituent at the 1-position. The parent of the class of butanals.
CADMIUM ACETATE
CADMIUM DICHLORIDE
CAMPHOR OIL
CANDIDIN
CAPSAZEPINE A benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist.
CAPTAN A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.
CARBIDOPA ANHYDROUS
CARMINE
CARMUSTINE
CARNOSIC ACID
CATECHIN
CATECHOL A benzenediol comprising of a benzene core carrying two hydroxy substituents ortho to each other.
CHEMBL:CHEMBL1079460
CHEMBL:CHEMBL108851
CHEMBL:CHEMBL1091971
CHEMBL:CHEMBL113897
CHEMBL:CHEMBL120806
CHEMBL:CHEMBL1214274
CHEMBL:CHEMBL1222317
CHEMBL:CHEMBL1255936
CHEMBL:CHEMBL1256291
CHEMBL:CHEMBL126804
CHEMBL:CHEMBL1269845
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CHEMBL:CHEMBL1326758
CHEMBL:CHEMBL1332182
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CHEMBL:CHEMBL1363249
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CHEMBL:CHEMBL1392244
CHEMBL:CHEMBL139935
CHEMBL:CHEMBL1401091
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CHEMBL:CHEMBL1415851
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CHEMBL:CHEMBL1442783
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CHEMBL:CHEMBL1459280
CHEMBL:CHEMBL1486366
CHEMBL:CHEMBL1489812
CHEMBL:CHEMBL1498652
CHEMBL:CHEMBL151797
CHEMBL:CHEMBL1526167
CHEMBL:CHEMBL154580
CHEMBL:CHEMBL1549738
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CHEMBL:CHEMBL166486
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CHEMBL:CHEMBL17201
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CHEMBL:CHEMBL222556
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CHEMBL:CHEMBL244707
CHEMBL:CHEMBL24983
CHEMBL:CHEMBL259784
CHEMBL:CHEMBL26886
CHEMBL:CHEMBL271023
CHEMBL:CHEMBL275260
CHEMBL:CHEMBL312487
CHEMBL:CHEMBL313737
CHEMBL:CHEMBL316796
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CHEMBL:CHEMBL548540
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CHEMBL:CHEMBL576353
CHEMBL:CHEMBL576412
CHEMBL:CHEMBL577660
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CHEMBL:CHEMBL579028
CHEMBL:CHEMBL580421
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CHEMBL:CHEMBL581869
CHEMBL:CHEMBL581872
CHEMBL:CHEMBL585417
CHEMBL:CHEMBL585628
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CHEMBL:CHEMBL587772
CHEMBL:CHEMBL589207
CHEMBL:CHEMBL589469
CHEMBL:CHEMBL590660
CHEMBL:CHEMBL590949
CHEMBL:CHEMBL591137
CHEMBL:CHEMBL59150
CHEMBL:CHEMBL591628
CHEMBL:CHEMBL592106
CHEMBL:CHEMBL592124
CHEMBL:CHEMBL595227
CHEMBL:CHEMBL596847
CHEMBL:CHEMBL597449
CHEMBL:CHEMBL600342
CHEMBL:CHEMBL600908
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CHEMBL:CHEMBL601192
CHEMBL:CHEMBL601618
CHEMBL:CHEMBL601952
CHEMBL:CHEMBL601994
CHEMBL:CHEMBL602158
CHEMBL:CHEMBL602776
CHEMBL:CHEMBL602807
CHEMBL:CHEMBL602990
CHEMBL:CHEMBL603031
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CHEMBL:CHEMBL609030
CHEMBL:CHEMBL77387
CHEMBL:CHEMBL80155
CHEMBL:CHEMBL97858
CHLORAMPHENICOL An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions.
CHLORANIL
CHRYSOPHANOL
CILOSTAZOL A lactam that is 3,4-dihydroquinolin-2(1H)-one in which the hydrogen at position 6 is substiuted by a 4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy group.
CINNAMALDEHYDE The E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes.
CITRATE
CONGO RED FREE ACID
CRYPTOTANSHINONE
DAMNACANTHAL
DEPHOSTATIN
DIALLYLDISULFIDE
DICUMAROL
DIMERCAPROL
DISULFOTON An organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate.
DITHIOLETHIONE
DOCEBENONE
DOCONEXENT
DOMIPHEN BROMIDE
DOXEPIN HYDROCHLORIDE
DYCLONINE N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.
DYCLONINE HYDROCHLORIDE
E1501
E319
E927A
EDARAVONE
EMBELIN A hydroxybenzoquinone that is 1,4-benzoquinone substituted by hydroxy groups at positions 2 and 5 and an undecyl group at position 3. Isolated from, Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
EMODIC ACID
ETHACRYNIC ACID
ETHYL VANILLIN
EUGENOL
FENRETINIDE
FUMARPROTOCETRARIC ACID
FUROXAN
GALLIC ACID A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
GARDENIN
GARDENIN B
GILRETINOL ACETATE
GOSSYPETIN A hexahydroxyflavone having the hydroxy groups placed at the 3-, 3'-, 4'-, 5- 7- and 8-positions.
GUTHION
H-89
HAEMATOXYLIN
HARMINE A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7.
HEMICHOLINIUM-3
HOMOVANILLIC ACID A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
HYDRAZOBENZENE
INAMRINONE
IODOFORM
IRIGENOL
ISOTHYMONIN
JUGLONE A naphthoquinone that has formula C10H6O3.
KAINIC ACID A pyrrolidinecarboxylic acid that has formula C10H15NO4.
KAVAIN
KOPARIN
LAWSONE 1,4-Naphthoquinone carrying a hydroxy function at C-2. It is obtained from the leaves of Lawsonia inermis.
LEAD DIACETATE TRIHYDRATE
LINOLEIC ACID An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) steeochemistry.
LINOLENIC ACID Any of two trienoic essential fatty acids; a nutrient essential to the formation of prostaglandins. Also used in making paints and synthetic resins.
LIOTHYRONINE SODIUM
LUTEOLIN A 3'-hydroxyflavonoid which is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator.
MEDROXYPROGESTERONE ACETATE A steroid ester that has formula C24H34O4.
MERCAPTOPURINE A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6.
MERCURIC CHLORIDE
METHOXYCHLOR An organochlorine insecticide that has formula C16H15Cl3O2.
METHYL 7-DESHYDROXYPYROGALLIN-4-CARBOXYLATE
METHYL ISOBUTYL KETONE A ketone that has formula C6H12O.
METHYL PARATHIONE
METHYL ROBUSTONE
METHYLDOPA (RACEMIC)
METHYLENE BLUE An organic chloride salt that has formula C16H18N3S.Cl.
METHYLEPHEDRINE
METHYLERGONOVINE
METHYSERGIDE
METHYSTICIN A 2-pyranone that has formula C15H14O5.
METRONIDAZOLE A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
MG-132
MONASTROL A member of the class of thioureas that is 3,4-dihydropyrimidine-2(1)-thione substituted by a 3-hydroxyphenyl group at position 4, a methyl group at position 6 and a ethoxycarbonyl group at position 5.
MYRICETIN A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.
N- (9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE
N-DOCOSATETRA-7,10,13,16-ENOYLETHANOLAMINE
NADA
NAFAMOSTAT
NIFUROXAZIDE
NITROBENZENE A nitroarene consisting of benzene carrying a single nitro substituent. An industrial chemical used widely in the production of aniline.
NS-398 A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
OBTUSAQUINONE
OMEGA-CHLOROACETOPHENONE
ORTHOTOLIDINE
OSAJIN
OXYBENZONE A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.
OXYMETHOLONE
OXYTETRACYCLINE HYDROCHLORIDE
P-HYDROXYCINNAMALDEHYDE
PARATHION An organothiophosphate insecticide that has formula C10H14NO5PS.
PENTAERYTHRITOL TETRANITRATE A pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to those of glyceryl trinitrate, but with a more prolonged duration of action, and is used for treatment of angina pectoris. It is also one of the most powerful high explosives known and is a component of the plastic explosive known as Semtex.
PHENYL ISATIN
PHENYLGLYOXAL
PHENYLMERCURIC ACETATE
PHTHALIC ACID A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.
PIPERLONGUMINE
PIPERONYL BUTOXIDE A benzodioxole that has formula C19H30O5.
PIPOBROMAN
PIRINIXIC ACID An aryl sulfide that has formula C14H14ClN3O2S.
PLUMBAGIN A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively.
PROPACHLOR An anilide that consists of 2-chloroacetanilide bearing an N-isopropyl substituent.
PROPYLPARABEN
PROROXAN HYDROCHLORIDE
PROSTAGLANDIN A2 A prostaglandins A that has formula C20H30O4.
PURPUROGALLIN A cyclic ketone that is 5H-benzocycloheptene bearing an oxo group at position 5 and hydroxy groups at positions 2, 3, 4 and 6.
PYRITHIONE ZINC
PYRROLIDINE DITHIOCARBAMATE
PYRROLIDINE DITHIOCARBAMIC ACID, AMMONIUM SALT
R-(+)-METHANANDAMIDE
RABEPRAZOLE A sulfoxide that has formula C18H21N3O3S.
RALOXIFENE HYDROCHLORIDE
RIBAVIRIN A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. An inhibitor of HCV polymerase.
RO19-4603
ROFECOXIB
ROTTLERIN A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis.
SAPPANONE A DIMETHYL ETHER
SARCOLYSIN
SB 222200
SB-415286
SEMUSTINE An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group.
SODIUM AZIDE The sodium salt of hydrogen azide (hydrazoic acid).
SODIUM NITRITE
SP-600125
SULISOBENZONE
TAMOXIFEN CITRATE
TANSHINONE IIA
TETRANITROMETHANE An organonitrogen compound that has formula CN4O8.
THIMEROSAL An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.
THIOPHANATE METHYL
THIOTEPA
THIRAM
THYROXINE An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
TPCK
TRANSPLATIN A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
TYRPHOSTIN 23
TYRPHOSTIN 25
TYRPHOSTIN 47
TYRPHOSTIN A9
U73122
VALERENIC ACID
VANILLIN A member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively.
VANITIOLIDE
VITAMIN A A group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids. Vitamin A is involved in immune function, vision, reproduction, and cellular communication.
VITAMIN K3
Z-PRO-PROLINAL
ZAPA
ZAPRINAST
ZEARALENONE A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
ZIRAM A dithiocarbamate salt that is the zinc salt of dimethyldithiocarbamic acid. It is a broad-spectrum fungicide that is also used to accelerate the vulcanisation of rubber.
ZUCAPSAICIN
RETINOIC ACID AGENT
VITAMIN A COMPOUND
METHIONINE A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.
HEROIN
MIRIVADELGAT
NITROGLYCERIN A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
PRUNETIN A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group.
CHLORMERODRIN Urea in which one of the hydrogens is substituted by a 3-chloromercury-2-methoxyprop-1-yl group. It was formerly used as a diuretic, but more potent and less toxic drugs are now available. Its radiolabelled ((197)Hg, (203)Hg) forms were used in diagnostic aids in renal imaging and brain scans.
LEVETIRACETAM
PHENYTOIN SODIUM
SODIUM OXYBATE
SUCCINIC ACID
VALPROATE SODIUM
NM-702
PEFCALCITOL
ALECTINIB
ALECTINIB HYDROCHLORIDE
ALK INHIBITOR ASP3026
ALK INHIBITOR NVL-655
ALK INHIBITOR TAE684
ALK/C-MET INHIBITOR TQ-B3139
ALVOCIDIB
AP-26113
APG-2449
ASP-3026
ATEZOLIZUMAB
AZD3463
BATOPROTAFIB
BELIZATINIB
BEVACIZUMAB
BRENTUXIMAB VEDOTIN
BRIGATINIB
CARBAMAZEPINE A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
CEMIPLIMAB
CEP-37440
CHEMBL:CHEMBL4439276
COMPOUND 15 [PMID: 24900237]
COMPOUND 17 [PMID: 34176264]
COMPOUND 25B [PMID: 22564207]
COMPOUND 5G [PMID: 20483621]
COMPOUND 5M [PMID: 20483621]
COMPOUND 5N [PMID: 20483621]
COMPOUND 8E [PMID: 24432909]
CONTELTINIB
CPD-1224
CRENOLANIB
DINACICLIB
DIROZALKIB
DURVALUMAB
EG5 KINESIN-RELATED MOTOR PROTEIN INHIBITOR 4SC-205
ENSARTINIB
ENVONALKIB
FAM150B
FICONALKIB
FILGOTINIB
GANETESPIB
GILTERITINIB
GSK-1838705A
GW441756X
HJC0152
IDASANUTLIN
IPILIMUMAB
IRUPLINALKIB
LINIFANIB
LORLATINIB
LUMINESPIB
MTI-31
NAVITOCLAX
NELADALKIB
NIVOLUMAB
NVP-TAE 226
OCTREOTIDE ACETATE
ONALESPIB
P53/HDM2 INTERACTION INHIBITOR CGM097
PEMBROLIZUMAB
PF-07284892
PF-562271
PLB1003
RAMUCIRUMAB
RECOMBINANT INTERLEUKIN 10
REPOTRECTINIB
SELUMETINIB
TALETRECTINIB
TAMATINIB
TEMOZOLOMIDE
TEPOTINIB
THZ1
TL13-112
TREMELIMUMAB
UNECRITINIB
VINCRISTINE SULFATE
X-376
ZOLEDRONIC ACID ANHYDROUS
ZOTIZALKIB
BENOXAPROFEN A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group. It was used as a non-steroidal anti-inflammatory drug until 1982 when it was withdrawn from the market due to adverse side-effects including liver necrosis, photosensitivity, and carcinogenicity in animals.
CHEMBL:CHEMBL1164975
CHEMBL:CHEMBL261557
CHEMBL:CHEMBL528045
CHEMBL:CHEMBL580727
CHEMBL:CHEMBL68534
ETHOPROPAZINE HYDROCHLORIDE
FISETIN A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.
METAMIZOLE SODIUM
ML355
N,N'-DIPHENYL-P-PHENYLENEDIAMINE
PSEUDOCHELERYTHRINE
(+)-EPITAXIFOLIN
(+/-)-ERIODICTYOL
(S)-PROMETHAZINE
2-APB
4,4'-DIMETHOXYDALBERGIONE
AM404
APIOL
ATHRAQUINONES A
AURINTRICARBOXYLIC ACID
BISABOLOL
BITHIONOLATE SODIUM
CAFFEIC ACID PHENETHYL ESTER
CHAULMOOGRIC ACID, ETHYL ESTER
CHEMBL:CHEMBL1200765
CHEMBL:CHEMBL122701
CHEMBL:CHEMBL1481974
CHEMBL:CHEMBL1591531
CHEMBL:CHEMBL184450
CHEMBL:CHEMBL222993
CHEMBL:CHEMBL238624
CHEMBL:CHEMBL241813
CHEMBL:CHEMBL260342
CHEMBL:CHEMBL453797
CHEMBL:CHEMBL53898
CHEMBL:CHEMBL56393
CHEMBL:CHEMBL56731
CHEMBL:CHEMBL580851
CHEMBL:CHEMBL598663
CHEMBL:CHEMBL601528
CHEMBL:CHEMBL602213
CHEMBL:CHEMBL67535
CHEMBL:CHEMBL8328
CHOLECALCIFEROL
CITRONELLOL A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.
CITRONELLYL ACETATE
COMPOUND 34 [PMID: 20866075]
CUMENE HYDROPEROXIDE A peroxol that is cumene in which the alpha-hydrogen is replaced by a hydroperoxy group.
DALBERGIONE, 4-METHOXY-4'-HYDROXY-
DAPHNETIN
DEOXYVASICINONE
DICHLOROPHEN
DIHYDROGAMBOGIC ACID
DL-TRYPTOPHAN
E324
FENTICLOR
FRAXETIN A hydroxycoumarin that has formula C10H8O5.
GAVESTINEL SODIUM
GERALDOL
GERANIOL A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end.
GINGKOLIC ACID
GW5074
HEXACHLOROPHENE
HOMIDIUM BROMIDE
IRIGINOL HEXAACEATATE
LUFENURON
LY-255283
MK-886
ML351
N-ARACHIDONOYLGLYCINE Biologically active derivative of anandamide
N-OLEOYLDOPAMINE
NEROLIDOL
NONIVAMIDE
PD-146176
PKUMDL_MH_1001
POMIFERIN
PROCARBAZINE
PTAEROXYLIN
PURPURIN A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4.
QUINALIZARIN A tetrahydroxyanthraquinone having the four hydroxy groups at the 1-, 2-, 5- and 8-positions.
RELCOVAPTAN
RHEIN An anthracene that has formula C15H8O6.
SANGUINARINE SULFATE
SILVER SULFADIAZINE
TRICETIN Flavone hydroxylated at positions 3', 4', 5, 5' and 7.
U0126
VATIQUINONE
[3H]GBR12935
AHPN
CHELERYTHRINE A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
CHEMBL:CHEMBL1367933
CHEMBL:CHEMBL242171
CHEMBL:CHEMBL581044
CHEMBL:CHEMBL601616
COMPOUND 21N [PMID: 17656086]
DIHYDROXIDINE
GOSSYPOL A polyphenol that has formula C30H30O8.
HEXESTROL A stilbenoid that has formula C18H22O2.
HINOKITIOL
HYPERICIN A carbopolycyclic compound that has formula C30H16O8.
MLS000536924
PICEATANNOL A stilbenol that has formula C14H12O4.
PROTOPORPHYRIN
RHODOMYRTOXIN B
TROGLITAZONE
5-LOX ACTIVATING PROTEIN
5-LOX INHIBITOR 2M [PMID: 30199704]
5-OXO-ETE An oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds.
6BIO
ACACETIN
ANACARDIC ACID A hydroxybenzoic acid that has formula C22H36O3.
ATRELEUTON
BALSALAZIDE A monohydroxybenzoic acid consisting of 5-aminosalicylic acid (mesalazine) linked to 4-aminobenzoyl-beta-alanine via an azo bond.
BALSALAZIDE DISODIUM
BW B70C
CHEMBL:CHEMBL416038
CHEMBL:CHEMBL502496
CJ13610
DARBUFELONE
DIETHYLCARBAMAZINE
EMVODODSTAT
HONOKIOL A biphenyl that has formula C18H18O2.
LICOFELONE
MECLOFENAMATE
MECLOFENAMATE SODIUM
MESALAMINE A monohydroxybenzoic acid that is salicylic acid which is substituted by an amino group at the 5-position.
MILK THISTLE SEED EXTRACT
OLSALAZINE SODIUM
PF-04191834
PF-4191834
RILOPIROX
TENIDAP A thiophene that has formula C14H9ClN2O3S.
TEPOXALIN A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.
TIPELUKAST
ZILEUTON
FIBOFLAPON
FIBOFLAPON SODIUM
VELIFLAPON
AMIFOSTINE ANHYDROUS
CEPHALOCHROMIN
CHEMBL:CHEMBL1408276
CHEMBL:CHEMBL146710
CHEMBL:CHEMBL1731432
CHEMBL:CHEMBL2094652
CHEMBL:CHEMBL234338
CHEMBL:CHEMBL576409
CHEMBL:CHEMBL587759
CHEMBL:CHEMBL600360
CHEMBL:CHEMBL601543
DIHYDRODAPHNODORIN B
SULFURETIN
TERPYRIDINE
TIOXOLONE
ISOQUERCETIN
THUNBERGINOL B
ADALIMUMAB
ASFOTASE ALFA
CERTOLIZUMAB PEGOL
CHEMBL:CHEMBL1256783
CHEMBL:CHEMBL260311
CHEMBL:CHEMBL505807
CHEMBL:CHEMBL600956
CHEMBL:CHEMBL81782
ETANERCEPT
LEVAMISOLE
PYROGALLOL RED
BETA-ADRENERGIC ANTAGONIST
BIPHOSPHONATE
PREDNISOLONE A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
TROMETHAMINE
DIETHYLSTILBESTROL
THERAPEUTIC GONADOTROPIN
ROXITHROMYCIN
ACARBOSE A tetrasaccharide derivative consisting of a dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl C7 cyclitol moiety [called valienol (or valienamine)] linked via nitrogen to isomaltotriose.
LIPROTAMASE
AMG-780
ANTI-ANGIOPOIETIN MONOCLONAL ANTIBODY AMG 780
TREBANANIB
CVX-060
CVX-241
FARICIMAB
MEDI-3617
NESVACUMAB
RECOMBINANT VASCULAR ENDOTHELIAL GROWTH FACTOR
VANUCIZUMAB
ZANSECIMAB
EVINACUMAB
VUPANORSEN
ARIPIPRAZOLE LAUROXIL
NEMONAPRIDE A racemate composed of (2S,3S)- and (2R,3R)-enantiomers of nemonapride. Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.
9-ANTHROIC ACID An anthroic acid carrying the carboxy substituent at position 9.
ANI9
CA2+
CACCINH-A01
CROFELEMER
DCDPC
DIDS
EACT
INS(3,4,5,6)P4
MIBEFRADIL
MONNA
NIFLUMIC ACID
NPPB natriuretic peptide B|This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein&apos;s biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
PAM_16A
SITS
T16AINH-A01
TANNIC ACID
TMINH-23
AFLIBERCEPT
DULOXETINE HYDROCHLORIDE
RANIBIZUMAB
BETULINIC ACID A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties.
BTB07018
CEPHALOSPORIN ANTIBIOTIC
CNGRC PEPTIDE-TNF ALPHA CONJUGATE
COMPOUND 1A [PMID: 25692029]
COMPOUND I3 [PMID: 23428964]
GENTAMICIN
JFD00064
MITOFLAXONE
OPIORPHIN
PL37
RECOMBINANT INTERLEUKIN-13
RECOMBINANT TRANSFORMING GROWTH FACTOR
TOSEDOSTAT
TRIBUTYRIN A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by butyric acid.
UBENIMEX
ZINC CHLORIDE
ZINC SULFATE ANHYDROUS
ALCLOMETASONE A prednisolone compound having an alpha-chloro substituent at the 7-position and an alpha-methyl substituent at the 16-position.
AMCINONIDE A corticosteroid that has formula C28H35FO7.
BECLOMETHASONE A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively.
CLOBETASOL 16beta-Methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
CLOCORTOLONE
DESONIDE Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.
DESOXIMETASONE Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.
DIFLORASONE DIACETATE The 17,21-diacetate derivative of diflorasone. It is used topically for its anti-inflammatory and antipruritic properties in the treatment of various skin disorders.
FLUMETHASONE PIVALATE A pivalate ester that has formula C27H36F2O6.
HALOBETASOL
HYDROCORTAMATE A glycinyl ester that has formula C27H41NO6.
LOTEPREDNOL A steroid acid ester that has formula C21H27ClO5.
MOMETASONE A chlorinated steroid that has formula C22H28Cl2O4.
PREDNICARBATE
PURIFIED PROTEIN DERIVATIVE
RIMEXOLONE
ST 638
STAUROSPORINE An indolocarbazole alkaloid that has formula C28H26N4O3.
TRIAMCINOLONE A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections.
ANISTREPLASE
N-ETHYLMALEIMIDE A member of the class of maleimides that is the N-ethyl derivative of maleimide.
DIANEXIN
LAPACHONE
JZL195
PROXIBARBAL
MOFEGILINE
PHENELZINE
PXS-4681A
PXS-4728A
TIMOLUMAB
VEPALIMOMAB
ALLOPURINOL A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.
FEBUXOSTAT
ISOVANILLIN
9,10-PHENANTHRENEQUINONE
ALEXIDINE HYDROCHLORIDE
AMINODIMETHOXYQUINAZOLINYLPIPERAZINE
BENZETHONIUM CHLORIDE
CALANOLIDE A
CALMIDAZOLIUM CHLORIDE
CEFIXIME ANHYDROUS
CHEMBL:CHEMBL1098875
CHEMBL:CHEMBL1321398
CHEMBL:CHEMBL1481509
CHEMBL:CHEMBL1576310
CHEMBL:CHEMBL1989853
CHEMBL:CHEMBL299853
CHEMBL:CHEMBL527336
CHEMBL:CHEMBL578944
CHEMBL:CHEMBL581868
CHEMBL:CHEMBL582722
CHEMBL:CHEMBL584626
CHEMBL:CHEMBL585656
CHEMBL:CHEMBL590691
CHEMBL:CHEMBL592115
CHEMBL:CHEMBL599924
CHEMBL:CHEMBL600175
CHEMBL:CHEMBL600313
CHEMBL:CHEMBL600336
CHEMBL:CHEMBL601757
CHEMBL:CHEMBL86464
FLUPIRTINE MALEATE
METHYLENE BLUE ANHYDROUS
PYRONIN Y
ROEMERINE
SCOULERINE
THONZONIUM BROMIDE
CHEMBL:CHEMBL1372046
CHEMBL:CHEMBL274921
CHEMBL:CHEMBL297304
CHEMBL:CHEMBL484640
CHEMBL:CHEMBL546649
HESPERIDIN A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
SLAZINIC ACID
CLOFARABINE
RNR INHIBITOR COH29
TRIMETHOPRIM/SULFADOXINE
ABIRATERONE ACETATE
BASROPARIB
BINIMETINIB
BUPARLISIB
CHEMBL:CHEMBL1086580
CHEMBL:CHEMBL3753077
DECITABINE
EFLORNITHINE
ENZALUTAMIDE
ICG-001
NIROGACESTAT
OSUGACESTAT
PYRVINIUM
TETMYB DNA VACCINE
VANTICTUMAB
VINORELBINE A vinca alkaloid with a norvinblastine skeleton.
DEZAMIZUMAB
MIRIDESAP
ARI-3099
3,4-DIHYDROXYPHENYLACETIC ACID
6-HYDROXYMELATONIN A member of the class of tryptamines that is melatonin with a hydroxy group substituent at position 6.
7NI
ACRIFLAVINE HYDROCHLORIDE
ALTENUSIN
AMPICILLIN (ANHYDROUS)
AMPICILLIN TRIHYDRATE
APX-3330
ASCORBYL PALMITATE
ASTERRIC ACID
AVOBENZONE
BENZOQUINONE
CARBOPLATINE
CARMINIC ACID
CARUBICIN
CEFAMANDOLE SODIUM
CEFOTAXIME SODIUM
CEPHALORIDINE
CEPHAPIRIN SODIUM
CHEMBL:CHEMBL124006
CHEMBL:CHEMBL1255647
CHEMBL:CHEMBL1256813
CHEMBL:CHEMBL1305393
CHEMBL:CHEMBL136344
CHEMBL:CHEMBL1451216
CHEMBL:CHEMBL1601846
CHEMBL:CHEMBL175266
CHEMBL:CHEMBL177756
CHEMBL:CHEMBL179611
CHEMBL:CHEMBL19954
CHEMBL:CHEMBL211670
CHEMBL:CHEMBL515252
CHEMBL:CHEMBL578741
CHEMBL:CHEMBL599013
CYCLOBENZAPRINE HYDROCHLORIDE
DCMU
DEXPROPRANOLOL HYDROCHLORIDE
DIENOCHLOR An organochlorine compound that has formula C10Cl10.
EICOSATETRANOIC ACID
ELLAGIC ACID An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.
ELLIPTECINE
EQUILIN A 17-oxo steroid that has formula C18H20O2.
ERBSTATIN
ERYTHROSINE
EUFLAVINE
EUPAFOLIN
GALLIC ACID METHYL ESTER
HEMATOXYLIN
HISPIDIN Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).
HYCANTHONE A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
IMIPRAMINE HYDROCHLORIDE
INDAPAMIDE
INDIGO
IOFETAMINE HYDROCHLORIDE
IRETOL
ISOKAEMPFERIDE
ISOSPAGLUMIC ACID
L-CCG-I
L-NOREPINEPHRINE
LY367385
METHACYCLINE HYDROCHLORIDE
METHANESULFONIC ACID METHYL ESTER
MINOCYCLINE HYDROCHLORIDE
MITOXANTRONE HYDROCHLORIDE
MUNDULONE ACETATE
NBQX
NIMESULIDE
NORDEFRIN
OLTIPRAZ A 1,2-dithiole that is 3H-1,2-dithiole-3-thione substituted at positions 4 and 5 by methyl and pyrazin-2-yl groups respectively.
OXIDOPAMINE A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
OXIDOPAMINE HYDROCHLORIDE
OXYTETRACYCLINE ANHYDROUS
PERSEITOL
POTASSIUM DICHROMATE A potassium salt that is the dipotassium salt of dichromic acid.
PROPANTHELINE BROMIDE
PROPAZINE A diamino-1,3,5-triazine that is N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.
PROPIDIUM A phenanthridine that has formula C27H34N4.
PROTOPORPHYRIN DISODIUM
QUERCETIN DIHYDRATE
QUINACRINE DIHYDROCHLORIDE
ROBINETIN A flavone that has formula C15H10O7.
ROSE BENGAL
ROSMARINIC ACID The 1-carboxy-2-(2,4-dihydroxyphenyl)ethyl ester of trans-caffeic acid.
SB 216763
SENNOSIDE A
SENNOSIDE B
SHIKONIN A naphthoquinone that has formula C16H16O5.
STICTIC ACID
SULOCHRIN
SURAMIN
SURAMIN HEXASODIUM
TETRAIDOFLUORESCEIN
TETROQUINONE
THIOCTIC ACID
THIOLACTOMYCIN
VITEXIN
WEDELOLACTONE A member of the class of coumestans that is coumestan with hydroxy substituents as positions 1, 8 and 9 and a methoxy substituent at position 3.
AVAGACESTAT
BEGACESTAT
CHEMBL:CHEMBL392068
GSI-136
IC261
METHYLINOSITOL
MK-0752
NIROGACESTAT HYDROBROMIDE
NOTCH SIGNALING PATHWAY INHIBITOR MK0752
RG-4733
SEMAGACESTAT
TARENFLURBIL
CYCLOOXYGENASE INHIBITOR
ALX40-4C
APELIN
APELIN RECEPTOR EARLY ENDOGENOUS LIGAND
APELIN-13
APELIN-17
APELIN-36
APT-101
AZELAPRAG
BMS-986224
CMF-019
COMPOUND 1 [PMID: 25241924]
COMPOUND 14A [PMID: 34795866]
COMPOUND 15A
COMPOUND 21 [PMID: 34855405]
COMPOUND 35 [PMID: 41114343]
COMPOUND 39 [PMID: 34982553]
COMPOUND 40 [PMID: 34982553]
CYCLO APELIN-12 (1-12)
CYCLO APELIN-12 (7-12)
CYCLOUREA APELIN-12 (1-7)
E339-3D6
ELABELA/TODDLER-11
ELABELA/TODDLER-21
ELABELA/TODDLER-32
ML221
ML233
MM07
MM54
[125I](PYR1)APELIN-13
[125I]APELIN-13
[125I][GLP65NLE75,TYR77]APELIN-13
[125I][NLE75,TYR77]APELIN-36 (HUMAN)
[3H](PYR1)[MET(0)11]-APELIN-13
[PYR1]APELIN-13
APABETALONE
BMS309403
CER-001
GENERIC DRUG
PROGESTIN A synthetic progestogen.
PROTEIN PHOSPHATASE INHIBITOR
PROTEIN SYNTHESIS INHIBITOR
PEGASPARGASE
CHOLESTYRAMINE RESIN
D-ALPHA-TOCOPHEROL
EDOXABAN
HEPARIN A highly sulfated linear glycosaminoglycan comprising complex patterns of uronic acid-(1->4)-D-glucosamine repeating subunits. Used as an injectable anticoagulant, it has the highest negative charge density of any known biological molecule.
INCLISIRAN
LOMITAPIDE MESYLATE
MIPOMERSEN
PITAVASTATIN
REVERSE TRANSCRIPTASE INHIBITOR
RIVAROXABAN
TRIFLUOPERAZINE HYDROCHLORIDE
CEFOTETAN A semi-synthetic cephalosporin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of beta-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms.
CHEMBL:CHEMBL1388703
CHEMBL:CHEMBL582287
CHEMBL:CHEMBL584514
CHEMBL:CHEMBL586670
CHEMBL:CHEMBL589421
CHEMBL:CHEMBL589711
CHEMBL:CHEMBL590706
CHEMBL:CHEMBL592314
CHEMBL:CHEMBL600306
CHEMBL:CHEMBL600692
CHEMBL:CHEMBL601744
DIMETHYLPHENYLPIPERAZINIUM IODIDE
GLAUCINE METHIODIDE
STILONIUM IODIDE
(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
2,3,4,4'-TETRAMETHOXYBIPHENYL
CHEMBL:CHEMBL103583
CHEMBL:CHEMBL1287981
CHEMBL:CHEMBL1451921
CHEMBL:CHEMBL1504679
CHEMBL:CHEMBL1520346
CHEMBL:CHEMBL192626
CHEMBL:CHEMBL219416
CHEMBL:CHEMBL277148
CHEMBL:CHEMBL578504
CHEMBL:CHEMBL582675
CHEMBL:CHEMBL584442
CHEMBL:CHEMBL584635
CHEMBL:CHEMBL584849
CHEMBL:CHEMBL584868
CHEMBL:CHEMBL585240
CHEMBL:CHEMBL590672
CHEMBL:CHEMBL591148
CHEMBL:CHEMBL601550
CHEMBL:CHEMBL602759
CHEMBL:CHEMBL609438
CHEMBL:CHEMBL609606
SEMAXANIB
APOMORPHINE HYDROCHLORIDE
CHEMBL:CHEMBL118678
CHEMBL:CHEMBL122355
CHEMBL:CHEMBL1255944
CHEMBL:CHEMBL410484
CHEMBL:CHEMBL428064
PROTOAPIGENONE
VOLANESORSEN
ACE INHIBITOR
ADUCANUMAB
AEM-28
BENZO(A)PYRENE-7,8-DIOL 9,10-EPOXIDE
CHOLESTEROL
CN-105
DONANEMAB
FAT EMULSION
IMMUNOSUPPRESSANT
LECANEMAB
LORAZEPAM
LUTEIN A carotenol that has formula C40H56O2.
NORETHINDRONE ACETATE
PHYTOSTEROL
SOY PROTEIN ISOLATE
2-CHLOROADENOSINE-5-TRIPHOSPHATE
3,5-DICAFFEOYLQUINIC ACID
AMILOMOTIDE
AMPHOTERICIN B LIPOSOMAL
BAPINEUZUMAB
CAPROSPINOL
CHEMBL:CHEMBL177126
CHEMBL:CHEMBL477841
CRENEZUMAB
FERULATE
FLORBETAPIR F-18
GANTENERUMAB
GENTIAN VIOLET CATION
GSK933776
HYDROXYCHLOROQUINE
INOSITOL Any cyclohexane-1,2,3,4,5,6-hexol.
ISOCHLOROGENIC ACID B
PARAROSANILINE An iminie that is 4-methylidenecyclohexa-2,5-dien-1-imine in which both the hydrogens of the methylidene group are replaced by 4-aminophenyl groups.
PONEZUMAB
PRADEMAGENE ZAMIKERACEL
PROPOFOL A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
PTI-110
SCYLLITOL
SOLANEZUMAB
T-817 MALEATE
TRAMIPROSATE
TRIAZINATE
VALILTRAMIPROSATE
VANUTIDE CRIDIFICAR
5-HYDROXYMETHYL-2-FURFURAL
ACETAZOLAMIDE A thiadiazole that has formula C4H6N4O3S2.
AG+
CARBONIC ANHYDRASE INHIBITOR
COLLAGENASE CLOSTRIDIUM HISTOLYTICUM
COMPOUND 1 [PMID: 23113556]
HG2+
PCMBS
REMLARSEN
AUDIEN
AUPHEN
ACETYLSULFANILAMIDE
ECULIZUMAB
ETHOXZOLAMIDE 1,3-Benzothiazole substituted a sulfonamide and an ethoxy group at positions 2 and 6, respectively. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
INEBILIZUMAB
LAMOTRIGINE A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.
RAVULIZUMAB
SATRALIZUMAB
SUMATRIPTAN A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family).
ZONISAMIDE A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
FLUTAMIDE A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
PHLORETIN A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.
UREA A carbonyl group with two C-bound amine groups.
(2-NITROVINYL)BENZENE
(R)-BICALUTAMIDE
17&ALPHA;-ESTRADIOL
17-ALPHA-HYDROXYPROGESTERONE
2,4-DINITROPHENOL A dinitrophenol having the nitro groups at the 2- and 4-positions.
2-ACETYLAMINOFLUORENE
2-MERCAPTOBENZIMIDAZOLE
3,3',4',5-TETRACHLOROSALICYLANILIDE A salicylanilide derivative with chloride substituents at C-3 and C-5 of the salicylate moiety and at C-3 and C-4 of the anilide moiety.
4'-DEMETHYLEPIPODOPHYLLOTOXIN
4-AMINOPHENOL An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.
4-NITROANILINE A nitroaniline carrying a nitro group at position 4.
ABAMECTIN Mixture of 80% avermectin B1a and 20% avermectin B1b.
ACETOPHENAZINE
ACIVICIN An L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl group. A glutamine analogue antimetabolite, it interferes with glutamate metabolism and several glutamate-dependent synthetic enzymes. It is obtained as a fermentation product of Streptomyces sviceus bacteria.
ACLARUBICIN
AFLOQUALONE
ALACHLOR An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.
ALCLOFENAC An aromatic ether in which the ether oxygen links an allyl group to the 4-position of (3-chlorophenyl)acetic acid.A non-steroidal anti-inflammatory drug, it was withdrawn from the UK market in 1979 due to concerns with its association with vasculitis and rash.
ALCLOMETASONE DIPROPIONATE A prednisolone compound having an alpha-chloro substituent at the 7-position, an alpha-methyl substituent at the 16-position and O-propanoyl groups at the 17- and 21-positions.
ALDOSTERONE A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
ALEXIDINE DIHYDROCHLORIDE
ALFAXALONE
ALLANTOIN An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen.
ALLETHRIN
ALLISAN
ALPHA-TERTHIENYL
ALTRENOGEST
AMBAZONE
AMDINOCILLIN
AMI-1
AMLEXANOX
AMOROLFINE
AMPEROZIDE HYDROCHLORIDE
AMPIROXICAM
AMSACRINE HYDROCHLORIDE
ANDARINE
ANDROGEN RECEPTOR ANTAGONIST ONC1-0013B
ANDROGEN RECEPTOR ANTAGONIST TAS3681
ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDE AZD5312
ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDE EZN-4176
ANDROSTENEDIOL
ANDROSTENEDIONE
ANECORTAVE ACETATE
ANETHOLTRITHION
APALUTAMIDE
APC-100
APLAVIROC HYDROCHLORIDE
APRINDINE HYDROCHLORIDE
ARANIDIPINE
ARD-266
ARD-69
ASTEMIZOLE
ATALUREN
ATRACURIUM BESYLATE
ATROPINE METHYLBROMIDE
AZAMETHIPHOS An organochlorine acaricide that has formula C9H10ClN2O5PS.
AZARIBINE
AZASERINE
AZD3514
AZELNIDIPINE
AZINPHOS-ETHYL
AZOXYSTROBIN An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.
BATILOL
BENFLUOREX HYDROCHLORIDE
BENFURACARB A 1-benzofuran that has formula C20H30N2O5S.
BENORILATE
BENOXACOR
BENSULIDE A benzene that has formula C14H24NO4PS3.
BENZODODECINIUM CHLORIDE
BENZOXIQUINE
BETAMETHASONE BUTYRATE PROPIONATE
BETAMETHASONE DIPROPIONATE
BETAMETHASONE SODIUM PHOSPHATE
BETAMETHASONE VALERATE A steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester.
BIAPENEM
BICALUTAMIDE A sulfone that is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism.
BIFENAZATE
BIFENOX
BIOALLETHRIN S-CYCLOPENTENYL ISOMER
BIS(PIPERIDINYLTHIOCARBONYL)DISULFIDE
BISACODYL
BISPHENOL A A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
BROMEBRIC ACID
BROMOCRESOL GREEN
BROMOXYNIL
BROMUCONAZOLE
BROQUINALDOL
BROTIZOLAM
BRUCINE A monoterpenoid indole alkaloid that has formula C23H26N2O4.
BUFOGENIN A steroid lactone that has formula C24H32O4.
BUNAMIDINE HYDROCHLORIDE
BUPIRIMATE A member of the class of aminopyrimidines that is 2-ethylaminopyrimidine carrying methyl, butyl and dimethylaminosulfooxy substituents at posiitons 4, 5 and 6 respectively.
BUPRENORPHINE HYDROCHLORIDE
BUTACHLOR An anilide that has formula C17H26ClNO2.
BUTACLAMOL HYDROCHLORIDE
BUTAMBEN
BUTONATE
CALCIFEDIOL ANHYDROUS
CALCIPOTRIENE
CALCITRIOL A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
CALCIUM PANTOTHENATE
CAMBENDAZOLE
CANNABINOL
CANRENOATE POTASSIUM
CANRENONE
CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE
CARBOQUONE
CARBOSULFAN A 1-benzofuran that has formula C20H32N2O3S.
CEFONICID SODIUM
CEFPODOXIME PROXETIL
CERIVASTATIN SODIUM
CETALKONIUM CHLORIDE
CETRIMONIUM BROMIDE
CETYLPYRIDINIUM BROMIDE
CHEMBL:CHEMBL1047
CHEMBL:CHEMBL109747
CHEMBL:CHEMBL109873
CHEMBL:CHEMBL1099140
CHEMBL:CHEMBL1180003
CHEMBL:CHEMBL118280
CHEMBL:CHEMBL1231723
CHEMBL:CHEMBL1235854
CHEMBL:CHEMBL135115
CHEMBL:CHEMBL1436543
CHEMBL:CHEMBL1474
CHEMBL:CHEMBL1521156
CHEMBL:CHEMBL1606
CHEMBL:CHEMBL168075
CHEMBL:CHEMBL1738936
CHEMBL:CHEMBL1738937
CHEMBL:CHEMBL1784521
CHEMBL:CHEMBL1923999
CHEMBL:CHEMBL1946013
CHEMBL:CHEMBL1946014
CHEMBL:CHEMBL1946449
CHEMBL:CHEMBL194881
CHEMBL:CHEMBL2059711
CHEMBL:CHEMBL2164761
CHEMBL:CHEMBL224318
CHEMBL:CHEMBL225563
CHEMBL:CHEMBL229264
CHEMBL:CHEMBL259327
CHEMBL:CHEMBL306147
CHEMBL:CHEMBL332670
CHEMBL:CHEMBL333177
CHEMBL:CHEMBL34833
CHEMBL:CHEMBL375971
CHEMBL:CHEMBL44011
CHEMBL:CHEMBL458602
CHEMBL:CHEMBL480626
CHEMBL:CHEMBL528316
CHEMBL:CHEMBL539954
CHEMBL:CHEMBL541887
CHEMBL:CHEMBL543876
CHEMBL:CHEMBL555242
CHEMBL:CHEMBL561679
CHEMBL:CHEMBL577673
CHEMBL:CHEMBL593110
CHEMBL:CHEMBL593366
CHEMBL:CHEMBL594772
CHEMBL:CHEMBL595682
CHEMBL:CHEMBL595911
CHEMBL:CHEMBL595912
CHEMBL:CHEMBL598270
CHEMBL:CHEMBL609570
CHEMBL:CHEMBL610767
CHEMBL:CHEMBL73380
CHEMBL:CHEMBL76012
CHEMBL:CHEMBL83159
CHEMBL:CHEMBL84472
CHLORALIN
CHLORAMPHENICOL PALMITATE A palmitate ester that has formula C27H42Cl2N2O6.
CHLORBROMURON
CHLORDANE A cyclodiene organochlorine insecticide that has formula C10H6Cl8.
CHLORDIAZEPOXIDE A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.
CHLORFENAPYR
CHLORHEXIDINE GLUCONATE A D-gluconate adduct that has formula C34H54Cl2N10O14.
CHLORHEXIDINE HYDROCHLORIDE
CHLORMADINONE
CHLORMADINONE ACETATE A corticosteroid hormone that has formula C23H29ClO4.
CHLORMIDAZOLE
CHLOROBENZILATE A diarylmethane that has formula C16H14Cl2O3.
CHLOROPHACINONE A diarylmethane that has formula C23H15ClO3.
CHLOROTHALONIL
CHLOROTRIANISENE
CHLOROXINE
CHLOROXURON
CHLORPROMAZINE HYDROCHLORIDE
CHLORQUINALDOL
CICLESONIDE
CICLOPIROX OLAMINE
CILNIDIPINE
CITICOLINE SODIUM
CLASCOTERONE
CLOBETASOL PROPIONATE The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis.
CLOCORTOLONE PIVALATE
CLOFLUCARBAN
CLOMIPRAMINE HYDROCHLORIDE
CLOROPHENE
CLOSTEBOL
CLOXYQUIN
CORTICOSTERONE A 21-hydroxy steroid that is consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
CORTODOXONE
COUMAPHOS An organothiophosphate insecticide that has formula C14H16ClO5PS.
CR 1447
CRIDANIMOD
CROMOLYN SODIUM
CRUFOMATE
CYAZOFAMID A member of the class of imidazoles carrying dimethylsulfamyl, cyano, chloro and 4-tolyl substituents at positions 1, 2, 4 and 5 respectively. A fungicide used mainly for controlling Oomycete and Plasmodiophora diseases on potatoes and tomatoes. It is a skin and eye irritant and is moderately toxic to birds, most aquatic organisms, honeybees and earthworms.
CYCLANDELATE
CYCLOHEXIMIDE A piperidine antibiotic that has formula C15H23NO4.
CYPROTERONE
DANAZOL A 17beta-hydroxy steroid that has formula C22H27NO2.
DARBUFELONE MESYLATE
DAROLUTAMIDE
DAZOMET A dithiocarbamic ester that is 1,3,5-thiadiazinane with a thione moiety at position 2 and in which the hydrogens attached to the nitrogens are replaced by methyl groups. A fungicide, herbicide and nematicide, it is used prior to sowing or planting for the control of soil fungi, nematodes, bacteria and germinating weeds, and as fumigant for poultry litter and eggs to control Salmonella. It is a non-ozone-depleting alternative to methyl bromide.
DEFLAZACORT
DEMECOLCINE
DEQUALINIUM CHLORIDE
DESLANOSIDE
DESOGESTREL
DESOXYCORTICOSTERONE
DESOXYCORTICOSTERONE ACETATE
DESOXYCORTICOSTERONE PIVALATE
DEUTENZALUTAMIDE
DEVAZEPIDE An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used for treatment of gastrointestinal disorders.
DEXAMETHASONE DIPROPIONATE
DEXAMETHASONE VALARATE
DEXBUDESONIDE
DEZANDRODEG
DIBEKACIN
DIBENZOYLMETHANE A beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects.
DIBUTYLDICHLOROSTANNANE
DICHLOFLUANID
DICHLORODIMETHYLSTANNANE
DICHLOROTRIPHENYLBISMUTHANE
DICHLOROXYLENOL
DICHLORVOS An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate.
DICOFOL A tertiary alcohol that is DDT in which the benzylic hydrogen has been replaced by a hydroxy group.
DICYCLOHEXYLCARBODIIMIDE
DIDECYLDIMETHYLAMMONIUM CHLORIDE
DIELDRIN An organochlorine insecticide that has formula C12H8Cl6O.
DIETHYLCARBAMAZINE CITRATE
DIFENOCONAZOLE
DIFLOXACIN HYDROCHLORIDE
DIFLUCORTOLONE 21-VALERATE
DIFLUPREDNATE
DIGITOXIN
DIHYDROTESTOSTERONE
DIMETHENAMID
DIMETHISOQUIN HYDROCHLORIDE
DIMETHOMORPH A mixture of (E)- and (Z)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the Z isomer has fungicidal activity.
DIMETHYLAMINOETHANOL
DIMETHYLCURCUMIN
DINALINE
DINITRAMINE
DINITRO CRESOL
DINOSEB A racemate composed of equimolar amounts of (R)- and (S)-dinoseb.
DINOTERB
DIPHENOXYLATE HYDROCHLORIDE
DIPYRITHIONE
DITHIANON
DITHIAZANINE IODIDE
DITHIODIMORPHOLINE
DITIOCARB SODIUM
DOCUSATE SODIUM
DODECYL GALLATE
DODINE
DOFETILIDE
DROMOSTANOLONE
DROSPIRENONE
DUTASTERIDE Finasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland.
DYDROGESTERONE
ECONAZOLE NITRATE
EFAROXAN
EFONIDIPINE
EMETINE
EMETINE HYDROCHLORIDE
ENCLOMIPHENE CITRATE
ENDOSULFAN A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.
ENDOSULFAN SULFATE
ENILCONAZOLE A racemate comprising equimolar amounts of (R)- and (S)-enilconazole. A fungicide used to control a wide range of fungi including Tilletia and Helminthosporium spp. on fruit, vegetables and ornamentals. It is also used in veterinary medicine as a topical antimycotic.
ENOBOSARM
EPITESTOSTERONE An androstanoid that is the C-17 epimer of testosterone.
EPITIOSTANOL
ERGOCALCIFEROL
ERGONOVINE
ESCULIN
ESTRADIOL 17-ACETATE
ESTRADIOL 3-BENZOATE
ESTRADIOL BENZOATE
ESTRADIOL CYPIONATE
ESTRADIOL DIPROPIONATE A steroid ester that has formula C24H32O4.
ESTRADIOL ENANTHATE
ESTRADIOL PHOSPHATE
ESTRADIOL PROPIONATE
ESTRADIOL VALERATE A steroid ester that has formula C23H32O3.
ESTRAMUSTINE
ESTRAMUSTINE PHOSPHATE
ESTRAMUSTINE PHOSPHATE SODIUM
ESTRIOL
ETHINYLESTRADIOL/DROSPIRENONE/PRASTERONE
ETHISTERONE
ETHOFUMESATE
ETHYLESTRENOL
ETHYNODIOL DIACETATE A terminal acetylenic compound that has formula C24H32O4.
ETOCRYLENE
ETONITAZENE
ETONOGESTREL
EXALAMIDE
EXIFONE
FANDOSENTAN POTASSIUM
FANETIZOLE
FEBANTEL
FENAMIDONE
FENARIMOL A racemate comprising equimolar amounts of (R)- and (S)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union.
FENBUCONAZOLE A racemate comprising equimolar amounts of (R)- and (S)-fenbuconazole. A fungicide used to control a range of diseases including powdery mildew, black rot and scab.
FENCHLORAZOL-ETHYL
FENDILINE HYDROCHLORIDE
FENHEXAMID An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol.
FENOVERINE
FENPYROXYMATE
FEPRAZONE
FERBAM
FIPEXIDE HYDROCHLORIDE
FIPRONIL A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
FLUACIZINE
FLUAZINAM A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens.
FLUCYTOSINE An organofluorine compound that has formula C4H4FN3O.
FLUDIOXONIL A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria.
FLUDROCORTISONE A mineralocorticoid that has formula C21H29FO5.
FLUFENACET
FLUFENOXURON
FLUMETHASONE
FLUNISOLIDE ANHYDROUS
FLUOCINOLONE ACETONIDE A fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatment of various skin disorders.
FLUOCINONIDE
FLUORODIFEN
FLUOROMETHOLONE A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.
FLUOROSALAN
FLUOXASTROBIN
FLUOXYMESTERONE An anabolic androgenic steroid that has formula C20H29FO3.
FLUPREDNISOLONE
FLURANDRENOLIDE
FLUROCHLORIDONE
FLUROGESTONE ACETATE
FLUSILAZOLE A organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops.
FLUSPIRILENE
FLUTOLANIL A member of the class of benzamides, obtained by formal condensation of the carboxy group of 2-(trifluoromethyl)benzoic acid with the amino group of 3-(ispropyloxy)aniline. A fungicide used to control a range of pathogens especially Rhizoctonia spp. on rice, turf and other crops.
FOLPET
FORMESTANE
FRENTIZOLE
FUDOSTEINE
FURAZABOL
FURFURAL
GALETERONE
GEMCITABINE HYDROCHLORIDE
GESTODENE
GESTRINONE
GIPARMEN
GLPG-0492
GLPG0492
GLUTATHIONE DISULFIDE A glutathione derivative that has formula C20H32N6O12S2.
GLYCYRRHIZIC ACID
GRAMICIDIN S
GRISEOFULVIN Antibiotic produced by Penicillium griseofulvum.
GSK2849466
GSK2881078
GUGGULSTERONE
HALAZONE
HALCINONIDE
HALOBETASOL PROPIONATE
HALOPROGIN
HE3235
HEPTANE
HEXACONAZOLE A racemate comprising equimolar amounts of (R)- and (S)-hexaconazole. An agricultural fungicide introduced in the 1980s, it is not approved for use within the European Union.
HEXADECYLTRIMETHYLAMMONIUM CHLORIDE
HEXYLRESORCINOL
HOMATROPINE HYDROBROMIDE
HPTE
HYDRAMETHYLNON A member of the class of hydrazones that is used as an insecticide for control of ants and cockroaches.
HYDROCORTISONE PROBUTATE
HYDROCORTISONE SODIUM PHOSPHATE
HYDROCORTISONE SODIUM SUCCINATE
HYDROCORTISONE VALERATE
HYDROXYFLUTAMIDE An anilide that has formula C11H11F3N2O4.
HYMECROMONE
IDARUBICIN HYDROCHLORIDE
IDEBENONE
INDINAVIR SULFATE
INDOCATE
INDOXACARB
INGLIFORIB
IODOCARB
IOPAMIDOL
IPCONAZOLE
ISOFENPHOS A salicylate that has formula C15H24NO4PS.
ISOFLUPREDONE ACETATE
ISOPROPYL UNOPROSTONE
ISOTRETINOIN A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.
ISRAPAFANT
JNJ-63576253
KEPONE
KRESOXIM-METHYL
LACTATE
LACTOFEN
LANATOSIDE C
LASALOCID A SODIUM
LAUROCAPRAM
LEMILDIPINE
LERCANIDIPINE HYDROCHLORIDE
LESTAURTINIB
LEUPROLIDE ACETATE
LGD-2941
LGD-4033
LIMONIN A hexacyclic triterpenoid that has formula C26H30O8.
LIRANAFTATE
LOFEPRAMINE HYDROCHLORIDE
LOPERAMIDE A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
LORACARBEF
LORATADINE
LULICONAZOLE
LY2452473
MALTOTRIOSE A maltotriose trisaccharide in which the glucose residue at the reducing end is in the aldehydo open-chain form.
MAPROTILINE HYDROCHLORIDE
MECHLORETHAMINE HYDROCHLORIDE
MEDRYSONE
MELENGESTROL ACETATE
MELOXICAM
MENADIONE SODIUM BISULPHITE
MEPANIPYRIM A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying additional methyl and 1-propynyl substituents at positions 4 and 6 respectively. A fungicide used to control a wide range of diseases including grey mould on strawberries, tomatoes and cucumabers, and scab on apples and pears.
MEPHOBARBITAL A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at N-1 by a methyl group and at C-5 by ethyl and phenyl groups.
MEPREDNISONE
MERADIMATE
MERCURIC IODIDE
MESTANOLONE
METCONAZOLE
METFORMIN HYDROCHLORIDE
METHANDROSTENOLONE
METHENOLONE ENANTHATE
METHIDATHION An organothiophosphate insecticide that has formula C6H11N2O4PS3.
METHYL YELLOW
METHYLPREDNISOLONE ACETATE
METHYLPREDNISOLONE SODIUM SUCCINATE
METHYLTESTOSTERONE A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position.
METHYLTHIOURACIL A 9,11,15-octadecatrienoic acid that has formula C5H6N2OS.
METILDIGOXIN
METITEPINE
METRIBOLONE
MEVASTATIN A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group and in which the lactone moiety has been hydrolysed to the corresponding delta-hydroxy-carboxylic acid. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals.
MEZLOCILLIN
MIBEFRADIL DIHYDROCHLORIDE
MIBOLERONE An androgen that is nalandrone carrying two methyl substituents at positions 7alpha and 17.
MIDAZOLAM HYDROCHLORIDE
MILBEMYCIN A4
MINOPAFANT
MIRIPIRIUM CHLORIDE
MIRISTALKONIUM CHLORIDE
MITOBRONITOL
MK-0773
MOCLOBEMIDE
MONATEPIL
MONENSIN SODIUM
MORICIZINE HYDROCHLORIDE
MYCOPHENOLATE
MYCOPHENOLATE MOFETIL
NAFOXIDINE A benzene that has formula C29H31NO2.
NALED A dialkyl phosphate that has formula C4H7Br2Cl2O4P.
NANDROLONE DECANOATE A steroid ester that has formula C28H44O3.
NANDROLONE PHENPROPIONATE A 3-phenylpropionate ester that has formula C27H34O3.
NAPROPAMIDE
NARASIN
NEFAZODONE HYDROCHLORIDE
NELIVAPTAN
NICARDIPINE HYDROCHLORIDE
NIHYDRAZONE
NILUTAMIDE
NILVADIPINE
NIMETAZEPAM A nitrazepam which is substituted at positions 1 by a methyl groups. It is used as an anticonvulsant and as a hypnotic for the short-term management of insomnia.
NISOLDIPINE
NITRALIN
NITROBLUE TETRAZOLIUM CHLORIDE
NITROFEN An organic molecular entity that has formula C12H7Cl2NO3.
NITROFURAZONE
NITROSCANATE
NITROXOLINE
NOCODAZOLE A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.
NONYL 4-HYDROXYBENZOATE
NORELGESTROMIN
NORETHINDRONE
NORETHYNODREL
NORGESTIMATE
NORGESTREL A 17-hydroxy steroid that has formula C21H28O2.
NORTRIPTYLINE HYDROCHLORIDE
O-PHENANTHROLINE
OCTAVERINE
OCTOCRYLENE
OCTYL_GALLATE
ORBIFLOXACIN
ORTHO-PHTHALALDEHYDE
ORYZALIN A sulfonamide that is benzenesulfonamide substituted at positions 3 and 5 by nitro groups and at position 4 by a dipropylamino group.
OSATERONE ACETATE
OUABAIN
OXABOLONE CIPIONATE
OXADIAZON An aromatic ether that has formula C15H18Cl2N2O3.
OXANDROLONE An oxa-steroid that has formula C19H30O3.
OXAPIUM IODIDE
OXAZEPAM A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
OXENDOLONE
OXYCARBOXIN
OXYFLUORFEN
OXYPHENISATIN
OXYPHENISATIN ACETATE
OXYQUINOLINE
OXYQUINOLINE SULFATE
PALMATINE CHLORIDE HYDRATE
PAPAVERINE HYDROCHLORIDE
PARAMETHASONE ACETATE
PARAOXON An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
PARBENDAZOLE
PENCONAZOLE A racemate comprising equal amounts of (R)- and (S)-penconazole. A fungicide used to control powdery mildew, scab and other pathogenic Ascomycetes, Basidiomycetes and Deuteromycetes.
PENCYCURON A member of the class of ureas carrying 4-chlorobenzyl and cyclopentyl substituents at position 1 and a phenyl substituent at position 3. A fungicide used to control diseases caused by Rhizoctonia solani and Pellicularia spp. It is not highly toxic to mammals but is moderately toxic to birds, most aquatic organisms, honeybees and earthworms.
PENFLURIDOL
PENTACHLORONITROBENZENE
PENTAMIDINE ISETHIONATE
PERBROMOBENZENE
PERHEXILINE MALEATE
PF-03882845
PF0998425
PHANQUONE
PHENELZINE SULFATE
PHENFORMIN HYDROCHLORIDE
PHENOXYCARB
PHENYL SALICYLATE A benzoate ester that is the phenyl ester of salicylic acid.
PHENYLARSINE OXIDE An arsine oxide derived from phenylarsine.
PHENYLETHYL ALCOHOL
PHOSALONE A member of the class of 1,3-benzoxazoles carrying a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2 and a chloro group at position 6. It is an organothiophosphate insecticide.
PILSICAINIDE
PIMETHIXENE MALEATE
PIMOZIDE
PIPERILATE ETHOBROMIDE
PIPERONAL
PIRETANIDE
PITAVASTATIN CALCIUM
PK 11195
PODOFILOX
PRAZEPAM
PREDNISOLONE ACETATE
PREDNISOLONE HEMISUCCINATE
PRIMIDONE A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
PROADIFEN HYDROCHLORIDE
PROCHLORAZ A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables.
PROCYMIDONE An azabicycloalkane that is 1,5-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione in which the amino hydrogen is replaced by a 3,5-dichlorophenyl group. A fungicide widely used in horticulture as a seed dressing, pre-harvest spray or post-harvest dip for the control of various diseases.
PROMAZINE HYDROCHLORIDE
PROMETHAZINE HYDROCHLORIDE
PROPANIL An anilide that has formula C9H9Cl2NO.
PROPARGITE
PROPICONAZOLE The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds.
PROROXAN
PRULIFLOXACIN
PRUXELUTAMIDE
PUROMYCIN HYDROCHLORIDE
PYRACLOSTROBIN
PYRAZOPHOS
PYRIDABEN A pyridazinone that has formula C19H25ClN2OS.
PYRIPROXYFEN
PYRITHIONE SODIUM
PYRROLNITRIN
PYRVINIUM PAMOATE
QUIFENADINE
QUININE ETHYLCARBONATE
QUININE SULFATE
RABEPRAZOLE SODIUM
RAD-140
REZVILUTAMIDE
RHODAMINE
RIFAMYCIN SODIUM
RO 40-6055
RO3280
ROCURONIUM BROMIDE
ROTENONE A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica).
RUBITECAN
SALINAZID
SCLAREOL
SECURININE
SERTRALINE HYDROCHLORIDE
SEVITERONEL
SODIUM DIMETHYLCARBAMODITHIOATE
SORAFENIB TOSYLATE
SORBIC ACID A hexadienoic acid with double bonds at C-2 and C-4; it has four geometrical isomers, of which the trans,trans-form is naturally occurring.
SPARFLOXACIN
SPIRADOLINE
SPIRAMIDE An azaspiro compound that consists of 1,3,8-triazaspiro[4.5]decan-4-one having a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl attached to N-8. Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spiperone but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behaviour.
STANOLONE
STANOZOLOL
STIROFOS
SULFACARBAMIDE
SULFAQUINOXALINE
SULFISOXAZOLE A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms.
SYROSINGOPINE
TANESPIMYCIN A 19-membered macrocyle comprising geldanamycin with its 17-methoxy substituent replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumor effects.
TAZOBACTAM SODIUM
TEBUCONAZOLE A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops.
TEBUFENOZIDE A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.
TEBUFENPYRAD
TECTOQUINONE
TELITHROMYCIN
TEMEFOS
TEROXIRONE
TESTOLACTONE
TESTOSTERONE BUCYCLATE
TESTOSTERONE CYPIONATE
TESTOSTERONE ENANTHATE An enanthate ester that has formula C26H40O3.
TESTOSTERONE PROPIONATE A steroid ester that has formula C22H32O3.
TETRABUTYLAMMONIUM BROMIDE
TETRACONAZOLE A racemate comprising equal amounts of (R)- and (S)-tetraconazole. A fungicide used to control a range of fungal infections including powdery mildew, rusts, bunt, loose smut and scab.
TETRADIFON
TETRAMETHRIN A phthalimide insecticide that has formula C19H25NO4.
THIDIAZURON
THIOACETAZONE
THIOPHENE
THIOSEMICARBAZIDE
TIBOLONE
TILIQUINOL
TILNOPROFEN ARBAMEL
TIOCONAZOLE
TO-901317
TOFISOPAM
TOLONIUM CHLORIDE
TOLUIC ACID
TOLVAPTAN
TOLYLFLUANID
TOMATINE
TOREMIFENE CITRATE
TRELANSERIN
TRENBOLONE ACETATE
TREQUINSIN HYDROCHLORIDE
TRIAMCINOLONE DIACETATE
TRIAMTERENE
TRIBROMSALAN
TRIBUTYLCHLOROSTANNANE
TRIBUTYLTIN-OXIDE
TRICHLOROMONOFLUOROMETHANE
TRICLOCARBAN A member of the class of ureas that is urea substituted by a 4-chlorophenyl and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.
TRICLOSAN An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
TRIFLUMIZOLE
TRIFORINE A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust.
TRILOSTANE
TRIMETHYL-OCTADECYL-AMMONIUM CHLORIDE
TRIPARANOL
TRIPHENYL PHOSPHATE An aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol.
TRIPHENYLBISMUTHINE
TRIPHENYLSTANNANOL
TRIPHENYLSTANNYL ACETATE
TRIS(2,3-DIBROMOPROPYL)PHOSPHATE
TRITON X
TROPOLONE A cyclic ketone that has formula C7H6O2.
VALNEMULIN
VALRUBICIN
VATALANIB
VINBLASTINE SULFATE
VINBURNINE
VINCLOZOLIN A racemate comprising equimolar amounts of (R)- and (S)-vinclozolin. A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control Botrytis, Sclerotinia and Monilia spp.
VINDESINE SULFATE
VINORELBINE TARTRATE
VK5211
WARFARIN POTASSIUM
WHILE OLIVETOL
ZAFIRLUKAST A carbamate ester that has formula C31H33N3O6S.
ZANOTERONE
ZERANOL
ZOLPIDEM TARTRATE
ZOMEPIRAC SODIUM
ZOXAMIDE
BELVARAFENIB
COBIMETINIB
ENCORAFENIB
EXARAFENIB
LIFIRAFENIB
LY-3009120
LY3009120
TOVORAFENIB
XL281
CETUXIMAB
PANITUMUMAB
NAV2729
2(S)-AMINO-6-BORONOHEXANOIC ACID
A1P
CHEMBL:CHEMBL1099167
CHEMBL:CHEMBL1099168
COMPOUND 9 [PMID: 23472952]
GLYCEROL PHENYLBUTYRATE
GSK126
NIRAPARIB
OLAPARIB A member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine.
PAMIPARIB
FUROSPONGOLIDE
PROTEASOME INHIBITOR
ALBIGLUTIDE
DULAGLUTIDE
TRAMADOL
3,5-DINITROCATECHOL (OR-486)
BENZOXATHIAN
CEBSULFASE ALFA
CHEMBL:CHEMBL466465
CHEMBL:CHEMBL64239
DECAMETHONIUM A quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents.
DNQX
INDIRUBIN-3'-MONOXIME
MELEVODOPA
PIRENPERONE
TRANILAST
GALSULFASE
PARP/TANKYRASE INHIBITOR 2X-121
RUCAPARIB
TALAZOPARIB
VELIPARIB
VUPANORSEN SODIUM
6-IODOAMILORIDE
AMILORIDE A monocarboxylic acid amide that is N-carbamimidoylpyrazine-2-carboxamide substituted by amino groups at positions 3 and 5 and a chloro group at position 6.
ASC06-IGG1
BENZAMIL A pyrazine that has formula C13H14ClN7O.
COMPOUND 3B [PMID: 34097384]
COMPOUND 5B [PMID: 25974655]
DIMINAZENE A triazene derivative that is triazene in which each of the terminal nitrogens is substituted by a 4-carbamimidoylphenyl group.
H+
JNJ-67869386
JNJ-799760
MAMBALGIN-1
NS383
PB2+
PI-HEXATOXIN-HI1A
PI-THERAPHOTOXIN-HM3A
PSALMOTOXIN 1
[125I]PSALMOTOXIN 1
A-317567
CD2+
AGMATINE A primary amino compound that has formula C5H14N4.
APETX2
ARCAINE
GD3+
GMQ
LYSOPHOSPHATIDYLCHOLINE A compound resulting from partial hydrolysis of a phosphatidylcholine which removes one of the fatty acid groups.
SALICYLIC ACID A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves.
UGR 9-1
ASPARAGINASE
COMPOUND 5 [STECULA ET AL., 2020]
CALASPARGASE PEGOL
ERYASPASE
4-PHENYLBUTYRIC ACID A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
PEGARGIMINASE
ISONIAZID
AZ13824374
BAY-850
COMPOUND 23 [PMID: 31398032]
COMPOUND 33 [PMID: 26230603]
COMPOUND 57 [PMID: 26155854]
COMPOUND 60 [PMID: 26155854]
GSK8814
(R,S)-INDATRALINE
2-METHOXY-1,4-NAPHTHOQUINONE A naphthoquinone that is naphthalene-1,4-dione substituted by a methoxy group at position 2. It has been isolated from the roots of Rubia yunnanensis.
3,3'-DIFLUOROBENZALDAZINE
3,5-DIPHENYLISOXAZOLE
4'-METHOXY-AURONE
4'-METHOXYFLAVONE
5-FLUOROURIDINE An organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.
6-BROMOFLAVONE
6-HYDROXYFLAVONE A hydroxyflavonoid that has formula C15H10O3.
AG 1295
AG1478
ALBENDAZOLE
AMSACRINE
ANGUIDIN
ANISOMYCIN
AURIN A diarylmethane that has formula C19H14O3.
BETA-TOXICAROL
BIX-01294
CALCIMYCIN An aminobenzoic acid that has formula C29H37N3O6.
CALYCOSIN
CANTHARIDIC_ACID
CHEMBL:CHEMBL101815
CHEMBL:CHEMBL1078244
CHEMBL:CHEMBL1093369
CHEMBL:CHEMBL1170485
CHEMBL:CHEMBL1224483
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CHEMBL:CHEMBL1998001
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CHRYSIN DIMETHYL ETHER
CINOBUFAGIN A steroid lactone that has formula C26H34O6.
CP55940
CUCURBITACIN B A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23; a hydroxy function at C-25 is acetylated.
CYCLOASPEPTIDE A
DAIDZEIN A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'.
DAIDZIN
DAPH
DILAZEP
DIPHENYLENEIODONIUM
DRB
ENOXIMONE
ENTINOSTAT
FASUDIL HYDROCHLORIDE
FIDUXOSIN
FLUNARIZINE
GELDANAMYCIN A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. it is an ansamycin antibiotic and thus shows antimicrobial activity against many gram-positive and some gram-negative bacteria.
GR 127935 A member of the class of benzamides obtained by formal condensation of the carboxy group of 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid and the anilino group of 4-methoxy-3-(4-methylpiperazin-1-yl)aniline. Potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). Displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Centrally active following oral administration.
HARMALINE A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
HARMAN An indole alkaloid fundamental parent with a structure of 9H-beta-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A.
HARMINE HYDROCHLORIDE
HISPIDULIN A monomethoxyflavone that is scutellarein methylated at position 6.
IMD-0354
IPRIFLAVONE
ISOLIQUIRITIGENIN A member of the class of chalcones that is trans-chalcone hydroxylated at C-2', -4 and -4'.
ISOVELLERAL An aldehyde that has formula C15H20O2.
JNJ1661010
KAMEBANIN
KN62
LEFLUNOMIDE A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
METHOXYVONE
N6-PHENYLADENOSINE
NILE RED
NITROBENZYLMERCAPTOPURINE RIBONUCLEOSIDE
ONONIN
OXOPURPUREINE
PD98059
PECTOLINARIGENIN
PIFEXOLE
QUINACRINE
RUTAECARPINE
SHINJULACTONE B
SIB-1757
SIB-1893
STREPTONIGRIN Complex cytotoxic antibiotic obtained from Streptomyces flocculus or S. rufochronmogenus. It is used in advanced carcinoma and causes leukopenia.
SYK INHIBITOR III
TBBT
THIOINOSINE
THUNBERGINOL E
TREQUINSIN
TRIMETHOBENZAMIDE HYDROCHLORIDE
VINCAMINE
WIN 62,577
2-METHOXYESTRADIOL
CHEMBL:CHEMBL1200567
CHEMBL:CHEMBL528181
CHEMBL:CHEMBL605084
TILDRAKIZUMAB
A011
ALNODESERTIB
ATM INHIBITOR M 3541
AVELUMAB
AZD0156
AZD1390
AZD6482
AZD7648
BAY-8400
BENDAMUSTINE
BERZOSERTIB
CAMONSERTIB
CERALASERTIB
CHEMBL:CHEMBL1519374
CHEMBL:CHEMBL375673
CHEMBL:CHEMBL578061
CHEMBL:CHEMBL606460
CHEMBL:CHEMBL74852
CP466722
E-7820
ELIMUSERTIB
ENPIROLINE
FLUNARIZINE DIHYDROCHLORIDE
HEPTACHLOR A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8.
INDISULAM
KU-0060648
KU-55933
KU-60019
LARTESERTIB
MITOTANE
NAFTIFINE HYDROCHLORIDE
NU-7441
PEGYLATED SN-38 CONJUGATE PLX038
PERMETHRIN A cyclopropanecarboxylate ester in which the esterifying alcohol is 3-phenoxybenzyl alcohol and the cyclopropane ring is substituted with a 2,2-dichlorovinyl group and with gem-dimethyl groups.
PJ34
SCHISANHENOL
TUVUSERTIB
XRD-0394
ACETYLDIGITOXIN
ALMITRINE
ALUMINUM
ARTEMETHER
BEPRIDIL
CHLOROPROCAINE Procaine in which one of the hydrogens ortho- to the carboxylic acid group is substituted by chlorine. It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. It has the advantage over lidocaine of constricting blood vessels, so reducing bleeding.
EPLERENONE A steroid acid ester that has formula C24H30O6.
ISTAROXIME
ARTENIMOL
ARTESUNATE
MIPSAGARGIN
OZ277
PIPERAQUINE
PYRONARIDINE
TGN4
THAPSIGARGIN An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations.
VANADATE
EMPAGLIFLOZIN A C-glycosyl compound consisting of a beta-glucosyl residue having a (4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl group at the anomeric centre. A sodium-glucose co-transporter 2 inhibitor used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
DESFLURANE
ENFLURANE An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups.
ISOFLURANE An organofluorine compound that has formula C3H2ClF5O.
SEVOFLURANE An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
ABEPRAZAN
ESOMEPRAZOLE MAGNESIUM
ESOMEPRAZOLE STRONTIUM
ILAPRAZOLE
LINAPRAZAN
OMEPRAZOLE MAGNESIUM
PANTOPRAZOLE SODIUM
TEGOPRAZAN
VONOPRAZAN FUMARATE
HALOTHANE A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position.
METHOXYFLURANE
BEDAQUILINE FUMARATE
ENOXACIN
AZ20
GARTISERTIB
M4344
VE-821
(-)-N-PORPHYNORAPOMORPHINE
(S)-ROSCOVITINE
4-HYDROXYTAMOXIFEN
ALOXISTATIN
ANGUSTIBALIN
AROMOLINE
BW723C86
CEPHARANTHINE An isoquinoline that has formula C37H38N2O6.
CHEMBL:CHEMBL1169388
CHEMBL:CHEMBL1256660
CHEMBL:CHEMBL1287980
CHEMBL:CHEMBL1287983
CHEMBL:CHEMBL1306556
CHEMBL:CHEMBL1334191
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CHEMBL:CHEMBL582473
CHEMBL:CHEMBL582699
CHEMBL:CHEMBL585502
CHEMBL:CHEMBL586024
CHEMBL:CHEMBL586937
CHEMBL:CHEMBL588038
CHEMBL:CHEMBL589245
CHEMBL:CHEMBL589694
CHEMBL:CHEMBL589715
CHEMBL:CHEMBL590168
CHEMBL:CHEMBL590686
CHEMBL:CHEMBL591126
CHEMBL:CHEMBL591404
CHEMBL:CHEMBL592316
CHEMBL:CHEMBL596633
CHEMBL:CHEMBL599098
CHEMBL:CHEMBL600353
CHEMBL:CHEMBL600747
CHEMBL:CHEMBL602946
CHEMBL:CHEMBL603952
CHEMBL:CHEMBL607253
CHEMBL:CHEMBL607309
CLEMASTINE FUMARATE
CLOFOCTOL
CLOROTEPINE
CUDRAFLAVONE B An extended flavonoid that consists of a pyranochromane skeleton that is 2H,6H-pyrano[3,2-g]chromen-6-one substituted by geminal methyl groups at position 2, a 2,4-dihydroxyphenyl group at position 8, a hydroxy group at position 5 and a prenyl group at position 7. Isolated from Morus alba and Morus species it exhibits anti-inflammatory activity.
CYCLOVALONE
ENCLOMIPHENE
ENNIATIN B
FANGCHINOLINE
FLAVOKAWAIN B
FLUPENTHIXOL
GEDUNIN A pentacyclic triterpenoid natural product found particularly in Azadirachta indica and Cedrela odorata.
GEOPYXIN A
GERONTOXANTHONE H
LOBARIC ACID
MAPROTILINE
MEFLOQUINE HYDROCHLORIDE
METHIOTHEPIN MESYLATE
METHIXENE HYDROCHLORIDE
N-AMINOHEXYL-5-CHLORO-1-NAPTHALENESULFONAMIDE HYDROCHLORIDE
NANAOMYCIN
PD173074 A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N(3) is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor.
PERPHENAZINE A member of the class of phenothiazines that is phenothiazine having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
PROCHLORPERAZINE A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
PROPYLPYRAZOLETRIOL
PYRITHIONE
QUINESTROL
SAQUINAVIR
SB 242084
SCLEROTIORIN
SERTACONAZOLE NITRATE
SPHAEROPSIDIN A
SU9516
TAMOXIFEN A stilbenoid that has formula C26H29NO.
TANSHINONE I
TEGASEROD MALEATE
TETRANDRINE
THIORIDAZINE HYDROCHLORIDE
THIOTHIXENE
TUBERCIDIN
VER-3323
XANTHOANGELOL
XANTHOANGELOL F
ALISERTIB SODIUM
AMG-900
AURORA A KINASE INHIBITOR MK5108
AURORA KINASE INHIBITOR AMG 900
AURORA KINASE INHIBITOR II
BARASERTIB
BARASERTIB-HQPA
BETA-CARBOLINE
BI-847325
CDK2 INHIBITOR IV
COMPOUND 10 [PMID: 19402633]
COMPOUND 16 [PMID: 18945615]
COMPOUND 25 [PMID: 20855207]
COMPOUND 38 [PMID: 20817473]
COMPOUND 46 [PMID: 16451062]
CYC116
DANUSERTIB
DIMETHYLADENINE
DUBERMATINIB
ENMD-981693
EP-0042
EUPATORIN
G&OUML; 6976
GSK1070916
GSK143
GSK2334470
GSK2646264
MK-5108
MK-6592
MLN8054
N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE An aminopyrimidine that has formula C21H18F3N5O.
NERVIANO
PF-03814735
PLATINUM COMPOUND
RHO KINASE INHIBITOR IV
SK5527
SNS-314
TINENGOTINIB
TOZASERTIB LACTATE
TTP-607
VIC 1911
VTX-11E
XMD-12
ZM447439
AR-AO-14418
AURORA B/C KINASE INHIBITOR GSK1070916A
BAY 61-3606
BELUMOSUDIL
BI-811283
BMS-345541
BX-795
CHEMBL:CHEMBL535331
COMPOUND 1 [PMID: 21742770]
COPANLISIB
IBCASERTIB
NIK INHIBITOR 12F
TAK-632
TAK-901
COMPOUND A [PMID: 41604465]
3-N3-PHPA-LVA
ARGIPRESSIN TANNATE
ARGIPRESTOCIN
ATOSIBAN
BALOVAPTAN
CARBETOCIN Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue of oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.
CONIVAPTAN
CONIVAPTAN HYDROCHLORIDE
D(CH2)5[D-ILE2,ILE4,ALA-NH29]AVP
D(CH2)5[D-ILE2,ILE4,ALA-NH2]AVP
D(CH2)5[D-TYR(ET)2,VAL4,TYR-NH29]AVP
D(CH2)5[TYR(ET)2,VAL4,DES-GLY9]AVP
D(CH2)5[TYR(ME)2,ARG8]VP
D(CH2)5[TYR(ME)2,THR4,PHE(3125I,4N3)-NH29]OVT
D(CH2)5[TYR(ME)2,THR4,PHE(3I,4N3)-NH29]OVT
D(CH2)5[TYR(ME)2,THR4,TYR(3125I)-NH29]OVT
D(CH2)5[TYR(ME)2,THR4,TYR-NH29]OVT
D(CH2)5[TYR(ME)2,THR4]OVT
D(CH2)5[TYR(ME)2]AVP
DESMOPRESSIN A synthetic analogue of vasopressin in which 3-mercaptopropionic acid replaces the cysteine residue at position 1 and D-arginine replaces the residue at position 8. An antidiuretic, it increases urine concentration and decreases urine production, and is used (usually as the trihydrate of the acetic acid salt) to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions. It is also used in the diagnosis and treatment of cranial diabetes insipidus and in tests of renal function.
DVDAVP
D[CHA4]AVP
D[D-PAL2]AVP
D[D-PHE2]AVP
D[LEU4]AVP
D[PEN1,TYR(ME)2]AVP
F180
FELYPRESSIN
L023103
LIT-001
LS-192629
LVP
MOZAVAPTAN
OH-LVA
OPC-21268
OPC-51803
PECAVAPTAN
PMX53
RO5028442
RWJ-351647
SATAVAPTAN
SELEPRESSIN
SRX-246
SRX246
SRX251
SSR126768A
TERLIPRESSIN
VASOPRESSIN TANNATE
YM 218
YM 471
[125I]3-N3-PHPA-LVA
[125I]OH-LVA
[3H]AVP (HUMAN, MOUSE, RAT)
[3H]D(CH2)5[TYR(ME)2]AVP
[D-ARG8]INOTOCIN
[PHAA1,D-TYR(ET)2,LYS6,DES-GLY9]AVP
[PHAA1,D-TYR(ET)2,VAL4,LYS6,TYR-NH28,DES-GLY9]AVP
[PHAA1,D-TYR(ME)2,ARG6,TYR-NH29]AVP
[PHAA1,D-TYR2,VAL4,ARG6,ARG-NH29]AVP
[TBAA1,D-TYR(ET)2,VAL4,LYS6,ARG-NH28,DES-GLY9]AVP
[THR4,GLY7]OT
[VAL4]AVP
[3H]D[CHA4]AVP
[3H]NELIVAPTAN
D(CH2)5[D-ILE2,ILE4,TYR-NH29]AVP
D(CH2)5[D-ILE2,ILE4]AVP
D(CH2)5[D-ILE2,VAL4,TYR-NH29]AVP
DAVP
D[VAL4,DARG8]VP
FEDOVAPAGON
LIXIVAPTAN
M0002
SKF-105494
TETRA-IODOPHENOLPHTHALEIN
VNA932
[125I]D(CH2)5[D-TYR(ET)2,ILE4,TYR-NH29]AVP
[125I]D(CH2)5[D-TYR(ET)2,VAL4,TYR-NH29]AVP
[3H]DDAVP
[3H]DESGLY-NH2[D-ILE2,ILE4]VP
[3H]SR 121463A
[PHE3]OT
CHEMBL:CHEMBL91638
CW85319
A-910
ADRIXETINIB
BATIRAXCEPT
BEMCENTINIB
BI-505
BMS-777607
BPI-9016
CANLITINIB
COMPOUND 1 [CRUZ-L&OACUTE;PEZ ET AL., 2019]
COMPOUND 19A [PMID: 30503936]
COMPOUND 6LI [CHAN ET AL., 2022]
COMPOUND 8I [PMID: 22765894]
ENAPOTAMAB VEDOTIN
GILTERITINIB FUMARATE
GLESATINIB
GONIOTHALAMIN
GROWTH ARREST SPECIFIC PROTEIN 6
GW843682X
LDC1267
LIGRITINIB
MECBOTAMAB VEDOTIN
MERESTINIB
NINGETINIB
PROTEIN S
RIPK1 INHIBITOR 22B
SITRAVATINIB
SLC-391
TAMNORZATINIB
UNC4203
UNC8969
XL999
ZANZALINTINIB
AMIKACIN An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.
ANTI-PD-L1 MONOCLONAL ANTIBODY
THYROGLOBULIN
&BETA;-SECRETASE INHIBITOR IV
AM-6494
AMG-8718
ATABECESTAT
AZ-4217
AZ3971
AZD-3839
AZD3839
BERGAMOTTIN
BYAKANGELICIN
CHEMBL:CHEMBL2047666
CHEMBL:CHEMBL496451
COMPOUND 11D [PMID: 23981898]
COMPOUND 13 [PMID: 23412139]
COMPOUND 15 [PMID: 25699151]
COMPOUND 16 [PMID: 23412139]
COMPOUND 2 [PMID: 22911925]
COMPOUND 3L [PMID: 30637955]
COMPOUND 6 [PMID: 34553947]
COMPOUND 9 [PMID: 26937601]
COMPOUND J [PMID: 21907142]
CONVOLIDINE
CTS-21166
ELENBECESTAT
EXAMPLE 2 [WO2013004676]
JNJ-67569762
KURARINONE
KUSHENOL A
LANABECESTAT
LY-2811376
LY2811376
LY2886721
LY3202626
NB-360
OXAZINE 89
PF-06684511
PF-06751979
RO5508887
SOPHORAFLAVANONE G
TAK-070
UMIBECESTAT
VERUBECESTAT
COMPOUND 3 [PMID: 27347366]
EXAMPLE 20 [WO2010128058]
EXAMPLE 41 [WO2012028563]
EXAMPLE 92 [WO2012095521]
EXAMPLE 98 [WO2011020806]
HYDROXYETHYLAMINE TRANSITION-STATE INHIBITOR 1
ANTI-CD19 CAR T CELLS AT101
RUBOXISTAURIN
KERACYANIN CATION
APITOLISIB
BINETRAKIN
CIPROFLOXACIN A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
FOSBRETABULIN DISODIUM
HYPERBARIC OXYGEN
INTERFERON ALFA-2B
NALTREXONE HYDROCHLORIDE
NEUROPROTECTIVE AGENT
O-CHLOROACETYLCARBAMOYLFUMAGILLOL
PREGNANT MARE SERUM GONADOTROPIN
PROCARBAZINE HYDROCHLORIDE
RECOMBINANT C5A
RECOMBINANT FLT3 LIGAND
RECOMBINANT INHIBIN
RECOMBINANT INTERLEUKIN-1
SULFORAPHANE
TOPOISOMERASE-II-BETA INHIBITOR RACEMIC XK469
BAZ2-ICR
GSK2801
2-MERCAPTONICOTINIC ACID
2-PICOLINIC ACID
AG 490
BENZTHIAZIDE
CEFOTIAM HYDROCHLORIDE
CEPHALOTHIN SODIUM
CHEMBL:CHEMBL114544
CHEMBL:CHEMBL1201074
CHEMBL:CHEMBL1256738
CHEMBL:CHEMBL1270169
CHEMBL:CHEMBL1304363
CHEMBL:CHEMBL1306524
CHEMBL:CHEMBL1307453
CHEMBL:CHEMBL1346468
CHEMBL:CHEMBL1383812
CHEMBL:CHEMBL1406948
CHEMBL:CHEMBL1412002
CHEMBL:CHEMBL1412489
CHEMBL:CHEMBL1466186
CHEMBL:CHEMBL1503729
CHEMBL:CHEMBL1507526
CHEMBL:CHEMBL1543865
CHEMBL:CHEMBL1565444
CHEMBL:CHEMBL1588237
CHEMBL:CHEMBL1609016
CHEMBL:CHEMBL1814509
CHEMBL:CHEMBL1939687
CHEMBL:CHEMBL1984884
CHEMBL:CHEMBL1989750
CHEMBL:CHEMBL1990783
CHEMBL:CHEMBL199592
CHEMBL:CHEMBL2002487
CHEMBL:CHEMBL2002849
CHEMBL:CHEMBL2094567
CHEMBL:CHEMBL235891
CHEMBL:CHEMBL255068
CHEMBL:CHEMBL258756
CHEMBL:CHEMBL258767
CHEMBL:CHEMBL275177
CHEMBL:CHEMBL312032
CHEMBL:CHEMBL316589
CHEMBL:CHEMBL317115
CHEMBL:CHEMBL338115
CHEMBL:CHEMBL339587
CHEMBL:CHEMBL398363
CHEMBL:CHEMBL401362
CHEMBL:CHEMBL402456
CHEMBL:CHEMBL43078
CHEMBL:CHEMBL487356
CHEMBL:CHEMBL522983
CHEMBL:CHEMBL527584
CHEMBL:CHEMBL527586
CHEMBL:CHEMBL528463
CHEMBL:CHEMBL531296
CHEMBL:CHEMBL533577
CHEMBL:CHEMBL534288
CHEMBL:CHEMBL534353
CHEMBL:CHEMBL538104
CHEMBL:CHEMBL546170
CHEMBL:CHEMBL546975
CHEMBL:CHEMBL547285
CHEMBL:CHEMBL547483
CHEMBL:CHEMBL548615
CHEMBL:CHEMBL56542
CHEMBL:CHEMBL577851
CHEMBL:CHEMBL578109
CHEMBL:CHEMBL578675
CHEMBL:CHEMBL578878
CHEMBL:CHEMBL579550
CHEMBL:CHEMBL579837
CHEMBL:CHEMBL580155
CHEMBL:CHEMBL582478
CHEMBL:CHEMBL582496
CHEMBL:CHEMBL584248
CHEMBL:CHEMBL584458
CHEMBL:CHEMBL585622
CHEMBL:CHEMBL585827
CHEMBL:CHEMBL585999
CHEMBL:CHEMBL586000
CHEMBL:CHEMBL587092
CHEMBL:CHEMBL587994
CHEMBL:CHEMBL588804
CHEMBL:CHEMBL589912
CHEMBL:CHEMBL590186
CHEMBL:CHEMBL591361
CHEMBL:CHEMBL591370
CHEMBL:CHEMBL591618
CHEMBL:CHEMBL592123
CHEMBL:CHEMBL592588
CHEMBL:CHEMBL592611
CHEMBL:CHEMBL599304
CHEMBL:CHEMBL600309
CHEMBL:CHEMBL600738
CHEMBL:CHEMBL600778
CHEMBL:CHEMBL600862
CHEMBL:CHEMBL601385
CHEMBL:CHEMBL602135
CHEMBL:CHEMBL602150
CHEMBL:CHEMBL602206
CHEMBL:CHEMBL602363
CHEMBL:CHEMBL602927
CHEMBL:CHEMBL602954
CHEMBL:CHEMBL602969
CHEMBL:CHEMBL605959
CHEMBL:CHEMBL606167
CHEMBL:CHEMBL84010
CHLORAMBUCIL
CHLORTETRACYCLINE HYDROCHLORIDE
CLOSANTEL A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections.
COMPOUND 1 [PMID: 25719566]
COMPOUND 6A [PMID: 18942826]
COMPOUND 7 [PMID: 25719566]
DAZOXIBEN HYDROCHLORIDE
DEFERIPRONE
DEMECLOCYCLINE HYDROCHLORIDE
DIHYDROERGOCRISTINE MESYLATE
DIPYRIDYL
FLUMEQUINE
FUSARIC ACID An aromatic carboxylic acid that has formula C10H13NO2.
GARCINONE E
GW7647
HARMAN-3-CARBOXYLIC ACID
ISOCONAZOLE
LEVOKETOCONAZOLE
LOMOFUNGIN
MECLIZINE DIHCL
MEDRONIC ACID
METERGOLINE
MIANSERIN HYDROCHLORIDE
NAFRONYL OXALATE
NAFTOPIDIL DIHYDROCHLORIDE
NALIDIXATE SODIUM
NALIDIXIC ACID A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively.
OXOGLAUCINE
PEFLOXACIN MESYLATE
PENTABROMOPHENOL
PHTHALYLSULFATHIAZOLE
PIROXICAM-BETA-CYCLODEXTRIN
PROCHLORPERAZINE EDISYLATE
PROTOCATECHUALDEHYDE
PYRAZINOIC ACID
QUINOLINIC ACID A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
REMACEMIDE HYDROCHLORIDE
S-NITROSOGLUTATHIONE A glutathione derivative that has formula C10H16N4O7S.
SALICYLALDEHYDE THIOSEMICARBAZONE
SR2640
TENOXICAM
TRIAZOLAM A triazolobenzodiazepine that has formula C17H12Cl2N4.
TRIFLUPROMAZINE HYDROCHLORIDE
TRYPTOPHAN
TYRPHOSTIN 51
BENZENE SELENOIC ACID
ANTIESTROGEN
BAY-069
COMPOUND 27 [PMID: 26938474]
COMPOUND 42 [PMID: 26938474]
ANESTHETIC AGENT
BUPIVACAINE HYDROCHLORIDE
HEXAFLUORENIUM
IMMUNOTOXIN
MEMANTINE HYDROCHLORIDE
MEPTAZINOL
MIVACURIUM
SUCCINYLCHOLINE A quaternary ammonium ion that is the bis-choline ester of succinic acid.
EXAGAMGLOGENE AUTOTEMCEL
ABT-737
AI-850
AMINOLEVULINIC ACID
ANG1005
APG-1252-M1
APG-2575
APRINOCARSEN
AZD4320
BCL-2 INHIBITOR BCL201
BEAUVERICIN A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues.
BECLANORSEN
CILENGITIDE
DITIOCARB
DOLASTATIN 10
ENDOTHELIN RECEPTOR ANTAGONIST
EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR
HYDROQUINONE A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
HYPOXANTHINE A purine nucleobase that consists of purine bearing an oxo substituent at position 6.
LISAFTOCLAX
LYSOZYME
MICELLAR PACLITAXEL
MILATAXEL
MULTIDRUG RESISTANCE MODULATOR
OBATOCLAX
OBATOCLAX MESYLATE
OBLIMERSEN
ORAL CONTRACEPTIVE
ORTATAXEL
PELCITOCLAX
POLATUZUMAB VEDOTIN
PROTUBOXEPIN A
RECOMBINANT FAS LIGAND
RECOMBINANT INTERFERON
SAPONIN A glycoside that is a compound containing one or more hydrophilic glycoside moieties combined with a lipophilic triterpenoid or steroid derivative. Found in particular abundance in plant species.
SONROTOCLAX
TAZAROTENE
TESETAXEL
A-1331852
APOGOSSYPOL
FOSELUTOCLAX
SANGIVAMYCIN
BCL3 INHIBITOR JS6
BCL6 PROTAC 15
BCL6 PROTAC A19
BI-3802
BMS-986458
COMPOUND 8C [PMID: 28760529]
FX1
JNJ-65234637
HERBIMYCIN A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It is an ansamycin antibiotic that induces apoptosis and displays antitumour effects.
AC-LYS-[MEALA6,LEU8,DES-ARG9]BRADYKININ
B-10356
B-9430
B-9858
B-9958
BI113823
BRADYKININ A linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation.
CHEMBL:CHEMBL5315550
CHROMAN 28
COMPOUND 11 [PMID: 12812482]
COMPOUND 12 [PMID: 12723943]
D-LYS0-[DES-ARG10]KALLIDIN
ICATIBANT
JMV1431
KALLIDIN A peptide that has formula C56H85N17O12.
LYS-KALLIDIN
MET-LYS-BRADYKININ
MK0686
NG29
NPC 17731
NPC 18565
NVP-SAA164
PS020990
R-715
R-954
SAFOTIBANT
SSR240612
T-KININ
[125I]HPP-DESARG10HOE140
[3H]LYS-[DES-ARG9]BK
[3H]LYS-[LEU8][DES-ARG9]BK
[D-LYS1,DES-ARG10]KALLIDIN
[DES-ARG10]ICATIBANT
[DES-ARG10]KALLIDIN
[DES-ARG11]T-KININ
[DES-ARG9]BRADYKININ
[DES-PHE9,DES-ARG10]KALLIDIN
[DES-PRO8,DES-PHE9,DES-ARG10]KALLIDIN
[LEU8,DES-ARG9]BRADYKININ
[LEU9,DES-ARG10]KALLIDIN
[SAR,D-PHE8,DES-ARG9]BRADYKININ
ANATIBANT
BRADYZIDE
COMPOUND 3 [PMID: 32636746]
DELTIBANT
DEUCRICTIBANT
FASITIBANT CHLORIDE
FR167344
FR173657
FR190997
FR191413
ICATIBANT ACETATE
JMV1116
LABRADIMIL
NG291
NPC-349
NPC-567 A ten-membered oligopeptide comprising D-arginyl, L-arginyl, L-prolyl, (4R)-4-hydroxy-L-prolyl, glycyl, L-phenylalanyl, L-seryl, D-phenylalanyl, L-phenylalanyl and L-arginine residues joined in sequence.
WIN 64338
[125I]HPP-HOE140
[125I][TYR8]BRADYKININ
[3H]NPC17731
[HYP3,TYR(ME)8]BK
[PHE8,&PSI;(CH2-NH)ARG9]BK
[THI5,8,D-PHE7]BRADYKININ
[TYR8]BRADYKININ
ADAPALENE An adamantane that has formula C28H28O3.
ARSENIC TRIOXIDE
BACLOFEN A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depressant, GABA agonist and muscle relaxant.
CORTICOTROPIN
DIURETIC An agent that promotes the excretion of urine through its effects on kidney function.
EDODEKIN ALFA
ERGOT ALKALOIDS
FLURBIPROFEN A fluorobiphenyl that has formula C15H13FO2.
FREUND'S ADJUVANT
GEMFIBROZIL An aromatic ether that has formula C15H22O3.
IONOMYCIN A very long-chain fatty acid that is docosa-10,16-dienoic acid which is substituted by methyl groups at positions 4, 6, 8, 12, 14, 18 and 20, by hydroxy groups at positions 11, 19 and 21, and by a (2',5-dimethyloctahydro-2,2'-bifuran-5-yl)ethanol group at position 21. An ionophore produced by Streptomyces conglobatus, it is used in research to raise the intracellular level of Ca(2+) and as a research tool to understand Ca(2+) transport across biological membranes.
K 252A
LIDOCAINE The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
MEDICATION
METYROSINE
MONOAMINE OXIDASE INHIBITOR
NORMAL SALINE
NYSTATIN A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptococcus species. The keto-form of nystatin A1.
OPIATE
PROPYLTHIOURACIL
PROTEIN KINASE C INHIBITOR
PROTEIN KINASE INHIBITOR An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST
RNA POLYMERASE INHIBITOR
TYROSINE HYDROXYLASE INHIBITOR
VENLAFAXINE A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group.
VERTEPORFIN
CLODRONATE DISODIUM
COUMARIN
D VITAMIN
ETIDRONIC ACID A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
GM-CSF
ISOFLAVONE
METHIMAZOLE A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen.
MITOMYCIN ANTINEOPLASTIC ANTIBIOTIC
PARICALCITOL
RECOMBINANT BRAIN-DERIVED GROWTH FACTORS
RECOMBINANT COLONY STIMULATING FACTOR
RECOMBINANT PARATHYROID HORMONE-RELATED PROTEIN
SALMON CALCITONIN
BETAINE
AZD5582
BESTATIN METHYL ESTER
BIRINAPANT
BV-6
COMPOUND 20 [PMID: 34432979]
GDC-0152
IAP INHIBITOR HGS1029
LCL161
SM-122
SM-337
TOLINAPANT
XEVINAPANT
7-HYDROXYSTAUROSPORINE
AMMONIUM TRICHLOROTELLURATE
ANTINEOPLASTIC VACCINE
COMPOUND III [PMID: 24080463]
GATAPARSEN SODIUM
INTERFERON BETA-1A
INTERLEUKIN-11
MAVEROPEPIMUT-S
PLEVITREXED
PLICAMYCIN
RAS INHIBITOR
SEPANTRONIUM BROMIDE
SURVAXM
SURVIVIN MRNA ANTAGONIST EZN-3042
SVN53-67/M57-KLH PEPTIDE VACCINE
VALDECOXIB
ACALABRUTINIB
COMPOUND 2 [PMID: 15546730]
COMPOUND 25 [PMID: 31260299]
COMPOUND 31 [PMID: 24915291]
COMPOUND 38 [PMID: 24915291]
COMPOUND 9 [PMID: 26006010]
JNJ-64264681
NEMTABRUTINIB
PRN694
TG100-801
WZ4002
ALAZANINE
BEXAROTENE
CAULIBUGULONE B
CAULIBUGULONE C
CHEMBL:CHEMBL1364172
CHEMBL:CHEMBL1397270
CHEMBL:CHEMBL337173
CHEMBL:CHEMBL463783
CHEMBL:CHEMBL530280
CHEMBL:CHEMBL601140
FENOLDOPAM BROMIDE
FENOLDOPAM MESYLATE
HARMALOL A harmala alkaloid in which the harman skeleton is hydroxy-substituted at C-7 and has been reduced across the 3,4 bond.
HELIOMYCIN
METHOCTRAMINE HYDROCHLORIDE
METHYLENE BLUE CATION
QUINALDINE BLUE
RM-2 GA-68
SALIRASIB
SODIUM TANSHINONE IIA SULFONATE
SOFALCONE
BALOXAVIR
BALOXAVIR MARBOXIL
FAVIPIRAVIR
COMPOUND 2 [PMID: 11934595]
CHEMBL:CHEMBL1321401
CHEMBL:CHEMBL1467165
CHEMBL:CHEMBL1927048
CITALOPRAM A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
DEUCRAVACITINIB
BIIB091
BMX-IN-1
CANERTINIB A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a propenamido group at the 6-position, and a 3-morpholinopropoxy group at the 7-position.
CHEMBL:CHEMBL285063
RITLECITINIB
RITLECITINIB TOSYLATE
ZYBT1
XMP-629
MS363
(10R)-10-METHYL-3-(6-METHYLPYRIDIN-3-YL)-9,10,11,12-TETRAHYDRO-8H-[1,4]DIAZEPINO[5',6':4,5]THIENO[3,2-F]QUINOLIN-8-ONE
ABM-1310
AGERAFENIB
ALPELISIB
ARQ-736
AVUTOMETINIB
AZ628
AZD1208
B-RAF/VEGFR-2 INHIBITOR RAF265
BEROTERKIB ANHYDROUS
BI-2536
BI-3406
BMS-908662
BRAF INHIBITOR
BRAF(V600E) KINASE INHIBITOR RO5212054
BRAFV600/PI3K INHIBITOR ASN003
BRIMARAFENIB
CAPMATINIB
CCT196969
CCT241161
CFT1946
CHEMBL:CHEMBL3326006
CHEMBL:CHEMBL3342187
CHIR-265
CLATURAFENIB
COMMENSAL BACTERIAL STRAIN FORMULATION VE800
COMPOUND 2 [PMID: 26061392]
DABRAFENIB MESYLATE
DEL-22379
DENOSUMAB
DNA-DEPENDENT PROTEIN KINASE-TARGETING SIDNA DT01
DOXORUBICIN LIPOSOME
DUAL IGF-1R/INSR INHIBITOR BMS-754807
E6201
ERK INHIBITOR CC-90003
ERK1/2 INHIBITOR ERAS-007
ERK1/2 INHIBITOR JSI-1187
FICERAFUSP ALFA
FUTIBATINIB
FUTUXIMAB/MODOTUXIMAB MIXTURE
GDC-0879
GSK2636771
GSK329
IAG933
IDELALISIB A member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia.
KO-947
L779450
LGX-806
LUT014
LUVOMETINIB
MAP855
MEK INHIBITOR IMM-1-104
MEK INHIBITOR IMM-6-415
MEK INHIBITOR REC-4881
MEK INHIBITOR RO4987655
MIRDAMETINIB
MITOGEN-ACTIVATED PROTEIN KINASE KINASE INHIBITOR
MK-8353
MOCETINOSTAT
MOSPERAFENIB
NAB-PACLITAXEL
NAPORAFENIB
NAVTEMADLIN
NERATINIB A quinoline compound having a cyano group at the 3-position, a 3-chloro-4-(2-pyridylmethoxy)anilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an ethoxy group at the 7-position.
NST-628
NUTLIN-3 A Nutlin that has formula C30H30Cl2N4O4.
NVP-AEW541
P53-HDM2 INTERACTION INHIBITOR MI-773
PAC-1
PAN-RAF INHIBITOR LY3009120
PAN-RAF INHIBITOR XP-102
PERTUZUMAB
PF-00477736
PF-04217903
PF-07799933
PI3K/BET INHIBITOR LY294002
PICTILISIB
PICTILISIB BISMESYLATE
PILARALISIB
PIMASERTIB
PLIXORAFENIB
PLX-4720
RAF INHIBITOR BDTX-4933
RAF INHIBITOR DCC-3084
RAVOXERTINIB
REFAMETINIB
RG-7256
RINETERKIB
RUXOLITINIB
SAPITINIB
SAR260301
SB590885
SCH772984
SONOLISIB
SPARTALIZUMAB
SY-5609
SZM594
TAK-733
TAZEMETOSTAT
TEMSIROLIMUS
TEMUTERKIB
TGX-221
TINLORAFENIB
TIPIFARNIB
TIVOZANIB
TIZATERKIB
TORIPALIMAB
TUBASTATIN A
TUNLAMETINIB
TW-37
ULIXERTINIB
VORUCICLIB
XL-281
XL888
XP-102
YM-254890
ZM336372
ZSTK474
2-PHENYLQUINOLINE
7-HYDROXY ISOFLAVONE
7-HYDROXYFLAVONE A hydroxyflavonoid that has formula C15H10O3.
CHEMBL:CHEMBL1214407
CHEMBL:CHEMBL12658
CHEMBL:CHEMBL1308677
CHEMBL:CHEMBL1320798
CHEMBL:CHEMBL1404865
CHEMBL:CHEMBL1405979
CHEMBL:CHEMBL1420181
CHEMBL:CHEMBL1481721
CHEMBL:CHEMBL153505
CHEMBL:CHEMBL1574420
CHEMBL:CHEMBL1709259
CHEMBL:CHEMBL273891
CHEMBL:CHEMBL446567
CHEMBL:CHEMBL452954
CHEMBL:CHEMBL484663
CHEMBL:CHEMBL581929
CHEMBL:CHEMBL587620
CHEMBL:CHEMBL588525
CHEMBL:CHEMBL588683
CHEMBL:CHEMBL600315
CHEMBL:CHEMBL66279
GAMMA-FAGARINE
GLABRIDIN An isoflavonoid that has formula C20H20O4.
ILEPCIMIDE
IROFULVEN
PHENAMIL METHANESULFONATE
PHYTOESTROGEN Any compound produced by a plant that happens to have estrogenic activity.
PIDNARULEX
QUARFLOXIN
RIBOFLAVIN D-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
SACITUZUMAB GOVITECAN
SB 204741
TIAPROFENIC ACID An aromatic ketone that is thiophene substituted at C-2 by benzoyl and at C-4 by a 1-carboxyethyl group.
VU0001171
WISTIN
INIPARIB
BAY-299
NI-57
ABBV-744
ACETAMINOPHEN
ALPRAZOLAM A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.
ARV-771
BIC1
BIRABRESIB
BMS-986158
CHEMBL:CHEMBL52030
COMPOUND 36 [PMID: 24000170]
COMPOUND 38 [PMID: 24000170]
COMPOUND 4D [PMID: 21851057]
ET BROMODOMAIN INHIBITOR
GSK852
GW841819X
I-BET151
ME BROMODOMAIN INHIBITOR
MOLIBRESIB
PELABRESIB
RO-6870810
SIM1 single-minded family bHLH transcription factor 1|SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq, Jul 2008]
WNY0824
XD14
ESTAZOLAM A triazolo[4,3-a][1,4]benzodiazepine having a phenyl group at position 6 and a chloro substituent at position 8. A short-acting benzodiazepine with general properties similar to diazepam, it is given by mouth as a hypnotic in the short-term management of insomnia.
(+)-JQ1
AMREDOBRESIB
BIVALENT BRD4 INHIBITOR AZD5153
BRD4 INHIBITOR PLX2853
BZT-7
COMPOUND 1 [PMID: 25408830]
COMPOUND 11H [PMID: 29808961]
COMPOUND 15 [HAY ET AL., 2013]
COMPOUND 2 [PMID: 25408830]
COMPOUND 25AP [PMID: 37796543]
COMPOUND 3 [PMID: 25408830]
COMPOUND 6 [PMID: 30125504]
COMPOUND 7D [PMID: 25703523]
COMPOUND 9 [PMID: 23517011]
CPI-203
DBET6
DUAL BRD4/PLK1 INHIBITOR 23
FEDRATINIB
I-BET282
ISOXAZOLE AZEPINE COMPOUND 3
MIVEBRESIB
MS417
MS436
MZ1
N-METHYL-2-PYRROLIDONE
NHWD-870
PFI-1
REPIBRESIB
TEC4
XD1
XY-06-007
ZAVABRESIB
BI-9564
LP99
TP-472
BI-7273
COMPOUND 50 [PMID: 24313754]
DBRD9
DBRD9-A
I-BRD9
URIC ACID An oxopurine that is the final oxidation product of purine metabolism.
COMPOUND 34 [PMID: 25974391]
OF-1
PFI-4
AC-PHE-TRP-ALA-HIS(&TAU;BZL)-NIP-GLY-ARG-NH2
BAG-1
BAG-2
BANTAG-1
COMPOUND 17C [PMID: 25497965]
COMPOUND 21B [PMID: 12723954]
COMPOUND 22E [PMID: 20167483]
COMPOUND 8A [PMID: 24900283]
COMPOUND 9F [PMID: 24412111]
COMPOUND 9G [PMID: 24412111]
COMPOUND A [PMID: 28324017]
D-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-NAL-NH2
DIMETHYL SHIKONIN OXIME 5A
LICOISOFLAVONE A
MK-5046
MK-7725
ML-18
NMU (104-114)
PHENYLACETYL-ALA,DTRP-PHENTHYLAMIDE
[125I]BANTAG-1
[125I][D-TYR6,&BETA;-ALA11,PHE13,NLE14]BOMBESIN-(6-14)
[D-PHE6,&BETA;-ALA11,PHE13,NLE14]BOMBESIN-(6-14)
[D-TYR6,(R)-APA11,PHE13,NLE14]BOMBESIN-(6-14)
[D-TYR6,APA-4CL11,PHE13,NLE14]BOMBESIN-(6-14)
CCT244747
GAVILIMOMAB
MEPLAZUMAB
ZIRALIMUMAB
ABIVERTINIB
ABIVERTINIB MALEATE
ACALABRUTINIB MALEATE
ATUZABRUTINIB
BIIB068
BIIB129
BIRELENTINIB
BMS-986142
BRANEBRUTINIB
BTK INHIBITOR
BTK INHIBITOR 16 [PMID: 30122225]
BTK INHIBITOR DTRMWXHS-12
BTK INHIBITOR TL-895
CGI1746
CGI560
CHMFL-BTK-11
CINSEBRUTINIB
CNX-774
COMPOUND 36 [PMID: 21958547]
COMPOUND 4G [PMID: 30893553]
COMPOUND 71 [WO2018191577A1]
DD-03-171
EDRALBRUTINIB
ELSUBRUTINIB
EVOBRUTINIB
EXAMPLE A225 [WO2012170976A2]
FENEBRUTINIB
GDC-0834
LFM-A13
LUXEPTINIB
MIDOBRUTINIB
MILREBRUTINIB
MSC-2364447
ORELABRUTINIB
PI3K-DELTA INHIBITOR AMG 319
PIRTOBRUTINIB
POSELTINIB
PROTAC 23 [PMID: 38321747]
PTD10
REMIBRUTINIB
RILZABRUTINIB
RN486
SOFNOBRUTINIB
SPEBRUTINIB
SPEBRUTINIB BESYLATE
SUNVOZERTINIB
TAK-020
TIRABRUTINIB
TOLEBRUTINIB
VECABRUTINIB
ZANUBRUTINIB
ZELEBRUDOMIDE
POM2-C-HMBP
BAY-320
BAY-524
COMPOUND 2-1-1 [PMID: 24900824]
COMPOUND 2-13-1 [PMID: 24900824]
COMPOUND 2-3-1 [PMID: 24900824]
COMPOUND 2-3-2 [PMID: 24900824]
THERAPEUTIC IMMUNE GLOBULIN
ANTITHROMBIN III
ANX-005
C1 ESTERASE INHIBITOR
COMPOUND 28 [PMID: 16460935]
HUMAN C1-ESTERASE INHIBITOR
MANNOSE-BINDING LECTIN
SUTIMLIMAB
AL-78898A
AMY-101
COMPSTATIN
PEGCETACOPLAN
POT-4
AC-RHYPLWR
ALBUTENSIN A
C3A
C3A RECEPTOR AGONIST
CASOXIN C
COMPOUND 17 [PMID: 24257095]
COMPOUND 21 [PMID: 25259874]
COMPOUND 4 [PMID: 25259874]
E7
EU-DTPA-HC3A
FLPLAR
FLTCHAAR
JR14A
ORYZATENSIN
SB290157
SQ007-5
TLQP-21
WWGKKYRASKLGLAR
YSFKPMPLAR
[125I]C3A (HUMAN)
AVACINCAPTAD PEGOL
CROVALIMAB
NOMACOPAN
OLENDALIZUMAB
PEXELIZUMAB
POZELIMAB
TESIDOLUMAB
VILOBELIMAB
ZILUCOPLAN
ZILUCOPLAN SODIUM
ACPHE-ORN-PRO-D-CHA-TRP-ARG
ACT-1014-6470
AVACOPAN
AVDORALIMAB
BM213
BM221
C089
C5A
C5A DES-ARG
CHIPS
DF2593A
DF3016A
DF3966A
EU-DTPA-[SER27, NLE70]HC5A
JPE1375
L-156,602
LACTOMEDIN 1
N-METHYL-PHE-LYS-PRO-D-CHA-CHA-D-ARG-CO2H
N-METHYL-PHE-LYS-PRO-D-CHA-TRP-D-ARG-CO2H
NDT9513727
NDT9520492
PMX205
RIBOSOMAL PROTEIN S19
RPR121154
W54011
[125I]C5A (HUMAN)
C5A HEXAPEPTIDE ANALOGUE
C5APEP
CHIPS-(28-149)
P32 [PMID: 27108698]
P59 [PMID: 27108698]
ACETAZOLAMIDE SODIUM
BENZOLAMIDE
BRINZOLAMIDE
CHLOROTHIAZIDE 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.
COMPOUND 11 [PMID: 41150938]
COMPOUND 5A [PMID: 31287314]
COMPOUND 5B [PMID: 31287314]
DICHLORPHENAMIDE
DORZOLAMIDE 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension.
FERULIC ACID A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.
HISTAMINE A 1H-imidazol-4-yl group substituted at position C-4 by a 2-aminoethyl group.
HISTIDINE
METHAZOLAMIDE
METHOCARBAMOL
PARABEN
PHENOL An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols.
POLMACOXIB
RESORCINOL A benzenediol that is benzene dihydroxylated at positions 1 and 3.
SLC-0111
SULFAMIDE
SULPIRIDE
SULTHIAME
TRICHLORMETHIAZIDE
FLUTICASONE
MAFENIDE
TRIFLUOROMETHANESULFONAMIDE
CYCLOTHIAZIDE
DORZOLAMIDE HYDROCHLORIDE
ETHINAMATE
GUAIACOL
SALVIANOLIC ACID A A stilbenoid that has formula C26H22O10.
ANTI-CA6-DM4 IMMUNOCONJUGATE SAR566658
KAEMPHEROL
CG250 111IN
CG250 177LU
GAMMA-VALEROLACTONE A butan-4-olide that is dihydrofuran-2(3H)-one substituted by a methyl group at position 5. It has been found in the urine samples of humans exposed to n-hexane.
GIRENTUXIMAB
IODINE I 124 GIRENTUXIMAB
ATAGABALIN
BEPRIDIL HYDROCHLORIDE
ELPETRIGINE
GABAPENTIN ENACARBIL A carbamate ester that is the N-[1-(isobutyryloxy)ethoxy]carbonyl derivative of [1-(aminomethyl)cyclohexyl]acetic acid. The prodrug for gabapentin, used for treatment of neuropathic pain and restless legs syndrome.
IMAGABALIN
PHLOROGLUCINOL
PREGABALIN
SULOCTIDIL
TERODILINE HYDROCHLORIDE
C2230
CLEVIDIPINE
CNV-2197944
CNV2197944
LOMERIZINE
NP118809
RALFINAMIDE
SAFINAMIDE
TROX-1
ZICONOTIDE
ZICONOTIDE ACETATE
(-)-(S)-BAYK8644
AMLODIPINE BENZOATE
AMLODIPINE MALEATE
ARVERAPAMIL
AZD1305
BENIDIPINE
CALCISEPTINE
CALCIUM CHANNEL BLOCKER One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
CINNARIZINE
DILTIAZEM HYDROCHLORIDE
DILTIAZEM MALATE
DRONEDARONE HYDROCHLORIDE
FPL64176
IBUTILIDE
ISRADIPINE
LACIDIPINE
LEVAMLODIPINE MALEATE
MANIDIPINE
MEM 1003
MEPIRODIPINE
SZ(+)-(S)-202-791
VERAPAMIL HYDROCHLORIDE
AZIDOPINE A benzamide that has formula C27H26F3N5O5.
BAYK 8644
NI2+
SNX482
6-PRENYLNARINGENIN
ABT-639
ACT-709478
APINOCALTAMIDE
ETHOSUXIMIDE A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
METHSUXIMIDE
ML218
PARAMETHADIONE
PHENSUXIMIDE
SUVECALTAMIDE
TRIMETHADIONE
TTA-A2
ULIXACALTAMIDE
[3H]NGD941
BUXUSEMINE L
CHEMBL:CHEMBL1570199
CHEMBL:CHEMBL526952
CHEMBL:CHEMBL592566
OXATOMIDE
SODIUM BICARBONATE
LERCANIDIPINE
MIROGABALIN
MIROGABALIN BESYLATE
AMIFAMPRIDINE
ANDOLAST
AZIMILIDE An imidazolidine-2,4-dione that has formula C23H28ClN5O3.
BIMAKALIM
CIZOLIRTINE
DALFAMPRIDINE
DIAZOXIDE A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
EPTINEZUMAB
FREMANEZUMAB
GALCANEZUMAB
INCOBOTULINUMTOXINA
RECOMBINANT ACTIVIN
SULCARDINE SULFATE
&ALPHA;-CGRP
&BETA;-CGRP
AC187
ADRENOMEDULLIN
ADRENOMEDULLIN 2/INTERMEDIN
AMLINTIDE
AMYLIN
CAGRILINTIDE
CALCITONIN
CALCITONIN HUMAN
CALCITONIN SALMON
CALCITONIN-(8-32) (SALMON)
DAVALINTIDE
HUMAN CALCITONIN
KBP-066
KBP-088
NN1213
PRAMLINTIDE
PRAMLINTIDE ACETATE
SMC021
[125I]CALCITONIN
[125I]CALCITONIN (SALMON)
ATOGEPANT
BI-44370
CALCITONIN GENE-RELATED PEPTIDE
ERENUMAB
MK-3207
MK3207
OLCEGEPANT
RIMEGEPANT
RIMEGEPANT SULFATE
TELCAGEPANT
UBROGEPANT
ZAVEGEPANT
ZAVEGEPANT HYDROCHLORIDE
APRINDINE
BENZIODARONE
PRENYLAMINE
VACCINIA VACCINE
ACENOCOUMAROL
AZD-1080
LY2090314
RIMACALIB
COMPOUND 15B [PMID: 18334293]
COMPOUND 27 [PMID: 18337095]
MELK-TI
STO609
LERIDISTIM
CALPEPTIN An amino acid amide that has formula C20H30N2O4.
GC-376
MITUCAPISTAT
UAWJ9-36-3
COMPOUND 19 [PMID: 8831774]
PEGINTERFERON ALFA-2B
BIIB021
BMS PYRAZOLE INHIBITOR 7F
COMPOUND 17F [PMID: 19632837]
COMPOUND 43 [PMID: 34781683]
EOSIN
ICARM1
MS023
MS049
SGC2085
COMPOUND 26 [PMID: 34543009]
BELNACASAN
BERKELEYACETAL A
BERKELEYACETAL B
BERKELEYACETAL C
BERKELEYAMIDE B
BERKELEYAMIDE C
BERKELEYDIONE
BERKELEYTRIONE
CHEMBL:CHEMBL415893
DIACETYLRHEIN
EMRICASAN
ISOBOLDINE
M826
NIVOCASAN
PRALNACASAN
URACIL 20
VERMISTATIN
VRT-043198
Z-YVAD-FMK
GRASSYSTATIN A
CHEMBL:CHEMBL265439
COMPOUND 4 [PMID: 12408711]
SPERMINE A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism.
Z-VDVAD-FMK
1,4-DICHLOROBENZENE
AC-DEVD-CHO
AZ10417808
CHEMBL:CHEMBL1210769
CHEMBL:CHEMBL375563
CHEMBL:CHEMBL376616
CHEMBL:CHEMBL378903
CHEMBL:CHEMBL412603
CHEMBL:CHEMBL483849
CHEMBL:CHEMBL560532
CHEMBL:CHEMBL584668
IDRONOXIL
KOBOPHENOL A
PAC1
PETCM
PHATHALIMIDE
TELEOCIDIN B
XANTHOANGELOL B
Z-DEVD-FMK
Z-DQMD-FMK
CASP 4 INHIB
Z-WEHD-FMK
AC-VEID-CHO
ALOSETRON HYDROCHLORIDE
CHEMBL:CHEMBL1370674
CHEMBL:CHEMBL176599
CHEMBL:CHEMBL445304
CHEMBL:CHEMBL478754
GAMMA-LINOLENIC ACID A C18, omega-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.
METHYLERGONOVINE MALEATE
METHYSERGIDE MALEATE
Z-VEID-FMK
CHEMBL:CHEMBL516616
IRL 2500
ISATIN SULFONAMIDE 34 [PMID: 11384246]
CONATUMUMAB
Z-IETD-FMK
Z-LEHD-FMK
(R)-2H [PMID:19625189]
2-METHYL-3-PHENETHYL-3H-PYRIMIDIN-4-ONE
AC265347
AMINOGLYCOSIDE ANTIBIOTIC
ASP7991
ATF-936
ATF936
AXT-914
AXT914
CALHEX 231
CALINDOL
CINACALCET
CINACALCET HYDROCHLORIDE
COMPOUND (S)-3H [PMID: 15686947]
COMPOUND 18C [PMID:19143533]
ENCALERET
ENCALERET SULFATE
ETELCALCETIDE
ETELCALCETIDE HYDROCHLORIDE
EVOCALCET
GOSICALCETIDE
NANOBODY NB32
NANOBODY NB4
NPS 2143
NPS-2143
PAMIDRONATE DISODIUM
PARATHYROID HORMONE
RONACALERET
SB-423562
STRONTIUM RANELATE
TECALCET
TECALCET HYDROCHLORIDE
UPACICALCET
DINOPROSTONE
HC-056456
NNC55-0396
PGF1&ALPHA;
EPERISONE A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.
TOLPERISONE
&ALPHA;-ERGOCRYPTINE
CETIRIZINE HYDROCHLORIDE
CYTARABINE HYDROCHLORIDE
ERGOCORNINE
AVAPRITINIB
ENTOSPLETINIB
MIDOSTAURIN
P505-15
QUIZARTINIB
RECOMBINANT INTERLEUKIN-2
SU11274
NX-1607
AMINOOXYACETIC ACID
BENSERAZIDE
VITAMIN B6
5'-GUANIDINONALTRINDOLE
APTIGANEL
CAMBINOL
CARISOPRODOL A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
CHEMBL:CHEMBL119878
CHEMBL:CHEMBL1627202
CHEMBL:CHEMBL189382
CHEMBL:CHEMBL538542
CLOFAZIMINE
CYSTAMINE An organic disulfide obtgained by oxidative dimerisation of cysteamine.
CYSTAMINE HYDROCHLORIDE
DIAMIDE
DIZOCILPINE An organic tricyclic compound that has formula C16H15N.
EXISULIND
FLUPHENAZINE HYDROCHLORIDE
FLUPIRTINE
GUAIAZULEN
HYDROXYAMINE
IPA-3
ISOXANTHOPTERIN
KYNURENIC ACID A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
ML 10302
OXOLINIC ACID
PD 169316
PROFENAMINE
RUFINAMIDE
SB 206553 A pyrroloindole that has formula C17H16N4O.
SB202190
TAXIFOLIN
TETRADECYLTHIOACETIC ACID
TETRYDAMINE
TRIMETHOPRIM An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
TRIMIPRAMINE A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.
WIN55212-2
XCT790
ANASTROZOLE A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position.
LETROZOLE A triazole that has formula C17H11N5.
PRALSETINIB
SELPERCATINIB
STREPTOGRAMIN A
A-71378
CCK-33
CCK-39
CCK-58
CE-326597
CERULETIDE A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.
CERULETIDE DIETHYLAMINE
DEXLOXIGLUMIDE
GLAXO-11P
GW-5823
JMV180
JNJ-17156516
LINTITRIPT
PD-170292
PROGLUMIDE
SINCALIDE
SR146131
[125I]DTYR-GLY-[(NLE28,31)CCK-26-33
[3H]DEVAZEPIDE
AG-041R
BENZODIAZEPINE A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.
CCK-4
CI-988
DESULFATED CHOLECYSTOKININ-8
DESULFATED GASTRIN-14
DESULFATED GASTRIN-17
DESULFATED GASTRIN-34
DESULFATED GASTRIN-71
GASTRIN-14
GASTRIN-34
GASTRIN-71
GV150013
ITRIGLUMIDE
JNJ-26070109
L-365260 A benzodiazepine that has formula C24H22N4O2.
L-740093
LORGLUMIDE
LY-288513
MORPHINE SULFATE
NETAZEPIDE
PD-135158
PENTAGASTRIN
SPIROGLUMIDE
TETRONOTHIODIN
YM-022
Z-360
[125I]-BDZ2
[125I]GASTRIN
[3H]GASTRIN
[3H]L365260
BERTILIMUMAB
TNF-ALPHA
RECOMBINANT CHEMOKINE
RECOMBINANT RANTES
DINITROCHLOROBENZENE
POLY IC
RECOMBINANT INTERLEUKIN-17
RECOMBINANT TUMOR NECROSIS FACTOR-BETA
TOPICAL CORTICOSTEROID
ACORAFLOXACIN
ALATROFLOXACIN MESYLATE
BESIFLOXACIN HYDROCHLORIDE
CIPROFLOXACIN HYDROCHLORIDE
DELAFLOXACIN MEGLUMINE
FINAFLOXACIN
GARENOXACIN MESYLATE
GATIFLOXACIN ANHYDROUS
GEMIFLOXACIN MESYLATE
GEPOTIDACIN
GREPAFLOXACIN HYDROCHLORIDE
IMMUNOTHERAPEUTIC AGENT
LEVOFLOXACIN An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase
MOXIFLOXACIN HYDROCHLORIDE
NADIFLOXACIN
NEMONOXACIN
NORFLOXACIN A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
OZENOXACIN
PEFLOXACIN
PRADOFLOXACIN
RECOMBINANT MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA
RIFAQUIZINONE
SITAFLOXACIN
TROVAFLOXACIN
TROVAFLOXACIN MESYLATE
ZABOFLOXACIN
ZOLIFLODACIN
BINDARIT
CARLUMAB
EMAPTICAP PEGOL
RS-504393
GSK3050002
RECOMBINANT ALPHA CHEMOKINE
RECOMBINANT HUMAN MACROPHAGE INFLAMMATORY PROTEIN-1 BETA
RECOMBINANT LYMPHOTOXIN BETA
RECOMBINANT BETA CHEMOKINE
RECOMBINANT EOTAXIN
RECOMBINANT FRACTALKINE
RECOMBINANT HUMAN 6CKINE
ADJUVANT
NAGRESTIPEN
RECOMBINANT OX40 LIGAND
RECOMBINANT INTERLEUKIN-8
ACRIDINE
OCAPERIDONE
PAMREVLUMAB
THERAPEUTIC INTERLEUKIN-9
SELICICLIB
BRICICLIB
CHEMOPREVENTIVE AGENT
RONICICLIB
CDK INHIBITOR SNS-032
FADRACICLIB
LUNRESERTIB
TASELISIB
RETROVECTOR ENCODING MUTANT ANTI-CYCLIN G1
AZD4818
BMS-817399
BP-CCL3
BX 471
CCL13 chemokine (C-C motif) ligand 13|This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]
CCL14 chemokine (C-C motif) ligand 14|This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]
CCL15 chemokine (C-C motif) ligand 15|This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)|This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
CCL23 chemokine (C-C motif) ligand 23|This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
CCL3 chemokine (C-C motif) ligand 3|This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
CCL4 chemokine (C-C motif) ligand 4|The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]
CCL5 chemokine (C-C motif) ligand 5|This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
CCL7 chemokine (C-C motif) ligand 7|This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]
CCL8 chemokine (C-C motif) ligand 8|This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
CCX-354
CCX354
CHEMBL:CHEMBL2205805
COMPOUND 2B-1 [PMID: 12614873]
CP-481,715
FLU-CCL3
MLN-3897
UCB35625
VMIP-II
[125I]CCL2 (HUMAN)
[125I]CCL3 (HUMAN)
[125I]CCL5 (HUMAN)
[125I]CCL7 (HUMAN)
[125I]CCL8 (HUMAN)
BI-6901
CCL27 chemokine (C-C motif) ligand 27|This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
CCL28 chemokine (C-C motif) ligand 28|This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
ALITRETINOIN
AZD2423
BMS-681
BMS-741672
BMS-753426
BMS-813160
CCL11 chemokine (C-C motif) ligand 11|This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
CCL16 chemokine (C-C motif) ligand 16|This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]
CCL2 chemokine (C-C motif) ligand 2|This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
CCL24 chemokine (C-C motif) ligand 24|This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008]
CCL26 chemokine (C-C motif) ligand 26|This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]
CCR2-RA-[R]
CENICRIVIROC
CHEMBL:CHEMBL41275
COMPOUND 39 [PMID: 31742400]
GSK COMPOUND 34
HIV-TAT
ILACIRNON
INCB3284
INCB8761
JNJ-27141491
JNJ-41443532
MC148R
MK-0812
PF-04634817
PIMAGEDINE
PLOZALIZUMAB
RS-102895
RS-136270
SB-282241
TAK-779
TEIJIN-LEAD_CMP_5
VCCL4
AZD3778
BMS COMPOUND 87B
CXCL10 chemokine (C-X-C motif) ligand 10|This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]
CXCL9 chemokine (C-X-C motif) ligand 9|This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]
GW766994
LAZUCIRNON
MET-CK&BETA;7
RO116-4875/608
RO116-9132/238
RO320-2947/001
RO330-0802/001
SB328437
TPI-ASM8
YM-355179
[125I]CCL11 (HUMAN)
[3H]BANYU (I)
AUTOLOGOUS CCR4-CD30CAR-CD28-CD3ZETA-EXPRESSING T-LYMPHOCYTES
AZD1678
AZD2098
CCL17 chemokine (C-C motif) ligand 17|This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]
CCL22 chemokine (C-C motif) ligand 22|This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]
COMPOUND 31 [PMID: 31259550]
COMPOUND 8IC [PMID: 19081254]
FLX475
GSK-2239633
GSK2239633A
MOGAMULIZUMAB
VMIP-III
ZELNECIRNON
[125I]CCL17 (HUMAN)
[125I]CCL27 (HUMAN)
ANTI-HIV-1 LENTIVIRAL VECTOR-EXPRESSING SH5/C46 CAL-1
APLAVIROC
AZD5672
CCR5 ANTAGONIST 34
CCR5 MAB
CCR5MAB004
CENICRIVIROC MESYLATE
E913
GLATIRAMER
HGS-1025
INCB-9471
LERONLIMAB
MARAVIROC
PF-232798
R5-HIV-1 GP120
TAK-220
VICRIVIROC
VICRIVIROC MALEATE
[125I]CCL4 (HUMAN)
[3H]ANCRIVIROC
[3H]MARAVIROC
BETA-DEFENSIN 4A
CCL20 chemokine (C-C motif) ligand 20|This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
CCL20-SEAP(HIS)6
PF-07054894
[125I]CCL20 (HUMAN)
CCL21B
[125I]CCL19 (HUMAN)
[125I]CCL21 (HUMAN)
CCL1 chemokine (C-C motif) ligand 1|This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]
VMCC-I
VMIP-I
ZK 756326
[125I]CCL1 (HUMAN)
COMPOUND 24 [PMID: 26987013 ]
MLN3126
VERCIRNON
[125I]CCL25 (HUMAN)
ATIBUCLIMAB
IC14
VB-201
AFM-11
ALLOGENEIC ANTI-CD19-CAR-CD28-IL-15-EXPRESSING NATURAL KILLER T-CELLS
AMG-729
ANTI-CD19 CAR T CELLS PREPARATION
ANTI-CD19 CAR T-CELLS XLCART001
ANTI-CD19 CAR-T CELLS
ANTI-CD20 CAR T CELLS PREPARATION
AUTO3
AUTOLOGOUS ANTI-CD19 CAR T-CELLS IM19
AUTOLOGOUS ANTI-CD19 CAR-EXPRESSING T-LYMPHOCYTES CLIC-1901
AUTOLOGOUS ANTI-CD19 CAR-T CELLS TBI-1501
AUTOLOGOUS ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR T-CELLS C-CAR011
AUTOLOGOUS ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR T-CELLS SJCAR19
AUTOLOGOUS ANTI-CD19CAR-4-1BB-CD3ZETA-EGFRT-EXPRESSING T LYMPHOCYTES
AUTOLOGOUS CD19 CAR-EXPRESSING CD4+/CD8+ T-CELLS MB-CART19.1
AUTOLOGOUS CD19CAR-CD28-CD137/CD27/CD3ZETA-ICASP9-EXPRESSING T-LYMPHOCYTES
AXICABTAGENE CILOLEUCEL
AZERCABTAGENE ZAPRELEUCEL
BREXUCABTAGENE AUTOLEUCEL
CD19-TARGETED CAR T2 CELLS
CD19CAR-CD3ZETA-4-1BB-EXPRESSING ALLOGENEIC T-LYMPHOCYTE CELLS
COLTUXIMAB RAVTANSINE
DEGLYCOSYLATED RICIN A CHAIN-CONJUGATED ANTI-CD19/ANTI-CD22 IMMUNOTOXINS
DENINTUZUMAB
DENINTUZUMAB MAFODOTIN
DUVORTUXIZUMAB
JCAR014
LISOCABTAGENE MARALEUCEL
LONCASTUXIMAB TESIRINE
MDX-1342
OBECABTAGENE AUTOLEUCEL
OBEXELIMAB
ONCOLYSIN B
RELMACABTAGENE AUTOLEUCEL
TAFASITAMAB
TAPLITUMOMAB PAPTOX
TISAGENLECLEUCEL
VADACABTAGENE LERALEUCEL
ANTI-THYMOCYTE GLOBULIN
AH10-7
RGI-7000
ALEFACEPT
SIPLIZUMAB
SAMALIZUMAB
ANTI-CD22 CAR T CELLS PREPARATION
ANTI-CD22 CAR-EXPRESSING T LYMPHOCYTES
BECTUMOMAB
BL22
EPRATUZUMAB
EPRATUZUMAB 90Y
EPRATUZUMAB-CYS-TESIRINE
IMMURAIT-LL2
INOTUZUMAB
MONO-DGA-RFB4
MOXETUMOMAB PASUDOTOX
OSPA LIPOPROTEIN
PINATUZUMAB VEDOTIN
YTTRIUM Y 90 EPRATUZUMAB
YTTRIUM Y 90 EPRATUZUMAB TETRAXETAN
MUROMONAB-CD3
ONTUXIZUMAB
CD70 CD70 molecule|The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
VARLILUMAB
ADEBRELIMAB
ANTI-LAG-3/PD-L1 BISPECIFIC ANTIBODY FS118
ANTI-PD-L1 MONOCLONAL ANTIBODY FAZ053
ANTI-PD-L1 MONOCLONAL ANTIBODY MDX-1105
BETIFISOLIMAB
BINTRAFUSP ALFA
CA-170
COSIBELIMAB
DANBURSTOTUG
ENVAFOLIMAB
ERFONRILIMAB
INCB-086550
LODAPOLIMAB
PACMILIMAB
PENPULIMAB
PIDILIZUMAB
SOCAZOLIMAB
SUGEMALIMAB
TISLELIZUMAB
8H9 131I
ENOBLITUZUMAB
IFINATAMAB DERUXTECAN
IODINE I 124 OMBURTAMAB
OBRINDATAMAB
OMBURTAMAB I-131
BELATACEPT
BENZODEPA
BISPECIFIC ANTIBODY
GUSPERIMUS TRIHYDROCHLORIDE
INTERLEUKIN-12 GENE
LULIZUMAB PEGOL
PHOSPHATIDYLINOSITIDE 3-KINASE INHIBITOR
TGN-1412
ACTINIUM AC 225 LINTUZUMAB
ANTI-CD33 CAR T-CELLS
AVE-9633
BI-836858
ELUVIXTAMAB
EMERFETAMAB
GEMTUZUMAB
LINTUZUMAB
M195
ONCOLYSIN M
VADASTUXIMAB TALIRINE
VIXTIMOTAMAB
AUTOLOGOUS BONE MARROW-DERIVED CD34/CXCR4-POSITIVE STEM CELLS AMR-001
BOVINE PITUITARY EXTRACT
FLUORODEOXYGLUCOSE F18
ABT-510
PEPTIDE 5A
THROMBOSPONDIN 1
BI-836826
LILOTOMAB
NARATUXIMAB EMTANSINE
OTLERTUZUMAB
ANTI-CD38 CAR T CELLS PREPARATION
DARATUMUMAB
FELZARTAMAB
HUMAX-IL15
ISATUXIMAB
MEZAGITAMAB
MK-0159
ANTI-CD3 MONOCLONAL ANTIBODY
CATUMAXOMAB
ELRANATAMAB
EPCORITAMAB
FBT-A05
FLOTETUZUMAB
FORALUMAB
GLOFITAMAB
IMC-GP100
MOSUNETUZUMAB
ODRONEXTAMAB
OTELIXIZUMAB
SOLITOMAB
TALQUETAMAB
TARLATAMAB
TECLISTAMAB
VISILIZUMAB
AX-024
ERTUMAXOMAB
HOKT3
LINVOSELTAMAB
MEDI-565
PF-07062119
RESIMMUNE
TEPLIZUMAB
TEPODITAMAB
XALURITAMIG
ZWB67
ANTI-GPA33/CD3 MONOCLONAL ANTIBODY MGD007
TEBENTAFUSP
CEDELIZUMAB
CLENOLIXIMAB
IBALIZUMAB
KELIXIMAB
PRILIXIMAB
SEMZUVOLIMAB
TREGALIZUMAB
TRX-1
TRX1
VRC-01LS
ZANOLIMUMAB
ALDESLEUKIN
AUTOLOGOUS PROSTATE CANCER ANTIGEN-EXPRESSING DENDRITIC CELL VACCINE BPX-101
BLESELUMAB
CD40 LIGAND
CDX-1140
DACETUZUMAB
GILORALIMAB
ISCALIMAB
LUCATUMUMAB
MITAZALIMAB
MONOCLONAL ANTIBODY SGN-14
PG-102
RAVAGALIMAB
RECOMBINANT CD40-LIGAND
SELICRELUMAB
SOTIGALIMAB
TENELIXIMAB
TETANUS TOXOID VACCINE
ANTI-CD40 MONOCLONAL ANTIBODY CHI LOB 7/4
ANTI-CD40/ANTI-MESOTHELIN BISPECIFIC ANTIBODY ABBV-428
DAPIROLIZUMAB PEGOL
DAZODALIBEP
RUPLIZUMAB
TEGOPRUBART
TORALIZUMAB
BIVATUZUMAB
BIVATUZUMAB MERTANSINE
HYALURONIC ACID A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates.
PF-03475952
ANTI-CD47 MONOCLONAL ANTIBODY CC-90002
EVORPACEPT
LIGUFALIMAB
MAGROLIMAB
ONTORPACEPT
HEXAMETHYLENE BISACETAMIDE
TELIMOMAB ARITOX
ZOLIMOMAB ARITOX
ALEMTUZUMAB
ALEMTUZUMAB BETA
GATRALIMAB
COXSACKIEVIRUS A21
INTERFERON BETA-1B
ITOLIZUMAB
ONCOLYSIN CD6
ANTINEOPLASTIC ANTIBIOTIC
TOCILIZUMAB
ANTI-CD7 CAR T CELLS PREPARATION
ANTI-CD27L ANTIBODY-DRUG CONJUGATE AMG 172
ANTI-CD70 ANTIBODY-DDRUG CONJUGATE MDX-1203
CUSATUZUMAB
MDX-1411
SGN-CD70A
VORSETUZUMAB
VORSETUZUMAB MAFODOTIN
MILATUZUMAB
MGD-010
ABATACEPT
DNA VACCINE
GALIXIMAB
PICIBANIL
TOREMIFENE
VIAGENPUMATUCEL-L
RECOMBINANT NERVE GROWTH FACTOR
ATTENUATED CORYNEBACTERIUM PARVUM
EMFILERMIN
RECOMBINANT INTERLEUKIN-16
RECOMBINANT INTERLEUKIN-5
THERAPEUTIC STEROID HORMONE
CEDAZURIDINE
DOXECITINE
TETRAHYDROURIDINE
P6949
CHEMBL:CHEMBL1172911
CHEMBL:CHEMBL1270061
CHEMBL:CHEMBL1331754
CHEMBL:CHEMBL1333982
CHEMBL:CHEMBL1408031
CHEMBL:CHEMBL1414990
CHEMBL:CHEMBL1481453
CHEMBL:CHEMBL1600564
CHEMBL:CHEMBL2003658
CHEMBL:CHEMBL2059067
CHEMBL:CHEMBL2059068
CHEMBL:CHEMBL2059074
CHEMBL:CHEMBL2059274
CHEMBL:CHEMBL357170
CHEMBL:CHEMBL471004
CHEMBL:CHEMBL507159
SODIUM MOLYBDATE
CHEMBL:CHEMBL554475
CHEMBL:CHEMBL562095
CHEMBL:CHEMBL563777
GONADORELIN
SECRAMINE A
SECRAMINE B
COMPOUND 11D [DOI: 10.1039/C0MD00194E]
RKI-1447
(7S)-2-(2-AMINOPYRIMIDIN-4-YL)-7-(2-FLUOROETHYL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
BMS-863233
COMPOUND 1 [PMID: 24793884]
COMPOUND 18 [PMID: 20873740]
COMPOUND 2 [PMID: 22560567]
COMPOUND 74 [PMID: 24793884]
COMPOUND 77 [PMID: 24793884]
MONZOSERTIB
NMS-1116354
RXDX-103
SIMUROSERTIB
XL413
FOSBRETABULIN TROMETHAMINE
PANCREATIC PROTEOLYTIC ENZYMES
RECOMBINANT HEPATOCYTE GROWTH FACTOR
SQUALAMINE LACTATE
ADH-1
PF-03732010
PF-06671008
FX06
(2R)-2-({9-(1-METHYLETHYL)-6-[(4-PYRIDIN-2-YLBENZYL)AMINO]-9H-PURIN-2-YL}AMINO)BUTAN-1-OL
(RS)-ROSCOVITINE
(S)-CR8
2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)ETHANOL
6-BROMOINDIRUBIN-3'-OXIME
6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
AG-24322
ALSTERPAULLONE 2-CYANOETHYL
AMINOPURVALANOL A
ARUNCIN B
ASNUCICLIB
AT-7519
AZD5438
BMS-265246
BMS-387032
BOHEMINE
BS-194
CDK INHIBITOR 4.35
CDK1 INHIBITOR
CDK1/2/4 INHIBITOR AG-024322
CDK1/5 INHIBITOR
CDK2 INHIBITOR III
CDK4 INHIBITOR
CGP74514A
CHEMBL:CHEMBL1082552
CLOFIBRATE A carboxylic ester that is the ethyl ester of clofibric acid.
COMPOUND 5G [PMID: 36385925]
COMPOUND 9B [PMID: 18986805]
K-00546
KINASE INHIBITOR 2 [PMID: 30199702]
LADUVIGLUSIB
MILCICLIB
MKC-1
PATULIN A furopyran and lactone that is 2H-pyran-3(6H)-ylidene)acetic acid which is syubstituted by hydroxy groups at positions 2 and 4 and in which the hydroxy group at position 4 has condensed with the carboxy group to give the corresponding bicyclic lactone. A mycotoxin produced by several species of Aspergillus and Penicillium, it has antibiotic properties but has been shown to be carcinogenic and mutagenic.
PHA-793887
QR-6401
R547
RGB-286638
RIVICICLIB
RO3306
SAMURACICLIB
TANUXICICLIB
THAL-SNS-032
ZOTIRACICLIB
CDK12 INHIBITOR 2
YJZ5118
CCT251545
COMPOUND 51 [MALLINGER ET AL., 2016]
CORTISTATIN A
JH-VIII-49
PEXIDARTINIB
SEL120-34A FREE BASE
ALOISINE
AZD8421
BS-181
BX-912
CDK INHIBITOR AT7519
CDK4 INHIBITOR II
CDK4 INHIBITOR III
CHEMBL:CHEMBL365617
CHEMBL:CHEMBL373822
CHEMBL:CHEMBL402915
CHEMBL:CHEMBL494107
CHEMBL:CHEMBL557670
COMPOUND 17 [PMID: 38325398]
COMPOUND 3 [PMID: 19097791]
CULMERCICLIB
EBVACICLIB
ERIBULIN
INDOLE-3-CARBINOL
ISTISOCICLIB
JNK INHIBITOR VIII
MK-8776
OLOMOUCINE
PURINE ANTAGONIST
PURVALANOL A A purvalanol that has formula C19H25ClN6O.
PURVALANOL B
SNS-032
TAGTOCICLIB
TRILACICLIB
UCN-01
VUSTANACICLIB
ANTINEOPLASTIC AGENT A substance that inhibits or prevents the proliferation of neoplasms.
APREMILAST
ATIRMOCICLIB
BIREOCICLIB
BSJ-03-123
BSJ-03-204
BSJ-04-132
CHEMBL:CHEMBL1956069
CIMPUCICLIB
CP-10
CROZBACICLIB
DALPICICLIB
FASCAPLYSIN
INIXACICLIB
LEROCICLIB
NARAZACICLIB
PRT3645
RIBOCICLIB SUCCINATE
RO-0505124
SOMATROPIN (RECOMBINANT DNA ORIGIN)
TIBREMCICLIB
TRILACICLIB DIHYDROCHLORIDE
ULECACICLIB
CHEMBL:CHEMBL1276446
CHEMBL:CHEMBL261692
CDK/CRK INHIBITOR
LY3405105
MEVOCICLIB
MOCACICLIB
ZELTOCICLIB
COMPOUND 20 [BERGERON ET AL., 2016]
DORAMAPIMOD
DS96432529
JH-XI-10-02
ATUVECICLIB
CDK9 INHIBITOR 1-7A-B1
CDK9 PROTAC C3
ENITOCICLIB
KI-CDK9D-32
NVP-2
ZEMIRCICLIB
SITAGLIPTIN A triazolopyrazine that exhibits hypoglycemic activity.
URMC-099
GANAXOLONE
ANTIMETABOLITE
CASPASE INHIBITOR
DEXTRAN SULFATE SODIUM
DIAZIQUONE
FARNESYL TRANSFERASE INHIBITOR
NIMUSTINE An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-amino-2-methylpyrimidin-5-ylmethyl] group. An antineoplastic agent especially effective against malignant brain tumors.
PENTETIC ACID A pentacarboxylic acid that has formula C14H23N3O10.
SODIUM SALICYLATE An organic molecular entity that has formula C7H5O3.Na.
HMN-214
IMMUNE CHECKPOINT INHIBITOR
PF-04691502
POLO-LIKE KINASE 1 INHIBITOR GSK461364
DRUGSATFDA.NDA:008378
TEGAFUR
ARCITUMOMAB
90Y-CT84.66
ANTI-CEA CAR T CELLS
ANTI-CEA/ANTI-HSG BISPECIFIC MONOCLONAL ANTIBODY TF2
CALCIUM GLUCONATE
CARCINOEMBRYONIC ANTIGEN PEPTIDE 1-6D VIRUS-LIKE REPLICON PARTICLES VACCINE
CARCINOEMBRYONIC ANTIGEN-EXPRESSING MEASLES VIRUS
CERGUTUZUMAB AMUNALEUKIN
COL-1 Col-1 is an Arabidopsis ecotype and the original AIS donation of Columbia (isolate 5-13) from George Redei.
GI-6207
LABETUZUMAB
LABETUZUMAB GOVITECAN
MONOCLONAL ANTIBODY 3H1 ANTI-IDIOTYPE VACCINE
T84.66
TUSAMITAMAB RAVTANSINE
YTTRIUM Y 90 ANTI-CEA MONOCLONAL ANTIBODY CT84.66
YTTRIUM Y 90 LABETUZUMAB
OICR-9429
NVS-1
BUCELIPASE ALFA
TAUROCHOLIC ACID A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
ERDOSTEINE
SIVELESTAT
TELAPREVIR
ELAFIN
GSK-923295
BRIVANIB
NVP 231
ELDACIMIBE
FESOTERODINE
GR148672X
PACTIMIBE
REMIMAZOLAM
SOFOSBUVIR
ANACETRAPIB
CHEMBL:CHEMBL1086624
DRL-17822
EVACETRAPIB
MK-8262
OBICETRAPIB
ROCACETRAPIB
TORCETRAPIB A (trifluoromethyl)benzene that has formula C26H25F9N2O4.
COMPOUND 51 [PMID: 19743866]
IPTACOPAN
IPTACOPAN HYDROCHLORIDE
COMPOUND 2 [PMID: 28621538]
DANICOPAN
EXAMPLE 373 [WO2012093101]
LAMPALIZUMAB
CR2-FH FUSION PROTEIN TT30
MENINGOCOCCAL GROUP B VACCINE
(R)-BPO-27
ABBV-3221
BAMOCAFTOR
CBIQ
CFTRINH-172
COMPOUND 16D [PMID: 36573286]
CYSTEAMINE HYDROCHLORIDE
DEUTIVACAFTOR
ELEXACAFTOR
GALICAFTOR
GATX1
GLPG-1837
GLPG-2737
GLPG1837
GLPG2737
GLYH-101
ICENTICAFTOR
IOWH-032
IVACAFTOR
LUMACAFTOR
NAVOCAFTOR
NS004
OLACAFTOR
PHENYLGLYCINE-01
ROFLUMILAST
SCRIPTAID
SULFONAMIDE-01
TEZACAFTOR
TEZACAFTOR AND IVACAFTOR
UCCF-029
UCCF-339
UCCF-853
VANZACAFTOR
CHEMBL:CHEMBL1446150
IBOCTADEKIN
BAICALIN The glycosyloxyflavone which is the 7-O-glucuronide of baicalein.
COMPOUND 20 [PMID: 37666112]
PF‐06928215
HUMAN MONOCLONAL ANTIBODY B11-HCG BETA FUSION PROTEIN CDX-1307
GOSSYPOL ACETIC ACID
ACAMPROSATE CALCIUM
AZD7762
BEN-28010
CCT241533
CCT245737
CHEMBL:CHEMBL506048
CHIR-124
COMPOUND 25 [PMID: 17935989]
COMPOUND 33 [PMID: 19364658]
GDC-0425
ISOGRANULATIMIDE
PF-477736
PREXASERTIB
RABUSERTIB
RG-7602
RG-7741
SB 218078
SCH-900776
XL-844
XL844
CHK2 INHIBITOR II
COMPOUND 7F [PMID: 29283260]
GLPG4716
CHOLINE KINASE ALPHA INHIBITOR TCD-717
RSM-932A
VARENICLINE
(&PLUSMN;)YM796
(-)-YM796
(S)-DIMETINDENE
4-DAMP
AC-42
ACECLIDINE
ACLIDINIUM
AFACIFENACIN
AFDX384
ALCURONIUM
ALEXA-488-TELENZEPINE
AQ-RA 741
ARECAIDINE PROPARGYL ESTER
ARECOLINE A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
ASM-024
ATROPINE SULFATE
AZD-6088
AZD6088
BENZOQUINAZOLINONE 12
BENZQUINAMIDE
BENZTROPINE
BENZTROPINE MESYLATE
BETHANECHOL The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
BIPERIDEN
BIPERIDEN HYDROCHLORIDE
BIPERIDEN LACTATE
BLARCAMESINE
BODIPY-PIRENZEPINE
BQCA
BRUCINE N-OXIDE
BUCLIZINE
CARBAMOYLCHOLINE
CARBINOXAMINE An organochlorine compound that is 2-(4-chlorobenzyl)pyridine in which one of the benzylic hydrogens is substituted by 2-(dimethylamino)ethoxy group. It is an ethanolamine-type antihistamine, used as its maleate salt for treating hay fever, as well as mild cases of Parkinson's disease.
CEVIMELINE
CEVIMELINE HYDROCHLORIDE
CLIDINIUM The ester resulting from formal condensation of benzilic acid and 3-hydroxy-1-methyl-1-azoniabicyclo[2.2.2]octane. It is used, generally as the bromide, for the symptomatic treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.
CLIDINIUM BROMIDE
CY3B-TELENZEPINE
CYCLOPENTOLATE A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.
CYCRIMINE
CYCRIMINE HYDROCHLORIDE
DARIFENACIN
DAROTROPIUM BROMIDE
DICYCLOMINE HYDROCHLORIDE
DIPHEMANIL METHYLSULFATE The alkene resulting from the formal Wittig olefination of benzophenone and 1,1-dimethyl-4-bromopiperidinium methylsulfate. A quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids, saliva and sweat, It is used topically in the treatment of hyperhidorsis (excessive sweating).
DIPHENIDOL
DIPHENIDOL HYDROCHLORIDE
DOTHIEPIN
FLAVOXATE A carboxylic ester resulting from the formal condensation of 3-methylflavone-8-carboxylic acid with 2-(1-piperidinyl)ethanol.
FURTRETHONIUM IODIDE
G&OUML; 7874
GLYCOPYRRONIUM
GLYCOPYRRONIUM TOSYLATE
HEXAHYDROSILADIFENIDOL
HEXOCYCLIUM METHYLSULFATE
HIMBACINE A piperidine alkaloid that is decahydronaphtho[2,3-c]furan-1(3H)-one substituted by a methyl group at position 3 and a 2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl group at position 4. It has been isolated from the bark of Australian magnolias.
IPEROXO
IPRATROPIUM CATION
ISOPROPAMIDE IODIDE
K-252A A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a
KT 5720
KT 5823
LY593093
MCN-A-343
MEPENZOLATE BROMIDE
METHANTHELINE
METHIXENE
METHOCTRAMINE A tetramine that is N,N'-bis(6-aminohexyl)octane-1,8-diamine where the primary amino groups both carry 2-methoxybenzyl substituents.
METHSCOPOLAMINE
METHSCOPOLAMINE BROMIDE
METHYLFURMETHIDE
METHYLHOMATROPINE
METOCLOPRAMIDE HYDROCHLORIDE
MILAMELINE
MIPS1780
MK-7622
ML169
ML381
MUSCARINIC TOXIN 1
MUSCARINIC TOXIN 2
MUSCARINIC TOXIN 7
N-BENZYL BRUCINE
N-CHLOROMETHYL-BRUCINE
NEBRACETAM
NGX-267
NGX267
NNC 11-1314
NNC 11-1585
NNC 11-1607
OCTOTROPINE METHYLBROMIDE
OTENZEPAD
OXOTREMORINE A N-alkylpyrrolidine that has formula C12H18N2O.
OXOTREMORINE-M
OXYBUTYNIN An acetylenic compound that has formula C22H31NO3.
OXYPHENCYCLIMINE
OXYPHENCYCLIMINE HYDROCHLORIDE
OXYPHENONIUM
OXYPHENONIUM BROMIDE
P-F-HHSID
PENTYLTHIO-TZTP
PF-06767832
PIPERTRAMINE
PIPERTRAMINE AMIDE
PIRENZEPINE
PROCYCLIDINE
PROCYCLIDINE HYDROCHLORIDE
PROPANTHELINE
REVEFENACIN
SABCOMELINE
SCOPOLAMINE A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol.
SOFPIRONIUM BROMIDE
SOLIFENACIN
STRYCHNINE
T440
T532
TAK-071
TALSACLIDINE
THIETHYLPERAZINE
THIOCHROME
THIOPILOCARPINE
TOLTERODINE A tertiary amine that has formula C22H31NO.
TRIDIHEXETHYL
TRIDIHEXETHYL CHLORIDE
TRIFLUPROMAZINE
TRIHEXYPHENIDYL HYDROCHLORIDE
TRIPITRAMINE
TROSPIUM
T‐495
UMECLIDINIUM BROMIDE
VU0029767
VU0090157
VU0119498
VU0255035
VU0467319
VU0486846
WIN 51,708
XANOMELINE A tetrahydropyridine that has formula C14H23N3OS.
XANOMELINE TARTRATE
[11C]BUTYLTHIO-TZTP
[11C]XANOMELINE
[3H]ACETYLCHOLINE
[3H]IPEROXO
[3H]N-METHYL SCOPOLAMINE
[3H]PIRENZEPINE
[3H]QNB
AE9C90CB
BAY2413555
BETHANECHOL CHLORIDE
C7/3-PHTH
DARIFENACIN HYDROBROMIDE
DEXETIMIDE
DIMETHYL-W84
DOXACURIUM
DOXACURIUM CHLORIDE The dichloride salt of doxacurium. It is a mixture of the (1R,2S,1'S,2'R), (1R,2S,1'R,2'S) and (1S,2R,1'S,2'R) stereoisomers (a meso isomer and two enantiomers, respectively) of 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxypropane-3,1-diyl)]bis[6,7,8-trimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolinium] dichloride, all of which are in a trans configuration at the 1 and 2 positions of the tetrahydroisoquinolinium rings. A competitive neuromuscular blocker, it is used to provide muscle relaxation in general anaesthesia and to facilitate mechanical ventilation in patients in intensive care.
DUO3
ENDO-ATROPINE
FESOTERODINE FUMARATE
FLUTICASONE/SALMETEROL
GALLAMINE TRIETHIODIDE
HEXAHYDRODIFENIDOL
HEXOCYCLIUM
LEVETIMIDE
LITHOCHOLYLCHOLINE
LY2033298
LY2119620
MEPENZOLATE
METHACHOLINE CHLORIDE A quaternary ammonium salt that has formula C8H18NO2.Cl.
NAPHMETHONIUM
OXYBUTYNIN CHLORIDE
SCH 57790
SILAHEXOCYCLIUM
SOLIFENACIN SUCCINATE
THRX160209
TOLTERODINE TARTRATE
TROPICAMIDE
TROSPIUM CHLORIDE
UH-AH 37
W-84
WDUO3
ZAMIFENACIN
[3H]DIMETHYL-W84
[3H]OXOTREMORINE-M
[3H]TIOTROPIUM
ACETYLCHOLINE CHLORIDE
ACLIDINIUM BROMIDE
AZD-9164
AZD8683
CCG-50014
CHEMBL:CHEMBL1084941
CYCLOPENTOLATE HYDROCHLORIDE
IMIDAFENACIN
IPRATROPIUM BROMIDE The anhydrous form of the bromide salt of ipratropium. An anticholinergic drug, ipratropium bromide blocks the muscarinic cholinergic receptors in the smooth muscles of the bronchi in the lungs. This opens the bronchi, so providing relief in chronic obstructive pulmonary disease and acute asthma.
TARAFENACIN
TIOTROPIUM BROMIDE
[3H]4-DAMP
EMRACLIDINE
MK-6884
PCS1055
PD 102807
VU0010010
VU0467154
BELLADONNA EXTRACT, USP
BUTYLSCOPOLAMINE
CIMETROPIUM BROMIDE
CRYPTENAMINE ACETATES
EMEPRONIUM
FLUTROPIUM BROMIDE
GLYCERYLPHOSPHORYLCHOLINE
HYOSCYAMINE
ISPAGHULA HUSK
MEBEVERINE
ML375
ML380
OXITROPIUM BROMIDE
PRAMIRACETAM
PRIFINIUM
PROPIVERINE
VU0238429
VU6007678
&ALPHA;-BUNGAROTOXIN
&ALPHA;-CONOTOXIN GI
&ALPHA;-CONOTOXIN MI
ATRACURIUM A diester compound consisting of pentane-1,5-diol with both hydroxyls bearing 3-[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolinium-2(1H)-yl]propanoyl groups.
CISATRACURIUM BESYLATE The (1R,1'R,2R,2'R)-diastereoisomer of atracurium besylate. Commercial preparations of atracurium are mixtures of 10 stereoisomers, of which cisatracurium generally constitutes about 15%. Cisatracurium besylate is about 3 times more potent than the mixture of atracurium isomers as a neuromuscular blocking agent, and is used as a muscle relaxant for endotracheal intubation, to aid controlled ventilation, and in general anaesthesia.
DECAMETHONIUM BROMIDE
EFGARTIGIMOD ALFA
MECAMYLAMINE
METOCURINE IODIDE
MIVACURIUM CHLORIDE
NIPOCALIMAB
PANCURONIUM A steroid ester in which a 5alpha-androstane skeleton is C-3alpha- and C-17beta-disubstituted with acetoxy groups and 2beta- and 16beta-disubstituted with 1-methylpiperidinium-1-yl groups. It is a non-depolarizing curare-mimetic muscle relaxant.
PANCURONIUM BROMIDE
PIPECURONIUM BROMIDE
RAPACURONIUM BROMIDE
ROZANOLIXIZUMAB
SUCCINYLCHOLINE CHLORIDE
TUBOCURARINE CHLORIDE
VECURONIUM BROMIDE The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium substituents.
WAGLERIN-1
[125I]&ALPHA;-BUNGAROTOXIN
[3H]&ALPHA;-BUNGAROTOXIN
&ALPHA;-CONOTOXIN RGIA
ALPHA-CONOTOXIN VC 1.1
MUSCARINE A monosaccharide that has formula C9H20NO2.
NERAMEXANE MESYLATE
PENTOLINIUM
RGIA4
TRIMETHAPHAN
[3H]METHYLLYCACONITINE
CP-601927
CYTISINE An organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking.
GANTACURIUM
HEXAMETHONIUM A quaternary ammonium salt that has formula C12H30N2.
LEVALLORPHAN
LY2087101
METOCURINE
PIPECURONIUM
[125I]EPIBATIDINE
[3H]CYTISINE
&ALPHA;-CONOTOXIN AUIB
&ALPHA;-CONOTOXIN MII
&ALPHA;-CONOTOXIN PNIA
&ALPHA;-CONOTOXIN TXIA
&ALPHA;-CONOTOXIN-GIC
A-867744
CHEMBL:CHEMBL2332279
CHEMBL:CHEMBL448084
CHEMBL:CHEMBL466398
COCAINE A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
LARAZOTIDE ACETATE
MECAMYLAMINE HYDROCHLORIDE
NS1738
PENTOLINIUM TARTRATE The bitartrate salt of pentolinium.
PHANTASMIDINE
SIMPINICLINE
TRIMETHAPHAN CAMSYLATE
A-85380
ABT-560
ALTINICLINE
ATG002
AZD1446
BUTABARBITAL A barbiturate that has formula C10H16N2O3.
BUTALBITAL A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. Frequently combined with other medicines, such as aspirin, paracetamol and codeine, it is used for treatment of pain and headache.
BUTOBARBITAL
COTININE
DEXMECAMYLAMINE
DIANICLINE
GANTACURIUM CHLORIDE
HEXOBARBITAL
ISPRONICLINE
LOBELINE
METHARBITAL
NS9283
PENTOBARBITAL SODIUM
POZANICLINE
RIVANICLINE
RPI-MN
SECOBARBITAL
SOFINICLINE
SUVN-911
TALBUTAL
TC-2216
TC-2559
TC-2696
TEBANICLINE TOSYLATE
THIOPENTAL A barbiturate, the structure of which is that of 2-thiobarbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
VARENICLINE TARTRATE
&ALPHA;-CONOTOXIN MII [H9A, L15A]
&ALPHA;-CONOTOXIN PIA
[125I]&ALPHA;-CONOTOXIN MII
&ALPHA;-CONOTOXIN ARIB
&ALPHA;-CONOTOXIN IMI
4BP-TQS
A-582941
ABT-107
ABT-126
APN1125
AQW051
AVL-3288
AZD0328
BNC-210
BNC375
BRADANICLINE
ENCENICLINE
FACINICLINE HYDROCHLORIDE
GTS-21
JNJ-39393406
JNJ1930942
METHYLLYCACONITINE A diterpenoid that has formula C37H50N2O10.
ND0801
PHA-543613
PHA-709829
PNU-120596
PNU-282987
PSAB-OFP
SOCLENICANT
SSR180711
TC-6987
[3H]A-585539
[3H]AZ11637326
PHTX-11
2,6-DIDEHYDROPEPEROMIN B
AILANTHINONE
CHEMBL:CHEMBL564009
CHEMBL:CHEMBL8483
COMPOUND 47 [PMID: 28737909]
GLAUCARUBINONE
PEPEROMIN E
PHA-408
BORDETELLA PERTUSSIS PERTACTIN AUTOTRANSPORTER
C3TD879
CHLOROTOXIN
IODINE I 131 TM-601
MOXIDECTIN
TOZULERISTIDE
TALNIFLUMATE
FENOFIBRIC ACID A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate.
NMD670
S-(-)CPB
S-(-)CPP
COBIPROSTONE
CUSTIRSEN SODIUM
DIPHENYLAMINE-2-CARBOXYLIC ACID
GATX2
LUBIPROSTONE
BUFALIN A 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo.
DESACETYLBUFOTALIN
NS5818
3-PHENYL-CPP
ZOLBETUXIMAB
LITIFILIMAB
GLCC14C18
CDC2-LIKE KINASE INHIBITOR
CHEMBL:CHEMBL269881
COMPOUND 17 [PMID: 23642479]
ETHYL 3-[(E)-2-AMINO-1-CYANOETHENYL]-6,7-DICHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLATE
LEUCETTAMINE B
ML315
MW01
MW05
CIRTUVIVINT
COMPOUND 20 [PMID: 30998356]
LORECIVIVINT
ROGOCEKIB
SB220025 Am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively.
TAKINIB
CHEMBL:CHEMBL117217
PI-103
TOMIVOSERTIB
COMPOUND 16Z [PMID: 35609303]
DORDAVIPRONE
CUSTIRSEN
SOTEVTAMAB
COMPOUND 7F [PMID: 29191554]
FULACIMSTAT
JNJ-10311795
NK3201
TY-51469
&ALPHA;-NETA
CHEMERIN
CHEMERIN C-TERMINAL PEPTIDE
COMPOUND 14F [PMID: 35063894]
LC52-0332
RESOLVIN E1 A leukotriene that has formula C20H30O5.
S-26D [PMID: 37883692]
TETHERED CHEMERIN 9
[3H]RESOLVIN E1
OSTN (81-102)
CYCLIC GMP
DEQUALINIUM
L-(CIS)-DILTIAZEM
CYCLIC AMP
2-ARACHIDONYL GLYCERYL ETHER
AB-5'F-BUTINACA
ADB-5'F-BUTINACA
ADB-BUTINACA
AM11542
AM2201
AM6538
AM6545
AM841
AMAUROMINE
AZD1940
AZD2207
BAY-593074
BMS-202
CB-13
CHEMBL:CHEMBL498746
COMPOUND 70 [PMID: 26161824]
DRINABANT
GAT100
GAT211
HEMOPRESSIN
HU-210
IBIPINABANT
JD5037
JWH-018
LENABASUM
LIRAGLUTIDE
LY320135
MDMB-FUBINACA
MONLUNABANT
MRI-1867
N-[6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDINE-4-YL]-4,4,4-TRIFLUORO-3-HYDROXYBUTANAMIDE (DIASTEREOMERIC MIX)
NABILONE
NESS0327
NIMACIMAB
NONABINE
OLORINAB
ORG27569
OTENABANT
PEPCAN-12
PF-514273
SAD448
SCH.336
SURINABANT
TEBIPENEM
TM38837
TM39875
V24343
VCE-004.3
VIP36
[3H]WIN55212-2
(E)-BETA-CARYOPHYLLENE
AM10257
AM1241
AM251
AM7499
CANNABINOR
COMPOUND C2 [PMID: 29990428]
FERRUGINENE C
GW405833
GW842166
JWH-133
JWH015
L-759,633
L-759,656
LY2828360
ONTERNABEZ
PHENYLACETYLRINVANIL
S-777469
SR144528
TEDALINAB
VICASINABIN
[3H]HU-243
CILIARY NEUROTROPHIC FACTOR
TP3 IMMUNOTOXIN
OCRIPLASMIN
GLUTAMINE
PAMIDRONATE
RECOMBINANT TRANSFORMING GROWTH FACTOR-BETA-2
NAVOXIMOD
TRC-093
BEREMAGENE GEPERPAVEC
CIGB-552
ALFENTANIL A member of the class of piperidines that is piperidine having a 2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl group at the 1-position as well as N-phenylpropanamido- and methoxymethyl groups at the 4-position.
ANHYDROUS DEXTROSE
ENTACAPONE
HYDROCODONE POLISTIREX
NEBICAPONE
OPICAPONE
TOLCAPONE
PROCAINAMIDE 4-Aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
QUININE A cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy.
TOCAINIDE
ACECLOFENAC
ACETYLSALICYLIC ACID/DIPYRIDAMOLE
AMTOLMETIN GUACIL
DEXIBUPROFEN
EICOSAPENTAENOIC ACID
FELBINAC
FENOPROFEN Propanoic acid in which one of the hydrogens at position 2 is substituted by a 3-phenoxyphenyl group. A non-steroidal anti-inflammatory drug, the dihydrate form of the calcium salt is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
FOSFOSAL
KETOROLAC TROMETHAMINE
LORNOXICAM
MORNIFLUMATE
NAPROXCINOD
NCX 1022
NCX-4016
NEPAFENAC
OXAPROZIN
PELUBIPROFEN
ME-344
NV-128
CARDIOPROTECTIVE AGENT
CLOMIPHENE CITRATE
DEXRAZOXANE
INTERFERON-BETA
PENICILLAMINE
PROTOPORPHYRIN IX
COMPOUND 1B [PMID: 18078750]
COMPOUND 3 [PMID: 14640538]
COMPOUND 4 [PMID: 19954973]
SQ-24,798
TAFIA INHIBITOR DS-1040B
UK-396,082
GIVOSIRAN
CARGLUMIC ACID
ACOZIBOROLE
LEVOCARNITINE PROPIONATE
PERHEXILINE
CDX-1135
MIROCOCEPT
AK-2292
AVADOMIDE
CBPD-268
DTAG-13
GOLCADOMIDE
IBERDOMIDE
LENALIDOMIDE
LENALIDOMIDE HYDROCHLORIDE MONOHYDRATE
MD-222
MEZIGDOMIDE
MG-277
MS40
NVP-DKY709
POMALIDOMIDE An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.
SB-405483
SJ995973
TL12-186
TX-16
(-)-ROLIPRAM
CBPD-409
CHEMBL:CHEMBL1797707
CHEMBL:CHEMBL1797708
CHEMBL:CHEMBL1797711
CHEMBL:CHEMBL1797712
CHEMBL:CHEMBL1797713
CHEMBL:CHEMBL257748
ETAZOLATE HYDROCHLORIDE
GNE-049
I-CBP112
INOBRODIB
ISCHEMIN
METHYLPHENIDATE HYDROCHLORIDE
MTOR INHIBITOR
PRI-724
SGC-CBP30
TRACAZOLATE
TTK21
IRX-2
&ALPHA;-HELICAL CRF
ANTALARMIN
ASTRESSIN A 30-membered homodetic cyclic peptide comprising the sequence D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Glu-Ala-His-Lys-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2 cyclised by an amide bridge, formed by condensation of the side-chain carboxy group of the Glu residue at position 19 and the side-chain amino group of the Lys residue at posoition 22.
ASTRESSIN 2B
CORTICOTROPHIN-RELEASING HORMONE
CORTICOTROPIN-RELEASING FACTOR
CP-316,311
CRA1000
CRINECERFONT
DMP696
EMICERFONT
NBI-34041
NBI27914
ONO-2333MS
PEXACERFONT
R121919
SAUVAGINE
TELAVANCIN
TILDACERFONT
UROCORTIN 1
UROCORTIN 2
UROTENSIN 1 (FISH)
VERUCERFONT
[125I]ASTRESSIN
[125I]CRF (OVINE)
[125I]SAUVAGINE (FROG)
[125I]TYR0-CRF (HUMAN, RAT, MOUSE)
[125I]UROCORTIN 1 (MOUSE, RAT)
ANTISAUVAGINE
K31440
K41498
UROCORTIN 3
[125I]ANTISAUVAGINE
BIIB-015
2-TERT-BUTYL-9-FLUORO-1,6-DIHYDROBENZO[H]IMIDAZO[4,5-F]ISOQUINOLIN-7-ONE
NCX-1000
VOXTALISIB
KL044
DOXAPRAM A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
CSF1R INHIBITOR PLX73086
EMACTUZUMAB
MCS-110
PD-360324
AC710
AMG-820
AMG820
ANTI-C-FMS MONOCLONAL ANTIBODY AMG 820
ARRY-382
AXATILIMAB
AZD6495
BLZ-945
BPR1R024
CABIRALIZUMAB
CERDULATINIB
CHMFL-KIT-64
COMPOUND 29 [PMID: 31934767]
CT-1578
EDICOTINIB
ELZOVANTINIB
ENRUPATINIB
GR-389988
GTP-14564
GW-2580
IACS-9439
IL-34
IMC-CS4
JNJ-28312141
KI-20227
LY3022855
M-CSF
ONATASERTIB
OSI-930
PAZOPANIB HYDROCHLORIDE
PEXIDARTINIB HYDROCHLORIDE
PIMICOTINIB
PLX-7486
PLX5622
PLX7486
SEGIGRATINIB
SERALUTINIB
SOTULETINIB
SULFATINIB
SUNITINIB MALATE
VELZATINIB
VIMSELTINIB
BCG VACCINE
CRETOSTIMOGENE GRENADENOREPVEC
FAMCICLOVIR 2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
GEMOGENOVATUCEL-T
GIMSILUMAB
GM-CSF-ENCODING ONCOLYTIC ADENOVIRUS CGTG-102
GP100 ANTIGEN
HORSE ANTI-MOUSE ANTI-LYMPHOCYTE SERUM
KB002
LACTULOSE A synthetic galactosylfructose disaccharide used in the treatment of constipation and hepatic encephalopathy.
LENZILUMAB
MAVRILIMUMAB
MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1
MELANOMA VACCINE
NAMILUMAB
OTILIMAB
PERFOSFAMIDE
PEXASTIMOGENE DEVACIREPVEC
PLONMARLIMAB
ROQUINIMEX
STAVUDINE A nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase
TALIMOGENE LAHERPAREPVEC
TICARCILLIN
TRIVALENT INFLUENZA VACCINE
VACCINE
MILODISTIM
MOLGRAMOSTIM
SARGRAMOSTIM
CIBINETIDE
TAGRAXOFUSP
TALACOTUZUMAB
EFBEMALENOGRASTIM ALFA
EFLAPEGRASTIM
INTERLEUKIN-3
PEGFILGRASTIM BIOSIMILAR LA-EP2006
RECOMBINANT HUMAN ALBUMIN-HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR
TALABOSTAT
ANUMIGILIMAB
AZD1480
BALUGRASTIM
GLYCOPEG-GCSF
LIPEGFILGRASTIM
MAXY-G34
PEGFILGRASTIM
PEGTEOGRASTIM
REGRAMOSTIM
TBO-FILGRASTIM
TOFACITINIB
AMCASERTIB
NG-25
PP1
RIVOCERANIB
ABT-002
COMPOUND 14 [PMID: 24900428]
D4476
RELZASERTIDEG
RICININE
SB-242235
SB203580
4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE
JNJ-6204
PF-4800567
PF-670462
R-1487
SR-4133
UMBRALISIB
SGC-CK1&GAMMA;-1
COMPOUND 14K [PMID: 21982499]
COMPOUND 1A [PMID: 24900749]
COMPOUND 2C [PMID: 22115617]
KDX1381
SILMITASERTIB
RASDEGAFUSP ALFA
ANTI-NY-ESO-1 IMMUNOTHERAPEUTIC GSK-2241658A
LETETRESGENE AUTOLEUCEL
CEFUROXIME SODIUM
CEPHALOTHIN
CHEMBL:CHEMBL1443422
CHEMBL:CHEMBL477936
CHEMBL:CHEMBL581449
LITHOCHOLIC ACID A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
NALOXONE METHIODIDE
CARDIOTROPHIN-1
&BETA;-CYANO-L-ALANINE
AMINOETHOXYVINYLGLYCINE
PROPARGYLGLYCINE
CADONILIMAB
FF-10501-01
INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE INHIBITOR FF-10501-01
LORIGERLIMAB
NURULIMAB
QUAVONLIMAB
RETRO-INVERSO PEPTIDE
TUVONRALIMAB
ZALIFRELIMAB
ANTI-CTLA-4 MONOCLONAL ANTIBODY
BAY1217389
CEQ508
CHEMBL:CHEMBL2172378
EMPESERTIB
EOSIN_Y
FLUORESCEIN SODIUM
MPI-0479605
MPS1-IN-1
NMS-P715
RECOMBINANT HUMAN ENDOSTATIN
SAM68 MODULATOR CWP232291
ACETYLDIGOXIN
COMPOUND 27 [PMID: 36449304]
CYCLOPENTENYL CYTOSINE
BETA PH61
COMPOUND 20 [PMID: 12372533]
MILVEXIAN
COMPOUND 8A [PMID: 22861813]
EXAMPLE 166 [WO2014154727]
COMPOUND 1 [PMID: 40415551]
K11777
LHVS
POSTSTATIN
VBY-825
Z-ARG-LEU-VAL-AGLY-ILE-VAL-OME
BRENSOCATIB
COMPOUND 3D [PMID: 3941405]
GSK2793660
HSK31858
ICATCXPZ-01
PENTOSAN POLYSULFATE
COMPOUND 1 [PMID: 10498202]
COMPOUND 3 [PMID: 8410973]
COMPOUND 33 [PMID: 32003991]
GRASSYSTATIN G
COMPOUND 2 [PMID: 8410973]
COMPOUND (R)-26 [PMID: 22686657]
COMPOUND 1 [PMID: 11425539]
COMPOUND 4G [PMID: 22595175]
LYMPHOKINE-ACTIVATED KILLER CELLS
MANNITOL A hexitol produced by a variety of organisms including bacteria, fungi, lichens and plants.
SULFONE ANTI-INFECTIVE AGENT
VITAMIN K A fat-soluble vitamin required for the synthesis of prothrombin and certain other blood coagulation factors.
COMPOUND 1B [PMID: 16290936]
COMPOUND 1E [PMID: 27285276]
BALICATIB
CHEMBL:CHEMBL2316602
COMPOUND 23 [PMID: 35944849]
L873724
MIV-701
ODANACATIB
ONO-5334
RELACATIB
AC1115
ACETYLLEUCYL-LEUCYL-NORLEUCINAL A tripeptide composed of N-acetylleucyl, leucyl and norleucinyl residues joined in sequence.
COMPOUND 4D [PMID: 38746883]
D6-3
GALLINAMIDE A
KGP94
MPRO INHIBITOR 13B
LY3000328
PETESICATIB
CITIBRASINE
CITRUSININE II
QUETMOLIMAB
AZD0233
CX3CL1 chemokine (C-X3-C motif) ligand 1|
JMS-17-2
RUGOCRIXAN
[125I]CX3CL1 (HUMAN)
ELDELUMAB
IROPLACT
NI-0801
OLAPTESED PEGOL
BATIMASTAT
BETA-GLUCAN
RECOMBINANT NEUROTROPHIC FACTOR
13-CIS-RETINAL A retinal in which the double bond alpha- to the aldehyde group has cis configuration, whilst the remaining acyclic double bonds have trans configuration.
ABX-IL8
ADAKITUG
ALDRIN An organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with norbornadiene. It was widely used as an insecticide before being banned in the 1970s as a persistent organic pollutant.
ALUMINUM HYDROXIDE
BIOFLAVONOID
CEFTRIAXONE SODIUM
CIDOFOVIR ANHYDROUS
CORONOPILIN
FOSCARNET SODIUM
KLEBSIELLA PNEUMONIAE GLYCOPROTEIN
PROTECTIVE AGENT
RECOMBINANT INTERFERON ALFA
TALC
VITAMIN E ACETATE
AZD5069
CANOCTAKIN
CXCL6 chemokine (C-X-C motif) ligand 6|
CXCL8 chemokine (C-X-C motif) ligand 8|The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
CYTOKINE DOMAIN OF TYROSYL TRNA SYNTHETASE
LADARIXIN
MINI-TYRRS
NAVARIXIN
REPARIXIN
SX-682
VCXCL1
[125I]CXCL8 (HUMAN)
[125I]MINI-TYRRS
AZD-5122
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)|This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
CXCL2 chemokine (C-X-C motif) ligand 2|This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
CXCL3 chemokine (C-X-C motif) ligand 3|This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]
CXCL5 chemokine (C-X-C motif) ligand 5|This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
CXCL7
DANIRIXIN
ELUBRIXIN
HIV-1 MATRIX PROTEIN P17
NSC 157449
SB 225002
SX-517
VIMNERIXIN
[125I]CXCL1 (HUMAN)
[125I]CXCL5 (HUMAN)
[125I]CXCL7 (HUMAN)
ACT-660602
ACT-777991
AMG487
DIOSCIN A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage.
DURAMYCIN
HYPOGLAUCIN A
KALLSTROEMIN D
NBI-74330
[125I]CXCL10 (HUMAN)
[125I]CXCL11 (HUMAN)
BALIXAFORTIDE
BURIXAFOR
CHEMBL:CHEMBL1221944
CHEMBL:CHEMBL1242210
CHEMBL:CHEMBL2062277
CHEMBL:CHEMBL2347630
CHEMBL:CHEMBL2347631
CHEMBL:CHEMBL2347632
CHEMBL:CHEMBL2347633
COMPOUND 46C [PMID: 29350534]
COMPOUND XVI [PMID: 38863440]
CTCE-0214
CTCE-9908
CX549
CXCL12&BETA;
CXCL12&DELTA;
CXCL12&EPSILON;
CXCL12&GAMMA;
CXCL12&PHI;
CXCL12-(1-17)
CXCL12-(1-9)
CXCL12-(1-9) DIMER
CXCL122 (DIMER)
CXCL12H25R (MONOMER)
CXCR4 ANTAGONIST 22
CXCR4 ANTAGONIST USL311
GMI-1359
ISOTHIOUREA-1A
ISOTHIOUREA-1T
LY-2624587
MAVORIXAFOR
MOTIXAFORTIDE
MSX-122
PF-06747143
SDF-1, 1-9[P2G] DIMER
SDF1 P2G
T134
T140
T22
TIQ-15
ULOCUPLUMAB
X4-HIV-1 GP120
[125I]CXCL12&ALPHA; (HUMAN)
[125I]CXCL12&BETA; (HUMAN)
CXCL13 chemokine (C-X-C motif) ligand 13|B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer&apos;s patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt&apos;s lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Oct 2014]
CXCL16 chemokine (C-X-C motif) ligand 16|
[125I]CXCL16 (HUMAN)
ISOSORBIDE DINITRATE A glucitol derivative that has formula C6H8N2O8.
ISOSORBIDE MONONITRATE A glucitol derivative that has formula C6H9NO6.
PRIMAQUINE A N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
RASBURICASE
ARTICAINE / EPINEPHRINE
BUPIVACAINE A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
DAPSONE A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.
DRUGSATFDA.NDA:021717
ROPIVACAINE The piperidinecarboxamide obtained by the formal condensation of N-propylpipecolic acid and 2,6-dimethylaniline.
COMPOUND 7C [PMID: 22041175]
GKT136901
NSC 780521
SETANAXIB
(2S,4S)-KETOCONAZOLE
AMINOGLUTETHIMIDE
OPEVESOSTAT
DEXFADROSTAT
FADROZOLE
LORUNDROSTAT
METYRAPONE
OSILODROSTAT
OSILODROSTAT PHOSPHATE
VICADROSTAT
BAXDROSTAT
HYDRALAZINE / ISOSORBIDE DINITRATE
ABIRATERONE-C6 OXIME
LAPITERONEL
ORTERONEL
YXG-158
ALENDRONATE SODIUM
ANABOLIC STEROID
ATAMESTANE
AZALANSTAT
AZTREONAM
CHEMBL:CHEMBL1077603
CHEMBL:CHEMBL572637
ENDOXIFEN
FADROZOLE HYDROCHLORIDE
GONADOTROPIN-RELEASING HORMONE ANALOG
ISOPROPYL ALCOHOL
LIAROZOLE
MPI-674
NARINGENIN A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'.
NORENDOXIFEN
5H3'FPE
65PF
AMODIAQUINE
DIOSMETIN A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin.
GRANISETRON
PHYTOCHEMICAL
(R,S)-IFENPRODIL
(S)-ALAPROCLATE
(S)-MEXILETINE
(S)-MIDODRINE
(S)-NIMODIPINE
(S)-ONDANSETRON
(S)-PINACIDIL
(Z)-PIPLARTINE
1-PHENYLBIGUANIDE
17-OCTADECYNOIC ACID
2(R)-MECAMYLAMINE
2,3-DIHYDROXY-6,7-DICHLOROQUINOXALINE
3,4-DICHLOROBENZAMIL
3-ACETYLCOUMARIN
3-HYDROXYBENZYLHYDRAZINE
4',7-DIMETHOXY-5-HYDROXYGENISTEIN
5-(N-METHYL-N-ISOBUTYL)AMILORIDE
5-CT
5-HYDROXYTRYPTAMINE
5-MEO-DMT
5-MEOT
5H78PF
6-BENZYLAMINOPURINE
6-CL-MLT
6-NITROQUIPAZINE
6-O-BENZYLGUANINE
8-PHENYL THEOPHYLLINE
ACEPROMAZINE A member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10.
ADIPHENINE
ALTRETAMINE
ALVERINE CITRATE
AMIDATE
AMOXICILLIN ANHYDROUS
ANHYDROUS LACTOSE
ANIRACETAM
ANTIPSYCHOTIC AGENT Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
ARASERTACONAZOLE
BENOXINATE
BENZOCAINE A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.
BENZYDAMINE
BERBERINE
BETA-CCM
BIFEMELANE
BMS-191011
BOLDINE An isoquinoline alkaloid that has formula C19H21NO4.
BRILLIANT GREEN OXALATE
BROMAZEPAM
BUDESONIDE A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.
BUFEXAMAC
BUTORPHANOL Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.
BUTYLATED HYDROXYTOLUENE
BUTYLPARABEN
CARBIMAZOLE
CGP 54626A
CGP7930
CGS-12066
CHEMBL:CHEMBL101168
CHEMBL:CHEMBL11458
CHEMBL:CHEMBL1162521
CHEMBL:CHEMBL1179
CHEMBL:CHEMBL123904
CHEMBL:CHEMBL1269022
CHEMBL:CHEMBL1288013
CHEMBL:CHEMBL1288106
CHEMBL:CHEMBL1317986
CHEMBL:CHEMBL1320453
CHEMBL:CHEMBL1337960
CHEMBL:CHEMBL1342336
CHEMBL:CHEMBL1367935
CHEMBL:CHEMBL1371696
CHEMBL:CHEMBL140220
CHEMBL:CHEMBL1420370
CHEMBL:CHEMBL1477383
CHEMBL:CHEMBL1479195
CHEMBL:CHEMBL1491455
CHEMBL:CHEMBL1520837
CHEMBL:CHEMBL1569213
CHEMBL:CHEMBL177809
CHEMBL:CHEMBL187216
CHEMBL:CHEMBL189724
CHEMBL:CHEMBL2094549
CHEMBL:CHEMBL216973
CHEMBL:CHEMBL221300
CHEMBL:CHEMBL227298
CHEMBL:CHEMBL228132
CHEMBL:CHEMBL250428
CHEMBL:CHEMBL258465
CHEMBL:CHEMBL259103
CHEMBL:CHEMBL271165
CHEMBL:CHEMBL287689
CHEMBL:CHEMBL29197
CHEMBL:CHEMBL294747
CHEMBL:CHEMBL296407
CHEMBL:CHEMBL3039597
CHEMBL:CHEMBL338404
CHEMBL:CHEMBL362223
CHEMBL:CHEMBL362863
CHEMBL:CHEMBL363332
CHEMBL:CHEMBL404505
CHEMBL:CHEMBL43528
CHEMBL:CHEMBL45245
CHEMBL:CHEMBL458765
CHEMBL:CHEMBL471225
CHEMBL:CHEMBL471226
CHEMBL:CHEMBL472656
CHEMBL:CHEMBL476501
CHEMBL:CHEMBL512908
CHEMBL:CHEMBL527271
CHEMBL:CHEMBL530733
CHEMBL:CHEMBL533542
CHEMBL:CHEMBL582507
CHEMBL:CHEMBL584860
CHEMBL:CHEMBL587259
CHEMBL:CHEMBL588859
CHEMBL:CHEMBL591613
CHEMBL:CHEMBL592561
CHEMBL:CHEMBL601110
CHEMBL:CHEMBL601135
CHEMBL:CHEMBL602418
CHEMBL:CHEMBL609628
CHEMBL:CHEMBL74189
CHEMBL:CHEMBL85194
CHLORZOXAZONE A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
CI-218872
CIMETIDINE A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
CIS-RESVERATROL
CLEMASTINE 2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions.
CLEMIZOLE
CLOBENPROPIT An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
CLOMETHIAZOLE
CLONAZEPAM 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
CLORGILINE
CORYNANTHINE
CROMOGLYCATE
DANTROLENE The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin.
DEXPROPRANOLOL
DIBUCAINE
DIHYDREXIDINE
DIHYDROCAPSAICIN A capsaicinoid that has formula C18H29NO3.
DIMETHISOQUIN
DIOXYBENZONE
DIPHENHYDRAMINE An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
DUP-697
ECADOTRIL
ECHINACEA EXTRACT
EPIRIZOLE
ESOXYBUTYNIN
ETICLOPRIDE
ETIOCHOLANOLONE
ETOFENAMATE
FELBAMATE
FENBENDAZOLE
FERROUS SULFATE
FIPEXIDE
FURAFYLLINE
GF109203X
GLAFENINE
GLYCINE The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain.
GR 113808 An indolyl carboxylate ester obtained by formal condensation between the carboxy group of 1-methylindole-3-carboxylic acid with the hydroxy group of N-{2-[4-(hydroxymethyl)piperidin-1-yl]ethyl}methanesulfonamide.
GRAVEOLINE
GS39783
GUAIFENESIN
GW282974X
HESPERETIN A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position.
HYDRAZINE An azane that has formula H4N2.
HYDROCOTARNINE
HYDROXYZINE A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
IBUDILAST
IMAZODAN
IODOPHENPROPIT
IPRATROPIUM A propanoate ester that has formula C20H30NO3.
IPRONIAZID
ISOCARBOXAZID
ISOXSUPRINE
KHELLIN
L-694,247
L-741,626
LANSOPRAZOLE SULFIDE
LEUCINE
LINEZOLID
LORECLEZOLE
LUZINDOLE
M-CHLOROPHENYLPIPERAZINE
MEBENDAZOLE A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
MECLIZINE
MECLOFENOXATE
MEFENAMIC ACID An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
MELATONIN A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans.
MENTHOFURAN
MEPIVACAINE HYDROCHLORIDE
METHOXSALEN
METIZOLINE
MINOCYCLINE A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5.
MK-212
MONOBENZONE
N-OLEOYLETHANOLAMIDE
N-[2-(2-IODO-5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE
NABUMETONE
NALBUPHINE HYDROCHLORIDE
NB-ACETYLTRYPTAMINE
NEOSTIGMINE BROMIDE
NIACIN
NIRIDAZOLE
NS 2028
NS1619
O6-BENZYLGUANINE
OLEAMIDE A fatty amide derived from oleic acid.
PD168,077
PF-03715455
PHENACETIN
PIPERACETAZINE
PIRFENIDONE
POLYPHYLLIN H
PRAZIQUANTEL A pyrazinoisoquinoline that has formula C19H24N2O2.
PROPARACAINE
PROPENTOFYLLINE
PROPOXYCAINE
PROPYLENE GLYCOL
PSORA-4
PURVALANOLA
PYRILAMINE
QUAZINONE
QUIPAZINE
REL-CISAPRIDE
REMOXIPRIDE
RILUZOLE
RIMCAZOLE
RU 24969
S(+)-APOMORPHINE
S-ETOMIDATE
SB 203186
SB 204070
SB 215505
SB 218795
SB 228357 An indolyl carboxylic acid that has formula C22H17F4N3O2.
SB-334867
SB-408124
SC-560 A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 5 by 4-methoxyphenyl, trifluoromethyl and 4-chlorophenyl groups, respectively. Unlike many members of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors, SC-560 is selective for COX-1.
SDZ 205557
SPERMIDINE A triamine that is the 1,5,10-triaza derivative of decane.
SPICLOMAZINE
SPLITOMICIN A benzochromenone that is 2,3-dihydro-1H-benzo[f]chromene substituted by an oxo group at position 3. It has been found to exhibit potential inhibitory activity against Sir2 proteins.
SULFADOXINE
SULFAPHENAZOLE A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
SULMAZOLE
TETRACYCLINE A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.
THIOPERAMIDE A primary aliphatic amine that has formula C15H24N4S.
TICLOPIDINE A thienopyridine that has formula C14H14ClNS.
TICRYNAFEN
TODRALAZINE
TOLNAFTATE
TRAPIDIL
TRIM
TRIMETAZIDINE
TRIOXSALEN
TROLEANDOMYCIN
TRYPTAMINE An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.
ZARDAVERINE A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.
ZOXAZOLAMINE A benzoxazole that has formula C7H5ClN2O.
ZUCLOPENTHIXOL
2'H,4H-[2,5'-BICHROMEN]-4-ONE
2'H,4H-[2,8'-BICHROMEN]-4-ONE
2,3',4,5'-TETRAMETHOXYSTILBENE
ALPHA-NAPHTHOFLAVONE An extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14).
CHEMBL:CHEMBL2347759
PINOCEMBRIN A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.
ZYC300
CARBENDAZIM A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables.
COMPOUND 4D [PMID: 20655626]
CTA091
DACLATASVIR
LUNACALCIPOL
TENOFOVIR DISOPROXIL FUMARATE
COMPOUND 5 [PMID: 21838328]
R116010
TALAROZOLE
CHEMBL:CHEMBL2036072
3-FORMYLINDOLE
CHEMBL:CHEMBL1770735
COMPOUND 23 [PMID: 17125252]
COMPOUND 38A [PMID: 15634016]
COMPOUND 39A [PMID: 15634016]
ESCULETIN Umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.
3,4-METHYLENEDIOXYMETHAMPHETAMINE A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
ARTEMOTIL
EMTRICITABINE/TENOFOVIR/EFAVIRENZ
ESMETHADONE
LEVAMISOLE HYDROCHLORIDE
OSPEMIFENE An organochlorine compound that is a selective estrogen receptor modulator; used for treatment of dyspareunia.
SIBUTRAMINE
TROFOSFAMIDE
COMPOUND 9 [PMID: 11606127]
(-)-U-50488
(R)-FELODIPINE
(R)-FLECAINIDE
(R)-NFPS
(R)-NITRENDIPINE
(R)-PINOCEMBRIN
(S)-AMPA
(S)-FELODIPINE
(S)-NITRENDIPINE
1R,9S-HYDRASTINE
6BETA-HYDROXYTESTOSTERONE A 17beta-hydroxy steroid that is testosterone bearing an additional hydroxy substituent at the 6beta-position.
A68930
ABROCITINIB
AM281
AMBRISENTAN
AMITRIPTYLINOXIDE
ANABASINE A pyridine alkaloid that is pyridine substituted by a piperidin-2-yl group at position 3.
AROTINOID ACID
ASARININ
BELZUTIFAN
BRIVARACETAM
CAPENSIN
CHEMBL:CHEMBL1256869
CHEMBL:CHEMBL1257081
CHEMBL:CHEMBL1270168
CHEMBL:CHEMBL1288014
CHEMBL:CHEMBL1310701
CHEMBL:CHEMBL1339015
CHEMBL:CHEMBL1358137
CHEMBL:CHEMBL1370698
CHEMBL:CHEMBL145725
CHEMBL:CHEMBL1513392
CHEMBL:CHEMBL1548739
CHEMBL:CHEMBL16751
CHEMBL:CHEMBL188641
CHEMBL:CHEMBL242172
CHEMBL:CHEMBL242385
CHEMBL:CHEMBL250053
CHEMBL:CHEMBL272005
CHEMBL:CHEMBL277863
CHEMBL:CHEMBL335741
CHEMBL:CHEMBL512832
CHEMBL:CHEMBL547407
CHEMBL:CHEMBL552439
CHEMBL:CHEMBL584854
CHEMBL:CHEMBL585045
CHEMBL:CHEMBL71294
CHLOROPYRAMINE
CLOBAZAM
COMPOUND 30 [PMID: 22239545]
COMPOUND 51 [CROSIGNANI ET AL., 2011]
CP-339818
DEGUELIN An isoflavanone that has formula C23H22O6.
DIFLUFENICAN
DIPYRONE
DL-TBOA
E4031
FLIBANSERIN
FLUMAZENIL A 1,4-benzodiazepine that has formula C15H14FN3O3.
FLUNITRAZEPAM
GLABRANIN
GW1929
GYKI53784
HYDRASTINE
ICI-199441
ICILIN
ICOTINIB
IPSAPIRONE
KARANJIN
L-732,138
L-733,060
LINOPIRDINE An indole that has formula C26H21N3O.
MANGOSTIN
MAVACAMTEN
MONO-N-ACETYL DAPSONE
NORMEPERIDINE
NOSCAPINE
OXYCODONE An organic heteropentacyclic compound that has formula C18H21NO4.
PHENPROCOUMON
PROGUANIL
PSORALEN
RACLOPRIDE
RESOKAEMPFEROL
RS67506
SALAGEN
SELEGILINE
TECHTOCHRYSIN
TELENZEPINE
TEMAZEPAM
UBP302
UE2343
VONOPRAZAN
ZD-7155
[3H]GABAZINE
CERIVASTATIN (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.
DESETHYLCHLOROQUINE
MACITENTAN A member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension.
SELEXIPAG
VOXELOTOR
(-)-USNIC ACID
3,6-DIMETHOXYFLAVONE
3-AMINOBENZAMIDE A substituted aniline that is benzamide in which one of the meta- hydrogens is replaced by an amino group.
AFICAMTEN
APATINIB
ARCTIGENIN
BMS-182874
BW373U86
CHEMBL:CHEMBL1374610
CHEMBL:CHEMBL1611308
CHEMBL:CHEMBL222808
CHEMBL:CHEMBL225513
CHEMBL:CHEMBL253786
CHEMBL:CHEMBL311489
CHEMBL:CHEMBL876
CI-966
COMPOUND 3 [PMID: 18255300]
DEURUXOLITINIB
DEXTROTHYROXINE
ERDAFITINIB
ETHAVERINE
ETRASIMOD
FAMPROFAZONE
FOSPHENYTOIN
INDOMETHACIN MORPHOLINYLAMIDE
LESINURAD
LUMIRACOXIB An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity.
PIMARIC ACID
PIOGLITAZONE HYDROCHLORIDE
RO 04-6790
ROSIGLITAZONE
SELADELPAR
SIPONIMOD
TIRATRICOL
VANIPREVIR
{4-[3-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY)PROPOXY]PHENOXY}ACETIC ACID
(R)-PROCYCLIDINE
(S)-UH 301
7-HYDROXYCHLORPROMAZINE
ACETAMINOPHEN / CAFFEINE / DIHYDROCODEINE
ACETAMINOPHEN / CODEINE
AGROCLAVINE
AMOXAPINE A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
AMPHETAMINE SULFATE
ANTAZOLINE
ATOMOXETINE HYDROCHLORIDE
BENPERIDOL
BENZETHONIUM
BP 897
BREXPIPRAZOLE
BROMPERIDOL
BUCLADESINE A 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP.
BUFLOMEDIL
BUTACAINE
CARBETAPENTANE
CARBETAPENTANE CITRATE
CARIPRAZINE
CGP13501
CGP55845
CHEMBL:CHEMBL101510
CHEMBL:CHEMBL1096339
CHEMBL:CHEMBL1314044
CHEMBL:CHEMBL1329326
CHEMBL:CHEMBL1371493
CHEMBL:CHEMBL1393947
CHEMBL:CHEMBL1394328
CHEMBL:CHEMBL1410004
CHEMBL:CHEMBL1593717
CHEMBL:CHEMBL20377
CHEMBL:CHEMBL279556
CHEMBL:CHEMBL287327
CHEMBL:CHEMBL303336
CHEMBL:CHEMBL389390
CHEMBL:CHEMBL51697
CHEMBL:CHEMBL541543
CHEMBL:CHEMBL547101
CHEMBL:CHEMBL66114
CLEBOPRIDE
CLOFIBRIC ACID A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.
DESVENLAFAXINE SUCCINATE
DEUTETRABENAZINE
DEXTROMEPROMAZINE
DEXTROMETHORPHAN POLISTIREX
DEXTROMETHORPHAN/QUINIDINE
DIHYDROMORPHINE A morphinane alkaloid that has formula C17H21NO3.
DIHYDROSPHINGOSINE
DIMENHYDRINATE The diphenhydramine salt of 8-chlorotheophylline. Its effects are similar to those of diphenhydramine, but it is less potent. It was thought that by combining the antiemetic effects of diphenhydramine with the mild stimulant effects of 8-chlorotheophyline, the extreme drowsiness induced by the former would be mitigated. However, the sedation caused by diphenhydramine is considerably stronger than the stimulation caused by 8-chlorotheophylline. Dimenhydrinate is used mainly as an antiemetic in the prevention and treatment of motion sickness.
DIMETACRINE
DIPHENYLPYRALINE
DISOPYRAMIDE A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
DROPERIDOL An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.
ELETRIPTAN
ELIGLUSTAT A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.
ETHYLISOTHIOUREA
ETHYLMORPHINE
FLUOXETINE / OLANZAPINE
GLUTETHIMIDE
GR-55562
GRAMINE
HALOFANTRINE HYDROCHLORIDE
HARMOL
HYDROMORPHONE HYDROCHLORIDE
IBOGAINE A monoterpenoid indole alkaloid that has formula C20H26N2O.
IMETIT An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.
IOBENGUANE
ISOPROPAMIDE
ISOQUINE
KETANSERIN TARTRATE
KETOPROFEN An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
KETOTIFEN FUMARATE
L701324
LEVOPROPOXYPHENE NAPSYLATE
LIDOFLAZINE
MEPHEDRONE
MEPRYLCAINE
METHAPHIT
METHAPYRILENE
MEXILETINE An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
MEXILETINE HYDROCHLORIDE
MRS 2219
N-DESALKYLQUETIAPINE
OLICERIDINE
OLVANIL
OXETHAZAINE
PALONOSETRON HYDROCHLORIDE
PAPAVEROLINE
PENICILLIN V BENZATHINE
PI-CLONIDINE
PIMETHIXENE
PIPERIDOLATE
PITOLISANT
PNU-99194A
PRIDINOL
PRIDINOL METHANESULFONATE
PRIDOPIDINE
PROADIFEN
PROTRIPTYLINE An organic tricyclic compound that has formula C19H21N.
PYRANTEL
ROPINIROLE An indolone that has formula C16H24N2O.
RS 39604 An aromatic ether that is the 3,5-dimethoxybenzyl derivative of N-(2-{4-[3-(4-amino-5-chloro-2-hydroxyphenyl)-3-oxopropyl]piperidin-1-yl}ethyl)methanesulfonamide. A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and alpha1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies.
SC-19220
SNC80
SOLANIDINE
SPARTEINE A quinolizidine alkaloid fundamental parent that has formula C15H26N2.
TERBINAFINE
TETRABENAZINE
THONZONIUM
TIOTIDINE
TRIFLUPERIDOL
TROPISETRON
U50488 A monocarboxylic acid amide obtained by formal condensation between the carboxy group of 3,4-dichlorophenylacetic acid and the secondary amino group of (1R,2R)-N-methyl-2-(pyrrolidin-1-yl)cyclohexanamine
ULOTARONT
UMECLIDINIUM BROMIDE/VILANTEROL
UPADACITINIB
VALBENAZINE
VERNAKALANT
VESAMICOL
VILOXAZINE
VORTIOXETINE HYDROBROMIDE
ZOLANTIDINE
12-IMIDAZOLYL-1-DODECANOL
ACETAMINOPHEN SULFATE
METACETAMOL
PERFLUBRON
PHENETHYL ISOCYANATE
PHENETHYLISOTHIOCYANATE
VALERIAN ROOT EXTRACT
COMPOUND 4 [PMID: 16495056]
EBASTINE
(+/-)-PENTAACETYLCATECHIN
(R)-MELPHALAN
12-HYDROXY-4,4-BISNOR-4,8,11,13-PODOCARPATETRAEN-3-ONE
12A-HYDROXY-5-DEOXYDEHYDROMUNDUSERONE
2,4,6-TRIHYDROXYACETOPHENONE
2- (2,6-DIMETHOXYPHENOXYETHYL)AMINOMETHYL-1,4-BENZODIOXANE HYDROCHLORIDE (WB 4101)
2-METHOXY-5 (6)EPOXY-TETRAHYDROCARYOPHYLLENE
2-METHYL GRAMINE
3',4'-DIMETHOXYFLAVONE
3,7-DIMETHOXYFLAVONE
3-HYDROXY-3',4'-DIMETHOXYFLAVONE
4'-HYDROXY-FLAVANONE
4,2',4',6'-TETRAHYDROXYCHALCONE
4,4'-METHYLENEDIANILINE
4,4'-THIODIANILINE
5,7-DIHYDROXY-4-METHYLCOUMARIN
5,7-DIMETHOXYISOFLAVONE
6-METHYLFLAVONE
7,3'-DIMETHOXYFLAVONE
7-OXOCALLITRISIC ACID, METHYL ESTER
8,2'-DIMETHOXYFLAVONE
ACACETIN DIACETATE
ACRISORCIN
ALAPROCLATE
ALLANTODAPSONE
ALTANSERIN
ALTHIAZIDE
AMG-337
AMPEROZIDE
ARTHONIOIC ACID
ATORVASTATIN LACTONE
ATRANORIN
AVI-4557
AZELASTINE HYDROCHLORIDE
BENZPIPERYLON
BERBAMINE An isoquinoline that has formula C37H40N2O6.
BERGAPTOL
BIPHENYL-4-AMINE
BLONANSERIN
BMS-536924
CANAVANINE
CARMOFUR
CAULIBUGULONE D
CHELIDONINE (+)
CHEMBL:CHEMBL124267
CHEMBL:CHEMBL1256182
CHEMBL:CHEMBL1256868
CHEMBL:CHEMBL137498
CHEMBL:CHEMBL1397308
CHEMBL:CHEMBL15134
CHEMBL:CHEMBL1572261
CHEMBL:CHEMBL1605605
CHEMBL:CHEMBL174588
CHEMBL:CHEMBL184074
CHEMBL:CHEMBL220087
CHEMBL:CHEMBL225869
CHEMBL:CHEMBL272682
CHEMBL:CHEMBL309917
CHEMBL:CHEMBL39221
CHEMBL:CHEMBL422942
CHEMBL:CHEMBL453384
CHEMBL:CHEMBL462731
CHEMBL:CHEMBL484662
CHEMBL:CHEMBL502242
CHEMBL:CHEMBL590670
CHEMBL:CHEMBL74675
CHEMBL:CHEMBL74913
CHLORPYRIFOS An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
CHOLINE CHLORIDE
CILOSTAMIDE
CINALUKAST 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.
CITROPTEN
CL-976
CLEBOPRIDE MALEATE
CLINDAMYCIN A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic.
CLOPERASTINE HYDROCLORIDE
COBICISTAT
COMPOUND 1A [PMID: 18573659]
CORALYNE
DARUNAVIR
DEOXYSAPPANONE B TRIMETHYL ETHER
DERRUBONE
DERRUSNIN
DERRUSTONE
DICHLORODIPHENYLDICHLOROETHYLENE
DIHYDROXYBERGAMOTTIN
DIMETHYL GAMBOGATE
DIMETHYLPINOCEMBRIN
DIMPYLATE
DIRLOTAPIDE
DROFENINE HYDROCHLORIDE
ELEMICIN
ELIPRODIL
ERIBULIN MESYLATE
ETHAVERINE HYDROCHLORIDE
ETHYL ETHER
EUGENYL BENZOAT
EUPARIN
FENTHION An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.
FLOPROPIONE
FOSAMPRENAVIR
GANGALEOIDIN
GANGLEOIDIN ACETATE
GSK369796
GW0742X
HARMOL HYDROCHLORIDE
HYDRALAZINE HYDROCHLORIDE
HYDROXYCAMPTOTHECIN
ISOBERGAPTENE
ISOEUGENITOL
ISOKOBUSONE
ISOPIMPINELLIN A psoralen that has formula C13H10O5.
ISOQUINE DIHYDROCHLORIDE
IVABRADINE
IXABEPILONE
L741742
LECANORIC ACID
LEVISOPRENALINE
LURBINECTEDIN
MACROLIDE ANTIBIOTIC
MEBEVERINE HYDROCHLORIDE
MEK1/2 INHIBITOR
MICAFUNGIN
MORICIZINE
MUNDULONE
N-HISTIDYL-2-AMINONAPHTHALENE (BETANA)
NAFTIDROFURYL
NECROSTATIN-1
NIALAMIDE
NITROMIDE
NONOXYNOL-9
OKADAIC ACID A polycyclic ether that has formula C44H68O13.
OMAVELOXOLONE
ONONETIN
ORSELLINIC ACID
ORSELLINIC ACID, ETHYL ESTER
OSTHOLE
OXICONAZOLE NITRATE
PACHYRRIZINE
PAEONOL A methoxybenzene that has formula C9H10O3.
PENTAMETHYLQUERCETIN
PENTOSALEN
PERAMPANEL
PHENMEDIPHAM
PHENOLPHTHALEIN A phenol that has formula C20H14O4.
PHENYL AMINOSALICYLATE
PICOTAMIDE
PILOCARPINE NITRATE
PIMPINELLIN
PIPERIDOLATE HYDROCHLORIDE
PIVAMPICILLIN
PRE-084
REBOXETINE
RESORCINOL MONOACETATE
RHETSININE
RILMENIDINE HEMIFUMARATE
RIPRETINIB
ROBUSTIC ACID
ROBUSTONE
RP67580
SAPPANONE A 7-METHYL ETHER
SAPPANONE A TRIMETHYL ETHER
SERICETIN DIACETATE
SOBUZOXANE
SULCONAZOLE NITRATE
TABIMORELIN
TDI-015051
TENELIGLIPTIN
THIAMYLAL SODIUM
THIOPENTAL SODIUM
TIPRANAVIR A pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor.
TOLUENE DIISOCYANATE
TOMELUKAST
TOXAPHENE A highly complex mixture of several hundred polychlorinated compounds obtained by chlorination of camphene to an overall chlorine content of 67-69% by weight and having an overall empirical formula of C10H10Cl8 (including optical isomers, it could theoretically contain over 32,000 congeners). Toxaphene was used from the mid-1940s as an agricultural insecticide (mostly in the USA, particularly on corn and soybeans). Usage increased with the phasing out of DDT in the 1970s and it became the most heavily manufactured pesticide in the US, but it is now banned as a result of concerns over its toxicity and carcinogenicity. It is estimated that total production since its first use was around half a million tons. In the environment, most of the components of toxaphene get metabolised, but from 10 to >100 resist biodegradation, depending on the medium and the specialisation of the enzyme system. Breathing, drinking or eating high levels of toxaphene can damage the lungs, kidneys, and nervous system.
TRIACETYLRESVERATROL
UMIFENOVIR
VESNARINONE
VILAZODONE HYDROCHLORIDE
XANTHONE The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9.
XANTHOXYLIN
[3H]WAY100635
POMEGRANATE JUICE
SHO-SAIKO-TO
4-HYDROXYCYCLOPHOSPHAMIDE A phosphorodiamide that consists of 2-amino-1,3,2-oxazaphosphinan-4-ol 2-oxide having two 2-chloroethyl groups attached to the exocyclic nitrogen.
AMPRENAVIR
ISAVUCONAZOLE
NALDEMEDINE
PROPOXYPHENE A racemate of the (1R,2R)- and (1S,2R)- diastereoisomers.
VARDENAFIL The sulfonamide resulting from formal condensation of the sulfo group of 4-ethoxy-3-(5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one-2-yl)benzenesulfonic acid and the secondary amino group of 4-ethylpiperazine.
CORTISONE ACETATE A corticosteroid hormone that has formula C23H30O6.
SOTICLESTAT
HET0016
TP0472993
BRINCIDOFOVIR
SESAMIN
COMPOUND 7 [PMID: 32302132]
COMPOUND 7C [PMID: 36414390]
COMPOUND 10 [PMID: 31663733]
ISAVUCONAZONIUM SULFATE
ANTI-DIABETIC AGENT
LYCOPENE An acyclic carotene commonly obtained from tomatoes and other red fruits.
TIRAPAZAMINE A member of the class of benzotriazines that is 1,2,4-benzotriazine carrying an amino substituent at position 3 and two oxido substituents at positions 1 and 4.
BAYCYSLT2
BAYU9773
COMPOUND 13E [PMID: 31811124]
COMPOUND 15B [PMID: 31811124]
CR-3465
ICI198615
IRALUKAST
LTC4
LTD4
LTE4
LY-2300559
MASILUKAST
N-METHYL LTC4
NEDOCROMIL
POBILUKAST
PRANLUKAST
SULUKAST
TRIPLE MODULATOR 10 [PMID: 29878767]
VERLUKAST
HAMI3379
ONO-2570366
[3H]LTC4
ATOVAQUONE
DH376
DO34
LEI105
RHC80267
HT-01
3-HYDROXYCOUMARIN
BENZOIC ACID A compound comprising a benzene ring core carrying a carboxylic acid substituent.
CHEMBL:CHEMBL164585
CHEMBL:CHEMBL492591
LUVADAXISTAT
DAPK INHIBITOR 13
ETAMICASTAT
NEPICASTAT
ZAMICASTAT
COMPOUND 13 [PMID: 37465299]
OICR-8268
YT47R
TEZACITABINE
DCLK1-IN-1
XMD8-92 A dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a [2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino substituent. It is an inhibitor of the BMK1 kinase pathway.
D-157495
CHEMBL:CHEMBL351569
COMPOUND 2E [PMID: 19013076]
FOSCARBIDOPA
PROSAVIN
DIAZOOXONORLEUCINE
PHENETHYL ISOTHIOCYANATE An isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties.
PHOTOSENSITIZING AGENT
TOPOISOMERASE INHIBITOR
CHEMBL:CHEMBL1491941
MALONIC ACID An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
COMPOUND 1 [PMID: 31477924]
COMPOUND 4 [PMID: 26191369]
COMPOUND 6J [PMID: 27219676]
COMPOUND 7K [PMID: 23521020]
DDR-IN-1
DDR1 INHIBITOR 7RH
MAB 3E3 [PMID: 22483115]
MAB PRTH-101
NVP-BHG712 ISOMER
RIPK3 INHIBITOR 18
COMPOUND 10B [PMID: 41766566]
SUPINOXIN
RBM2-1B
SKI II
AZD-7687
AZD7687
COMPOUND 23N [PMID: 24900877]
COMPOUND 5B [PMID: 25349648]
PF-04620110
PRADIGASTAT
T863
ERVOGASTAT
PF-07202954
AMINOSALICYLIC ACID
CH-1504
CH-4051
CHEMBL:CHEMBL22148
COMPOUND 9 [PMID: 15615544]
DIFLUNISAL An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
ICLAPRIM
METHOTREXATE SODIUM
PEMETREXED DIPOTASSIUM
PEMETREXED MONOHYDRATE
PEMETREXED TROMETHAMINE
PIRITREXIM
PRALATREXATE
TALOTREXIN
BRD9185
BREQUINAR
COMPOUND 19 [PMID: 35925768]
DSM421
DSM705
FARUDODSTAT
ORLUDODSTAT
S312
S416
TERIFLUNOMIDE
VIDOFLUDIMUS
(+/-)-WIEDENDIOL B
CHEMBL:CHEMBL456414
CHEMBL:CHEMBL459574
CHEMBL:CHEMBL461471
CHEMBL:CHEMBL514876
CHEMBL:CHEMBL517425
PROTECTED SIPHONODICTYAL C
MANOALIDE A sesterterpenoid isolated from the marine sponge Luffariella variabilis and which has been shown to exhibit inhibitory activity towards phospholipase A2.
CEPHALOSTATIN
ISOCOUMARIN NM-3
HTERT VACCINE V934/V935
BHQ-880
DKN-01
LEVOLEUCOVORIN
NERINETIDE
GDC-0134
AUTOLOGOUS ANTI-DLL3 CAR T-CELLS AMG 119
ROVALPITUZUMAB TESIRINE
DEMCIZUMAB
DILPACIMAB
ENOTICUMAB
MEDI-639
NAVICIXIZUMAB
BMN-044
CASIMERSEN
DELANDISTROGENE MOXEPARVOVEC
ETEPLIRSEN
GOLODIRSEN
SUVODIRSEN
VILTOLARSEN
BOMEDEMSTAT
CC-90011
GSK2879552
ALOBRESIB
BET INHIBITOR RO6870810
FT-1101
PLX51107
TROTABRESIB
ZEN-3694
ANTROQUINONOL An enone that is cyclohex-2-en-1-one substituted by a hydroxy group at position 4, methoxy groups at positions 2 and 3, a methyl group at position 6 and a (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl group at position 5 (the 4R,5R,6R stereoisomer). It is isolated from the solid-state fermented mycelium of the fungus Antrodia camphorata and has been found to exhibit potent cytotoxicity against a number of human cancer cell lines.
BENZANTHRONE
BISDEMETHOXYCURCUMIN
BROMO-DEAZA-SAH
CHEMBL:CHEMBL1490332
CHEMBL:CHEMBL2063052
CHEMBL:CHEMBL580076
CM-272
DAPHNORIN
DECITABINE AND CEDAZURIDINE
DEMETHOXYCURCUMIN A beta-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior.
GSK3685032
GUADECITABINE
HEXAHYDROCURCUMIN
MAHANINE
MG98
ORAL AZACITIDINE
PALIFOSFAMIDE
RODUCITABINE
SGI-1027
TETRAHYDROCURCUMIN A beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds.
ZEBULARINE
PINOMETOSTAT
COMPOUND 9 [PMID: 1738140]
QGC-001
ADENOSINE DEAMINASE INHIBITOR
ZALCITABINE
COMPOUND 13 [CHEN ET AL., 2016]
EPZ004777
SGC0946
CILASTATIN
CILASTATIN SODIUM
ALOGLIPTIN A piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of type 2 diabetes.
ALOGLIPTIN BENZOATE
ANAGLIPTIN
BEGELOMAB
BISEGLIPTIN
CARMEGLIPTIN
CETAGLIPTIN
COFROGLIPTIN
COMPOUND 1 [XIAO ET AL. 2014]
COMPOUND 24DD [PMID: 20684603]
COMPOUND 9 [PMID: 20718420]
DUTOGLIPTIN
EVOGLIPTIN
FOTAGLIPTIN
GEMIGLIPTIN
GOSOGLIPTIN
LINAGLIPTIN
MELOGLIPTIN
OMARIGLIPTIN
PRUSOGLIPTIN
SAXAGLIPTIN ANHYDROUS
SAXAGLIPTIN HYDROCHLORIDE
SITAGLIPTIN FUMARATE
SITAGLIPTIN HYDROCHLORIDE MONOHYDRATE
SITAGLIPTIN PHOSPHATE
TRELAGLIPTIN SUCCINATE
VALACYCLOVIR
VILDAGLIPTIN
ZY15557
UAMC00039
1G244
COMPOUND 18 [PMID: 15664838]
COMPOUND 42 [PMID: 37721854]
ICED-2
TOMINOSTAT
ENILURACIL
GIMERACIL
RO0094889
(+)-ADTN
(+)-BUTACLAMOL An organic heteropentacyclic compound that is 2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinoline substituted at position 3 by both hydroxy and tert-butyl groups.
(-)-STEPHOLIDINE
(R)-SCH-23390
2MESATP
A77636
AMINEPTIN
APOCIDEINE
CARPHENAZINE A propanone that has formula C24H31N3O2S.
CHEMBL:CHEMBL123349
CHEMBL:CHEMBL1256191
CHEMBL:CHEMBL305195
CHEMBL:CHEMBL542700
CHEMBL:CHEMBL63329
CHLORPROTHIXENE
DAS-431 IV
DEOXIEPINEPHRINE
DIHYDROERGOTAMINE MESYLATE
DROTRECOGIN ALFA
ECOPIPAM
ECOPIPAM HYDROCHLORIDE
EPINASTINE A benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.
ETILEVODOPA
IFENPRODIL
LOXAPINE A dibenzoxazepine that has formula C18H18ClN3O.
LY3154885
MESORIDAZINE
MEVIDALEN
MOLINDONE
N-PROPYLNORAPOMORPHINE
NIPECOTIC ACID
OPIPRAMOL
PALMITOYL-CARNITINE
PERGOLIDE MESYLATE
PHENAMIL
PHENYLTOLOXAMINE
PRECLAMOL
ROTIGOTINE
SCH-23390
SKF-38393
SKF-76783
SKF-82958
SKF-83959
TAVAPADON
UCM-1306
VINPOCETINE
XP21279
ZICRONAPINE
ZIMELDINE
[125I]SCH23982
[3H]TYRAMINE
(+)-S-14297
(+)-SCH-23390
(+)-UH232
5-OH-DPAT
7-TRANS-OH-PIPAT
ABAPERIDONE
ACETOPHENAZINE MALEATE
ADOPRAZINE
ALIZAPRIDE
APLINDORE
APLINDORE FUMARATE
ASENAPINE MALEATE
BENZQUINAMIDE HYDROCHLORIDE
BIFEPRUNOX
BL-1020
BRILAROXAZINE
BROMOPRIDE
CARIPRAZINE HYDROCHLORIDE
CARMOXIROLE An indolecarboxylic acid that is indole-5-carboxylic acid bearing an additional 4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl substituent at position 3. Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo.
CARPHENAZINE MALEATE
COMPOUND 3 [PMID: 23134120]
DEXPRAMIPEXOLE
DIHYDROERGOTOXINE
DOCARPAMINE
DOPEXAMINE
FLUPHENAZINE DECANOATE
FLUPHENAZINE ENANTHATE
HALOPERIDOL LACTATE
HS665
JNJ-37822681
LOXAPINE HYDROCHLORIDE
LOXAPINE SUCCINATE
LP-12
LP-211
LP-44
LUMATEPERONE
MAZAPERTINE SUCCINATE
MESORIDAZINE BESYLATE
ML321
MLS1547
MOLINDONE HYDROCHLORIDE
NAFADOTRIDE A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, preferential dopamine D3 receptor antagonist, centrally active upon systemic administration.
OLANZAPINE PAMOATE
ONZIGOLIDE
ORDOPIDINE
PALIPERIDONE PALMITATE
PERAZINE
PEROSPIRONE
PF-00217830
PIPOTHIAZINE
PRAMIPEXOLE A member of the class of benzothiazoles that is 4,5,6,7-tetrahydro-1,3-benzothiazole in which the hydrogens at the 2 and 6-pro-S-positions are substituted by amino and propylamino groups, respectively.
PRAMIPEXOLE DIHYDROCHLORIDE
PROCHLORPERAZINE MALEATE
QUINAGOLIDE
QUINELORANE
QUINPIROLE A pyrazoloquinoline that is (4aR,8aR)-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]quinoline substituted by a propyl group at position 5. It acts as a dopamine agonist.
R-VK4-40
REMOXIPRIDE HYDROCHLORIDE
ROPINIROLE HYDROCHLORIDE
SARIZOTAN
SARIZOTAN HYDROCHLORIDE
SB-773812
SB269652
SERIDOPIDINE
SUMANIROLE
TALIPEXOLE
THIETHYLPERAZINE MALATE
THIETHYLPERAZINE MALEATE
THIOTHIXENE HYDROCHLORIDE
TIAPRIDE
TRAZPIROBEN
UMESPIRONE
UNC0006
UNC9975
UNC9994
VERALIPRIDE
YKP-1358
ZIPRASIDONE HYDROCHLORIDE
ZIPRASIDONE MESYLATE
[3H]7-OH-DPAT
[3H]NEMONAPRIDE
[3H]PD128907
(+)-AJ76
ABT-925
CHEMBL:CHEMBL1255656
CHEMBL:CHEMBL1256698
CHEMBL:CHEMBL1256778
CHEMBL:CHEMBL1256876
CHEMBL:CHEMBL544115
MESDOPETAM
NGB 2904
PF-592379
PG01037
PRECLAMOL HYDROCHLORIDE
S33084
SB 277011-A
TALIPEXOLE HYDROCHLORIDE
A-381393
A412997
ABT-670
CLOTHIAPINE
L745870
ML398
SONEPIPRAZOLE
U101958
[125I]L750667
BETA-ERGOCRIPTINE
CHEMBL:CHEMBL1333386
CHEMBL:CHEMBL601167
SUCCIMER
DUTPASE/DPD INHIBITOR TAS-114
BENZIMIDAZOLE A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings.
COMPOUND 2-2C [PMID: 32003560]
COMPOUND 3B [PMID: 23454515]
COMPOUND 68 [PMID: 24900699]
COMPOUND 72 [WO2013026806]
GNF2133
GNF4877
AZ191
COMPOUND 5B [PMID: 24900464]
LEUCETTINE L41
EDIFOLIGIDE
LARGAZOLE
PIBENZIMOL
COMPOUND 22 [PMID: 19899765]
DAGLUTRIL
KC-12615
PD159790
SLV-334
COMPOUND 1 [PMID: 18507370]
S136492
ECTODYSPLASIN A2
ECTODYSPLASIN A1
ANTIPLATELET AGENT
LANREOTIDE ACETATE
OXYGEN THERAPY
THIOURACIL A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.
APROCITENTAN
ATRASENTAN
ATRASENTAN HYDROCHLORIDE
AVOSENTAN
BMS-193884
BOSENTAN ANHYDROUS
BQ-123
BQ123
CLAZOSENTAN
DARUSENTAN
DIOSUXENTAN
EDONENTAN ANHYDROUS
ENDOTHELIN-1
ENDOTHELIN-2
ENRASENTAN
FR139317
GETAGOZUMAB
NEBENTAN
PD-156707
PD164333
SARAFOTOXIN S6B
SB234551
SITAXENTAN
SITAXENTAN SODIUM
SOVATELTIDE
TBC-3711
TEZOSENTAN
ZIBOTENTAN
[125I]ET-1 (HUMAN, MOUSE, RAT)
[125I]ET-2 (HUMAN)
[125I]PD151242
[125I]PD164333
[125I]SARAFOTOXIN S6B
[18F]ET-1 (HUMAN, MOUSE, RAT)
[3H]BQ123
[3H]S0139
A192621
BQ 3020
BQ788
ENDOTHELIN-3
K-8794
RES7011
RG-7636
RO 46-8443
SARAFOTOXIN S6C
[125I]BQ3020
[125I][ALA1,3,11,15]ET-1
[ALA1,3,11,15]ET-1
A-395
AZ14117230
MAK683
POCIREDIR
SPARSOMYCIN
PLITIDEPSIN
CINTREDEKIN BESUDOTOX
DENILEUKIN DIFTITOX
LACTIMIDOMYCIN
LMB-1
LMB-100
LMB-2
LMB-7
LMB-9
OPORTUZUMAB MONATOX
SS1(DSFV)-PE38
COMPOUND 34 [PMID: 20189382]
SEPHB4-HSA
EPIDERMAL GROWTH FACTOR
NIMOTUZUMAB
PARSATUZUMAB
AEE788
AFATINIB DIMALEATE
ALLITINIB
ALOE-EMODIN
AMIVANTAMAB
AMPHIREGULIN
ANTI-EGFR MONOCLONAL ANTIBODY EMD 55900
ANTI-EGFR MONOCLONAL ANTIBODY GT-MAB 5.2-GEX
ANTI-EGFR MONOCLONAL ANTIBODY SYN004
ANTI-EGFR/HER2/HER3 MONOCLONAL ANTIBODY MIXTURE SYM013
ANTI-EGFRVIII ANTIBODY DRUG CONJUGATE AMG 595
ANTI-EGFRVIII IMMUNOTOXIN MR1-1
ANTI-ERBB3 MONOCLONAL ANTIBODY AV-203
ANTI-MET MONOCLONAL ANTIBODY MIXTURE SYM015
ANTI-MET/EGFR MONOCLONAL ANTIBODY LY3164530
ANTI-PD1 MONOCLONAL ANTIBODY
ASANDEUTERTINIB
AUMOLERTINIB
AV-412
AZ5104
AZD-4769
BAFISONTAMAB
BEFOTERTINIB
BETACELLULIN
BI-4020
BI-4142
BIZROLERTINIB
BMS-599626
BMS-690514
BPIQ-I
C34 [ZHU ET AL., 2023]
CETUXIMAB SAROTALOCAN
CETUXIMAB SAROTALOCAN SODIUM
CH7233163
CHEMBL:CHEMBL1077773
CHEMBL:CHEMBL1078000
CHEMBL:CHEMBL1914653
CIPATINIB
COMPOUND 17B [PMID: 35286086]
COMPOUND 18J [PMID: 35446588]
COMPOUND 52 [PMID: 36749735]
COMPOUND 56 [PMID: 8568816]
COMPOUND 6G [PMID: 30633509]
CUDC-101
DACOMITINIB
DACOMITINIB ANHYDROUS
DATOPOTAMAB DERUXTECAN
DEPATUXIZUMAB
DEPATUXIZUMAB MAFODOTIN
DOSIMERTINIB
DULIGOTUZUMAB
EAI045
EGF epidermal growth factor|This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
EGFR INHIBITOR
EGFR INHIBITOR 57
EGFR/ERBB-2 INHIBITOR
EGFR/ERBB-2/ERBB-4 INHIBITOR
EMUPERTINIB
EP26
EPIGEN
EPIREGULIN
EPITINIB
EXAMPLE 10 [CN110740999A]
FALNIDAMOL
FIRMONERTINIB
FUTUXIMAB
G-QUADRUPLEX STABILIZER BMVC
GC1118
GOZANERTINIB
GRACILIN A
GRACILIN J
HB-EGF
ICOTINIB HYDROCHLORIDE
IMGATUZUMAB
INDIUM-111
JAK3 INHIBITOR II
JBJ-04-125-02
JBJ-09-063
JND3229
JNJ-26483327
KBP5209
LAPATINIB DITOSYLATE
LAPRITUXIMAB EMTANSINE
LAZERTINIB
LAZERTINIB MESYLATE
LIMERTINIB
LOSATUXIZUMAB VEDOTIN
MAB-425
MATUZUMAB
MAVELERTINIB
MDX-214
MDX-447
METHYLCURCUMIN
MIFANERTINIB
MM-151
MOBOCERTINIB
MOBOCERTINIB SUCCINATE
MODOTUXIMAB
MS154
MS39
MULTIKINASE INHIBITOR AEE788
NAQUOTINIB
NAZARTINIB
NECITUMUMAB
NERATINIB MALEATE
OLMUTINIB
ORANTINIB
ORIC-114
OSIMERTINIB MESYLATE
PACRITINIB
PAN-HER KINASE INHIBITOR AC480
PATRITUMAB
PD 158780
PD 174265
PD-0166285 HYDROCHLORIDE
PELITINIB
PETOSEMTAMAB
PF-05230907
PF-06459988
PIMURUTAMAB
PIROTINIB
PKI166
POZIOTINIB
PRUVONERTINIB
PUQUITINIB MESYLATE DIHYDRATE
PYROTINIB
RALIMETINIB
REZIVERTINIB
RINDOPEPIMUT
ROCILETINIB
ROGARATINIB
S-222611
SELATINIB
SERIBANTUMAB
SEVABERTINIB
SH-1028
SILEVERTINIB
SIMOTINIB
STX-241
TAK-285
TARLOXOTINIB
TELISOTUZUMAB VEDOTIN
TESEVATINIB
TGF&ALPHA;
THELIATINIB
TIGOZERTINIB
TOMUZOTUXIMAB
TQB3804
TUCATINIB
TUXOBERTINIB
VARLITINIB
XILIERTINIB
YUANHUADINE
ZALUTUMUMAB
ZIPALERTINIB
ZM-306416
ZONGERTINIB
ZORIFERTINIB
CHEMBL:CHEMBL1800368
CHEMBL:CHEMBL78920
COMPOUND 6EE [PMID: 22364528]
DAPRODUSTAT
DDO-3055
ENARODUSTAT
FG-2216
IOX1
IOX2
MOLIDUSTAT
N-OXALYLGLYCINE
ROXADUSTAT
VADADUSTAT
DESIDUSTAT
BRIVOLIGIDE
GENIPIN An iridoid monoterpenoid that has formula C11H14O5.
A-366
MS8709
UNC0638
UNC0642
&ALPHA;&BETA;-MEATP
(+)-NORFENFLURAMINE
(+)-TAXIFOLIN
(4-CHLOROPHENYL)(MORPHOLINO)METHANETHIONE
(S)-WILLARDIINE
0-HEXYL-1,3-DIAMINE-PLATINUM 2,2-DICHLORIDE
1-AMINOCYCLOPROPANE CARBOXYLIC ACID
2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEPTANOIC ACID [1-(2-HYDROXYMETHYL-PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL]-AMIDE
4-BENZYLOXYANILINE
5-BENZYLOXYTRYPTAMINE
5-HYDROXYINDOLEACETIC ACID
ACETAMIDE A member of the acetamides that has formula C2H5NO.
AIDA axin interactor, dorsalization associated|
AMANTADINE HYDROCHLORIDE
AMARANTH
AP-7
APAZONE
ARUNDINE
AZEPEXOLE
BENANSERIN HYDROCHLORIDE
BENZOPHENONE-THIOSEMICARBAZONE
BENZYL NICOTINATE
BETAINE HYDROCHLORIDE
BISMUTH SUBSALICYLATE A bismuth salt of salicylic acid.
BRD9539
BROMPHENIRAMINE Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
BRONOPOL
CACA
CAFFEIC ACID A hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common.
CEFAZOLIN A cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups.
CGP-71683A
CGP53353
CHAETOCIN
CHELERYTHRINE CHLORIDE
CHELIDAMIC ACID
CHEMBL:CHEMBL1172228
CHEMBL:CHEMBL118378
CHEMBL:CHEMBL1200792
CHEMBL:CHEMBL1200902
CHEMBL:CHEMBL1232076
CHEMBL:CHEMBL1236602
CHEMBL:CHEMBL1256174
CHEMBL:CHEMBL1256186
CHEMBL:CHEMBL1256484
CHEMBL:CHEMBL1256510
CHEMBL:CHEMBL1256689
CHEMBL:CHEMBL1256776
CHEMBL:CHEMBL1256797
CHEMBL:CHEMBL1256863
CHEMBL:CHEMBL1256865
CHEMBL:CHEMBL1256885
CHEMBL:CHEMBL1256920
CHEMBL:CHEMBL1256984
CHEMBL:CHEMBL1256995
CHEMBL:CHEMBL129841
CHEMBL:CHEMBL1308346
CHEMBL:CHEMBL1312050
CHEMBL:CHEMBL1315166
CHEMBL:CHEMBL1328677
CHEMBL:CHEMBL1331995
CHEMBL:CHEMBL1369632
CHEMBL:CHEMBL1385558
CHEMBL:CHEMBL1406487
CHEMBL:CHEMBL1448793
CHEMBL:CHEMBL1449731
CHEMBL:CHEMBL1459149
CHEMBL:CHEMBL1478462
CHEMBL:CHEMBL1483413
CHEMBL:CHEMBL1509789
CHEMBL:CHEMBL1510164
CHEMBL:CHEMBL1534034
CHEMBL:CHEMBL1545737
CHEMBL:CHEMBL1605629
CHEMBL:CHEMBL1728978
CHEMBL:CHEMBL193093
CHEMBL:CHEMBL198666
CHEMBL:CHEMBL2094456
CHEMBL:CHEMBL211042
CHEMBL:CHEMBL227959
CHEMBL:CHEMBL2374078
CHEMBL:CHEMBL264684
CHEMBL:CHEMBL317356
CHEMBL:CHEMBL338314
CHEMBL:CHEMBL343002
CHEMBL:CHEMBL344127
CHEMBL:CHEMBL387632
CHEMBL:CHEMBL388979
CHEMBL:CHEMBL403741
CHEMBL:CHEMBL411085
CHEMBL:CHEMBL411644
CHEMBL:CHEMBL431504
CHEMBL:CHEMBL444928
CHEMBL:CHEMBL451722
CHEMBL:CHEMBL460574
CHEMBL:CHEMBL464538
CHEMBL:CHEMBL467987
CHEMBL:CHEMBL475813
CHEMBL:CHEMBL476025
CHEMBL:CHEMBL492528
CHEMBL:CHEMBL512649
CHEMBL:CHEMBL515495
CHEMBL:CHEMBL520992
CHEMBL:CHEMBL525106
CHEMBL:CHEMBL525888
CHEMBL:CHEMBL528119
CHEMBL:CHEMBL529741
CHEMBL:CHEMBL530664
CHEMBL:CHEMBL530698
CHEMBL:CHEMBL532143
CHEMBL:CHEMBL532412
CHEMBL:CHEMBL533954
CHEMBL:CHEMBL534214
CHEMBL:CHEMBL536166
CHEMBL:CHEMBL537045
CHEMBL:CHEMBL541585
CHEMBL:CHEMBL545184
CHEMBL:CHEMBL546580
CHEMBL:CHEMBL547175
CHEMBL:CHEMBL547269
CHEMBL:CHEMBL547304
CHEMBL:CHEMBL547656
CHEMBL:CHEMBL547833
CHEMBL:CHEMBL54943
CHEMBL:CHEMBL553503
CHEMBL:CHEMBL559934
CHEMBL:CHEMBL565893
CHEMBL:CHEMBL576781
CHEMBL:CHEMBL577222
CHEMBL:CHEMBL578896
CHEMBL:CHEMBL579742
CHEMBL:CHEMBL582694
CHEMBL:CHEMBL582697
CHEMBL:CHEMBL582737
CHEMBL:CHEMBL582764
CHEMBL:CHEMBL583150
CHEMBL:CHEMBL584452
CHEMBL:CHEMBL585269
CHEMBL:CHEMBL586029
CHEMBL:CHEMBL586195
CHEMBL:CHEMBL586982
CHEMBL:CHEMBL589479
CHEMBL:CHEMBL589670
CHEMBL:CHEMBL589734
CHEMBL:CHEMBL589924
CHEMBL:CHEMBL590666
CHEMBL:CHEMBL591630
CHEMBL:CHEMBL591864
CHEMBL:CHEMBL592558
CHEMBL:CHEMBL592834
CHEMBL:CHEMBL596631
CHEMBL:CHEMBL596836
CHEMBL:CHEMBL597246
CHEMBL:CHEMBL598268
CHEMBL:CHEMBL599957
CHEMBL:CHEMBL600173
CHEMBL:CHEMBL600298
CHEMBL:CHEMBL600701
CHEMBL:CHEMBL600769
CHEMBL:CHEMBL601322
CHEMBL:CHEMBL601367
CHEMBL:CHEMBL601547
CHEMBL:CHEMBL601605
CHEMBL:CHEMBL601968
CHEMBL:CHEMBL602408
CHEMBL:CHEMBL602763
CHEMBL:CHEMBL602923
CHEMBL:CHEMBL603024
CHEMBL:CHEMBL603739
CHEMBL:CHEMBL606456
CHEMBL:CHEMBL609036
CHLOROETHYLCLONIDINE
CHLOROGENIC ACID A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin.
CLINAFLOXACIN
CLORINDIONE
COCLAURINE
CROCIN
CV-3988
CYCLOPHOSPHAMIDE A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.
CYCLOPIAZONIC ACID
CYSTAMINE DIHYDROCHLORIDE
DANTHRON
DEBRISOQUIN SULFATE
DECYLUBIQUINONE
DIBROMOTYROSINE
DIHYDRALAZINE
DIHYDREXIDINE HYDROCHLORIDE
DMPP
DOXYLAMINE A tertiary amine that has formula C17H22N2O.
E-64C
ENOXAMAST
ENROFLOXACIN
ERGOCRISTINE Ergotaman bearing benzyl, hydroxy, and isopropyl groups at the 5', 12' and 2' positions, respectively, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid.
ETHAMSYLATE
ETHIDIUM The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
FENCLONINE
FOSFONET
GABACULINE HYDROCHLORIDE
GAMMA-AMINOBUTYRIC ACID A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
GLUTAMIC ACID
GLUTAMIC ACID HYDROCHLORIDE
GW3965
HARPAGOSIDE
HERACLENOL
HYDROXYZINE PAMOATE
HYPEROSIDE
HYPOTAURINE An aminosulfinic acid comprising ethylamine having the sulfo group at the 2-position.
IBUFENAC
IMETIT DIHYDROBROMIDE
IMIDAZOLE ACETIC ACID
INDIGOTINDISULFONATE
IODO-WILLARDIINE
IODOPHTHALEIN
IODOQUINOL
IPRONIAZID PHOSPHATE
L-CYSTEINE SULPHINIC ACID
L-MIMOSINE
LAVENDUSTIN A
LAVENDUSTIN C
LINSIDOMINE
LISINOPRIL HYDRATE
LOMEFLOXACIN
LONIDAMINE A member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively.
METAPHIT METHANESULFONATE
METHYLMALONIC ACID A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
METHYLSELENOCYSTEINE
METRAZOLINE OXALATE
MIZORIBINE
N-ACETYLSEROTONIN A member of the class of hydroxyindoles that is the N-acetyl derivative of serotonin.
N-[3H]METHYLHISTAMINE
NALOXONE BENZOYLHYDRAZONE
NARINGIN
NICOTINE BITARTRATE
NMDA
NOLATREXED
NOMIFENSINE
NOR-BINALTORPHIMINE
OLPRINONE
ORPHENADRINE CITRATE
OXOTREMORINE METHIODIDE
PAXILLINE An organooxygen compound that has formula C27H33NO4.
PHENAZINE
PHENAZINE-1-CARBOXYLIC ACID
PHENINDIONE
PHOSMET A phthalimide that has formula C11H12NO4PS2.
PIRENZEPINE HYDROCHLORIDE
PORFIROMYCIN
PROFLAVINE
PROPYLENE GLYCOL MONOSTEARATE
PUTRESCINE DIHYDROCHLORIDE
QUISQUALIC ACID An alpha-amino acid that has formula C5H7N3O5.
RAZOXANE
RISEDRONIC ACID A pyridine that has formula C7H11NO7P2.
RO31-8220
RUFLOXACIN
SALICYLHYDROXAMIC ACID
SALSOLINOL HYDROBROMIDE
SALUBRINAL
SANGUINARIUM CHLORIDE
SB269970
SCARLET RED
SERINE, D-
SEROTONIN HYDROCHLORIDE
STREPTOMYCIN A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class
SULFAPYRIDINE
SULINDAC SULFOXIDE
SYMCLOSENE
THIOGUANOSINE
THIOSALICYLIC ACID
THYMOL IODIDE
TINORIDINE
TRIPROLIDINE
TRITIOZINE
TROLOX
UNC0321
VANILLYLMANDELIC ACID An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.
[3H]8-OH-DPAT
[3H]AMPA
CHEMBL:CHEMBL534675
COMPOUND 27 [PMID: 19854648]
INDIRUBIN DERIVATIVE E804
PKR INHIBITOR
RICIN
CHEMBL:CHEMBL2171124
GSK2606414
GSK2656157
HC-5404
COMPOUND 39 [PMID: 36127295]
COMPOUND A127 [WO2013110309]
HC-7366
NXP800
HIPPURISTANOL
SILVESTROL
LY2275796
CHEMBL:CHEMBL585964
SNS01-T
.ALPHA.1-PROTEINASE INHIBITOR HUMAN
ALPHA 1-ANTITRYPSIN
ALVELESTAT
BAY-678
CHEMBL:CHEMBL310871
CHF6333
COMPOUND 10F [PMID: 24556381]
COMPOUND 10L [PMID: 24556381]
DEPELESTAT
LONODELESTAT
SIVELESTAT SODIUM
SYMPLOSTATIN 5
TIPRELESTAT
DEHYDROMUTACTIN
VONAPANITASE
VOLASERTIB
CAROTUXIMAB
FIRIBASTAT
ENPP1 INHIBITOR 27
ENPP1 INHIBITOR 29F
ISM5939
VIZENPISTAT
BI-2545
BIO-32546
CAMBRITAXESTAT
CHEMBL:CHEMBL1089321
CHEMBL:CHEMBL1092743
CHEMBL:CHEMBL1093490
CHEMBL:CHEMBL1630084
CHEMBL:CHEMBL483302
EXAMPLE 1.11 [WO2014139978]
EXAMPLE 2 [WO2013054185]
PF-8380
X-165
ZIRITAXESTAT
AGS-16C3F
ANTI-ENPP3/MMAF ANTIBODY-DRUG CONJUGATE AGS-16M8F
PERENOSTOBART
PSB-0963
PSB-6426
C646
CHEMBL:CHEMBL404916
GARCINOL A monoterpenoid that has formula C38H50O6.
H3-COA-20
LYS-COA
CASDATIFAN
HALICLONADIAMINE
NEOPETROFORMYNE A
NVP-DFF332
PT2385
PUUPEHENONE
ADECATUMUMAB
ALUMINUM SULFATE ANHYDROUS
ALVAC VACCINE
CITATUZUMAB BOGATOX
EDRECOLOMAB
IGN-101
IGN101
INCOMPLETE FREUND'S ADJUVANT
ING-1
KEYHOLE LIMPET HEMOCYANIN
MINERAL OIL
MOC31-PE
TUCOTUZUMAB CELMOLEUKIN
COMPOUND 20 [PMID: 23489211]
COMPOUND 66 [PMID: 19788238]
CILOFEXOR
DORSOMORPHIN A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine which is substituted at positions 3 and 6 by pyridin-4-yl and p-[2-(piperidin-1-yl)ethoxy]phenyl groups, respectively. It is a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase, EC 2.7.11.31) and a selective inhibitor of bone morphogenetic protein (BMP) signaling.
LITHOGLYCOCHOLATE
MEDI-547
NVP-BHG712
FIBATUZUMAB
IFABOTUZUMAB
KB-004
JI-101
AR-9281
ALLOIN
BI-1935
COMPOUND G1 [PMID: 36689364]
DIFLAPOLIN
DUAL SEH/FAAH INHIBITOR 11
EC5026
GSK2256294
INHIBITOR M9 [PMID: 38236416]
LEMUPLAMOR
MPPA
PF750
SWE101
RECOMBINANT INTERLEUKIN-1-ALPHA
EFEPOETIN ALFA
EPOETIN BETA
EPOETIN DELTA
EPOETIN THETA
ERYTHROPOIESIS-STIMULATING AGENT
METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
PEGINESATIDE
PEGINESATIDE ACETATE
HALOFUGINONE
CHEMBL:CHEMBL531269
CHEMBL:CHEMBL587247
CLAVULANIC ACID
COMPOUND 17 [PMID: 23916253]
COMPOUND 2G [PMID: 27390066]
COMPOUND 3V [PMID: 27390066]
SCOPOLETIN A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6.
UMBELLIFERONE
SECUKINUMAB
ADO-TRASTUZUMAB EMTANSINE
ANTHRAQUINONE ANALOGUE
ANTI-HER2 ANTIBODY-DRUG CONJUGATE MEDI4276
ANVATABART OPADOTIN
CIMAGLERMIN ALFA
CP-724714
DISITAMAB VEDOTIN
ELACESTRANT
ELATIPEPIMUT-S
FAM-TRASTUZUMAB DERUXTECAN-NXKI
GANCOTAMAB
GLYCOOPTIMIZED TRASTUZUMAB-GEX
HEMAY-022
HER2 ECD+TM VIRUS-LIKE REPLICON PARTICLES VACCINE AVX901
HER2-TARGETED LIPOSOMAL DOXORUBICIN HYDROCHLORIDE MM-302
HLX22
HSP90 INHIBITOR
IMLUNESTRANT
INAVOLISIB
KN-026
LAPULEUCEL-T
MARGETUXIMAB
MDX-210
MM-111
MUBRITINIB
MULTI-NEO-EPITOPE VACCINE OSE 2101
MVA-BN-HER-2
NAKIJIQUINONE I
NAKIJIQUINONES G
NAKIJIQUINONES H
NELIPEPIMUT-S
THERAPEUTIC AUTOLOGOUS DENDRITIC CELLS
TIPIRACIL
TIPIRACIL / TRIFLURIDINE
TRASTUZUMAB BOTIDOTIN
TRASTUZUMAB DERUXTECAN
TRASTUZUMAB DUOCARMAZINE
TRASTUZUMAB EMTANSINE
TRIFLURIDINE
TYRPHOSTIN AG 879
VACCINE ADJUVANT
ZANIDATAMAB
ZENOCUTUZUMAB
AMG-888
ANTI-ERBB3 MONOCLONAL ANTIBODY CDX-3379
ANTI-ERBB3 MONOCLONAL ANTIBODY REGN1400
ANTI-HER3 MONOCLONAL ANTIBODY GSK2849330
AV-203
CDX-3379
ELGEMTUMAB
ELISIDEPSIN
HER2 INHIBITOR CP-724,714
ISTIRATUMAB
LUMRETUZUMAB
NEUREGULIN-1
NEUREGULIN-2
PATRITUMAB DERUXTECAN
TX1-85-1
TX2-121-1
NEUREGULIN-3
NEUREGULIN-4
FEPIXNEBART
MITONAFIDE
N-ACETYLASPARTIC ACID
SEROTONIN A primary amino compound that is the 5-hydroxy derivative of tryptamine.
COMPOUND 34 [PMID: 24749861]
TEMELIMAB
1-HYDROXY-6-(4-HYDROXY-PHENYL)-1-PHENYL-HEXAN-3-ONE (ENANTIOMERIC MIX)
16&ALPHA;-HYDROXYESTRONE
4-METHYLBENZOIC ACID METHYL ESTER
4-TRIETHYLGERMYLPHENOL
AC-186
ACOLBIFENE
ACRYLAMIDE A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
AFIMOXIFENE A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen.
ALFADEX
ALLYLESTRENOL
AMCENESTRANT
AROMATASE INHIBITOR
ARSANILIC ACID An organoarsonic acid that has formula C6H8AsNO3.
ARZOXIFENE
BAZEDOXIFENE
BAZEDOXIFENE ACETATE
BORIC ACID A member of the boric acids that has formula BH3O3.
BRILANESTRANT
CAMIZESTRANT
CHEMBL:CHEMBL1091535
CHEMBL:CHEMBL1222035
CHEMBL:CHEMBL1432305
CHEMBL:CHEMBL1523215
CHEMBL:CHEMBL2071180
CHEMBL:CHEMBL2313444
CHEMBL:CHEMBL2313445
CHEMBL:CHEMBL354663
CHEMBL:CHEMBL384441
CHEMBL:CHEMBL503990
CHEMBL:CHEMBL85826
CHF 4227
CHF4227
CLOMIPHENE A tertiary amine that has formula C26H28ClNO.
COMPOUND 5 [PMID: 40393772]
COUMESTROL A member of the class of coumestans that is coumestan with hydroxy substituents at positions 3 and 9.
CYCLOFENIL
DIARYLPROPIONITRILE
DIENOGEST
DIETHYLSTILBESTROL DIPHOSPHATE
DIETHYLSTILBESTROL DIPROPIONATE
ELACESTRANT HYDROCHLORIDE
ERD-308
ESTERIFIED ESTROGENS
ESTETROL
ESTRADIOL ACETATE
ESTROGEN
ESTROGENS, CONJUGATED
ESTROGENS, CONJUGATED SYNTHETIC A
ESTROGENS, ESTERIFIED
ESTROPIPATE
ETHANOLAMINE
ETHYLENEDIAMINE
FISPEMIFENE
FOSFESTROL
GIREDESTRANT
GLYCITEIN A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.
GOSERELIN
GSK5182
GTX-758
H3B-6545
HORMONE THERAPY AGENT
ICARITIN
IODINE
LASOFOXIFENE
LASOFOXIFENE TARTRATE
LSZ102
LY2245461
MEDROXYPROGESTERONE A 3-oxo Delta(4)-steroid that is pregn-4-ene-3,20-dione substituted by an alpha-hydroxy group at position 17 and a methyl group at position 6.
MEGESTROL A 3-oxo Delta(4)-steroid that is pregna-4,6-diene-3,20-dione substituted by a hydroxy group at position 17.
METHIOCARB A carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of methylcarbamic acid.
METHYL-PIPERIDINO-PYRAZOLE
METHYLISOTHIOCYANATE
MK-6913
N-PROPYL BROMIDE
NOMEGESTROL ACETATE
OCHRATOXIN A A phenylalanine derivative resulting from the formal condensation of the amino group of L-phenylalanine with the carboxy group of (3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxylic acid. It is among the most widely occurring food-contaminating mycotoxins, produced by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium verrucosum.
PALMITATE
PHENYLALANINE
PRINABEREL
PROMESTRIENE
PUERARIN An isoflavonoid that has formula C21H20O9.
R,R-THC
RALOXIFEN
SELECTIVE ESTROGEN RECEPTOR COVALENT ANTAGONIST H3B-6545
SELECTIVE ESTROGEN RECEPTOR DEGRADER AZD9496
SELECTIVE ESTROGEN RECEPTOR MODULATOR CC-8490
SELECTIVE ESTROGEN RECEPTOR MODULATOR TAS-108
SIVIFENE
SULFENTRAZONE
SYNTHETIC CONJUGATED ESTROGENS, A
SYNTHETIC CONJUGATED ESTROGENS, B
TAS-108
TRIADIMEFON A racemate comprising equal amounts of (R)- and (S)-triadimefon. A fungicide used to control powdery mildew, rusts and other infections in many crops.
TTC-352
VINTAFOLIDE
WAY200070
(S)-LIQUIRITIGENIN
AUS-131
CHEMBL:CHEMBL2332580
ERTEBEREL
FERB 033
MENERBA
MF101
PHTPP
1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE
DEXAMETHASONE PALMITATE
PREGNENOLONE
DY131
GSK4716
TK216
(R)-EDELFOSINE
BITHIONOLOXIDE
CHEMBL:CHEMBL582099
CHEMBL:CHEMBL591363
CHEMBL:CHEMBL591876
CHEMBL:CHEMBL592068
CHEMBL:CHEMBL95704
HEXAMETHYL PARAROSANILINE
SOLYPERTINE TARTRATE
GSK343
TULMIMETOSTAT
VALEMETOSTAT
ZEPRUMETOSTAT
CHEMBL:CHEMBL4545488
COMPOUND 15A [PMID: 36642961]
CPI-1205
EBI-2511
EI1
EPZ005687
EPZ011989
JQEZ5
MEVROMETOSTAT
SKLB-03220
TAZEMETOSTAT HYDROBROMIDE
UNC1999
2-O, 3-O DESULFATED HEPARIN
ANDEXANET ALFA
ANTITHROMBIN ALFA
BAY 3389934
BEMIPARIN
BETRIXABAN
CERTOPARIN SODIUM
COAGULATION FACTOR IX
COAGULATION FACTOR VIIA
COAGULATION FACTOR X HUMAN
COAGULATION FACTOR X, HUMAN
DANAPAROID
DAREXABAN
DX-9065A
EDOXABAN TOSYLATE
EMICIZUMAB
EP-217609
ERIBAXABAN
FACTOR IX
FACTOR VIII
FONDAPARINUX A synthetic pentasaccharide which, apart from the O-methyl group at the reducing end of the molecule, consists of monomeric sugar units which are identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparin and heparan sulfate.
GW-813893
IDRABIOTAPARINUX SODIUM
IDRAPARINUX
IDRAPARINUX SODIUM
JTV-803
LETAXABAN
LY-517717
MANGIFERIN HEPTASULFATE
MELAGATRAN A member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group.
NADROPARIN CALCIUM
NONACOG ALFA
OTAMIXABAN
PROTHROMBIN COMPLEX CONCENTRATE
SEMULOPARIN
SR-123781A
SSR-126517E
TANOGITRAN
THROMBIN Thrombin is a trypsin-like serine protease protein that in humans is encoded by the F2 gene.[2][3] Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.
TINZAPARIN SODIUM
ZIFAXABAN
ABELACIMAB
ALPHA-KETOTHIAZOLE ANALOGUE 36
EP-7041
FESOMERSEN
FXIA INHIBITOR 3F
GRUTICIBART
OSOCIMAB
SULFATED PENTAGALLOYLGLUCOSIDE
ANTI-FXII NANOBODY N4-38
BISMUTH SUBGALLATE
CHEMBL:CHEMBL935
GARADACIMAB
METHYL 5-[(4-TERT-BUTYLBENZOYL)AMINO]-2H-1,2,4-TRIAZOLE-3-CARBOXYLATE
FACTOR XIII, HUMAN
ANISINDIONE
APRAMIDE A
AR-H067637
ARGATROBAN An alpha-N-substituted L-arginine that has formula C23H36N6O5S.
ASPIRIN TRELAMINE
ATECEGATRAN METOXIL
AZ12971554
AZD-8165
BIVALIRUDIN
CHEMBL:CHEMBL586628
CYANIDIN
CYANIN
DABIGATRAN ETEXILATE MESYLATE
DESIRUDIN
DPOC-4088
DUP-714
ENOXAPARIN SODIUM
FLOVAGATRAN
HIRUDIN
ICHORCUMAB
LUSUTROMBOPAG
ODIPARCIL
PEGMUSIRUDIN
PROTHROMBIN
WX-UK1
XIMELAGATRAN A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted to the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage.
ATOPAXAR
DALTEPARIN
F16357
PZ-128
RUSALATIDE
RWJ-56110
SCH-79797
TFLLR-NH2
VORAPAXAR A carbamate ester that is the ethyl ester of [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethynyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamic acid. A protease-activated receptor-1 antagonist used (as its sulfate salt) for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease. It has been shown to reduce the rate of a combined endpoint of cardiovascular death, MI, stroke and urgent coronary revascularisation.
VORAPAXAR SULFATE
[3H]HATRAP
2-FUROYL-LIGRLO-AMIDE
2-FUROYL-LIGRL[N-(ALEXA FLUOR 594)-O]-NH2
2-FUROYL-LIGRL[N[3H]PROPIONYL]-O-NH2
AC-55541
AC-98170
AC264613
AY77
AZ2429
AZ3451
AZ7188
AZ8838
C391
GB110
GB88
I-191
I-287
ISOX-CHA-CHG-ALA-ARG-DPR(4FB)-NH2
ISOX-CHA-CHG-ARK(SULFO-CY5)-NH2
P2PAL18S
SLIGKV-NH2
SLIGRL-NH2
TRANS-CINNAMOYL-LIGRLO [N-[3H]PROPIONYL]-NH2
[3H]2-FUROYL-LIGRL-NH2
AYPGKF-NH2
BMS-986120
BMS-986141
GYPGKF-NH2
GYPGQV-NH2
ML354
P4PAL-10
RAG8
UDM-001651
YD-3
ANPOCOGIN
ANTI-TF MONOCLONAL ANTIBODY ALT-836
MORAB-066
TISOTUMAB VEDOTIN
COAGULATION FACTOR VII HUMAN
COAGULATION FACTOR VIIA (RECOMBINANT)-JNCW
COMPOUND 1 [PMID: 16650987]
COMPOUND 11 [PMID: 16413183]
EPTACOG ALFA (ACTIVATED)
EPTACOG ALFA PEGOL (ACTIVATED)
EPTACOG BETA (ACTIVATED)
MARZEPTACOG ALFA (ACTIVATED)
PCI-27483
VATREPTACOG ALFA (ACTIVATED)
ANTIHEMOPHILIC FACTOR (RECOMBINANT) PEGYLATED-EXEI
ANTIHEMOPHILIC FACTOR, PEGYLATED (MW 20000) HUMAN SEQUENCE RECOMBINANT
DAMOCTOCOG ALFA PEGOL
EFANESOCTOCOG ALFA
EFMOROCTOCOG ALFA
GIROCTOCOGENE FITELPARVOVEC
LONOCTOCOG ALFA
MOROCTOCOG ALFA
OCTOCOG ALFA
OMFILOCTOCOG ALFA
RECOMBINANT FACTOR VIIA
SIMOCTOCOG ALFA
SORBITOL
SUSOCTOCOG ALFA
TB-402
TUROCTOCOG ALFA
TUROCTOCOG ALFA PEGOL
ALBUTREPENONACOG ALFA
COAGULATION FACTOR IX (RECOMBINANT), GLYCOPEGYLATED
COAGULATION FACTOR IX HUMAN
COAGULATION FACTOR IX RECOMBINANT HUMAN
COMPOUND 57 [PMID: 20121197]
EFTRENONACOG ALFA
ETRANACOGENE DEZAPARVOVEC
FIDANACOGENE ELAPARVOVEC
LEVOTHYROXINE SODIUM
NONACOG BETA PEGOL
PEGNIVACOGIN
TRENONACOG ALFA
TTP889
VALOCTOCOGENE ROXAPARVOVEC
(R)-ARN2508
(S)-ARN2508
ASP8477
BIA 10-2474
BIA 10-2639
CAY10499
CHEMBL:CHEMBL1915783
CHEMBL:CHEMBL367966
EXAMPLE 13 [WO2009109743]
JNJ-42165279
JNJ40355003
MM-433593
OL135
PF-04457845
PF3845
SA-57
URB597
LY2077855
COMPOUND 13 [PMID: 17502136]
HM50316
AZD2389
BIBH 1
F19 131I
SIBROTUZUMAB
SIMLUKAFUSP ALFA
ADENOVIRUS 5-CD40 LIGAND
ARG098
ASUNERCEPT
EDELFOSINE A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
FAS LIGAND
OFRANERGENE OBADENOVEC
SILICON PHTHALOCYANINE 4
CERULENIN An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.
CHEMBL:CHEMBL577862
CHEMBL:CHEMBL578883
CHEMBL:CHEMBL604664
DENIFANSTAT
GSK2194069
GT 389-255
LORGLUMIDE SODIUM
PRETOMANID
DORLIMOMAB ARITOX
ELX-02
MT-3724
MANAGLINAT DIALANETIL
MB-07803
BELINOSTAT A hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
CRENIGACESTAT
HDAC INHIBITOR REC-2282
JQ1
MRK-003
BSAB (CD89-CD20)
BENZYLPENICILLOYL POLYLYSINE Poly-L-lysine (n > 40) in which 50-70% of the epsilon-amino groups are substituted with benzylpenicilloyl groups. It is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy.
IGE HEAVY CHAIN
OMALIZUMAB
R112
GOMILIXIMAB
LUMILIXIMAB
BISPECIFIC ANTIBODY MDX447
VALZIFLOCEPT
AFM-13
AFM13
BEMARITUZUMAB
CA19-9 ANTIGEN
GMA-161
MAFOSFAMIDE
MATRIX METALLOPROTEINASE INHIBITOR
PENICILLIN ANTIBIOTIC
TESMILIFENE HYDROCHLORIDE
BATOCLIMAB
DX-2507
ORILANOLIMAB
ZILTIVEKIMAB
RG-7598
1-ALLYL-2-[3-(ISOPROPYLAMINO)PROPOXY]-9H-CARBAZOLE
1-ALLYL-2-[3-(ISOPROPYLAMINO)PROPOXY]-9H-XANTHEN-9-ONE
BPH-830
COMPOUND 1 [OVERHAND ET AL., 1997]
COMPOUND 13 [PMID: 19456099]
COMPOUND 14 [PMID: 19191557]
COMPOUND 15 [PMID: 19456099]
COMPOUND 15A [PMID: 22464687]
COMPOUND 19 [PMID: 19191557]
COMPOUND 1C [BROWN ET AL., 1997]
COMPOUND 21 [PMID: 19191557]
COMPOUND 3 [PMID: 19191557]
COMPOUND 32 [PMID: 19191557]
COMPOUND 35 [PMID: 19191557]
COMPOUND 3A [PMID: 12238936]
COMPOUND 3F [PMID: 12238936]
COMPOUND 4G [PMID: 17709461]
COMPOUND 4Q [PMID: 7650673]
COMPOUND 6 [PMID: 7629799]
COMPOUND 8 [PMID: 19191557]
E5700
J-104118
J-104123
LAPAQUISTAT ACETATE
NB-598
SQ-109
YM-75440
ZARAGOZIC ACID A A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase.
COMPOUND 2 [PMID: 18295483]
COMPOUND 31 [PMID: 17963374]
COMPOUND 5E [PMID: 17975902]
DIPHOSPHORIC ACID An acyclic phosphorus acid anhydride obtained by condensation of two molecules of phosphoric acid.
GERANYL BIPHOSPHONATE
IBANDRONATE
IBANDRONATE SODIUM
INCADRONIC ACID
ISOPENTENYL PYROPHOSPHATE
MINODRONIC ACID
NE10575
NE10790
NE11808
NE21650
NE58018
NE58027
NE58043
NE58062
NE97220
NERIDRONIC ACID
PIRIDRONIC ACID
RIBOPRINE
RISEDRONATE SODIUM
ZOLEDRONIC ACID
CELIPROLOL HYDROCHLORIDE
DABELOTINE
GUANADREL SULFATE A sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
OXILOFRINE
METHYL AMINOLEVULINATE
AMENTOFLAVONE A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring. A natural product found particularly in Ginkgo biloba and Hypericum perforatum.
AMINACRINE HYDROCHLORIDE
CCG-63802
CEFSULODIN SODIUM
CHARTREUSIN
CHEMBL:CHEMBL1092508
CHEMBL:CHEMBL1453126
CHEMBL:CHEMBL1509103
CHEMBL:CHEMBL151146
CHEMBL:CHEMBL1528359
CHEMBL:CHEMBL1622802
CHEMBL:CHEMBL1726814
CHEMBL:CHEMBL483206
CHEMBL:CHEMBL486706
CHEMBL:CHEMBL494668
CHEMBL:CHEMBL521171
CHEMBL:CHEMBL525103
CHEMBL:CHEMBL526763
CHEMBL:CHEMBL528724
CHEMBL:CHEMBL532504
CHEMBL:CHEMBL533082
CHEMBL:CHEMBL578719
CHEMBL:CHEMBL582503
CHEMBL:CHEMBL589915
CHEMBL:CHEMBL592598
CHEMBL:CHEMBL602127
CHEMBL:CHEMBL68096
DEMECLOCYCLINE Tetracycline which lacks the methyl substituent at position 7 and in which the hydrogen para- to the phenolic hydroxy group is substituted by chlorine. Like tetracycline, it is an antibiotic, but being excreted more slowly, effective blood levels are maintained for longer. It is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
DITHIAZANINE
FAGARONINE
FURAMIDINE
GW305074X
INDOCYANINE GREEN ACID FORM
PAMOIC ACID A dicarboxylic acid that has formula C23H16O6.
PHENYLSTIBONIC ACID
PINAFIDE
SRT1720
DS21360717
AMG-837
CHEMBL:CHEMBL2152070
CHEMBL:CHEMBL277845
CHEMBL:CHEMBL6931
COMPOUND 4 [PMID: 27074625]
COMPOUND B [PMID:18477808]
DIDODECANOYLPHLOROGLUCINOL
FASIGLIFAM
FASIGLIFAM HEMIHYDRATE
GW1100
GW9508
HWL-088
LY-2881835
LY2881835
MEDICA 16
MYRISTIC ACID A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
OLEIC ACID An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
SETOGEPRAM
TUG-424
TUG-770
TUG-905
ZYDG2
(S)-4-CMTB
1-METHYLCYCLOPROPANECARBOXYLIC ACID
ACETATE
AMG7703
BUTYRIC ACID A four-carbon straight-chain saturated fatty acid.
CATPB
CPTB
GLPG-0974
GLPG0974
ISOBUTYRIC ACID A branched fatty acid comprising propanoic acid carrying a methyl branch at C-2.
PROPIONIC ACID
TRANS-2-METHYLCROTONIC ACID
TUG-1375
TUG-2304
VALERIC ACID A straight-chain saturated fatty acid containing five carbon atoms.
FHQC
COMPOUND A [PMID 24997608]
GRIFOLIC ACID
GRIFOLIC ACID METHYL ETHER
NCG21
TUG-1197
ABCIXIMAB
ALFIMEPRASE
ALTEPLASE
ANCROD
EPTIFIBATIDE
FIBRINOGEN, HUMAN
PLASMIN
PLASMINOGEN
RETEPLASE
TIROFIBAN
BICIROMAB BRALLOBARBITAL
ALDAFERMIN
FAZPILODEMAB
MUPARFOSTAT
PEGBELFERMIN
SPRIFERMIN
FGFR4 INHIBITOR H3B-6527
FISOGATINIB
FAMOTIDINE A guanidine that has formula C8H15N7O2S3.
PYRAZOLE COMPOUND
REBAMIPIDE
RECOMBINANT LYMPHOKINE
RECOMBINANT THYROID-STIMULATING HORMONE
SHARK CARTILAGE EXTRACT AE-941
SQUALAMINE
SUCRALFATE
TSP-1 MIMETIC ABT-510
MORACIN M
BUROSUMAB
LUCITANIB
ALFERMINOGENE TADENOVEC
3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE
BLU-9931
BRIVANIB ALANINATE
CATEQUENTINIB
CHEMBL:CHEMBL2216830
COMPOUND 29 [PMID: 36356320]
COMPOUND 7R [PMID: 26080733]
COMPOUND 8H [PMID: 22765894]
CP-459632
DABOGRATINIB
DERAZANTINIB
FANREGRATINIB
FGF RECEPTOR ANTAGONIST HGS1036
FGF-1
FGF-21
FGFR INHIBITOR CPL304110
FGFR INHIBITOR DEBIO 1347
FP-1039
GUNAGRATINIB
HMPL-453
INFIGRATINIB
INFIGRATINIB PHOSPHATE
LY-2874455
LY2874455
MK-2461
ODM-203
PALIFERMIN
PEGOZAFERMIN
PEMIGATINIB
PHA-665752
PRN1371
RATANGRATINIB HYDROCHLORIDE
RISIMTINIB
SU-11652
SU-14813
SURUFATINIB
TASURGRATINIB
TOCERANIB
TOPICAL POTASSIUM DOBESILATE
TRAFERMIN
TYRA-200
VEPUGRATINIB
VISTUSERTIB
XL-999
ZOLIGRATINIB
ZOTATIFIN
AEE-788
ALOFANIB
APRUTUMAB
APRUTUMAB IXADOTIN
CETRELIMAB
FGFR2 INHIBITOR 3HP-2827
KIN-3248
LIRAFUGRATINIB
RESIGRATINIB
S-49076
ANLOTINIB
ASP5878
COMPOUND 1D [PMID: 21493067]
DOVITINIB LACTATE
QUISINOSTAT
SINTILIMAB
SSR128129E
TYROSINE KINASE INHIBITOR SU5402
VOFATAMAB
COMPOUND A34 [PMID: 35635004]
FGF-19
FGF401
FGFR INHIBITOR ASP5878
FGFR4 ANTAGONIST INCB062079
IONIS-FGFR4RX
IRPAGRATINIB
RECOMBINANT FIBROBLAST GROWTH FACTOR 6
ROBLITINIB
FRUCTOSE A ketohexose that is an isomer of glucose.
GPI-1485
OLOCROLIMUS
PIMECROLIMUS
RIMIDUCID
SLF
TACROLIMUS
ZOTAROLIMUS
COMPOUND 19B [PMID: 37058391]
SAFIT1
SAFIT2
DM-CHX
GPI-1046
SIMUFILAM
4SC-203
ABICIPAR PEGOL
AG-13958
AGN-211745
CEP-5214
CEP-7055
EW-A-401
FAMITINIB
FRUQUINTINIB
ICRUCUMAB
L-21649
LENVATINIB MESYLATE
MOTESANIB A pyridinecarboxamide that has formula C22H23N5O.
PEGPLERANIB SODIUM
SU-014813
TABERMINOGENE VADENOVEC
TAK-593
TELATINIB
TELBERMIN
TIVOZANIB HYDROCHLORIDE
VEGF RECEPTOR TYROSINE KINASE INHIBITOR III
VEGFA vascular endothelial growth factor A|This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
VEGFB vascular endothelial growth factor B|This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]
VEGFRECINE
X-82
XL-820
XL820
AGI-5198
AGL 2043
AGS62P1
AKN-028
ALTIRATINIB
AMG553
AMUVATINIB
ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049
AS-602868
BAY-985
C-1311
CDX-301
CEP-2563 DIHYDROCHLORIDE
CHEMBL:CHEMBL3417704
CLIFUTINIB
CM-082
COMPOUND 13AC [PMID: 33256400]
COMPOUND 18E [PMID: 31670517]
COMPOUND 34F [PMID: 37535845]
COMPOUND 5E [PMID: 28580438]
COMPOUND 7D [PMID: 29672049]
DENFIVONTINIB
DENFIVONTINIB HYDROCHLORIDE
DOMATINOSTAT
ENASIDENIB
FEDRATINIB HYDROCHLORIDE
FF-10101
FIMEPINOSTAT
FLONOLTINIB MALEATE
FLT-3 INHIBITOR
FLT-3 INHIBITOR II
FLT-3 INHIBITOR III
FLT3 INHIBITOR BMF-500
FLT3 INHIBITOR FF-10101 SUCCINATE
FLT3 TYROSINE KINASE INHIBITOR TTT-3002
FLT3/ABL/AURORA KINASE INHIBITOR KW-2449
FLT3/CDK4/6 INHIBITOR FLX925
FLYSYN
FMS-RELATED TYROSINE KINASE 3 LIGAND
FN-1501
GLASDEGIB
HSP90 INHIBITOR LAM-003
IMC-EB10
LWY713
MAX-40279
MELK INHIBITOR OTS167
MIVAVOTINIB
MRX-2843
NUVISERTIB
ONVANSERTIB
PATIDEGIB
PHI-101
QUIZARTINIB DIHYDROCHLORIDE
REVUMENIB
SELINEXOR
SGI-1776
SHP2 INHIBITOR ERAS-601
SONIDEGIB
TAFETINIB
TIRBANIBULIN
TTT-3002
TUSPETINIB
TYRPHOSTIN AG 1295
TYRPHOSTIN AG 1296
VS-5584
CHLORPYRAMIN HYDROCHLORIDE
COMPOUND 25C [PMID: 36649216]
COMPOUND 38K [PMID: 34351741]
IMC-3C5
VEGFC vascular endothelial growth factor C|The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]
VEGFD
VEGFE
AS-1409
AS1409
DAROMUN
L19IL2
L19SIP 131I
L19TNFA
MU-BC-1
ONFEKAFUSP ALFA
RADRETUMAB
CP-609,754
GGTI-2418
BMS-214662
DARLIFARNIB
FTI 276
L-739,750
LB42908
APVO-414
AUTOLOGOUS PSMA-4SCAR-EXPRESSING T-CELLS 4SCAR-PSMA
CAPROMAB
CAPROMAB PENDETIDE
COMPOUND 8D [PMID: 15027864]
CYT-500 177LU
HUJ591 111IN
HUJ591 177LU
J591 177LU
LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN
LUTETIUM LU-177 VIPIVOTIDE TETRAXETAN
MDX-070
MLN-2704
MLN-591RL
TECHNETIUM TC 99M TROFOLASTAT
VIPIVOTIDE TETRAXETAN
YTTRIUM Y 90 CAPROMAB PENDETIDE
EPOFOLATE
FARLETUZUMAB
FOLATE RECEPTOR-TARGETED VINCA ALKALOID EC0489
LOMETREXOL
MIRVETUXIMAB
MIRVETUXIMAB SORAVTANSINE
RINATABART SESUTECAN
TETRAHYDROFOLIC ACID A group of heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with one or more L-glutamic acid units.
MAGNESIUM SULFATE A magnesium salt having sulfate as the counterion.
PROTEIN KINASE A INHIBITOR
RECOMBINANT INTERLEUKIN-1-BETA
SYRINGARESINOL
3570-0208 [PMID:19807662]
AG-09/1
AG-11/03
AG-14
ANNEXIN I-(2-26)
AZ2158
BMS-986235
BVT173187
CHEMBL:CHEMBL1290365
COMPOUND 17B [PMID: 19639995]
COMPOUND R-(-)-5F [PMID: 22607879]
CYCLOSPORIN H
DEOXYCHOLIC ACID A dihydroxy-5beta-cholanic acid that has formula C24H40O4.
DIAMIDE 7
FMET-ILE-PHE-LEU
FMET-ILE-VAL-ILE-LEU
FMET-ILE-VAL-THR-LEU-PHE
FMET-LEU-PHE
FMET-LEU-PHE-ILE-ILE
FMET-MET-TRP-LEU-LEU
FMET-MET-TYR-ALA-LEU-PHE
GG-2P20
GROUP E 1682-2106 [PMID:16118363]
I-BOC-MET-LEU-PHE
MET-MET-TRP-LEU-LEU
METHIONINE BENZIMIDAZOLE 6
MITOCHONDRIAL PEPTDE FMMYALF
MITOCHONDRIAL PEPTIDE FMFADRW
PENICILLIN G POTASSIUM
SPINORPHIN
T-0080
T-BOC-FLFLF
T-BOC-MET-LEU-PHE
T20(DP178)
WKYMVM
[125I]CATHEPSIN G (HUMAN)
[125I]CHIPS
[3H]FMET-LEU-PHE
1R-11
ACT-389949
AG-26
AMYLOID &BETA;
ANNEXIN I
ASPIRIN TRIGGERED LIPOXIN A4
ASPIRIN-TRIGGERED RESOLVIN D1
ATLA2
BMS-986331
CGEN-855A
CHEMBL:CHEMBL1290139
COMPOUND 1754-31 [PMID: 23788657]
COMPOUND 43 [PMID: 21173551]
F PEPTIDE
FPRL1-INHIBITOR PROTEIN
HP(2-20)
HUMANIN
ISOPROPYLUREIDO-FLFLF
LXA4
MHC BINDING PEPTIDE
MMK-1
N36
PBP10
PRP106-126
PSM&ALPHA;3
QUIN-C1
QUIN-C7
RESOLVIN D1 A very long-chain fatty acid that has formula C22H32O5.
RESOLVIN D3
ROPOCAMPTIDE
RVD1-ME
SCK&BETA;8-1
SERUM AMYLOID A
SHAAGTIDE
T21/DP107
UPAR FRAGMENT
V3 PEPTIDE
WRWWWW
[125I-TYR]AC2-26
[3H]LXA4
F2L
F2L-[125I]TYR
NP-G2-044
FOLLICLE STIMULATING HORMONE
CHORIONIC GONADOTROPIN
CORIFOLLITROPIN ALFA
FOLLITROPIN
FOLLITROPIN ALFA
FOLLITROPIN BETA
FOLLITROPIN DELTA
FSH DEGLYCOSYLATED &ALPHA;/&BETA;
THYROTROPIN ALFA
UROFOLLITROPIN
[125I]FSH (HUMAN)
ALPHA-ADRENERGIC AGONIST
ANTICOAGULANT AGENT
RECOMBINANT HEREGULIN
FERRITARG P
FURIN INHIBITOR PEPTIDE
MI-1148
PEPTIDE 18 [PMID: 24350995]
PHENYLACETYL-ARG-VAL-ARG-4-AMIDINOBENZYLAMIDE
HU3S193
CHEMBL:CHEMBL464249
CHEMBL:CHEMBL593726
FZM1
FZM1.8
NORRIN
SAG1.3
WNT-3A
WNT-4
WNT-5A
F7H
FZ7-21
SRI37892
IPAFRICEPT
ACETAMINOPHEN/TRAMADOL
ARTICAINE HYDROCHLORIDE
CARBASALATE CALCIUM
EPIANDROSTERONE A 3beta-hydroxy steroid that is (5alpha)-androstane substituted by a beta-hydroxy group at position 3 and an oxo group at position 17.
FURAZOLIDONE
METABUTETHAMINE
MOXIFLOXACIN A quinolone that consits of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid bearing a cyclopropyl substituent at position 1, a fluoro substitiuent at position 6, a (4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl group at position 7 and a methoxy substituent at position 8. A member of the fluoroquinolone class of antibacterial agents.
PAMAQUINE
PEGLOTICASE
PHENAZOPYRIDINE
POTASSIUM CHLORIDE A metal chloride salt with a K(+) counterion.
PRILOCAINE An amide-type local anaesthetic in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond.
SITAMAQUINE
SODIUM ASCORBATE
SODIUM NITRATE
SODIUM SULFATE ANHYDROUS
SULFACETAMIDE
SULFADIAZINE A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
SULFAMETHAZINE
SULFAMETHOXAZOLE An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
SULFANILAMIDE A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position.
TAFENOQUINE
TETRACAINE A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
TRIMETHOPRIM-SULFAMETHOXAZOLE
5-HYDROXYINDOLE
ACRIDONE
ALPHA GLUCOSIDASE
AVALGLUCOSIDASE ALFA
CASTANOSPERMINE
CELGOSIVIR
CHEMBL:CHEMBL12019
CHEMBL:CHEMBL1256665
CHEMBL:CHEMBL1422873
CHEMBL:CHEMBL267160
CHEMBL:CHEMBL585828
CHEMBL:CHEMBL604100
DUVOGLUSTAT
DUVOGLUSTAT HYDROCHLORIDE
HYDROXYTYROSOL
IMINOSTILBENE
MIGALASTAT
MIGLITOL
NODAKENIN
PROTOCATECHUIC ACID
REVEGLUCOSIDASE ALFA
SALACINOL
TERAZOSIN HYDROCHLORIDE HYDRATE
VOGLIBOSE
ARBACLOFEN PLACARBIL
CALCIUM OXYBATE
CGP 36742
CGP 47656
LESOGABERAN
MAGNESIUM OXYBATE
POTASSIUM OXYBATE
PROGABIDE
OT-551
&ALPHA;3IA
&ALPHA;5IA
ABP-700
ADINAZOLAM A triazolo[4,3-a][1,4]benzodiazepine having a dimethylaminomethyl group at the 1-position, a phenyl group at the 6-position and a chloro substituent at the 8-position.
ADIPIPLON
AMOBARBITAL
BARBITAL
BARBITURATE
BICUCULLINE Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
BRETAZENIL
BREXANOLONE
BUTABARBITAL SODIUM
CENOBAMATE
CGS8216
CHEMBL:CHEMBL2170369
CHLORDIAZEPOXIDE HYDROCHLORIDE
CINOLAZEPAM A 1,4-benzodiazepinone compound having a 2-cyanoethyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-fluorophenyl group at the 5-position and a chloro substituent at the 7-position, it has general properties similar to those of diazepam and has been used for the short-term management of sleep disorders.
CIPEPOFOL
CLORAZEPATE
CLORAZEPATE DIPOTASSIUM
CLOTIAZEPAM
DARIGABAT
DMCM
ESZOPICLONE
ETHCHLORVYNOL
ETIFOXINE
EVT 201
FLUDIAZEPAM A 1,4-benzodiazepinone that has formula C16H12ClFN2O.
FLURAZEPAM
FLURAZEPAM HYDROCHLORIDE
GABOXADOL
HALAZEPAM
IMEPITOIN
INDIPLON
ISOGUVACINE A tetrahydropyridine that has formula C6H9NO2.
ISONIPECOTIC ACID
ISOPIMARIC ACID
L838417
LOREDIPLON
MEPROBAMATE
METHAQUALONE
METHAQUALONE HYDROCHLORIDE
METHOHEXITAL A barbiturate, the structure of which is that of barbituric acid substituted at N-1 by a methyl group and at C-5 by allyl and 1-methylpent-2-ynyl groups.
METHOHEXITAL SODIUM
METHYPRYLON
MRK016
NITRAZEPAM
OCINAPLON
PADSEVONIL
PAGOCLONE
PICROTOXIN
PIPERIDINE-4-SULPHONIC ACID
QUAZEPAM
REMIMAZOLAM BESYLATE
RESEQUINIL
RO15-4513
RO4938581
SANDARACOPIMARIC ACID
SECOBARBITAL SODIUM
TBPS
TETRAHYDRODEOXYCORTICOSTERONE
TETRAZEPAM
THIAMYLAL A member of the class of barbiturates that is 2-thioxodihydropyrimidine-4,6(1H,5H)-dione substituted by a pentan-2-yl and prop-2-en-1-yl group at position 5.
THIOCOLCHICOSIDE
TP003
TPA023
TRICLOFOS SODIUM
ZALEPLON A pyrazolo[1,5-a]pyrimidine having a nitrile group at position 3 and a 3-(N-ethylacetamido)phenyl substituent at the 7-position.
ZK-93423
ZK93423
ZK93426
ZOPICLONE
ZURANOLONE
[18F]FLUOROETHYLFLUMAZENIL
[35S]TBPS
[3H]AZIETOMIDATE
[3H]CGS8216
[3H]MUSCIMOL
AZD6280
AZD7325
ETAZOLATE
ALOGABAT
BASMISANIL
CHEMBL:CHEMBL1077391
COMPOUND 20 [PMID: 35584373]
L655708
ONO-8590580
RY024
[3H]L655708
LAU159
LAU463
PZ-II-029
FOSPROPOFOL
DS2
AZD-3043
BENTAZEPAM
CHLORMETHIAZOLE
MEBUTAMATE
ORG-25435
SARIPIDEM
STIRIPENTOL
(&PLUSMN;)-CIS-2-CAMP
5-ME-IAA
AZA-THIP
CIS-3-ACPBPA
TPMPA
TRANS-3-ACPBPA
S-ALLYLGLYCINE
BRIVUDINE PHOSPHORAMIDATE
PYRANTEL PAMOATE An organic molecular entity that has formula C23H16O6.C11H14N2S.
ELOSULFASE ALFA
2,3-DIHYDRO-1,4-DITHIIN-1,1,4,4-TETROXIDE
C7 complement component 7|C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008]
DITHIIPIN-1,1,4,4-TETROXIDE ANALOGUE 7
GAL-(K)4
GAL-B2
GAL-B2-C10
GAL-B2-C12
GAL-B2-C14
GAL-B2-C18
GAL-B2-C8
GAL-B2-DPEG24
GAL-B2-MPEG4
GAL-B5
GALANIN
GALANIN(1-11)
GALANIN(1-15)
GALANIN(1-16) (RAT/MOUSE/PIG)
GALANIN(1-19) (HUMAN)
GALANIN(2-11)
GALANIN(2-29) (PIG)
GALANIN(2-29) (RAT/MOUSE)
GALANIN(2-30) (HUMAN)
GALANIN(3-29) (PIG)
GALANIN(3-29) (RAT/MOUSE)
GALANIN(7-29) (PIG)
GALANIN(D-TRP2) (PIG)
GALANIN-LIKE PEPTIDE
GALMIC
GALNON
GALP(1-32) (HUMAN)
GALP(3-32) (HUMAN)
GALR3ANT
J18 (GALANIN ANALOGUE)
J20 (GALANIN ANALOGUE)
M1145
M1151
M1152
M1153
M1160
M15
M242
M32
M35
M40
M617
M871
SCH 202596
[125I][TYR26]GALANIN (HUMAN)
[125I][TYR26]GALANIN (PIG)
[N-ME,DES-SAR]GAL-B2
[SAR1, D-ALA12]GALANIN(1-16)
GAL-R2-DPEG24
GALANIN(1-10)
GALANIN(1-12)
GALANIN(1-20) (HUMAN)
GALANIN(10-29) (PIG)
GALANIN(10-29) (RAT/MOUSE)
GALANIN(3-30) (HUMAN)
GALANIN(5-29) (RAT/MOUSE)
GALANIN(9-25) (RAT/MOUSE)
GALANIN(9-29) (RAT/MOUSE)
QU-SPX
SNAP 37889
SNAP 398299
SPEXIN-1
[125I]SPEXIN-1
CHEMBL:CHEMBL530291
ETILEFRINE
ALGENPANTUCEL-L
MIGLUSTAT
CHEMBL:CHEMBL502775
OMIGAPIL
PELITREXOL
GASTRIN IMMUNOTOXIN
CHEMBL:CHEMBL1684097
CHEMBL:CHEMBL1684098
CHEMBL:CHEMBL1684099
RIBAVIRIN MONOPHOSPHATE
HYDRONIDONE
AFEGOSTAT
AFEGOSTAT TARTRATE
AMBROXOL
APTIGANEL HYDROCHLORIDE
CHEMBL:CHEMBL1379900
CHEMBL:CHEMBL408500
CHEMBL:CHEMBL529939
CHEMBL:CHEMBL578928
CHEMBL:CHEMBL588327
CHEMBL:CHEMBL603154
CIRSIMARITIN
NCGC607
SULFANITRAN
TALIGLUCERASE ALFA
VELAGLUCERASE ALFA
DOCOSANOL
ERYTHRITYL TETRANITRATE
NITRIC OXIDE A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
PIRSIDOMINE
ALPHA-ADRENERGIC ANTAGONIST
COTADUTIDE
EFINOPEGDUTIDE
FRONIGLUTIDE
MECASERMIN
SAR425899
ADOMEGLIVANT
BAY27-9955
CROTEDUMAB
DASIGLUCAGON
DASIGLUCAGON HYDROCHLORIDE
GLUCAGON
GLUCAGON HYDROCHLORIDE
HGCGR ANTAGONIST
ISIS 325568
L-168,049
LGD-6972
MAZDUTIDE
MK-3577
NNC 92-1687
NNC0640
NNC1702
PEGAPAMODUTIDE
PF-06291874
REDIOCIDE A
RETATRUTIDE
RVT-1502
SURVODUTIDE
VOLAGIDEMAB
[125I]GLUCAGON (HUMAN, MOUSE, RAT)
GUANINE A 2-aminopurine carrying a 6-oxo substituent.
AZD1656
BMS-820132
DORZAGLIATIN
LY-2599506
LY-2608204
MK-0941
NERIGLIATIN
PF-04937319
PF-04991532
PIRAGLIATIN
RO-281675
7-METHYLXANTHINE An oxopurine that is xanthine in which the hydrogen attached to the nitrogen at position 7 is replaced by a methyl group. It is an intermediate metabolite in the synthesis of caffeine.
SULINDAC SULFIDE An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity.
LIATERMIN
LIRILUMAB
RECOMBINANT LUTEINIZING HORMONE
CHEMBL:CHEMBL1339206
CHEMBL:CHEMBL1713082
CHEMBL:CHEMBL585651
DIFFRACTAIC ACID
MEPAZINE ACETATE
PTEROSTILBENE A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'.
[125I]GDNF (RAT)
ARTEMIN
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein|This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]
GROWTH DIFFERENTIATION FACTOR 15
LY3463251
GGSTOP
(1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID
2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE
BPH-252
BPH-608
BPH-675
BPH-715
BPH-742
COMPOUND 12 [PMID: 12014956]
COMPOUND 14 [PMID: 18800762]
COMPOUND 16 [PMID: 18800762]
COMPOUND 19 [PMID: 18800762]
COMPOUND 47 [PMID: 18800762]
COMPOUND 51 [PMID: 18800762]
DIGERANYL BISPHOSPHONATE
GERANYLGERANYL DIPHOSPHATE A polyprenol diphosphate having geranylgeranyl as the polyprenyl component.
LAURYL ALCOHOL DIPHOSPHONIC ACID
[1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID
IPOMEANOL
ACP-001
ALBUSOMATROPIN
SEVIRUMAB
SOMATROGON
SOMAVARATAN
AOD9604
ARX201
GROWTH HORMONE 2
LONAPEGSOMATROPIN
PEGVISOMANT
SOMAPACITAN
SOMATREM
SOMATROPIN
BIM28011
JI-38
JMR-132
SERMORELIN
SERMORELIN ACETATE
SOMATORELIN
TESAMORELIN
TESAMORELIN ACETATE
MACIMORELIN
RELAMORELIN
ABBOTT 14C
ANAMORELIN
ANAMORELIN HYDROCHLORIDE
BIM 28163
CAPROMORELIN
CAPROMORELIN TARTRATE
EXAMORELIN
GHRELIN
GHRP-6
GSK1614343
HM01
IBUTAMOREN
IBUTAMOREN MESYLATE
IPAMORELIN
JMV3008
L-692,429
LENOMORELIN
LIVER ENRICHED ANTIMICROBIAL PEPTIDE 2
MACIMORELIN ACETATE
PF-05190457
PF-6870961
PRALMORELIN
SM-130,686
TZP-102
ULIMORELIN HYDROCHLORIDE
WFW-ISN-NH2
YIL781
[125I]TYR-ALA-HEXARELIN
[125I][HIS9]GHRELIN (HUMAN)
[125I][TYR4]GHRELIN (HUMAN)
[18F]AQ-12
[35S]IBUTAMOREN
[D-ARG1,D-PHE5,D-TRP7,9,LEU11]SUBSTANCE P
GASTRIC INHIBITORY POLYPEPTIDE
HUMAN GIP(1-30)NH2
HUMAN GIP(3-30)NH2
HUMAN GIP(3-42)NH2
HUMAN GIP(5-30)NH2
MARIDEBART CAFRAGLUTIDE
MGIPANT-1
TIRZEPATIDE
CARBENOXOLONE
OCTANOL A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of eight carbon atoms.
CHEMBL:CHEMBL1256390
MALTOSE
MIGALASTAT HYDROCHLORIDE
PEGUNIGALSIDASE ALFA
CHEMBL:CHEMBL1934585
CHEMBL:CHEMBL471694
CHEMBL:CHEMBL512307
COLUBRINIC ACID
CHEMBL:CHEMBL1701911
N-METHYLFORMAMIDE
6-AZAURIDINE
AMCINAFIDE
AMORFRUTIN A
AVEXITIDE
BETP
CHEMBL:CHEMBL127579
CHEMBL:CHEMBL1337519
CHEMBL:CHEMBL1422704
CHEMBL:CHEMBL1437888
CHEMBL:CHEMBL1439833
CHEMBL:CHEMBL1472891
CHEMBL:CHEMBL259615
CHEMBL:CHEMBL259805
CHEMBL:CHEMBL524376
CHEMBL:CHEMBL528791
CHEMBL:CHEMBL532452
CHEMBL:CHEMBL548286
CHEMBL:CHEMBL576809
CHEMBL:CHEMBL578515
CHEMBL:CHEMBL579956
CHEMBL:CHEMBL580207
CHEMBL:CHEMBL581865
CHEMBL:CHEMBL582286
CHEMBL:CHEMBL585444
CHEMBL:CHEMBL586078
CHEMBL:CHEMBL586163
CHEMBL:CHEMBL587564
CHEMBL:CHEMBL589909
CHEMBL:CHEMBL590427
CHEMBL:CHEMBL590919
CHEMBL:CHEMBL591598
CHEMBL:CHEMBL592118
CHEMBL:CHEMBL597244
CHEMBL:CHEMBL597251
CHEMBL:CHEMBL599100
CHEMBL:CHEMBL601351
CHEMBL:CHEMBL601400
CHEMBL:CHEMBL602012
CHEMBL:CHEMBL603130
CHEMBL:CHEMBL605708
CLANFENUR
COMPOUND 73 [PMID: 40167442]
CONVEGLIPRON
DA-302168S
DANUGLIPRON
DAPIGLUTIDE
DESIPRAMINE HYDROCHLORIDE
DIGITOXIGENIN A 5beta-cardenolide having hydroxy substituents at the 3beta- and 14beta-positions.
DIHYDROXANTHOHUMOL
ECNOGLUTIDE
EFPEGLENATIDE
ELECOGLIPRON
EXENATIDE
EXENDIN-3 A 39-membered polypeptide consisting of His, Ser, Asp, Gly, Thr, Phe, Thr, Ser, Asp, Leu, Ser, Lys, Gln, Met, Glu, Glu, Glu, Ala, Val, Arg, Leu, Phe, Ile, Glu, Trp, Leu, Lys, Asn, Gly, Gly, Pro, Ser, Ser, Gly, Ala, Pro, Pro, Pro and Ser-NH2 residues joined in sequence. It is isolated from venom of the Gila monster lizard Heloderma horridum.
GLP-1
GLUCAGON-LIKE PEPTIDE 1-(7-36) AMIDE
GLUCAGON-LIKE PEPTIDE 1-(7-37)
GLUTAZUMAB
INDOPROFEN A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
LIXISENATIDE
LOTIGLIPRON
LSN3318839
MAGNOLOL A biphenyl that has formula C18H18O2.
MOFEBUTAZONE
NAPERIGLIPRON
ORFORGLIPRON
PEGSEBRENATIDE
PEPTIDE 5 [PMID: 28562585]
PROPIONYLPROMAZINE HYDROCHLORIDE
PYROXAMINE MALEATE
SEMAGLUTIDE
STROPHANTHIDIN
T-0632
TASPOGLUTIDE
TH0318
TRICLABENDAZOLE
WB4-24
[125I]EXENDIN-(9-39)
[125I]GLP-1-(7-36)-AMIDE
[125I]GLP-1-(7-37) (HUMAN)
APRAGLUTIDE
ELSIGLUTIDE
FE 203799
GLEPAGLUTIDE
GLP-2 ANALOGUE 10
GLUCAGON-LIKE PEPTIDE 2
GLUCAGON-LIKE PEPTIDE 2-(3-33)
TEDUGLUTIDE A 33-membered polypeptide consisting of His, Gly, Asp, Gly, Ser, Phe, Ser, Asp, Glu, Met, Asn, Thr, Ile, Leu, Asp, Asn, Leu, Ala, Ala, Arg, Asp, Phe, Ile, Asn, Trp, Leu, Ile, Gln, Thr, Lys, Ile, Thr and Asp residues joined in sequence. A glucagon-like peptide-2 receptor agonist used for the treatment of short-bowel syndrome.
(12E,20Z,18S)-8-HYDROXYVARIABILIN
BILOBALIDE A terpenoid trilactone found in extracts of Ginkgo biloba.
CU2+
CYANOTRIPHENYLBORATE
D-SERINE The R-enantiomer of serine.
GINKGOLIDE B A diterpene lactone that has formula C20H24O10.
GINKGOLIDE X
PICROTIN A furopyran that has formula C15H18O7.
PICROTOXININ A furopyran that has formula C15H16O6.
PMBA
PREGNENOLONE SULPHATE
5,7-DICHLOROKYNURENIC ACID
ABIETIC ACID
AMPICILLIN SODIUM
CARBENICILLIN INDANYL
CEFAMANDOLE NAFATE FREE BASE
CEFATRIZINE
CEFMETAZOLE SODIUM
CEFQUINOME
CHEMBL:CHEMBL1527
CHEMBL:CHEMBL1707907
DICLOXACILLIN A penicillin that has formula C19H17Cl2N3O5S.
EVANS BLUE FREE ACID
GARENOXACIN
IPN60090
NAFCILLIN SODIUM
PIRENOXINE
PSOROMIC ACID
TELAGLENASTAT
CHF-5074
E-2212
E2012
OXYLANTHANUM CARBONATE
PF-06648671
BIW-8962
ACETOMENAPHTHONE
ACITRETIN
ANTAZOLINE HYDROCHLORIDE
AROMATICIN
BREFELDIN A A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
BROMHEXINE HYDROCHLORIDE
BROMOCICLEN
CHEMBL:CHEMBL1224755
CHEMBL:CHEMBL1256761
CHEMBL:CHEMBL1256911
CHEMBL:CHEMBL1317506
CHEMBL:CHEMBL1329349
CHEMBL:CHEMBL1366623
CHEMBL:CHEMBL1373255
CHEMBL:CHEMBL1374568
CHEMBL:CHEMBL1376851
CHEMBL:CHEMBL1388908
CHEMBL:CHEMBL1402376
CHEMBL:CHEMBL1415258
CHEMBL:CHEMBL1479114
CHEMBL:CHEMBL1496351
CHEMBL:CHEMBL156959
CHEMBL:CHEMBL1572415
CHEMBL:CHEMBL1588679
CHEMBL:CHEMBL1688556
CHEMBL:CHEMBL191611
CHEMBL:CHEMBL1939691
CHEMBL:CHEMBL1994034
CHEMBL:CHEMBL2094665
CHEMBL:CHEMBL2094833
CHEMBL:CHEMBL244023
CHEMBL:CHEMBL285157
CHEMBL:CHEMBL313154
CHEMBL:CHEMBL462430
CHEMBL:CHEMBL473721
CHEMBL:CHEMBL525098
CHEMBL:CHEMBL528492
CHEMBL:CHEMBL530499
CHEMBL:CHEMBL530788
CHEMBL:CHEMBL531451
CHEMBL:CHEMBL532363
CHEMBL:CHEMBL533388
CHEMBL:CHEMBL534047
CHEMBL:CHEMBL534244
CHEMBL:CHEMBL536008
CHEMBL:CHEMBL546475
CHEMBL:CHEMBL547245
CHEMBL:CHEMBL547313
CHEMBL:CHEMBL548017
CHEMBL:CHEMBL578929
CHEMBL:CHEMBL579420
CHEMBL:CHEMBL580955
CHEMBL:CHEMBL582276
CHEMBL:CHEMBL585462
CHEMBL:CHEMBL585654
CHEMBL:CHEMBL585795
CHEMBL:CHEMBL587433
CHEMBL:CHEMBL587728
CHEMBL:CHEMBL587801
CHEMBL:CHEMBL590184
CHEMBL:CHEMBL590665
CHEMBL:CHEMBL592600
CHEMBL:CHEMBL593211
CHEMBL:CHEMBL598679
CHEMBL:CHEMBL598695
CHEMBL:CHEMBL598885
CHEMBL:CHEMBL601180
CHEMBL:CHEMBL601358
CHEMBL:CHEMBL601768
CHEMBL:CHEMBL602126
CHEMBL:CHEMBL605747
CHEMBL:CHEMBL605753
CHEMBL:CHEMBL606532
CHEMBL:CHEMBL607140
CHLORACYZINE
CLIOXANIDE
CLOFENOXYDE
CUMINGIANOSIDE A
DEFEROXAMINE MESYLATE
DIACYLGLYCEROL KINASE INHIBITOR II
DIBUCAINE HYDROCHLORIDE
DIMETHYL SUCCINATE
DIPHENADIONE
DIPHYLLIN
EPOXYCYTOCHALASIN H
ETHYL NITRITE [SPIRIT]
ETRETINATE
EUPAROTIN ACETATE
FLAZALONE
FLUNARIZINE HYDROCHLORIDE
FOMOCAINE
GERONTOXANTHONE I
GITOXIGENIN
GITOXIN
GLYASPERIN D
GLYCYROL A coumestan that has formula C21H18O6.
GROSHEIMIN
HALETHAZOLE
IMIQUIMOD An imidazoquinoline that has formula C14H16N4.
LENPERONE
LIDAMIDINE HYDROCHLORIDE
LOFEPRAMINE
MELITRACEN
METHYL DEOXYCHOLATE
NIFURALDEZONE
NORARMEPAVINE
OCTRIZOLE
OTILONIUM
OXIBENDAZOLE
PIRIQUALONE
PIROCTONE
PROSULTIAMINE
SANTIN
SARPOGRELATE
SULBENTINE
THUNBERGINOL A
TRYPTANTHRIN
WOGONIN A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.
SOTRASTAURIN ACETATE
CHEMBL:CHEMBL1417470
CHEMBL:CHEMBL1456848
CHEMBL:CHEMBL1500913
CHEMBL:CHEMBL1506226
CHEMBL:CHEMBL1561747
CHEMBL:CHEMBL252417
CHEMBL:CHEMBL560296
ETOCARLIDE
TETRAETHYLAMMONIUM CHLORIDE
TRIACETIN
GNRH PHARMACCINE
ABARELIX A polypeptide compound composed of ten natural and non-natural amino acid resiudes in a linear sequence.
ACYLINE
ALARELIN
BAY1214784
BUSERELIN
CETRORELIX
CETRORELIX ACETATE
CMPD-1
CYCLORELIX
D-23487
D-24710
DEGARELIX
DEGARELIX ACETATE
DESLORELIN
DESLORELIN ACETATE
ELAGOLIX
ELAGOLIX SODIUM
FD-1
FERTIRELIN
GANIRELIX ACETATE
GNRH I
GNRH II
GNRH III
GONADORELIN ACETATE
GONADORELIN HYDROCHLORIDE
GOSERELIN ACETATE
HISTERELIN
HISTRELIN
HISTRELIN ACETATE
IN-3
ITURELIX
LEUPROLIDE MESYLATE
LINZAGOLIX
LINZAGOLIX CHOLINE
MERIGOLIX
NAFARELIN
NAFARELIN ACETATE
NBI-42902
ONVITRELIN UCALONTIDE
OPIGOLIX
OZARELIX
RELUGOLIX
SUFUGOLIX
T-98475
TEVERELIX
TRIPTORELIN
TRIPTORELIN PAMOATE
UCALOLICTIDE
WAY-207024
ZOPTARELIN DOXORUBICIN
[125I]CETRORELIX
[125I]GNRH I (HUMAN, MOUSE, RAT)
[125I][DES-GLY10,D-ALA6]GNRH N-ETHYLAMIDE
[125I][TYR5,DALA6,NMELEU7,PRO9-NET]GNRH
[AC-D-2NAL1,D4CPA2,D-3PAL3,6,LEU8, D-ALA10]GNRH-II
[D-LYS6]GNRH-II
[GLN8]GNRH
[HIS5,D-TYR6]GNRH
[SER8]GNRH
[TRP8]GNRH
[TYR8]GNRH
ANFIBATIDE
GLENZOCIMAB
PR-15
A33 131I
HUA33
KRN-330
CHEMBL:CHEMBL583611
COMPOUND 11D [PMID: 34406006]
COMPOUND 15 [PMID: 25411721]
COMPOUND 77A [PMID: 37639383]
INT-767
SODIUM TAUROCHOLATE
TAUROLITHOCHOLIC ACID-3-SULPHATE
XYT528B
ANTI-GLYPICAN 3/CD3 BISPECIFIC ANTIBODY ERY974
ANTI-GPC3-CAR AUTOLOGOUS T LYMPHOCYTES
CODRITUZUMAB
G-1
G15
G36
GLEMBATUMUMAB
GLEMBATUMUMAB VEDOTIN
(R)-N-OLEOYLTYROSINOL
(S)-N-OLEOYLTYROSINOL
1-OLEOYL GLYCEROL
1-PALMITOYL-LYSOPHOSPHATIDYLCHOLINE
1-STEAROYL-LYSOPHOSPHATIDYLCHOLINE
2-OLEOYL GLYCEROL
APD668
AR231453
AS1269574
AS1535907
AS1907417
BMS-903452
COMPOUND 1 [PMID: 21273063]
COMPOUND 1 [PMID: 21939274]
COMPOUND 2 [PMID: 21939274]
COMPOUND 20F [PMID: 21536438]
COMPOUND 23 [PMID: 21444206]
COMPOUND 29A [PMID: 21444206]
COMPOUND 3 [PMID: 21310611]
COMPOUND 36 [PMID: 21273063]
COMPOUND 36J [PMID: 21536438]
COMPOUND 3A [PMID: 21444206]
COMPOUND 3J [PMID: 21444206]
COMPOUND 42 [PMID: 22545772]
COMPOUND 58 [PMID: 21273063]
COMPOUND 8G [PMID: 21444206]
FIRUGLIPEL
GSK-1292263
JNJ-38431055
LYSOPHOSPHATIDYLETHANOLAMINE A glycerophosphoethanolamine resulting from partial hydrolysis of a phosphatidylethanolamine, which removes one of the fatty acid groups. The structure is depicted in the image where R(1) = acyl, R(2) = H or where R(1) = H, R(2) = acyl.
LYSOPHOSPHATIDYLINOSITOL
MBX-2982
OLEOYL-LYSOPHOSPHATIDYLCHOLINE
PALMIDROL
PSN375963
PSN632408
SEA
VANOGLIPEL
YH18968
CHEMBL:CHEMBL496266
CYCLOCITRINOL
NEOCYCLOCITRINOL B
NEOCYCLOCITRINOL C
SPHINGOSINE 1-PHOSPHATE A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1
SPHINGOSYLPHOSPHORYLCHOLINE
9-HYDROXYOCTADECADIENOIC ACID
NOX-6-18
NOX-6-7
ONC212
COMPOUND 1A [PMID: 24900311]
JNJ-63533054
LP-360924
LP-471756
NCRW0005-F05
NCRW0105-E06
ZELATRIAZIN (TAK-041)
COMPOUND 33 [TODA ET AL., 2013]
GPR15L
GPR15L (71-81)
ASN02563583
ASN04421891
ASN04450772
ASN04885796
ASN06917370
GTP
UDP-GALACTOSE
UDP-GLUCOSE
URIDINE-5'-DIPHOSPHATE
LYSOPHOSPHATIDYLSERINE An acylglycerophosphoserine resulting from partial hydrolysis of a phosphatidylserine, which removes one of the fatty acid groups. The structure is depicted in the image where R(1) = acyl, R(2) = H or where R(1) = H, R(2) = acyl.
ABNORMAL CANNABIDIOL
ARACHIDONYLCYCLOPROPYLAMIDE
O-1602
PSB-KD107
PSB-KK1415
PSB-KK1445
25-HYDROXYCHOLESTEROL A 25-hydroxy steroid that has formula C27H46O2.
27-HYDROXYCHOLESTEROL
7&ALPHA;,25-DIHYDROXYCHOLESTEROL
7&ALPHA;,27-DIHYDROXYCHOLESTEROL
7&ALPHA;-HYDROXYCHOLESTEROL
7&BETA;, 25-DIHYDROXYCHOLESTEROL
7&BETA;, 27-DIHYDROXYCHOLESTEROL
7&BETA;-HYDROXYCHOLESTEROL
COMPOUND 32 [PMID: 38047891]
GSK682753A
NIBR189
NIBR51
ADROPIN
COMPOUND 1A [PMID: 27184081]
COMPOUND 5128535
PT-91
DIPHENYLENEIODONIUM CHLORIDE
RTI-19318-32
[3H]RESOLVIN D1
YL-365
2-OLEOYL-LPA
CHEMBL:CHEMBL107513
CHEMBL:CHEMBL394883
CID2745687
COMPOUND 83 [PMID: 23888932]
CXCL17
LODOXAMIDE
NEUROPEPTIDE HEAD ACTIVATOR
PROSAPTIDE
COMPOUND 1 [PMID: 24900608]
COMPOUND 15 [PMID: 25313322]
GPR4 ANTAGONIST 3B
NE 52-QQ57
LITTLELEN
COMP-43
COMPOUND 7A [PMID: 24884590]
DERIVATIVE 17 [NAKAHATA ET AL., 2018]
NXE0041178
2-ARACHIDONOYLGLYCEROLPHOSPHOINOSITOL
CHEMBL:CHEMBL528068
CHGB (511-532)
CID1172084
CID16020046
CID1792197
CID2440433
CLUL1 (52-77)
COMPOUND 3A [BADOLATO ET AL., 2019]
CP55,244
CP55,667
GSK494581A
GSK575594A
MANSC (415-431)
ML193
MSMB (91-114)
O-ARACHIDONOYL ETHANOLAMINE
SPAG11B (61-103)
T1117
[3H]RIMONABANT
EXAMPLE 31 [WO2018183145]
EXAMPLE 494 [WO2014028479] PARENT MOLECULE
SOLENGEPRAS
COMPOUND 1 [PMID: 37741852]
DIHYDROSPHINGOSINE 1-PHOSPHATE
DIOLEOYLPHOSPHATIDIC ACID
CARTPT (76-96)
MS48107
OGERIN
OSTN (115-133)
POMC (141-162)
2-HYDROXY CAPRIC ACID
2-HYDROXYLAURIC ACID A monohydroxy fatty acid with a lauric acid core substituted at position 2 by a hydroxy group, which confers chirality; a component of cellular lipids in Pseudomonas strains.
3-HYDROXY CAPRIC ACID
3-HYDROXYLAURIC ACID A medium-chain fatty acid that is the 3-hydroxylated derivative of lauric acid; associated with fatty acid metabolic disorders.
6-N-OCTYLAMINOURACIL
6-NONYLPYRIDINE-2,4-DIOL
DECANOIC ACID
DIM
DL-175
GLPG-1205
GLPG1205
LAURIC ACID A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
OX04529
PBI-4547
PSB-1584
PSB-16434
PSB-17365
TUG-2181
UNDECANOIC ACID A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series.
ZQ-16
DIOCTANOYLGLYCEROL PYROPHOSPHATE
KI16425
LPA lipoprotein, Lp(a)|The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]
COMPOUND 2 [PMID: 24793972]
RTI-122
RTI-13951-33
ARGININE
CITRULLINE
LYSINE
ORNITHINE, (L)-ISOMER
SERINE
GPX4 INHIBITOR C18
ML162
ARGIOTOXIN
ATPO
BECAMPANEL
CX-717
CX1739
CX516
CX546
DASOLAMPANEL
FARAMPATOR
FLUORO-WILLARDIINE
GYKI53655
IDRA-21
IRAMPANEL
JORO SPIDER TOXIN
LY392098
LY404187
LY503430
MIBAMPATOR
MK-8777
OSAVAMPATOR
PESAMPATOR
PIRACETAM
S18986
SELURAMPANEL
TALAMPANEL A benzodioxole that has formula C19H19N3O3.
TEZAMPANEL
ZONAMPANEL
[3H]CNQX
4‐BCCA
PALIRODEN
2,4-EPI-NEODYSIHERBAINE
2-AMINO-3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]-4-ISOXAZOLYL)PROPIONIC ACID
8-DEOXY-NEODYSIHERBAINE
ACET
ATPA
CONCANAVALIN A
DOMOIC ACID A L-proline derivative that is L-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,4-dien-2-yl group at position 4. It is an analog of kainic acid and is the neurotoxin associated with the amnesic shellfish poisoning (ASP).
LY339434
LY382884 An alpha-amino acid that has formula C18H23NO4.
LY466195
MSVIII-19
NS3763
SYM2081
[3H]KAINATE
[3H]SYM2081
[3H]UBP310
BPAM344
DYSIHERBAINE
(+)-HA966
(RS)-(TETRAZOL-5-YL)GLYCINE
APIMOSTINEL
ASPARTIC ACID
AV-101
AZD8108
CNS-5161
COMPOUND 8 [PMID: 17562362}
DELUCEMINE
DEXANABINOL
ESKETAMINE
ESKETAMINE HYDROCHLORIDE
EVT-101
GW468816
HOMOQUINOLINIC ACID
INDANTADOL
KETAMINE HYDROCHLORIDE
LANICEMINE
NEBOGLAMINE
ORPHENADRINE A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.
ORPHENADRINE HYDROCHLORIDE
PERZINFOTEL
PHILANTHOTOXIN 343
RADIPRODIL
RAPASTINEL
RISLENEMDAZ
TRAXOPRODIL
[3H]CGP39653
[3H]CGP61594
[3H]CGS19755
[3H]CPP
[3H]D-ASPARTIC ACID
[3H]DIZOCILPINE
[3H]L689560
CGP37849
CONANTOKIN-G
D-AP5
D-CCPENE
DIMIRACETAM
GV196771A
L689560
LY233053
MG2+
N1-DANSYL-SPERMINE
NERAMEXANE
NVP-AAM077
NYX-2925
PHENCYCLIDINE A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
PLAZINEMDOR
SAGE-718
SELFOTEL An alpha-amino acid that has formula C7H14NO5P.
TCN-201
UBP141
[3H]MDL105519
NP-10679
ONFASPRODIL
S-DESCHLOROKETAMINE
DEXTRORPHAN A morphinane alkaloid that has formula C17H23NO.
LEVORPHANOL
BALANOL
CCG258747
COMPOUND 101 [PMID: 21596927]
COMPOUND 1O [PMID: 24210504]
GSK180736A
(S)-4C3HPG
A-794278
A-794282
A-841720
A-850002
CFMMC
CFMTI
CIS-10 [PMID: 15771457]
COMPOUND 10I [PMID: 23084894]
COMPOUND 11C [PMID: 17929793]
COMPOUND 11Q [PMID: 19433355]
COMPOUND 11S [PMID: 19433355]
COMPOUND 12E [PMID: 22266036]
COMPOUND 22 [PMID: 17276684]
COMPOUND 23C [PMID: 17929793]
COMPOUND 23E [PMID: 17929793]
COMPOUND 23H [PMID: 17929793]
COMPOUND 23I [PMID: 17929793]
COMPOUND 24 [PMID: 20346665]
COMPOUND 27 [PMID: 20346665]
COMPOUND 2F [PMID: 17532216]
COMPOUND 9A [PMID: 22266036]
COMPOUND 9N [PMID: 23084894]
CPCCOET
FTIDC
JNJ16259685
LY341495
LY456066
LY456236
MK-5435
PHCCC
VU0469650
VU0483605
YM298198
[11C]MMTP
[18F]FITM
[18F]MK-1312
[3H]R214127
(+)-MCPG
(1S,3R)-ACPD
(2R,3R)-APDC
3-MPPTS
4-APPES
4-MPPTS
AZD8529
BIPHENYLINDANONE A
CBIPES
COMPOUND 2 [PMID: 21105727]
COMPOUND 3 [PMID: 21105727]
COMPOUND 34 [PMID: 20409708]
COMPOUND 4 [PMID: 21105727]
COMPOUND 48 [PMID: 22364337]
CYPPTS
DCG-IV
DECOGLURANT
EGLUMETAD
GSK1331258
GSK1331268
JNJ-40068782
JNJ-40411813
JNJ-42153605
JNJ-46281222
LY2969822
LY2979165
LY379268
LY395756
LY404039
MGS-0210
MNI-135
MNI-136
MNI-137
OLEOYL-ESTRONE
POMAGLUMETAD METHIONIL ANHYDROUS
PTBE
RO4491533
THIIC
[3H]2,2,2-TEMPS
[3H]JNJ-40068782
[3H]LY341495
LY2389575
VU0650786
(R,S)-4-PPG
(S)-3,4-DCPG
ADX88178
CHEMBL:CHEMBL541754
CHEMBL:CHEMBL549330
CHEMBL:CHEMBL559271
CHEMBL:CHEMBL571453
CHEMBL:CHEMBL572346
COMPOUND 1 [PMID: 22465637]
COMPOUND 11 [PMID: 20638279]
COMPOUND 22A [PMID: 21688779]
COMPOUND 7 [PMID: 20638279]
DEXFOSFOSERINE
FOLIGLURAX
FP0429
L-AP4
LSP4-2022
LU AF21934
MPEP
VU0080241
VU0092145
VU0155041
VU0359516
VU0361737
VU0364770
VU0400195
VU2957
5PAM523
ACDPP
ADX-47273
AZD2066
AZD2516
AZD6538
AZD9272
BASIMGLURANT
BOMA
CDPPB
CHPG
COMPOUND 10 [PMID: 15482906]
COMPOUND 10 [PMID: 15482908]
COMPOUND 11A [PMID: 14697765]
COMPOUND 13 [PMID: 15686941]
COMPOUND 16A [PMID: 14697765]
COMPOUND 16M [PMID: 19931453]
COMPOUND 18 [PMID: 21927650]
COMPOUND 24 [PMID: 23374867]
COMPOUND 24D [PMID: 23357634]
COMPOUND 29B [PMID: 20809633]
COMPOUND 30 [PMID: 21757343]
COMPOUND 41 [PMID: 23434029]
COMPOUND 47 [PMID: 21295468]
COMPOUND 53 [PMID: 23434029]
COMPOUND 8 [PMID: 15482908]
CPPHA
CPPZ
CTEP
DASOLAMPANEL ETIBUTIL
DIPRAGLURANT
FENOBAM ANHYDROUS
GRN-529
GSK2210875
LSN2463359
LSN2814617
MAVOGLURANT
MTEB
MTEP
PTEB
RASEGLURANT
RG7342
STX-107
STX107
TMP-301
VU-1545
VU0360172
VU0404251
VU0409551
[3H]CTEP
[3H]M-MPEP
HOMO-AMPA
MPPG
&ALPHA;-METHYLSERINE-O-PHOSPHATE
ADX71743
AMN082
MAP4 microtubule-associated protein 4|The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
MCCG
MSOPPE
PPG
VU6012962
XAP044
AZ12216052
D-AP4
VU0155094
VU0422288
(D-ALA11]BOMBESIN
AC-GRP-(20-26)-METHYLESTER
AM-37
BAY86-7548
BOMBESIN
D-NAL,CYS,TYR,D-TRP,ORN,VAL,CYS,NAL-NH2
GASTRIN RELEASING PEPTIDE(14-27) (HUMAN)
GASTRIN-RELEASING PEPTIDE
LITORIN
NEUROMEDIN B
NEUROMEDIN B (1-30) (HUMAN)
NEUROMEDIN C
PD 168368
PD 176252
PHYLLOLITORIN
RANATENSIN
RHODEI-LITORIN
[(3-PH-PR6), HIS7,D-ALA11,D-PRO13,&PSI;13-14),PHE14]BOMBESIN-(6-14)
[125I]GRP (HUMAN)
[125I][TYR4]BOMBESIN
[D-ARG1,D-TRP7,9,LEU11]SUBSTANCE P
[D-PHE6, LEU13, CPA14,&PSI;13-14]BOMBESIN-(6-14)
[D-PHE6, STAT13, LEU14]BN(6-14)
[D-PHE6]BOMBESIN(6-13)METHYL ESTER
[D-PHE6]BOMBESIN(6-13)PROPYLAMIDE
[D-PRO4,D-TRP7,9,10]SUBSTANCE P (4-11)
[D-TPI6, LEU13 &PSI;(CH2NH)-LEU14]BOMBESIN-(6-14)
[D-TYR6,&BETA;-ALA11,N-ME-ALA13,NLE14]BOMBESIN-(6-14)
[LEU14, &PSI; 13-14)]BOMBESIN
[LEU14]BOMBESIN
[LEU8]-PHYLLOLITORIN
[PHE13]BOMBESIN
ANIDULAFUNGIN
CASPOFUNGIN ACETATE
IBREXAFUNGERP
IBREXAFUNGERP CITRATE
MICAFUNGIN SODIUM
LDC7559
AZD1080
CHIR-98014
LITHIUM CARBONATE A carbonate salt that has formula CO3.2Li.
LITHIUM CITRATE
RUCAPARIB METABOLITE M324
TIDEGLUSIB
AZD2858
BETA SITOSTEROL
CHEMBL:CHEMBL1081326
CHEMBL:CHEMBL449063
COMPOUND 4-3 [PMID: 34027661]
COMPOUND 4G [PMID: 2680437]
COMPOUND 5 [PMID: 19338355]
ELRAGLUSIB
GOMISIN N
GSK-3&BETA; INHIBITOR 3 [PMID: 25845281]
GSK-3BETA INHIBITOR I
GSK-3BETA INHIBITOR II
IM-12
MANZAMINE A
PALBINONE
PALINURIN
SITOGLUSIDE
TWS119
MISONIDAZOLE
NOV-002
[3H]BSP
ANTITUBERCULAR AGENT
SULFAMETHOXAZOLE / TRIMETHOPRIM
C1-27
COMPOUND 25 [PMID: 32105470]
CANFOSFAMIDE
CANFOSFAMIDE HYDROCHLORIDE
DIMETHYL FUMARATE An enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis.
DL-SELENOMETHIONINE
EXATECAN MESYLATE
EZATIOSTAT
EZATIOSTAT HYDROCHLORIDE
DICHLOROACETIC ACID An organochlorine compound comprising acetic acid carrying two chloro substituents at the 2-position. It occurs in nature in seaweed, Asparagopsis taxiformis.
DEFERITAZOLE
ETIDRONATE DISODIUM
ATACIGUAT
CINACIGUAT
OLINCIGUAT
PRALICIGUAT
RIOCIGUAT
RUNCACIGUAT
SODIUM NITROPRUSSIDE
VERICIGUAT
NITRIC OXIDE-RELEASING ACETYLSALICYLIC ACID DERIVATIVE
DOLCANATIDE
E. COLI HEAT-STABLE ENTEROTOXIN (STA)
GUANYLIN
INDUSATUMAB VEDOTIN
LINACLOTIDE
PLECANATIDE
UROGUANYLIN
[125I]STA
GUANYLYL CYCLASE-ACTIVATING PROTEIN 1
GUANYLYL CYCLASE-ACTIVATING PROTEIN 2
VESTRONIDASE ALFA
FRAMYCETIN
YESSOTOXIN
VARICELLA ZOSTER VIRUS ENVELOPE GLYCOPROTEIN E
COMPOUND 20 [PMID:12127536]
LEXAPTEPID PEGOL
LY-2787106
ANTI-TIM-3 MONOCLONAL ANTIBODY
ANTI-TIM3 MONOCLONAL ANTIBODY LY3321367
COBOLIMAB
LOMVASTOMIG
PD1 INHIBITOR
SABATOLIMAB
EFAPROXIRAL
AES-103
BETIBEGLOGENE AUTOTEMCEL
CRIZANLIZUMAB
LOVOTIBEGLOGENE AUTOTEMCEL
LUSPATERCEPT
NEBULARINE A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.
ANTI-HBEGF MONOCLONAL ANTIBODY U3-1565
KHK-2866
3,5-DIHYDROXYBENZOIC ACID A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 5.
4-HYDROXYBUTYRIC ACID A 4-hydroxy monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a hydroxy group.
COMPOUND 2 [PMID: 24486398]
COMPOUND 2 [PMID: 31932225]
D-LACTIC ACID
L-LACTIC ACID
&BETA;-D-HYDROXYBUTYRIC ACID
(+)-5-(5-BROMOTHIOPHEN-3-YL)-5-METHYL-4-OXO-4,5-DIHYDRO-FURAN-2-CARBOXYLIC ACID
3-PYRIDINE-ACETIC ACID
5-METHYL NICOTINIC ACID
ACIFRAN
ACIPIMOX
CINNAMIC ACID A monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. It is found in Cinnamomum cassia.
COMPOUND (+)17A [PMID: 20363624]
COMPOUND 1Q [PMID: 18029181]
COMPOUND 21 [PMID: 21185185]
COMPOUND 245A
COMPOUND 2G [PMID: 19309152]
COMPOUND 42 [PMID: 22420767]
COMPOUND 4A [PMID: 17452318]
COMPOUND 780A
COMPOUND 8F [PMID: 20615702]
COMPOUND 9N [PMID: 18752940]
GSK256073
MK 0354
MK 1903
MK 6892
MK-0354
MONOMETHYL FUMARATE
PARA-COUMARIC ACID
SCH 900271
SCH-900271
(S)-3-PHENYLLACTIC ACID
2-HYDROXYOCTANOIC ACID
3-HYDROXYOCTANOIC ACID An 8-carbon, beta-hydroxy fatty acid which may be a marker for primary defects of beta-hydroxy fatty acid metabolism. Repeating unit of poly(3-hydroxyoctanoic acid), a biopolymer used by numerous bacterial species as carbon and energy reserves.
4-(N-PROPYL)AMINO-3-NITROBENZOIC ACID
5-METHYL-5-(5-METHYLTHIOPHEN-3-YL)-4-OXO-4,5-DIHYDROFURAN-2-CARBOXYLIC ACID
COMPOUND 5B [PMID: 17358052]
COMPOUND 6O [PMID: 19524438]
D-KYNURENINE
D-PHENYLALANINE The D-enantiomer of phenylalanine.
D-TRYPTOPHAN The D-enantiomer of tryptophan.
IBC 293
CILOBRADINE
CS+
ZATEBRADINE
ZD7288
EC18
IVABRADINE HYDROCHLORIDE
MEL57A
(R)-YNT-3708
1-SORA-51
ACT-335827
ACT-462206
ALMOREXANT
COMPOUND 1 [PMID: 33547286]
COMPOUND 11 [PMID: 15261275]
CP-1
CVN45502
CVN766
DANAVOREXTON
DARIDOREXANT
DARIDOREXANT HYDROCHLORIDE
EMPA
FAZAMOREXANT
FILOREXANT
FIRAZOREXTON
HTL6641
JH112
JNJ-10397049
LEMBOREXANT
LSN2424100
MK-1064
MK-3697
NAG 26
NIVASOREXANT
OREXIN-A
OREXIN-B
ORN-0829 HYDRATE
OVEPOREXTON
RTOXA-43
SB-410220
SB-649868
SB-674042
SELTOREXANT
SUVOREXANT An aromatic amide obtained by formal condensation of the carboxy group of 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid with the secondary amino group of 5-chloro-2-[(5R)-5-methyl-1,4-diazepan-1-yl]-1,3-benzoxazole. An orexin receptor antagonist used for the management of insomnia.
TCS 1102
VORNOREXANT
YNT-185
[125I]OREXIN A (HUMAN, MOUSE, RAT)
[3H]-ALMOREXANT
[3H]-TCS 1102
[3H]SB-674042
[ALA11, D-LEU15]OREXIN-B
ALIXOREXTON
T-516
TCS-OX2-29
[3H]CP-1
[3H]EMPA
[3H]T-516
ABEXINOSTAT
ACY-738
APICIDIN
AR-42
BML-281
BUTYRYLHYDROXAMIC ACID
CARBOXYCINNAMIC ACID BISHYDROXAMIDE
CHEMBL:CHEMBL117487
CHEMBL:CHEMBL1650245
CHEMBL:CHEMBL324053
CHIDAMIDE
CHLAMYDOCIN
CHR-3996
CITARINOSTAT
COMPOUND 23F [ZHANG ET AL., 2025]
DACINOSTAT
DEPUDECIN
GIVINOSTAT
GIVINOSTAT HYDROCHLORIDE
HC-TOXIN
J27644
KA1010
MARTINOSTAT
NEXTURASTAT A
OBP-801
PANOBINOSTAT LACTATE
PHENYLBUTYRYLHYDROXAMIC ACID
PIVALOYLOXYMETHYLBUTYRATE
PRACINOSTAT
PSAMMAPLIN A
RESMINOSTAT
RG-2833
RGFP109
RICOLINOSTAT
SPIRUCHOSTATIN C
SS-208
SUBEROHYDROXAMIC ACID
SUPRASTAT
TACEDINALINE
TUCIDINOSTAT
COMPOUND 30 [PMID: 37057760]
CINNAMIC ACID HYDROXAMATE
MARBOSTAT-100
SANTACRUZAMATE A
DROXINOSTAT
RGFP966
TASQUINIMOD
TMP269
BAVAROSTAT
BENZOHYDROXAMATE
CHEMBL:CHEMBL569419
COMPOUND 16 [PMID: 20947351]
COMPOUND 35M [PMID: 36073117]
COMPOUND 7D [PMID: 19111466]
KA2507
NICOXAMAT
NQN-1
TUBACIN
TYA-018
VALPROPYLHYDROXAMIC ACID
SZUH280
CG-200745
GSK-3117391
REMETINOSTAT
TINOSTAMUSTINE
ZABADINOSTAT
AMA
FMH
ECHINOMYCIN
THIOCORALINE A peptide that has formula C48H56N10O12S6.
CORTISONE A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.
IRON CARBONYL
ANTI-HGF MONOCLONAL ANTIBODY TAK-701
FICLATUZUMAB
NANOPARTICLE ALBUMIN-BOUND THIOCOLCHICINE DIMER NAB-5404
RILOTUMUMAB
VEGF/HGF-TARGETING DARPIN MP0250
AMFONELIC ACID
ANTI-HIF-1ALPHA LNA ANTISENSE OLIGONUCLEOTIDE EZN-2968
CHEMBL:CHEMBL1356607
CHEMBL:CHEMBL1438389
CHEMBL:CHEMBL253989
CHEMBL:CHEMBL451226
DAVAMOTECAN PEGADEXAMER
ENMD-1198
ISOCEPHAELINE
KLUGINE
MANASSANTIN B
PIMONIDAZOLE
PX-478
VADIMEZAN A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 5,6-dimethyl-9-oxoxanthen-4-yl group.
2,6-DIMETHOXYQUINONE
CHEMBL:CHEMBL1865517
BACAMPICILLIN
BENZNIDAZOLE
FLOXACILLIN
POLYVALENT MELANOMA VACCINE
TETANUS ANTITOXIN
VANCOMYCIN A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.
CEFTAZIDIME ANHYDROUS
MEASLES VACCINE
PENICILLIN V
RALTEGRAVIR POTASSIUM
TRICHLOROETHYLENE
VELIMOGENE ALIPLASMID
THERAPEUTIC TUMOR INFILTRATING LYMPHOCYTES
BUCILLAMINE
1D09C3
ANAKINRA
APOLIZUMAB
CANAKINUMAB
INFLUENZA VACCINE
LYM-1
PLOVAMER ACETATE
RILONACEPT
TEGAFUR/GIMERACIL/OTERACIL
CD24FC
DNA INTERCALATING AGENT
STALLIMYCIN
SULFURIC ACID
ATORVASTATIN CALCIUM
COMPOUND 1 [PATEL ET AL., 1991]
COMPOUND 11JJ [PMID: 1656041]
COMPOUND 11NN [PMID: 1656041]
COMPOUND 17 [PMID: 15686906]
COMPOUND 18 [PMID: 8426367]
COMPOUND 1A [PMID: 2153213]
COMPOUND 1E [PMID: 2153213]
COMPOUND 1F [PMID: 2153213]
COMPOUND 2 [DREYER ET AL., 1991]
COMPOUND 29 [PMID: 1527791]
COMPOUND 29 [PMID: 15686906]
COMPOUND 2C [PMID: 2153213]
COMPOUND 2D [PMID: 2153213]
COMPOUND 2F [PMID: 2153213]
COMPOUND 2T [PMID: 2296036]
COMPOUND 3 [DREYER ET AL., 1991]
COMPOUND 33 [PMID: 17574412]
COMPOUND 41 [PMID: 17574411]
COMPOUND 42 [PMID: 17574411]
COMPOUND 4FF [PMID: 1656041]
COMPOUND 4I [PMID: 2296036]
COMPOUND 6A [PATIL ET AL., 1989]
COMPOUND 9 [PMID: 1992149]
COMPOUND 9A [PATIL ET AL., 1989]
CRILVASTATIN
DFGYVAE
FLUVASTATIN SODIUM
FPYVAE PEPTIDE [PMID: 20494585]
GLPDGG PEPTIDE [PMID: 20494585]
HMG-COA REDUCTASE INHIBITOR
LAROPIPRANT
PITAVASTATIN MAGNESIUM
PITAVASTATIN SODIUM
ROSUVASTATIN CALCIUM
TOCOTRIENOLS
(S)-3-HYDROXY-3-METHYLGLUTARYL-COA
COMPOUND 1 [PMID: 16821802]
STANNSOPORFIN
NORLEUCINE
ALVERINE
BENFLUOREX
BI6015
CHEMBL:CHEMBL482792
HNF4&ALPHA; INHIBITOR
METOPRINE
HEPATITIS B VACCINE
NITISINONE
2',BETA-DIHYDROXYCHALCONE
2-BENZOYL-5-METHOXYBENZOQUINONE
3,4-DIMETHOXYDALBERGIONE
7-CHLOROKYNURENIC ACID A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
CEAROIN
CHEMBL:CHEMBL1368535
CHEMBL:CHEMBL1485420
CHEMBL:CHEMBL502257
CHEMBL:CHEMBL529138
CHLORPROPHAM A carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid.
CLORGYLINE HYDROCHLORIDE
COMPOUND 3 [PMID: 21650226]
DEMETHYLENCECALIN
DIETHYLTOLUAMIDE
FPL-55712
LEOIDIN
MECYSTEINE HYDROCHLORIDE
ML148
NORSTICTIC ACID
PEUCENIN
PHENAMIPHOS
REV-5901
SUPROFEN METHYL ESTER
THIORPHAN A N-acyl-amino acid that has formula C12H15NO3S.
TOLMETIN SODIUM
TRICLOFENOL
4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE
TFC007
BENTIROMIDE
NITROSOUREA COMPOUND
AMOPYROQUINE
PIXATIMOD
HISTAMINE PHOSPHATE A phosphate salt that is the diphosphate salt of histamine.
LEVOMEQUITAZINE
REPIRINAST
AZD8186
GANITUMAB
ISIS 2503
ISIS-2503
L-744,832
MRTX-1133
MTOR KINASE INHIBITOR AZD8055
OPNURASIB
PELAREOREP
RIGOSERTIB
RIGOSERTIB SODIUM
SF1126
SOTORASIB
SR9009
SR9011
(&PLUSMN;)-CIS-H2-PAT
(&PLUSMN;)-TRANS-H2-PAT
(+)-CIS-H2-PAT
(-)-TRANS-H2-PAT
(S)-CETIRIZINE
2-(2-THIAZOLYL)ETHANAMINE
2-(3-BROMOPHENYL)HISTAMINE
2-(3-CHLOROPHENYL)HISTAMINE
2-(3-IODOPHENYL)HISTAMINE
2-PYRIDYLETHYLAMINE An aminoalkylpyridine that is pyridine substituted by a ethanamino group at position 2.
9-OH-RISPERIDONE
A-317920
A-349821
ABT-239
ACEPROMETAZINE
ACRIVASTINE
ALCAFTADINE
ANTAZOLINE PHOSPHATE
ARPROMIDINE
AZATADINE
AZATADINE MALEATE
AZELASTINE A phthalazine compound having an oxo substituent at the 1-position, a 1-methylazepan-4-yl group at the 2-position and a 4-chlorobenzyl substituent at the 4-position.
BEPOTASTINE BESILATE
BEPOTASTINE BESYLATE
BETAHISTINE
BILASTINE
BROMODIPHENHYDRAMINE
BROMODIPHENHYDRAMINE HYDROCHLORIDE
BROMPHENIRAMINE MALEATE
BU-E 47
BUCLIZINE HYDROCHLORIDE
CARBINOXAMINE MALEATE
CAREBASTINE
CHEMBL:CHEMBL1923521
CHLOPHEDIANOL
CHLORPHENIRAMINE MALEATE
CHLORPHENIRAMINE POLISTIREX
CHLORPHENOXAMINE
CIPROXIFAN
CONESSINE
CYCLIZINE
CYCLIZINE LACTATE
DESLORATADINE Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.
DEXBROMPHENIRAMINE MALEATE
DEXCHLORPHENIRAMINE MALEATE
DIBENZEPIN
DIMETHINDENE
DIMETHYLHISTAPRODIFEN
DIPHENHYDRAMINE CITRATE
DIPHENHYDRAMINE HYDROCHLORIDE
DIPHENYLPYRALINE HYDROCHLORIDE
DOXEPIN A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
DOXYLAMINE SUCCINATE
EMEDASTINE
EMEDASTINE DIFUMARATE
EPINASTINE HYDROCHLORIDE
GSK-1004723
HISTAPRODIFEN
HYDROXYZINE HYDROCHLORIDE
IMPROMIDINE
INCB-38579
JNJ-39758979
LEVOCABASTINE
LEVOCABASTINE HYDROCHLORIDE
LEVOCETIRIZINE
LEVOCETIRIZINE DIHYDROCHLORIDE
LY-2624803
LY2624803
MECLIZINE HYDROCHLORIDE
MEQUITAZINE
METHAPYRILENE FUMARATE
METHAPYRILENE HYDROCHLORIDE
METHDILAZINE
METHDILAZINE HYDROCHLORIDE
METHYLHISTAPRODIFEN
MIZOLASTINE
MK-0249
NOBERASTINE
OLOPATADINE
OLOPATADINE HYDROCHLORIDE
OXO-ARPROMIDINE
PEMIROLAST
PHENINDAMINE
PHENIRAMINE
PHENIRAMINE MALEATE
PIPAMPERONE
PROPIOMAZINE HYDROCHLORIDE
PYRILAMINE MALEATE
RUPATADINE
ST-1006
THENALIDINE
TRIMEPRAZINE
TRIMEPRAZINE TARTRATE
TRIPELENNAMINE
TRIPELENNAMINE CITRATE
TRIPELENNAMINE HYDROCHLORIDE
TRIPROLIDINE HYDROCHLORIDE
UR-PG131A
UR-PG146
UR-PG153
UR-PG55B
VAPITADINE
VAPITADINE DIHYDROCHLORIDE
[3H]PYRILAMINE
AMTHAMINE
BETAZOLE Pyrazole in which a hydrogen adjacent to one of the nitrogen atoms is substituted by a 2-aminoethyl group. It is a histamine H2-receptor agonist used clinically to test gastric secretory function.
BETAZOLE HYDROCHLORIDE
BURIMAMIDE An imidazole that has formula C9H16N4S.
CIMETIDINE HYDROCHLORIDE
EBROTIDINE
LAFUTIDINE
METHANTHELINE BROMIDE
NIZATIDINE
RANITIDINE BISMUTH CITRATE Complex of ranitidine, trivalent bismuth, and citrate. CAS#128345-62-0.
(R)-&ALPHA;-METHYLHISTAMINE
(S)-&ALPHA;-METHYLHISTAMINE
A-304121
A331440
ABT-288
ADRIFORANT
BAVISANT
BODILISANT
CHEMBL:CHEMBL565540
CIPRALISANT
CIPRALISANT MALEATE
COMPOUND 3A [PMID: 18606542]
DIMAPRIT An imidothiocarbamic ester that has formula C6H15N3S.
ENERISANT
FUB 349
GR 175737
GSK-189254
GSK239512
GSK334429
GT2394
IMBUTAMINE
IMMEPIP A piperidine that has formula C9H15N3.
IMMETHRIDINE
IMPENTAMINE
IODOPROXYFAN
IRDABISANT
JB 98064
JNJ-17216498
JNJ-39220675
JNJ-5207852
METHIMEPIP
PF-03654746
PF-03654764
PITOLISANT HYDROCHLORIDE
PROXYFAN
ST-1478
ST-1505
SUVN-G3031
UCL-2138
VUF 4904
VUF 5207
VUF 8328
VUF14738
VUF14862
VUF15000
VUF26063
[123I]IODOPROXYFAN
2-METHYLHISTAMINE An aralkylamino compound that is histamine bearing a methyl substituent at the 2 position on the ring.
4-METHYLHISTAMINE An aralkylamino compound that is histamine bearing a methyl substituent at the 5 position on the ring.
CHEMBL:CHEMBL452847
CHEMBL:CHEMBL454890
H4 ANTAGONIST 48
HTMT
IMPROGAN
JNJ 7777120
JNJ-10191584
N,N-DIMETHYLHISTAMINE
N-&ALPHA;-METHYLHISTAMINE
N-ETHYLHISTAMINE
SELIFORANT
TOREFORANT
UR-63325
VOTUCALIS
VUF 8430
[125I]CCL16 (HUMAN)
ABT-384
AZD-4017
AZD8329
BI-187004
BMS-770767
BMS-816336
BMS-823778
CHEMBL:CHEMBL604538
INCB13739
MK-0736
TORMENTIC ACID METHYL ESTER
2'-METHOXYFORMONETIN
4-METHYLESCULETIN
5-FLUOROINDOLE-2-CARBOXYLIC ACID
6,4'-DIMETHOXYFLAVONE
ACETANILIDE
ALRESTATIN
AMILORIDE HYDROCHLORIDE
AMINACRINE
ANTHRANILIC ACID An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system.
ANTIMYCIN A A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison.
AURAPTENE
BENZO[E]PYRENE An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. It is listed as a Group 3 carcinogen by the IARC.
BILIRUBIN A member of the class of biladienes that is a linear tetrapyrrole, product of heme degradation. It is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.
BISSALICYL FUMARATE
BUTYL 2-AMINOBENZOATE
CARBAZOLE
CHEMBL:CHEMBL1500740
CHEMBL:CHEMBL1529609
CHEMBL:CHEMBL1576338
CHEMBL:CHEMBL1608067
CHEMBL:CHEMBL221721
CHEMBL:CHEMBL221733
CHEMBL:CHEMBL259421
CHEMBL:CHEMBL265715
CHEMBL:CHEMBL294878
CHEMBL:CHEMBL296021
CHEMBL:CHEMBL317869
CHEMBL:CHEMBL406834
CHEMBL:CHEMBL408850
CHEMBL:CHEMBL491550
CHEMBL:CHEMBL494081
CHEMBL:CHEMBL530149
CHEMBL:CHEMBL577887
CHEMBL:CHEMBL580381
CHEMBL:CHEMBL582081
CHEMBL:CHEMBL582355
CHEMBL:CHEMBL601764
CHEMBL:CHEMBL8488
CICHORIC ACID
CLADRIN
DIETHANOLAMINE
DIHYDRO-OBLIQUIN
ETHYL ANTHRANILATE
EVOXINE
FLUORANTHENE An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring.
FORMONONETIN A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'.
FR-122047
FRAXIDIN METHYL ETHER
GARCINOLIC ACID
HAPLAMINE
HARMALOL HYDROCHLORIDE
HERNIARIN
HOECHST 33258
HYDRASTININE HYDROCHLORIDE
HYDROXYTOLUIC ACID
HYMECROMONE METHYL ETHER
KHRINONE E
LEVDOBUTAMINE
LOMATIN
METHYL ANTHRANILATE
METOLAZONE
N-METHYLANTHRANILIC ACID
NAPHTHYLAMINE
O,O'-DIMETHYLCAFFEIC ACID
PADIMATE-O
PHTHALAZINONE
PINOSYLVIN METHYL ETHER
PYRENE An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.
SALICYLAMIDE The simplest member of the class of salicylamides derived from salicylic acid.
SALICYLURIC ACID An N-acylglycine in which the acyl group is specified as 2-hydroxybenzoyl.
SARAFLOXACIN HYDROCHLORIDE
SAVIRIN
SPHONDIN
STEARIC ACID A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
TRAZODONE HYDROCHLORIDE
TRIFLUSAL
XANTHOPTERIN
XANTHYLETIN
BI-3231
COMPOUND 24 [PMID: 31343176]
BIMOCLOMOL
ALVESPIMYCIN
ALVESPIMYCIN HYDROCHLORIDE
ARGENTEOSIDE A
AUY922
BROXYQUINOLINE
BUTOCONAZOLE NITRATE
CCT-018159 A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively.
CELASTROL
CEMDOMESPIB
CHEMBL:CHEMBL1834096
CHEMBL:CHEMBL192264
CHEMBL:CHEMBL2022241
CHEMBL:CHEMBL463701
CHEMBL:CHEMBL534423
CHEMBL:CHEMBL582983
CUCURBITACIN D
DESACETYL SALANNIN
EFUNGUMAB
GAMBOGIC ACID
HSP90 INHIBITOR BIIB021
HSP90 INHIBITOR DEBIO 0932
HSP90 INHIBITOR LAM-003A
KW-2478
MONOCILLIN I
RADANAMYCIN
RADICICOL An antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and heat shock protein 90 (Hsp90).
RETASPIMYCIN
RETASPIMYCIN HYDROCHLORIDE
SNX 5422
SNX-5422
SNX0723
TERCONAZOLE
TOTAROL
TOXYLOXANTHONE C
TRIADIMENOL
ZEARALANONE
COUMERMYCIN A1
CYCLOPROPARADICICOL
PIMITESPIB
PU-H71
COMPOUND 18C [PMID: 25901531]
GRP94 INHIBITOR 54
SEMAPIMOD
AG-858
MINNELIDE
PERILLYL ALCOHOL
PHOSPHODIESTERASE INHIBITOR
PORFIMER SODIUM
4-METHYLDAPHNETIN
CEREBRAL DOPAMINE NEUROTROPHIC FACTOR
IT-139
RUTHENIUM-BASED TRANSFERRIN TARGETING AGENT NKP-1339
STROBOPININ
ADP A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase.
CHEMBL:CHEMBL487046
FORIGERIMOD ACETATE
RHODACYANINE ANALOG MKT-077
APATORSEN
BENZENETHIOL
BUFOTENINE
CHEMBL:CHEMBL1935538
CHEMBL:CHEMBL2094499
CHEMBL:CHEMBL2332783
CYROMAZINE A triamino-1,3,5-triazine that has formula C6H10N6.
DICARBONODITHIOIMIDIC DIAMIDE
RHAMNETIN
THERAPEUTIC ESTROGEN
AZX-100
DIAPEP-277
(-)-TERTATOLOL
(R)-FLUROCARAZOLOL
(R)-UH 301
(S)-FLUROCARAZOLOL
1-NAPHTHYLPIPERAZINE
7-METHOXY-1-NAPHTHYLPIPERAZINE
BMY-14802
BRL-15572
CAPESEROD
CP 93129
CYAMEMAZINE
DEXFENFLURAMINE HYDROCHLORIDE
DONITRIPTAN
DU 125530
ELTOPRAZINE
EMDT
ENSACULIN HYDROCHLORIDE
FG-5893
FLESINOXAN
FLUPAROXAN
FROVATRIPTAN
GEPIRONE
GEPIRONE HYDROCHLORIDE
GR 125,743
GR 218,231
GSK-958108
GSK163090
L-772,405
LECOZOTAN HYDROCHLORIDE
LY 165,163
LY293284
LY344864
LYSERGIDE
MPDT
NALUZOTAN
NARATRIPTAN A heteroarylpiperidine that has formula C17H25N3O2S.
NLX-101
OPC-14523
OSEMOZOTAN
P-MPPI
P-[18F]MPPF
PICLOZOTAN
PIROMELATINE
PIZOTYLINE
REC 15/3079
REPINOTAN
RIZATRIPTAN BENZOATE
ROBALZOTAN
RS-30199
S 16924
S-14506
S-14671
S-15535
SB 216641
SB 272183
SB 649915
SB 714786
SDZ-216525
TANDOSPIRONE
TIOSPIRONE
U92016A
WAY-100135
XALIPRODEN A tetrahydropyridine that has formula C24H22F3N.
ZALOSPIRONE
ZIMELDINE HYDROCHLORIDE
ZOLMITRIPTAN
[11C]WAY100635
[3H]LY334370
[3H]NLX-112
[3H]P-MPPF
[3H]ROBALZOTAN
2-METHYL-5-HT
5-(NONYLOXY)-TRYPTAMINE
5-HT-MODULINE
ALMOTRIPTAN
ALMOTRIPTAN MALATE
ALNIDITAN
AVITRIPTAN
BMS 181,101
CP-122288
CP94253
DIPROPYL-5-CT
DRUGSATFDA.NDA:016727
ELETRIPTAN HYDROBROMIDE
ELZASONAN HYDROCHLORIDE
FROVATRIPTAN SUCCINATE
L-775,606
LYSERGOL An alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at C-8.
NARATRIPTAN HYDROCHLORIDE
NXN-188
SB 224289 A member of the class of benzamides obtained by formal condensation of the carboxy group of 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid with the secondary amino group of 1'-methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidine]. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo.
SB236057
SUMATRIPTAN SUCCINATE
TFMPP
[11C]AZ10419369
[3H]ELETRIPTAN
[3H]GR 125,743
[3H]N-METHYL-AZ10419369
[3H]SUMATRIPTAN
&ALPHA;-METHYL-5-HT
CHEMBL:CHEMBL490417
DIMETHYLTRYPTAMINE
FENFLURAMINE HYDROCHLORIDE
LYSERGIC ACID An ergoline alkaloid comprising 6-methylergoline having additional unsaturation at the 9,10-position and a carboxy group at the 8-position.
TONABERSAT
[3H]5-CT
[3H]5-HT
5-BODMT
5-FLUOROTRYPTAMINE
BRL-54443
DOI
LASMIDITAN
LASMIDITAN SUCCINATE
(+)-DOI
(+)-LSD
(R)-70 [PMID: 36171289]
(R)-DOI
4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE
AC-90179
AGOMELATINE
AL-37350A
AMESERGIDE
ARIPIPRAZOLE A quinolone that has formula C23H27Cl2N3O2.
BF-1
BROLAMFETAMINE
COMPOUND 3B [PMID:28943244]
EGIS-7625
EPLIVANSERIN
EPLIVANSERIN FUMARATE
GLEMANSERIN
H05
IFERANSERIN
LEVOMILNACIPRAN
LORCASERIN
LY063518
LY215840
LY314228
LY320954
LY53857
LY86057
MESCALINE A phenethylamine alkaloid that is phenethylamine substituted at positions 3, 4 and 5 by methoxy groups.
MESULERGINE A member of the class of ergot alkaloids that is known to act on serotonin and dopamine receptors.
N-1-ISOPROPYL-5-MEOT
N-1-ISOPROPYLTRYPTAMINE
NELOTANSERIN
NEMIFITIDE
ORG 12962
ORG-37684
PIMAVANSERIN
PIMAVANSERIN TARTRATE
PRUVANSERIN
PSILOCIN
PSILOCYBINE
RELENOPRIDE
RENZAPRIDE
RO 60-0175
ROLUPERIDONE
RS-102221
RS-127445
SB 221284 An indolyl carboxylic acid that has formula C16H14F3N3OS.
SB 243213 An indolyl carboxylic acid that has formula C22H19F3N4O2.
SDZ SER-082
SERGOLEXOLE
TEMANOGREL
VABICASERIN HYDROCHLORIDE
VOLINANSERIN
[11C]GSK215083
[11C]VOLINANSERIN
[18F]ALTANSERIN
(-)-NORFENFLURAMINE
ATC0175
DIHYDROERGOCRYPTINE
NORFENFLURAMINE
NORFLUOXETINE
PIBOSEROD
PRX-08066
TEGASEROD
VABICASERIN
[125I]DOI
[3H]LSD
[3H]MESULERGINE
ATHX-105
FR260010
IDALOPIRDINE
LORCASERIN HYDROCHLORIDE
LY334362
WAY-163909
YM348
ALOSETRON
AZASETRON
BIMU 1
CILANSETRON
DDP-225
DOLASETRON
DOLASETRON MESYLATE
GRANISETRON HYDROCHLORIDE
ITASETRON
LERISETRON
LINTOPRIDE
LITOXETINE
MOSAPRIDE
OCTOPAMINE Octopamine is a biogenic phenylethanolamine, which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.
PANCOPRIDE
PROCAINE A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
PUMOSETRAG
RAMOSETRON
RAMOSETRON HYDROCHLORIDE
ZATOSETRON MALEATE
APREPITANT
BIMU 8
CHEMBL:CHEMBL401607
CISAPRIDE The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
CISAPRIDE MONOHYDRATE
DA-6886
DAU 6285
GR 125487
ML 10375
NARONAPRIDE
PF-04995274
PRUCALOPRIDE
PRUCALOPRIDE SUCCINATE
PRX-03140
REVEXEPRIDE
RS 100235
RS 67333
SB 207710
TD-2749
TD-8954
USMARAPRIDE
VELUSETRAG
ZACOPRIDE
[11C]SB207145
[3H]GR 113808
SB 699551
[125I]LSD
CERLAPIRDINE
E6801
EMD-386088
FLUPERLAPINE A benzazepine that has formula C19H20FN3.
ICI 169369
INTEPIRDINE
LANDIPIRDINE
MARITUPIRDINE
MASUPIRDINE
PF-05212377
PRX-07034
RO 63-0563
SB 271046
SB258585
SB357134
SB399885
SUVN-502
WAY-181187
WAY-208466
[125I]SB258585
2-BROMO-LSD
AS-19
CIMIPRONIDINE
DR-4004
E55888
FUKINOLIC ACID
JNJ-18038683
LY2590443
SB 258719
SB656104
GALEGENIMAB
CALYCULIN A A monoterpenoid that has formula C50H81N4O15P.
CHEMBL:CHEMBL258316
CHEMBL:CHEMBL526034
CHEMBL:CHEMBL577419
CHEMBL:CHEMBL579957
CHEMBL:CHEMBL580609
CHEMBL:CHEMBL582030
CHEMBL:CHEMBL582073
CHEMBL:CHEMBL598903
CHEMBL:CHEMBL602987
FLUORESCEIN DIACETATE
FUCHSIN, BASIC
LAURYL ISOQUINOLINIUM
MECETRONIUM
MIRIPIRIUM
NITROVIN
RAFOXANIDE
TRYPAN BLUE FREE ACID
HSL119
ALICAFORSEN
ENLIMOMAB
ENLIMOMAB PEGOL
LIFITEGRAST
ICM3
FELADILIMAB
MEDI-570
ROZIBAFUSP ALFA
VOPRATELIMAB
AMG-557
BACITRACIN A mixture of at least nine closely related homodetic cyclic peptides produced by Bacillus subtilis and B. licheniformis, which is particularly active against Gram-positive bacteria.
BIOTIN An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins.
NTE-1
NTE-2
QUINOLINE 2
2,4-DIACETYLPHLOROGLUCINOL
9-AMINOCAMPTOTHECIN
ANISOCOUMARIN H
BAY1436032
CENTAUREIDIN
CHALCONE A member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group.
CHEMBL:CHEMBL121556
CHEMBL:CHEMBL1257013
CHEMBL:CHEMBL1257031
CHEMBL:CHEMBL1420457
CHEMBL:CHEMBL1431017
CHEMBL:CHEMBL1529479
CHEMBL:CHEMBL1873045
CHEMBL:CHEMBL268584
CHEMBL:CHEMBL353764
CHEMBL:CHEMBL405317
CHEMBL:CHEMBL426
CHEMBL:CHEMBL528647
CHEMBL:CHEMBL530682
CHEMBL:CHEMBL532909
CHEMBL:CHEMBL535307
CHEMBL:CHEMBL548458
CHEMBL:CHEMBL579640
CHEMBL:CHEMBL580918
CHEMBL:CHEMBL581257
CHEMBL:CHEMBL582055
CHEMBL:CHEMBL583584
CHEMBL:CHEMBL587579
CHEMBL:CHEMBL589238
CHEMBL:CHEMBL591178
CHEMBL:CHEMBL598263
CHEMBL:CHEMBL598883
CHEMBL:CHEMBL599102
CHEMBL:CHEMBL600773
CHEMBL:CHEMBL602209
CHEMBL:CHEMBL609027
CHEMBL:CHEMBL610622
CHEMBL:CHEMBL74644
CINOBUFOTALIN A steroid lactone that has formula C26H34O7.
DIGOXIGENIN A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.
DOLASTATIN 12
DS-1001B
ENASIDENIB MESYLATE
IDH305
IVOSIDENIB
KINETIN RIBOSIDE
LESCOL
LEVOMEPROMAZINE MALEATE
LOPERAMIDE HYDROCHLORIDE
LY3410738
LYNGBYABELLIN A
N-ACETYLCOLCHINOL
NEOCUPROINE
OLUTASIDENIB
PERUVOSIDE
PREGNENOLONE SULFATE SODIUM
PROTRIPTYLINE HYDROCHLORIDE
RANOSIDENIB
SAFUSIDENIB
TENONITROZOLE
VORASIDENIB
VORASIDENIB CITRATE
WR-159412
CHEMBL:CHEMBL3392845
IDH2 MUTANT INHIBITOR SH1573
IDH2 MUTANT INHIBITOR TQB3455
1-METHYL-L-TRYPTOPHAN
AMG-1
CHEMBL:CHEMBL1224312
CHEMBL:CHEMBL14145
CHEMBL:CHEMBL1668301
CHEMBL:CHEMBL1933308
COMPOUND 8U [PMID: 31999451]
EPACADOSTAT
IDO-1 INHIBITOR LY3381916
INDOXIMOD PRODRUG NLG802
KHK2455
LINRODOSTAT
LW106
PF-06840003
PHENYLHYDRAZINE A phenylhydrazine that is the monophenyl derivative of hydrazine.
TRYPTANTHRIN 5I
EXAMPLE 184 [WO2014186035]
IDURSULFASE
CL 246738
CORYNEBACTERIUM GRANULOSUM P40
FARALIMOMAB
RONTALIZUMAB
SIFALIMUMAB
ALBINTERFERON ALFA-2B
INTERFERON ALFA-N3
NADOFARAGENE FIRADENOVEC
NOVAFERON
ROPEGINTERFERON ALFA-2B
ANIFROLUMAB
IFN-&BETA;
INTERFERON ALFA-2A
INTERFERON ALFA-N1
INTERFERON ALFACON-1
INTERFERON BETA
INTERFERON-ALPHA
PEGINTERFERON ALFACON-1
PEGINTERFERON BETA-1A
DAZUKIBART
LYOPHILIZED HUMAN RECOMBINANT INTERFERON-BETA 1A FP-1201
AMG-811
EMAPALUMAB
FONTOLIZUMAB
FUMARIC ACID A butenedioic acid in which the C=C double bond has E geometry. It is an intermediate metabolite in the citric acid cycle.
THERAPEUTIC AUTOLOGOUS LYMPHOCYTES
INTERFERON GAMMA-1B
PEGINTERFERON LAMBDA-1A
ASUNAPREVIR
DASABUVIR
DELEOBUVIR
ELBASVIR
ELBASVIR/GRAZOPREVIR
FALDAPREVIR
GRAZOPREVIR
LEDIPASVIR
OMBITASVIR
OMBITASVIR/PARITAPREVIR/RITONAVIR
PARITAPREVIR
SIMEPREVIR
SOFOSBUVIR / VELPATASVIR / VOXILAPREVIR
SOFOSBUVIR/VELPATASVIR
VELPATASVIR
VOXILAPREVIR
DUSIGITUMAB
TROFINETIDE
XENTUZUMAB
AEW-541
AG 1024
ANTI-IGF-1R RECOMBINANT MONOCLONAL ANTIBODY BIIB022
BIIB-022
CIXUTUMUMAB
DALOTUZUMAB
FIGITUMUMAB
GSK1511931
INSULIN-LIKE GROWTH FACTOR 2
KW-2450
LINSITINIB
MECASERMIN RINFABATE
PICROPODOPHYLLIN
PL-225B
PQ401
RINFABATE
ROBATUMUMAB
TEPROTUMUMAB
VELIGROTUG
MANNOSE 6-PHOSPHATE
AURANOFIN
BI605906
CHEMBL:CHEMBL256967
CHEMBL:CHEMBL401565
IKK-2 INHIBITOR IV
IKK-BETA INHIBITOR R-28
IMD-1041
IMD-2560
MLN-0415
MLN-120B
PARTHENOLIDE
R-RUGULACTONE
SAR-113945
COMPOUND 17D [PMID: 23099093]
COMPOUND II [PMID: 21329883]
GSK8612
MPI-0485520
MRT67307
SR8185
ILODECAKIN
LISOFYLLINE
PEGILODECAKIN
SCH-708980
IL-10
EFLEPEDOCOKIN ALFA
BONE METASTASIS TARGETING PEPTIDE-11
ADENOVIRAL TRANSDUCED HIL-12-EXPRESSING AUTOLOGOUS DENDRITIC CELLS INXN-3001 PLUS ACTIVATOR LIGAND INXN-1001
APILIMOD
BRIAKINUMAB
EBDAROKIMAB
EGEN-001
HUMANIZED SMART ANTI-IL-12 ANTIBODY
MIRIKIZUMAB
VIRULIZIN
BRAZIKUMAB
GUSELKUMAB
RISANKIZUMAB
ANRUKINZUMAB
CENDAKIMAB
CNTO-5825
DECTREKUMAB
LEBRIKIZUMAB
QAX-576
ROMILKIMAB
TRALOKINUMAB
EBLASAKIMAB
MULTI-GLIOBLASTOMA-PEPTIDE-TARGETING AUTOLOGOUS DENDRITIC CELL VACCINE ICT-107
IMMUNOADJUVANT
ORDESEKIMAB
ALT-803
IL-15
IL-2/9/15 GAMMA CHAIN RECEPTOR INHIBITOR BNZ-1
NOGAPENDEKIN ALFA INBAKICEPT
RECOMBINANT HUMAN INTERLEUKIN-15
ABBV-257
AFASEVIKUMAB
ANTI-IL17A MONOCLONAL ANTIBODY CJM112
BIMEKIZUMAB
BRODALUMAB
CJM-112
COVA322
IXEKIZUMAB
IZOKIBEP
M-1095
PERAKIZUMAB
REMTOLUMAB
TIBULIZUMAB
VUNAKIZUMAB
CAMOTESKIMAB
GSK-1070806
TADEKINIG ALFA
AMG-108
BERMEKIMAB
LUTIKIZUMAB
MABP1
CDP-484
CHINESE HERBS
CLODRONIC ACID
GALLIUM NITRATE
GEVOKIZUMAB
GLUCOSAMINE
PENTAMIDINE A diether compound consisting of pentane-1,5-diol with both hydroxyls bearing 4-amidinophenyl groups.
POLYVALENT VACCINE
TILUDRONIC ACID
TT-301
MEDI-8968
ASTEGOLIMAB
IMSIDOLIMAB
SPESOLIMAB
MAB92
CARBOXYAMIDOTRIAZOLE OROTATE
CEFEPIME HYDROCHLORIDE
CELL DIFFERENTIATING AGENT
DACLIZUMAB
DIDEMNIN B
ETHYLENEIMINE
GARLIC EXTRACT
HUMAN INTERLEUKIN-2
IMIPENEM ANHYDROUS
LEUVECTIN
LORUKAFUSP ALFA
MESMULOGENE ANCOVACIVEC
MISTLETOE EXTRACT
RECOMBINANT SOLUBLE HUMAN CD4 PROTEIN
RECOMBINANT TRANSFORMING GROWTH FACTOR-BETA
SIGNAL TRANSDUCTION INHIBITOR
THYMOCTONAN
FLETIKUMAB
IL-21
NNC0114-0006
DENENICOKIN
EFMARODOCOKIN ALFA
FEZAKINUMAB
ANTI-TAC 90 Y-HAT
BASILIXIMAB
CAMIDANLUMAB TESIRINE
DHA-PACLITAXEL
FARNESYLTRANSFERASE/GERANYLGERANYLTRANSFERASE INHIBITOR L-778,123
HUMAN THYMOSIN-FRACTION 5
INOLIMOMAB
INTERLEUKIN-2 GENE
LENTINAN
MONOCLONAL ANTIBODY R24
BEMPEGALDESLEUKIN
HUMIK-BETA-1
LEUKOCYTE INTERLEUKIN
MIK-BETA-1
PEGENZILEUKIN
GLYCOSYLATED RECOMBINANT HUMAN INTERLEUKIN-7
LOKIVETMAB
VIXARELIMAB
NEMOLIZUMAB
ETOKIMAB
ITEPEKIMAB
TORUDOKIMAB
ALLOGENEIC CD123-SPECIFIC UNIVERSAL CAR123-EXPRESSING T-LYMPHOCYTES
ANTI-CD123 CAR T CELLS PREPARATION
ANTI-CD123/CD3 BISPECIFIC ANTIBODY JNJ-63709178
AUTOLOGOUS CD123CAR-CD28-CD3ZETA-EGFRT-EXPRESSING T LYMPHOCYTES MB-102
CSL-360
IL-3
PIVEKIMAB SUNIRINE
PASCOLIZUMAB
BIZAXOFUSP
DUPILUMAB
MANFIDOKIMAB
PITRAKINRA
STAPOKIBART
BENRALIZUMAB
DEPEMOKIMAB
RESLIZUMAB
IL-5
BIAFINE CREAM
C326
CLAZAKIZUMAB
ELSILIMOMAB
IMIPENEM-CILASTATIN SODIUM
MRA 003 US
OLOKIZUMAB
PACIBEKITUG
SAFINGOL
SELECTIVE ESTROGEN RECEPTOR MODULATOR
SILTUXIMAB
SIRUKUMAB
VITAMIN A PALMITATE
YSIL6
IL-6
LEVILIMAB
SARILUMAB
VOBARILIZUMAB
GSK2618960
HIV VACCINE
BEMPIKIBART
LUSVERTIKIMAB
ENOKIZUMAB
COMPOUND 22 [PMID: 21823616]
AVN-944
MERIMEPODIB
MYCOPHENOLATE MOFETIL HYDROCHLORIDE
MYCOPHENOLATE SODIUM
TARIBAVIRIN HYDROCHLORIDE
TIAZOFURIN
VX-148
CHEMBL:CHEMBL1683024
ETHIONAMIDE A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2.
GARETOSMAB
STM 434
COMPOUND 5 [NOBLE ET AL., 1992]
3 ALPHA-AMINOCHOLESTANE
ROSIPTOR
TURNAGAINOLIDE B
AS1949490
INSULIN DEGLUDEC
INSULIN PEGLISPRO
INSULIN SUSP ISOPHANE RECOMBINANT HUMAN
INSULIN ZINC SUSP RECOMBINANT HUMAN
INULIN
AGT-182
INSULIN ASPART PROTAMINE RECOMBINANT
INSULIN ASPART PROTAMINE, HUMAN
INSULIN DETEMIR
INSULIN GLARGINE
INSULIN GLULISINE, HUMAN
INSULIN HUMAN
INSULIN HUMAN ZINC
INSULIN HUMAN, ISOPHANE
INSULIN ICODEC
INSULIN LISPRO
INSULIN LISPRO PROTAMINE RECOMBINANT
INSULIN PORK
INSULIN PURIFIED BEEF
INSULIN PURIFIED PORK
INSULIN SENSITIZER S-707106
INSULIN SUSP ISOPHANE BEEF
INSULIN SUSP ISOPHANE SEMISYNTHETIC PURIFIED HUMAN
INSULIN TREGOPIL
INSULIN ZINC, EXTENDED
INSULIN ZINC, PROMPT
INSULIN [INJECTION], BIPHASIC
INSULIN, ISOPHANE
INSULIN, NEUTRAL
INSULIN, PORCINE
INSULIN, PROTAMINE ZINC
METFORMIN GLYCINATE
MITOGLITAZONE
RECOMBINANT HUMAN KALLIKREIN-1
TESOFENSINE
BMS-707035
COMPOUND 1 [WO2012007375]
COMPOUND 7 [WO2012007375]
IRAK-1/4 INHIBITOR
NACRESERTIB
COMPOUND R-16 [PMID: 21967808]
IRAK3 PROTAC 23
BAY1830839
BIO-7488
BIO-8169
EDECESERTIB
EMAVUSERTIB
GLPG2534
IRAK4 INHIBITOR 4B [PMID: 18474425]
IRAK4 INHIBITOR RAC-45 [PMID: 18501603]
ND-2110
ND-2158
PF-06426779
ZABEDOSERTIB
ZIMLOVISERTIB
ZOMIRADOMIDE
AGANIRSEN
SAN-300
VATELIZUMAB
ENOXAPARIN
GANTOFIBAN
TADOCIZUMAB
TIROFIBAN HYDROCHLORIDE
ZALUNFIBAN
PEPTIDE LIGAND 2 [PMID: 19055415]
ABRILUMAB
ATL1102
BIO1211
CAROTEGRAST
CAROTEGRAST METHYL
FIRATEGRAST
NATALIZUMAB
R1295
SENKTIDE
UCB-1184197
VALATEGRAST
VEDOLIZUMAB
ZAURATEGRAST
ATN-161
ETARACIZUMAB
INTEGRIN RECEPTOR ANTAGONIST GLPG0187
JSM 6427
PF-04605412
VOLOCIXIMAB
BOP
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1|
BI-1950
BIRT 377
CASEARINOL B
CASEARINONE A
CASEARINONE B
EFALIZUMAB
ODULIMOMAB
RESINIFERATOXIN A diterpenoid that has formula C37H40O9.
ROVELIZUMAB
ABITUZUMAB
BEXOTEGRAST
CYPATE
GSK3008348
IMGN-388
INTETUMUMAB
MK-0429
RG-7594
STX-100
COMPOUND 7 [PMID: 31381331]
BUTEIN A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.
ERLIZUMAB
MLN-01
MLNM-2201
RECOMBINANT HUMAN THROMBOPOIETIN
SIGVOTATUG
SIGVOTATUG VEDOTIN
ETROLIZUMAB
BMS-509744
CHEMBL:CHEMBL2179805
COMPOUND 4G [PMID: 21316219]
COMPOUND 7 [PMID: 22464456]
GNE-4997
MODZATINIB
SOQUELITINIB
GNF362
ADENOPHOSTIN A A disaccharide phosphate that has formula C16H26N5O18P3.
DECAVANADATE
INOSITOL 2,4,5-TRISPHOSPHATE
IP3
PIP2
XESTOSPONGIN C
RETINYL ACETATE
BLOVACITINIB
BMS-911543
BREPOCITINIB
CEE321
COMPOUND 19A [PMID: 24359159]
COMPOUND 8L [PMID: 36053746]
DECERNOTINIB
DELGOCITINIB
DEURUXOLITINIB PHOSPHATE
FILGOTINIB MALEATE
GDC-0214
GIROCITINIB
GLPG-0555
GOLIDOCITINIB
GUSACITINIB
ILGINATINIB
INCB-047986
ITACITINIB
IVARMACITINIB
IZENCITINIB
JAK INHIBITOR 17B
JAK INHIBITOR 20A
JAK3 INHIBITOR 32
JAK3 INHIBITOR 34
JAK3 INHIBITOR IV
LASW1393
LEPZACITINIB
LIRUCITINIB
LONDAMOCITINIB
LORPUCITINIB
NEZULCITINIB
OCLACITINIB
PEFICITINIB
PF-06263276
PF-956980
POVORCITINIB
ROPSACITINIB
RUXOLITINIB PHOSPHATE
SAR-20347
SDC-1801
SJ988497
SOLCITINIB
TOFACITINIB CITRATE
TRICETAMIDE
UPADACITINIB HEMIHYDRATE
VEXICITINIB
WXFL10203614
XL019
ZEMPROCITINIB
A-1155463
AC-430
AC430
AG 1296
AZ960
CEP-33779
COMPOUND 11 [PMID: 35653642]
COMPOUND 13 [PMID: 35653642]
EMZELTRECTINIB
GANDOTINIB
HG-10-102-01
JAK2V617F INHIBITOR INCB160058
LS-104
NS-018
PIM KINASE INHIBITOR LGH447
ROVADICITINIB
SAFIMALTIB
SOFICITINIB
TENALISIB
TYK2 INHIBITOR 14L
UZANSERTIB
XL-019
R-333
R-348
TASOCITINIB
WHI-P131
(-)-CAMPHOR
2-MERCAPTOPYRIMIDINE
BRUCEANTIN
BUTINOLINE
CARBOXYMETHYL-TRIMETHYL-ARSONIUM
CHEMBL:CHEMBL477052
CIPROFIBRATE
COPPER CHLORIDE
HOLACANTHONE
IRISOLIDONE
NEOCHAMAEJASMIN A
RETINYLRETINOATE
SERGEOLIDE
SODIUM SELENITE
T-5224
8-HYDROXY-7-IODO-5-QUINOLINESULFONIC ACID
AC55649
ANAZOLENE
CHLORISONDAMINE
CHLORPYRIFOS-METHYL An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
CIGLITAZONE An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
ERUCIC ACID A docosenoic acid having a cis- double bond at C-13. It is found particularly in brassicas - it is a major component of mustard and rapeseed oils and is produced by broccoli, Brussels sprouts, kale, and wallflowers.
FRAXINE
HYPERFORIN A sesquarterpenoid that has formula C35H52O4.
IOPHENOXIC ACID