GAD High Level Gene-Disease Associations Dataset

Description gene-disease associations curated from genetic association studies
Measurement genetic association by data aggregation from genome-wide association and other genetic association studies
Association gene-disease associations curated from genetic association studies
Category disease or phenotype associations
Resource Genetic Association Database
Citation(s)
Last Updated 2015 Apr 06
Stats
  1. 8013 genes
  2. 18 diseases
  3. 28182 gene-disease associations

Data Access

API
Script

Visualizations

  • Attribute Similarity

  • Gene Attribute

  • Gene Similarity

disease Gene Sets

18 sets of genes associated with diseases in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.

Gene Set Description
aging A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
cancer A malignant neoplasm in which new abnormal tissue grow by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
cardiovascular
chemdependency
developmental
hematological
immune
infection The state of being infected such as from the introduction of a foreign agent such as serum, vaccine, antigenic substance or organism.
metabolic
mitochondrial A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy).
neurological
normalvariation
other
pharmacogenomic
psych
renal
reproduction The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
vision