4492 sets of genes associated with phenotypes in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
| Gene Set |
Description |
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Lymphocyte percentage of white cells
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Erythrocyte methylated 6-mercaptopurine metabolite concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia
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DNA-incorporated thioguanine levels in 6-mercaptopurine-treated acute lymphoblastic leukaemia
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Erythrocyte thioguanine concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia
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Mean corpuscular hemoglobin
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The MCH is the average mass of hemoglobin per red blood cell in a sample of blood and is calculated by dividing the total mass of hemoglobin by the RBC count
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Modic changes
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Meconium ileus in cystic fibrosis
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Chronic obstructive pulmonary disease
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A group of disorders affecting the bronchi and the lung parenchyma. It is characterized by chronic and irreversible obstruction of the airflow. It includes chronic bronchitis and pulmonary emphysema.|A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.|A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.
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Mean corpuscular hemoglobin concentration
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The mean corpuscular gemoglobin concentration is a measure of the concentration of hemoglobin in a given volume of packed red blood cell
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Lung function (FVC)
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High light scatter reticulocyte count
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Nicotine dependence symptom count
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High light scatter reticulocyte percentage of red cells
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Lymphocyte count
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A quantification of lymphocytes in blood.
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Basophil count
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Mean corpuscular volume
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A mean corpuscular volume is the result of calculation of the mean volume of erythrocytes in a blood sample.
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Monocyte count
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quantification of monocytes in the blood
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Mean platelet volume
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A measurement of mean platelet volume is a machine-calculated measurement of the average size of platelets found in blood
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Platelet count
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The number of PLATELETS per unit volume in a sample of venous BLOOD.
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Red blood cell count
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Breast cancer (estrogen-receptor positive)
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Breast cancer (progesterone-receptor positive)
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Alzheimer's disease or fasting glucose levels (pleiotropy)
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Alzheimer's disease or fasting insulin levels (pleiotropy)
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Alzheimer's disease or HDL levels (pleiotropy)
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Thiopurine-induced myelosuppression in inflammatory bowel disease
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FEV1
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Lung function (FEV1/FVC)
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Attention deficit hyperactivity disorder or intracranial volume (pleiotropy)
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Attention deficit hyperactivity disorder or putamen volume (pleiotropy)
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Ocular sarcoidosis
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Ocular sarcoidosis in sarcoidosis
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Autism spectrum disorder
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A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.
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Alzheimer's disease (late onset)
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disease cluster belonging to disease group neurological
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Opioid exposure
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Nicotine metabolite ratio in current smokers
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Aortic valve stenosis
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An aortic valve disease that has_physical_basis_in incomplete opening of the aortic valve.
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Hemoglobin
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Conjunctival UV autofluorescence (CUVAF)
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Immature fraction of reticulocytes
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Behcet's disease
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A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.
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Pelvic organ prolapse
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Abnormal descent of a pelvic organ resulting in the protrusion of the organ beyond its normal anatomical confines.
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Serum metabolite levels
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Coronary artery disease
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Thickening and loss of elasticity of the CORONARY ARTERIES, leading to progressive arterial insufficiency (CORONARY DISEASE).|Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.|Narrowing of the coronary arteries due to fatty deposits inside the arterial walls.|An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
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Platelet distribution width
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Gut microbiota (bacterial taxa, hurdle binary method)
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Autoimmune thyroid disease
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disease cluster belonging to disease group immune
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Attention deficit hyperactivity disorder (inattention symptoms)
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Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms)
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Attention deficit hyperactivity disorder
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A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-IV)
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Reticulocyte count
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Reticulocyte fraction of red cells
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Red cell distribution width
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CV-A6-associated hand, foot, and mouth disease (severe vs mild)
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Breast cancer
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A thoracic cancer that originates in the mammary gland.
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White blood cell count
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Estrogen level change in anastrozole-treated breast cancer
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Nonalcoholic fatty liver disease
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Rheumatic heart disease
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A heart valve disease that is characterized by repeated inflammation with fibrinous repair. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.It is caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage.
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Cardiovascular death or myocardial infarction in response to clopidogrel treatment
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Platelet reactivity in response to clopidogrel treatment
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Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment
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Stent thrombosis in response to clopidogrel treatment
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Diastolic blood pressure
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Systolic blood pressure
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Receptive language ability
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Parent of origin effect on receptive language ability (paternal)
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Thrombin-induced platelet aggregation
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Acute anterior uveitis in ankylosing spondylitis
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Asthma
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A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways.|Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.|A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).|A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, excercise, stress, reflux disease, medications, foods and emotional anxiety.
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Body mass index
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An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
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Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis)
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Interleukin-6 levels
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Stroke
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A sudden, nonconvulsive loss of neurologic function due to an ischemic or hemorrhagic intracranial vascular event. In general, cerebrovascular accidents are classified by anatomic location in the brain, vascular distribution, etiology, age of the affected individual, and hemorrhagic vs. nonhemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)|A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)|A sudden, nonconvulsive loss of neurologic function due to an ischemic or hemorrhagic intracranial vascular event. In general, cerebrovascular accidents are classified by anatomic location in the brain, vascular distribution, etiology, age of the affected individual, and hemorrhagic vs. nonhemorrhagic nature (MeSH).|A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event.|Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
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Lung adenocarcinoma (survival time) in never smokers
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Nontraumatic osteonecrosis of the femoral head
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Parkinson's disease progression (motor)
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Parkinson's disease progression (cognitive)
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Parkinson's disease progression (composite)
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Diabetic neuropathy in type 2 diabetes
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Macrovascular complications in type 2 diabetes
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Ophthalmic complications in type 2 diabetes
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Fasting plasma glucose
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Tau burden
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PR interval
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A PR interval is an electrocardiography measurement which measures from the beginning of the P wave to the beginning of the QRS complex in the heart's electrical cycle
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Prostate cancer
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A male reproductive organ cancer that is located_in the prostate.
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Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia
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prednisolone sensitivity in B-cell precursor acute lymphoblastic leukaemia
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dexamethasone sensitivity in B-cell precursor acute lymphoblastic leukaemia
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Serum C-reactive protein concentration
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Serum C-reactive protein concentration in non-obese individuals
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Serum C-reactive protein concentration in obesity
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Serum C-reactive protein concentration in low fat diet
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Serum C-reactive protein concentration in high fat diet
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Serum C-reactive protein concentration in visceral obesity (waist-hip ratio)
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Serum C-reactive protein concentration in visceral obesity (waist circumference)
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Serum interleukin-6 concentration in active individuals
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Neonatal white matter microstructure
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Restless legs syndrome in migraine without aura
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Restless legs syndrome in migraine
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Concussion
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High myopia
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Cerebrospinal fluid t-tau:AB1-42 ratio
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Long QT syndrome
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An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles).
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Leprosy
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A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
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Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism
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Serum uric acid levels
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Dietary fat liking
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Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer
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Clozapine concentration in schizophrenia
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N-desmethylclozapine concentration in schizophrenia
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Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia
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Gestational insulin sensitivity
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Mean reticulocyte volume
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LDL cholesterol levels
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HDL cholesterol levels
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disease cluster belonging to disease group cardiovascular
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Total cholesterol levels
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Total triglycerides levels
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Mean spheric corpuscular volume
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Neutrophil percentage of white cells
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Obese vs. thin
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Obesity (extreme)
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disease cluster belonging to disease group metabolic
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Normal body mass index vs. thin
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Plateletcrit
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Essential hypertension (time to event)
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Hyperlipidemia (time to event)
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Osteoarthrosis (time to event)
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Asthma (time to event)
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Coronary atherosclerosis (time to event)
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Multiple myeloma
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A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)|A myeloma that is located_in the plasma cells in bone marrow.|A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
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Central corneal thickness
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A measure of the corneal thickness (CCT). This can be measured by contact e.g. ultrasound, confocal microscpy or non contact methods e.g. biometry. Reduced central corneal thickness is used as an indicator for glaucoma.
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Type 2 diabetes (time to event)
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Carotid intima media thickness x smoking interaction
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Adverse response to inhaled corticosteroid treatment x age interaction in asthma
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Creativity
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Left ventricular end-diastolic volume
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Left ventricular end-systolic volume
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Left ventricular ejection fraction
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Emotional recognition
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Neutrophil count
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Is a quantification of neutrophils in blood.
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Weight gain in amisulpride-treated first-episode psychosis
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Polycystic ovary syndrome
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A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
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Adult diffuse glioma (IDH mutation)
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Adult diffuse glioma (IDH wildtype)
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Adult diffuse glioma (IDH mutation, 1p/19q non-codeleted)
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Adult diffuse glioma (TERT mutation only)
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Anthracycline-induced cardiotoxicity in early breast cancer
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Drug-induced liver injury (flucloxacillin)
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disease cluster belonging to disease group pharmacogenomic
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Glycated hemoglobin levels in type 1 diabetes
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Crohn's disease
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An intestinal disease that involves inflammation located_in intestine.
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Spontaneous coronary artery dissection
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Sweet taste preference
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Urine 6-bromotryptophan levels in chronic kidney disease
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Bladder cancer
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Endometriosis or migraine
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Venous thromboembolism
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Obstruction of a vein or VEINS (embolism) by a blood clot ( THROMBUS) in the blood stream.
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Systolic blood pressure x educational attainment (some college) interaction (2df)
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Systolic blood pressure x educational attainment (graduated college) interaction (2df)
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Diastolic blood pressure x educational attainment (graduated college) interaction (2df)
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Mean arterial pressure x educational attainment (some college) interaction (2df)
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Mean arterial pressure x educational attainment (graduated college) interaction (2df)
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Pulse pressure x educational attainment (some college) interaction (2df)
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Postoperative myocardial infarction after cardiac surgery
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Postoperative stroke after cardiac surgery
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Postoperative acute renal failure after cardiac surgery
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Postoperative atrial fibrillation after cardiac surgery
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Postoperative complication after cardiac surgery
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Peak expiratory flow
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Arsenic metabolism
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disease cluster belonging to disease group pharmacogenomic
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Monocyte percentage of white cells
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Intracranial aneurysm
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Tourette syndrome
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Estimated glomerular filtration rate in coronary artery disease and impaired kidney function
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Crohn's disease or systemic sclerosis
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Calcific aortic valve stenosis
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A type of aortic valve stenosis associated with calcification of the aortic heart valve.
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Thyroid volume in Hashimoto’s thyroiditis
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Insomnia symptoms (never/rarely vs. usually)
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Insomnia symptoms (never/rarely vs. sometimes/usually)
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IgG N-glycosylation phenotypes (multivariate analysis)
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Thyroxine levels
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Triiodothyronine levels
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Triiodothyronine/thyroxine ratio
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Serum urea levels
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Gut microbiota (bacterial taxa, rank normal transformation method)
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Polycystic ovary syndrome (reproductive subtype)
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Polycystic ovary syndrome (metabolic subtype)
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Polycystic ovary syndrome (indeterminate subtype)
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Sepsis (hospital admission)
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Pneumonia (28-day mortality)
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Sepsis (28-day mortality)
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Sepsis (90-day mortality)
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Benign childhood epilepsy with centro-temporal spikes
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Cardiorespiratory fitness (800m run time)
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Cognitive impairment in depression
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First year height change in growth hormone-treated short stature
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Type 2 diabetes
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disease cluster belonging to disease group metabolic
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Chronic rhinosinusitis
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Nasal polyps
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Chronotype (sMEQ score)
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Evening vs. morning chronotype (sMEQ score)
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Evening vs. morning chronotype (self-assessed)
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Depressive symptoms x herpes simplex 1 infection interaction
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Depression x herpes simplex 1 infection interaction
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Response to antiepileptic mood-stabilizing treatment in bipolar disorder
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Autism spectrum disorders (social interaction)
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L-selectin levels
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White matter hyperintensity volume x hypertension interaction (2df)
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Triglyceride levels in HIV infection
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White matter hyperintensity volume (adjusted for hypertension)
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LDL cholesterol levels in HIV infection
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White matter hyperintensity volume
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HDL cholesterol levels in HIV infection
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Parental lifespan
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Homeostasis model assessment of insulin resistance
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Fasting glucose
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disease cluster belonging to disease group metabolic
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Plasma selenium concentration
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Response to selenium supplementation (change in plasma selenium concentration)
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Caffeine consumption from coffee or tea
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Caffeine consumption from coffee
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Caffeine consumption from tea
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Problematic alcohol use
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Leg fat mass (lean adjusted)
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Leg lean mass (fat adjusted)
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Leg fat mass and leg lean mass (pleiotropy)
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Tumor necrosis factor levels
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Vaginal microbiome composition (L. iners)
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Vaginal microbiome composition (G. vaginalis)
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Vaginal microbiome composition (Shannon diversity index)
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Vaginal microbiome composition (community state type)
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Vaginal microbiome composition (L. crispatus)
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Arterial stiffness (carotid-femoral pulse wave velocity)
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Arterial stiffness (brachial-femoral pulse wave velocity)
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Arterial stiffness (brachial-ankle pulse wave velocity)
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Pancreatic beta-cell glucose sensitivity
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Sarcoidosis
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A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.
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circulating leptin levels
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circulating leptin levels adjusted for BMI
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Nonalcoholic steatohepatitis
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Distal/Left-sided colorectal cancer
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Proximal colorectal cancer
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Distal colorectal cancer
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Rectal cancer
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Colon cancer
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A colorectal cancer that is located_in the colon.
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Severe COVID-19 infection with respiratory failure (analysis I)
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Severe COVID-19 infection with respiratory failure (analysis II)
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Liver fat content (MRI proton density fat fraction measure)
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Liver fibrosis and steatohepatitis severity (MRI cT1 measure)
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Cutaneous mastocytosis
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Systemic mastocytosis
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Cutaneous mastocytosis (adult)
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Mastocytosis
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OMIM mapping confirmed by DO. [LS].
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Cutaneous mastocytosis (childhood)
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Hepatocyte growth factor levels
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Septic shock (28-day mortality)
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Septic shock resolution
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Height
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Total carotid plaque area (excess vs minimal atherosclerosis)
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Early-onset ischemic stroke
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Periventricular white matter hyperintensities
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Neuroblastoma (pediatric)
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Allergic disease (asthma, hay fever and/or eczema) (age of onset)
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Electrocardiographic traits (multivariate)
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Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis)
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Brain morphology (MOSTest)
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Cortical thickness (MOSTest)
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Subcortical volume (MOSTest)
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Brain morphology (min-P)
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Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis)
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Cortical surface area (min-P)
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Cortical thickness (min-P)
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Subcortical volume (min-P)
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Deep white matter hyperintensities
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Atopic dermatitis
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A dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.
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Fasting triglyceride levels
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Postprandial triglyceride levels
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Postprandial triglyceride response
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Leukoderma in response to rhododendrol
|
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Brugada syndrome
|
A heart conduction disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death.
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Chronic kidney disease x type 2 diabetes interaction
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Peripheral arterial disease x type 2 diabetes interaction
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Coronary heart disease x type 2 diabetes interaction
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Acute ischemic stroke x type 2 diabetes interaction
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Retinopathy x type 2 diabetes interaction
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Neuropathy x type 2 diabetes interaction
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Pancreatic cancer
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An endocrine gland cancer located_in the pancreas.
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Cortical surface area (MOSTest)
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Hypertension
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Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
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Motor fluctuations in levodopa treated Parkinson's disease
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Levodopa-induced dyskinesia in levodopa treated Parkinson's disease
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Corneal hysteresis
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Corneal resistance factor
|
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Response to esketamine in treatment resistant depression
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Response to esketamine (responder status) in treatment resistant depression
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spontaneous preterm birth x maternal stress interaction (1df)
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Ceramide levels (C24:0)
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Ceramide levels (C22:0)
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Trigger finger
|
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Rheumatoid arthritis
|
An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.
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|
Age-related macular degeneration
|
Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.|Degenerative changes in the macula lutea of the retina.
|
|
Fractures (paediatric)
|
|
|
Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG levels
|
|
|
Persistent chemotherapy-induced alopecia in breast cancer
|
|
|
Sudden cardiac arrest in coronary artery disease
|
|
|
Oral cavity cancer
|
A gastrointestinal system cancer that is located_in the oral cavity.
|
|
Oropharynx cancer
|
A pharynx cancer that is located_in the oropharynx.
|
|
Hypopharyngeal or laryngeal cancer
|
|
|
Head and neck squamous cell carcinoma
|
A squamous cell carcinoma that arises from any of the following anatomic sites: lip and oral cavity, nasal cavity, paranasal sinuses, pharynx, larynx, and salivary glands.|A carcinoma of any tissue within the head and neck region.
|
|
Male-pattern baldness
|
disease cluster belonging to disease group other
|
|
Self-rated health
|
|
|
Glaucoma (primary open-angle)
|
|
|
Household income
|
|
|
Length of menstrual cycle
|
|
|
Simvastatin-induced myopathy
|
|
|
Atorvastatin-induced myopathy
|
|
|
Statin-induced myopathy (severe)
|
|
|
Statin-induced myopathy
|
|
|
Anorectal malformation
|
|
|
Bipolar disorder
|
A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.|A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence (MeSH).
|
|
Interstitial lung diseases in rheumatoid arthritis
|
|
|
Iron status biomarkers (total iron binding capacity)
|
|
|
Iron status biomarkers (iron levels)
|
|
|
Iron status biomarkers (transferrin saturation)
|
|
|
Iron status biomarkers (ferritin levels)
|
|
|
Chemerin levels
|
|
|
First fracture in long-term childhood cancer survivors (time to event)
|
|
|
Myocardial infarction
|
Xref MGI.
|
|
Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder
|
|
|
Bipolar disorder or attention deficit hyperactivity disorder
|
|
|
Granulocyte percentage of myeloid white cells
|
|
|
Granulocyte count
|
|
|
Systemic lupus erythematosus
|
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
|
|
Systemic juvenile idiopathic arthritis
|
disease cluster belonging to disease group immune
|
|
Posterior cortical atrophy and Alzheimer's disease
|
|
|
Eosinophil percentage of white cells
|
|
|
Endometrial cancer
|
A uterine cancer that is located_in tissues lining the uterus.
|
|
Arthritis (juvenile idiopathic)
|
disease cluster belonging to disease group immune
|
|
Mathematical ability
|
|
|
C-reactive protein levels or HDL-cholesterol levels (pleiotropy)
|
|
|
C-reactive protein levels or triglyceride levels (pleiotropy)
|
|
|
C-reactive protein levels or LDL-cholesterol levels (pleiotropy)
|
|
|
Number of children ever born
|
|
|
Age at first birth
|
|
|
C-reactive protein levels or total cholesterol levels (pleiotropy)
|
|
|
Cancer (pleiotropy)
|
|
|
Cancer
|
A malignant neoplasm in which new abnormal tissue grow by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
|
|
Response to selective serotonin reuptake inhibitors in depression
|
|
|
Response to bupropion and depression
|
|
|
Response to citalopram or escitalopram in depression
|
|
|
Response to selective serotonin reuptake inhibitors and depression
|
|
|
Response to antidepressants in depression
|
|
|
Non-response to citalopram or escitalopram and depression
|
|
|
Response to citalopram or escitalopram and depression
|
|
|
Non-response to antidepressants and depression
|
|
|
Non-response to selective serotonin reuptake inhibitors and depression
|
|
|
Non-response to bupropion and depression
|
|
|
Response to antidepressants and depression
|
|
|
Response to bupropion in depression
|
|
|
Core binding factor acute myeloid leukemia
|
|
|
Eosinophil count
|
|
|
Sum neutrophil eosinophil counts
|
|
|
Cerebrospinal fluid AB1-42 levels
|
|
|
Cerebrospinal P-tau181p levels
|
|
|
Cerebrospinal T-tau levels
|
|
|
Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio)
|
|
|
Nonsyndromic cleft lip with cleft palate
|
|
|
Neutrophil percentage of granulocytes
|
|
|
Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level)
|
|
|
Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level)
|
|
|
Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level)
|
|
|
Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level)
|
|
|
Bone mineral density (femoral neck)
|
|
|
Bone mineral density (total hip)
|
|
|
Bone mineral density (spine)
|
disease cluster belonging to disease group metabolic
|
|
Hematocrit
|
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
|
|
Macular telangiectasia type 2
|
|
|
Monocyte-lymphocyte ratio
|
|
|
Abdominal aortic aneurysm
|
An aortic aneurysm that is located_in the abdominal aorta.
|
|
Response to carboplatin in ovarian cancer (MTT IC50)
|
|
|
Response to carboplatin and paclitaxel in ovarian cancer (Caspase 3/7 EC50)
|
|
|
Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50)
|
|
|
Response to paclitaxel in ovarian cancer (MTT IC50)
|
|
|
Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50)
|
|
|
Gout
|
Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.
|
|
Renal underexcretion gout
|
|
|
Renal overload gout
|
|
|
Erythrocyte cadmium concentration
|
|
|
Erythrocyte cadmium concentration in never smokers
|
|
|
Heroin dependence
|
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
|
|
Sum basophil neutrophil counts
|
|
|
Sciatica caused by lumbar disc herniation (treated with microdiscectomy)
|
|
|
Skin fluorescence in type 1 diabetes
|
|
|
Breast cancer (estrogen-receptor negative)
|
|
|
Serum parathyroid hormone levels
|
|
|
Urinary electrolytes (magnesium/calcium ratio)
|
|
|
Tonsillectomy
|
|
|
Neuroticism
|
disease cluster belonging to disease group psych
|
|
Depressive symptoms measurement (somatic complaints domain)
|
|
|
Excessive daytime sleepiness
|
|
|
Sleep duration
|
duration of sleep, measured either via a self-reporting questionnaire, interview or through obversation in a sleep lab
|
|
Sleep traits (multi-trait analysis)
|
|
|
Insomnia
|
Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition
|
|
Colorectal cancer
|
A large intestine cancer that is located in the colon and/or located in the rectum.
|
|
Hemoglobin concentration
|
|
|
Eosinophil percentage of granulocytes
|
|
|
White blood cell count (basophil)
|
|
|
Midgestational circulating levels of organochlorine pesticides
|
|
|
Midgestational circulating levels of PCBs (fetal genetic effect)
|
|
|
Midgestational circulating levels of PBDEs
|
|
|
Midgestational circulating levels of PBDEs (fetal genetic effect)
|
|
|
Midgestational circulating levels of PCBs
|
|
|
Sum eosinophil basophil counts
|
|
|
Epilepsy and lamotrigine-induced maculopapular eruptions
|
|
|
Multiple myeloma (survival)
|
|
|
Trichloroethylene-induced hypersensitivity syndrome
|
|
|
Hypersomnia during a major depressive episode in bipolar disorder
|
|
|
Post bronchodilator FEV1
|
|
|
Postprandial triglyceride response to high fat diet meal
|
|
|
MGMT methylation in smokers
|
|
|
Parkinson's disease
|
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)|A neurodegenerative disease that results_from degeneration of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions.
|
|
Platelet thrombus formation
|
|
|
Adolescent idiopathic scoliosis
|
|
|
Sight-threatening diabetic retinopathy in type 2 diabetes
|
|
|
Warfarin maintenance dose
|
disease cluster belonging to disease group pharmacogenomic
|
|
Post bronchodilator FEV1/FVC ratio in COPD
|
|
|
Lipoprotein (a) levels
|
|
|
Lung disease severity in cystic fibrosis
|
|
|
White matter lesion progression
|
|
|
White matter lesion progression (adjusted for white matter lesion burden at baseline)
|
|
|
Staphylococcus aureus infection
|
Staphylococcus aureus infection is a bacterial disease caused by infection from the Staphylococcus aureus bacteria.
|
|
Skin and soft tissue Staphylococcus aureus infection
|
|
|
Fibrinogen levels
|
|
|
Late-onset myasthenia gravis
|
|
|
Gastric cancer
|
disease cluster belonging to disease group cancer
|
|
Cardia gastric cancer
|
|
|
Non-cardia gastric cancer
|
|
|
Pelvic organ prolapse (moderate/severe)
|
|
|
Survival in colorectal cancer
|
|
|
Survival in colorectal cancer (non-distant metastatic)
|
|
|
Survival in colorectal cancer (distant metastatic)
|
|
|
Response to lithium treatment in bipolar disorder (continuous phenotype)
|
|
|
Response to lithium treatment in bipolar disorder (dichotomous phenotype)
|
|
|
Frontotemporal dementia
|
A basal ganglia disease characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.
|
|
Hearing loss in noise exposure
|
|
|
Childhood body mass index
|
|
|
Sense of smell
|
|
|
Cannabis use
|
|
|
High fetal hemoglobin in sickle cell disease
|
|
|
Bone mineral density (Ward's triangle area)
|
|
|
Takayasu arteritis
|
|
|
Axial length
|
|
|
Corneal curvature
|
|
|
Change in intraocular pressure in response to steroid treatment (triamcinolone acetonide)
|
|
|
Thrombosis
|
formation within a tissue or the vascular lumen of a thrombus, an aggregation of coagulated blood containing platelets, fibrin, and entrapped cellular elements
|
|
Psoriatic arthritis
|
A syndrome that occurs in humans with psoriasis who also experience symptoms similar to arthritis.
|
|
Squamous cell carcinoma
|
A carcinoma that derives_from squamous epithelial cells.
|
|
Basal metabolic rate
|
|
|
Ulcerative colitis
|
A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.
|
|
Body fat percentage
|
|
|
Alzheimer disease and age of onset
|
|
|
Epstein Barr virus nuclear antigen 1 IgG levels
|
|
|
Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis
|
|
|
Glucocorticoid-induced osteonecrosis (time dependent analysis)
|
|
|
Glucocorticoid-induced osteonecrosis (age 10 years and older)
|
|
|
Glucocorticoid-induced osteonecrosis
|
|
|
Post bronchodilator FEV1/FVC ratio
|
|
|
Longitudinal change in brain amyloid plaque burden
|
|
|
Hepatocellular carcinoma in hepatitis B infection
|
|
|
Classic bladder exstrophy
|
|
|
Sex hormone levels
|
|
|
Cannabis use (initiation)
|
|
|
IgA nephropathy
|
|
|
HIV-1 viral setpoint
|
|
|
Pediatric autoimmune diseases
|
|
|
Pulse pressure
|
disease cluster belonging to disease group cardiovascular
|
|
Mean arterial pressure
|
|
|
Influenza A (H1N1) severity
|
|
|
Mild influenza (H1N1) infection
|
|
|
Influenza A (H1N1) infection
|
|
|
Severe influenza A (H1N1) infection
|
|
|
Ischemic stroke
|
|
|
Cerebrospinal fluid clusterin levels
|
|
|
Plasma clusterin levels
|
|
|
Cerebrospinal fluid clusterin levels in APOEe4- carriers
|
|
|
Response to Pazopanib in cancer (hepatotoxicity)
|
|
|
LDL peak particle diameter (total fat intake interaction)
|
|
|
Triptolide cytotoxicity
|
|
|
Liver fibrosis severity in HIV/hepatitis C co-infection
|
|
|
Thyroid-associated orbitopathy in graves' disease
|
|
|
Celiac disease and Rheumatoid arthritis
|
|
|
Diastolic blood pressure response to hydrochlorothiazide in hypertension
|
|
|
Systolic blood pressure response to hydrochlorothiazide in hypertension
|
|
|
Parkinson's disease (familial, age at onset)
|
|
|
Ideal cardiovascular health (clinical)
|
|
|
Celiac disease
|
A food allergy that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.|A malabsorption syndrome that is precipitated by the ingestion of GLUTEN-containing foods, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.|A food hypersensitivity that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.|A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.
|
|
QRS interval (sulfonylurea treatment interaction)
|
|
|
QT interval (sulfonylurea treatment interaction)
|
|
|
JT interval (sulfonylurea treatment interaction)
|
|
|
Clinical laboratory measurements
|
|
|
Cluster headache
|
A type of headache characterized by repeated attacks of unilateral pain lasting 15 to 180 minutes and associated with local autonomic signs.
|
|
Pneumococcal bacteremia
|
|
|
Bacteremia
|
An infection that has as part bacteria located in the blood.
|
|
Ischemic stroke (cardioembolic)
|
|
|
Verbal-numerical reasoning
|
|
|
Educational attainment
|
|
|
Reaction time
|
|
|
Gastroesophageal reflux disease
|
Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
|
|
Migraine
|
A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing.
|
|
Migraine without aura
|
A migraine that is characterized by migraine headaches that are not accompanied by an aura.
|
|
Pathological gambling
|
An impulse control disorder that involves the uncontrollable impulse to gamble, irrespective of the interference the behaviour has on the individual's life.
|
|
Bone mineral density (hip)
|
disease cluster belonging to disease group metabolic
|
|
Gestational age at birth (maternal effect)
|
|
|
Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time)
|
|
|
Gestational age at birth in premature rupture of membrane-initiated deliveries (maternal effect)
|
|
|
Sjogren's syndrome
|
A hypersensitivity reaction type II disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
|
|
Chronotype
|
|
|
Morning vs. evening chronotype
|
|
|
EGFR mutation-positive lung adenocarcinoma
|
|
|
Sleep duration (oversleepers vs undersleepers)
|
|
|
Small intestine neuroendocrine tumor
|
|
|
Subcutaneous adipose tissue
|
Adipose tissue which is found underneath the skin.
|
|
Pericardial adipose tissue adjusted for height and weight
|
|
|
Visceral adipose tissue adjusted for BMI
|
|
|
Pericardial fat
|
|
|
Visceral adipose tissue/subcutaneous adipose tissue ratio
|
|
|
Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI
|
|
|
Visceral adipose tissue
|
|
|
Alcohol consumption
|
|
|
Alcohol consumption (heavy vs. light/non-drinkers)
|
|
|
Subcutaneous adipose tissue attenuation (Hounsfield unit scale)
|
|
|
Visceral adipose tissue attenuation (Hounslow unit scale)
|
|
|
Schizophrenia
|
A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.|A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
|
|
Extraversion
|
A state in which attention is largely directed outward from the self.
|
|
Subjective well-being
|
|
|
Endometrial endometrioid carcinoma
|
|
|
Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia
|
|
|
Depression
|
A condition characterized by pervasive dysphoric mood, loss of interests, and inability to experience pleasure.
|
|
Primary biliary cholangitis
|
|
|
Hemoglobin levels
|
disease cluster belonging to disease group hematological
|
|
Postoperative atrial fibrillation in coronary artery bypass grafting surgery
|
|
|
Rotator cuff tears
|
|
|
Suicide behavior
|
|
|
Suicide ideation score in major depressive disorder
|
|
|
Suicide
|
|
|
Suicide attempts in major depressive disorder
|
|
|
Response to montelukast in asthma (change in FEV1)
|
|
|
Ear protrusion
|
|
|
Antitragus size
|
|
|
Ear morphology
|
|
|
Lobe size
|
|
|
Lobe attachment
|
|
|
Helix rolling
|
|
|
Folding of antihelix
|
|
|
Mucinous ovarian carcinoma
|
|
|
Metastasis at diagnosis in osteosarcoma
|
|
|
Soluble receptor for advanced glycation end-product levels
|
|
|
Atopic march
|
|
|
Post-traumatic stress disorder
|
A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.|A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event (MeSH).|An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.|An anxiety disease which results from a traumatic experience that results in psychological trauma.
|
|
Setpoint viral load in HIV-1 infection
|
|
|
Dysphagia
|
Difficulty in swallowing.
|
|
Plasma homocysteine levels
|
disease cluster belonging to disease group metabolic
|
|
Cholesterol, total
|
|
|
LDL cholesterol
|
Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.
|
|
HDL cholesterol
|
disease cluster belonging to disease group metabolic
|
|
Triglycerides
|
|
|
Response to interferon beta in multiple sclerosis
|
|
|
Tuberculosis
|
A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.
|
|
Response to fenofibrate (LDL cholesterol levels)
|
|
|
Response to fenofibrate (HDL cholesterol levels)
|
|
|
Response to fenofibrate (total cholesterol levels)
|
|
|
Response to fenofibrate (triglyceride levels)
|
|
|
Parental extreme longevity (95 years and older)
|
|
|
middle facial morphology traits (quantitative measurement)
|
|
|
lower facial morphology traits (quantitative measurement)
|
|
|
facial morphology traits (multivariate analysis)
|
|
|
Hirschsprung disease
|
|
|
Severity of facial solar lentigines
|
|
|
Multiple sclerosis
|
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
|
|
Developmental language disorder
|
|
|
Developmental language disorder (linguistic errors)
|
|
|
Developmental language disorder (syntactic complexity)
|
|
|
Lung cancer
|
A respiratory system cancer that is located_in the lung.
|
|
Smoking status (current vs former)
|
|
|
Smoking behaviour (cigarettes smoked per day)
|
|
|
Lung adenocarcinoma
|
A non-small cell lung carcinoma that derives_from epithelial cells of glandular origin.
|
|
Discordance in emotional problems in monozygotic twins
|
|
|
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder
|
|
|
Cutaneous malignant melanoma
|
disease cluster belonging to disease group cancer
|
|
Fentanyl consumption in laparoscopic-assisted colectomy (first 24 hours)
|
|
|
Left superior temporal gyrus thickness (schizophrenia interaction)
|
|
|
Anthracycline-induced cardiotoxicity in childhood cancer
|
|
|
Staphylococcus aureus nasal carriage (persistent)
|
|
|
Staphylococcus aureus nasal carriage (intermittent)
|
|
|
Diabetic kidney disease
|
|
|
Coronary artery aneurysm in Kawasaki disease
|
|
|
Cannabis dependence symptom count
|
|
|
Membranous nephropathy
|
|
|
Anti-thyroid drug induced agranulocytosis
|
|
|
Non-chemotherapy drug induced agranulocytosis
|
|
|
S-phenylmercapturic acid levels in smokers
|
|
|
Estrogen receptor status in HER2 negative breast cancer
|
|
|
Estrogen receptor status in breast cancer
|
|
|
Attention function in attention deficit hyperactive disorder
|
|
|
Amyotrophic lateral sclerosis
|
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts (MeSH).|An autosomal dominant inherited form of amyloidosis.|A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
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Pre bronchodilator FEV1
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Pre bronchodilator FEV1/FVC ratio
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Urinary metabolites
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Myositis
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An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders.|Inflammation of a muscle or muscle tissue.
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Alcohol dependence
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A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)|Disorders related to or resulting from abuse or mis-use of alcohol.
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Postburn hypertrophic scarring severity
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Bone mineral density (spine) and age at menarche
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Bone mineral density (hip) and age at menarche
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Soluble interleukin-2 receptor subunit alpha
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Mitral valve prolapse
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A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.
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Antipsychotic drug-induced weight gain
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Antipsychotic drug-induced weight gain (time interaction)
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Plasma lactate levels
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Eating disorder in bipolar disorder
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Bipolar disorder and eating disorder
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Nicotine dependence
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Carotid intima media thickness
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Adiponectin levels
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Adiponectin levels (BMI-adjusted)
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Response to serotonin reuptake inhibitors in non-psychotic unipolar depression
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Severe malaria
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disease cluster belonging to disease group infection
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Cingulate cortical amyloid beta load
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Longitudinal alcohol consumption
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Juvenile osteochondritis dissecans
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Corticobasal degeneration
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Acute kidney injury in coronary artery bypass surgery (creatinine rise)
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Joint damage progression in ACPA-negative rheumatoid arthritis
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Cardiovascular disease in hypertension (ACE inhibitor interaction)
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Cardiovascular disease in hypertension (calcium channel blocker interaction)
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Myocardial infarction in hypertension (calcium channel blocker interaction)
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Gastric adenocarcinoma (histologically verified)
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Gait variability
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Gait rhythm
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Tandem gait
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Neuropathic pain in type 2 diabetes
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Rheumatoid factor seropositivity in rheumatoid arthritis
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Major depressive disorder (stressful life events interaction)
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Spherical equivalent (joint analysis main effects and education interaction)
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Aggressiveness in attention deficit hyperactivity disorder
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Myeloid white cell count
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Loneliness
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Loneliness (linear analysis)
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Loneliness (multivariate analysis)
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Optic cup area
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Vertical cup-disc ratio
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Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)
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Basophil percentage of white cells
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Small vessel stroke
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Basophil percentage of granulocytes
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Venous thromboembolism adjusted for sickle cell variant rs77121243-T
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Resting heart rate
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Creatinine levels
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Urea levels
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Waist-to-hip ratio adjusted for body mass index
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Clopidogrel active metabolite levels
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Response to clopidogrel therapy
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Melanoma
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A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)|A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
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Carotid plaque burden
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Gallbladder cancer
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A biliary tract cancer that is located_in the gallbladder.
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Inflammatory bowel disease
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An intestinal disease characterized by inflammation located_in all parts of digestive tract.
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Drug-induced liver injury (terbinafine)
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Drug-induced hepatocellular liver injury
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Drug-induced cholestatic/mixed liver injury
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Drug-induced liver injury
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A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment.
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Optic disc area
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Intraocular pressure
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Presence of antiphospholipid antibodies
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Resistance to antihypertensive treatment in hypertension
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Chronic bronchitis and chronic obstructive pulmonary disease
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Chronic bronchitis in chronic obstructive pulmonary disease
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Manganese levels
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Molybdenum levels
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Cadmium levels
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Copper levels
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Mercury levels
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Lead levels
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Zinc levels
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Psoriasis vulgaris
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disease cluster belonging to disease group immune
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Cutaneous psoriasis
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Vascular endothelial growth factor levels
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White matter hyperintensities in ischemic stroke
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Vitamin D levels
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Calcaneal bone ultrasound measurement (speed of sound)
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Glaucoma (high intraocular pressure)
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Anxiety disorder (factor score)
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Inguinal hernia
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An intestinal disease characterized by a protrusion of abdominal cavity contests through the inguinal canal.
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Rapid functional decline in sporadic amyotrophic lateral sclerosis
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Sex ratio
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Triglyceride levels
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Waist circumference
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The measurement around the body at the level of the ABDOMEN and just above the hip bone. The measurement is usually taken immediately after exhalation.
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Waist circumference adjusted for body mass index
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Chronic lymphocytic leukemia
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A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
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Post bronchodilator FEV1 in COPD
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Manic episodes in bipolar disorder
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Depressive episodes in bipolar disorder
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Depressive and manic episodes in bipolar disorder
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Narcolepsy with cataplexy
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A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
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Yu-Zhi constitution type in type 2 diabetes
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Response to simvastatin treatment (PCSK9 protein level change)
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Response to inhaled glucocorticoid treatment in asthma (change in FEV1)
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Longevity
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The length of time of an organism's life.
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NT-proBNP levels in acute coronary syndrome
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Eyebrow thickness
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Scalp hair shape
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Monobrow thickness
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Hair greying
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Beard thickness
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Hair color
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Color of hair or fur.
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Advanced age-related macular degeneration
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Low high density lipoprotein cholesterol levels
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Balding
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Cerebral amyloid deposition (PET imaging)
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Cognitive decline rate in late mild cognitive impairment
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Periodontal disease-related phenotype (Socransky)
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Periodontal disease related phenotype (PCT3)
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Periodontal disease related phenotype (PCT5)
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Betaine levels in individuals undergoing cardiac evaluation
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Obstructive sleep apnea trait (apnea hypopnea index)
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Obstructive sleep apnea (average oxygen saturation during sleep)
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Obstructive sleep apnea trait (average respiratory event duration)
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Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis
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Congenital left-sided heart lesions
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Incident coronary heart disease
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Incident myocardial infarction
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Survival in endocrine treated breast cancer (estrogen-receptor positive)
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Response to zileuton treatment in asthma (FEV1 change interaction)
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Bone mineral accretion in asthma (oral corticosteroid dose interaction)
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Paclitaxel-induced cytotoxicity
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Pyoderma gangrenosum in inflammatory bowel disease
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Erythema nodosum in inflammatory bowel disease
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Exudative age-related macular degeneration
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Myasthenia gravis
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OMIM mapping confirmed by DO. [SN].
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Subcortical brain region volumes
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Ischemic stroke (large artery atherosclerosis)
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Ischemic stroke (small artery occlusion)
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Ischemic stroke (undetermined subtype)
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White matter hyperintensity burden
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Systolic blood pressure (cigarette smoking interaction)
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Thoracic-to-hip circumference ratio
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Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging)
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Cerebrospinal fluid p-Tau181p:AB1-42 ratio
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Cerebral amyloid deposition positivity (PET imaging)
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Exploratory eye movement dysfunction in schizophrenia (responsive search score)
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Exploratory eye movement dysfunction in schizophrenia (number of eye fixations)
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antipsychotic drug dosage in schizophrenia or schizoaffective disorder
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Glomerular filtration rate in non diabetics (creatinine)
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Glomerular filtration rate in diabetics (creatinine)
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Glomerular filtration rate (cystatin C)
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Chronic kidney disease
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Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)|The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
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Glomerular filtration rate (creatinine)
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Exploratory eye movement dysfunction in schizophrenia (cognitive search score)
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Obsessive-compulsive symptoms
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Serum lycopene concentrations
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Early response to risperidone in schizophrenia
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Perioperative myocardial infarction in coronary artery bypass surgery
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Blond vs non-blond hair color
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Brown vs. non-brown hair color
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Light vs. dark hair color
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Red vs non-red hair color
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disease cluster belonging to disease group developmental
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Black vs. non-black hair color
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Cognitive function
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Motion sickness
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OMIM mapping confirmed by DO. [SN].
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Response to Homoharringtonine (cytotoxicity)
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C-reactive protein levels in ischemic stroke
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Fibrinogen levels in ischemic stroke
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Platinum-induced myelosuppression in non-small cell lung cancer
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Total ventricular volume (Alzheimer's disease interaction)
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Entorhinal cortical thickness
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Entorhinal cortical volume
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Whole-brain volume
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Hippocampal volume
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Measurement of the volume of the hippocampus
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Entorhinal cortical thickness (Alzheimer's disease interaction)
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Total ventricular volume
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Entorhinal cortical volume (Alzheimer's disease interaction)
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Whole-brain volume (Alzheimer's disease interaction)
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Alzheimer's disease or small vessel stroke
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Response to anti-TNF therapy in rheumatoid arthritis
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World class endurance athleticism
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Forced expiratory volume in 1 second (occupational environmental exposures interaction)
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Calcium levels
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Serum alpha1-antitrypsin levels
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Urinary albumin-to-creatinine ratio in diabetes
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Urinary albumin-to-creatinine ratio in non-diabetics
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Urinary albumin-to-creatinine ratio
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Dementia and core Alzheimer's disease neuropathologic changes
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Neurofibrillary tangles
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Pathological protein aggregates formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate in an insoluble form.
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Neuritic plaque
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Kidney stones
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Microalbuminuria
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Lewy body disease
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Vascular brain injury
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Hippocampal sclerosis
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Cerebral amyloid angiopathy
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An amyloidosis where amyloid protein progressively deposits in cerebral blood vessel walls with subsequent degenerative vascular changes that usually result in spontaneous cerebral hemorrhage, ischemic lesions and progressive dementia.
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Proteinuria in chronic kidney disease
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Glomerular filtration rate in chronic kidney disease
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Proteinuria and chronic kidney disease
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Pediatric areal bone mineral density (radius)
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Pediatric bone mineral content (radius)
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Low bone mineral density (spine)
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Low bone mineral density (hip)
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Colorectal or endometrial cancer
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Skin colour saturation
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Perceived skin darkness
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Skin sensitivity to sun
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The response of human skin to sun exposure.
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Obesity in adult survivors of childhood cancer exposed to cranial radiation
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Obesity in adult survivors of childhood cancer not exposed to cranial radiation
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Magnesium levels
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Lachrymal/Salivary gland lesion in type 1 autoimmune pancreatitis
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Cough in response to angiotensin-converting enzyme inhibitor drugs
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Nickel levels
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Chromium levels
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Cobalt levels
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Aluminium levels
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Renal cell carcinoma
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A carcinoma arising from the renal parenchyma. The incidence of renal cell carcinoma has increased by 35% from 1973 to 1991. There is a strong correlation between cigarette smoking and the development of renal cell carcinoma. The clinical presentation includes : hematuria, flank pain and a palpable lumbar mass. A high percentage of renal cell carcinomas are diagnosed when an ultrasound is performed for other purposes. Diagnostic procedures include: ultra sound, intravenous pyelography and computed tomography (CT). Radical nephrectomy is the standard intervention procedure. Renal cell carcinoma is generally considered to be resistant to radiation treatment and chemotherapy.|A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
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IgG1 response to Plasmodium falciparum antigen (GLURP)
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IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7)
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Glioblastoma
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Non-glioblastoma glioma
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Glioma
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Adenocarcinoma
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A type of carcinoma derived from glandular tissue or in which tumor cells form recognizable glandular structures.|A malignant epithelial tumor with a glandular organization.
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Early childhood aggressive behavior
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Middle childhood and early adolescence aggressive behavior
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Childhood and early adolescence aggressive behavior
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Colorectal cancer (oestrogen-progestogen hormone therapy interaction)
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Body mass index (age interaction)
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Airway imaging phenotypes
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Emphysema imaging phenotypes
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Percentage gas trapping
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Progression free survival in metastatic colorectal cancer (CAPOX-B vs CAPOX-B plus cetuximab)
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Asparaginase hypersensitivity in acute lymphoblastic leukemia
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Lapatinib-induced hepatotoxicity
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Multiple myeloma and monoclonal gammopathy
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Sporadic pituitary adenoma
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Peak creatinine levels in vancomycin therapy
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Breast size
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Is a quantification of some aspect of breast size
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Photic sneeze reflex
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Hypothyroidism
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A deficiency of thyroid hormone.
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Chin dimples
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Allergy
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Childhood ear infection
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Depressive symptoms (stressful life events interaction)
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Atrial fibrillation
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A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.
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Palmitoleic acid (16:1n-7) levels
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Vaccenic acid (18:1n-7) levels
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Oleic acid (18:1n-9) levels
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Gondoic acid (20:1n-9) levels
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Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder
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Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease
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Body mass index (change over time) in cancer or chronic obstructive pulmonary disease
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Body mass index (change over time) in lung cancer
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Body mass index (change over time) in gastrointestinal cancer
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Body mass index (change over time) in chronic obstructive pulmonary disease
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Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease
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|
Body mass index (change over time) in cancer
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|
|
Essential tremor
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A movement disorder that causes involuntary tremors, especially in the hands. It occurs alone without other neurological signs and symptoms.
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Night sleep phenotypes
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Hepatocellular carcinoma in post hepatitis C eradication by interferon therapy
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Acute-on-chronic liver failure in hepatitis B
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|
Emotional dysregulation
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|
Thyroid cancer
|
An endocrine gland cancer located_in the thryoid gland located in the neck below the thyroid cartilage.
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|
Carotenoid levels (alpha-carotene)
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|
Circulating chromogranin peptide levels
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CTACK levels
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Growth-regulated protein alpha levels
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Eotaxin levels
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|
Gut microbiota (bacterial taxa)
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|
Menarche (age at onset)
|
disease cluster belonging to disease group reproduction
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Age at voice drop
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|
Prostate-specific antigen levels
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|
Prostate-specific antigen levels (conditioned on lead SNPs)
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|
Monobrow
|
|
|
Myopia
|
A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.
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Nose size
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Joint mobility (Beighton score)
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|
Systolic blood pressure (long-term average)
|
|
|
Diastolic blood pressure (long-term average)
|
|
|
Mean arterial pressure (long-term average)
|
|
|
Paneth cell defects in Crohn's disease
|
|
|
Alzheimer's disease
|
A dementia that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting in late middle age and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability.|A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.|A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)|A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
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Alzheimer's disease (APOE e4 interaction)
|
|
|
Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications
|
|
|
Serum galactose-deficient IgA1 levels
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|
|
Multiple system atrophy (pathologically confirmed)
|
|
|
Multiple system atrophy
|
OMIM mapping confirmed by DO. [LS].
|
|
Post traumatic stress disorder symptom count in trauma-exposed individuals
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|
|
Alcohol misuse (trauma interaction)
|
|
|
Adiponectin levels in pregnancy
|
|
|
Body fat mass
|
|
|
Spine bone mineral density and alcohol drinking
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|
|
Osteoarthritis (with total hip replacement)
|
|
|
Bortezomib-induced peripheral neuropathy in multiple myeloma
|
|
|
Immune response to measles vaccine (measles-specific neutralising antibody titre)
|
|
|
Immune response to measles vaccine (measles-induced IFN gamma)
|
|
|
Urinary 1,3-butadiene metabolite levels in smokers
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|
|
Skin pigmentation
|
Coloration of the skin.
|
|
Systemic sclerosis
|
|
|
Vasculitis associated with antineutrophil cytoplasmic antibody reactive to myeloperoxidase
|
|
|
Antineutrophil cytoplasmic antibody-associated vasculitis
|
|
|
Isovolumetric relaxation time
|
|
|
Peak velocity of the mitral A-wave
|
|
|
Left ventricle diastolic internal dimension
|
|
|
Aortic root size
|
The aortic root size is the size of the part of the ascending aorta beginning at the aortic annulus and extending to the sinotubular junction
|
|
Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.
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|
|
Left ventricular mass
|
disease cluster belonging to disease group cardiovascular
|
|
Left ventricular fractional shortening
|
|
|
Liver injury in anti-retroviral drug treated HIV
|
|
|
Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis
|
|
|
Daytime sleep phenotypes
|
|
|
QRS duration
|
QRS duration is a measurement of the combined duration of the Q, R and S waves of the human heart's electric cycle
|
|
QRS complex (12-leadsum)
|
|
|
QRS complex (Cornell)
|
|
|
QRS complex (Sokolow-Lyon)
|
|
|
Liver injury in anti-tuberculosis drug treatment
|
|
|
Methadone dose in opioid dependence
|
|
|
Basal cell carcinoma
|
A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471).
|
|
Self-reported tiredness
|
|
|
Trans-epidermal water loss
|
|
|
Interleukin-2 receptor antagonist levels
|
|
|
Platelet-derived growth factor BB levels
|
|
|
Macrophage inflammatory protein 1b levels
|
|
|
Immunoglobulin light chain (AL) amyloidosis
|
|
|
Opioid dependence
|
disease cluster belonging to disease group chemdependency
|
|
Gut microbiota (functional units)
|
|
|
QT interval (tricyclic/tetracyclic antidepressant use interaction)
|
|
|
RR interval (tricyclic/tetracyclic antidepressant use interaction)
|
|
|
Incident atrial fibrillation
|
|
|
Prevalent atrial fibrillation
|
|
|
Exhaled nitric oxide output
|
|
|
Exhaled nitric oxide levels
|
disease cluster belonging to disease group other
|
|
Nicotine metabolite ratio
|
|
|
Lung function (FEV1)
|
|
|
Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)
|
|
|
Protein C levels
|
|
|
Gallstone disease
|
|
|
Interleukin-18 levels
|
|
|
Interleukin-17 levels
|
|
|
Interleukin-7 levels
|
|
|
Interleukin-13 levels
|
|
|
Interleukin-10 levels
|
|
|
Stem cell growth factor beta levels
|
|
|
TRAIL levels
|
|
|
Endometriosis
|
The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.
|
|
Ovarian disease with few adhesions
|
|
|
Deep ovarian and/or rectovaginal disease with dense adhesions
|
|
|
Plasma thyroid-stimulating hormone levels
|
|
|
Small cell lung carcinoma
|
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)|A highly aggressive subtype of lung carcinoma characterized by the presence of malignant small cells and necrosis. Metastatic disease is usually present at the time of diagnosis.|A highly aggressive subtype of lung carcinoma characterized by the presence of malignant small cells and necrosis. Metastatic disease is usually present at the time of diagnosis. (NCI05)
|
|
Lung cancer in ever smokers
|
|
|
Lung cancer in never smokers
|
|
|
Nonalcoholic steatohepatitis-derived hepatocellular carcinoma
|
|
|
Heart rate variability traits (RMSSD)
|
|
|
Heart rate variability traits (SDNN)
|
|
|
Heart rate variability traits (pvRSA/HF)
|
|
|
Autism spectrum disorder or schizophrenia
|
|
|
Testicular germ cell tumor
|
|
|
Insomnia complaints
|
|
|
Insomnia complaints (continuous)
|
|
|
Insomnia complaints (dichotomous)
|
|
|
Major depression and alcohol dependence
|
|
|
Extrinsic epigenetic age acceleration
|
|
|
Intrinsic epigenetic age acceleration
|
|
|
Problematic alcohol use in trauma-exposed individuals
|
|
|
Facial emotion recognition
|
|
|
Facial emotion recognition (happy faces)
|
|
|
Facial emotion recognition (sad faces)
|
|
|
Facial emotion recognition (angry faces)
|
|
|
Facial emotion recognition (fearful faces)
|
|
|
Late-onset Alzheimer's disease
|
|
|
Vaso-occlusive pain in sickle-cell anemia
|
|
|
Menopause (age at onset)
|
disease cluster belonging to disease group reproduction
|
|
Heart rate
|
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
|
|
Food allergy
|
A hypersensitivity reaction type I disease that is an abnormal response to a food, triggered by the body's immune system.
|
|
Peanut allergy
|
|
|
Hen's egg allergy
|
|
|
Allergic disease (asthma, hay fever or eczema)
|
|
|
Paclitaxel disposition in epithelial ovarian cancer
|
|
|
Carboplatin disposition in epthelial ovarian cancer
|
|
|
Alcohol consumption over the past year
|
|
|
Colorectal adenoma (advanced)
|
|
|
Diastolic blood pressure x sodium interaction (1df test)
|
|
|
Systolic blood pressure x sodium interaction (2df test)
|
|
|
Diastolic blood pressure x sodium interaction (2df test)
|
|
|
Mean arterial pressure x sodium interaction (2df test)
|
|
|
Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)
|
|
|
Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms
|
|
|
Cerebrospinal fluid t-tau levels
|
|
|
Age-related macular degeneration (SNP x mitochondrial G12771A interaction)
|
|
|
Verbal memory performance (immediate recall change)
|
|
|
Verbal memory performance (residualized delayed recall level)
|
|
|
Pediatric non-alcoholic fatty liver disease activity score
|
|
|
Liver fibrosis in pediatric non-alcoholic fatty acid liver disease
|
|
|
Pediatric nonalcoholic steatohepatitis
|
|
|
Fear of pain
|
|
|
Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia
|
|
|
Fear of minor pain
|
|
|
Hepatocellular carcinoma in hepatitis C infection
|
|
|
Atopy
|
|
|
Primary biliary cirrhosis
|
A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.
|
|
Alcohol consumption in current drinkers
|
|
|
Amyotrophic lateral sclerosis (sporadic)
|
|
|
Graves' disease
|
An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.
|
|
Hashimoto thyroiditis
|
|
|
Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis)
|
|
|
IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis)
|
|
|
IgG sialylation phenotypes (multivariate analysis)
|
|
|
IgG galactosylation phenotypes (multivariate analysis)
|
|
|
IgG disialylation phenotypes (multivariate analysis)
|
|
|
IgG monogalactosylation phenotypes (multivariate analysis)
|
|
|
IgG monosialylation phenotypes (multivariate analysis)
|
|
|
IgG digalactosylation phenotypes (multivariate analysis)
|
|
|
IgG fucosylation phenotypes (multivariate analysis)
|
|
|
Neuroblastoma (11q deletion)
|
|
|
Neuroblastoma (MYCN amplification)
|
|
|
Shingles
|
|
|
Chickenpox
|
A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human herpesvirus 3, which is transmitted_by direct contact with secretions from the rash, or transmitted_by droplet spread of respiratory secretions. The infection has_symptom anorexia, has_symptom myalgia, has_symptom nausea, has_symptom fever, has_symptom headache, has_symptom sore throat, and has_symptom blisters.
|
|
Cold sores
|
|
|
Mumps
|
A viral infectious disease that results_in inflammation located_in salivary gland, has_material_basis_in Mumps virus, which is transmitted_by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted_by contaminated fomites. The infection has_symptom fever, has_symptom headache, has_symptom muscle aches, has_symptom tiredness, has_symptom loss of appetite, has_symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face.
|
|
Plantar warts
|
|
|
Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction)
|
|
|
Spontaneous preterm birth (maternal effect)
|
|
|
Knee osteoarthritis
|
|
|
Yeast infection
|
|
|
Myringotomy
|
|
|
Bacterial meningitis
|
|
|
Urinary tract infection frequency
|
|
|
Hepatitis A
|
A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus, which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.
|
|
Strep throat
|
|
|
Mononucleosis
|
|
|
Hepatitis B
|
A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus, which is transmitted_by sexual contact, transmitted_by blood transfusions, and transmitted_by fomites like needles or syringes. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.
|
|
Scarlet fever
|
An upper respiratory tract disease described as an acute contagious disease caused by Group A bacteria of the genus Streptococcus (especially various strains of S. pyogenes) and characterized by inflammation of the nose, throat, and mouth, generalized toxemia, and a red rash.
|
|
Pneumonia
|
A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.
|
|
1,5-anhydroglucitol levels
|
|
|
Squamous cell lung carcinoma
|
|
|
Cerebral blood flow
|
|
|
Gut microbiota (beta diversity)
|
|
|
Attention deficit hyperactivity disorder symptom score
|
|
|
Diabetes in response to antihypertensive drug treatment (treatment strategy interaction)
|
|
|
Resistin levels
|
|
|
Hepcidin/transferrin saturation ratio
|
|
|
Hepcidin/ferritin ratio
|
|
|
Hepcidin levels
|
|
|
Otitis media
|
A otitis which involves inflammation of the middle ear.
|
|
Otitis media (chronic)
|
|
|
Otitis media (recurrent)
|
|
|
Emphysema distribution in smoking
|
|
|
Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes
|
|
|
Kidney disease (end stage renal disease vs normoalbuminuria) in type 1 diabetes
|
|
|
Chronic kidney disease (severe chronic kidney disease vs normal kidney function) in type 1 diabetes
|
|
|
Kidney disease (early and late stages) in type 1 diabetes
|
|
|
HIV progression (CD4 and viral load)
|
|
|
Response to platinum-based neoadjuvant chemotherapy in cervical cancer
|
|
|
L-arginine levels
|
|
|
B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy)
|
|
|
Nonsyndromic cleft lip with or without cleft palate
|
disease cluster belonging to disease group developmental
|
|
Plasma t-tau levels
|
|
|
Primary sclerosing cholangitis
|
|
|
Pediatric bone mineral content (femoral neck)
|
|
|
Pediatric bone mineral density (femoral neck)
|
|
|
Pediatric bone mineral density (spine)
|
|
|
Pediatric bone mineral content (spine)
|
|
|
Pediatric bone mineral density (hip)
|
|
|
Interferon gamma-induced protein 10 levels
|
|
|
Macrophage Migration Inhibitory Factor levels
|
|
|
Monocyte chemoattractant protein-1 levels
|
|
|
Interleukin-12p70 levels
|
|
|
Interleukin-16 levels
|
|
|
Systolic blood pressure change trajectory
|
|
|
Idiopathic osteonecrosis of the femoral head
|
|
|
Early-onset Parkinson's disease
|
|
|
Vitamin B12 levels
|
|
|
Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)
|
|
|
Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test)
|
|
|
Systolic blood pressure x smoking status (ever vs never) interaction (2df test)
|
|
|
Diastolic blood pressure x smoking status (ever vs never) interaction (1df test)
|
|
|
Obstructive sleep apnea during REM sleep (apnea hypopnea index)
|
|
|
Severe malaria (adjusted for sickle cell variant rs334)
|
|
|
Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel
|
|
|
Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin
|
|
|
Tooth agenesis
|
A tooth disease characterized by failure to develop on or more missing teeth.
|
|
Tooth agenesis (mandibular second premolars)
|
|
|
Tooth agenesis (maxillary lateral incisors)
|
|
|
Tooth agenesis (maxillary second premolars)
|
|
|
Systolic blood pressure (dietary potassium intake interaction)
|
|
|
Nasopharyngeal carcinoma
|
|
|
Nodular sclerosis Hodgkin lymphoma
|
|
|
Mixed cellularity Hodgkin lymphoma
|
|
|
Hodgkin's lymphoma
|
A lymphoma that is marked by the presence of a type of cell called the Reed-Sternberg cell.
|
|
Colonoscopy-negative controls vs population controls
|
|
|
Smoking status (heavy vs light)
|
|
|
Caudate activity during reward
|
|
|
White matter microstructure in first episode schizophrenia (right posterior cingulate cortex)
|
|
|
Total mean fractional anisotropy measurement in first episode schizophrenia
|
|
|
White matter microstructure in first episode schizophrenia (left posterior cingulate cortex)
|
|
|
White matter microstructure in first episode schizophrenia (left inferior parietal cortex)
|
|
|
Abnormal white matter microstructure in first episode schizophrenia (multivariate analysis)
|
|
|
White matter microstructure in first episode schizophrenia (left anterior cingulate cortex)
|
|
|
White matter microstructure in first episode schizophrenia (right anterior cingulate cortex)
|
|
|
Craniofacial microsomia
|
|
|
Estrone conjugates/estrone ratio in resected early stage estrogen-receptor positive breast cancer
|
|
|
Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer
|
|
|
Plasma estrone levels in resected estrogen-receptor positive breast cancer
|
|
|
Plasma androstenedione levels in resected early stage-receptor positive breast cancer
|
|
|
Plasma estrone conjugates levels in resected early stage estrogen-receptor positive breast cancer
|
|
|
Facial morphology (factor 3, length of philtrum)
|
|
|
Motor development (prenatal lead exposure interaction)
|
|
|
Mental development (prenatal lead exposure interaction)
|
|
|
Borderline personality disorder
|
A personality disorder that involves a prolonged disturbance of personality function characterized by depth and variability of moods.
|
|
Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous)
|
|
|
Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (dichotomous)
|
|
|
Rate of cognitive decline in mild cognitive impairment (time interaction)
|
|
|
Anorexia nervosa (excluding migration to or from binge-eating disorder or bulimia nervosa)
|
|
|
Facial morphology (factor 17, height of vermillion upper lip)
|
|
|
Neurocognitive impairment in HIV-1 infection (continuous)
|
|
|
HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment)
|
|
|
HIV-associated neurocognitive disorder (mild neurocognitive disorder)
|
|
|
HIV-associated neurocognitive disorder
|
|
|
Neurocognitive impairment in HIV-1 infection (dichotomous)
|
|
|
HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment)
|
|
|
Facial morphology (factor 9, facial height related to vertical position of nasion)
|
|
|
Peripheral arterial disease (traffic-related air pollution interaction)
|
|
|
Facial morphology (factor 22)
|
|
|
Aggressive periodontitis
|
A periodontitis that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as dental plaque and dental calculus resulting in inflammation and a loss of periodontium.
|
|
Weight
|
|
|
Lean body mass
|
|
|
Waist-hip ratio
|
The waist circumference measurement divided by the hip circumference measurement. For both men and women, a waist-to-hip ratio (WHR) of 1.0 or higher is considered at risk for undesirable health consequences, such as heart disease and ailments associated with OVERWEIGHT. A healthy WHR is 0.90 or less for men, and 0.80 or less for women. (National Center for Chronic Disease Prevention and Health Promotion, 2004)
|
|
Trunk fat mass
|
|
|
Telomere length
|
A measurement of telomere length measures the number of TTAGGG repeats at the end of the chromosome. As cell division proceeds telomeres shorten, telomere length is measure of cellular aging.
|
|
Hip circumference adjusted for BMI
|
|
|
Red blood cell density in sickle cell anemia
|
|
|
Obstetric antiphospholipid syndrome
|
|
|
Cocaine use disorder
|
|
|
Cocaine use disorder x non-traditional parental care interaction
|
|
|
Cocaine use disorder x change in residence interaction
|
|
|
Cocaine use disorder x household tobacco use interaction
|
|
|
Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension
|
|
|
Systolic blood pressure response to thiazide and thiazide-like diuretics in hypertension
|
|
|
Apolipoprotein A1 levels
|
|
|
Urinary metabolite levels in chronic kidney disease
|
|
|
Graft survival time in renal transplantation (donor effect)
|
|
|
Graft survival time in renal transplantation (donor effect) x APOL1 genotype interaction
|
|
|
Salivary metabolite levels
|
|
|
Cardioembolic stroke (CCSp classification)
|
|
|
Cardioembolic stroke (TOAST classification)
|
|
|
Cardioembolic stroke (CCS and TOAST classification)
|
|
|
Cardioembolic stroke (CCS or TOAST classification)
|
|
|
Large artery stroke (CCSp classification)j
|
|
|
Large artery stroke (TOAST classification)
|
|
|
Large artery stroke (CCS and TOAST classification)
|
|
|
Large artery stroke (CCS or TOAST classification)
|
|
|
Small vessel stroke (CCSp classification)
|
|
|
Small vessel stroke (CCS and TOAST classification)
|
|
|
Small vessel stroke (CCS or TOAST classification)
|
|
|
Cardioembolic stroke (CCSc classification)
|
|
|
Gout (combined type)
|
|
|
Gout (normal type)
|
|
|
Femoral neck bone mineral density
|
|
|
Trunk fat mass adjusted for trunk lean mass
|
|
|
Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass
|
|
|
Idiopathic downbeat nystagmus
|
|
|
Eosinophilic granulomatosis with polyangiitis (ANCA negative)
|
|
|
Eosinophilic granulomatosis with polyangiitis
|
|
|
Bilirubin levels
|
|
|
Relative fat intake
|
|
|
Relative protein intake
|
|
|
Relative carbohydrate intake
|
|
|
Relative sugar intake
|
|
|
Carotid intima media thickness (mean)
|
|
|
Carotid intima media thickness (maximum)
|
|
|
Aortic valve area
|
|
|
Hematological and biochemical traits
|
|
|
Physiological traits
|
|
|
Cholesterol
|
|
|
Lung function
|
disease cluster belonging to disease group other
|
|
Machado-Joseph disease (age at onset)
|
|
|
TPE interval (resting)
|
|
|
TPE interval (response to exercise)
|
|
|
TPE interval (recovery after exercise)
|
|
|
Serum immune biomarker levels
|
|
|
Cerebrospinal fluid immune biomarker levels
|
|
|
Obsessive compulsive disorder severity
|
|
|
Compulsion score in obsessive compulsive disorder
|
|
|
Obsession score in obsessive compulsive disorder
|
|
|
Brain imaging measurements (variance)
|
|
|
Meat-related diet
|
|
|
Pork consumption
|
|
|
Poultry consumption
|
|
|
Raw vegetable consumption
|
|
|
Serum alkaline phosphatase levels
|
|
|
Gamma glutamyl transferase levels
|
|
|
Childhood maltreatment
|
|
|
Diastolic blood pressure x quantitative lifestyle risk score interaction (1df test)
|
|
|
Diastolic blood pressure x quantitative lifestyle risk score interaction (2df test)
|
|
|
Diastolic blood pressure x dichotomous lifestyle risk score interaction (1df test)
|
|
|
Diastolic blood pressure x dichotomous lifestyle risk score interaction (2df test)
|
|
|
Systolic blood pressure x quantitative lifestyle risk score interaction (1df test)
|
|
|
Systolic blood pressure x quantitative lifestyle risk score interaction (2df test)
|
|
|
Systolic blood pressure x dichotomous lifestyle risk score interaction (1df test)
|
|
|
Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test)
|
|
|
Adult onset Still's disease
|
|
|
Heel bone mineral density
|
|
|
Fractures
|
|
|
Vertical cup-disc ratio (adjusted for vertical disc diameter)
|
|
|
Vertical cup-disc ratio (multi-trait analysis)
|
|
|
Apolipoprotein B levels
|
|
|
BMI at adiposity peak
|
|
|
Age at adiposity rebound
|
|
|
BMI at adiposity rebound
|
|
|
Fish- and plant-related diet
|
|
|
Beef consumption
|
|
|
Bipolar disorder or body mass index
|
|
|
Bipolar disorder or type 2 diabetes
|
|
|
Coronary artery disease in type 1 diabetes
|
|
|
Processed meat consumption
|
|
|
Oily fish consumption
|
|
|
Non-oily fish consumption
|
|
|
Lamb consumption
|
|
|
Fruit consumption
|
|
|
Cooked vegetable consumption
|
|
|
Mosaic loss of chromosome Y (Y chromosome dosage)
|
|
|
Voxel-wise structural brain imaging measurements in Alzheimer’s disease
|
|
|
Metopic nonsyndromic craniosynostosis
|
|
|
Cerebral cortex AV-45 amyloid PET measurement
|
|
|
Smoking initiation (ever regular vs never regular)
|
|
|
Urinary metabolite modules (eigenmetabolites) in chronic kidney disease
|
|
|
Hallux valgus
|
Lateral deviation of the great toe (i.e., in the direction of the little toe).
|
|
Lipoprotein (a) levels in response to niacin in statin-treated individuals
|
|
|
HDL cholesterol change in response to niacin in statin-treated individuals
|
|
|
Rapid automised naming and rapid alternating stimulus test performance
|
|
|
Latent naming speed
|
|
|
Rapid automised naming of letters
|
|
|
Rapid alternating stimulus test for letters/numbers
|
|
|
Thoracic aortic calcification levels
|
|
|
Abdominal aortic calcification levels
|
|
|
Knee pain
|
|
|
Age-related hearing impairment (low/mid frequency)
|
|
|
Age-related hearing impairment (high frequency)
|
|
|
Hypotension and cognitive impairment
|
|
|
Proliferative diabetic retinopathy
|
|
|
Chronic postoperative pain
|
|
|
Type 2 diabetes (adjusted for BMI)
|
|
|
Anxiety
|
Apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus.
|
|
Anxiety disorders
|
|
|
Low density lipoprotein cholesterol levels
|
|
|
Parkinson's disease or first degree relation to individual with Parkinson's disease
|
|
|
LDL cholesterol levels x short total sleep time interaction (2df test)
|
|
|
LDL cholesterol levels x long total sleep time interaction (2df test)
|
|
|
Triglyceride levels x long total sleep time interaction (2df test)
|
|
|
HDL cholesterol levels x short total sleep time interaction (2df test)
|
|
|
Disability (impaired activities of daily living)
|
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|
Cutaneous melanoma or hair colour
|
|
|
Nevus count or cutaneous melanoma
|
|
|
Eosinophilic esophagitis
|
An esophagitis characterized by inflammation involving eosinophils located_in esophagus.
|
|
Glaucoma
|
An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)|Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
|
|
Glaucoma (multi-trait analysis)
|
|
|
Heart failure
|
|
|
Intracerebral hemorrhage
|
bleeding within the cerebrum
|
|
Hypertriglyceridemia
|
A condition of elevated levels of TRIGLYCERIDES in the blood.
|
|
High fasting blood glucose
|
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|
Low HDL-cholesterol levels
|
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|
Metabolic syndrome
|
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|
Refractive error
|
|
|
Serum metabolite levels (CMS)
|
|
|
Facial morphology
|
Any measurable or observable characteristic related to the shape, structure, color or pattern of the region of the body that includes the front part of the head from the chin to the top of the forehead, where the mouth, eyes, nose, and other features are located.
|
|
Serum sclerostin levels
|
|
|
Protein level change in low calorie diet obesity intervention
|
|
|
Retinal detachment
|
OMIM mapping confirmed by DO. [SN].
|
|
Retinal detachment or retinal break
|
|
|
Retinal detachment with retinal break
|
|
|
Protein levels in obesity
|
|
|
Cataracts (operation)
|
|
|
Cortical thickness
|
Is a quantification of the thickness of brain cortex, e.g. measured by MRI, used in the diagnosis of Alzheimer's disease.
|
|
Youthful appearance (self-reported)
|
|
|
Smoking initiation
|
initation of the habit of smoking, the inhaling and exhaling of tobacco smoke.
|
|
Smoking cessation
|
Discontinuation of the habit of smoking, the inhaling and exhaling of tobacco smoke.
|
|
Smoking status (current vs never)
|
|
|
Smoking status (current vs mixed)
|
|
|
Plasma free amino acid levels (adjusted for one other PFAA)
|
|
|
Body fat distribution (trunk fat ratio)
|
|
|
Non-del(5q) myelodysplastic syndromes
|
|
|
NASH resolution in nonalcoholic steatohepatitis
|
|
|
Pruritus in nonalcoholic steatohepatitis
|
|
|
Skin pigmentation (conditioned on rs1426654 and rs35397)
|
|
|
Occipital lobe volume
|
|
|
Parietal lobe volume
|
|
|
Temporal lobe volume
|
|
|
Stress urinary incontinence
|
|
|
Triglyceride levels x short total sleep time interaction (2df test)
|
|
|
HDL cholesterol levels x long total sleep time interaction (1df test)
|
|
|
Triglyceride levels x short total sleep time interaction (1df test)
|
|
|
HDL cholesterol levels x short total sleep time interaction (1df test)
|
|
|
LDL cholesterol levels x long total sleep time interaction (1df test)
|
|
|
LDL cholesterol levels x short total sleep time interaction (1df test)
|
|
|
Idiopathic pulmonary fibrosis
|
Chronic and progressive fibrosis of the lung parenchyma of unknown cause.
|
|
QT interval
|
The QT interval is a measure of the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle
|
|
Proportion of activated microglia (inferior temporal cortex)
|
|
|
Proportion of activated microglia (midfrontal cortex)
|
|
|
JT interval
|
|
|
Activity variability during wake
|
|
|
Sleep duration (> 10 hours)
|
|
|
Sleep (1/2-day periodicity)
|
|
|
Sleep start time
|
|
|
Sleep (1/3-day periodicity)
|
|
|
Sleep end time
|
|
|
Sleep (1-day periodicity)
|
|
|
Sleep activity levels
|
|
|
Plasma free amino acid levels (adjusted for twenty other PFAAs)
|
|
|
Corneal astigmatism
|
|
|
Refractive astigmatism
|
|
|
Lifetime anxiety disorder
|
|
|
Cerebrospinal fluid sTREM-2 levels
|
|
|
Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis
|
|
|
Two-hour glucose
|
|
|
Impaired insulin sensitivity in response to n-3 PUFA supplementation
|
|
|
LDL cholesterol levels x loop diuretics use interaction
|
|
|
Triglyceride levels x loop diuretics use interaction
|
|
|
Cortical surface area (visual PC2)
|
|
|
HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction
|
|
|
LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction
|
|
|
Triglyceride levels x thiazide or thiazide-like diuretics use interaction
|
|
|
HDL cholesterol levels x loop diuretics use interaction
|
|
|
Interleukin-6 receptor subunit alpha levels
|
|
|
C-X-C motif chemokine 10 levels
|
|
|
CCL24 levels
|
|
|
MHC class I polypeptide-related sequence A levels
|
|
|
CD40 ligand levels
|
|
|
CXCL5 levels
|
|
|
kallikrein-11 levels
|
|
|
epithelial cell adhesion molecule levels
|
|
|
interleukin 17 receptor B levels
|
|
|
interleukin 12 receptor subunit beta-1 levels
|
|
|
vascular endothelial growth factor D levels
|
|
|
E-selectin levels
|
|
|
melanoma-derived growth regulatory protein levels
|
|
|
CCL19 levels
|
|
|
Cortical surface area (global PC1)
|
|
|
Post-bronchodilator lung function in asthma (FVC)
|
|
|
Lung function (FVC) in asthma
|
|
|
Post-bronchodilator lung function in asthma (FEV1/FVC)
|
|
|
LDL cholesterol x physical activity interaction (1df test)
|
|
|
HDL cholesterol x physical activity interaction (1df test)
|
|
|
Response to (pegylated) interferon in HBeAg-negative hepatitis B
|
|
|
Response to (pegylated) interferon in HBeAG-positive hepatitis B
|
|
|
Response to (pegylated) interferon in chronic hepatitis B
|
|
|
HDL cholesterol levels x long total sleep time interaction (2df test)
|
|
|
Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide)
|
|
|
COVID-19 (critical illness vs population)
|
|
|
Mastocytosis (KIT D816V positive)
|
|
|
Testosterone levels x fluid intelligence interaction
|
|
|
Body fat distribution (leg fat ratio)
|
|
|
Body fat distribution (arm fat ratio)
|
|
|
Plasma free amino acid levels
|
|
|
Plasma free proline levels
|
|
|
Plasma free asparagine levels
|
|
|
High density lipoprotein cholesterol levels
|
|
|
Physiological dysregulation (Mahalanobis distance)
|
|
|
Hand grip strength (Mahalanobis distance)
|
|
|
Smoking status (heavy vs never)
|
|
|
Lung function in heavy smokers (low FEV1 vs high FEV1)
|
|
|
Lung function in never smokers (high FEV1 vs average FEV1)
|
|
|
Lung function in heavy smokers (high FEV1 vs average FEV1)
|
|
|
Lung function (low FEV1 vs high FEV1)
|
|
|
Lung function in never smokers (low FEV1 vs average FEV1)
|
|
|
Lung function in never smokers (low FEV1 vs high FEV1)
|
|
|
B-cell acute lymphoblastic leukaemia
|
|
|
B-cell acute lymphoblastic leukaemia (high-hyperdiploidy)
|
|
|
Circulating leptin levels in high cardiovascular risk
|
|
|
Circulating leptin levels x sex interaction in high cardiovascular risk
|
|
|
Hippocampal atrophy rate
|
|
|
Circulating leptin levels or fasting insulin levels
|
|
|
Circulating leptin levels or HOMA-B
|
|
|
Circulating leptin levels or HOMA-IR
|
|
|
Circulating leptin levels or type 2 diabetes
|
|
|
Complement factor H binding to malondialdehyde
|
|
|
Response to antiepileptic drugs in genetic generalized epilepsy
|
|
|
Response to valproic acid in genetic generalized epilepsy
|
|
|
Response to lamotrigine in genetic generalized epilepsy
|
|
|
Response to levetiracetam in genetic generalized epilepsy
|
|
|
Response to lamotrigine and valproic acid in genetic generalized epilepsy
|
|
|
White matter hyperintensities
|
|
|
White matter integrity (fractional anisotropy)
|
|
|
White matter integrity (mean diffusivity)
|
|
|
Eye color
|
Color of the iris.
|
|
Eye color (brightness)
|
|
|
Eye color (saturation)
|
|
|
Eye color (hue)
|
|
|
Skin, hair and eye pigmentation (multivariate analysis)
|
|
|
Thyroid autoantibody positivity (anti-thyroglobulin (TgAb) and/or anti-thyroid peroxidase (TPOAb) levels)
|
|
|
Anti-chlamydia trachomatis IgG seropositivity
|
|
|
Dietary macronutrient intake
|
|
|
Coronary artery disease in diabetes
|
|
|
General cognitive ability
|
|
|
Dysmenorrheic pain severity
|
|
|
Menstruation quality of life impact (dysmenorrhea)
|
|
|
Pain medicine use during menstruation
|
|
|
Menstruation quality of life impact (fever)
|
|
|
Response to long-chain n-3 polyunsaturated fatty acid supplementation (change in triglyceride levels)
|
|
|
Café-au-lait macule number in neurofibromatosis type1
|
|
|
Mucinous adenocarcinoma in colorectal cancer
|
|
|
End-stage renal disease
|
|
|
End stage renal disease x APOL1 genotype interaction
|
|
|
End stage renal disease in APOL1 risk genotype-negative individuals
|
|
|
Delta-5 desaturase activity response to n3-polyunsaturated fat supplement
|
|
|
Delta-6 desaturase activity response to n3-polyunsaturated fat supplement
|
|
|
Hepatitis B surface antigen seroclearance in chronic hepatitis B infection
|
|
|
Penicillin allergy
|
|
|
Systolic blood pressure night-to-day ratio in hypertension
|
|
|
Diastolic blood pressure night-to-day ratio in hypertension
|
|
|
Elevated fasting plasma glucose
|
|
|
Parkinson's disease (age of onset)
|
disease cluster belonging to disease group neurological
|
|
Panic disorder
|
An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress.
|
|
Change in serum metabolite levels
|
|
|
Change in serum metabolite levels (CMS)
|
|
|
Decreased low contrast letter acuity in multiple sclerosis
|
|
|
Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes)
|
|
|
HDL cholesterol x physical activity interaction (2df test)
|
|
|
LDL cholesterol x physical activity interaction (2df test)
|
|
|
Nonunion in individuals with fractures
|
|
|
Opioid use cessation
|
|
|
Acute respiratory distress syndrome in sepsis
|
|
|
Estimated glomerular filtration rate
|
|
|
Serum creatinine levels
|
|
|
Allergic rhinitis
|
A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.
|
|
Allergic sensitization
|
|
|
Type 1 diabetes in high risk HLA genotype individuals (time to event)
|
|
|
Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event)
|
|
|
Freckles
|
Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.
|
|
Double-edged eyelids
|
|
|
Thick vs thin eyebrows
|
|
|
Straight vs curly hair
|
|
|
Excessive hairiness
|
|
|
Excessive sweating
|
|
|
Age spots
|
|
|
Household income (MTAG)
|
|
|
Cerebrospinal fluid α-synuclein levels
|
|
|
Self-reported risk-taking behaviour
|
|
|
Alzheimer's disease (onset between ages 58 and 79)
|
|
|
Alzheimer's disease (onset at age over 80)
|
|
|
Low tan response
|
|
|
Rosacea symptom severity
|
|
|
Neuromyelitis optica
|
A central nervous system disease characterized by acute neuritis located_in eye and demyelination located_in optic nerve and located_in spinal cord.
|
|
Neuromyelitis optica (AQP4-IgG-positive)
|
|
|
Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease
|
|
|
Spherical equivalent or myopia (age of diagnosis)
|
|
|
Aseptic loosening in total joint arthroplasty
|
|
|
Optic disc size
|
|
|
Lactose tolerance test
|
|
|
Uric acid levels
|
|
|
Blood glucose levels
|
|
|
Severe aplastic anemia
|
|
|
Cryptosporidiosis
|
A coccidiosis that involves a parasitic protozoan infection of the intestine of humans and a wide range of animals caused by Cryptosporidium species, through contaminated water and food, The symptoms include watery diarrhea, dehydration, weight loss, abdominal pain, fever, nausea and vomiting. Cryptosporidium infections have also been found in other digestive tract organs, the lungs, and conjunctiva. Immunocompromised persons are at greater risk of developing the infection.
|
|
Gynecologic disease
|
|
|
Gynecologic disease (multivariate analysis)
|
|
|
Cervical cancer
|
A female reproductive organ cancer that is located_in the cervix.
|
|
Cervical cancer (MTAG)
|
|
|
Ovarian cancer (MTAG)
|
|
|
Prostate cancer (early onset)
|
|
|
Prostate cancer (advanced)
|
|
|
Cerebrospinal fluid beta-site APP cleaving enzyme levels
|
|
|
Current cigarettes per day in chronic obstructive pulmonary disease
|
|
|
Plasma neurofilament light levels
|
|
|
Non-melanoma skin cancer
|
|
|
Circulating odd-numbered chain saturated fatty acid levels (C17:0)
|
|
|
Disease free survival in colon cancer
|
|
|
Survival in colon cancer
|
|
|
Meningioma
|
A central nervous system cancer that are manifested in the central nervous system and arise from the arachnoid cap cells of the arachnoid villi in the meninges.
|
|
Optic nerve head parameters (multi-trait analysis)
|
|
|
Intraocular pressure and central corneal thickness (multi-trait analysis)
|
|
|
Frontotemporal dementia with GRN mutation (age at onset)
|
|
|
Behavioural changes in frontotemporal lobe dementia
|
|
|
Memory dysfunction in frontotemporal lobe dementia
|
|
|
Frontotemporal dementia (age at onset)
|
|
|
Language impairment in frontotemporal lobe dementia
|
|
|
Parkinsonism in frontotemporal lobe dementia
|
|
|
Frontotemporal dementia with GRN mutation
|
|
|
Parkinson's disease in GBA mutation carriers
|
|
|
Uric acid elevation in response to thiazide-like diuretic in hypertension
|
|
|
Hallucinations in long-term cannabis use
|
|
|
Bone mineral content
|
|
|
Bone mineral density
|
|
|
Central retinal vein equivalent
|
|
|
Central retinal arteriolar equivalent
|
|
|
Cerebrospinal fluid neurofilament light levels
|
|
|
Diabetic macular edema in type 2 diabetes
|
|
|
Proliferative diabetic retinopathy in type 2 diabetes
|
|
|
Uterine fibroids
|
disease cluster belonging to disease group unknown
|
|
Uterine fibroids (MTAG)
|
|
|
Ovarian cancer
|
A female reproductive organ cancer that is located_in the ovary.
|
|
Opioid use disorder
|
|
|
Airflow obstruction in ever smokers
|
|
|
Blood protein levels in cardiovascular risk
|
|
|
Cirrhosis
|
|
|
Cutaneous squamous cell carcinoma
|
disease cluster belonging to disease group cancer
|
|
Complete remission in asthma
|
|
|
Short-term memory (visuospatial task)
|
|
|
Long-term memory (delayed word recall task)
|
|
|
Dermatomyositis or juvenile dermatomyositis
|
|
|
Polymyositis
|
|
|
Idiopathic inflammatory myopathy
|
|
|
Serum total polyunsaturated fatty acid concentration in metabolic syndrome
|
|
|
Serum linoleic acid concentration in metabolic syndrome
|
|
|
Serum omega-3 polyunsaturated fatty acid concentration in metabolic syndrome
|
|
|
Serum omega-6 to omega-3 polyunsaturated fatty acid ratio in metabolic syndrome
|
|
|
Serum omega-6 polyunsaturated fatty acid concentration in metabolic syndrome
|
|
|
Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome
|
|
|
Serum docosahexaenoic fatty acid concentration in metabolic syndrome
|
|
|
Serum polyunsaturated fatty acid concentration x Mediterranean diet adherence interaction in metabolic syndrome
|
|
|
Urate levels
|
|
|
Memory decline
|
disease cluster belonging to disease group aging
|
|
Alcohol consumption (drinks per week)
|
|
|
Coffee consumption
|
Behaviors associated with the ingesting of coffee
|
|
Green tea consumption
|
|
|
Milk consumption
|
|
|
Yoghurt consumption
|
|
|
Natto consumption
|
|
|
Tofu consumption
|
|
|
Midgestational total 25-hydroxyvitamin D levels (maternal genetic effect)
|
|
|
Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect)
|
|
|
Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect)
|
|
|
Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect)
|
|
|
Fish intake frequency
|
|
|
Alcohol consumption (drinkers vs non-drinkers)
|
|
|
Response to ketogenic dietary therapies in epilepsy
|
|
|
Drug-induced liver injury in interferon-beta-treated multiple sclerosis
|
|
|
Basal ganglia growth
|
|
|
White matter growth
|
|
|
Cerebellum growth
|
|
|
Cerebral cortical growth
|
|
|
Right lateral prefrontal cortical growth
|
|
|
Huntington's disease (age at onset)
|
|
|
Coronary heart disease
|
|
|
Diabetes mellitus
|
A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.|A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
|
|
Type 1 diabetes
|
disease cluster belonging to disease group immune
|
|
Urinary calcium excretion
|
|
|
Urinary magnesium excretion
|
|
|
Urinary uric acid excretion
|
|
|
Reading disability
|
|
|
Serum cancer antigen 19.9 levels
|
|
|
Serum cancer antigen 125 (CA 125) levels
|
|
|
Schizophrenia (MTAG)
|
|
|
Osteoporosis-related phenotypes (MTAG)
|
|
|
Clozapine-induced myocarditis in schizophrenia
|
|
|
Urinary volume
|
|
|
Insulin-related traits (multivariate analysis)
|
|
|
Eczema
|
|
|
Cleft lip with or without cleft palate x maternal periconceptional alcohol use interaction (parent of origin effect)
|
|
|
Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect)
|
|
|
Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect)
|
|
|
Serum folate levels
|
|
|
Serum alpha-fetoprotein levels
|
|
|
Serum carcinoembryonic antigen levels
|
|
|
Serum cancer antigen 15.3 levels
|
|
|
Osteoarthritis of the hand
|
|
|
Leukocyte telomere length
|
|
|
Post bronchodilator percent predicted FEV1 in smoking
|
|
|
Post bronchodilator FEV1/FVC ratio in smoking
|
|
|
Electrocardiogram morphology (amplitude at temporal datapoints)
|
|
|
Thyroid nodules
|
|
|
Thrombocytopenia in coronary artery bypass surgery
|
|
|
Midgestational cytokine/chemokine levels (maternal genetic effect)
|
|
|
Neonatal cytokine/chemokine levels (maternal genetic effect)
|
|
|
Midgestational cytokine/chemokine levels (fetal genetic effect)
|
|
|
Neonatal cytokine/chemokine levels (fetal genetic effect)
|
|
|
Iris color (a* coordinate)
|
|
|
Iris color (L* coordinate)
|
|
|
Iris heterochromicity
|
|
|
Iris color (b* coordinate)
|
|
|
General factor of neuroticism
|
|
|
tricyclic pyrone compound response (IC50)
|
|
|
Confectionary intake
|
|
|
Plasma factor VII activating protease levels
|
|
|
Adverse response to antithyroid drugs in Graves disease
|
|
|
Morning person
|
|
|
Glioblastoma (age-stratified)
|
|
|
Worry/vulnerability (special factor of neuroticism)
|
|
|
Anxiety/tension (special factor of neuroticism)
|
|
|
Vestibular neuritis
|
|
|
Plasma parathyroid hormone levels
|
|
|
Cognitive flexibility
|
|
|
Aspartate aminotransferase levels
|
|
|
Rumination (response to stress)
|
|
|
Brooding (response to stress)
|
|
|
Reflection (response to stress)
|
|
|
3-month functional outcome in ischaemic stroke (modified Rankin score)
|
|
|
3-month functional outcome in non-lacunar ischaemic stroke (modified Rankin score)
|
|
|
3-month functional outcome in lacunar ischaemic stroke (modified Rankin score)
|
|
|
Chronic central serous retinopathy
|
|
|
Neutrophil level response to clozapine in treatment-resistant schizophrenia
|
|
|
Severe aortic features in Marfan syndrome
|
|
|
Progressive supranuclear palsy
|
A movement disease characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.
|
|
Ewing sarcoma
|
A spectrum of malignant tumors, affecting mostly males under age 20, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. These tumors may occur in the soft tissues or the bones. Pain and the presence of a mass are the most common clinical symptoms. -- 2004|A small round cell tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing's sarcoma/peripheral neuroectodermal tumor. It affects mostly males under age 20, and it can occur in soft tissue or bone. Pain and the presence of a mass are the most common clinical symptoms.|A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. There are conspicuous foci of necrosis in association with irregular masses of small, regular, rounded or ovoid cells with very scanty cytoplasm. The tumor occurs usually before the age of 20, about twice as frequently in males as in females. (From Dorland, 27th ed; Stedman, 25th ed)|A spectrum of malignant tumors, affecting mostly males under age 20, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. These tumors may occur in the soft tissues or the bones. Pain and the presence of a mass are the most common clinical symptoms.
|
|
Leisure-time exercise behaviour
|
|
|
Leisure-time exercise behaviour (age-stratified)
|
|
|
Glomerular filtration rate change in heart transplantation
|
|
|
Energy expenditure
|
|
|
Energy intake
|
Total number of calories taken in daily whether ingested or by parenteral routes.
|
|
Femoral neck length
|
|
|
Narrowest width of the femoral neck
|
|
|
Femoral neck section modulus
|
|
|
Alanine aminotransferase levels
|
|
|
cognitive impairment (MMSE score) in Parkinson’s disease
|
|
|
Response to antidepressants (symptom improvement)
|
|
|
Remission after antidepressant treatment in major depression
|
|
|
Shoulder impingement or rotator cuff tear
|
|
|
Shoulder impingement
|
|
|
Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy
|
|
|
Sudden cardiac arrest
|
|
|
Warfarin maintenance dose (adjusted for clinical factors)
|
|
|
Bronchopulmonary dysplasia in preterm infants
|
|
|
Gemcitabine-induced early high-grade neutropenia in pancreatic cancer
|
|
|
Response to dolutegravir (body weight gain)
|
|
|
Cortical volume
|
|
|
Body mass index and systolic blood pressure (bivariate analysis)
|
|
|
Systolic blood pressure and diastolic blood pressure (bivariate analysis)
|
|
|
Body mass index and diastolic blood pressure (bivariate analysis)
|
|
|
Gut microbiota relative abundance (Prevotella)
|
|
|
Gut microbiota relative abundance (Bifidobacterium)
|
|
|
Gut microbiota relative abundance (Bacteroides)
|
|
|
Gut microbiota relative abundance (Streptococcus)
|
|
|
Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae)
|
|
|
Gut microbiota relative abundance (Parabacteroides)
|
|
|
Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae)
|
|
|
Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae)
|
|
|
Gut microbiota relative abundance (Blautia)
|
|
|
Airway obstruction (FEV1/FVC<70%) in never smokers
|
|
|
Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers
|
|
|
Emphysema annual change measurement in smokers (adjusted lung density)
|
|
|
Emphysema annual change measurement in smokers (percent low attenuation area)
|
|
|
Meningococcal C functional antibody titers post childhood immunization
|
|
|
Lipoprotein (a) levels in coronary artery disease (percutaneous coronary intervention)
|
|
|
Hepatitis C (spontaneous viral clearance)
|
|
|
Anti-drug antibodies in autoimmune disease (time to event)
|
|
|
Obsessive-compulsive traits
|
|
|
Mitochondrial DNA copy number (white blood cells)
|
|
|
Mitochondrial DNA copy number
|
|
|
Psychological distress
|
disease cluster belonging to disease group psych
|
|
Breakfast cereal skipping frequency
|
|
|
Breakfast skipping
|
|
|
Kawasaki disease
|
A lymphadenitis characterized by swelling of cervical lymph nodes in infants and young children and inflammation of medium-sized blood vessels located_in body, has_symptom fever, has_symptom congestion of ocular conjunctivae, has_symptom reddening of lips, has_symptom reddening of oral cavity, has_symptom protuberance of tongue papillae and has_symptom edema of extremities.
|
|
Opioid overdose severity score
|
|
|
Multisite chronic pain
|
|
|
Medial temporal lobe substructure volumes
|
|
|
Glomerular filtration rate in type 2 diabetes
|
|
|
Glomerular filtration rate in diabetes
|
|
|
Early diabetic kidney disease in type 2 diabetes
|
|
|
Diabetic kidney disease in type 2 diabetes
|
|
|
Osteoarthritis
|
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
|
|
Osteoarthritis (hip)
|
|
|
Osteoarthritis of the hip or knee
|
|
|
Gut microbiota relative abundance (Sutterella)
|
|
|
Gut microbiota relative abundance (Faecalibacterium)
|
|
|
Gut microbiota relative abundance (Oscillospira)
|
|
|
Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae)
|
|
|
Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales)
|
|
|
Gut microbiota relative abundance (Eubacterium belonging to family Erysipelotrichaceae)
|
|
|
Gut microbiota alpha diversity (Chao1 index)
|
|
|
Gut microbiota alpha diversity (PD_whole_tree index)
|
|
|
Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae)
|
|
|
Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae)
|
|
|
Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales)
|
|
|
Gut microbiota alpha diversity (Shannon index)
|
|
|
Gut microbiota relative abundance (Coprococcus)
|
|
|
Gut microbiota relative abundance (Dorea)
|
|
|
Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae)
|
|
|
Gut microbiota beta diversity (weighted UniFrac distance)
|
|
|
Rapid automised naming of pictures
|
|
|
Rapid automised naming of digits
|
|
|
Short-term memory (digit-span task)
|
|
|
Non-word reading
|
non-word reading is the complex cognitive process of decoding symbols in order to derive that they do not form meaningful words
|
|
Word spelling
|
|
|
Phoneme awareness
|
|
|
Word reading
|
word reading is the complex cognitive process of decoding symbols in order to construct or derive meaningful words
|
|
Blood cell traits (multivariate analysis)
|
|
|
Thyroid stimulating hormone levels
|
|
|
Bitter non-alcoholic beverage consumption
|
|
|
Bitter alcoholic beverage consumption
|
|
|
Tea consumption
|
|
|
Myeloproliferative neoplasms
|
disease cluster belonging to disease group cancer
|
|
Non-HDL cholesterol levels
|
|
|
Walking pace
|
|
|
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)
|
|
|
Severe skin toxicity response to cetuximab in colorectal cancer
|
|
|
Sedentary behaviour duration
|
|
|
Physical activity (walking duration)
|
|
|
Physical activity (moderate intensity activity duration)
|
|
|
Physical activity (overall physical activity time)
|
|
|
Thiopurine-induced early leukopenia in Crohn's disease
|
|
|
Fasting blood proinsulin levels
|
|
|
Insulinogenic index
|
|
|
Insulin disposition index
|
|
|
Proinsulin levels (late-phase conversion)
|
|
|
Proinsulin levels (early-phase conversion)
|
|
|
Fasting blood glucose
|
|
|
Hemoglobin A1c levels
|
|
|
Coffee consumption (cups per day)
|
|
|
Cortical surface area
|
disease cluster belonging to disease group neurological
|
|
Adverse response to chemotherapy (amenorrhea) in breast cancer
|
|
|
Carbamazepine-induced reaction with eosinophilia and systemic symptoms
|
|
|
Carbamazepine-induced serious cutaneous adverse reaction
|
|
|
Annualised percent change of cerebrospinal fluid AB1-42 levels
|
|
|
Serum oxytocin levels
|
|
|
Order dimension in obsessive compulsive disorder
|
|
|
Sensation seeking
|
|
|
Lack of perseverance
|
|
|
Impulsivity
|
|
|
Impulsivity (attentional)
|
|
|
Lack of premeditation
|
|
|
Positive urgency
|
|
|
Impulsivity (motor)
|
|
|
Negative urgency
|
|
|
Impulsivity (non-planning)
|
|
|
Drug experimentation measurement
|
|
|
Type 2 diabetes nephropathy
|
Diabetic nephropathy is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. In type 2 diabetes hyperglycaemia starts after the forties, usually when the kidneys have already suffered the long‐term consequences of ageing and of other recognized promoters of chronic renal injury such as arterial hypertension, obesity, dyslipidaemia, and smoking.
|
|
Type 2 diabetes nephropathy including microalbuminuria
|
|
|
Anorexia nervosa
|
An eating disorder characterized by refusal to maintain a healthy body weight, and an obsessive fear of gaining weight due to a distorted self image.
|
|
Thyrotoxic periodic paralysis
|
Thyrotoxic periodic paralysis (TPP) is a rare neurological disease characterized by recurrent episodes of paralysis and hypokalemia during a thyrotoxic state.
|
|
Keratoconus
|
A corneal disease characterized by structural changes within the cornea causing it to thin and change, leading to a protruding conical shape.
|
|
Body fat percentage and type 2 diabetes (pairwise)
|
|
|
Body mass index and HDL-C (pairwise)
|
|
|
Body fat percentage and triglycerides (pairwise)
|
|
|
Body fat percentage and HDL-C (pairwise)
|
|
|
Body fat percentage and fasting glucose (pairwise)
|
|
|
Body fat percentage and LDL-C (pairwise)
|
|
|
Body fat percentage and fasting insulin (pairwise)
|
|
|
Body fat percentage and coronary artery disease (pairwise)
|
|
|
Body mass index and LDL-C (pairwise)
|
|
|
Body mass index and triglycerides (pairwise)
|
|
|
Body mass index and fasting insulin (pairwise)
|
|
|
Body mass index and fasting glucose (pairwise)
|
|
|
Left–right brain asymmetry
|
|
|
Rotator cuff injury
|
|
|
Body mass index and type 2 diabetes (pairwise)
|
|
|
Waist-hip ratio and HDL-C (pairwise)
|
|
|
Waist-hip ratio and LDL-C (pairwise)
|
|
|
Waist-hip ratio and triglycerides (pairwise)
|
|
|
Waist-hip ratio and systolic blood pressure (pairwise)
|
|
|
Waist-hip ratio and coronary artery disease (pairwise)
|
|
|
Body mass index and systole blood pressure (pairwise)
|
|
|
Body mass index and coronary artery disease (pairwise)
|
|
|
Waist-hip ratio and type 2 diabetes (pairwise)
|
|
|
Odorant perception
|
|
|
Drug-induced liver injury (isoniazid-containing anti-tuberculosis drugs)
|
|
|
Liver fibrogenesis (alpha smooth muscle actin levels)
|
|
|
Liver fibrosis (total hepatic collagen content)
|
|
|
Myeloperoxidase-DNA complexes
|
|
|
Urinary albumin excretion
|
disease cluster belonging to disease group metabolic
|
|
T-Cell Immunoglobulin and Mucin domain 1 levels
|
|
|
Ambidextrousness
|
|
|
Left-handedness
|
|
|
Cognitive performance in schizophrenia or bipolar disorder
|
|
|
Depression in multiple sclerosis (pre-diagnosis)
|
|
|
Depression in multiple sclerosis (post-diagnosis)
|
|
|
Depression in multiple sclerosis
|
|
|
Shigella-associated diarrhea
|
|
|
Systolic blood pressure (education interaction)
|
|
|
Diastolic blood pressure (education interaction)
|
|
|
Central serous retinopathy
|
|
|
Skeletal muscle index
|
|
|
Asthma (moderate or severe)
|
|
|
Fulminant type 1 diabetes
|
|
|
Podoconiosis
|
|
|
Dilated cardiomyopathy
|
An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently.|A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.|decreased function of the heart associated with cardiac enlargement and congestive heart failure
|
|
Postherpetic neuralgia
|
|
|
Chronic pain
|
Persistent pain, usually defined as pain that has laster longer than 3 to 6 months.
|
|
Hypo-HDL-cholesterolemia
|
|
|
Hypertrophic cardiomyopathy (sarcomere positive)
|
|
|
Hypertrophic cardiomyopathy
|
A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).|A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.
|
|
Hypertrophic cardiomyopathy (sarcomere negative)
|
|
|
Cervical high-risk human papilloma virus infection (persistent)
|
|
|
Cervical high-risk human papilloma virus infection
|
|
|
Psoriasis
|
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
|
|
Pancreatic ductal adenocarcinoma x smoking interaction
|
|
|
Low hand grip strength (60 years and older) (EWGSOP)
|
|
|
Low hand grip strength (60 years and older) (FNIH)
|
|
|
Estrone-3-glucuronide levels
|
|
|
Chronic lymphocytic leukemia (time to first treatment)
|
|
|
smoking initiation in schizophrenia
|
|
|
Cigarettes smoked per day in Schizophrenia
|
|
|
Childhood asthma exacerbations in long-acting beta2-agonist treatment
|
|
|
Vegetable consumption
|
|
|
Rocuronium dose requirement in breast cancer surgery
|
|
|
Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction)
|
|
|
Estimated glomerular filtration rate (creatinine, Rapid3)
|
|
|
Estimated glomerular filtration rate (creatinine, CKDi25)
|
|
|
Metamizole-induced agranulocytosis or neutropenia
|
|
|
Metamizole-induced agranulocytosis
|
|
|
Type 1 diabetes (age at diagnosis)
|
|
|
Orofacial clefts
|
disease cluster belonging to disease group developmental
|
|
Aortic vascular smooth muscle cell calcification in response to osteogenic stimuli
|
|
|
Aortic vascular smooth muscle cell proliferation in response to IL-1 beta
|
|
|
Body composition traits
|
|
|
Serum type 1 collagen metabolite levels
|
|
|
Serum total cholesterol levels
|
|
|
Type 2 diabetes or prostate cancer (pleiotropy)
|
|
|
Pediatric central nervous system tumors (early onset)(pleiotropy)
|
|
|
Pediatric central nervous system tumors (late onset)(pleiotropy)
|
|
|
Pediatric central nervous system tumors (pleiotropy)
|
|
|
Response to immune checkpoint inhibitors in melanoma (immune-related adverse events)
|
|
|
Tuberculosis susceptibility in HIV infection
|
|
|
Waist-to-hip ratio adjusted for BMI
|
|
|
Bell's palsy
|
A facial paralysis resulting from dysfunction in the cranial nerve VII (facial nerve).
|
|
Skin reflectance (Melanin index)
|
|
|
Eye morphology
|
|
|
Chin morphology
|
|
|
Nose morphology
|
|
|
Achilles tendon injury
|
|
|
Tinnitus
|
Tinnitus is an auditory perception that can be described as the experience of sound, in the ear or in the head, in the absence of external acoustic stimulation.
|
|
RR interval (heart rate)
|
disease cluster belonging to disease group cardiovascular
|
|
Asthma (adult onset)
|
|
|
Asthma (childhood onset)
|
disease cluster belonging to disease group immune
|
|
Thyroglobulin plasma levels
|
|
|
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy)
|
|
|
Chronic obstructive pulmonary disease or resting heart rate (pleiotropy)
|
|
|
Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy)
|
|
|
Tinnitus in cisplatin-treated testicular cancer
|
|
|
Voxel-wise structural brain imaging measurements
|
|
|
Calcaneus stiffness index
|
|
|
Visceral fat
|
|
|
Facial attractiveness (male raters)
|
|
|
Facial attractiveness (female raters)
|
|
|
Peginterferon alfa-2a treatment response in chronic hepatitis B infection
|
|
|
Alcohol use disorder
|
|
|
Executive function (trail making test B)
|
|
|
perceptual and visual search speed (trail making test A) (age interaction)
|
|
|
Depression in smokers
|
|
|
Ankylosing spondylitis
|
A bone inflammation disease that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.
|
|
Asthma onset (childhood vs adult)
|
|
|
Postoperative survival time in hepatocellular carcinoma
|
|
|
Lumbar spine bone mineral density (trabecular)
|
|
|
Lumbar spine bone mineral density (integral)
|
|
|
Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect)
|
|
|
Estimated glomerular filtration rate after 5 years in renal transplantation (recipient effect)
|
|
|
Estimated glomerular filtration rate after 5 years in renal transplantation (donor effect)
|
|
|
Estimated glomerular filtration rate change in renal transplantation (recipient effect)
|
|
|
Estimated glomerular filtration rate change in renal transplantation (donor effect)
|
|
|
Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect)
|
|
|
Diarrhoea-associated Entamoeba histolytica infection
|
|
|
Carotid plaque maximum area
|
|
|
Maximum stenosis
|
|
|
Sum of carotid plaque area
|
|
|
Mean area of carotid plaque
|
|
|
Mean degree of stenosis
|
|
|
Sum of stenosis
|
|
|
Response to hepatitis B vaccine
|
|
|
Coronary artery calcification
|
Calcification, that is, pathological deposition of calcium salts, affecting the coronary arteries.
|
|
Cardiovascular disease in type 2 diabetes
|
|
|
Adiponectin levels x Mediterranean diet adherence interaction
|
|
|
Visceral fat, circulating phospholipid PC(16:0/2:0) and white matter microstructure (shared variance)
|
|
|
BMI x environmental factors (including physical activity) interaction
|
|
|
BMI x environmental factors (excluding physical activity) interaction
|
|
|
Fever and diarrhea in mesalamine-treated irritable bowel disease
|
|
|
Facial morphology traits (63 three-dimensional facial segments)
|
|
|
Diabetic peripheral neuropathy in type 2 diabetes
|
|
|
Sick sinus syndrome
|
Xref MGI.
|
|
Cardiovascular event in colchicine-treated recent myocardial infarction (time to event)
|
|
|
Relapse in treatment-naive multiple sclerosis (time to event)
|
|
|
Oxidized LDL cholesterol levels
|
|
|
Breast cancer in BRCA2 mutation carriers
|
|
|
Brain-derived neurotrophic factor levels
|
|
|
Extranodal natural killer T-cell lymphoma (nasal type)
|
|
|
Childhood onset ulcerative colitis
|
|
|
Macular thickness
|
|
|
Response to cognitive-behavioural therapy in anxiety and major depressive disorders
|
|
|
Response to cognitive-behavioural therapy in anxiety disorder
|
|
|
Response to cognitive-behavioural therapy in major depressive disorder
|
|
|
Fragile X syndrome
|
A neurodegenerative disease that is characterized by moderate to severe mental retardation, macroorchidism, and distinct facial features, including long face, large ears, and prominent jaw, and has_material_basis_in a loss of FMR1 function.
|
|
Daytime nap
|
|
|
Mental health related quality of life
|
|
|
Physical health related quality of life
|
|
|
Rapid response to perioperative phenylephrine (change in mean arterial pressure)
|
|
|
Rapid response to perioperative phenylephrine (change in systolic blood pressure)
|
|
|
Glaucoma (low intraocular pressure)
|
|
|
Kleine-Levin syndrome
|
A recurrent hypersomnia that is characterized by recurring periods of excessive amounts of sleep and altered behavior.
|
|
Low myopia
|
|
|
Mitochondrial heteroplasmy measurement
|
|
|
ghrelin levels
|
|
|
Low myopia vs hyperopia
|
|
|
HOMA-B (corrected for HOMA-IR)
|
|
|
Lacunar stroke
|
|
|
Persistent hepatitis B virus infection
|
|
|
Chronic hepatitis B infection vs asymptomatic persistence
|
|
|
Hepatitis B virus-related hepatocellular carcinoma vs chronic hepatitis B infection
|
|
|
Hepatitis B virus-related hepatocellular carcinoma vs hepatitis B virus-related decompensated cirrhosis
|
|
|
DDT metabolite (p,p'-DDE levels)
|
|
|
Hyperopia
|
|
|
Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder
|
|
|
HDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder
|
|
|
LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder
|
|
|
Total cholesterol levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder
|
|
|
Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder
|
|
|
BMI x SSRI levels interaction in schizophrenia or bipolar disorder
|
|
|
HDL levels x SSRI levels interaction in schizophrenia or bipolar disorder
|
|
|
LDL levels x SSRI levels interaction in schizophrenia or bipolar disorder
|
|
|
Total cholesterol levels x SSRI levels interaction in schizophrenia or bipolar disorder
|
|
|
BMI x SSRI defined daily dose interaction in schizophrenia or bipolar disorder
|
|
|
HDL levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder
|
|
|
LDL levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder
|
|
|
HDL levels x fish oil supplementation interaction (2df)
|
|
|
Total cholesterol levels x fish oil supplementation interaction (2df)
|
|
|
HDL levels x fish oil supplementation interaction (1df)
|
|
|
Total cholesterol levels x fish oil supplementation interaction (1df)
|
|
|
Triglyceride levels x fish oil supplementation interaction (1df)
|
|
|
LDL levels x fish oil supplementation interaction (1df)
|
|
|
Triglyceride levels x fish oil supplementation interaction (2df)
|
|
|
LDL levels x fish oil supplementation interaction (2df)
|
|
|
Total cholesterol levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder
|
|
|
Clostridioides difficle infection in antibiotics-users
|
|
|
Clostridioides difficle infection
|
|
|
Obstructive sleep apnea
|
A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.
|
|
Obstructive sleep apnea (BMI adjusted)
|
|
|
Inflammatory skin disease
|
|
|
Blood pressure (smoking interaction)
|
|
|
Superior frontal gyrus grey matter volume
|
|
|
White matter microstructure (global fractional anisotropy)
|
|
|
Conduct disorder (symptom count)
|
|
|
Conduct disorder
|
A specific developmental disorder marked by a pattern of repetitive behavior wherein the rights of others or social norms are violated.
|
|
Clubfoot
|
OMIM mapping confirmed by DO. [SN].
|
|
Response to radiotherapy in cancer (late toxicity)
|
|
|
Renal function and chronic kidney disease
|
disease cluster belonging to disease group renal
|
|
Chronic hepatitis B infection
|
INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
|
|
Glycated hemoglobin levels
|
|
|
Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)
|
|
|
Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)
|
|
|
Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
|
|
|
Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)
|
|
|
Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)
|
|
|
Toenail selenium levels
|
|
|
Blood and toenail selenium levels
|
|
|
Sepsis from pneumonia (survival)
|
|
|
Vitamin B levels in ischemic stroke
|
|
|
Electroencephalogram traits
|
|
|
Resting oxygen saturation in chronic osbtructive pulmonary disease (pulse oxymetry)
|
|
|
Mitochondrial DNA levels
|
|
|
Acute lymphoblastic leukemia (childhood)
|
disease cluster belonging to disease group cancer
|
|
Glucose homeostasis traits
|
|
|
Asymmetrical dimethylarginine levels
|
|
|
Symmetrical dimethylarginine levels
|
|
|
Suicide attempts in depression or bipolar disorder
|
|
|
Asthma (corticosteroid response)
|
|
|
CD4:CD8 lymphocyte ratio
|
|
|
CD8-positive T-lymphocyte count
|
|
|
Esophageal adenocarcinoma
|
Esophageal adenocarcinoma (EAC) is a sub-type of esophageal carcinoma (EC; see this term) affecting the glandular cells of the lower esophagus at the junction with the stomach.
|
|
Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined)
|
|
|
Barrett's esophagus
|
Metaplasia of the lower esophagus that is characterized by replacement of squamous epithelium with columnar epithelium, occurs especially as a result of chronic gastroesophageal reflux, and is associated with an increased risk for esophageal carcinoma.
|
|
Longevity (90 years and older)
|
|
|
Serum IgA levels
|
|
|
Pulmonary artery enlargement and chronic obstructive pulmonary disease
|
|
|
Pulmonary artery enlargement in chronic obstructive pulmonary disease
|
|
|
Autism spectrum disorder-related traits
|
|
|
Laryngeal squamous cell carcinoma
|
A laryngeal carcinoma that has_material_basis_in squamous cells.
|
|
Age-related cataracts
|
|
|
Age-related cataracts (age at onset)
|
|
|
Longevity (85 years and older)
|
|
|
Restless legs syndrome
|
A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them.
|
|
Breast cancer (survival)
|
|
|
Hemoglobin A2 levels in sickle cell anemia
|
|
|
Lipid traits
|
|
|
Hearing function
|
|
|
Osteoarthritis biomarkers
|
|
|
Obesity-related traits
|
disease cluster belonging to disease group metabolic
|
|
Fibrinogen
|
disease cluster belonging to disease group metabolic
|
|
Autism
|
A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-IV)|An autism spectrum disease that is a disorder of neural development characterized by impaired social interaction and communication, and by restricted and repetitive behavior observed in children before a child is three years old.
|
|
Glomerular filtration rate
|
measurement of the flow rate of filtered fluid through the kidney, calculated either by comparative measurements of substances in the blood and urine, or estimated from a blood test
|
|
Thrombin generation potential phenotypes
|
|
|
Nicotine use
|
|
|
Illicit drug use
|
|
|
Behavioural disinhibition (generation interaction)
|
|
|
Non-substance related behavioral disinhibition
|
|
|
Glycemic traits (pregnancy)
|
|
|
C-reactive protein levels
|
|
|
Pulse pressure (alcohol consumption interaction)
|
|
|
Systolic blood pressure (alcohol consumption interaction)
|
|
|
Diastolic blood pressure (alcohol consumption interaction)
|
|
|
Mean arterial pressure (alcohol consumption interaction)
|
|
|
Acne (severe)
|
|
|
Autoimmune hepatitis type-1
|
|
|
Pulse pressure in young-onset hypertension
|
|
|
Birth length
|
|
|
Infant length
|
|
|
Alzheimer's disease (age of onset)
|
|
|
Anger
|
|
|
Serum thyroid-stimulating hormone levels
|
|
|
Esophageal cancer
|
A gastrointestinal system cancer that is located_in the esophagus.
|
|
Medication adherence in chronic diseases
|
|
|
Episodic memory
|
Type of declarative memory, consisting of personal memory in contrast to general knowledge.
|
|
Urinary bladder cancer
|
An urinary system cancer that results_in malignant growth located_in the urinary bladder.
|
|
Plasma homocysteine levels (post-methionine load test)
|
|
|
Red blood cell traits
|
|
|
Morphine dose requirement in tonsillectomy and adenoidectomy surgery
|
|
|
Chronic obstructive pulmonary disease (moderate to severe)
|
|
|
Chronic obstructive pulmonary disease (severe)
|
|
|
Preschool internalizing problems
|
|
|
Irritable bowel syndrome
|
A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.|A syndrome that is a functional bowel disorder characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.
|
|
Asthma (sex interaction)
|
|
|
Urinary albumin excretion rate in type 1 diabetes
|
|
|
Breast cancer (early onset)
|
|
|
Chronic periodontitis
|
|
|
Blood pressure (anthropometric measures interaction)
|
|
|
Blood pressure
|
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
|
|
Osteoarthritis (hand, severe)
|
|
|
IgE levels
|
|
|
Response to inhaled corticosteroid treatment in asthma (change in FEV1)
|
|
|
Antinuclear antibody levels
|
|
|
Response to statin therapy
|
disease cluster belonging to disease group pharmacogenomic
|
|
Response to antipsychotic therapy (extrapyramidal side effects)
|
disease cluster belonging to disease group pharmacogenomic
|
|
Obsessive-compulsive disorder
|
An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
|
|
Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced)
|
|
|
Creatine kinase levels in statin users
|
|
|
Breastfeeding duration
|
|
|
Pneumoconiosis in silica exposure
|
|
|
Iron status biomarkers
|
|
|
Soluble leptin receptor levels
|
|
|
Inflammatory biomarkers
|
|
|
Cervical artery dissection
|
|
|
Fetal hemoglobin levels in sickle cell anemia
|
|
|
Airway responsiveness in chronic obstructive pulmonary disease
|
|
|
Inflammatory biomarkers in Kawasaki disease
|
|
|
Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)
|
|
|
Free thyroxine concentration
|
|
|
Thyroid peroxidase antibody positivity
|
|
|
Pulmonary emphysema
|
|
|
Methotrexate clearance (acute lymphoblastic leukemia)
|
|
|
IgA levels
|
|
|
Lupus nephritis in systemic lupus erythematosus
|
|
|
Osteoprotegerin levels
|
|
|
Response to antipsychotic treatment
|
disease cluster belonging to disease group pharmacogenomic
|
|
Exfoliation glaucoma or exfoliation syndrome
|
|
|
Response to taxane treatment (paclitaxel)
|
|
|
Response to taxane treatment (docetaxel)
|
|
|
Non-alcoholic fatty liver disease histology (other)
|
|
|
Breast cancer (menopausal hormone therapy interaction)
|
|
|
Lobular breast cancer (menopausal hormone therapy interaction)
|
|
|
Major depressive disorder
|
An endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities.
|
|
Type 2 diabetes (young onset) and obesity
|
|
|
Age-related hearing impairment
|
Age-related hearing impairment is characterized by a symmetric sensorineural hearing loss that is most pronounced in the high frequencies. Age of onset, progression, and severity of age-related hearing impairment (ARHI) show great variation in the population, but with a demonstrable increased prevalence in males.
|
|
Hippocampal sclerosis of aging
|
age-related neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus
|
|
Openness
|
|
|
Conscientiousness
|
|
|
Peripheral artery disease
|
An artery disease that is characterized by build up of plaque in the arteries that carry blood to your head, organs, and limbs.
|
|
Cognitive decline (age-related)
|
|
|
Personality traits in bipolar disorder
|
|
|
Drug-induced torsades de pointes
|
|
|
Alcohol dependence (age at onset)
|
|
|
Hypospadias
|
A physical disorder characterized by an abnormally placed urethral opening on the underside of the penis or on the perineum.
|
|
Interferon alpha levels in systemic lupus erythematosus
|
|
|
Hepatic lipid content in extreme obesity
|
|
|
Bilirubin levels in extreme obesity
|
|
|
Chronic mucus hypersecretion
|
|
|
Amyloid A serum levels
|
|
|
Plasma amyloid beta peptide concentrations (ABx-40)
|
|
|
Plasma amyloid beta peptide concentrations (ABx-42)
|
|
|
Amyotrophic lateral sclerosis or frontotemporal dementia
|
|
|
Vitiligo
|
A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.
|
|
Fractional exhaled nitric oxide (childhood)
|
|
|
Bipolar disorder (body mass index interaction)
|
|
|
Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity)
|
|
|
Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels)
|
|
|
Response to diuretic therapy in hypertension
|
|
|
Thyroid peroxidase antibody levels
|
|
|
Kidney function decline traits
|
|
|
Immune response to measles-mumps-rubella vaccine
|
|
|
Kashin-Beck disease
|
|
|
Methotrexate pharmacokinetics (acute lymphoblastic leukemia)
|
|
|
Enteric fever
|
|
|
Cerebrospinal fluid levels of Alzheimer's disease-related proteins
|
|
|
Generalized epilepsy
|
disease cluster belonging to disease group other
|
|
Apolipoprotein Levels
|
|
|
Cholesterol and Triglycerides
|
|
|
PCA3 expression level
|
|
|
Sleep-related phenotypes
|
|
|
Otitis media (chronic/recurrent)
|
|
|
Infantile hypertrophic pyloric stenosis
|
This condition is caused by diffuse hypertrophy and hyperplasia of the smooth muscle of the antrum of the stomach and pylorus. It usually occurs in infants aged 2-8 weeks. The pyloric muscle hypertrophy results in narrowing of the pyloric canal, which can then become easily obstructed. Genetic studies have identified susceptibility loci for infantile hypertrophic pyloric stenosis (IHPS) and molecular studies have concluded that smooth muscle cells are not properly innervated in this condition.
|
|
End-stage renal disease in Type 1 diabetics
|
|
|
Bone mineral density (paediatric, upper limb)
|
|
|
Bone mineral density (paediatric, lower limb)
|
|
|
Bone mineral density (paediatric, total body less head)
|
|
|
Bone mineral density (paediatric, skull)
|
|
|
Acute anterior uveitis (with or without ankylosing spondylitis)
|
|
|
Colorectal cancer (calcium intake interaction)
|
|
|
Myopia (pathological)
|
disease cluster belonging to disease group vision
|
|
Parent of origin effect on language impairment (paternal)
|
|
|
Reading disability or specific language impairment (pleiotropy)
|
|
|
Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy)
|
|
|
Blood pressure (age interaction)
|
|
|
Opioid sensitivity
|
|
|
Response to temozolomide
|
|
|
Birth weight
|
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
|
|
Psychosis (atypical)
|
|
|
Height adjusted BMI
|
|
|
Homocysteine levels
|
|
|
Recombination measurement
|
|
|
Puberty onset (genital enlargement)
|
|
|
Puberty onset (breast development)
|
|
|
Puberty onset
|
disease cluster belonging to disease group developmental
|
|
Response to cytidine analogues (gemcitabine)
|
|
|
Response to cytadine analogues (cytosine arabinoside)
|
|
|
Ossification of the posterior longitudinal ligament of the spine
|
A disorder characterized by benign depositions of calcium in the posterior longitudinal ligament. Signs and symptoms result from the compression of nerve roots and include motor and sensory disturbances in the lower and upper extremities, and pain in the neck and arms.
|
|
Electrocardiographic traits
|
disease cluster belonging to disease group cardiovascular
|
|
Bronchopulmonary dysplasia
|
Bronchopulmonary dysplasia is a chronic respiratory disease that results from complications related to lung injury during the treatment of respiratory distress syndrome in low-birth-weight premature infants or from abnormal lung development in older infants. Clinical signs are tachypnea, tachycardia and signs of respiratory distress such as intercostal recession, grunting and nasal flaring.
|
|
Recombination measurement (females)
|
|
|
Recombination measurement (males)
|
|
|
Cocaine dependence
|
A drug dependence that is a psychological dependency on the regular use of cocaine.
|
|
Narcolepsy
|
A sleep disorder that involves an excessive urge to sleep at inappropriate times, such as while at work.
|
|
Schizophrenia or bipolar disorder
|
|
|
Response to statins (LDL cholesterol change)
|
|
|
Glioma (high-grade)
|
disease cluster belonging to disease group cancer
|
|
Fibrinogen levels (smoking status, alcohol consumption or body mass index interaction)
|
|
|
Diabetic retinopathy in type 2 diabetes
|
disease cluster belonging to disease group renal
|
|
Crohn's disease-related phenotypes
|
|
|
Airway wall thickness
|
|
|
Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection
|
|
|
Neuroblastoma
|
A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation.|A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)|A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH).
|
|
Cystic fibrosis-related diabetes
|
|
|
Social autistic-like traits
|
|
|
Androgen levels
|
disease cluster belonging to disease group other
|
|
Response to platinum-based chemotherapy in non-small-cell lung cancer
|
|
|
Smoking behavior
|
Inhaling and exhaling the smoke of tobacco or something similar to tobacco.
|
|
C-reactive protein
|
disease cluster belonging to disease group immune
|
|
Adverse response to radiation therapy
|
|
|
Carotid plaque burden (smoking interaction)
|
|
|
Paclitaxel-induced neuropathy
|
|
|
Serum lipase activity
|
|
|
High serum lipase activity
|
|
|
Memory performance
|
Is a quantification of a subject's activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. Memory performance is typically assessed by some clinical memory test and is used in the diagnosis of diseases such as Alzheimer's disease.
|
|
Cerebrospinal AB1-42 levels in Alzheimer's disease dementia
|
|
|
Tourette's syndrome or obsessive-compulsive disorder
|
|
|
Asthma and hay fever
|
|
|
Conotruncal heart defects
|
|
|
IgE levels in asthmatics
|
|
|
IgE levels in asthmatics (D.p. specific)
|
|
|
IgE levels in asthmatics (D.f. specific)
|
|
|
Obesity
|
An eating-related disorder in which excess body fat has accumulated to such an extent that health may be negatively affected. It is commonly defined as a body mass index (weight divided by height squared) of 30 kg/m2 or higher.|A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
|
|
Chronic hepatitis C infection
|
disease cluster belonging to disease group infection
|
|
Hepatitis B vaccine response
|
|
|
Pain
|
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
|
|
Lung function (forced vital capacity)
|
|
|
AIDS progression
|
disease cluster belonging to disease group infection
|
|
Allergic dermatitis (nickel)
|
|
|
Lung Cancer (DNA repair capacity)
|
|
|
Sleep time
|
measurement of the time at which sleep begins
|
|
Sleep quality
|
self-reported quality of sleeping
|
|
Epithelial ovarian cancer
|
disease cluster belonging to disease group cancer
|
|
Cleft plate (environmental tobacco smoke interaction)
|
|
|
Clozapine-induced cytotoxicity
|
|
|
Stroke (ischemic)
|
|
|
Beta-2 microglubulin plasma levels
|
|
|
Serum dimethylarginine levels (asymmetric/symetric ratio)
|
|
|
Serum vitamin D-binding protein levels
|
|
|
Rheumatoid arthritis (ACPA-negative)
|
|
|
Mathematical ability in children with dyslexia
|
|
|
Body mass (lean)
|
disease cluster belonging to disease group metabolic
|
|
Cardiac Troponin-T levels
|
|
|
Glaucoma (primary angle closure)
|
|
|
Exhaled carbon monoxide levels
|
|
|
Asthma or chronic obstructive pulmonary disease
|
|
|
Follicular lymphoma
|
A non-Hodgkin lymphoma that is characterized as an indolent non-Hodgkin's lymphoma and has_material_basis_in follicle center B-cells (centrocytes and centroblasts).
|
|
Body mass index (change over time)
|
|
|
Lipoprotein (a) - cholesterol levels
|
|
|
Serum VEGFR2 concentration
|
|
|
Fractional exhaled nitric oxide levels
|
|
|
Pulmonary function in asthmatics
|
|
|
Metabolite levels
|
|
|
Red wine liking
|
|
|
White wine liking
|
|
|
Alzheimer's disease in APOE e4- carriers
|
|
|
Alzheimer's disease in APOE e4+ carriers
|
|
|
Survival in rectal cancer
|
|
|
Survival in microsatellite instability low/stable colorectal cancer
|
|
|
Schizophrenia (inflammation and infection response interaction)
|
|
|
Bipolar disorder (inflammation and infection response interaction)
|
|
|
Sitting height ratio
|
|
|
Spontaneous preterm birth (preterm birth)
|
|
|
Spontaneous preterm birth (preterm delivery)
|
|
|
Insulin resistance/response
|
|
|
Underweight status
|
|
|
Overweight status
|
|
|
Schizophrenia (treatment resistant)
|
|
|
Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)
|
|
|
Bladder cancer (smoking interaction)
|
|
|
Cotinine glucuronidation
|
|
|
Nicotine glucouronidation
|
|
|
Response to radiotherapy in prostate cancer (toxicity)
|
|
|
Mammographic density (dense area)
|
|
|
Mammographic density (non-dense area)
|
|
|
Percent mammographic density
|
|
|
Left inferior lateral ventricle volume (Cerebrospinal fluid biomarker status interaction)
|
|
|
Urgency urinary incontinence
|
|
|
White matter integrity
|
White matter integrity is a measure of brain white matter using brain imaging and quantification techniques. White matter integrity is used as a measure of CNS function.
|
|
White matter integrity (bipolar disorder risk interaction)
|
|
|
Cytomegalovirus antibody response
|
|
|
Thoracic aortic aneurysms and dissections
|
|
|
Protein biomarker
|
|
|
Lipid metabolism phenotypes
|
|
|
Acute lymphoblastic leukemia (B-cell precursor)
|
|
|
Functional impairment in major depressive disorder, bipolar disorder and schizophrenia
|
|
|
Myopia (severe)
|
|
|
Febrile seizures
|
Febrile seizures are convulsions induced by a fever in infants or small children and are generally characterized by loss of consciousness and tonic-clonic movements. Most febrile seizures last a minute or two.
|
|
Febrile seizures (MMR vaccine-unrelated)
|
|
|
Febrile seizures (MMR vaccine-related)
|
|
|
Mesial temporal lobe epilepsy with hippocampal sclerosis
|
|
|
Personality dimensions
|
|
|
Elevated serum carcinoembryonic antigen levels
|
|
|
Binge eating behaviour in bipolar disorder
|
|
|
Binge eating behaviour and bipolar disorder
|
|
|
Epilepsy
|
A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.|A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy) (MeSH).|A disorder characterized by recurrent seizures
|
|
Lung cancer (smoking interaction)
|
|
|
Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma)
|
|
|
Complement C3 and C4 levels
|
|
|
Anti-saccade response
|
|
|
P wave duration
|
measurement of the time from start to finish of the P wave, in the electrocardiograph illustrating the initial deflection of the cardiac cycle, representing the excitation of the atria.
|
|
PR segment duration
|
|
|
Spine bone size
|
Spine bone size is a measurement of the dimensions of the spine.
|
|
Response to methotrexate in juvenile idiopathic arthritis
|
|
|
Cognitive decline
|
|
|
Systemic lupus erythematosus and Systemic sclerosis
|
|
|
Response to methotrexate in rheumatoid arthritis
|
|
|
Airway hyperresponsiveness
|
one of the primary characteristics of asthma, characterised by easily triggered increased airway smooth muscle contractility
|
|
Heschl's gyrus morphology
|
|
|
Very long-chain saturated fatty acid levels (fatty acid 20:0)
|
|
|
Very long-chain saturated fatty acid levels (fatty acid 22:0)
|
|
|
Very long-chain saturated fatty acid levels (fatty acid 24:0)
|
|
|
Age-related nuclear cataracts
|
|
|
Acute lymphoblastic leukemia (adolescents and young adults)
|
|
|
Plasma renin activity levels
|
|
|
Number of children (6+ vs. 0 or 1)
|
|
|
Number of children
|
|
|
Antibody level in response to infection
|
|
|
Number of pregnancies
|
|
|
Alloimmunization response to red blood cell transfusion in sickle cell anemia
|
|
|
Urate levels in lean individuals
|
|
|
Urate levels (BMI interaction)
|
|
|
Urate levels in overweight individuals
|
|
|
Urate levels in obese individuals
|
|
|
Maximal oxygen uptake response
|
|
|
Colorectal cancer (aspirin and/or NSAID use interaction)
|
|
|
HIV-1 susceptibility
|
|
|
Disease-free survival in breast cancer
|
|
|
Parkinson disease and lewy body pathology
|
|
|
Response to platinum-based chemotherapy (carboplatin)
|
|
|
Response to platinum-based chemotherapy (cisplatin)
|
|
|
Reading and spelling
|
|
|
Non-word repetition
|
|
|
Job-related exhaustion
|
|
|
Body mass index (SNP x SNP interaction)
|
|
|
Phosphorus levels
|
|
|
Eosinophilic esophagitis (pediatric)
|
disease cluster belonging to disease group other
|
|
Factor VIII levels
|
|
|
Factor VII levels
|
disease cluster belonging to disease group hematological
|
|
vWF levels
|
|
|
Bipolar disorder (mania)
|
|
|
Cannabis dependence
|
A drug dependence that involves the continued use of cannabis despite problems related to use of the substance.
|
|
Plasminogen activator inhibitor type 1 levels (PAI-1)
|
|
|
Pancreatitis
|
Inflammation of the pancreas.|INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
|
|
Bipolar I disorder
|
A bipolar disorder that is characterized by at least one manic or mixed episode.
|
|
Alzheimer's disease biomarkers
|
|
|
Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy)
|
|
|
Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy)
|
|
|
Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy)
|
|
|
Plasma cystastin c levels in acute coronary syndrome
|
|
|
Electrodermal activity
|
|
|
Response to haloperidol in psychosis
|
|
|
Paget's disease
|
|
|
Urinary metabolites (H-NMR features)
|
|
|
Marginal zone lymphoma
|
|
|
Hashimoto thyroiditis versus Graves' disease
|
|
|
Diabetic nephropathy in type 1 diabetes
|
|
|
Bipolar disorder with mood-incongruent psychosis
|
|
|
Sensory disturbances after bilateral sagittal split ramus osteotomy
|
|
|
Reading or mathematical ability
|
|
|
Colorectal cancer (diet interaction)
|
|
|
Social communication problems
|
|
|
Contrast sensitivity
|
|
|
B-type natriuretic peptide levels
|
|
|
Tooth agenesis (third molar)
|
|
|
Large artery stroke
|
stroke caused by the blockage of blood flow in one of the large arteries feeding the brain
|
|
Coronary artery disease or ischemic stroke
|
|
|
PR interval in Tripanosoma cruzi seropositivity
|
|
|
Ejection fraction in Tripanosoma cruzi seropositivity
|
|
|
Coronary artery disease or large artery stroke
|
|
|
Local histogram emphysema pattern
|
|
|
Aortic stiffness
|
disease cluster belonging to disease group cardiovascular
|
|
Multiple sclerosis or amyotrophic lateral sclerosis
|
|
|
IgG levels
|
|
|
Retinal arteriolar caliber
|
|
|
Blood pressure measurement (cold pressor test)
|
|
|
Blood pressure measurement (low sodium intervention)
|
|
|
Blood pressure measurement (high sodium intervention)
|
|
|
Blood pressure measurement (high sodium and potassium intervention)
|
|
|
Self-reported allergy
|
|
|
Malaria
|
A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.|Malaria is a parasitic disease characterized as a vector-borne arthropod infectious acute or chronic disease caused by the presence of sporozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle. Occurrance is widespread in tropical and subtropical regions, including parts of the Americas, Asia, and Africa.|A protozoan infection caused by the genus Plasmodium. There are four species of Plasmodium that can infect humans: Plasmodium falciparum, vivax, ovale, and malariae. It is transmitted to humans by infected mosquitoes. Signs and symptoms include paroxysmal high fever, sweating, chills, and anemia.|An Aconoidasida infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
|
|
Schizophrenia, schizoaffective disorder or bipolar disorder
|
|
|
Congenital heart disease
|
OMIM mapping confirmed by DO. [SN].
|
|
Endothelial growth factor levels
|
|
|
Congenital left-sided heart lesions (maternal effect)
|
|
|
Response to Dalcetrapib treatment in acute coronary syndrome
|
|
|
Allergic rhinitis in asthma
|
|
|
Red blood cell fatty acid levels
|
|
|
Response to platinum-based agents
|
|
|
Response to antidepressants
|
disease cluster belonging to disease group psych
|
|
Cleft lip
|
|
|
Hepatitis C induced liver fibrosis
|
|
|
Sex hormone-binding globulin levels
|
|
|
Systolic blood pressure in sickle cell anemia
|
|
|
Disc degeneration (lumbar)
|
|
|
Fat body mass
|
The weight of the individual's body fat.
|
|
Follicle stimulating hormone levels
|
|
|
Hormone measurements
|
|
|
Bone properties (heel)
|
|
|
Hereditary hemochromatosis-related traits (HFE mutation homozygotes)
|
|
|
Fasting plasma glucose (childhood)
|
|
|
Esophageal squamous cell carcinoma
|
A squamous cell carcinoma arising from the esophagus. It is associated with a long history of tobacco and alcohol abuse and is exceedingly rare before the age of 30. The median age is around 65 in both males and females. It is located mostly in the middle and lower third of the esophagus. Grossly, polypoid, ulcerated, plaque-like and occult lesions have been described. The microscopic features are the same as in other squamous cell carcinomas. Any degree of differentiation may occur, and variation within a single tumor is common. The prognosis is poor.
|
|
Urinary uromodulin levels
|
|
|
Seasonality
|
|
|
Bronchodilator response in asthma
|
|
|
Response to alcohol consumption (flushing response)
|
|
|
Alcohol consumption (max-drinks)
|
|
|
Response to antidepressant treatment (citalopram)
|
|
|
Cutaneous lupus erythematosus
|
A lupus erythematosus that causes skin lesions on parts of the body that are exposed to sunlight.
|
|
Hand grip strength
|
|
|
Sasang constitutional medicine type (So-Eum)
|
|
|
Information processing speed
|
|
|
Total bilirubin levels in HIV-1 infection
|
|
|
Neutrophil count in HIV-infection
|
|
|
HDL Cholesterol in HIV-infection
|
|
|
Vein graft stenosis in coronary artery bypass grafting
|
|
|
Response to serotonin reuptake inhibitors in major depressive disorder
|
|
|
Cytokine-stimulated IL-6 production
|
|
|
Cytokine and corticosteroid-stimulated IL-6 production
|
|
|
Carotid artery intima media thickness (sex interaction)
|
|
|
Polychlorinated biphenyl levels
|
|
|
Mood disorder and prion disease
|
|
|
Behavioral disturbance or psychiatric symptoms and prion disease
|
|
|
Psychotic symptoms in prion disease
|
|
|
Mood disorder in prion disease
|
|
|
Behavioral disturbance or psychiatric symptoms in prion disease
|
|
|
Developmental dysplasia of the hip
|
|
|
Suicide in bipolar disorder
|
|
|
Yang-deficiency constitution
|
|
|
Diisocyanate-induced asthma
|
|
|
Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio)
|
|
|
Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio)
|
|
|
Pharmacokinetics of olanzapine in severe mental disorder (concentration dose ratio)
|
|
|
Lifespan
|
|
|
Type 1 diabetes and autoimmune thyroid diseases
|
|
|
Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor
|
|
|
AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor
|
|
|
Recalcitrant atopic dermatitis
|
|
|
Prostate cancer aggressiveness
|
|
|
Anxiety disorder
|
A cognitive disorder that involves an excessive, irrational dread of everyday situations.
|
|
Creutzfeldt-Jakob disease (sporadic)
|
|
|
ADAMTS13 activity
|
|
|
Non-small cell lung cancer (survival)
|
|
|
Serum IgE levels
|
disease cluster belonging to disease group immune
|
|
Serum tamsulosin hydrochloride concentration
|
|
|
Ferritin levels
|
|
|
Leishmaniasis (visceral)
|
|
|
Sagittal craniosynostosis
|
A kind of craniosynostosis affecting the sagittal suture.
|
|
Serum total protein levels
|
|
|
Serum albumin levels
|
|
|
Dental caries
|
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. The three most prominent theories used to explain the etiology of the disease are that acids produced by bacteria lead to decalcification; that micro-organisms destroy the enamel protein; or that keratolytic micro-organisms produce chelates that lead to decalcification.
|
|
Cataracts in type 2 diabetes
|
|
|
Chronic obstructive pulmonary disease-related biomarkers
|
|
|
Musician's dystonia
|
|
|
Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative)
|
|
|
Gray matter volume (schizophrenia interaction)
|
|
|
Alcohol and nicotine co-dependence
|
|
|
Food antigen IgG levels
|
|
|
Obesity (early onset extreme)
|
disease cluster belonging to disease group metabolic
|
|
Anterior chamber depth
|
|
|
Lung cancer (SNP x SNP interaction)
|
|
|
Plasma plasminogen levels
|
|
|
Expressive vocabulary in infants
|
|
|
Vogt-Koyanagi-Harada syndrome
|
disease cluster belonging to disease group immune
|
|
Iron status biomarkers (transferrin levels)
|
|
|
Aggressive periodontitis (sex interaction)
|
|
|
Hip circumference (psychosocial stress interaction)
|
|
|
Circulating phylloquinone levels
|
|
|
Diffuse large B cell lymphoma
|
|
|
Response to chemotherapy in breast cancer (hypertension) (bevacizumab)
|
|
|
Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab)
|
|
|
Birdshot chorioretinopathy
|
Birdshot chorioretinopathy is a posterior uveitis characterized by multiple cream-colored, hypopigmented choroidal lesions in the fundus and a strong association with HLA-A29 and clinically presenting with blurred vision, floaters, photopsia, scotoma and nyctalopia.
|
|
Thiazide-induced adverse metabolic effects in hypertensive patients
|
|
|
Proinsulin levels
|
|
|
Acoustic startle blink response
|
|
|
Sickle cell anemia (haemolysis)
|
|
|
Homoarginine levels
|
|
|
Plasma plasminogen activator levels
|
|
|
Iris characteristics
|
|
|
Exfoliation syndrome
|
OMIM mapping confirmed by DO. [SN].
|
|
Lead levels in blood
|
|
|
Hepatitis
|
|
|
Facial pigmentation
|
|
|
Periodontitis
|
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
|
|
Gene methylation in lung tissue
|
|
|
Gastritis
|
A stomach disease that is an inflammation of the lining of the stomach.
|
|
Milk allergy
|
|
|
Egg allergy
|
A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms.
|
|
Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia
|
|
|
Depressive symptoms (SSRI exposure interaction)
|
|
|
Alzheimer's disease (survival time)
|
|
|
Liver enzyme levels (alanine transaminase)
|
|
|
Liver enzyme levels (aspartate transaminase)
|
|
|
Orthostatic hypotension
|
A form of hypotension characterized by a sudden fall in blood pressure that occurs when a person assumes a standing position.
|
|
Eating disorders
|
|
|
Pulmonary function
|
|
|
Insomnia (caffeine-induced)
|
|
|
Fasting blood glucose (BMI interaction)
|
|
|
Fasting blood insulin (BMI interaction)
|
|
|
Fasting blood insulin
|
|
|
Antibody status in Tripanosoma cruzi seropositivity
|
|
|
QRS duration in Tripanosoma cruzi seropositivity
|
|
|
Chagas cardiomyopathy in Tripanosoma cruzi seropositivity
|
|
|
Parasitemia in Tripanosoma cruzi seropositivity
|
|
|
Occipital cortical area (total cortical area interaction)
|
|
|
Osteoporosis
|
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
|
|
Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)
|
|
|
Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid)
|
|
|
Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid)
|
|
|
Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid)
|
|
|
Butyrylcholinesterase levels
|
|
|
Retinol levels
|
|
|
Breast cancer (prognosis)
|
|
|
Temperament
|
|
|
Testosterone levels
|
|
|
Aortic-valve calcification
|
|
|
Coronary arterial lesions in patients with Kawasaki disease
|
|
|
Waist-to-hip circumference ratio (ever vs never smoking interaction)
|
|
|
Body mass index (alcohol intake interaction)
|
|
|
Body mass index (dietary energy interaction)
|
|
|
Body mass index (recreational physical activity interaction)
|
|
|
Body mass index (ever vs never smoking interaction)
|
|
|
Body mass index (smoking years interaction)
|
|
|
Waist-to-hip circumference ratio (dietary energy interaction)
|
|
|
Waist-to-hip circumference ratio (smoking years interaction)
|
|
|
Waist-to-hip circumference ratio (recreational physical activity interaction)
|
|
|
Waist-to-hip circumference ratio (alcohol intake interaction)
|
|
|
Depression and alcohol dependence
|
|
|
Platelet function and related traits
|
|
|
Thyroid volume
|
Is a quantification of the volume of the thyroid.
|
|
Schizophrenia (age at onset)
|
|
|
Temporomandibular joint disorder
|
|
|
Glycemic traits
|
|
|
Vaspin levels
|
|
|
Homeostasis model assessment of beta-cell function (dietary factor interaction)
|
|
|
Homeostasis model assessment of insulin resistance (dietary factor interaction)
|
|
|
Fasting insulin (dietary factor interaction)
|
|
|
Fetal hemoglobin levels
|
|
|
Cardiovascular disease risk factors
|
disease cluster belonging to disease group cardiovascular
|
|
Weight loss (gastric bypass surgery)
|
|
|
Tardive dyskinesia
|
the involuntary movements are tardive, meaning they have a slow or belated onset
|
|
Aging (time to death)
|
|
|
Aging (time to event)
|
|
|
Interstitial lung disease
|
|
|
Wegener's granulomatosis
|
An autoimmune disease that is a vasculitis that is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.
|
|
Digit length ratio
|
Is the ratio of 2D:4D used a a marker for prenatal androgen exposure.
|
|
Meningococcal disease
|
|
|
Hepatocellular carcinoma
|
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.|Tumors or cancer of the LIVER.|A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation. --2002|A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.
|
|
Early cardiac repolarization
|
|
|
Chronic myeloid leukemia
|
A myeloid leukemia that is characterized by over production of white blood cells.
|
|
Testicular cancer
|
A male reproductive system cancer that is located_in the testicles.
|
|
Corneal structure
|
|
|
Epilepsy (remission after treatment)
|
|
|
Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer
|
|
|
Borderline personality disorder features
|
|
|
Migraine with aura
|
A migraine characterized by migraine headache which is preceded or accompanied by a transient focal neurological phenomenon.
|
|
Migraine - clinic-based
|
|
|
Verbal declarative memory
|
|
|
Oligoclonal band status in multiple sclerosis
|
|
|
Immunoglobulin G index levels in multiple sclerosis
|
|
|
Hip circumference
|
|
|
Hippocampal atrophy
|
Atrophy of the hippocampus as a result of some external stress or disease
|
|
Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe mucosal involvement
|
|
|
Gastroesophageal reflux disease, peptic ulcer disease and/or corresponding medications and treatment
|
|
|
Metabolic coherence (transcriptomic)
|
|
|
joint destruction in rheumatoid arthritis (rapid vs slow)
|
|
|
Systolic blood pressure (baseline)
|
|
|
Cognitive function in longevity
|
|
|
Hypertrophic cardiomyopathy (MTAG)
|
|
|
Dilated cardiomyopathy (MTAG)
|
|
|
Left ventricular global radial strain
|
|
|
Left ventricular ejection fraction (MTAG)
|
|
|
Left ventricular mass to end-diastolic volume ratio (MTAG)
|
|
|
Left ventricular mass (MTAG)
|
|
|
Left ventricular end-diastolic volume (MTAG)
|
|
|
Left ventricular end-systolic volume (MTAG)
|
|
|
Left ventricular global circumferential strain (MTAG)
|
|
|
Left ventricular global radial strain (MTAG)
|
|
|
Left ventricular global longitudinal strain (MTAG)
|
|
|
Left ventricle wall thickness
|
|
|
Left ventricular global circumferential strain
|
|
|
Left ventricular mass to end-diastolic volume ratio
|
|
|
Left ventricular global longitudinal strain
|
|
|
Fasting plasma glycodeoxycholate 3-O-glucuronide concentration
|
|
|
Fasting plasma glycochenodeoxycholate 3-O-glucuronide concentration
|
|
|
Psychological resilience (outcome-based) in high deployment stress exposure
|
|
|
Psychological resilience (self-assessed)
|
|
|
Psychological resilience (outcome-based)
|
|
|
Asthma with severe exacerbations
|
|
|
Diverticular disease
|
|
|
Diverticulitis
|
|
|
Cotinine levels in smokers with chronic obstructive pulmonary disease
|
|
|
Smoking cessation in chronic obstructive pulmonary disease
|
|
|
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease
|
|
|
Serum CC16 levels
|
|
|
Urinary albumin excretion (no hypertensive medication)
|
|
|
Helicobacter pylori OMP antibody levels
|
|
|
Anti-herpes simplex virus 2 IgG seropositivity
|
|
|
Anti-polyomavirus 2 IgG seropositivity
|
|
|
Cytomegalovirus pp28 antibody levels
|
|
|
Polyomavirus 2 JC VP1 antibody levels
|
|
|
Anti-Merkel cell polyomavirus IgG seropositivity
|
|
|
Merkel cell polyomavirus VP1 antibody levels
|
|
|
Epstein-Barr virus ZEBRA antibody levels
|
|
|
Anti-human herpesxa0virusxa06xa0IE1A IgGxa0seropositivity
|
|
|
Toxoplasma gondii sag1 antibody levels
|
|
|
Human herpes virusxa06 IE1Axa0antibodyxa0levels
|
|
|
Anti-varicella zoster virus IgG seropositivity
|
|
|
Human herpesxa0virusxa07 U14xa0antibodyxa0levels
|
|
|
BK polyomavirus VP1 antibody levels
|
|
|
Helicobacter pylori UREA antibody levels
|
|
|
Chlamydia trachomatis PorB antibody levels
|
|
|
Herpes simplex virus 2 mgG-1 antibody levels
|
|
|
Anti-Epstein-Barr virus IgG seropositivity
|
|
|
Epstein-Barr virus EA-D antibody levels
|
|
|
Epstein-Barr virus EBNA-1 antibody levels
|
|
|
Epstein-Barr virus VCA p18 antibody levels
|
|
|
Varicella zoster virus glycoproteins E and I antibody levels
|
|
|
Factor VII activity
|
|
|
Factor VII activity or levels
|
|
|
Alzheimer's disease or family history of Alzheimer's disease
|
|
|
Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease
|
|
|
Liver fibrosis in non-alcoholic fatty liver disease
|
|
|
Aspartate aminotransferase levels in non-alcoholic fatty liver disease
|
|
|
Alanine aminotransferase levels in non-alcoholic fatty liver disease
|
|
|
Sweet beverage consumption
|
|
|
Sugar-sweetened beverage consumption
|
|
|
Artificially sweetened beverage consumption
|
|
|
Pure non-grapefruit juice consumption
|
|
|
Bitter beverage consumption
|
|
|
Grapefruit juice consumption
|
|
|
Coronary artery disease and LDL cholesterol levels (multivariate analysis)
|
|
|
Coronary artery disease and triglyceride levels (multivariate analysis)
|
|
|
Acute post-radiotherapy pain in breast cancer
|
|
|
Blood metabolite levels
|
|
|
Academic attainment (English)
|
|
|
BRCA1 mutation in breast cancer
|
|
|
Metabolically unhealthy in obesity
|
|
|
Metabolically unhealthy in normal weight
|
|
|
Addison's disease
|
An adrenal cortical hypofunction that is characterized by insufficient steroid hormone production by the adrenal glands.
|
|
Serum galactose-deficient IgA1 levels in IgA nephropathy
|
|
|
Disruptive behavior disorder and attention deficit hyperactivity disorder
|
|
|
Declining hemoglobin trajectory in blood donors
|
|
|
Frontal fibrosing alopecia
|
|
|
Suicidal ideation
|
A risk factor for suicide attempts and completions, it is the most common of all suicidal behavior, but only a minority of ideators engage in overt self-harm.
|
|
Suicide attempts
|
|
|
Adult asthma
|
|
|
Asthma-chronic obstructive pulmonary disease overlap syndrome
|
|
|
Cirrhosis (alcohol related)
|
|
|
Triiodothyronine levels and thyroxine levels
|
|
|
Glycine levels
|
|
|
Carpal tunnel syndrome
|
OMIM mapping confirmed by DO. [SN].
|
|
Sleep duration (short sleep)
|
|
|
Sleep duration (long sleep)
|
|
|
Early age-related macular degeneration
|
|
|
Digit length ratio (right hand)
|
|
|
Digit length ratio (left hand)
|
|
|
Facial pigmentation measurement (UV light)
|
|
|
Facial pigmentation measurement (polar light)
|
|
|
Cutaneous leishmaniasis
|
A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions.
|
|
Carotid intima media thickness in rheumatoid arthritis
|
|
|
Ischemic heart disease in rheumatoid arthritis
|
|
|
Carotid plaques in rheumatoid arthritis
|
|
|
Triglyceride levels (parental genotype effect)
|
|
|
Triglyceride levels in response to fenofibrate treatment (parental genotype effect)
|
|
|
Chronic back pain
|
|
|
Latent autoimmune diabetes
|
disease cluster belonging to disease group other
|
|
Latent autoimmune diabetes vs. type 2 diabetes
|
|
|
Latent autoimmune diabetes vs. type 1 diabetes
|
|
|
Lateral ventricular volume in normal aging
|
|
|
Hypertension in type 2 diabetes
|
|
|
Colorectal cancer x fine particulate matter exposure levels interaction
|
|
|
Adult body size
|
|
|
Spondylosis
|
An bone structure disease that involves degeneration between vertebra located_in vertebral column.
|
|
D-dimer levels in HIV infection
|
|
|
Interleukin-6 levels in HIV infection
|
|
|
High-sensitivity C-reactive protein levels in HIV infection
|
|
|
Cryptococcosis in HIV infection
|
|
|
Red blood cell folate levels
|
|
|
Hyperglycemia
|
|
|
Hyperglycemia in higher physical activity
|
|
|
Hyperglycemia in more-fat diet
|
|
|
Homeostasis model assessment of insulin resistance in less-fat diet
|
|
|
Hyperinsulinemia x BMI interaction
|
|
|
Hyperinsulinemia x saturated fatty acids interaction
|
|
|
Homeostasis model assessment of insulin resistance x saturated fatty acids interaction
|
|
|
Hyperinsulinemia in obesity
|
|
|
Hyperinsulinemia in lower physical activity
|
|
|
Hyperinsulinemia in less-fat diet
|
|
|
Serum urate levels in chronic kidney disease
|
|
|
Gout in chronic kidney disease
|
|
|
Intra-individual response time variability (selective attention)
|
|
|
Parkinson's disease (age at diagnosis)
|
|
|
Serum 25-Hydroxyvitamin D levels
|
|
|
Nose length
|
|
|
Eye length
|
|
|
Mouth morphology (principal component model)
|
|
|
Nose morphology (partial least square model)
|
|
|
Severe diabetic retinopathy in type 2 diabetes
|
|
|
Blood protein levels
|
|
|
Carotenoid levels
|
|
|
Lipid or lipoprotein levels
|
|
|
Vitamin levels
|
|
|
Chronic periodontitis (localised)
|
|
|
Composite immunoglobulin trait (IgA x IgG)
|
|
|
Composite immunoglobulin trait (IgA/IgG)
|
|
|
Composite immunoglobulin trait (IgA x IgG x IgM)
|
|
|
Composite immunoglobulin trait (IgA/IgM)
|
|
|
Composite immunoglobulin trait (IgA x IgG/IgM)
|
|
|
Composite immunoglobulin trait (IgG/IgM)
|
|
|
IgM levels
|
|
|
Total body bone mineral density
|
|
|
Ulna and radius bone mineral density
|
|
|
Post-bronchodilator FEV1 x air pollution (NO2) interaction in childhood asthma
|
|
|
Asthma (time to childhood onset) in early life tobacco smoke exposure
|
|
|
Asthma (time to childhood onset) x early life tobacco smoke interaction
|
|
|
Adenocarcinoma in never smokers
|
|
|
Pyridoxal 5'-phosphate levels
|
|
|
Plasma pyridoxal phosphate to pyridoxal ratio
|
|
|
Hypospadias (moderate to severe)
|
|
|
Sphingolipid d18:1/d18:2 ratio
|
|
|
Corneal endothelial cell density
|
|
|
Corneal endothelial cell shape (percentage of hexagonally shaped cells)
|
|
|
Intraocular pressure (corneal compensated)
|
|
|
Intraocular pressure (Goldman correlated)
|
|
|
Glucosuria (moderate to severe)
|
|
|
Hematuria (moderate to severe)
|
|
|
Hematuria (mild)
|
|
|
Urine pH measurement
|
|
|
Glucosuria (mild)
|
|
|
Low urine pH
|
|
|
Glucosuria
|
|
|
Proteinuria (moderate to severe)
|
|
|
Proteinuria (mild)
|
|
|
Hematuria
|
The presence of blood in the urine. Hematuria may be gross hematuria (visible to the naked eye) or microscopic hematuria (detected by dipstick or microscopic examination of the urine).
|
|
Ketonuria
|
High levels of ketone bodies in the urine.
|
|
Ketonuria (moderate to severe)
|
|
|
Ketonuria (mild)
|
|
|
Proteinuria
|
|
|
Reduced foot dorsiflexion strength in Charcot-Marie-Tooth disease type 1A
|
|
|
Resistant hypertension
|
|
|
Priapism in sickle cell disease
|
|
|
Neurological blood protein biomarker levels
|
|
|
Upper eyelid sagging severity
|
|
|
Circulating fibroblast growth factor 23 levels
|
|
|
Uterine fibroid number (single vs multiple)
|
|
|
Uterine fibroid size (maximum dimension)
|
|
|
Uterine fibroid size (maximum volume)
|
|
|
Initial alcohol sensitivity
|
|
|
Response to opioid analgesics in cancer (pain decrease)
|
|
|
Nicotine dependence and major depression (severity of comorbidity)
|
|
|
Educational attainment (years of education)
|
|
|
Subiculum volume
|
|
|
Total hippocampal volume
|
|
|
Hippocampal subfield CA3 volume
|
|
|
Hippocampal subfield CA4 volume
|
|
|
Subiculum volume (corrected for total hippocampal volume)
|
|
|
Hippocampal subfield CA1 volume (corrected for total hippocampal volume)
|
|
|
Dentate gyrus granule cell layer volume (corrected for total hippocampal volume)
|
|
|
Dentate gyrus molecular layer volume (corrected for total hippocampal volume)
|
|
|
Hippocampal tail volume (corrected for total hippocampal volume)
|
|
|
Presubiculum volume
|
|
|
Hippocampal subfield CA1 volume
|
|
|
Presubiculum volume (corrected for total hippocampal volume)
|
|
|
Dentate gyrus granule cell layer volume
|
|
|
Dentate gyrus molecular layer volume
|
|
|
Hippocampal fissure volume
|
|
|
Hippocampal tail volume
|
|
|
Nonsyndromic cleft lip with or without cleft palate x sex interaction (2df test)
|
|
|
HATA volume
|
|
|
Inflammatory biomarkers (multivariate analysis)
|
|
|
Body size at age 10
|
|
|
HIgh-sensitivity cardiac troponin T levels (high vs low)
|
|
|
High-sensitivity cardiac troponin T levels
|
|
|
Childhood onset type 2 diabetes
|
|
|
Cognitive impairment test score
|
|
|
Endometrial cancer (endometrioid histology)
|
|
|
Endometrial cancer (Non-endometrioid histology)
|
|
|
Response to TNF inhibitor in rheumatoid arthritis (erythrocyte sedimentation rate)
|
|
|
Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count)
|
|
|
Response to TNF inhibitor in rheumatoid arthritis (change in patient global heath assessment score)
|
|
|
Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count)
|
|
|
Response to TNF inhibitor in rheumatoid arthritis (change in disease activity score)
|
|
|
Waldenstrom macroglobulinemia / lymphoplasmacytic lymphoma
|
|
|
Extremely high intelligence
|
|
|
Radiation-induced brain injury in nasopharyngeal carcinoma
|
|
|
Pulmonary function (FVC) x omega-3 PUFA (docosahexaenoic acid) interaction (2df)
|
|
|
Response to ranibizumab in age-related macular degeneration (exudative)
|
|
|
Diffusing capacity of the lung for carbon monoxide traits
|
|
|
Anti-rubella virus IgG levels
|
|
|
Remission after SSRI treatment in major depression
|
|
|
Relative amplitude of rest-activity cycles
|
|
|
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles)
|
|
|
Barrett's esophagus or esophageal adenocarcinoma x sex interaction (1df test)
|
|
|
Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test)
|
|
|
Barrett's esophagus or Esophageal adenocarcinoma
|
|
|
Childhood asthma with severe exacerbations
|
|
|
Cirrhosis (multi-trait analysis)
|
|
|
Major depressive episode treated with electroconvulsive therapy
|
|
|
Major depressive disorder and major depressive episode treated with electroconvulsive therapy
|
|
|
Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)(time to event)
|
|
|
Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event)
|
|
|
Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)
|
|
|
Response to tofacitinib treatment in psoriasis (herpes zoster)
|
|
|
Response to tofacitinib treatment (herpes zoster)(time to event)
|
|
|
Response to tofacitinib treatment (herpes zoster)
|
|
|
Bipolar disorder (MTAG)
|
|
|
Early chronic obstructive pulmonary disease in never smokers
|
|
|
Major depressive disorder (MTAG)
|
|
|
BRCA1/2-negative high-risk breast cancer
|
|
|
Fasting glucose in pregnancy (gestational week 14-16)
|
|
|
Two-hour glucose in pregnancy (gestational week 30-32)
|
|
|
General glucose level in pregnancy (gestational week 30-32)
|
|
|
Alcohol use disorder (dependence and problematic use scores)
|
|
|
Alcohol use disorder (total score)
|
|
|
Alcohol use disorder (consumption score)
|
|
|
Hip shape (DXA scan)
|
|
|
Seasonality and depression
|
|
|
Hip bone mineral density and total body fat mass (bivariate analysis)
|
|
|
Postburn scar height
|
|
|
Postburn scar pliability
|
|
|
Metabolic syndrome (multivariate analysis)
|
|
|
Offspring birth weight
|
|
|
Cholesteryl ester transfer protein levels
|
|
|
Cerebral microbleeds
|
|
|
Cerebral microbleeds (lobar)
|
|
|
Fish consumption
|
|
|
Hypersomnia (HLA-DQB1*06:02 negative)
|
|
|
Falling risk
|
|
|
Acute lymphoblastic leukemia in childhood (B cell precursor)
|
|
|
Delirium
|
|
|
Change in HbA1c levels in response to metformin treatment in type 2 diabetes
|
|
|
Eye color traits
|
|
|
Skin pigmentation traits
|
|
|
Hair morphology traits
|
|
|
Anthropometric traits (multi-trait analysis)
|
|
|
Anthropometric traits
|
|
|
Disorders of lipid metabolism
|
|
|
Handedness
|
|
|
Response to lurasidone in schizophrenia
|
|
|
Eye movement (horizontal position gain)
|
|
|
Eye movement in schizophrenia (horizontal position gain)
|
|
|
Erectile dysfunction
|
|
|
Myopic maculopathy
|
|
|
Anorexia nervosa or obsessive-compulsive disorder
|
|
|
Serum erythropoietin levels
|
|
|
Waist-to-hip ratio adjusted for BMI (recessive genetic model)
|
|
|
Waist-to-hip ratio adjusted for BMI (additive genetic model)
|
|
|
Recombination rate (males)
|
disease cluster belonging to disease group other
|
|
Recombination rate (females)
|
disease cluster belonging to disease group other
|
|
HIV-1 progression
|
|
|
Suicide risk
|
|
|
Retinal vascular caliber
|
|
|
Factor VII
|
|
|
Hemostatic factors and hematological phenotypes
|
disease cluster belonging to disease group hematological
|
|
IgG glycosylation
|
|
|
Osteonecrosis of the jaw
|
|
|
F-cell distribution
|
disease cluster belonging to disease group hematological
|
|
Oral cavity and pharyngeal cancer
|
|
|
Blond vs. brown hair color
|
|
|
Blue vs. green eyes
|
|
|
Blue vs. brown eyes
|
|
|
Brain structure (hippocampal volume)
|
|
|
Brain structure (temporal lobe volume)
|
|
|
Non-obstructive azoospermia
|
Absence of any measurable level of sperm in his semen, resulting from a defect in the production of spermatozoa in the testes. Can be differentiated from obstructive azoospermia on the basis of testicular biopsy.
|
|
Select biomarker traits
|
disease cluster belonging to disease group other
|
|
Testicular germ cell cancer
|
A testicular cancer that has_material_basis_in germ cells.
|
|
Crohn's disease (time to surgery)
|
|
|
Crohn's disease (need for surgery)
|
|
|
Diabetes (gestational)
|
|
|
Metabolic syndrome (bivariate traits)
|
|
|
Waist Circumference - Triglycerides (WC-TG)
|
|
|
HDL Cholesterol - Triglycerides (HDLC-TG)
|
|
|
Triglycerides-Blood Pressure (TG-BP)
|
|
|
Prostate cancer (SNP x SNP interaction)
|
|
|
Temperament (bipolar disorder)
|
|
|
Other erythrocyte phenotypes
|
disease cluster belonging to disease group hematological
|
|
Dehydroepiandrosterone sulphate levels
|
|
|
Response to tamoxifen in breast cancer
|
|
|
Diabetes (incident)
|
disease cluster belonging to disease group metabolic
|
|
Diabetes related insulin traits
|
disease cluster belonging to disease group metabolic
|
|
Asperger disorder
|
|
|
Glaucoma (exfoliation)
|
disease cluster belonging to disease group vision
|
|
Activated partial thromboplastin time
|
|
|
Rhegmatogenous retinal detachment
|
A type of retinal detachment associated with a retinal tear, that is, with a break in the retina that allows fluid to pass from the vitreous space into the subretinal space between the sensory retina and the retinal pigment epithelium.
|
|
Iron levels
|
disease cluster belonging to disease group metabolic
|
|
Non-alcoholic fatty liver disease histology (lobular)
|
|
|
Non-alcoholic fatty liver disease histology (AST)
|
|
|
Fuchs's corneal dystrophy
|
|
|
Vitamin D insufficiency
|
|
|
Neuranatomic and neurocognitive phenotypes
|
|
|
Alcoholism (12-month weekly alcohol consumption)
|
|
|
Alcoholism (alcohol use disorder factor score)
|
|
|
Alcoholism (alcohol dependence factor score)
|
|
|
Common traits (Other)
|
|
|
Psychosis (methamphetamine induced)
|
|
|
Methamphetamine dependence
|
disease cluster belonging to disease group chemdependency
|
|
Freckling
|
The presence of an increased number of freckles, small circular spots on the skin that are darker than the surrounding skin because of deposits of melanin.
|
|
Biomedical quantitative traits
|
disease cluster belonging to disease group other
|
|
F-cell distribution in sickle cell anaemia
|
|
|
Liver enzyme levels
|
|
|
Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction)
|
|
|
Aging
|
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
|
|
Bipolar disorder and schizophrenia
|
|
|
Serum prostate-specific antigen levels
|
|
|
Quantitative traits
|
disease cluster belonging to disease group other
|
|
Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure)
|
|
|
Neuroblastoma (high-risk)
|
disease cluster belonging to disease group cancer
|
|
Hyperactive-impulsive symptoms
|
disease cluster belonging to disease group psych
|
|
Inattentive symptoms
|
disease cluster belonging to disease group psych
|
|
Optic disc parameters
|
|
|
Age-related macular degeneration (extreme sampling)
|
|
|
Response to hepatitis C treatment
|
disease cluster belonging to disease group pharmacogenomic
|
|
Heart rate variability traits
|
disease cluster belonging to disease group cardiovascular
|
|
Brain structure
|
disease cluster belonging to disease group neurological
|
|
Beta thalassemia/hemoglobin E disease
|
disease cluster belonging to disease group hematological
|
|
Brain imaging
|
|
|
Attention deficit hyperactivity disorder (time to onset)
|
disease cluster belonging to disease group psych
|
|
N-glycan levels
|
|
|
Response to interferon beta therapy
|
|
|
Acenocoumarol maintenance dosage
|
disease cluster belonging to disease group pharmacogenomic
|
|
Hair morphology
|
Any measurable or observable characteristic related to the shape, structure, color, or pattern of the fine, keratinized filamentous growths arising from the epidermis of mammals.
|
|
Folate pathway vitamin levels
|
disease cluster belonging to disease group metabolic
|
|
Subclinical atherosclerosis traits (other)
|
disease cluster belonging to disease group cardiovascular
|
|
Exercise treadmill test traits
|
disease cluster belonging to disease group other
|
|
Echocardiographic traits
|
disease cluster belonging to disease group cardiovascular
|
|
Endothelial function traits
|
disease cluster belonging to disease group cardiovascular
|
|
Hip bone size
|
Is a quantification of the size of a human hip bone.
|
|
Volumetric brain MRI
|
Is a quantification of brain volume using magnetic resonance imaging.
|
|
Cognitive test performance
|
|
|
Primary tooth development (number of teeth)
|
|
|
Primary tooth development (time to first tooth eruption)
|
|
|
Smooth-surface caries
|
|
|
Pit-and-Fissure caries
|
|
|
Lipoprotein-associated phospholipase A2 activity and mass
|
|
|
Optic nerve measurement (cup area)
|
|
|
Optic nerve measurement (rim area)
|
|
|
Optic nerve measurement (disc area)
|
|
|
Optic nerve measurement (cup-to-disc ratio)
|
|
|
Large B-cell lymphoma
|
|
|
Functional MRI
|
|
|
Carotenoid and tocopherol levels
|
|
|
5-HTT brain serotonin transporter levels
|
|
|
Insulin-like growth factors
|
disease cluster belonging to disease group unknown
|
|
Cardiac muscle measurement
|
|
|
Hip geometry
|
Measurements of the hip.
|
|
Cystatin C levels
|
|
|
Tonometry
|
disease cluster belonging to disease group other
|
|
Response to acetaminophen (hepatotoxicity)
|
|
|
Myocardial infarction (early onset)
|
disease cluster belonging to disease group cardiovascular
|
|
Iris color
|
|
|
Lymphoma
|
A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.|A cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.|A general term for various neoplastic diseases of the lymphoid tissue.|Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
|
|
Parkinson's disease (familial)
|
disease cluster belonging to disease group neurological
|
|
YKL-40 levels
|
|
|
Brain lesion load
|
disease cluster belonging to disease group immune
|
|
Multiple sclerosis (severity)
|
disease cluster belonging to disease group immune
|
|
Multiple sclerosis (age of onset)
|
disease cluster belonging to disease group immune
|
|
Normalized brain volume
|
|
|
Aging traits
|
disease cluster belonging to disease group aging
|
|
Morbidity-free survival
|
|
|
Bipolar disorder (age of onset and psychotic symptoms)
|
|
|
Atrial fibrillation/atrial flutter
|
disease cluster belonging to disease group cardiovascular
|
|
Carotid atherosclerosis in HIV infection
|
disease cluster belonging to disease group cardiovascular
|
|
Natriuretic peptide levels
|
|
|
Hearing impairment
|
A decreased magnitude of the sensory perception of sound.
|
|
Creutzfeldt-Jakob disease (variant)
|
|
|
Celiac disease or Rheumatoid arthritis
|
|
|
Cardiac structure and function
|
disease cluster belonging to disease group cardiovascular
|
|
Multiple sclerosis--Brain Glutamate Levels
|
|
|
Beta-trace protein levels
|
|
|
Ankle-brachial index
|
|
|
Electrocardiographic conduction measures
|
disease cluster belonging to disease group cardiovascular
|
|
Cardiovascular risk factors (age interaction)
|
|
|
Cardiovascular risk factors
|
disease cluster belonging to disease group cardiovascular
|
|
Osteosarcoma
|
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)|A malignant mesenchymal tumor arising from the bone.|A usually aggressive malignant bone-forming mesenchymal tumor, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs.
|
|
Serum selenium levels
|
|
|
Soluble E-selectin levels
|
|
|
Pulmonary function (smoking interaction)
|
|
|
Sphingolipid levels
|
|
|
Osteoporosis-related phenotypes
|
disease cluster belonging to disease group metabolic
|
|
Event-related brain oscillations
|
|
|
Suicide attempts in bipolar disorder
|
|
|
Diabetic retinopathy
|
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
|
|
Erectile dysfunction and prostate cancer treatment
|
|
|
Atrioventricular conduction
|
|
|
HIV-1 control
|
disease cluster belonging to disease group infection
|
|
Biochemical measures
|
disease cluster belonging to disease group other
|
|
Soluble levels of adhesion molecules
|
disease cluster belonging to disease group hematological
|
|
Orofacial clefts (maternal alcohol consumption interaction)
|
|
|
Body mass in chronic obstructive pulmonary disease
|
|
|
Mean forced vital capacity from 2 exams
|
disease cluster belonging to disease group cardiovascular
|
|
Congenital heart malformation
|
any structural anomly of the heart that is present from birth
|
|
Alcohol consumption (transferrin glycosylation)
|
|
|
Cutaneous nevi
|
disease cluster belonging to disease group other
|
|
Adiposity
|
disease cluster belonging to disease group metabolic
|
|
Idiopathic dilated cardiomyopathy
|
disease cluster belonging to disease group cardiovascular
|
|
Cardiac hypertrophy
|
an increase in size of the cardiac tissue, not due to increased cell number
|
|
Obesity and osteoporosis
|
disease cluster belonging to disease group metabolic
|
|
Glomerulosclerosis
|
A glomerulonephritis that is characterized by hardening of the glomerulus in the kidney.
|
|
Tanning
|
|
|
C4b binding protein levels
|
|
|
Prion diseases
|
|
|
Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)
|
|
|
Arterial stiffness
|
|
|
Radiation response
|
|
|
Hoarding
|
|
|
Response to metformin in type 2 diabetes (glycemic)
|
|
|
Lp (a) levels
|
|
|
Anti-cyclic Citrullinated Peptide Antibody
|
|
|
Burning and freckling
|
disease cluster belonging to disease group other
|
|
Red vs. non-red hair color
|
|
|
Age-related macular degeneration (wet)
|
disease cluster belonging to disease group vision
|
|
Breast cancer (male)
|
|
|
Amyotrophic lateral sclerosis (age of onset)
|
|
|
Amyotrophic lateral sclerosis (C9orf72 mutation interaction)
|
|
|
Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals
|
|
|
Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals
|
|
|
Head circumference (infant)
|
|
|
Non-albumin protein levels
|
|
|
HPV seropositivity
|
|
|
Neonatal lupus
|
|
|
Vitamin E levels
|
|
|
Chronic kidney disease and serum creatinine levels
|
|
|
Partial epilepsies
|
|
|
Wilms tumor
|
|
|
Esophageal cancer and gastric cancer
|
|
|
Depression (quantitative trait)
|
|
|
Aspirin hydrolysis (plasma)
|
|
|
Breast Cancer in BRCA1 mutation carriers
|
|
|
Anthropometric traits in newborns
|
|
|
Drinking behavior
|
Behaviors associated with the ingesting of water and other liquids; includes rhythmic patterns of drinking (time intervals - onset and duration), frequency and satiety.
|
|
Periodontal microbiota
|
|
|
Response to fenofibrate
|
|
|
Stroke (pediatric)
|
|
|
Sunburns
|
|
|
Circulating myeloperoxidase levels (serum)
|
|
|
Circulating myeloperoxidase levels (plasma)
|
|
|
Dengue shock syndrome
|
A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth.
|
|
Erythrocyte sedimentation rate
|
|
|
Cholelithiasis-related traits in sickle cell anemia
|
|
|
Caffeine consumption
|
|
|
Liver enzyme levels (gamma-glutamyl transferase)
|
|
|
Liver enzyme levels (alkaline phosphatase)
|
|
|
White blood cell types
|
|
|
Estradiol levels
|
|
|
Brain connectivity
|
|
|
Formal thought disorder in schizophrenia
|
|
|
QT interval (drug interaction)
|
|
|
Estradiol plasma levels (breast cancer)
|
|
|
Response to amphetamines
|
|
|
HbA2 levels
|
|
|
Psychosis and Alzheimer's disease
|
|
|
Psychosis in Alzheimer's disease
|
|
|
Lung cancer (asbestos exposure interaction)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)
|
|
|
Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)
|
|
|
Dermatomyositis
|
A myositis and is_a dermatitis that results_in inflammation located_in muscle and located_in skin. The disease may result from either a viral infection or an autoimmune reaction.|A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
|
|
Response to gemcitabine in pancreatic cancer
|
|
|
Cardiovascular heart disease in diabetics
|
|
|
Preeclampsia
|
A pregnancy induced hypertensive state that occurs after 20 weeks of gestation characterized by an increase in blood pressure, along with body swelling and proteinuria.|A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
|
|
Palmitic acid (16:0) levels
|
|
|
Stearic acid (18:0) levels
|
|
|
Type 2 diabetes (dietary heme iron intake interaction)
|
|
|
Sexual dysfunction (SSRI/SNRI-related)
|
|
|
Sexual dysfunction (female)
|
|
|
Age at smoking initiation in chronic obstructive pulmonary disease
|
|
|
Lifetime average cigarettes per day in chronic obstructive pulmonary disease
|
|
|
Esophageal cancer (squamous cell)
|
|
|
Esophageal cancer (alcohol interaction)
|
|
|
Pulmonary function decline
|
|
|
Capecitabine sensitivity
|
|
|
Age-related macular degeneration (choroidal neovascularisation)
|
|
|
Age-related macular degeneration (geographic atrophy)
|
|
|
Age-related macular degeneration (CNV vs. GA)
|
|
|
Hypertension risk in short sleep duration
|
|
|
Response to bleomycin (chromatid breaks)
|
|
|
Bone mineral density (wrist)
|
|
|
Small-cell lung cancer (survival)
|
|
|
Progranulin levels
|
|
|
Epirubicin-induced leukopenia
|
|
|
Adverse response to carbamazepine
|
|
|
Insulin-related traits
|
|
|
Asthma (bronchodilator response)
|
|
|
C-reactive protein and white blood cell count
|
|
|
Response to cholinesterase inhibitors in Alzheimer's disease
|
|
|
Self-employment
|
|
|
Retinopathy in non-diabetics
|
|
|
Thyroid hormone levels
|
|
|
Alzheimer's disease (cognitive decline)
|
|
|
Non-small cell lung cancer
|
|
|
Comprehensive strength and appendicular lean mass
|
|
|
Aspirin exacerbated respiratory disease in asthmatics
|
|
|
Coronary heart disease (SNP X SNP interaction)
|
|
|
Cystic fibrosis severity
|
|
|
Scoliosis
|
An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed)
|
|
Soluble ICAM-1
|
disease cluster belonging to disease group hematological
|
|
Gambling
|
|
|
Lean body mass and age at menarche (combined)
|
|
|
Esophageal squamous cell cancer (length of survival)
|
|
|
Odorant perception (isobutyraldehyde)
|
|
|
Odorant perception (β-ionone)
|
|
|
Response to anti-depressant treatment in major depressive disorder
|
|
|
Molar-incisor hypomineralization
|
a hypomineralisation of systemic origin of one to four permanent first molars frequently associated with affected incisors
|
|
Thyroid cancer (Papillary, radiation-related)
|
|
|
Vascular dementia
|
A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.
|
|
Type 1 diabetes nephropathy
|
Diabetic nephropathy is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. In type 1 diabetes hyperglycaemia starts in the first decades of life and is usually the only recognized cause of nephropathy.
|
|
Serum protein levels (sST2)
|
|
|
Anxiety in major depressive disorder
|
|
|
Anxiety and major depressive disorder
|
|
|
Epstein-Barr virus immune response (EBNA-1)
|
|
|
Multiple sclerosis (OCB status)
|
|
|
Periodontitis (DPAL)
|
|
|
Periodontitis (PAL4Q3)
|
|
|
Periodontitis (Mean PAL)
|
|
|
Periodontitis (CDC/AAP)
|
|
|
Response to tocilizumab in rheumatoid arthritis
|
|
|
B cell non-Hodgkin lymphoma
|
|
|
Lumbar spine bone mineral density
|
|
|
Renal transplant outcome
|
disease cluster belonging to disease group renal
|
|
Thyroid function
|
Physiological activity and functions of the highly vascular thyroid gland, such as producing the thyroid hormones which are concerned in regulating the metabolic rate of the body.
|
|
Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes
|
|
|
Gastric parietal cell autoantibody levels in type 1 diabetes
|
|
|
Thyroid peroxidase autoantibody levels in type 1 diabetes
|
|
|
Intracranial volume
|
|
|
Body mass index and cholesterol (psychopharmacological treatment)
|
|
|
Lipid levels in hepatitis C treatment
|
|
|
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined)
|
|
|
Response to antineoplastic agents
|
|
|
Male fertility
|
|
|
Economic and political preferences
|
|
|
Economic and political preferences (fairness)
|
|
|
Economic and political preferences (feminism/equality)
|
|
|
Economic and political preferences (environmentalism)
|
|
|
Nephropathy
|
|
|
Economic and political preferences (immigration/crime)
|
|
|
Economic and political preferences (time)
|
|
|
Crohn's disease and celiac disease
|
|
|
Response to angiotensin II receptor blocker therapy
|
|
|
Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy)
|
|
|
Blood trace element (Se levels)
|
|
|
Blood trace element (Cu levels)
|
|
|
Blood trace element (Zn levels)
|
|
|
Response to diuretic therapy
|
disease cluster belonging to disease group pharmacogenomic
|
|
Ovarian reserve
|
Ovarian reserve is a term that is used to determine the capacity of the ovary to provide oocytes that are capable of fertilization resulting in a healthy and successful pregnancy. Ovarian reserve is correlated with levels of FSH and anti-Mullerian hormones.
|
|
Hematological parameters
|
disease cluster belonging to disease group hematological
|
|
Cognitive performance
|
|
|
Schizophrenia, bipolar disorder and depression (combined)
|
|
|
Ileal carcinoids
|
|
|
Adverse response to aromatase inhibitors
|
|
|
Pubertal anthropometrics
|
|
|
Protein quantitative trait loci
|
disease cluster belonging to disease group other
|
|
IgE grass sensitization
|
|
|
Response to TNF antagonist treatment
|
disease cluster belonging to disease group pharmacogenomic
|
|
Hypertension (young onset)
|
disease cluster belonging to disease group cardiovascular
|
|
Response to anti-TNF alpha therapy in inflammatory bowel disease
|
|
|
Attention deficit hyperactivity disorder and conduct disorder
|
disease cluster belonging to disease group psych
|
|
Keloid
|
A tough heaped-up scar that rises quite abruptly above the rest of the skin. It is irregularly shaped and tends to enlarge progressively. Keloids arise when there is too much collagen formed in the dermis during the repair of connective tissue.
|
|
Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)
|
|
|
Conduct disorder (maternal expressed emotions interaction)
|
|
|
Black vs. blond hair color
|
|
|
Black vs. red hair color
|
|
|
Biliary atresia
|
A cholestasis characterized by blockage of the ducts that carry bile from the liver to the gallbladder.
|
|
Life threatening arrhythmia
|
|
|
Pulmonary arterial hypertension (without BMPR2 mutations)
|
|
|
β2-Glycoprotein I (β2-GPI) plasma levels
|
|
|
Hematology traits
|
|
|
DNA methylation (parent-of-origin)
|
|
|
DNA methylation (variation)
|
|
|
Relative hand skill in reading disability
|
|
|
Relative hand skill
|
|
|
Response to dabigatran etexilate treatment
|
|
|
Intelligence
|
The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions.
|
|
Prothrombin time
|
|
|
Immune response to anthrax vaccine
|
|
|
Response to Vitamin E supplementation
|
|
|
Ulcerative colitis or Crohn's disease
|
|
|
Electroencephalographic traits in alcoholism
|
|
|
Gamma glutamyl transpeptidase
|
|
|
Response to antipsychotic treatment in schizophrenia (working memory)
|
|
|
Response to antipsychotic treatment in schizophrenia (reasoning)
|
|
|
Renal sinus fat
|
|
|
Airflow obstruction
|
|
|
Tumor biomarkers
|
|
|
Femoral neck bone geometry
|
Femoral neck bone geometry is the quantification of the dimensions of the femoral neck bone of the femur. Femoral neck bone geometry is used in determining risk of hip fracture.
|
|
Clozapine-induced agranulocytosis
|
disease cluster belonging to disease group other
|
|
Urinary symptoms in response to radiotherapy in prostate cancer
|
|
|
Major depressive disorder (broad)
|
disease cluster belonging to disease group psych
|
|
Matrix metalloproteinase levels
|
|
|
Monocyte early outgrowth colony forming units
|
|
|
Platelet aggregation
|
The adhesion of one platelet to one or more other platelets via adhesion molecules.
|
|
Neuroticism (age interaction)
|
|
|
Speech perception in dyslexia
|
disease cluster belonging to disease group psych
|
|
Major mood disorders
|
|
|
Emphysema-related traits
|
|
|
Nephrotic syndrome (acquired)
|
|
|
Myocardial infarction in coronary artery disease
|
|
|
Asthma (toluene diisocyanate-induced)
|
disease cluster belonging to disease group immune
|
|
Brain cytoarchitecture
|
|
|
Response to treatment for acute lymphoblastic leukemia
|
disease cluster belonging to disease group pharmacogenomic
|
|
Creutzfeldt-Jakob disease
|
OMIM mapping confirmed by DO. [SN].
|
|
Two-hour glucose challenge
|
disease cluster belonging to disease group metabolic
|
|
Otosclerosis
|
Formation of spongy bone in the labyrinth capsule which can progress toward the STAPES (stapedial fixation) or anteriorly toward the COCHLEA leading to conductive, sensorineural, or mixed HEARING LOSS. Several genes are associated with familial otosclerosis with varied clinical signs.
|
|
Angiotensin-converting enzyme activity
|
|
|
Lumiracoxib-related liver injury
|
|
|
Moyamoya disease
|
A cerebral arterial disease characterized by constriction of certain arteries at the base of the brain. Blood flow is blocked by the constriction and also by blood clots.
|
|
Bipolar disorder or major depressive disorder
|
|
|
HIV-1 replication
|
|
|
Male infertility
|
|
|
Bitter taste response
|
|
|
Dupuytren's disease
|
disease cluster belonging to disease group other
|
|
Brachial circumference
|
|
|
Helicobacter pylori serologic status
|
|
|
Permanent tooth development
|
|
|
End-stage coagulation
|
|
|
Schizophrenia (negative symptoms)
|
|
|
Aging (facial)
|
|
|
Homeostasis model assessment of beta-cell function
|
|
|
Phytosterol levels
|
|
|
Idiopathic membranous nephropathy
|
|
|
Caudate nucleus volume
|
The volume of the caudate nucleus, a brain structure implicated in many common neurological and psychiatric disorders
|
|
Immunoglobulin A
|
disease cluster belonging to disease group immune
|
|
Ribavirin-induced anemia
|
|
|
Lipoprotein-associated phospholipase A2 activity change in response to statin therapy
|
|
|
Response to citalopram treatment
|
disease cluster belonging to disease group pharmacogenomic
|
|
Metabolic traits
|
disease cluster belonging to disease group metabolic
|
|
Hepatitis C induced liver cirrhosis
|
liver injury resulting from hepatitis C infection
|
|
Waist circumference and related phenotypes
|
disease cluster belonging to disease group metabolic
|
|
Menarche and menopause (age at onset)
|
disease cluster belonging to disease group reproduction
|
|
AIDS
|
A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin&apos;s lymphoma and Kaposi&apos;s sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.|An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.|A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin's lymphoma and Kaposi's sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood. -- 2004|Acquired immunodeficiency syndrome is a HIV infection consisting of a disease of the human immune system that is characterized cytologically especially by a reduction in the numbers of CD4-bearing helper T cells to 20 percent or less of normal thereby rendering the subject highly vulnerable to life-threatening conditions (as Pneumocystis carinii pneumonia) and to some that become life threatening (as Kaposi's sarcoma) and that is caused by infection with HIV commonly transmitted in infected blood especially during illicit intravenous drug use and in bodily secretions (as semen) during sexual intercourse.|An HIV infectious disease that is a characterized cytologically by a reduction in the numbers of CD4-bearing helper T cells to 20 percent or less of normal thereby rendering the subject highly vulnerable to life-threatening conditions (as Pneumocystis carinii pneumonia) and to some that become life threatening (as Kaposi's sarcoma) and that is caused by infection with HIV commonly transmitted in infected blood especially during illicit intravenous drug use and in bodily secretions (as semen) during sexual intercourse.|A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin's lymphoma and Kaposi's sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.|A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per µL of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_agent Human immunodeficiency virus 1 or has_agent Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
|
|
Inflammatory bowel disease (early onset)
|
disease cluster belonging to disease group immune
|
|
Coagulation factor levels
|
|
|
Circulating cell-free DNA
|
|
|
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN)
|
|
|
Renal function-related traits (BUN)
|
|
|
Renal function-related traits (sCR)
|
|
|
Renal function-related traits (eGRFcrea)
|
|
|
Renal function-related traits (urate)
|
|
|
Lentiform nucleus volume
|
|
|
Circulating vasoactive peptide levels
|
|
|
Metabolite levels (HVA/5-HIAA ratio)
|
|
|
Metabolite levels (HVA)
|
|
|
Metabolite levels (5-HIAA)
|
|
|
Metabolite levels (HVA-5-HIAA Factor score)
|
|
|
Body mass index in non-asthmatics
|
|
|
Body mass index in asthmatics
|
|
|
Metabolite levels (5-HIAA/ MHPG Ratio)
|
|
|
Metabolite levels (HVA/MHPG ratio)
|
|
|
Metabolite levels (MHPG)
|
|
|
Response to fenofibrate (adiponectin levels)
|
|
|
Hepatitis B (viral clearance)
|
|
|
Handedness in dyslexia
|
|
|
Coronary restenosis
|
|
|
Dialysis-related mortality
|
|
|
Haptoglobin levels
|
|
|
Sclerosing cholangitis and ulcerative colitis (combined)
|
|
|
Drug-induced liver injury (amoxicillin-clavulanate)
|
|
|
Antipsychotic drug-induced QTc interval prolongation
|
|
|
Fat distribution (HIV)
|
|
|
Addiction
|
strong dependence on an addictive compound such as alcohol or narcotics that results in uncontrollable cravings for such compounds
|
|
Immune reponse to smallpox (secreted IL-12p40)
|
|
|
Immune reponse to smallpox (secreted IL-2)
|
|
|
Immune reponse to smallpox (secreted IL-10)
|
|
|
Immune reponse to smallpox (secreted IL-1beta)
|
|
|
Immune response to smallpox vaccine (IL-6)
|
|
|
Immune reponse to smallpox (secreted TNF-alpha)
|
|
|
Immune reponse to smallpox (secreted IFN-alpha)
|
|
|
Cerivastatin-induced rhabdomyolysis
|
|
|
Response to mTOR inhibitor (everolimus)
|
|
|
Response to mTOR inhibitor (rapamycin)
|
|
|
Femoral neck bone geometry and menarche (age at onset)
|
|
|
Treatment response for severe sepsis
|
|
|
Crohn's disease and psoriasis
|
|
|
Parkinson's disease (motor and cognition)
|
|
|
Duodenal ulcer
|
Adding UMLS CUI for Curling Ulcer C0013295.
|
|
Response to TNF-alpha inhibitors in rheumatoid arthritis
|
|
|
Coronary heart disease event reduction (statin therapy interaction)
|
|
|
HIV-associated dementia
|
|
|
IFN-related cytopenia
|
|
|
Phospholipid levels (plasma)
|
|
|
Adolescent idiopathic scoliosis (severe)
|
|
|
Sexual dimorphism in anthropometric traits
|
|
|
Adverse response to chemotherapy in breast cancer (alopecia)
|
|
|
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU)
|
|
|
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU)
|
|
|
Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel)
|
|
|
Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel)
|
|
|
Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule)
|
|
|
Mortality in heart failure
|
|
|
vWF and FVIII levels
|
|
|
Alopecia areata
|
A hypersensitivity reaction type II disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots.
|
|
End-stage renal disease (non-diabetic)
|
|
|
Thyrotoxic hypokalemic periodic paralysis
|
|
|
Nevirapine-induced rash
|
|
|
Post-traumatic stress disorder (asjusted for relatedness)
|
|
|
Callous-unemotional behaviour
|
bavioural manifestation including low levels of empathy, absence of guilt and emotional unresponsiveness
|
|
Bulimia nervosa
|
An eating disorder that is characterized by a cycle of binge eating (BULIMIA or bingeing) followed by inappropriate acts (purging) to avert weight gain. Purging methods often include self-induced VOMITING, use of LAXATIVES or DIURETICS, excessive exercise, and FASTING.
|
|
Eating disorders (purging via substances)
|
|
|
Schizophrenia (cytomegalovirus infection interaction)
|
|
|
Anticoagulant levels
|
|
|
D-dimer levels
|
|
|
Multiple myeloma (IgH translocation)
|
|
|
Metabolite levels (Dihydroxy docosatrienoic acid)
|
|
|
Metabolite levels (Pyroglutamine)
|
|
|
Metabolite levels (X-11787)
|
|
|
Substance dependence
|
A substance-related disorder that involves the continued use of alcohol or other drugs despite despite problems related to use of the substance.
|
|
Tetralogy of Fallot
|
OMIM mapping confirmed by DO. [LS].
|
|
Erectile dysfunction in type 1 diabetes
|
|
|
Response to iloperidone treatment (QT prolongation)
|
disease cluster belonging to disease group pharmacogenomic
|
|
Adverse response to lamotrigine and phenytoin
|
|
|
Response to irinotecan in non-small-cell lung cancer
|
|
|
Gaucher disease severity
|
|
|
Nephrolithiasis
|
Formation of stones in the KIDNEY.
|
|
Response to metformin (IC50)
|
|
|
Risky sexual behaviors (alcohol dependence interaction)
|
|
|
Risky sexual behaviors in alcohol dependence
|
|
|
Hip minimal joint space width
|
|
|
Carbamazepine-induced maculopapular exanthema
|
|
|
Phenytoin-induced maculopapular exanthema
|
|
|
Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia
|
|
|
Premature menopause in childhood cancer survivors
|
|
|
Stimulated C-peptide levels in type I diabetes
|
|
|
Random C-peptide levels in type I diabetes
|
|
|
C-peptide levels in type I diabetes
|
|
|
Rheumatoid arthritis (ACPA-positive)
|
|
|
Ankle injury
|
|
|
Acute kidney injury in critical illness
|
|
|
Headache
|
Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve.
|
|
Thiopurine methyltransferase activity in acute lymphoblastic leukemia patients treated with mercaptopurines
|
|
|
Worry too long after an embarrassing experience
|
|
|
Feeling fed-up
|
|
|
Feeling nervous
|
|
|
Feeling guilty
|
|
|
Experiencing mood swings
|
|
|
Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer
|
|
|
Sleep latency
|
|
|
Coenzyme Q10 levels
|
|
|
Dysmenorrheic pain
|
|
|
Sulfasalazine-induced agranulocytosis
|
|
|
Early age at menarche
|
|
|
Immunoglobulin measurement (zinc sulfate turbidity test)
|
|
|
Blood sugar levels
|
|
|
Alanine transaminase levels
|
|
|
Forearm bone mineral density
|
|
|
Serum C3d:C3 ratio (systemic complement activation)
|
|
|
Feeling miserable
|
|
|
Neurociticism
|
|
|
Irritable mood
|
|
|
Feeling lonely
|
|
|
Small VLDL particle concentration
|
|
|
Phospholipid levels in small VLDL
|
|
|
Phospholipid levels in large VLDL
|
|
|
Triglyceride levels in large VLDL
|
|
|
Medium VLDL particle concentration
|
|
|
Mean diameter of HDL particles
|
|
|
Triglyceride levels in medium VLDL
|
|
|
Triglyceride levels in small VLDL
|
|
|
Bipolar disorder (early onset)
|
|
|
Response to mepolizumab in severe asthma
|
|
|
Dementia with Lewy bodies
|
|
|
Uveal melanoma
|
A uveal cancer that has_material_basis_in uvea pigment cells.
|
|
Delayed reward discounting
|
|
|
Heart rate response to recovery post exercise
|
|
|
Albumin-globulin ratio
|
|
|
Blood urea nitrogen levels
|
|
|
Creatine kinase levels
|
|
|
Lactate dehydrogenase levels
|
|
|
Cortisol levels (saliva)
|
|
|
CSF tryptophan concentration in tuberculous meningitis
|
|
|
Parkinson's disease (pesticide exposure interaction)
|
|
|
Osteoarthritis of the hip or knee (with total joint replacement)
|
|
|
Survival in head and neck cancer
|
|
|
Pre bronchodilator FEV1/FVC ratio in never-smokers
|
|
|
Alcohol dependence symptom count
|
|
|
Job-related exhaustion in shift workers
|
|
|
Colorectal cancer (alcohol consumption interaction)
|
|
|
Depression in response to interferon-based therapy in chronic hepatitis C
|
|
|
Bipolar disorder lithium response (continuous) or schizophrenia
|
|
|
Bipolar disorder lithium response (categorical) or schizophrenia
|
|
|
Inhibitory control
|
|
|
Heart rate response to exercise
|
|
|
Laterality in neovascular age-related macular degeneration
|
|
|
Hyperuricemia
|
An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood.
|
|
Limited cutaneous systemic scleroderma
|
|
|
Diffuse cutaneous systemic sclerosis
|
|
|
Systemic sclerosis (anti-centromere-positive)
|
|
|
Systemic sclerosis (anti-topoisomerase-positive)
|
|
|
Potassium levels
|
|
|
Chloride levels
|
|
|
Sodium levels
|
|
|
Total bilirubin levels
|
|
|
Hepatitis B virus-related hepatocellular carcinoma
|
|
|
Survival in breast cancer (estrogen-receptor positive)
|
|
|
Thiopurine-induced leukopenia in inflammatory bowel disease
|
|
|
diarrhoeal disease at age 1
|
|
|
diarrhoeal disease at age 1 with doctor diagnosis
|
|
|
diarrhoeal disease at age 2
|
|
|
diarrhoeal disease at age 2 with doctor diagnosis
|
|
|
Feeling worry
|
|
|
Suffering from nerves
|
|
|
Feeling hurt
|
|
|
Feeling tense
|
|
|
Response to antipsychotic treatment in schizophrenia
|
|
|
Response to ziprazidone in schizophrenia
|
|
|
Response to haloperidol in schizophrenia
|
|
|
Response to perphenazine in schizophrenia
|
|
|
Response to aripiprazole in schizophrenia
|
|
|
Response to risperidone in schizophrenia
|
|
|
Response to olanzapine in schizophrenia
|
|
|
Response to quetiapine in schizophrenia
|
|
|
Survival in sporadic amyotrophic lateral sclerosis
|
|
|
Left ventricular QRS voltage
|
|
|
Carotid artery external diameter
|
|
|
Carotid artery internal diameter
|
|
|
Antipsychotic drug-induced QTc interval change in schizophrenia
|
|
|
Nontyphoidal Salmonella bacteraemia
|
|
|
Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232)
|
|
|
Thiopurine-induced severe leukopenia in inflammatory bowel disease
|
|
|
Thiopurine-induced acute severe leukopenia in inflammatory bowel disease
|
|
|
Thiopurine-induced alopecia in inflammatory bowel disease
|
|
|
Thiopurine-induced severe alopecia in inflammatory bowel disease
|
|
|
Thiopurine-induced pancreatitis in inflammatory bowel disease
|
|
|
Thiopurine-induced digestive symptoms in inflammatory bowel disease
|
|
|
Corticosteroid-induced adrenal suppression (peak cortisol < 350 nmol/L)
|
|
|
Corticosteroid-induced adrenal suppression (peak cortisol < 500 nmol/L)
|
|
|
Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma
|
|
|
Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma
|
|
|
Virologic severity in Herpes simplex virus type 2 infection
|
|
|
Serum bilirubin levels in metabolic syndrome
|
|
|
Serum bilirubin levels x sex interaction in metabolic syndrome
|
|
|
Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome
|
|
|
Plantar fascial disorders
|
|
|
Family history of Alzheimer's disease
|
|
|
Esophageal adenocarcinoma x smoking interaction
|
|
|
Esophageal adenocarcinoma x pack-years of smoking exposure interaction
|
|
|
Esophageal adenocarcinoma x gastroesophageal reflux disease interaction
|
|
|
Barrett's esophagus x BMI interaction
|
|
|
Barrett's esophagus x pack-years of smoking exposure interaction
|
|
|
Normal facial asymmetry (angle of surface orientation score)
|
|
|
Normal facial asymmetry (angle of deformation score)
|
|
|
Fast beta electroencephalogram
|
|
|
Normal facial asymmetry (deformation magnitude)
|
|
|
Cisplatin-induced ototoxicity
|
|
|
Poor prognosis in Crohn's disease
|
|
|
Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL)
|
|
|
Liver disease severity in Alagille syndrome
|
|
|
Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities)
|
|
|
Moderate to vigorous physical activity levels
|
|
|
Vigorous physical activity
|
|
|
Strenuous sports or other exercises
|
|
|
Accelerometer-based physical activity measurement (average acceleration)
|
|
|
Factor XI
|
|
|
Erosive tooth wear (severe vs non-severe)
|
|
|
Erosive tooth wear (severe vs none or mild)
|
|
|
Hyperthyroidism
|
A thyroid gland disease that involves an over production of thyroid hormone.
|
|
Free cholesterol levels in medium HDL
|
|
|
Phospholipid levels in large HDL
|
|
|
Total cholesterol levels in large HDL
|
|
|
Cholesterol ester levels in very large HDL
|
|
|
Free cholesterol levels in large HDL
|
|
|
Medium HDL particle concentration
|
|
|
Phospholipid levels in medium HDL
|
|
|
Free cholesterol levels in large LDL
|
|
|
Medium LDL particle concentration
|
|
|
Total cholesterol levels in medium LDL
|
|
|
Cholesterol ester levels in medium LDL
|
|
|
Mortality in sepsis
|
|
|
Thiopurine S-methyltransferase activity
|
Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
|
|
Drug abuse
|
|
|
Ratio of the area under the curve for insulin and the area under the curve for glucose
|
|
|
Area under the curve of insulin levels
|
|
|
Incremental insulin
|
|
|
Corrected insulin response
|
|
|
Corrected insulin response adjusted for insulin sensitivity index
|
|
|
Hair shape
|
|
|
Overall survival in osteosarcoma
|
|
|
Food addiction
|
|
|
Male sexual orientation
|
|
|
Epstein Barr virus nuclear antigen 1 IgG seropositivity
|
|
|
Viral capsid antigen IgG seropositivity
|
|
|
Epstein-Barr virus immune response (multivariate analysis)
|
|
|
Giant cell arteritis
|
|
|
ADAMTS13 levels
|
|
|
Ejection fraction
|
|
|
Left ventricular internal dimension in diastole
|
|
|
Left ventricular internal dimension in systole
|
|
|
Fractional shortening
|
|
|
Attention deficit hyperactivity disorder or cannabis use
|
|
|
Autoimmune hepatitis in primary sclerosing cholangitis
|
|
|
Liver transplant-free survival in primary sclerosing cholangitis (time to event)
|
|
|
Cholangiocarcinoma in primary sclerosing cholangitis
|
|
|
Cholangiocarcinoma in primary sclerosing cholangitis (time to event)
|
|
|
Colorectal carcinoma in primary sclerosing cholangitis
|
|
|
Fractures (vertebral)
|
|
|
Putamen volume
|
|
|
Mortality
|
Is the quantification of the number of deaths is a population.
|
|
Systemic lupus erythematosus or rheumatoid arthritis
|
|
|
Severe progression in rheumatoid arthritis
|
|
|
Breast milk fatty acid composition (maternal genotype effect)
|
|
|
Breast milk fatty acid composition (infant genotype effect)
|
|
|
Joint damage in rheumatoid arthritis
|
|
|
Empathy quotient
|
|
|
Urinary haptoglobin levels in type 2 diabetes
|
|
|
Plasma haptoglobin levels in type 2 diabetes
|
|
|
Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction)
|
|
|
Cleft lip with or without cleft palate (maternal periconceptional alcohol intake interaction)
|
|
|
Broad depression or major depressive disorder (self-reported)
|
|
|
Broad depression or major depressive disorder (recurrent)
|
|
|
Broad depression or bipolar disorder
|
|
|
Broad depression or schizophrenia
|
|
|
Change in glucose in response to thiazide diuretic treatment in hypertension
|
|
|
Smoking behaviour (maximum cigarettes in a 24 hour period)
|
|
|
Serum metabolite concentrations in chronic kidney disease
|
|
|
Urinary metabolite ratios in chronic kidney disease
|
|
|
Serum metabolite ratios in chronic kidney disease
|
|
|
Nicotine withdrawal symptom count
|
|
|
Nicotine withdrawal
|
|
|
Large HDL particle concentration
|
|
|
Free cholesterol levels in medium VLDL
|
|
|
Total cholesterol levels in large LDL
|
|
|
Cholesterol ester levels in large LDL
|
|
|
Total cholesterol levels in medium VLDL
|
|
|
Large LDL particle concentration
|
|
|
Small LDL particle concentration
|
|
|
Total cholesterol levels in small LDL
|
|
|
Selective IgA deficiency
|
|
|
Insulin sensitivity index
|
|
|
Insulin levels
|
|
|
Mosaic loss of chromosome Y
|
|
|
Insulin levels adjusted for BMI
|
|
|
Pediatric areal bone mineral density (concordant skeletal phenotype)
|
|
|
Pediatric areal bone mineral density (radius vs spine & hip discordant skeletal phenotype)
|
|
|
Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype)
|
|
|
Pseudoexfoliation syndrome
|
|
|
Dimensional psychopathology (Arousal)
|
|
|
Dimensional psychopathology (Negative)
|
|
|
Dimensional psychopathology (Social)
|
|
|
Dimensional psychopathology (Positive)
|
|
|
Dimensional psychopathology (Cognitive)
|
|
|
Major depressive disorder (unexposed to adversity)
|
|
|
Age at first sexual intercourse
|
|
|
Bone mineral density x blood lead interaction in current smokers (2df test)
|
|
|
Bone mineral density x blood lead interaction in current smokers (1df test)
|
|
|
Immunoglobulin M against phosphorylcholine (IgM anti-PC) levels
|
|
|
Fractional excretion of metabolites in chronic kidney disease
|
|
|
Mood instability
|
|
|
Alzheimer's disease in hypertension-negative individuals
|
|
|
Alzheimer's disease in hypertension
|
|
|
Bicuspid aortic valve without aortic dilation
|
|
|
Subscapular skin fold thickness
|
|
|
Dentate gyrus volume x schizophrenia interaction
|
|
|
Pneumococcal meningitis x streptococcus pneumoniae genotype cluster interaction
|
|
|
Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction
|
|
|
Pneumococcal meningitis
|
|
|
Severe bacterial meningitis
|
|
|
Alzheimer’s disease and/or vascular dementia (clinical subgroup VaD+)
|
|
|
Alzheimer’s disease (clinical subgroup AD+)
|
|
|
Alzheimer’s disease (clinical subgroup AD++)
|
|
|
Alzheimer’s disease (clinical subgroup AD+++)
|
|
|
Alzheimer’s disease and/or vascular dementia (clinical subgroup VaD++)
|
|
|
Adverse response to drug
|
|
|
Ceramide levels
|
|
|
Lysophosphatidylcholine levels
|
|
|
Lysophosphatidylethanolamine levels
|
|
|
Triacylglyceride levels
|
|
|
Phosphatidylethanolamine-ether levels
|
|
|
Phosphatidylinositol levels
|
|
|
Cholesteryl ester levels
|
|
|
Sphingomyelin levels
|
|
|
Phosphatidylcholine levels
|
|
|
Phosphatidylcholine-ether levels
|
|
|
Phosphatidylethanolamine levels
|
|
|
Smoking behaviour (age at first cigarette)
|
|
|
Smoking behaviour (cigarette pack-years)
|
|
|
Nonsyndromic cleft lip
|
|
|
Nonsyndromic cleft palate
|
|
|
Depressive symptom (depressed mood) (binary trait)
|
|
|
Depressive symptom (sleep problems) (binary trait)
|
|
|
Depressive symptom (appetite changes) (binary trait)
|
|
|
Depressive symptoms (binary sum-score)
|
|
|
Depressive symptoms (sum-score)
|
|
|
Depressive symptom (fatigue) (ordinal trait)
|
|
|
Depressive symptom (low self-esteem) (ordinal trait)
|
|
|
Depressive symptom (anhedonia) (ordinal trait)
|
|
|
Depressive symptom (depressed mood) (ordinal trait)
|
|
|
Colorectal cancer or advanced adenoma
|
|
|
Intake of sweets
|
|
|
Perceived sweetness of sucrose
|
|
|
Sucrose liking
|
|
|
Perceived intensity of fructose
|
|
|
Perceived intensity of neohesperidin dihydrochalcone
|
|
|
Perceived intensity of aspartame
|
|
|
Perceived intensity of sweet substances
|
|
|
Perceived intensity of sucrose
|
|
|
Intake of total sugars
|
|
|
Perceived intensity of glucose
|
|
|
Psychotic experience
|
|
|
Psychotic experience (distressing)
|
|
|
Estimated glomerular filtration rate in diabetes
|
|
|
Estimated glomerular filtration rate in non-diabetics
|
|
|
Childhood steroid-sensitive nephrotic syndrome
|
|
|
Handedness (non-right-handed vs right-handed)
|
|
|
Handedness (Left-handed vs. non-left-handed)
|
|
|
Handedness (left-handed vs. right-handed)
|
|
|
Forehead morphology
|
|
|
Lip morphology
|
|
|
Upper eyelid morphology
|
|
|
Differential aging in older adults (frontal cortex)
|
|
|
Differential aging (frontal cortex)
|
|
|
Subjective response to placebo treatment in childhood asthma (change in cough/wheeze)
|
|
|
Response to placebo treatment in childhood asthma (FVC change)
|
|
|
Caudal anterior-cingulate cortex volume
|
|
|
Cuneus cortex volume
|
|
|
Caudal middle frontal gyrus volume
|
|
|
Fusiform gyrus volume
|
|
|
Inferior parietal cortex volume
|
|
|
Inferior temporal gyrus volume
|
|
|
Pericalcarine cortex volume
|
|
|
Postcentral gyrus volume
|
|
|
Posterior-cingulate cortex volume
|
|
|
Lateral occipital cortex volume
|
|
|
Lateral orbital frontal cortex volume
|
|
|
Lingual gyrus volume
|
|
|
Paracentral lobule volume
|
|
|
Pars opercularis volume
|
|
|
Pars orbitalis volume
|
|
|
Pars triangularis volume
|
|
|
Middle temporal gyrus volume
|
|
|
Parahippocampal gyrus volume
|
|
|
Isthmus-cingulate cortex volume
|
|
|
Medial orbital frontal cortex volume
|
|
|
Rostral anterior cingulate cortex volume
|
|
|
Rostral middle frontal gyrus volume
|
|
|
Superior frontal gyrus volume
|
|
|
Superior parietal cortex volume
|
|
|
Superior temporal gyrus volume
|
|
|
Supramarginal gyrus volume
|
|
|
Precuneus cortex volume
|
|
|
Temporal pole volume
|
|
|
Transverse temporal cortex volume
|
|
|
Insular cortex volume
|
|
|
Frontal pole volume
|
|
|
Corpus callosum central volume
|
|
|
Corpus callosum mid-anterior volume
|
|
|
Corpus callosum anterior volume
|
|
|
Cortex volume
|
|
|
Fourth ventricle volume
|
|
|
Corpus callosum posterior volume
|
|
|
Corpus callosum Mid-posterior volume
|
|
|
Lateral ventricle temporal horn volume
|
|
|
Lateral ventricle volume
|
|
|
Third ventricle volume
|
|
|
Ventral diencephalon volume
|
|
|
Choroid plexus volume
|
|
|
Pallidum volume
|
|
|
Amygdala volume
|
|
|
Thalamus volume
|
|
|
Cerebellum cortex volume
|
|
|
Superior temporal sulcus banks volume
|
|
|
Total intracranial volume
|
|
|
Cerebellum white matter volume
|
|
|
Cerebral white matter volume
|
|
|
Whole brain grey matter density
|
|
|
Sub-cortical grey matter volume
|
|
|
Total grey matter volume
|
|
|
Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)
|
|
|
Systolic blood pressure x alcohol consumption interaction (2df test)
|
|
|
Familial lung adenocarcinoma
|
|
|
Familial squamous cell lung carcinoma
|
|
|
Familial lung cancer
|
|
|
Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)
|
|
|
Pulse pressure x alcohol consumption interaction (2df test)
|
|
|
BMI (adjusted for smoking behaviour)
|
|
|
Itch intensity from mosquito bite adjusted by bite size
|
|
|
Body mass index (adult)
|
|
|
Tacrolimus trough concentration in kidney transplant patients
|
|
|
Psychosis proneness (hypomanic personality scale)
|
|
|
Psychosis proneness (perceptual aberration scale)
|
|
|
Psychosis proneness (revised physical anhedonia scale)
|
|
|
Psychosis proneness (revised social anhedonia scale)
|
|
|
Psychosis proneness (hypomanic personality scale and perceptual aberration scale)
|
|
|
Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale)
|
|
|
Psychosis proneness (hypomanic personality scale and revised social anhedonia scale)
|
|
|
Psychosis proneness (perceptual aberration scale and revised physical anhedonia scale)
|
|
|
Psychosis proneness (perceptual aberration scale and revised social anhedonia scale)
|
|
|
Psychosis proneness (revised physical anhedonia scale and revised social anhedonia scale)
|
|
|
vWF levels in ischaemic stroke and hyperhomocysteinaemia
|
|
|
Parental longevity (at least one long-lived parent)
|
|
|
Tenofovir clearance in HIV infection
|
|
|
Itch intensity from mosquito bite
|
|
|
Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)
|
|
|
Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction)
|
|
|
Preterm birth (maternal effect)
|
|
|
Skin aging (microtopography measurement)
|
|
|
Restricted and repetitive behaviours in autism spectrum disorder
|
|
|
Chronic periodontitis (mean interproximal clinical attachment level)
|
|
|
Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction)
|
|
|
Conotruncal heart defects (maternal effects)
|
|
|
Conotruncal heart defects (inherited effects)
|
|
|
Left ventricular obstructive tract defect (inherited effect)
|
|
|
Left ventricular obstructive tract defect (maternal effect)
|
|
|
Congenital heart disease (inherited effect)
|
|
|
Congenital heart disease (maternal effect)
|
|
|
Early onset atrial fibrillation
|
|
|
Mean arterial pressure x alcohol consumption interaction (2df test)
|
|
|
Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test)
|
|
|
Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test)
|
|
|
Resting-state electroencephalogram vigilance
|
|
|
Intertrochanteric region size
|
|
|
Trochanter size
|
|
|
Fasting blood insulin adjusted for BMI
|
|
|
Fasting blood glucose adjusted for BMI
|
|
|
Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis
|
|
|
Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis
|
|
|
Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis
|
|
|
Soluble VCAM-1 levels
|
|
|
Endometriosis or endometrial cancer (pleiotropy)
|
|
|
Diffusing capacity of carbon monoxide
|
|
|
Placental abruption
|
A placenta disease that is characterized by separation of the placental lining from the uterus of the mother.
|
|
Non-steroidal anti-inflammatory drug-induced enteropathy
|
|
|
Lymphangioleiomyomatosis (sporadic)
|
|
|
Medication use (agents acting on the renin-angiotensin system)
|
|
|
Medication use (calcium channel blockers)
|
|
|
Medication use (beta blocking agents)
|
|
|
Medication use (antiglaucoma preparations and miotics)
|
|
|
KANNO antigen negativity
|
|
|
Urinary potassium to creatinine ratio
|
|
|
Urinary sodium to creatinine ratio
|
|
|
Urinary sodium to potassium ratio
|
|
|
Monoclonal gammopathy of undetermined significance
|
|
|
Growth differentiation factor-15 levels (conditioned on rs888663)
|
|
|
Growth differentiation factor-15 levels
|
|
|
Thyrotoxic hypokalemic periodic paralysis and Graves disease
|
|
|
Cardiac troponin-I levels
|
|
|
Ventricular ectopy or supraventricular ectopy (pleiotropy)
|
|
|
Ventricular ectopy
|
|
|
Supraventricular ectopy
|
|
|
Idiopathic intracranial hypertension
|
|
|
Aortic coarctation
|
|
|
Clostridium difficile infection in multiple myeloma
|
|
|
Low white blood cell count
|
|
|
Low white blood cell count (conditioned on rs2814778)
|
|
|
Asthma exacerbations in inhaled corticosteroid treatment
|
|
|
Benign prostatic hyperplasia
|
A non-cancerous nodular enlargement of the prostate gland. It is characterized by the presence of epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. It is the most common urologic disorder in men, causing blockage of urine flow.|A disease caused by hyperplastic process of non-transformed prostatic cells.|Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
|
|
Self-reported childhood asthma in adult smokers
|
|
|
Post-traumatic stress disorder symptoms in trauma-exposed soldiers
|
|
|
Medication use (thyroid preparations)
|
|
|
Medication use (immunosuppressants)
|
|
|
Medication use (anti-inflammatory and antirheumatic products, non-steroids)
|
|
|
Medication use (drugs affecting bone structure and mineralization)
|
|
|
Medication use (opioids)
|
|
|
Medication use (salicylic acid and derivatives)
|
|
|
Medication use (anilides)
|
|
|
Medication use (antimigraine preparations)
|
|
|
Medication use (antidepressants)
|
|
|
Medication use (adrenergics, inhalants)
|
|
|
Medication use (glucocorticoids)
|
|
|
Medication use (antihistamines for systemic use)
|
|
|
Infliximab-induced mucosal healing in Crohn's disease
|
|
|
Femoral neck size
|
|
|
Renal cell carcinoma x sex interaction
|
|
|
Response to SSRI in MDD or conscientiousness
|
|
|
Remission after SSRI treatment in MDD or neuroticism
|
|
|
Remission after SSRI treatment in MDD or openness
|
|
|
Response to SSRI in MDD or openness
|
|
|
Global electrical heterogeneity phenotypes
|
|
|
Lipid traits (pleiotropy) (HIPO component 2)
|
|
|
Social science traits (pleiotropy) (HIPO component 1)
|
|
|
Lipid traits (pleiotropy) (HIPO component 1)
|
|
|
Antidepressant treatment resistance (> 2 drugs prescribed)
|
|
|
Antidepressant treatment resistance (number of drugs prescribed)
|
|
|
Neuropathic pain in head and neck cancer
|
|
|
Cortical amyloid beta load
|
|
|
Alzheimer's disease progression score
|
|
|
Cholesterol efflux capacity
|
|
|
Cholesterol efflux capacity (cAMP stimulated assay)
|
|
|
Body mass index and waist-hip ratio (pleiotropy)
|
|
|
Sural nerve amplitude potential
|
|
|
Glycemic traits (pleiotropy)
|
|
|
Bisphosphonate-associated atypical femoral fracture
|
|
|
Atypical femoral fracture in phosphonate treatment
|
|
|
Medication use (drugs used in diabetes)
|
|
|
Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease)
|
|
|
Medication use (antithrombotic agents)
|
|
|
Medication use (vasodilators used in cardiac diseases)
|
|
|
Medication use (antihypertensives)
|
|
|
Medication use (diuretics)
|
|
|
Medication use (HMG CoA reductase inhibitors)
|
|
|
Severity of nausea and vomiting of pregnancy
|
|
|
Hyperemesis gravidarum
|
Excessive vomiting in early pregnancy, leading to the loss of 5% or more of body weight.
|
|
Anti-adalimumab antibody production in response to treatment in Crohn's disease
|
|
|
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)
|
|
|
Age-related macular degeneration (MTAG)
|
|
|
Sero-negative rheumatoid arthritis
|
|
|
Sub-foveal choroidal thickness
|
|
|
Obesity (extreme) (SNP x SNP interaction)
|
|
|
Carotid plaque
|
disease cluster belonging to disease group cardiovascular
|
|
Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP
|
|
|
Health literacy
|
|
|
Autoimmune traits (pleiotropy)
|
|
|
Pre-treatment viral load in HIV-1 infection
|
|
|
Asthma (age of onset)
|
|
|
Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals
|
|
|
Anxiety and stress-related disorders
|
|
|
Stress-related disorders
|
|
|
Anxiety and stress-related disorders (excluding adjustment disorder)
|
|
|
Anxiety and stress-related disorders (excluding co-morbid schizophrenia)
|
|
|
Anxiety and stress-related disorders (including obsessive-compulsive disorder)
|
|
|
Anxiety and stress-related disorders (psychiatric co-morbidity weighting design)
|
|
|
Anxiety and stress-related disorders (psychiatric co-morbidity covariate model)
|
|
|
Low susceptibility to hepatitis C infection
|
|
|
Adult hearing difficulty
|
|
|
Adult hearing aid use
|
|
|
Breast cancer and/or colorectal cancer
|
|
|
BMI at birth
|
|
|
BMI at 3 months old
|
|
|
BMI at 6 months old
|
|
|
BMI at 8 months old
|
|
|
BMI at 1 year old
|
|
|
BMI at 1.5 years old
|
|
|
BMI at 2 years old
|
|
|
BMI at 3 years old
|
|
|
BMI at 5 years old
|
|
|
BMI at 7 years old
|
|
|
BMI at 8 years old
|
|
|
Percent glycated albumin
|
|
|
Total glycated albumin levels
|
|
|
Fructosamine levels
|
|
|
Emotional lability in attention deficit hyperactivity disorder
|
|
|
Right-sided colonic diverticulosis
|
|
|
Primary central nervous system lymphoma
|
|
|
Alcohol dependence (tolerance)
|
|
|
Alcohol dependence (desire to cut drinking)
|
|
|
Alcohol dependence (time spent drinking)
|
|
|
Cellular nuclear factor (erythroid-derived 2)-like 2 levels
|
|
|
Bicuspid aortic valve
|
The presence of an aortic valve with two instead of the normal three cusps (flaps).
|
|
Pemphigus vulgaris
|
An autoimmune blistering disorder. It is characterized by the presence of painful blisters and erosions in the skin and mucous membranes.
|
|
Number of twin births
|
|
|
Plasma anastrozole concentration in anastrozole-treated estrogen receptor positive breast cancer
|
|
|
Handedness (Right-handed vs. non-right-handed)
|
|
|
Response to intravenous immunoglobulin treatment in Kawasaki disease
|
|
|
Urolithiasis
|
presence of calculi in any part of the urinary system
|
|
Sleep (number of episodes)
|
|
|
Plasma norclozapine levels in treatment-resistant schizophrenia
|
|
|
Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia
|
|
|
Plasma clozapine levels in treatment-resistant schizophrenia
|
|
|
Arterial stiffness index
|
|
|
Acute lymphoblastic leukemia
|
When the disease process is confined to a mass lesion with no or minimal evidence of blood and less than 25% marrow involvement, the diagnosis is lymphoblastic lymphoma; with blood and greater than 25% marrow involvement, ALL is the appropriate term.|Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the acute B lymphoblastic leukemia and acute T lymphoblastic leukemia.|A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.|A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.|Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the precursor B lymphoblastic leukemia and precursor T lymphoblastic leukemia.
|
|
Acute lymphoblastic leukemia (adult)
|
|
|
Acute lymphoblastic leukemia (adult vs childhood)
|
|
|
Early-onset schizophrenia
|
|
|
Response to resistance training (vastus lateralis fiber area change)
|
|
|
Complement C3 levels
|
|
|
Complement C4 levels
|
|
|
Orofacial cleft x maternal periconceptional smoking interaction (1df)
|
|
|
Orofacial cleft x maternal periconceptional alcohol use interaction (1df)
|
|
|
Orofacial cleft x maternal periconceptional multivitamin use interaction (1df)
|
|
|
Orofacial cleft x maternal periconceptional smoking interaction (2df)
|
|
|
Orofacial cleft x maternal periconceptional alcohol use interaction (2df)
|
|
|
Orofacial cleft x maternal periconceptional multivitamin use interaction (2df)
|
|
|
Computer vision syndrome
|
|
|
Gout vs asymptomatic hyperuricemia
|
|
|
Severe exacerbations in childhood asthma
|
|
|
Appendicular lean mass
|
|
|
Excessive alcohol consumption
|
|
|
Nevus count
|
|
|
Facial wrinkles (principal components analysis)
|
|
|
COVID-19
|
|
|
Cannabis use disorder
|
|
|
Hip index
|
|
|
Waist-hip index
|
|
|
Cataracts
|
|
|
ABO blood group (O vs non-O)
|
|
|
ABO blood group (A vs O)
|
|
|
ABO blood group (B vs O)
|
|
|
ABO blood group (AB vs O)
|
|
|
ABO blood group (A vs non-A)
|
|
|
ABO blood group (B vs non-B)
|
|
|
ABO blood group (AB vs non-AB)
|
|
|
Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty)
|
|
|
Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio)
|
|
|
Acute respiratory distress syndrome
|
disease cluster belonging to disease group unknown
|
|
Lung cancer prognosis in former smokers
|
|
|
Asthma and eczema
|
|
|
Hand osteoarthritis severity (hand Klsum)
|
|
|
Finger osteoarthritis severity (hand Klsum)
|
|
|
Thumb osteoarthritis severity (hand Klsum)
|
|
|
A body shape index
|
|
|
Relative brain age
|
|
|
Complement factor H levels
|
|
|
Complement factor H-related protein 1 levels
|
|
|
Complement factor H-related protein 2 levels
|
|
|
Complement factor H-related protein 3 levels
|
|
|
Complement factor H-related protein 4A levels
|
|
|
Complement factor H-related protein 5 levels
|
|
|
Polycystic ovary syndrome (adjusted for age)
|
|
|
Polycystic ovary syndrome (adjusted for age and BMI)
|
|
|
DHEAS levels
|
|
|
BMI in non-smokers
|
|
|
Perceived unattractiveness to mosquitoes
|
|
|
Mosquito bite size
|
|
|
Seborrheic dermatitis
|
A dermatitis that is an inflammatory skin condition resulting in flaky, white to yellowish scales on oily areas such as the scalp or inside the ear, which is caused due to a combination of an over production of skin oil and irritation from a yeast Malassezia furfur. The symptoms include itching, skin lesions and scales, redness, plaques and hair loss.
|
|
Energy expenditure (24h)
|
|
|
Resting metabolic rate
|
|
|
Left ventricular function change in anthracycline treatment
|
|
|
Body mass index (joint analysis main effects and physical activity interaction)
|
|
|
Residual cognition
|
|
|
Body mass index (joint analysis main effects and smoking interaction)
|
|
|
Waist circumference adjusted for BMI in non-smokers
|
|
|
Body mass index (physical activity interaction)
|
|
|
BMI in smokers
|
|
|
Waist-to-hip ratio adjusted for BMI in non-smokers
|
|
|
Waist circumference adjusted for BMI in smokers
|
|
|
Blood pressure traits (multi-trait analysis)
|
|
|
Interleukin-6 (red blood cell fatty acid level interaction)
|
|
|
Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction)
|
|
|
Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction)
|
|
|
Tumor necrosis factor receptor II (red blood cell fatty acid level interaction)
|
|
|
C-reactive protein (red blood cell fatty acid level interaction)
|
|
|
Elevated serum prostate-specific antigen levels in healthy men
|
|
|
Waist-to-hip ratio adjusted for BMI in smokers
|
|
|
Prevalent type 2 diabetes
|
|
|
White blood cell count (eosinophil)
|
|
|
White blood cell count (lymphocyte)
|
|
|
White blood cell count (monocyte)
|
|
|
Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis
|
|
|
White blood cell count (neutrophil)
|
|
|
Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour)
|
|
|
Waist-to-hip ratio adjusted for BMI (smoking interaction)
|
|
|
Waist circumference adjusted for BMI (smoking interaction)
|
|
|
Peak insulin response
|
|
|
Acute insulin response
|
|
|
Insulin secretion rate
|
|
|
Peak insulin response (BMI and insulin secretion adjusted)
|
|
|
Peak insulin response (insulin secretion adjusted)
|
|
|
Acute insulin response (insulin secretion adjusted)
|
|
|
Bone ultrasound measurement (velocity of sound)
|
|
|
Bone ultrasound measurement (broadband ultrasound attenuation)
|
|
|
Bone erosion in rheumatoid arthritis
|
|
|
Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)
|
|
|
Body mass index in physically active individuals
|
|
|
Body mass index in physically inactive individuals
|
|
|
Waist circumference adjusted for BMI in active individuals
|
|
|
Survival in pancreatic cancer
|
|
|
Waist circumference adjusted for BMI (adjusted for smoking behaviour)
|
|
|
BMI (smoking interaction)
|
|
|
Time-dependent creatinine clearance change response to tenofovir treatment in HIV infection (time and treatment arm interaction)
|
|
|
Venlafaxine response in generalised anxiety disorder (HAMA-A score reduction after 24 weeks)
|
|
|
Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 12 weeks)
|
|
|
Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks)
|
|
|
Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 12 weeks)
|
|
|
Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks)
|
|
|
Nevirapine-induced hypersensitivity in HIV (drug-induced liver injury)
|
|
|
Nevirapine-induced hypersensitivity in HIV (Stevens-Johnson syndrome or toxic epidermal necrosis)
|
|
|
Nevirapine-induced hypersensitivity in HIV
|
|
|
Acute graft versus host disease in bone marrow transplantation (recipient effect)
|
|
|
Acute graft versus host disease in bone marrow transplantation (donor effect)
|
|
|
Response to statins (HDL cholesterol change)
|
|
|
Waist circumference adjusted for BMI in inactive individuals
|
|
|
Waist-to-hip ratio adjusted for BMI in active individuals
|
|
|
Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan)
|
|
|
Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan)
|
|
|
Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan)
|
|
|
Western dietary pattern
|
|
|
Prudent dietary pattern
|
|
|
Theory of mind score in adolescence (Emotional Triangles Task)
|
|
|
Systolic blood pressure x smoking status (current vs non-current) interaction (1df test)
|
|
|
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test)
|
|
|
Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test)
|
|
|
Gout vs. Hyperuricemia
|
|
|
Body mass index (age <50)
|
|
|
Body mass index x age interaction
|
|
|
Waist-to-hip ratio adjusted for BMI (age <50)
|
|
|
Waist-to-hip ratio adjusted for BMI (age >50)
|
|
|
Body mass index (age>50)
|
|
|
Very low density lipoprotein cholesterol levels
|
|
|
Food allergy (parent-of-origin effect)
|
|
|
Peanut allergy (parent-of-origin effect)
|
|
|
Milk allergy (parent-of-origin effect)
|
|
|
Egg allergy (parent-of-origin effect)
|
|
|
Food allergy (maternal genetic effects)
|
|
|
Peanut allergy (maternal genetic effects)
|
|
|
Heart rate increase in response to exercise
|
|
|
Heart rate response to recovery post exercise (40 sec)
|
|
|
Heart rate response to recovery post exercise (30 sec)
|
|
|
Heart rate response to recovery post exercise (50 sec)
|
|
|
Heart rate response to recovery post exercise (10 sec)
|
|
|
Heart rate response to recovery post exercise (20 sec)
|
|
|
Milk allergy (maternal genetic effects)
|
|
|
Egg allergy (maternal genetic effects)
|
|
|
Sperm motility
|
Any process involved in the controlled movement of a sperm cell.
|
|
Blood osmolality (transformed sodium)
|
|
|
Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy)
|
|
|
Neuritic plaques or neurofibrillary tangles (pleiotropy)
|
|
|
Neuritic plaques or cerebral amyloid angiopathy (pleiotropy)
|
|
|
Neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy)
|
|
|
Body mass index x sex x age interaction (4df test)
|
|
|
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)
|
|
|
Waist-to-hip ratio adjusted for BMI x sex interaction
|
|
|
Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction)
|
|
|
Urinary magnesium-to-creatinine ratio
|
|
|
Serum magnesium levels
|
|
|
Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease
|
|
|
Lipoprotein phospholipase A2 activity in cardiovascular disease
|
|
|
Major coronary event in placebo-treated cardiovascular disease (time to event)
|
|
|
Major coronary event in cardiovascular disease (time to event) (darapladib treatment interaction)
|
|
|
Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event)
|
|
|
Diarrhoea in darapladib-treated cardiovascular disease (time to event)
|
|
|
GIP levels in response to oral glucose tolerance test (120 minutes)
|
|
|
Glucagon levels in response to oral glucose tolerance test (120 minutes)
|
|
|
Insulin levels in response to oral glucose tolerance test (fasting)
|
|
|
Glucagon levels in response to oral glucose tolerance test (fasting)
|
|
|
GIP levels in response to oral glucose tolerance test (fasting)
|
|
|
GLP-1 levels in response to oral glucose tolerance test (fasting)
|
|
|
Insulin levels in response to oral glucose tolerance test (30 minutes)
|
|
|
Insulin levels in response to oral glucose tolerance test (120 minutes)
|
|
|
GLP-1 levels in response to oral glucose tolerance test (120 minutes)
|
|
|
NHDL cholesterol to HDL cholesterol ratio
|
|
|
LDL cholesterol to HDL cholesterol ratio
|
|
|
Triglyceride to HDL cholesterol ratio
|
|
|
Lung function (maximal voluntary ventilation)
|
|
|
Decline in glucose metabolism in posterior cingulate cortex
|
|
|
Uncontrolled blood pressure in combination therapy (beta blocker and thiazide diuretic)
|
|
|
Diastolic blood pressure in combination therapy (beta blocker and thiazide diuretic)
|
|
|
Pulmonary arterial hypertension
|
|
|
Pursuit maintenance gain in psychotic disorders
|
|
|
Initial pursuit acceleration
|
|
|
Pursuit maintenance gain
|
|
|
Initial pursuit acceleration in psychotic disorders
|
|
|
Anti-saccade error rate in psychotic disorders
|
|
|
Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy
|
|
|
Breast cancer in childhood cancer survivors treated with more than 10 gray radiotherapy
|
|
|
Breast cancer in childhood cancer survivors
|
|
|
Heart rate response to beta blockers
|
|
|
Chronic venous disease
|
|
|
Diastolic blood pressure (cigarette smoking interaction)
|
|
|
Open-angle glaucoma and optic cup area
|
|
|
Open-angle glaucoma and vertical cup-disc ratio
|
|
|
Primary vesicoureteric reflux
|
|
|
Sepsis in extremely premature infants
|
|
|
Uric acid clearance
|
|
|
Diastolic blood pressure x alcohol consumption interaction (2df test)
|
|
|
Triacylglycerol 56:6 levels
|
|
|
Tyrosine levels
|
|
|
Malate levels
|
|
|
Metabolite risk score for predicting weight gain
|
|
|
Sphingomyelin 24:0 levels
|
|
|
Triacylglycerol 56:2 levels
|
|
|
Niacinamide levels
|
|
|
Parental longevity (combined parental attained age, Martingale residuals)
|
|
|
Parental longevity (both parents in top 10%)
|
|
|
Parental longevity (mother's age at death)
|
|
|
Mental health study participation (provided email address)
|
|
|
Mental health study participation (completed survey)
|
|
|
Diabetic maculopathy with decreased visual acuity in type 2 diabetes
|
|
|
HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)
|
|
|
Triglyceride levels in current drinkers
|
|
|
Mild to moderate chronic kidney disease
|
|
|
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)
|
|
|
Response to SSRI (symptom remission)
|
|
|
Response to antidepressants (symptom remission)
|
|
|
Parental longevity (mother's attained age)
|
|
|
Parental longevity (father's age at death)
|
|
|
Parental longevity (father's attained age)
|
|
|
Bone mineral density (lumbar spine) in inflammatory bowel disease
|
|
|
Bone mineral density (femoral neck) in inflammatory bowel disease
|
|
|
Parental longevity (combined parental age at death)
|
|
|
Appendectomy
|
|
|
Regular attendance at a gym or sports club
|
|
|
Regular attendance at a pub or social club
|
|
|
Ability to confide in someone
|
|
|
Regular attendance at a religious group
|
|
|
Loneliness (MTAG)
|
|
|
Hippocampal volume in mild cognitive impairment
|
|
|
Logical memory (immediate recall) in mild cognitive impairment
|
|
|
Logical memory (delayed recall) in mild cognitive impairment
|
|
|
Cerebrospinal AB1-42 levels in normal cognition
|
|
|
Logical memory (immediate recall) in Alzheimer's disease dementia
|
|
|
Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia
|
|
|
Logical memory (delayed recall) in Alzheimer's disease dementia
|
|
|
Cerebrospinal AB1-42 levels in mild cognitive impairment
|
|
|
Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia
|
|
|
Cerebrospinal fluid t-tau levels in mild cognitive impairment
|
|
|
Hippocampal volume in Alzheimer's disease dementia
|
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Cerebrospinal fluid p-tau levels in mild cognitive impairment
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Cerebrospinal fluid t-tau levels in normal cognition
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Cerebrospinal fluid p-tau levels in normal cognition
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Hippocampal volume in normal cognition
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Logical memory (immediate recall) in normal cognition
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Logical memory (delayed recall) in normal cognition
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Cerebrospinal fluid p-tau levels
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Logical memory (immediate recall)
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Logical memory (delayed recall)
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Childhood dental caries in primary teeth
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Childhood dental caries in permanent teeth
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Fatty acid desaturase activity (serum)
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Fatty acid desaturase activity (adipose tissue)
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Diabetic retinopathy (all NPDR and PDR)
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Alcohol withdrawal symptoms
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LDL cholesterol levels in current drinkers
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HDL cholesterol levels in current drinkers
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Benign prostatic hyperplasia and lower urinary tract symptoms
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Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)
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Chronic mountain sickness
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LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)
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Number of alcoholic drinks required to feel an effect (first five times drinking)
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Number of alcoholic drinks required to feel an effect (long-term average)
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Platelet reactivity measurement (collagen-ADP)
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Platelet reactivity measurement (collagen-epinephrine)
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End-stage kidney disease
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Left ventricular mass x antihypertensive treatment interaction
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Relative wall thickness x antihypertensive treatment interaction
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Systemising
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Treatment resistant depression
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Depressive symptom improvement
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Schizophrenia vs type 2 diabetes
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Schizophrenia and type 2 diabetes
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PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia
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Attention function
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Verbal memory
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Reasoning
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Thinking that is coherent and logical.
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Fasting glucose change
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Fasting glucose change (long-term)
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Fasting glucose change (short-term)
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Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils)
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Hearing loss in Charcot-Marie-Tooth disease 1A
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Non-muscle-invasive bladder cancer tumour size
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Urinary sodium excretion
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Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy)
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Alcoholic chronic pancreatitis
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Breast cancer, ovarian cancer or prostate cancer (pleiotropy)
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Modified Stumvoll Insulin Sensitivity Index (BMI interaction)
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Modified Stumvoll Insulin Sensitivity Index
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Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI)
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Spontaneous dizygotic twinning
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Serum sulfate level
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Caudate volume in trauma-exposed individuals
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Nucleus accumbens volume in trauma-exposed individuals
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Lateral ventricle volume in trauma-exposed individuals
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Duloxetine response in major depressive disorder (% change in symptom score)
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Placebo response in major depressive disorder (% change in symptom score)
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B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio
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Midregional pro atrial natriuretic peptide levels
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N-terminal pro B-type natriuretic peptide levels
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Branched-chain amino acid levels (Isoleucine)
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Branched-chain amino acid levels (Leucine)
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Branched-chain amino acid levels (Valine)
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Common carotid intima-media thickness in HIV negative individuals
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Common carotid intima-media thickness in HIV infection
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Common carotid intima-media thickness
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High altitude adaptation
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Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes
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Intelligence (MTAG)
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Serum uric acid levels in response to allopurinol in gout
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Response to metformin in type 2 diabetes (HbA1c reduction)
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Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)
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Immunoglobulin A vasculitis
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Recurrent major depressive disorder
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Thrombin-activatable fibrinolysis inhibitor levels
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disease cluster belonging to disease group hematological
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Thrombin-activatable fibrinolysis inhibitor activation peptide
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Obsessive-compulsive disorder or autism spectrum disorder
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Lower body strength
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Circulating chemerin levels
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Matrix metalloproteinase-8 levels
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Subcutaneous adipose tissue (sex interaction)
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Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes
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Coronary artery calcified atherosclerotic plaque score in type 2 diabetes
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Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1)
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Differentiated thyroid cancer
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Papillary thyroid cancer
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disease cluster belonging to disease group cancer
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Forced expiratory volume in 1 second (environmental tobacco smoke interaction)
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Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes
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HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes
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LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes
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Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes
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QT interval (ambient particulate matter interaction)
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Apolipoprotein A-IV levels
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Bronchial hyperresponsiveness in asthma
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Benign prostatic hyperplasia and/or lower urinary tract symptoms
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Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer
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Methotrexate-induced interstitial lung disease in rheumatoid arthritis
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Lobe attachment (rater-scored or self-reported)
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Lobe attachment (rater scored)
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Alloimmunization response to pregnancy (HLA class I)
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Cardiometabolic and hematological traits
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Huntington's disease progression
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Sarcoidosis (non-Lofgren's syndrome)
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Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations)
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Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)
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Epstein-Barr virus copy number in lymphoblastoid cell lines
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B cell acute lymphoblastic leukaemia (normal cytogenetics)
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B cell acute lymphoblastic leukaemia (hyperdiploid negative)
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B cell acute lymphoblastic leukaemia (Philadelphia chromosome negative)
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B cell acute lymphoblastic leukaemia (abnormal cytogenetics)
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B cell acute lymphoblastic leukaemia in young adulthood
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B cell acute lymphoblastic leukaemia in adulthood
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Sarcoidosis (Lofgren's syndrome)
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Taxane-induced peripheral neuropathy in breast cancer
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Brain volume in infants (white matter)
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Brain volume in infants (cerebrospinal fluid)
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Brain volume in infants (grey matter)
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Brain volume in infants (intracranial brain volume)
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Ratio of apolipoprotein A1 to apolipoprotein B
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Esterified cholesterol levels
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Free cholesterol levels
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Total cholesterol levels in HDL
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Total cholesterol levels in LDL
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TB-LM or TBLH-BMD (pleiotropy)
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Severe gingival inflammation
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Relapse in multiple sclerosis
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Familial hepatitis B virus-related hepatocellular carcinoma
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Language performance in older adults (adjusted for episodic memory)
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Foot ulcer in diabetes and neuropathy
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Cognitive ability (MTAG)
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Cognitive ability
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Subjective response to lithium treatment
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Subjective response to lithium treatment in bipolar disorder
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Objective response to lithium treatment
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Objective response to lithium treatment in bipolar disorder
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Interleukin-1-receptor antagonist levels
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Response to exercise (triglyceride level interaction)
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Luteinizing hormone levels in polycystic ovary syndrome
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Testosterone levels in polycystic ovary syndrome
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Helping behaviour (self reported)
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Neovascular age-related macular degeneration
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Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction)
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Sporadic neuroblastoma
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Bone fracture in osteoporosis
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P wave terminal force
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Rubella-specific interleukin-6 secretion
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Low vWF levels
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Estrone levels
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Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy
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Atazanavir levels
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Opioid requirements during laparoscopic-assisted colectomy
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Waist-to-hip ratio adjusted for BMI in inactive individuals
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Plasma trimethylamine N-oxide levels
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Cleft palate
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An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.
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Response to radiotherapy in prostate cancer (toxicity, urinary frequency)
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Toxicity response to radiotherapy in prostate cancer (decreased urine stream) (time to event)
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Immunoglobulin light chain (AL) amyloidosis (liver involvement)
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Immunoglobulin light chain (AL) amyloidosis (serum Ig lambda profile)
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Immunoglobulin light chain (AL) amyloidosis (serum IgG profile)
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Vitamin D levels (dietary vitamin D intake interaction)
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Plasma kynurenine levels in major depressive disorder
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Plasma kynurenine to tryptophan ratio in major depressive disorder
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Clinically amyopathic dermatomyositis
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Disease progression in age-related macular degeneration
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Disease progression in age-related macular degeneration (adjusted for baseline)
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Disease progression to geographic atrophy form in age-related macular degeneration
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Disease progression to choroidal neovascularization form in age-related macular degeneration
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Phospholipid levels in medium VLDL
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Very large VLDL particle concentration
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Brain glucose metabolism (fluorodeoxyglucose uptake)
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Maximum habitual alcohol consumption
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Anti-Toxoplasma gondii IgG seropositivity
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Keratinocyte cancer (MTAG)
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Infant, child and juvenile death in continuous marriage (proportion of children died <15 years)
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Number of stillbirths in continuous marriage
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Oxygenated hemoglobin levels
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Number of live births
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Nonobstructive coronary artery disease
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Multiple sclerosis and systolic blood pressure (pleiotropy)
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Multiple sclerosis and body mass index (pleiotropy)
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Multiple sclerosis and waist-to-hip-ratio (pleiotropy)
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Multiple sclerosis and type 2 diabetes (pleiotropy)
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Multiple sclerosis and C-reactive protein levels (pleiotropy)
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Multiple sclerosis and triglyceride levels (pleiotropy)
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Multiple sclerosis and LDL levels (pleiotropy)
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Multiple sclerosis and HDL levels (pleiotropy)
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Angiotensin-converting enzyme inhibitor intolerance
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Multiple keratinocyte cancers
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Gait speed in old age
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Asthma or allergic disease (pleiotropy)
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Type 2 diabetes (age of onset)
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Depressive symptom measurement or major depressive disorder
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Possible neuropathic pain in post total joint replacement surgery for osteoarthritis
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Heparin-induced thrombocytopenia
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Low platelet count following administration of unfractionated or (less commonly) low-molecular weight heparin.
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T wave morphology restitution during exercise (MTAG)
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T wave morphology restitution during exercise
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T wave morphology restitution during recovery from exercise
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T wave morphology restitution during recovery from exercise (MTAG)
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Minimum ankle–brachial index
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Change in quality of life in response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease
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Response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease
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Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure
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Chromosomal aberration frequency (total)
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High chromosomal aberration frequency (chromatid type)
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Chromosomal aberration frequency (chromatid type)
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High chromosomal aberration frequency (chromosome type)
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Chromosomal aberration frequency (chromosome type)
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High chromosomal aberration frequency (total)
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High chromosomal aberration frequency (chromatid type) in genotoxic compound exposure
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Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure
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High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure
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Change in neurofilament light levels
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Tendinopathy
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Peripheral artery disease (borderline)
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Fagerstrӧm test for nicotine dependence
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Time to smoke first cigarette in the morning
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Hydrolysed wheat protein allergy
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Bipolar II disorder
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Sweet taste perception in obesity with metabolic syndrome
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Salty taste perception in obesity with metabolic syndrome
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Sour taste perception in obesity with metabolic syndrome
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Umami taste perception in obesity with metabolic syndrome
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Taste perception (total score including 6-n-propylthiouracil) in obesity with metabolic syndrome
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Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome
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Bitter taste perception (phenylthiocarbamide) in obesity with metabolic syndrome
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Severe gastric atrophy
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Pepsinogen I/II ratio
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Gastric atrophy
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HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)
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Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)
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Parental longevity (mother's age at death or mother's attained age)
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Liver disease biomarker
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Verbal cognitive ability
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Numerical cognitive ability
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Figural/spatial cognitive ability
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Moderate-to-late spontaneous preterm birth
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Spontaneous preterm birth with premature rupture of membranes
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Spontaneous preterm birth without premature rupture of membranes
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Gestational age at birth (child effect)
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Early spontaneous preterm birth
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Asthma and attention deficit hyperactivity disorder
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Asthma and major depressive disorder
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Response to allopurinol in gout (change in serum uric acid levels)
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Cytokine levels
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Cytokine network levels (multivariate analysis)
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Subpleural-predominant interstitial lung abnormalities
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Interstitial lung abnormalities
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Antipsychotic drug-induced weight gain in schizophrenia
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Antipsychotic drug-induced weight gain in schizophrenia or autism
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Phenylephrine infusion rate during anesthesia
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Number of decayed, missing and filled tooth surfaces or use of dentures
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Number of decayed, missing and filled tooth surfaces
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Dentures
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Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis)
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Plasma anti-thyroid peroxidase levels
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Plasma anti-thyroglobulin levels
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Post-term birth
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Response to adalimumab in hidradenitis suppurativa (abscess and inflammatory nodule count increase)
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High-grade serous ovarian cancer
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Epigenetic age acceleration in alcohol use disorder
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Alcohol dependence or heroin dependence or methamphetamine dependence
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Rate of ventricular enlargement
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Pancreatic ductal adenocarcinoma
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A pancreas adenocarcinoma that derives_from pancreatic duct cells.
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Age-related cognitive decline (global cognition) (slope of z-scores)
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Age-related cognitive decline (executive function) (slope of z-scores)
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Age-related cognitive decline (language) (slope of z-scores)
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Age-related cognitive decline (memory) (slope of z-scores)
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Planum temporale asymmetry index
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Urinary potassium excretion
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Chronic lymphocytic leukemia or multiple sclerosis
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Diffuse large B-cell lymphoma or multiple sclerosis
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Follicular lymphoma or multiple sclerosis
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Marginal zone lymphoma or multiple sclerosis
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Chronic lymphocytic leukemia or rheumatoid arthritis
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Diffuse large B-cell lymphoma or rheumatoid arthritis
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Follicular lymphoma or rheumatoid arthritis
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Marginal zone lymphoma or rheumatoid arthritis
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Chronic lymphocytic leukemia or systemic lupus erythematosus
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Diffuse large B-cell lymphoma or systemic lupus erythematosus
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Marginal zone lymphoma or systemic lupus erythematosus
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Plasma factor V levels in venous thrombosis
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Plasma factor V levels in venous thrombosis (conditioned on rs6027)
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Non-lobar intracerebral hemorrhage
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Lobar intracerebral hemorrhage
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Non-lobar intracerebral hemorrhage (MTAG)
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Estimated glomerular filtration rate reduction (30%)
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Incident chronic kidney disease
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Neuroblastoma or malignant cutaneous melanoma
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Recurrence of malaria infection (mild or asymptomatic)
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Recurrence of mild malaria attacks
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Body mass index variance
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Basal metabolic rate variance
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Waist circumference variance
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Hip circumference variance
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Lung function (FEV1/FVC) variance
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Heel bone mineral density variance
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Birth weight variance
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Body fat percentage variance
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Macroalbuminuria in type 1 diabetes
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Microalbuminuria in type 1 diabetes
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Chronic kidney disease (reduced eGFR or end stage renal disease) in type 1 diabetes
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Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes
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Kidney disease (reduced eGFR and albuminuria or end stage renal disease) in type 1 diabetes
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Kidney disease (end stage renal disease or albuminuria) in type 1 diabetes
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Longevity (age >90th survival percentile)
|
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Longevity (age >99th survival percentile)
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Stress sensitivity (neuroticism score x major depressive disorder status interaction)
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|
Asthma (time to onset)
|
|
|
Degraded stimulus continuous performance test score
|
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|
Letter-number span reordering
|
|
|
Prepulse inhibition of the startle response
|
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|
Antisaccade task score
|
|
|
Abstraction and mental flexibility
|
|
|
Face memory
|
|
|
Sensorimotor dexterity
|
|
|
California verbal learning test score
|
|
|
Spatial processing
|
|
|
Spatial memory
|
|
|
Retinal arteriolar tortuosity
|
The presence of an increased number of twists and turns of the retinal arterioles.
|
|
Maximum retinal arteriolar tortuosity
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Retinal venular tortuosity
|
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Maximum retinal venular tortuosity
|
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|
Retinal arteriole-to-venule ratio
|
|
|
Optic disc radius
|
|
|
Skin aging measurement
|
|
|
Early onset periodontitis x smoking status interaction
|
|
|
Working memory
|
|
|
Cognitive performance (processing speed)
|
|
|
Schizophrenia or schizoaffective disorder
|
|
|
Non-accommodative esotropia
|
|
|
Longitudinal cocaine use
|
|
|
White coat effect (clinic systolic blood pressure minus ambulatory systolic blood pressure)
|
|
|
White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure)
|
|
|
Age at suicide
|
|
|
Dental caries (decayed, missing and filled teeth)
|
|
|
Dental caries (decayed and filled deciduous teeth)
|
|
|
Dental caries (decayed, missing and filled tooth surfaces)
|
|
|
Dental caries (decayed and filled deciduous tooth surfaces)
|
|
|
Childhood absence epilepsy
|
A childhood electroclinical syndrome that is characterized by brief and frequent absence seizures in children with age of onset between four and ten years.
|
|
Juvenile myoclonic epilepsy
|
A adolescence-adult electroclinical syndrome that is characterized by brief, involuntary twitching of a muscle or a group of muscles (myoclonus) early in the morning with onset between 12 and 18 years.
|
|
Focal epilepsy (with hippocampal sclerosis)
|
|
|
Focal epilepsy
|
An epilepsy syndrome that is characterised by seizures that are preceded by an isolated disturbance of a cerebral function and arise from an epileptic focus, a small portion of the brain that serves as the irritant driving the epileptic response.
|
|
B6 vitamer levels (multivariate analysis)
|
|
|
Cerebrospinal fluid pyridoxal phosphate levels
|
|
|
Plasma pyridoxal phosphate levels
|
|
|
Cerebrospinal fluid pyridoxal phosphate to pyridoxal ratio
|
|
|
Plasma pyridoxic acid to pyridoxal phosphate ratio
|
|
|
Response to ketamine in bipolar disorder or major depression (antidepressant effects)
|
|
|
Response to ketamine in bipolar disorder or major depression (dissociation effects)
|
|
|
Age-related cognitive decline (visuospatial skill) (slope of z-scores)
|
|
|
Age-related cognitive decline (attention/processing speed) (slope of z-scores)
|
|
|
Red vs. brown/black hair color
|
|
|
Blond vs. brown/black hair color
|
|
|
Brown vs. black hair color
|
|
|
Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies)
|
|
|
Response to beta blocker use in hypertension (systolic blood pressure)
|
|
|
Adventurousness
|
|
|
Smoking status (ever vs never smokers)
|
|
|
Automobile speeding propensity
|
|
|
Number of sexual partners
|
|
|
General risk tolerance (MTAG)
|
|
|
Risk-taking tendency (4-domain principal component model)
|
|
|
Severe insulin-deficient type 2 diabetes
|
|
|
Severe insulin-resistant type 2 diabetes
|
|
|
Severe autoimmune type 2 diabetes
|
|
|
Mild obesity-related type 2 diabetes
|
|
|
Mild age-related type 2 diabetes
|
|
|
Alcohol-related hepatocellular carcinoma
|
|
|
Systemic vasculitis
|
|
|
Age at menarche
|
The age of onset of (human) menarche, the beginning of the first menstrual cycle in an individual
|
|
Cisplatin-induced hearing loss in childhood cancer
|
|
|
Chronic widespread musculoskeletal pain
|
|
|
Arthritis (oligoarticular juvenile idiopathic)
|
|
|
Amyloid beta positivity
|
|
|
Peak height velocity
|
|
|
Hypoalbuminemia
|
Reduction in the concentration of albumin in the blood.
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Albuminuria
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The presence of albumin in the urine, an indicator of KIDNEY DISEASES.
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Extrahepatic cholangiocarcinoma
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Cerebral amyloid angiopathy in APOEe4 carrier Alzheimer’s disease
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Cerebral amyloid angiopathy in APOEe4 non-carrier Alzheimer’s disease
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Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease
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Cerebral amyloid angiopathy in Alzheimer’s disease
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Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease
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Fasting insulin
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Facial skin colour (CIELAB index L* value)
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Facial skin colour (CIELAB index b* value)
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Serum vitamin D-binding protein levels in type 2 diabetes
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Bioavailable vitamin D levels in type 2 diabetes
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Hemoglobin levels in non-alcoholic fatty liver disease x mastiha supplementation interaction
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Total antioxidant status in non-alcoholic fatty liver disease x mastiha supplementation interaction
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Interleukin-6 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction
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Interleukin-6 gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction
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TNF-alpha gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction
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Interleukin-10 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction
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Glutathione peroxidase in non-alcoholic fatty liver disease x mastiha supplementation interaction
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Bipolar disorder (early vs late onset)
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Bullous pemphigoid
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An autoimmune disease of skin and connective tissue characterized by large blisters.
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Anterior thalamic nuclei volume
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Intralaminar thalamic nuclei volume
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Lateral thalamic nuclei volume
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Medial thalamic nuclei volume
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Posterior thalamic nuclei volume
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Ventral thalamic nuclei volume
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hemolysis of donated blood (osmotic)
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hemolysis of donated blood (oxidative)
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hemolysis of donated blood (cold-storage)
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Motor coordination
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Haemorrhoidal disease
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Cervical intraepithelial neoplasia grade 3
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disease cluster belonging to disease group cancer
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Invasive cervical cancer
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Cervical intraepithelial neoplasia grade 3 and invasive cervical cancer
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Vitamin C levels
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Retinitis pigmentosa
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A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.
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Congenital heart disease (transposition of the great arteries)
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Congenital heart disease (septal defects)
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Congenital right-sided heart lesions
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Congenital heart disease (anomalies of thoracic arteries and veins)
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Intestinal permeability measurement
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Chronic obstructive pulmonary disease x ever smoker interaction (2df)
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Chronic obstructive pulmonary disease in ever smokers
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Skin and soft tissue infections
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Periodontitis (stage III/IV grade C)
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Erythropoietin levels
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S100 calcium-binding protein levels
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Thymus and reactivation regulated chemokine levels
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Longevity (100 years and older)
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Brain asymmetrical skew (horizontal)
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Brain asymmetrical skew (vertical)
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Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics
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Surgical recurrence in Crohn's disease
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Serum urate levels
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Heel bone mineral density x serum urate levels interaction
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Femur bone mineral density x serum urate levels interaction
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Symptoms in placebo-treated COVID-19 outpatients at risk of severe disease (time to remission)
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L1-L4 bone mineral density x serum urate levels interaction
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Schizophrenia, bipolar disorder or major depressive disorder x sex interaction
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Schizophrenia, bipolar disorder or major depressive disorder
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Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df)
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Recurrent major depressive disorder x sex interaction
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Major depressive disorder x sex interaction
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Bipolar disorder x sex interaction
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Schizophrenia x sex interaction
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Frailty index
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Cocaine dependence (time to event)
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Opioid dependence (time to event)
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Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction
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Schizophrenia, bipolar disorder or recurrent major depressive disorder
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ICD10 Z72.0: Tobacco use
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Bevacizumab-induced hypertension
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Bevacizumab-induced proteinuria
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Bevacizumab-induced composite toxicity (either hypertension or proteinuria)
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Alcohol drinking status (current drinker vs non-current drinker)
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Sociability score
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Attending social / leisure activities
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Hypertensive renal disease
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Plasma amyloid beta peptide concentration (ABx-40/ABx-42 ratio)
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Chronic obstructive pulmonary disease x current smoker interaction (2df)
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Chronic obstructive pulmonary disease x ever smoker interaction (1df)
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Chronic obstructive pulmonary disease in non-current smokers
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SAPHO syndrome
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Severe coronary stenosis (young age of onset interaction)
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Suicide attempt severity in mood disorders
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Suicidality in mood disorders
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Chronic obstructive pulmonary disease x current smoker interaction (main effect)
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Chronic obstructive pulmonary disease x current smoker interaction (1df)
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Chronic obstructive pulmonary disease in current smokers
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Sun-seeking behavior
|
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Response to antioxidants and zinc in age-related macular degeneration (disease progression)
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Psoriasis or type 2 diabetes (trans-disease meta-analysis)
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Language functional connectivity
|
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Depression x maternal smoking during pregnancy interaction
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Anxiety x maternal smoking during pregnancy interaction
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Survival time in esophageal squamous cell carcinoma
|
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Spleen volume
|
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Liver volume
|
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Pancreas volume
|
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Kidney volume
|
|
|
Visceral adipose tissue volume
|
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Abdominal subcutaneous adipose tissue volume
|
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Percent liver fat
|
|
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Liver iron content
|
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Lung volume
|
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Pancreas fat
|
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|
Tonsillitis
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An upper respiratory tract disease which involves inflammation of the tonsils resulting from bacterial (Group A streptococcus) and viral (Epstein-Barr virus, adenovirus) infections. Symptoms include a severe sore throat (which may be experienced as referred pain to the ears), painful/difficult swallowing, coughing, headache, myalgia (muscle aches), fever and chills. Tonsillitis is characterized by signs of red, swollen tonsils which may have a purulent exudative coating of white patches (i.e. pus). Swelling of the cheeks and neck may occur.
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