HPA Cell Line Gene Expression Profiles Dataset

Description RNA-seq gene expression profiles for cell lines from HPA
Measurement gene expression by RNA-seq
Association gene-cell line associations by differential expression of gene across cell lines
Category transcriptomics
Resource Human Protein Atlas
Citation(s)
Last Updated 2015 Apr 06
Stats
  1. 15372 genes
  2. 43 cell lines
  3. 102943 gene-cell line associations

Data Access

API
Script

Visualizations

  • Attribute Similarity

  • Gene Attribute

  • Gene Similarity

cell line Gene Sets

43 sets of genes with high or low expression in each cell line relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.

Gene Set Description
a431 Human epidermoid carcinoma established from the solid tumor of an 85-year-old woman; cells were reported to have large numbers of EGF binding sites; cell line was used as indicator cell line for anti-TGF binding.
a549 Human lung carcinoma established from an explanted lung tumor which was removed from a 58-year-old Caucasian man in 1972; cells were described to induce tumors in athymic mice and to synthesize lecithin.
an3ca
bewo A immortal human cell line cell that has the characteristics: It was initiated from a malignant gestational choriocarcinoma of the fetal placenta. Need to check response to hormones before use. Back up culture of ECA2687.
bj
caco2 A immortal human colon-derived cell line cell that has the characteristics: Human colon carcinoma. Backup of ECA86010202.
capan2
daudi A immortal human blood cell line cell that has the characteristics: Burkitt's lymphoma. Sensitive to lymphokine-activated killer cells but resistant to natural killer cells. Back up culture of ECA3011.
efo21 disease: cystoadenocarcinoma
hacat
hek293 Established from a human primary embryonal kidney transformed by adenovirus type 5.
hel Human erythroleukemia, established from the peripheral blood of a 30-year-old man with erythroleukemia (AML M6) in relapse (after treatment for Hodgkin's disease) in 1980; cells were described to be capable of spontaneous and induced globin synthesis.
hela Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951. Later diagnosis changed to adenocarcinoma, first aneuploid, continuously cultured human cell line.
hepg2 Human hepatocellular carcinoma, established from the tumor tissue of a 15-year-old argentine boy with hepatocellular carcinoma in 1975.
hl60 Human acute myeloid leukemia established from the peripheral blood of a 35-year-old woman with acute myeloid leukemia (AML FAB M2) in 1976.
hmc1 Human mast cell line.
k562 Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970.
karpas707 cell line derived from haematopoietic_and_lymphoid_tissue
km3 Human pre-B lymphocytic leukemia cell line.
mcf7 A immortal human breast-derived cell line cell that has the characteristics: Human cell line derived from breast adenocarcinoma. TKG0479 (Deposited from Tohoku Univ.).
molt4
nb4
nes nestin|This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011]
ntera2 A human embryonal carcinoma (EC) stem cell line used as a model system for the study of neuronal differentiation
pc3
rh30 Human alveolar rhabdomyosarcoma cell line.
rpmi8226
rt4 Human urinary bladder transitional cell carcinoma; established from a recurrent well-differentiated transitional papillary tumor of the urinary bladder (clinical stage T2, histological grade G1, treated with gold grains 2 years earlier and diathermy after recurrence 10 months later) of a 63-year-old man in 1968.
sclc21h disease: carcinoma, small cell
shsy5y
skbr3 Human breast adenocarcinoma cell line; established from a caucasian female 43 years old. Morphology: epithelial-like.
skmel30 Human melanoma derived from tumor tissue (subcutis metastasis) of a 67-year-old Caucasian man with malignant melanoma in 1975.
t47d
thp1
u138mg Human glioblastoma cell line; established from a 47 years old human male.
u2197
u251mg Human glioma cell line. Morphology: glial; Species: human; Tumor: glioma.
u266 Human multiple myeloma cell line; established from the peripheral blood of a 53-year-old man with IgE-secreting myeloma (refractory, terminal) in 1968.
u26684 cell line derived from haematopoietic_and_lymphoid_tissue
u698 cell line derived from haematopoietic_and_lymphoid_tissue
u87
u937
wm115