| Description | Kinase inhibitor targets from percent inhibition of kinases by small molecules measured using purified kinases |
| Measurement | chemical bioactivity |
| Association | kinase-small molecule associations by percent inhibition of kinase by small molecule |
| Category | physical interactions |
| Resource | LINCS KinomeScan |
| Last Updated | Mon Apr 06 00:00:00 UTC 2015 |
| Stats |
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| API | |
| Script | |
| Downloads |
Attribute Similarity
Gene Attribute
Gene Similarity
71 sets of kinases inhibited by small molecules from the KinomeScan Kinase Inhibitor Targets dataset.
| Gene Set | Description |
|---|---|
| GSK461364 | |
| XMD15-27 | |
| Momelotinib | |
| BMS345541 | |
| XMD11-85h | |
| HG-6-64-01 | |
| TAK-715 | |
| AS601245 | |
| GSK1059615 | A thiazolidinone that is the 5-{[4-(pyridin-4-yl)quinolin-6-yl]methylene} derivative of 1,3-thiazolidine-2,4-dione. A PI3K inhibitor |
| XMD8-92 | A dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a [2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino substituent. It is an inhibitor of the BMK1 kinase pathway. |
| CGP60474 | |
| CP466722 | |
| XMD13-2 | |
| GSK2126458 | |
| AZ-628 | |
| WZ-7043 | |
| PHA-767491 | |
| PLX-4720 | |
| BEZ235 | |
| Crizotinib | |
| KU63794 | |
| Neratinib | A quinoline compound having a cyano group at the 3-position, a 3-chloro-4-(2-pyridylmethoxy)anilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an ethoxy group at the 7-position. |
| Barasertib | |
| WZ3105 | |
| Lapatinib | |
| Sigma A6730 | |
| ZM-447439 | |
| NU7441 | |
| PD0332991 | |
| OTSSP167 | |
| XMD-12 | |
| AG1478 | |
| CP724714 | |
| SB590885 | |
| PLX4032 | |
| GSK429286A | |
| ZG-10 | |
| JNK-9L | |
| XMD16-144 | |
| Sorafenib | |
| CG-930 | |
| XMD11-50 | |
| 5z-7-oxozeaenol | A macrolide that is the 7-oxo derivative of zeaenol (the 5Z stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB. |
| JWE-035 | |
| GW843682 | |
| AZD4547 | A member of the class of benzamides that is a carboxamide resulting from the formal condensation of the carboxy group of 4-(cis-3,5-dimethylpiperazin-1-yl)benzoic acid with the amino substituent of 5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-amine. It is an inhibitor of the fibroblast growth factor receptor (FGFR). |
| BX-912 | |
| ALW-II-38-3 | |
| HG-14-8-02 | |
| THZ-2-98-01 | |
| Torin2 | |
| KIN001-220 | |
| MLN8054 | |
| CGP74514A | |
| PHA-793887 | |
| GDC-0941 | |
| Dabrafenib | An organofluorine compound and antineoplastic agent, used as its mesylate salt in treatment of metastatic melanoma. |
| XMD8-85 | |
| Bosutinib | |
| AZD 5438 | |
| BS-181 | |
| RO-3306 | |
| QL-XI-92 | |
| Dinaciclib | |
| Torin1 | A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. |
| (R)- Roscovitine | |
| AZD-6482 | |
| QL-X-138 | |
| WYE-125132 | |
| GW-5074 | |
| XMD14-99 |
