| Description | Sets of genes/proteins extracted from pathway figures in research publications using optical character recognition |
| Measurement | association by literature curation |
| Association | protein-pathway associations extracted from figures in published literature |
| Category | structural or functional annotations |
| Resource | Pathway Figure Optical Character Recognition |
| Citation(s) | |
| Last Updated | 2024 Oct 08 |
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Gene Attribute
Gene Similarity
Attribute Similarity
UMAP
35464 sets of proteins participating in pathways from the PFOCR Pathway Figure Association 2023 dataset.
| Gene Set | Description |
|---|---|
| PMC100005__F11 | Formation of TrkA-src-aPKC complexes |
| PMC101242__F7 | Up-regulation of RAD51 in 8-MOP-treated cells |
| PMC101920__F1 | Late steps of AdoCbl biosynthesis in S |
| PMC102186__F9 | Ras-mediated signaling pathways |
| PMC102215__F1 | Pathways to Lignin Monomers.The "metabolic grid" shown in this scheme incorporates the results of recent studies suggesting previously unexpected substrate specificities for F5H and COMT (; ; ) |
| PMC1052008__F1 | Activation of PI3K/Akt signaling in adaptive versus maladaptive hypertrophy |
| PMC1052008__F3 | GSK-3 as a convergence point in hypertrophic signaling |
| PMC1064894__F3 | Toll-like receptor (TLR) signaling pathways |
| PMC1065305__F1 | Components of the AhR-mediated lacZ reporter assay |
| PMC1069556__F6 | Effect of NS5A on the Beta-catenin signaling pathway |
| PMC1069621__F5 | Two models for coupling of circadian and cell cycles |
| PMC1082717__F1 | The mTOR pathway and the potential intersection with LMP2A-activated PI3-kinase/Akt signaling |
| PMC1083688__F2 | Curbing the nuclear activities of Beta-catenin |
| PMC1083933__F2 | Cell cycle trials in Salamanca |
| PMC1087229__F8 | Signaling pathway of NGF-induced neurite outgrowth in PC12 cells |
| PMC1087506__F8 | IRAK1 functions in the TLR and IL-1B pathway upstream of convergence with the TNFA pathway |
| PMC1087583__F5 | The secretory pathway and UPR under different conditions |
| PMC1087795__F1 | Schematic depiction of the S |
| PMC108819__F8 | Signalling pathways for EGF activation of c-jun |
| PMC1088370__F1 | Topologies of the three networks |
| PMC108887__F9 | The CD5-induced signaling pathway, which is mediated by PI 3-kinase and Vav, resulting in the activation of Rac1 |
| PMC1090600__F5 | Illustration of the Rel/NFKB pathway |
| PMC109251__F9 | Integration of growth factor-, retinoid-, and ECM-derived signaling pathways during normal mucosecretory cell differentiation |
| PMC111167__F1 | BR biosynthesis pathway |
| PMC1120573__F4 | Relation between some major controlling factors involved in apoptosis |
| PMC1124928__F4 | Coagulation, fibrinolysis, and angiogenesis in cancer |
| PMC1133795__F3 | Functions of NFKB1 and NFKB2 in immune cell biology |
| PMC1133850__F10 | Vaccinia virus-stimulated mitogen-activated protein kinase (MAPK) pathway is required for virus multiplication |
| PMC1134761__F4 | Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit |
| PMC1134985__F3 | Exploring the functions of RNA interference pathway proteins: some functions are more RISCy than others? |
| PMC1138975__S1 | High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts |
| PMC1138975__S2 | High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts |
| PMC1140402__F2 | The central carbon metabolism of E |
| PMC1142215__F2 | Models for the action of the Nck/Dock signaling pathways in R-cell growth cones |
| PMC1143566__F2 | A schematic diagram for the hedgehog (HH) signaling pathway |
| PMC1143566__F4 | Schematic diagram for the Wnt signaling pathway |
| PMC114459__F1 | Mechanisms of ISG induction |
| PMC115962__F5 | IFNG signaling pathway showing the defects in the human fibroblast mutants B3, B9, and B10 |
| PMC1160519__F6 | Cardiac glycosides inhibit TNFA/NFKB signaling by blocking recruitment of TRADD to the TNFR |
| PMC116060__F6 | Proposed signal transduction pathways involved in PKC-mediated SRE activation |
| PMC1168613__F1 | Comparison of the D |
| PMC1168797__F7 | Repair and/or tolerance of AFB1-induced DNA damage in S |
| PMC1168814__F8 | The regulation of replication-dependent histone H4 genes at the G1/S phase cell cycle transition via the cyclin E/CDK2/p220/HiNF-P pathway relative to the E2F/pRB pathway |
| PMC1169236__F2 | Metabolic reconstructions of the polyamine pathway based upon pam and sam analyses of poor-prognosis human NE tumors |
| PMC1172066__F8 | Model depicting how inner ear polarity is generated in response to extracellular signals |
| PMC1173149__F10 | TAp63Alpha-induced apoptosis |
| PMC1174965__F4 | Regulation of lipopolysaccharide (LPS) signaling by suppressor of cytokine signaling 1 (SOCS1) |
| PMC1175050__F1 | NFKB pathway regulates inflammation, dendritic cell (DC) development and function, and thymic selection and regulatory T cell production |
| PMC1176393__F2 | Regulatory network of stress responses to drought, salt, and cold: specificity and cross-talk |
| PMC1176468__F9 | Crosstalk model of ATF3 and c-myc in serum induction |
| PMC1180390__F5 | Signaling pathways implicating p120-RasGAP |
| PMC1182485__F8 | Schemes of the Ethylene Biosynthetic, Signaling, and Response Pathways.Key elements of the pathways are displayed in a linear manner and are connected by arrows |
| PMC1183194__F4 | Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin |
| PMC1183194__F5 | Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin |
| PMC1183194__F6 | Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin |
| PMC1183479__F8 | Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2) |
| PMC1186689__S1 | Interferon-Gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes |
| PMC1186734__F6 | Glucocorticoid Receptor-Dependent Gene Regulatory Networks |
| PMC1190322__F10 | CdGAP mediates cross talk between the Ras/MAPK pathway and the regulation of Rac1 activity |
| PMC1190355__F8 | A model of IRAK1c regulation of inflammation |
| PMC1193534__F1 | Comparative Genomics of Natural Killer Cell Receptor Gene Clusters |
| PMC1193608__F8 | Model of HAV interaction with the dsRNA-induced IRF-3 activation pathway |
| PMC1195384__F2 | Folate pathway in Plasmodium falciparum and the proposed mode of action of the diaminopteridines, analogs of folate precursors |
| PMC1195968__F1 | RSV binding and triggering of cellular responses |
| PMC1197416__F6 | Several signaling pathways converge to drive actin polarization |
| PMC1199368__F5 | Candidate genes that are involved with the metabolism of androgen and estrogen |
| PMC1201250__F7 | Mechanism of TgHSP70 tolerance in PMs from WT mice |
| PMC1201344__F4 | Fasting effects on fatty acid composition |
| PMC1201361__F6 | Anandamide as an intracellular messenger inducing Ca2+ influx via TRPV1 |
| PMC1201394__F4 | Cell Cycle Arrest and Cell Death Are Controlled by p53-dependent and p53-independent Mechanisms in Tsg101-deficient Cells |
| PMC1201514__F1 | Regulation of the PIS1-encoded Phosphatidylinositol Synthase in Saccharomyces cerevisiae by Zinc |
| PMC120783__F7 | GPI biosynthetic pathways in T |
| PMC1215521__F7 | Possible gene regulation in macrophage THP-1 stimulated by theophylline |
| PMC1216340__F10 | Schematic model depicting potential mechanism that might contribute to epithelial-specific regulation of the CFTR gene |
| PMC122866__F4 | The pathway of PUFA synthesis in C |
| PMC1234333__F7 | Knockdown of Smad4 affects only a subset of TGF-Beta-regulated target genes and functions |
| PMC1235815__F7 | Possible ATM pathways contributing to polyomavirus replication (see Discussion) |
| PMC1236692__F3 | Caspase signaling and its modulation |
| PMC1236696__F1 | IKK/NFKB signaling pathways |
| PMC1236698__F2 | Molecular mechanisms of autophagy |
| PMC1236700__F2 | Regulation of the extrinsic pathway by Hsps |
| PMC123677__F3 | The action of S-phase checkpoints in the suppression of spontaneous genome instability |
| PMC1237009__F1 | Will the Real Cholesterol Transporter Please Stand Up |
| PMC1237076__F7 | Wnt-NLK pathway inhibits the activity of Myb family of proteins by two different mechanisms |
| PMC124938__F7 | The proposed c-Kit signal transduction pathway in PGCs |
| PMC125938__F8 | An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype |
| PMC126023__F7 | Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae |
| PMC126171__F5 | Different telomere damage signaling pathways in human and mouse cells |
| PMC1262773__F4 | Endocrine regulation of the testis |
| PMC1280267__F7 | Model schema for the phosphorylation of CRMP-2 by Rho kinase, Cdk5, and GSK-3B |
| PMC128142__F1 | Proposed biosynthetic pathway of GPI in the ER of P |
| PMC1287678__F9 | Putative signaling pathway of the evolutionarily conserved Toll/NFKB pathway utilizing the E |
| PMC1288263__F2 | Mammalian sex determination: a molecular view |
| PMC1288546__F1 | Human SHH-PTCH-GLI pathway (left) and its links to human diseases (right) |
| PMC128926__F2 | Activation of the NFKB pathway by IL-1 |
| PMC129737__F5 | Model for repair of camptothecin-induced replicative damage |
| PMC1297571__F6 | Simplified diagram of the proposed signalling events leading to Cyp7b gene transcription in synovial fibroblasts |
| PMC1297590__F2 | Ubiquitination of key signaling in anergic T cells |
| PMC1297640__F1 | Systems and molecular complexity in glycobiology |
| PMC1297683__F3 | Final network resulting from applications of our integration method to the 18 types of evidence for yeast galactose utilization and a set of network analysis tools |
| PMC1304358__F3 | Examples of extreme signaling pathways of the JAK-STAT signaling network |
| PMC1304643__F2 | Probability flux distributions for human red blood cell |
| PMC1307592__F2 | Some of the negative feedback mechanisms discussed at the meeting |
| PMC1307593__F2 | A model of phytochrome signal transduction |
| PMC1312313__F8 | NO• regulation of the cell cycle |
| PMC1315902__F2 | Multiple roles for kinases in DNA replication |
| PMC1316260__F3 | Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway |
| PMC1316260__F6 | Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway |
| PMC1322299__F1 | Tweaking Microtubules to Treat Scleroderma |
| PMC1323499__F1 | New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor |
| PMC1326163__F4 | TSH-cAMP signaling pathway in thyrocytes and its negative feedback regulators |
| PMC1326326__F3 | Proposed regulation of Cdc25A at the G1 and intra-S-phase checkpoints |
| PMC1327675__F3 | Interactive map (pathway) of 46 genes/proteins created in PathwayAssist® from the list of transcripts up-regulated in the testes of ABP-transgenic mice |
| PMC1327682__F3 | Schematic overview of the Saccharomyces cerevisiae central carbon metabolism |
| PMC133602__F6 | The yeast glyoxylate bypass pathway and its possible connection with other predicted changes |
| PMC134648__F8 | Role of Axin2 in Wnt signal transduction |
| PMC1350949__F7 | Proposed model of the HCMV-induced apoptotic signaling pathways |
| PMC1351030__F8 | Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. |
| PMC1351175__F11 | Proposed Receptor Ck - dependent signaling pathway involved in hTERT gene regulation at the transcriptional level |
| PMC1351245__F1 | Delayed Dark Adaptation in 11-cis-Retinol Dehydrogenase-deficient Mice |
| PMC1352320__F1 | Genome Wide Analysis Reveals Inositol, not Choline, as the Major Effector of Ino2p-Ino4p and Unfolded Protein Response Target Gene Expression in Yeast |
| PMC1356334__F7 | Alignment of sequences adjacent to Y200 for human TRPV1-4 |
| PMC1359062__F1 | Ciliated cell differentiation into goblet cells requires 2 signals |
| PMC1361361__F7 | Shp-1 mediates the anti-proliferative activity of TIMP-2 in human microvascular endothelial cells |
| PMC136456__F7 | The modulation of cellular signaling pathways by NS5A |
| PMC1369209__F3 | Models for ECT-2 activation and its role in activating the EGFR/RAS/MAPK pathway |
| PMC137067__F1 | The Hedgehog signaling pathway |
| PMC137069__F1 | Hh-signaling pathway |
| PMC1371031__F4 | Model on Bcr effects on Beta-catenin |
| PMC137498__F6 | Regulation of Cdc25A by Chk1 |
| PMC1375233__F2 | Association between human TLRs and adaptors determine each TLR-specific signaling pathway |
| PMC1375233__F5 | Two signaling pathways of TLR in myeloid DCs |
| PMC1380241__F1 | CoQ10biosynthetic pathway with eight known biosynthetic enzymes denoted as COQ1-COQ8 |
| PMC1382215__F1 | The de novo arginine biosynthetic pathway |
| PMC1383482__F1 | Tumor Necrosis Factor by Microbial Pathogens |
| PMC1383515__F6 | Proposed tentative mechanism underlying MAFA-mediated selective inhibition of FcɛRI-induced cytokine gene transcription |
| PMC1383550__F2 | Two branches of the class I PI3K pathway |
| PMC1383660__F5 | Intracellular signalling pathways activated by leptin |
| PMC1383660__F6 | Intracellular signalling pathways activated by leptin |
| PMC1383714__F8 | Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling |
| PMC1386115__F3 | Integration of lipid metabolic and inflammatory signaling in macrophages by LXRs |
| PMC1386711__F4 | MAPK signaling pathway mapping |
| PMC138687__F1 | The TGFB signaling pathway, showing the activation cascade and points of inhibition (??) |
| PMC138693__F2 | Phosphoinositide 3-kinase (PI3K) signalling and cancer |
| PMC138723__F1 | Simplified model of some of the components of p53 signalling |
| PMC138773__F1 | EGFR transactivation by GPCRs and cytokine receptors |
| PMC138838__F1 | Signaling through mammalian and Drosophila Toll-family receptors (TLRs) |
| PMC1389768__F1 | The Challenge of Characterizing Operations in the Mechanisms Underlying Behavior |
| PMC1390683__F2 | Model illustrating a role of BRCA1 in the C2/M cell cycle checkpoint |
| PMC139100__F8 | Gelsolin-induced epithelial cell invasion is dependent on Ras-Rac signaling |
| PMC139153__F1 | Biosynthetic Pathway of JA.DAD1, the lipolytic enzyme, had long been sought and was identified in this study |
| PMC139401__F2 | TLR signal transduction pathways |
| PMC139433__F2 | Cell cycle arrest by transforming growth factor (TGF)B and their deregulation in cancer |
| PMC1395315__F1 | Methionine-Homocysteine metabolism and related pathways |
| PMC1395315__F5 | Elevated Homocysteine is associated with atherosclerosis |
| PMC1397816__F1 | Inhibition of canonical Wnt signalling pathway in the absence of Wnt signals |
| PMC1397816__F2 | Activation of canonical Wnt signalling pathway in the presence of Wnt signals |
| PMC1397816__F5 | Inhibition of Wnt signalling by a Fz-dependent pathway |
| PMC139817__F7 | Regulatory interactions between SRF and TCF |
| PMC139865__F12 | Innate immunity pathways in Drosophila |
| PMC140043__F8 | RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF |
| PMC140192__F7 | Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF |
| PMC140507__F1 | The PI 3-kinase pathway by RNAi |
| PMC140665__F8 | Interaction between the Wnt/Beta-catenin and Wnt/Ca2+ pathways |
| PMC140731__F6 | Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1 |
| PMC1409799__F4 | MAPK signaling pathways |
| PMC1410746__F3 | Genmapp view of the epidermal growth factor (EGF) signaling pathway |
| PMC1410804__F7 | Cdc42 regulates HF differentiation and cell-cell contacts in keratinocytes by modulating the turnover of Beta-catenin and plakoglobin |
| PMC1413672__F6 | Activation of PI3K signaling by PV |
| PMC1413813__F8 | The signaling pathway regulating the expressions of SMAlpha-actin, SM-MHC, and calponin in SMCs on polymerized collagen in response to PDGF-BB/IL-1B costimulation |
| PMC1415320__F6 | The proposed TGFB1 signaling mechanism that promotes EMT |
| PMC1420312__F5 | Impact of SV40 ST on the Notch, Wnt, and Hedgehog Pathways |
| PMC1421247__F3 | Molecular Biology of Barrett's Adenocarcinoma |
| PMC1421301__F1 | Interferon Regulatory Factor Expression in Human Breast Cancer |
| PMC1421310__F1 | High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells |
| PMC1431703__F5 | Comparison of results with the known response pathway |
| PMC1431720__F7 | Cytokine release in RAW 264.7 macrophages |
| PMC1434604__F1 | Sites of action for reactive oxygen species in the regulation of the insulin signaling pathway |
| PMC1435694__F1 | Chemistry of the retinoid cycle reactions in the vertebrate retina |
| PMC1435944__F6 | Graphical Interface for the KnowledgeNet of candidate genes for hypertension |
| PMC1436036__F12 | Core signaling pathway downstream from V2R occupation in IMCD |
| PMC1440308__F6 | Alternative Th network |
| PMC1440308__F7 | Alternative Th network |
| PMC1440398__F2 | CDC maturation upon virus infection |
| PMC1440856__F1 | Omega-6 and -3 fatty acids & Prostate Cancer |
| PMC1446957__F5 | In vitro keratinocyte mitosis |
| PMC1447421__F10 | Hypothetical model describing the roles of Rad18 and PolK in the BPDE-induced S-phase checkpoint |
| PMC1448211__F7 | Real time pathway analysis of cell-cycle related genes mediated via TS overexpression in HCT-C18 (TS+) cells using actual gene expression data |
| PMC1449579__F5 | F igure 5.– |
| PMC1449671__F4 | Conservation of the NFKB signaling pathway from horseshoe crab to human |
| PMC1450137__F4 | Proposed mechanisms underlying the control of Mesp2 expression |
| PMC1456930__F5 | The molecular pathways controlling AB generation during aging |
| PMC1456973__F6 | Aspartate and aspartate transport in the pathway of prostate citrate production |
| PMC1464269__F1 | Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies |
| PMC1475580__F1 | Sequence of events in ATM→ATR dependent signaling of DSBs in S/G2 cells |
| PMC1475884__F2 | TNF receptor (TNFR) pathway of signaling |
| PMC1479092__F1 | The mitochondrial generated ROS-mediated activation of the p38 MAPK stress response pathway |
| PMC1479345__F3 | Pathway analysis |
| PMC1479345__F4 | Pathway analysis |
| PMC1479345__F5 | How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome. |
| PMC1479345__F6 | Pathway analysis |
| PMC1479345__F7 | Pathway analysis |
| PMC1479816__F3 | Pathways involved in mesenchymal cell proliferation and differentiation induced by G protein coupled receptors (GPCRs) |
| PMC1480427__F1 | ω3 LC-PUFA and ω6 LC-PUFA biosynthetic pathways |
| PMC1480599__F7 | Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response |
| PMC1481516__F2 | Metabolic pathway and bioenergetics of net citrate production in prostate cells |
| PMC1481658__F11 | Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity |
| PMC1482580__F4 | EDA signaling in hair follicle development |
| PMC1482699__F5 | GenMAPP growth hormone (Gh) signaling pathway |
| PMC1483059__F10 | Peculiar structure of the juxtanuclear actin network |
| PMC1483149__F1 | Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony |
| PMC1483167__F1 | Liver X receptor opens a new gateway to StAR and to steroid hormones |
| PMC1487177__F7 | AKT-1/PKB Signaling |
| PMC1489534__F3 | Regulation of cell wall gene expression during the cell cycle (A) and in response to external stimuli (B) |
| PMC14940__F10 | A signaling pathway of c-Met for cell scattering |
| PMC149906__F5 | A model to explain the effects of varying Fgf8 dosage on cell survival |
| PMC1501017__F2 | Different pathways involved in apoptosis |
| PMC1501125__F1 | WNT Pathway in Colorectal Carcinomas Stratified by Microsatellite Instability |
| PMC1502028__F4 | EGFR and mTOR signaling network, and signaling mediator effects associated with rapamycin and/or EKI-785 treatments |
| PMC1502396__F1 | The interaction between the AR and the ErbB/MAPK pathway |
| PMC1502426__F1 | Chromophore regeneration in vertebrate and invertebrate photoreceptors |
| PMC1502453__F5 | Hoxc8-regulated transcriptional network in vivo |
| PMC1502529__F6 | Network modeling |
| PMC1503662__F7 | UV-induced apoptotic signaling pathway |
| PMC150381__F2 | Interplay of the major genetic alteration in pancreatic carcinoma with the cell cycle |
| PMC1508148__F1 | Pathway diagram of genes tested for association |
| PMC150988__F1 | JAK-STAT signaling and the generation of Th1 and Th2 cells |
| PMC151022__F1 | TGFB signaling pathway |
| PMC151039__F1 | The classical pathway for bile acid synthesis begins with CYP7A1, which converts cholesterol into 7Alpha-hydroxycholesterol |
| PMC151063__F9 | p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop |
| PMC151138__F1 | Signaling and transcriptional pathways of Th1 differentiation and the potential role of c-Rel |
| PMC151255__F5 | Sugar Sensing and Signaling in Plants |
| PMC151358__F5 | JNK-dependent apoptosis signaling pathway |
| PMC151822__F2 | Signaling UPR-mediated cell death |
| PMC1522081__F7 | Involvement of MACF1 in the Wnt/Beta-catenin signaling pathway |
| PMC1525002__F4 | Sequence logo [41] of putative regulatory motif |
| PMC1525228__F9 | Diagram depicting the mechanism by which NGF may inhibit GSK-3B and promote axon growth |
| PMC1525234__F6 | Working model of regulatory mechanisms controlling cell death in response to mating pheromones |
| PMC1526532__F1 | Genomic Analysis of the Opi- Phenotype |
| PMC1526546__F1 | Innate model of lupus pathogenesis: central role of TLR-activated MZ-B cells and pDCs |
| PMC1526596__F1 | P38 mitogen-activated protein kinase (MAPK) signaling cascade in T cells |
| PMC1526619__F1 | Wnt/Beta-catenin signaling pathway |
| PMC1526619__F2 | The canonical transforming growth factor (TGF)B/Smad signaling pathway |
| PMC152905__F6 | Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line |
| PMC1533821__F2 | Recognition of pathogens by cytosolic PRRs |
| PMC153558__F3 | Model of the maternal Radar signaling pathway mediating early steps of dorsoventral axis formation |
| PMC153613__F4 | Highlights of key changes in cell cycle, differentiation, and metabolism-related transcripts |
| PMC1538848__F3 | Expression data analysis and visualization on the PANTHER website |
| PMC1539153__F6 | Model for control of carbon source-dependent growth and development by GPR-4 and heterotrimeric G proteins in N |
| PMC1550314__S1 | Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells |
| PMC1550774__F6 | The role of EIN5 in the ethylene signal transduction pathway |
| PMC1551980__F1 | Ubiquitin Signaling in the NFKB Pathway |
| PMC1551980__F3 | Ubiquitin Signaling in the NFKB Pathway |
| PMC1551980__F4 | Ubiquitin Signaling in the NFKB Pathway |
| PMC155294__F4 | Representation of the cell cycle control pathway within TIGR Orthologous Gene Alignment (TOGA) |
| PMC1553197__F8 | Model of CISK-mediated inhibition of CXCR4 sorting and degradation |
| PMC155330__F7 | slpr, encoding Drosophila MLK, is the MKKK for the Jun kinase pathway during dorsal closure in the fly |
| PMC1553448__F7 | Transcript expression of BMP signaling pathway members |
| PMC155355__F7 | Model outlining the roles of GAI/RGA-like GA-signaling components in the plant life cycle |
| PMC155392__F3 | Predicted pathways for degradation, transport, and metabolism of chitin by M |
| PMC1555642__F1 | Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin |
| PMC1555658__F2 | Cholesterol precursors and facial clefting |
| PMC155638__F1 | MAP kinase signalling pathways |
| PMC155638__F3 | Hypoxic activation of apoptosis pathways |
| PMC1557712__F2 | Molecular control of alveolar morphogenesis |
| PMC1557825__F4 | Ordering and correlation network diagrams for the significant pathways |
| PMC1559555__F1 | GSH metabolic pathway |
| PMC1559676__F1 | The unfolded protein response |
| PMC1560089__F7 | Proposed LITAF signaling pathway |
| PMC1564158__F2 | Predicting Essential Components of Signal Transduction Networks: A Dynamic Model of Guard Cell Abscisic Acid Signaling |
| PMC1564204__F6 | Schematic pathway of lipid turnover induced by Pi stress |
| PMC156758__F1 | NEW EMBO MEMBER'S REVIEW |
| PMC156764__F1 | NEW EMBO MEMBER'S REVIEW |
| PMC1569532__F1 | Different types of regulatory T cells |
| PMC1570177__F1 | Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability |
| PMC1571066__F2 | TGFB superfamily signalling pathway (see text for explanation) |
| PMC1571066__F5 | Model of SMAD7 role in control of blood vessel calibre (see text for explanation) |
| PMC1571327__F6 | FGF, Wnt and Tbx3 in epithelial-mesenchymal interactions regulating mammary gland initiation |
| PMC1572165__F3 | Schematic drawing that shows the importance of cell-to-cell and cell-to-matrix-interactions in endothelial cell survival |
| PMC1573858__F1 | AT1 receptor signal transduction pathways that result in transcriptional NA neuromodulation (a) and increased firing rate (b) in neuronal cultures |
| PMC1574111__F3 | Proposed mechanism for FK506-potentiated neurite outgrowth |
| PMC1579207__F1 | Regulation of the ubiquitin ligase SCFMet30 and its connection to cell cycle control |
| PMC1579207__F3 | Cadmium-induced regulation of SCFMet30 |
| PMC1584297__F9 | Cross-talk between the NFKB and the STAT3 pathways |
| PMC15871__F3 | PI3'K signaling modules in mammals and nematodes have implications for cancer |
| PMC1592599__F1 | TNFA signaling pathway leading to apoptosis or proliferation of the cells |
| PMC1592643__F3 | An altered balance of proapoptotic and antiapoptotic molecules in trauma patients' T cells could indicate specifically increased vulnerability to apoptotic depletion |
| PMC1594921__F5 | Presymptomatic and symptomatic infections including the inflammatory cytokines TNFA, IFNG, and ILB |
| PMC1594921__F6 | Immunological regulatory IL-10 and MAP kinase pathways |
| PMC15989__F4 | Hypothetical LYar and LYas cells |
| PMC1599906__F3 | TGFB signaling pathway |
| PMC1599931__F1 | Phosphatidylinositide 3'-OH kinase/Akt/mTOR signaling pathway |
| PMC1600679__F7 | Summary of changes in the Wnt/Beta-catenin pathway in pancreatic adenocarcinoma |
| PMC1601944__F1 | HIF-dependent VHL pathways in oncogenesis |
| PMC1601945__F1 | Model of RNF11 interactions in the TGFB receptor signaling pathway |
| PMC1601946__F1 | E3 ubiquitin ligases regulating the TGFB signaling pathway |
| PMC1602337__F9 | TWEAK-Fn14 signaling system may play a role in stroke pathophysiology |
| PMC1603666__F9 | Erk- and PI3K-Akt-dependent cascades regulating mTOR signaling |
| PMC1609106__F8 | Regulation of insulin pathway phenotypes by AKT-1 and PDK-1 activation |
| PMC1609340__F1 | Outline of the TLR signalling pathway |
| PMC1616944__F1 | Regulation of DNA synthesis by Mec1-checkpoint pathway |
| PMC1617297__F2 | Cell-signaling networks induced by Pichinde virus infection as analyzed using the Ingenuity pathway analysis knowledge base |
| PMC1618798__F2 | Intrinsic apoptotic signaling pathway |
| PMC1618798__F3 | Extrinsic apoptotic signaling pathway |
| PMC1622797__F5 | Proposed molecular model of dietary omega-3 fatty acid interference with IL-1 signaling pathways leading to COX-2 induction in EC |
| PMC1622889__F1 | Anti-apoptosis of families of HSPs |
| PMC1635984__F3 | MRNA expression levels in TGFBeta-treated T84 epithelial cells compared to control cell culture |
| PMC1636619__F8 | Oncogene cooperation in malignant rasV12, scrib-/- tumors |
| PMC1636849__F8 | Schematic summary of the signaling pathway leading to Nanog repression |
| PMC164216__F5 | TLR signaling pathways |
| PMC165090__F8 | Schematic model for the roles of p120 catenin in the signaling pathways leading to growth factor-induced RhoA stimulation and cell migration |
| PMC16561__F6 | The signaling pathway from the upstream protein-tyrosine kinases, Lyn/Syk/Btk, to cytokine gene expression through intermediate signaling proteins, PKCBI/JNK |
| PMC1664647__F1 | Schematic representation of the Fas pathway used in the mechanistic model |
| PMC1664664__F2 | Neurotrophin signalling |
| PMC1664665__F2 | Regulation of the axon cytoskeleton by PI3K signalling |
| PMC1665458__F7 | Proteins differentially regulated in RCC involved in carbohydrate metabolism are shown overlaid on the glycolysis and gluconeogenesis pathway KEGG #00010 diagram |
| PMC1667087__F9 | F igure 9.– |
| PMC167103__F4 | Feed-forward regulation of ABA signaling mediated VP1 and ABI3 |
| PMC1679905__F6 | Signalling routes emanating from the epidermal growth factor receptor (EGFR) |
| PMC1681468__F5 | Ellipsis in drawing association states of proteins using an 'address' |
| PMC1681468__F6 | Combinations of multiple states of complexes |
| PMC1681473__F1b | (B) The bow-tie architecture also exists at the signal transduction level |
| PMC1681476__F1 | An SBGN process diagram (A) and a molecular interaction map (B) of a signaling pathway triggered by ligand binding to EGFR molecules |
| PMC1682009__F1 | Activation of the Akt pathway through binding of a ligand to a receptor, tyrosine kinase |
| PMC1682015__F2 | Example pathway structures based on Z-scores of reactions, which demonstrate the metabolomic response of the selected reactions in the reported case studies, namely, the effect of an altered redox metabolism and aerobic/anaerobic growth |
| PMC1682017__F4 | Effect of increased HER2 expression on phosphorylation sites within the EGFR signaling network |
| PMC1682017__F5 | Effect of HRG stimulation versus EGF stimulation in high HER2-expressing cells |
| PMC1683566__F5 | Integration of gene expression with the proposed mechanistic pathway initiated by comfrey treatment leading to tumorigenesis |
| PMC1698511__F3 | PKR is an intermediary component in TLR signaling |
| PMC1698524__F5 | Model linking HSP70 induction to p33ING1b-induced apoptosis |
| PMC1698527__F10 | Model for the transduction of DNA damage signals to the splicing machinery |
| PMC1698636__F6 | F igure 6.– |
| PMC1698810__F8 | Model for the involvement of JAB1 in TNFA signaling pathway |
| PMC1698952__F4 | Aspects of PRLR signaling as related to mammary gland function |
| PMC1705513__F1 | Inflammatory pathway in psoriasis |
| PMC1705980__F2 | Schematic model of autophagic regulation |
| PMC1716201__F1 | Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737 |
| PMC1716221__F1 | Dominant role for glucose in B cell compensation of insulin resistance |
| PMC1728094__F1 | The receptor for IL-6 consists of the ligand binding component (IL-6R) and the signal-transducing gp130 |
| PMC17313__F1 | Known genes of tryptophan metabolism in E |
| PMC17314__F1 | An integrated view of the biology of Halobacterium NRC-1 |
| PMC1751079__F1 | Inhibitory signals of the Toll-like receptor (TLR)4-induced MyD88-dependent signaling pathway |
| PMC1751493__F2 | In normal prostate epithelial cells (a), TGFB binds to the TBRI and TBRII receptors, activating the SMAD signalling pathway and inducing the transcription of IGFBP-3 and other regulatory genes |
| PMC1754372__F2 | Th1- and Th2-like lymphocytes, and the key regulatory cytokines and their interactions in SS |
| PMC1756898__F1 | Unraveling the Genetics of Human Obesity |
| PMC175791__F10 | Differential regulation of NFAT and SRF by the B cell receptor via a PLCG-Ca2+-dependent pathway |
| PMC1761701__F10 | Proposed model of lacritin mitogenic signaling pathway lacritin signaling suggested by data outlined in the text |
| PMC1763171__F2 | The inflammatory, coagulation, and fibrinolytic pathways are linked at many levels, leading to organ failure and eventually death |
| PMC1764624__F1 | Synthesis and breakdown of proteins by amino acids |
| PMC1766780__F2 | Cytokine signalling and the pathogenesis of severe combined immunodeficiency (SCID) |
| PMC1766919__F1 | Signalling footprints of the TNF/TNF-R superfamily |
| PMC1767116__F3 | Mitochondrial death signalling pathways |
| PMC1768457__F1 | CD14/toll-like receptor 4 (TLR4) intracellular signalling complex |
| PMC1769518__F1 | Complement system consists of about 30 proteins that can be activated by 3 different cascades |
| PMC1769521__F2 | Senescence via tumor suppressor pathways |
| PMC1773546__F3 | The key proinflammatory pathway induced by enteric pathogens results in nuclear factor kappa B (NFKB) mediated transcription of interleukin 8 (IL-8) |
| PMC1774081__F6 | Math1 signalling pathway |
| PMC1774101__F4 | Proposed framework for recruitment of T cells into the gut mucosa by activated CD40L+ platelets |
| PMC1774275__F2 | Intrinsic, or mitochondrial, pathway (after Danial and Korsmeyer) |
| PMC1774275__F3 | Extrinsic, or death receptor, pathway (see text for details) |
| PMC1774275__F4 | The chromosomal instability (CIN) pathway (see text for details) |
| PMC1774275__F5 | Mitogenic signals are transduced by Ras which inhibits the retinoblastoma (Rb) protein allowing E2F and Myc to promote cell cycle progression |
| PMC1774279__F1 | Two major intracellular pathways cause apoptosis |
| PMC1774601__F2 | Death receptor mediated (extrinsic) pathway of apoptosis |
| PMC1774670__F2 | Interaction of JC virus (JCV) T-antigen with key growth regulatory pathways |
| PMC1774670__F6 | P53 pathway |
| PMC1774677__F1 | Diagrammatic indication of the cytokines, transcription factors, and signalling molecules which polarise virgin CD4 cells into T helper cell type I cells |
| PMC1774725__F1 | Tumour necrosis factor related apoptosis inducing ligand (TRAIL) receptor signalling |
| PMC1775040__F2 | Signaling Pathways in Yeast |
| PMC1779520__F3 | Signaling pathways activated by serum and GF treatments |
| PMC1779567__F6 | Functional dissection of signaling modules in human TReg cells |
| PMC1779657__F2 | Recent observations on the regulation of fetal metabolism by glucose |
| PMC1779900__F6 | Some signaling pathways that could mediate long-term changes in cellular plasticity as a function of sexual experience |
| PMC1781062__F1 | CCM2 as a Scaffold for p38 MAPK Activation |
| PMC1781473__F3 | Exploitation of Eukaryotic Ubiquitin Signaling Pathways by Effectors Translocated by Bacterial Type III and Type IV Secretion Systems |
| PMC1781924__F1 | Thy-1-associated signaling pathways |
| PMC1782125__F2 | (a)Signal transduction of TNFRI |
| PMC1782267__F1 | TGFB1-Smad pathway |
| PMC1782267__F2 | TGF-TAK1 pathway |
| PMC1782438__F2 | Role of adaptors in T-cell signalling |
| PMC1782564__F6 | Hypothesized asthma cascade in hapten immune contact sensitized mice, consist of B-1 cell- to immunoglobulin M- (IgM) to complement-driven airway responses |
| PMC1782589__F2 | Signalling cascades of the LPS pathway and reported sites of IL-10 intervention |
| PMC1782589__F3 | IL-10, IL-22 and IL-22 receptor signalling |
| PMC1782796__F7 | Affinity maturation, a turning point between life and death for germinal centre (GC) B cells: a working hypothesis |
| PMC1783068__F1 | Proximal B-cell receptor-mediated signalling pathways |
| PMC1783401__F6 | Integration of Runx1 and the BMP signaling pathway into the SCL transcriptional network |
| PMC1783691__F1 | Differential Roles of Costimulatory Signaling Pathways in Type 1 Diabetes Mellitus |
| PMC1783691__F2 | Differential Roles of Costimulatory Signaling Pathways in Type 1 Diabetes Mellitus |
| PMC1783693__F3 | Involvement of Oxidative Stress and the JNK Pathway in Glucose Toxicity |
| PMC1783813__F3 | Physiology and immunology of the cholinergic antiinflammatory pathway |
| PMC1785270__F6 | A model illustrating the positive and negative regulation of PanK2 activity |
| PMC1785339__F4 | Human and mouse mutations and the cognitive disorders affecting specific NRC/MASC signaling pathways and other postsynaptic proteins |
| PMC1794588__F3 | Small subnetwork identified for the shift from glucose to ethanol as carbon source |
| PMC1796761__F1 | Pathway of double-stranded break repair by homologous recombination and the factors involved |
| PMC1797301__F1 | Flux distribution in D |
| PMC1797633__F1 | Strategies of the different HCV proteins to antagonize IFN therapy |
| PMC1798432__F8 | Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages |
| PMC1800873__F1 | Progression pathway network with w = 0.8, E = 0.8 and the LH algorithm |
| PMC1804347__F4 | Systemic sclerosis: a prototypic multisystem fibrotic disorder |
| PMC1805736__F6 | Pathways for synthesis of adrenal steroids |
| PMC1808970__F3 | AIRE expression is controlled by the lymphotoxin pathway |
| PMC1815248__F5 | Co-option of a developmental pathway by invasive tumors |
| PMC1817693__F4 | MAPK pathway |
| PMC1817784__F2 | Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders |
| PMC1817805__F2 | AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer |
| PMC1819569__F6 | The signalling pathways involved in Pam3Cys-induced degranulation and cytokine/chemokine production in human LAD 2, MLMC and BMMC |
| PMC1820632__F1 | Cytokine-Effects on Glucocorticoid Receptor Function: Relevance to Glucocorticoid Resistance and the Pathophysiology and Treatment of Major Depression |
| PMC1820751__F3 | Ras signaling pathway relays growth signals from activated growth factor receptors to the nucleus |
| PMC1820908__F8 | Schematic diagram of Suc pathway in N2-fixing Anabaena filament cells |
| PMC182218__F2 | Osteoblasts express components necessary for coordinating mineralization of ECM and phosphate handling by the kidney |
| PMC1828071__F3 | Diagrammatic representation of insulin on growth factor signaling through the Ras-Raf, MEK-ERK signaling pathway with downstream effects on gene transcription through ERK translocation |
| PMC1828071__F1a | Intracellular Signaling in Insulin-mediated Regulation of Drug Metabolizing Enzyme Gene and Protein Expression |
| PMC1828071__F2 | Insulin-mediated activation of PI3K signaling pathways |
| PMC1828075__F2 | Diagram showing several factors involved in lens development |
| PMC1828403__F1 | Representation of TLR4-signaling through the MyD88-dependent and MyD88-independent pathways |
| PMC1828869__F2 | Regulation of induction and vesicle nucleation |
| PMC1829400__F5 | TGFB signaling pathway |
| PMC1829419__F4 | Hypothetical regulatory network influencing honeybee pollen foraging behavior modulated by insulin-like signaling and its effects on ovarian development |
| PMC1832150__F1 | CoQ10biosynthetic pathway with eight known biosynthetic enzymes denoted as COQ1-8 |
| PMC1832185__F2 | Dose-dependent entry routes for the EGFR |
| PMC183833__F2 | Canonical Wnt/Beta-catenin pathway |
| PMC1838573__F1 | Mitochondrial pathway through Bcl-2 family members |
| PMC1838942__F1 | gp130 receptor ligands as potential therapeutic targets for obesity |
| PMC1839818__F8 | Model of activation of the 5-ASA-induced checkpoint responses in colon cells |
| PMC1839882__F9 | Schematic illustration of the principal signaling pathways that are affected by sodium arsenite (As) treatment |
| PMC1839891__F1 | Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery |
| PMC1839891__F10 | In this model, the tumor growth process is replaced with the cell cycle model from figure 7 |
| PMC1847380__F14 | Signaling pathways leading to pseudohyphal growth |
| PMC1847380__F15 | Signaling pathways mediating the roles of Rho1 in cell wall assembly and actin organization |
| PMC1847401__F4 | Genes of the insulin/IGF-2 signaling pathway are required for induced stress resistance and induced life extension |
| PMC1847591__F1 | Drugs that regulate hepatic bile acid and other organic solute uptake, synthesis, detoxification and secretion |
| PMC1850660__F1 | Summary of established Beta-catenin pathways |
| PMC1850774__F5 | Convergence of signaling pathways |
| PMC1851054__F6 | SFK-dependent PI3K-ERK2 and phospholipase CG-JNK1 pathways |
| PMC1851929__F8 | Proposed model for the activation of oligodendrocyte apoptosis by MHV infection |
| PMC1851974__F2 | Regulation of cyclin D1 degradation |
| PMC1852210__F1 | Diagram of folate and one-carbon metabolism in mammalian organisms |
| PMC1852238__F1 | Role of the glutathione pathway and ABC-transporter family in drug elimination and defense from ROS-mediated oxidative stress |
| PMC185249__F3 | Sprouty is a rapidly inducible negative regulator of fibroblast growth factor (FGF) pathway signaling |
| PMC185249__F4 | Signal transduction in the Transforming Growth Factor B(TGFB) family pathway is finely regulated at many levels |
| PMC1852551__F4 | Multiple estrogen-regulated steps in the metabolisms of prostaglandin J2 and retinoic acid are implicated in estrogen-dependent growth of human uterine fibroids |
| PMC1852708__F6 | Illustration of key proteins in the Rho GTPase signal-transduction pathway, focusing on the KALRN, CDGAP, and MYLK genes |
| PMC1852742__F2 | Retinoic acid (RA) signaling pathway and CDH candidate genes |
| PMC1852756__F2 | The small nuclear ribonucleoprotein biogenesis pathway |
| PMC1852792__F6 | A hypothetical model for association of four subcomplexes in the FA core complex |
| PMC1852964__F2 | Tyrosine phosphorylation of Beta-catenin, which transiently inactivates the E-cadherin-mediated cell adhesion system and may stimulate the APC-Beta-catenin-Tcf (Wingless-Wnt signaling) pathway, in streak lesions at the invading front of a colorectal cancer |
| PMC1853294__F10 | Cell injury to wound closure, including P2Y activation, intracellular Ca2+ release and EGFR signaling |
| PMC1854955__F7 | Schematic depiction of the molecular mechanism for the progression from HPS to chronic active disease or T-cell lymphoma in EBV-infected T cells |
| PMC1855985__F1 | Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4 |
| PMC1855986__F9 | ATM-Mediated Transcriptional and Developmental Responses to Gamma-rays in Arabidopsis . |
| PMC1856251__F3 | Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine |
| PMC1856765__F3 | Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications |
| PMC1856765__F7 | Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications |
| PMC1856802__F5 | Canonical Wnt signalling pathway and its APC partner in colon cancer development |
| PMC1857250__F2 | Tregs and rethinking cancer immunotherapy |
| PMC1857267__F2 | Altered macrophage differentiation and immune dysfunction in tumor development |
| PMC1857308__F9 | The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones |
| PMC1859939__F5 | Signal transduction pathways involved in Ha-ras-mediated AEG-1 induction |
| PMC1860011__F2 | PPARG as a new therapeutic target in inflammatory bowel diseases |
| PMC1860037__F1 | Role of interleukin 6 in a murine model of Crohn's ileitis: are cytokine/anticytokine strategies the future for IBD therapies? |
| PMC1860592__F2 | Biologic therapies: what and when? |
| PMC1862519__F1 | Intracellular signaling cascades activated by BDNF-stimulated autophosphorylation of TrkB receptors may affect prominent pathways responsible for elevations of intracellular Ca2+ levels in neurons |
| PMC186326__F7 | Model for Fgf18 regulation of long bone growth |
| PMC186370__F1 | Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon |
| PMC1866211__F1 | Hedgehog signalling pathway |
| PMC1866250__F7 | Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance |
| PMC1867237__F3 | ErbB/Ras pathway and Wnt pathway |
| PMC1869626__F2 | Pathway analysis was performed using PathwayStudio software by importing three of the 32-up-regulated genes in our list |
| PMC1869627__F2 | Pathway diagram developed using the Ingenuity Pathways Analysis and Knowledge Base in which all genes changed by more than 1.5 fold were queried |
| PMC1874671__F2 | Genomic organization of the CDKN2A locus and description of involvement of its transcripts (p16INK4a and p14ARF) in the Rb and p53 pathways |
| PMC187486__F8 | Effects of Cdk4 disruption on the pathways controlling senescence and transformation |
| PMC1876599__F3 | Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR |
| PMC1876696__F1 | Pathways for the synthesis of the major phospholipids in S |
| PMC1877048__F1 | Nutritional Route Affects ERK Phosphorylation and Cytokine Production in Hepatic Mononuclear Cells |
| PMC1877091__F15 | PDCD10/MST4 signaling pathway and CCM protein function |
| PMC1878539__F1 | Unchecked thrombin is bad news for troubled arteries |
| PMC1884140__F11 | Schematic representation of the differentially expressed genes and how they are induced upon injection by (A) pristane or (B) phytol |
| PMC1885790__F3 | Diagram illustrating how the Rb and p53 pathways are linked to form a complex tumor suppressor network |
| PMC1885811__F4 | Web-accessible pathway navigator |
| PMC1885837__F6 | Obstructive nephropathy: insights from genetically engineered animals |
| PMC1885990__F1 | Scheme depicting a molecular pathway by which cell-cycle-related molecules promote cell death in neurons in development and disease |
| PMC1890373__F2 | Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands |
| PMC1890551__F1 | Eumelanin synthesis pathway and gene duplications in vertebrates |
| PMC1890551__F4 | Pteridine synthesis pathway and gene duplications in vertebrates |
| PMC1891745__F1 | Diagram illustrating Functional JAK STAT PathwayThis "JAK STAT" pathway appears to be ubiquitous amongst vertebrates |
| PMC1892100__F1 | Image showing the human insulin signaling pathway from BioCarta |
| PMC1892626__F3 | Regulation of hypoxia-inducible factor-1A (HIF-1A) and drug interventions currently in use |
| PMC1894940__F5 | Inhibition of COX-2 modulates multiple functional pathways during acute inflammation and pain |
| PMC1894978__F5 | The secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed |
| PMC1895551__F1 | Prosurvival signaling pathways and their downstream targets |
| PMC1895802__F1 | TGFB signaling pathway and mechanisms of inhibition during leukemogenesis |
| PMC1895816__F2 | Identification of a Bcr-Abl kinase signature |
| PMC1896000__F3 | Diagram of common stress response pathway genes |
| PMC1896004__F4 | Signaling pathways downstream of the Toll/TLRs |
| PMC1899305__F7 | GM-CSF Regulates a PU.1-Dependent Transcriptional Program Determining the Pulmonary Response to LPS |
| PMC1899380__F1 | Late steps in corrin ring biosynthesis in serovar Typhimurium |
| PMC1899901__F6 | A schematic model depicting the role of Artemis in the cellular response to IR |
| PMC1899924__F8 | Signaling pathways activated by mitogenic concentrations of TNFA and roles of furin, MT1-MMP, and MMP2 in the activation of the nSMase in mesenchymal cells |
| PMC1899931__F8 | Theoretical model depicting potential interactions in the intra-S checkpoint signaling pathway |
| PMC1899986__F8 | A model for cyclin E degradation regulated by two E3 ligases |
| PMC1900132__F1 | HCMV MIE promoter/enhancer and its cis-acting elements |
| PMC1904229__F12 | Schematic model of Zfra/WOX1 involvement in TNF signaling |
| PMC1904333__F2 | Hepcidin regulation: ironing out the details |
| PMC1904449__F3 | In silico modeling derived from Pathway Assist software analysis of differential gene expression in JRA neutrophils compared with healthy control subjects |
| PMC1905066__F5 | CRP and mannan-binding lectin (MBL) on complement activation |
| PMC1905373__F7 | Mechanism of complement-dependent haemolysis via the lectin pathway: role of the complement regulatory proteins |
| PMC1905729__F1 | Binding of IL-12 to the IL-12RB1 and B2 chains induces phosphorylation of the kinases Tyk2 and Jak2, which associate with the cytoplasmic tails of the B1 and B2 chains, respectively |
| PMC1905845__S1 | Schematic representation showing the plausible signaling events from uPAR integrin complex |
| PMC1913098__F1 | Sensitivity Analysis of Intracellular Signaling Pathway Kinetics Predicts Targets for Stem Cell Fate Control |
| PMC1913583__F1 | The methionine and folic acid cycles and the metabolic pathway of arsenic |
| PMC1914109__F8 | The p110D →RhoA →PTEN signalling pathway described in the text |
| PMC1919358__F5 | WNT signalling KEGG pathway consisting of three subpathways with the genes on the microarray encircled (A) and expression profiles of genes during porcine myogenesis (B) |
| PMC1924866__F5 | Striped view of multiple time-point comparisons |
| PMC1924866__F6 | Striped view of multiple data types |
| PMC1929113__F6 | Upregulation of cyclins and CDKs in melanoma cells |
| PMC1933158__F6 | A hypothetical model for the dual roles of insulin signaling in human brain |
| PMC1933372__F3 | RAN regulation pathway constituents exhibiting abundance changes, with a figure adapted from the GeneGo MetaCore database |
| PMC1934395__F2 | Combined Effects of Thrombosis Pathway Gene Variants Predict Cardiovascular Events |
| PMC1934514__F2 | Mechanisms of Action of GLP-1 in the Pancreas |
| PMC1934514__F4 | Schema outlining the signaling mechanisms reported to be involved in GLP-1R-induced differentiation/neogenesis of pancreatic precursor cells, proliferation and in the prevention of apoptosis |
| PMC1934518__F2 | Ligands identified for EpCAM and possible functions related to them |
| PMC1936363__F1 | Epidermal growth factor receptor pathway |
| PMC1937523__F3 | Comparison between the gene expression profiles and predicted substrate uptake rates |
| PMC1937548__F4 | Comparison of nonsynonymous substitution rates among members of RB and p53 signaling pathways |
| PMC193774__F3 | Metabolic map showing relative expression ratios (intensity of TF5015 versus that of W3110) of transcript levels in the central metabolic pathway (A) and the threonine biosynthetic pathway (B) |
| PMC19384__F10 | A model of thymic differentiation |
| PMC193872__F3 | Conserved longevity-regulatory pathways in S |
| PMC1939900__F6 | Different signaling pathway mediated by A3(IV)NC1 |
| PMC1940051__F2 | TGFB signaling pathway |
| PMC1948012__F10 | Action for AICAR in human leukemia ALL cells |
| PMC1949901__F1 | Current understanding of the pathways of fatty acid synthesis which are known to occur within the Brassicaceae |
| PMC1951379__F6 | IFN signaling during the clinical evolution of SARS |
| PMC1951533__F14 | Proline-Rich Tyrosine Kinase 2 Mediates Gonadotropin-Releasing Hormone Signaling |
| PMC1951751__F10 | A model for the regulation of AJC disassembly in calcium-depleted cells |
| PMC1951772__F8 | PI3K activation by eIF2A kinases |
| PMC1952166__F1 | Signaling cascades required for TCR-mediated integrin activation |
| PMC1952230__F1 | Regulation of CXCR4 Signaling |
| PMC1952634__F4 | Evolving biology and treatment of prostate cancer |
| PMC1952636__F9 | Beta-Arrestin-mediated B1-adrenergic receptor transactivation of the EGFR confers cardioprotection |
| PMC1952644__F1 | Alternative signaling: cardiomyocyte B1-adrenergic receptors signal through EGFRs |
| PMC1952649__F2 | Two tales concerning skeletal muscle. |
| PMC1955177__F3 | Cell death in the cardiovascular system |
| PMC1955758__F2 | How both apoptotic death and immunity may be triggered by dsRNA |
| PMC1958996__F2 | Transcriptional control of adipocyte formation |
| PMC1959234__F1 | Schematic model for the "error-free" BRCA double strand break repair pathway Brief overview of components within the BRCA pathway used here as a working model that was tested here |
| PMC195990__F5 | A model of Hip1's role in lung branching morphogenesis |
| PMC196255__F1a | Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway |
| PMC1963413__F1 | Oval of iNOS-inducing signaling pathways |
| PMC1963416__F1 | Signaling mechanisms for the activation of HAT and HDAC |
| PMC1964512__F3 | Type I IFN innate immune response to adenovirus-mediated IFNG gene transfer contributes to the regression of cutaneous lymphomas |
| PMC1964754__F6 | Furin in development, homeostasis and disease |
| PMC1964795__F5 | INHIBITION OF MAPK AND STIMULATION OF AKT KINASE SIGNALING PATHWAYS: TWO APPROACHES WITH THERAPEUTIC POTENTIAL IN THE TREATMENT OF NEURODEGENERATIVE DISEASE |
| PMC1965265__F6 | A schematic representation of differential testosterone action on morphoregulatory gene expression in the rat VP and LP lobes |
| PMC1971124__F4 | BDCA2/FcERIG Complex Signals through a Novel BCR-Like Pathway in Human Plasmacytoid Dendritic Cells. |
| PMC1974879__F1 | Transcriptional profile of Rous Sarcoma Virus transformed chicken embryo fibroblasts reveals new signaling targets of viral-src |
| PMC1974887__F1 | Endogenous Synthesis of Coenzyme Q in Eukaryotes |
| PMC1975829__F1 | Viral infections: beneficial role of eosinophils |
| PMC1976331__F1 | Linking Metabolic QTLs with Network and cis-eQTLs Controlling Biosynthetic Pathways |
| PMC1978064__F4 | MiR-103/107 and PANKs may constitute coordinated transcription units with synergistic cellular effects concerning cellular acetyl-CoA levels and other metabolic pathway elements |
| PMC198547__F8 | Leptin action on the TRH neuron |
| PMC1986651__F1 | Regulation of cell proliferation and cell death by PKCE |
| PMC1986780__F2 | Role of XIAP in the extrinsic and intrinsic cell death signaling pathways |
| PMC1988867__F7 | Ingenuity pathway analysis showing regulatory relationships among differentially expressed transcripts |
| PMC1991338__F1 | ZIP1 expression and zinc accumulation in the pathway and bioenergetics of citrate production and citrate oxidation in normal versus malignant prostate cells |
| PMC199181__F1 | Biochemistry of NFKB activation |
| PMC199181__F2 | Proposed mechanisms of NFKB activation in HIV-1-infected cells |
| PMC199181__F3 | The NFKB pathway by viruses |
| PMC1992444__F3 | Interaction map of the Notch signaling pathway |
| PMC1992519__F2 | Signaling on the endocytic pathway |
| PMC1993849__F7 | Ischemic/hypoxic effects on cardiac myocytes and stem cells |
| PMC1993861__F7 | Model summarizing the hypothesis on narciclasine-mediated apoptosis |
| PMC1993906__F16 | Adenylyl cyclases are targets of multiple regulatory signaling pathways and respond differently, depending on which group they belong to |
| PMC1994616__F1 | New molecularly targeted therapies for lung cancer |
| PMC1994616__F2 | New molecularly targeted therapies for lung cancer |
| PMC1995566__F7 | Oxidative stress initiates a cascade of reactions leading to cell death via one or more sequences of molecular events |
| PMC1995599__F2 | MOLECULAR AND CELLULAR MECHANISMS OF THE ANABOLIC EFFECT OF INTERMITTENT PTH |
| PMC1998879__F2 | Molecular pathway associated with neuronal migration |
| PMC1998884__F1 | Pathways involved in GSIS |
| PMC1999497__F2 | Flow diagram of the P53/apoptosis pathway |
| PMC2000337__F7 | An Essential Role for 14-3-3 Proteins in Brassinosteroid Signal Transduction in Arabidopsis |
| PMC2000831__F3 | Proliferation induced by androgen independent pathways |
| PMC2002564__F1 | Arterial-venous specification in the developing embryo |
| PMC2002614__F9 | N-Acylethanolamine Metabolism Interacts with Abscisic Acid Signaling in Arabidopsis thaliana Seedlings |
| PMC20092__F5 | A model for the v-Crk-mediated signaling pathway |
| PMC2013735__F4 | GenMapp pathway showing the impact of 1 week of STZ-DM on transcription in pathways related to cytokines and the inflammatory response |
| PMC2013861__F4 | Signalling pathways activated by the RXFPs |
| PMC2014644__F2 | PGE2-EP receptor signaling pathways |
| PMC2039930__F7 | Signal transduction pathways involved in Ha-ras-mediated AEG-1 induction |
| PMC2040031__F1 | INTERLINKING INTERLEUKIN-7 |
| PMC2040891__F5 | UVB acts at both the switch and the switched pathway to trigger UV-induced apoptosis |
| PMC2042021__F6 | Contrasting Infection Strategies in Generalist and Specialist Wasp Parasitoids of Drosophila melanogaster |
| PMC2042025__F3 | Notch pathway is a frequent target of insertion |
| PMC2042178__F2 | PTEN/PI3K/mTOR/STAT3 signaling involved in breast cancer stem-like cell survival and proliferation |
| PMC2043390__F9 | Biphasic expression and up-regulation of HWP1 at the bud-hypha transition |
| PMC2043401__F1 | Schematic outline of fatty acid synthesis in apicomplexans |
| PMC20438__F5 | Schematic diagram of possible Rad6-mediated metabolic pathways |
| PMC20445__F6 | Schematic diagram showing steps in the signaling pathway by which P |
| PMC2045534__F6 | Schematic model of the role played by GADD34 and the mTOR pathway in the suppression of viral replication |
| PMC2045624__F1 | OX40 signaling directly triggers the antitumor effects of NKT cells |
| PMC2048738__F1 | Reactions of the Calvin cycle, starch synthesis, photosynthetic carbon oxygenation pathway, triose-P export, and Suc synthesis represented in the model (Supplemental Appendix S1, A and B) |
| PMC2063509__F1 | AUTOPHAGY: HIGHLIGHTING A NOVEL PLAYER IN THE AUTOIMMUNITY SCENARIO |
| PMC2063513__F6 | Gene Expression in Human Hippocampus from Cocaine Abusers Identifies Genes which Regulate Extracellular Matrix Remodeling |
| PMC2063536__F7 | ES cell-based model describing the ontogeny of NSCs |
| PMC2063755__F1 | Signaling events during EMT |
| PMC2063819__F7 | The newly identified NT3-activated signaling pathway |
| PMC2064427__F10 | Schematic diagram illustrating the signaling mechanisms that control the bidirectional responses of the growth cone to BMP7 gradients |
| PMC2064670__F5 | Model integrating calcium mobilization into the Fas signaling pathway |
| PMC2064840__F9 | Divergent TGFB signaling pathways induce transcriptional regulation through Smads and translational regulation through the mTORC1 pathway |
| PMC2066195__F10 | IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice |
| PMC206993__F9 | SPARC-mediated regulation of and coupling to the TGFB signaling system |
| PMC2071927__F2 | TUNING IMMUNE TOLERANCE WITH VASOACTIVE INTESTINAL PEPTIDE: A NEW THERAPEUTIC APPROACH FOR IMMUNE DISORDERS |
| PMC2075035__F2 | Scheme of the Leloir pathway |
| PMC2075035__F4 | Scheme of the LNB/GNB pathway in B |
| PMC2075101__F1 | 5-HT2A receptor agonists cause activation of GAq/11 proteins which in turn activate the second messenger enzyme PLC |
| PMC2075270__F1 | Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle |
| PMC2077852__F3 | Dmp1 links the Rb and p53 pathways |
| PMC2077853__F9 | Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation |
| PMC2078333__F1 | Summary of known actions of activated ras-p21 in cells, beginning (top, left) when a growth factor binds to its cell receptor |
| PMC2080843__F5 | Simulation of the Apoptosis pathway under FasL stimulation (black starred line), bacterial only (red circled line) and both (blue triangled line) |
| PMC2080907__F8 | Myc and Ca2+signaling events downstream of the pre-BCR/BCR |
| PMC2082051__F5 | Networks of pathways unique in the HIV-1 regulated mPBMCs |
| PMC2082128__F7 | Biosynthetic pathway for the ganglio-series of glycosphingolipids |
| PMC2083698__F6 | Promiscuous Mutations Activate the Non-Canonical NF-kB Pathway in Multiple Myeloma |
| PMC208733__F1 | Regulation of the Foxa and Foxo transcription factors through PI3-kinase signaling |
| PMC2089068__F3 | Relative transcript levels for genes from carbon central metabolism for PB12 (first value) and PB13 (second value), as compared to JM101 |
| PMC2089068__F4 | Relative transcript levels for genes from carbon central metabolism for L-Phe overproducing strains |
| PMC209288__F1 | The biosynthetic pathway for the fibrillar collagens expressed in skin, identifying steps that are affected in different forms of EDS |
| PMC2093951__F9 | NOVEL VIP SIGNALING PATHWAY IN T CELLS cAMP→Protein Tyrosine Phosphatase (SHP-2?)→JAK2/STAT4→Th1 differentiation |
| PMC209410__F1 | The EXT proteins and HS biosynthesis |
| PMC209410__F2 | A working model of mammalian bone development |
| PMC2094118__F1 | The HIF1 pathway in normoxia (A) and hypoxia (B) |
| PMC2094129__F2 | Respective balance between Gi- and Gs-dependent signalling pathways and their roles in the modification of FcARI-mediated mast cell degranulation |
| PMC209413__F1 | The TGF-&bgr;/Smad pathway and its interrelationship with mediators of inflammatory signals |
| PMC209477__F2 | gp130 cytokine family pathways on anterior pituitary cells |
| PMC209479__F1 | Corticotroph SOCS-3 as an intracellular suppressor of cytokine signaling |
| PMC209479__F2 | Inhibitory effects of SOCS-3 and SHP-1 on LIF-mediated gene expression |
| PMC2096753__F1 | Summary of purinergic pathways involved in microglial response |
| PMC2097959__F2 | INTEGRATING RADIOTHERAPY WITH EGFR ANTAGONISTS AND OTHER MOLECULAR THERAPEUTICS FOR THE TREATMENT OF HEAD AND NECK CANCER |
| PMC2099483__F1 | Circadian oscillation in leptin signaling pathway in mouse brown fat |
| PMC2099624__F9 | Schematic model of Nrf2 regulation by Keap1 |
| PMC2100073__F6 | Filamentation signaling pathway recovered completely |
| PMC2100342__F3 | Activation of NFKB via the classical and the alternative pathway |
| PMC2100400__F2 | Innate and Adaptive Immune Response to Apoptotic Cells |
| PMC2100434__F2 | Growth hormone-mediated JAK/STAT signal transduction |
| PMC2106361__F1 | Current model of the Fanconi anemia pathway |
| PMC2106369__F1 | Schematic overview of the RANK-NFKB signalling pathway |
| PMC2118167__F7 | Proposed model for the intersection of innate and adaptive immunity during polysaccharide-induced abscess formation in the peritoneal cavity |
| PMC2118421__F7 | Proposed model of RasGRP1 in FcɛRI-mediated signaling |
| PMC2121320__F2 | MTA family of coregulators in nuclear receptor biology and pathology |
| PMC2128044__F12 | Hierarchical representation of the JAK-STAT pathway with SOCS1 subsystem as a coordinator |
| PMC2131730__F4 | LPS signals the TLR4 pathway on an APC (i.e., monocyte or dendritic cell) |
| PMC2133163__F6 | Anchorage-dependent cell growth |
| PMC2134838__F2 | ALTERNATE ROUTES FOR DRUG DELIVERY TO THE CELL INTERIOR |
| PMC2134905__F2 | The p53 pathway and IGFBP3 |
| PMC2136409__F7 | Genetic and epigenetic mechanisms of gene regulation during lens development |
| PMC2136409__F8a | Genetic and epigenetic mechanisms of gene regulation during lens development |
| PMC213796__F7 | EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer |
| PMC2140184__F2 | The hypoxia-inducible factor (HIF)-1 pathway |
| PMC2147077__F4 | A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety. |
| PMC2147675__F1 | Antimalarial therapy prevents Myc-induced lymphoma |
| PMC2148057__F5 | GenMAPP view of energy production pathway in MCF-7 and ZR75-1 cells |
| PMC2148057__F6 | Sugar metabolism pathways in MCF-7 and ZR75-1 cells profiled by GenMAPP |
| PMC2148057__F8 | Proteosomal degradation pathway |
| PMC2148066__F6 | GenMAPP pathway showing changes in expression of the transcription factor PPARA and fatty-acid degrading enzymes upon fasting |
| PMC2149843__F1 | A pro-adhesive PPARGamma-mediated chemokine receptor switch, CCR2→CX3CR1, in atherosclerosis |
| PMC2150790__F9 | The signaling pathways activated by N |
| PMC2151350__F2 | Model for renal pathology in Dent's disease (due to a loss of ClC-5) The small peptide PTH (parathyroid hormone) and various forms of vitamin D (VitD; bound to their binding protein) pass the glomerular filter into the early proximal tubule (A) |
| PMC2151384__F2 | CON and NR samples; black/white boxes denote genes not detected on the human genechip with baboon RNA generated probe |
| PMC2151841__F4 | Signal transduction pathway in the UPR |
| PMC2151969__F4 | Genes up-regulated and down-regulated by FGF-2 in IGF-I signaling pathway |
| PMC2151969__F5 | Genes up-regulated and down-regulated by FGF-2 in TGFB signaling pathway |
| PMC2153436__F4 | Immune Response and Cell Cycle Networks |
| PMC2153443__F8 | TGFB SIGNALING BY PROINFLAMMATORY CYTOKINES IN ARTICULAR CHONDROCYTES |
| PMC2168342__F7 | Matrilysin and stromelysin-2 differentially control apoptotic transcriptional response |
| PMC2168724__F1 | Coenzyme B12 biosynthesis in serovar Typhimurium |
| PMC2168916__F7 | Regulation of the AHR-XRE pathway by NRF2 |
| PMC2169053__F6 | Model for SCF-mediated regulation of hFBH1 and Srs2 turnover in response to DNA damage |
| PMC2169177__F10 | Schematic view of Ras- and calcineurin-dependent pathways in T cells |
| PMC2171390__F7 | Calcium-independent microtubule-dependent pathway is required for FcɛRI-mediated degranulation in mast cells |
| PMC2171731__F9 | Invadopodium formation |
| PMC2172299__F8 | A hypothetical model showing the roles of Fak and paxillin in motile HeLa cells |
| PMC2172900__F9 | A model of how the Tor1/2 and Lst8 proteins affect amino acid biosynthesis and Gap1p sorting |
| PMC2173020__F1 | Cross-talk between growth factors and integrins in endothelial cells |
| PMC2173577__F9 | Proposed model for the roles of Sos-1 in the signaling pathway leading to activation of Rac |
| PMC2173691__F7 | Mechanisms of E-cadherin regulation in sparse and dense cultures of colon cancer cells |
| PMC2173816__F3 | Down-regulation of the inflammatory response |
| PMC2173906__F7 | Hypothetical scheme of the mechanism by which Dkk1 promotes osteolytic lesions in vivo |
| PMC2174844__F8 | The FN-dependent matrix survival pathway activated in primary RSF when serum is absent |
| PMC2174913__F2 | Checkpoints activated upon rereplication |
| PMC2174972__F7 | The Viral Oncoprotein LMP1 Exploits TRADD for Signaling by Masking Its Apoptotic Activity |
| PMC2175514__F5 | Transcription regulatory network indicates utilization of various transcription factors following activation of TLR7 |
| PMC2175514__F9 | Protein regulatory network indicates importance of ISGylation pathway in TLR7-mediated activation of pDC |
| PMC2176131__F7 | Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor-B Signaling |
| PMC2180215__F1 | Comparison of the protein kinase/phosphatase signaling pathways in flies, worms, and humans (see text for description) |
| PMC2180420__F9 | Co-coculture system reveals the involvement of intercellular pathways as mediators of the lutropin receptor (LHR)-stimulated ERK1/2 phosphorylation in Leydig cells |
| PMC2192627__F1 | Signaling mechanisms involved in lifespan regulation and the cellular response to genotoxic stress |
| PMC2193446__F7 | The hypothesized biochemical pathway responsible for the hyperproliferative phenotype of Nf1 +/- mast cells in response to SCF |
| PMC2193492__F1 | Pathways initiating transcription from pIV of the CIITA gene |
| PMC2194118__F6 | Molecular dissection of the signaling cascade underlying BCR-controlled integrin A4B1-mediated adhesion |
| PMC2194763__F5 | Cell cycle pathway diagram obtained from GenMAPP (Gene Map Annotator and Pathway Profiler, Gladstone Institutes, University of San Francisco, San Francisco, CA [38] |
| PMC219483__F1 | Biochemical pathways of TSH and folate metabolism in Leishmania |
| PMC2195651__F1 | Fas (death receptor) signaling pathway and its inhibition |
| PMC2195865__F1 | Extrinsic and intrinsic cell death signaling pathways |
| PMC2195911__F10 | A molecular mechanism whereby cAMP inhibits T cell function |
| PMC2196458__F7 | Fas-signaling pathways in relation to the cytoskeletal networks, the Golgi-sorting compartment, and the surface membrane |
| PMC2198843__F1 | Adhesion regulation of nucleocytoplasmic trafficking of signaling molecules |
| PMC2202913__F1 | Control of Food Intake by the Hypothalamic Leptin-Melanocortin PathwayThe hypothalamus receives and integrates neural, metabolic, and hormonal signals to regulate energy homeostasis |
| PMC2203613__F10 | Functional interacteome of all parietal cortex proteins |
| PMC2206000__F2 | Molecules and pathways implicated in sulfur mustard (SM)-induced apoptosis |
| PMC2206598__F4 | Regulatory networks sensitive to tyrosine kinase inhibitors in H3255 and MKN45 cells revealed by PhosphpScan-SILAC study |
| PMC2211462__F3 | Tyrosinase (TYR) and Tyrosinase-related protein 1 (TYRP1) processing and the melanin biosynthetic pathway in the melanocyte and in the melanosome, respectively |
| PMC2211634__F3 | Models for the dual roles of KLF4 and KLF5 in tumor suppression and oncogenesis |
| PMC2212135__F6 | Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2 |
| PMC2212359__F5 | HToll and TNFR-1 signaling pathways |
| PMC2212850__F2 | Major signaling pathways for type I IFN gene transcription |
| PMC2213034__F8 | Our model for the mechanism of anti-CD63 inhibition |
| PMC2213056__F1 | AID-initiated SHM pathways |
| PMC2213208__F1 | Activation of the vagus nerve leads to the release of acetylcholine (Ach) that binds to Alpha-7 nicotinic receptors (A7 nAChR) on cytokine producing cells |
| PMC2213224__F8 | Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion |
| PMC2214701__F3 | Building bone to reverse osteoporosis and repair fractures |
| PMC2215765__F1 | Schematic overview of the LPS TLR4 signaling pathway |
| PMC2217489__F4 | F igure 4 |
| PMC2219351__F1 | Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients |
| PMC2219551__F7 | Signaling Pathway Involved in Neutrophil Elastase-Stimulated MUC1 Transcription |
| PMC2220082__F2 | Rosilitazone stimulates NSCLC proliferation by affecting the Akt/mTOR pathway through PPARGamma-dependent and PPARGamma-independent mechanisms |
| PMC2223843__F2 | TLR3 signaling pathways |
| PMC2224366__F9 | Innate immune modulation of CTL response to LCMV through MyD88 signaling |
| PMC2224586__F3 | HCMV regulates the expression of multiple components of the NFKB signaling pathway (see Table and Table S1 in the supplemental material for abbreviations) |
| PMC2224766__F3 | Proposed metabolic pathway for PSI-6130 |
| PMC2225459__F2 | Schema illustrating the effects of (a) metformin- or AICAR-induced AMPK activation, (b)adiponectin, and (c) TZDs or PPAR alpha ligands on the rat granulosa cell steroidogenesis |
| PMC2225983__F3 | PI3K-AKT pathway is transcriptionally regulated throughout the lactation cycle |
| PMC2228275__F3 | A signaling network links genes regulated by GCs in CEM cells |
| PMC2230095__F8 | Proposed model for the cAMP-dependent signaling events involved in the neurotrophic actions of PACAP-38 on SH-SY5Y cells |
| PMC2230579__F10 | Left, the mechanism, described by , for the proapoptotic function of TSP1 or 2 |
| PMC2233667__F6 | Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens |
| PMC2233890__F4 | Multiple ERK scaffold regulate growth factor and adhesion signaling |
| PMC2234347__F2 | CNX/CRT cycle |
| PMC2234385__F10 | Model of TLR ligand activation of Kupffer cell-NK cell cross talk in co-culture |
| PMC2234434__F3 | Genes involved in apoptotic pathways were altered in type II cells isolated from Stat3ÃŽâ€/Άmice |
| PMC2234581__F8 | Working Model for Multifunctional Proteins PHB and REAPHB and REA are able to interact with each other to form hetero-oligomers |
| PMC2235195__F1 | RA synthesis pathway |
| PMC2235216__F1 | Arsenic-induced acquired androgen independence |
| PMC22365__F5 | Evolutionary conservation of the DNA damage and the replication checkpoints |
| PMC2238720__F2 | Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions |
| PMC2238789__F2 | a Cell processes predicted to be influenced by the top up-regulated priority genes (164 genes showing a differential expression >1 log2) based on in silico analysis employing the ResNet database (PathwayStudio 5.0, Ariadne) |
| PMC2238789__F3 | Hypothetical 'super pathway' not stratified for cell type illustrating known direct interactions between the 892 PD priority genes (regulation, expression and promoter binding only) |
| PMC2238789__F4 | Neuronal pathway containing proteins found in Lewy bodies [] |
| PMC2238789__F5 | Interactions of known PD genes (marked yellow) with the priority genes of this study |
| PMC2238877__F4 | PharmGKB Irinotecan Pathway |
| PMC2241839__F3 | Cholesterol biosynthesis pathway |
| PMC2242658__F8 | Wingless and integration site growth factor (WNT)-induced epidermal growth factor receptor (EGFR) transactivation |
| PMC2242712__F1 | Phenolic lipid synthesis in A |
| PMC2242750__F1 | Schematic representation of GADS-related signaling in T cells |
| PMC2245955__F5 | Gene expression changes observed in Sema3A signaling pathway |
| PMC2246131__F7 | Schematic diagram showing the possible effects of the reelin pathway in protection from CM |
| PMC2246264__F9 | Proposed mechanism for MnSOD-mediated mitochondria to nucleus signaling and crosstalk with the IIS pathway |
| PMC2247392__F2 | Growth factors trigger local and long distance signalling |
| PMC2248159__F2 | A part of the yeast cell cycle pathway available from KEGG [26] |
| PMC2253531__F5 | Induction of immune response to Wolbachia infection in S2 cells |
| PMC2254474__F1 | P2Y receptor-mediated signalling cascades in C6 cells |
| PMC2254485__F5 | Tumour growth and metastasis: Role of NPP2-catalyzed reactions |
| PMC2254585__F5 | In silico knockout of PLCG1 in the HGF stimulated signalling network |
| PMC2254980__F3 | Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice |
| PMC2254980__F4 | Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice |
| PMC2257939__F2 | Bimodal genes highlighted in KEGG ECM-receptor interaction diagram |
| PMC2258259__F1 | Metabolic pathways involved in pyrimidine metabolism |
| PMC2258669__F1 | Genomic and functional context of glycerate kinase enzymes in bacteria |
| PMC2258669__F3 | Enzymatic reactions and assays |
| PMC2258989__F6 | Schematic presentation of the signaling pathway induced by HCV core protein for insulin resistance in human hepatocytes |
| PMC2259254__F2 | Balance between muscle hypertrophy and atrophy depends on whether protein synthesis is more active than degradation or vice versa |
| PMC2259386__F1 | Prototypical myelin-derived neurite growth inhibitors, their receptors and intracellular signaling pathway |
| PMC2259464__F2 | TGFB signaling pathway |
| PMC2259464__F3 | The Hedgehog signaling pathway |
| PMC2262896__F4 | TCR signaling pathway |
| PMC2262896__F6 | Interferon signaling |
| PMC2263022__F6 | Superposition of 'omics' data on maps |
| PMC2265304__F1 | Idiopathic Pulmonary Fibrosis: Aberrant Recapitulation of Developmental Programs? |
| PMC2266095__F2 | Schematic presentation of the NFKB signaling network in radiation-induced adaptive radioresistance |
| PMC22667__F1 | Pheromone response pathway in yeast and summary of epistatic interactions with STE4 and STE11 |
| PMC2266794__F4 | Integrative Genome-Wide Expression Analysis Bears Evidence of Estrogen Receptor-Independent Transcription in Heregulin-Stimulated MCF-7 Cells |
| PMC2267714__F3 | Gene expression changes detected in selected pathways in M group |
| PMC2267731__F2 | BL module: A network visualization of the top 25 scoring genes in BL |
| PMC2268054__F1 | Role of glycoprotein 130 (gp130) downstream signalling in the heart |
| PMC2268054__F2 | Mutations in the glycoprotein 130 (gp130) receptor lead to an imbalance in downstream signalling pathways |
| PMC2268064__F2 | Signalling pathways leading to the phosphorylation and inhibition of glycogen synthase kinase 3 (GSK3) |
| PMC2268661__F2 | The diagram of GSH redox cycle |
| PMC2268699__F1 | p38 MAPK canonical signalling pathway |
| PMC2268699__F2 | FGF canonical signalling pathway |
| PMC2268740__F1 | Neuroarchitecture of Aminergic Systems in the Larval Ventral Ganglion of Drosophila melanogaster |
| PMC2268796__F6 | The signaling pathways regulating cell cycle and differentiation in tumor cells in response to shear stress |
| PMC2268956__F3 | The major pathways leading to apoptosis |
| PMC2268988__F3 | Life and death decisions by the E2F transcription factors |
| PMC2269037__F3 | PI3K/AKT signaling pathway activated by 3Alpha-diol |
| PMC2270353__F4 | NPTX2 pathway obtained by means of the Resnet 5.0 eukaryotic database of molecular interactions (Ariadne) overlayed with microarray expression values |
| PMC2270852__F5 | Schematic of signaling pathways in PDAC |
| PMC2274947__F6 | Acrolein-Activated Matrix Metalloproteinase 9 Contributes to Persistent Mucin Production |
| PMC22753__F6 | A signal transduction pathway leading to the phosphorylation and activation of mTOR in response to insulin |
| PMC2275788__F2 | Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast |
| PMC2276341__F3 | Network analysis of target genes |
| PMC2276649__F8 | GSK-3B Targets Cdc25A for Ubiquitin-Mediated Proteolysis and GSK-3B Inactivation Correlates with Cdc25A Overproduction in Human Cancers |
| PMC2276852__F7 | Schematic representation of the proposed events triggered by exposure to replication inhibitors such as APH |
| PMC2276871__F1 | Steroid receptor expression in postnatal day 5-10 developing prostates from oil-treated control rats (A) and neonatally estrogenized rats (B) |
| PMC2277216__F1 | Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history |
| PMC2277398__F1 | MAP kinase pathway analysis of the meta-modes |
| PMC2277413__F4 | Gene Network A |
| PMC2277413__F5 | Gene Network B |
| PMC2277498__F3 | Pharmokinetic Limitations of Antioxidant Treatment for COPD |
| PMC2278039__F2 | FIP200, a key signaling node to coordinately regulate various cellular processes |
| PMC2278091__F1 | F igure 1.– |
| PMC2279152__F1 | Apoptosis signalling pathways |
| PMC2279300__F6 | Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors |
| PMC2287275__F2 | Mesenchymal stem cell dysfunction in HGPS |
| PMC2288663__F6 | Nucleotide excision repair pathway |
| PMC2290973__F2 | Pathway Studio diagram of common regulators of differentially expressed genes |
| PMC2291030__F3 | EGF signaling pathway generated by the Ingenuity Pathway Analysis (IPA) software |
| PMC2291295__F1 | Keratinocyte Apoptosis in Epidermal Development and Disease |
| PMC2291295__F2 | Keratinocyte Apoptosis in Epidermal Development and Disease |
| PMC2292467__F6 | DNA replication and damage checkpoint regulation |
| PMC2292640__F1 | SARS CORONAVIRUS AND INNATE IMMUNITY |
| PMC2293084__F8 | PARP-1 in NFAT signaling pathway |
| PMC2293256__F4 | Reannotation processes |
| PMC230332__F7 | Extracellular and intracellular antagonism of BMP signaling by myostatin and TGFB |
| PMC2311275__F4 | Following biological functions (central carbon pathway, redox and respiration coordination, phosphate starvation, nitrogen gestion, carbohydrates, nucleotide and amino acids metabolism, ribosome activity) |
| PMC2311292__F2 | Pathway representation of all the tryptophan related genes analyzed |
| PMC2312359__F4 | Composite list of expressed genes and enriched transcription factors implicates specific regulatory networks |
| PMC2315681__F8 | Leptin's roles in the endocardial cushion |
| PMC2315691__F1 | Complement system and complement regulatory proteins (CRegs) |
| PMC2322867__F2 | Rapid Signaling Mechanisms of Estrogens in the Developing Cerebellum |
| PMC2323197__F1 | Immunosuppression in islet transplantation |
| PMC2323406__F4 | Stimulus Design for Model Selection and Validation in Cell Signaling |
| PMC2324124__F1 | The core Notch signalling pathway |
| PMC2329845__F2 | IPA of the genes encompassed by the conserved 166 signatures and belonging to the Wnt signal transduction pathway |
| PMC2330230__F9 | Candidate interactors and their putative postion in the Frizzled signaling pathway |
| PMC2342468__F1 | Cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice |
| PMC2346559__F1 | An Allosteric Mechanism for Switching between Parallel Tracks in Mammalian Sulfur Metabolism |
| PMC2349095__F2 | Triggering and amplification of the Wnt/Beta-catenin pathway in osteocytes in response to load |
| PMC2358943__F1 | Metabolism of PtdIns(4,5)P2 by PLCG and PI3K |
| PMC2358953__F2 | Network diagram showing the checkpoint response to uncapped telomeres |
| PMC2360352__F1 | Schematic depicting the central role of HER3 in mediating PI3K/Akt signalling downstream of the HER family |
| PMC2360544__F2 | Novel therapeutic targets and proposed mechanisms of androgen resistance (text in red) in hormone refractory prostate cancer |
| PMC2360674__F8 | Schematic of porphyrin-synthetic pathway to illustrate potential control points for increased PpIX accumulation |
| PMC2361115__F1 | Cytoplasmic/traditional and nuclear modes of the EGFR signalling pathway |
| PMC2361211__F2 | Overview of signal transduction pathways and role of selective inhibitors |
| PMC2361340__F5 | Differential targets of copy number-induced expression changes in key biochemical pathways between SCLC and NSCLC |
| PMC2364238__F1 | SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer. |
| PMC2366099__F1 | Folate and one-carbon metabolic pathway |
| PMC2367054__F5 | Uncovering Genes with Divergent mRNA-Protein Dynamics in Streptomyces coelicolor |
| PMC2373983__F1 | Human T-Cell Leukemia Virus Type 1 Blunts Signaling by Interferon Alpha |
| PMC2374452__F5 | Molecular pathways of rheumatoid arthritis-related cartilage destruction as reflected by the in vitro model |
| PMC2374589__F1 | Programmed cell death can be executed via extrinsic and intrinsic pathways depending on the stimulus leading to apoptosis |
| PMC2374711__F5 | Proposed model of APL pathogenesis induced by PML-RARA |
| PMC2374962__F2 | Regulation of glycolysis and fatty acid synthesis |
| PMC2374972__F8 | A proposed mechanism for p,p'-DDE-induced proliferation of hormone-dependent cells |
| PMC2375563__F1 | Muscle growth: no IGFs, ands, or buts |
| PMC2375600__F2 | From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy |
| PMC2376243__F8 | Schematic mechanism of AB oligomer-mediated aberrant PAK activation and translocation in Alzheimer disease pathogenesis |
| PMC2376838__F8 | LRG-Accelerated Differentiation Defines Unique G-CSFR Signaling Pathways Downstream of PU.1 and C/EBPE That Modulate Neutrophil Activation |
| PMC2377014__F10 | BDNF enhancement of glutamate-induced phase shifting in the SCN, and potential locations in the signaling pathway where ethanol could inhibit this process |
| PMC2377356__F2 | Involvement of IRAK-2, M, and 4 in the differential regulation of NFkB pathway |
| PMC2383880__F1 | Manual layout of Type II interferon signalling (IFNG) taken from the integrated pathway diagram (Figure 2) |
| PMC2383880__F7 | A logic-based diagram of signalling pathways central to macrophage activation. |
| PMC2383925__F9 | MiRNA model for the molecular pathogenesis of recurrent ovarian cancer |
| PMC2384123__F8 | Possible model for CCL5-mediated mRNA translation in CD4+ T cells |
| PMC2386284__F5 | The mechanism of retinoic acid stimulation of NIS expression by modifying signal transduction pathways in breast cancer and thyroid cells, based on the results of the inhibitor studies |
| PMC2386416__F1 | Illustrations of the 5 Alpha-reductase action and the pathway of androgen action on target gene expression |
| PMC2386920__F7 | IRF-5 in the innate antiviral response |
| PMC2387053__F2 | Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit? |
| PMC2387183__F4 | Autocrine/paracrine induction of osteogenesis in hMSCs by PKA signaling |
| PMC2390552__F11 | ERK1 and ERK2 knockdown differently affect signals involved in patterning of the early embryo |
| PMC2390552__F6 | Analysis of Nodal signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390552__F7 | Analysis of FGF signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390552__F8 | Analysis of Wnt signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390552__F9 | Analysis of BMP signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390572__F10 | MCF10A Pathway 2 affected by TFIIS knockdown |
| PMC2390572__F8 | Major pathways affected by TFIIS knockdown in MCF7 |
| PMC2390572__F9 | MCF10A Pathway 1 affected by TFIIS knockdown |
| PMC2391069__F1 | Overindulgence and metabolic syndrome: is FoxO1 a missing link? |
| PMC2391280__F1 | A signaling pathway AKTing up in schizophrenia |
| PMC2393790__F3 | Citrate cycle genes are up-regulated in the brains of nurse bees |
| PMC2394659__F3 | Aged Retinal Pigment Epithelium/Choroid: A Potential Substratum for the Pathogenesis of Age-Related Macular Degeneration |
| PMC2394714__F10 | TGFB1-induced PAI-1 expression in VSMC |
| PMC2394752__F4 | Contextual organization of the NFKB positive modulators |
| PMC2394768__F4 | Network diagram comprising genes and functional processes associated with regulated AS events in the CNS |
| PMC2395193__F3 | Gene networks identified in both recEbo-VP35/WT- and recEbo-VP35/R312A-infected cells compared to mock-infected and irradiated controls |
| PMC2395337__F1 | 5-Fuorouracil drug pathway demonstrating the interaction of multiple gene products |
| PMC2396219__F2 | PPARA and AMPK activities in the cancer cells exposed to energetic stress |
| PMC2396493__F1 | P53 on the IGF-1 signaling pathway |
| PMC2397440__F8 | Possible role of AICAR and compound C on the AMPK pathway and on glycolysis in CT-2A and astrocytes under low glucose conditions |
| PMC239898__F6 | Activation of the MAPK signaling pathway by FSH, ATP and GnRH in ovarian cancer |
| PMC2405801__F2 | Description of possible involved signalling pathways |
| PMC2405914__F4 | Catenins: Keeping Cells from Getting Their Signals Crossed |
| PMC2408406__F1 | Microvasculature in the pathogenesis of inflammatory bowel disease |
| PMC2408433__F1 | Glucose transport regulation by the Akt/TSC pathway |
| PMC2408969__F8 | Deciphering the Ubiquitin-Mediated Pathway in Apicomplexan Parasites: A Potential Strategy to Interfere with Parasite Virulence |
| PMC2409554__F1 | PC12 cell model of neuronal differentiation |
| PMC2409614__F3 | Development of tamoxifen (TAM)-resistant breast cancer and the changing role of oestradiol (E2) in the life and death of ER-positive cancer cells |
| PMC2409816__F1 | Schematic representation of the major pathways of ganglioside biosynthesis |
| PMC2410042__F2 | Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival |
| PMC2410087__F1 | Example of EGFR-mediated signaling changes, a commonly disrupted pathway in lung cancer |
| PMC2410298__F1 | TOLL-LIKE RECEPTORS REGULATION OF VIRAL INFECTION AND DISEASE |
| PMC2413058__F7 | Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor |
| PMC2413267__F1 | Wnt Signaling and Skeletal Development |
| PMC2413330__F3 | Working hypothesis on the mechanism by which plasminogen activator inhibitor-1 (PAI-1) causes hepatic steatosis |
| PMC2417166__F8 | Wnt signaling pathways in INS-1 cells |
| PMC2417187__F7 | Activation of the UPR in the absence of H6PD |
| PMC2423292__F6 | Musashi1 signaling in mammary progenitor cell proliferation |
| PMC2423434__F5 | Dynamically asserted instances of interactions |
| PMC2423615__F4 | A Regulatory Role for NBS1 in Strand-Specific Mutagenesis during Somatic Hypermutation |
| PMC2423668__F1 | Two branches of TLR downstream signaling |
| PMC2424193__F6 | Chemical Rescue of ÃŽâ€F508-CFTR Mimics Genetic Repair in Cystic Fibrosis Bronchial Epithelial Cells |
| PMC2424235__F1 | Auxin signaling |
| PMC2424294__F2 | Induction and lifetimes of signal transduction proteins (and their mRNAs) at various positions in signal transduction networks |
| PMC2424295__F2 | Feedback loops in NFKB signaling |
| PMC2427336__F9 | A schematic summarizing ER stress response pathways in cells compensating for deficiency of the ER stress response kinase, PERK |
| PMC2427358__F8 | Summary of GRTH impact in apoptotic pathways in germ cells |
| PMC2430411__F2 | Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine |
| PMC2430503__F1 | Resistance to ErbB-targeted cancer therapeutics |
| PMC2430594__F1 | Cartoon of two of the most promising DNA repair pathways for cancer therapeutics |
| PMC2430620__F1 | Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate |
| PMC2430694__F2 | Inflammatory Pain: The Cellular Basis of Heat Hyperalgesia. |
| PMC2430908__F8 | Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity |
| PMC2432084__F9 | p27Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells |
| PMC2433332__F3 | T-cell polarizing factors |
| PMC2435243__F9 | Several signaling pathways work together in the TGFB1-induced expression of CCN2/CTGF in primary human gingival fibroblasts |
| PMC2435278__F2 | The Aedes aegypti Toll Pathway Controls Dengue Virus Infection |
| PMC2435380__F1 | Methionine metabolic pathway |
| PMC2435382__F11 | Hypothetical scheme illustrates the putative intracellular signaling cascades serving as the context for the data collected in the current study |
| PMC2435603__F8 | Potentiation of Nerve Growth Factor-Induced Neurite Outgrowth by Fluvoxamine: Role of Sigma-1 Receptors, IP3 Receptors and Cellular Signaling Pathways |
| PMC2435618__F2 | Pathways involved in cell differentiation, homeostasis and apoptosis in the adult intestinal epithelium, Beta-catenin and TCF4 are expressed in the proliferative compartment, where are located the intestinal epithelial stem cells |
| PMC2438299__F6 | Regulation of G1/S transition by the Cdh1/APC-Skp2-p27 cascade in colon cancer Cdh1/APC is critical in regulating Skp2-p27-cyclin E/CDK2 axis, resulting in averting abnormal entry of S phase |
| PMC2440410__F3 | Regulation of post-cushion valve maturation to thin fibrous leaflets also includes EGF receptor signalling in addition to differential signalling of the pathways in c |
| PMC2440498__F1 | Signaling cascades initiated via TLR2- and TLR4-dependent activation |
| PMC2441985__F3 | The regulation of the insulin signaling pathway by miRNA cluster mmu-mir-183-96-182 |
| PMC2442829__F1 | Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations |
| PMC2442829__F2 | Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations |
| PMC2442833__F1 | Metabolic network of oryza sativa L |
| PMC2443667__F1 | Connections between the SAM cycle, transsulfuration pathway, and glutathione production |
| PMC2443854__F1 | The Essential Components of Nodal SignalingTGFB proteins are synthesized as pre-pro-proteins requiring cleavage of the signal peptide (black) and prodomain (orange) prior to dimerization of active ligand (red diamonds) |
| PMC2446520__F1 | The GNB/LNB pathway and related enzymes |
| PMC2447903__F8 | TWEAK killing |
| PMC2448841__F5 | Proposed model of arrest of maturation/activation of DCs via ILT4 receptor and HLA-G ligand |
| PMC2453072__F3 | The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant |
| PMC2453100__F7 | The activated PI3K-AKT pathway and its downstream effectors that contribute to the tumorigenesis of TSHomas in TRBPV/PV mice |
| PMC2453756__F1 | Pathway of murine Th17 differentiation |
| PMC2453768__F8 | The regulation of catabolic and anti-anabolic actions of FGF2 in intervertebral disc cells |
| PMC2455793__F1 | Interaction between two known Egr1 target genes, PTEN and fibronectin achieves a delicate balance between attachment and apoptosis of detached cells (anoikis) |
| PMC2464594__F4 | Oct-4 Targets in the Wnt Signalling Pathway |
| PMC2469272__F2 | LPS signaling [modified from O'Neill and Bowie () with permission] |
| PMC2474812__F1 | Classical and back-door pathways of androgen biosynthesis |
| PMC2474943__F3 | Points of action of flavonoids within ERK pathway |
| PMC2474943__F4 | Points of action of flavonoids within JNK pathway |
| PMC2474943__F5 | Points of action of flavonoids within p38 pathway |
| PMC2474943__F7 | Points of action of flavonoids within PI3K/Akt signalling pathway |
| PMC2474948__F1 | Integration of the TGFB1 apoptotic signal by the lipid oxidation end-product 4-hydroxynonenal |
| PMC2475560__F3 | Adult stem cell maintenance and tissue regeneration in the ageing context |
| PMC2475804__F1 | The Role of UbiX in Escherichia coli Coenzyme Q Biosynthesis |
| PMC2476215__F3 | Brick by brick: metabolism and tumor cell growth |
| PMC2477698__F1 | Examples of the molecular mechanisms by which phytochemicals activate hormetic stress response pathways |
| PMC2480606__F1 | An outline of major signaling pathways leading to NFKB activation |
| PMC2480606__F2 | NFKB pathway in skeletal muscles |
| PMC2481274__F2 | Type I Interferon: Potential Therapeutic Target for Psoriasis? |
| PMC2483283__F2 | Coexpression of genes within three core metabolic pathways |
| PMC2483283__F4 | Coexpression of the genes for fatty acid biosynthesis |
| PMC2483283__F5 | Leucine degradation pathway in mitochondria |
| PMC2483757__F1 | Kinetic model of the EpoR/GATA-1 network implicated in erythrocyte progenitor commitment |
| PMC2484121__F2 | Small Integrin-Binding LIgand N-linked Glycoproteins (SIBLINGs): Multifunctional proteins in cancer. |
| PMC2490739__F8 | Scheme summarizing the differential effect of PARP-1 inhibition versus silencing on SSB repair via the BER pathway |
| PMC2490815__F2 | Regulation of neuroinflammation by PPAR agonists in CNS diseases |
| PMC2490815__F3 | Regulation of NFKB pathway by PPAR agonists in CNS diseases |
| PMC2490815__F4 | IL-12, IL-23 and IL-27 are heterodimeric cytokines signals through Jak-Stat pathway and induce Th1/Th17 differentiation and T-bet expression in T cells |
| PMC2491599__F2 | Wnt canonical signaling pathway |
| PMC2491599__F3 | Wnt signaling pathwhay in cervical cancer |
| PMC2491602__F6 | TNFA signaling pathway |
| PMC2491640__F5 | Regulatory network of important genes involved in EBV-dependent NPC |
| PMC2491704__F3 | Recycling pathway of acetylcholine (ACh) synthesis, release, action and breakdown at a cholinergic nerve terminal |
| PMC2491722__F4 | Gdnf signaling pathways within the mammalian spermatogonial stem cell niche |
| PMC2491722__F6 | Gdnf signaling pathways within the mammalian spermatogonial stem cell niche |
| PMC2492871__F4 | Networks top-ranked by Ingenuity Pathway analysis after knockdown of TP53 (A) and LSR1+TP53 (B) |
| PMC2492871__F5 | Networks top-ranked by Ingenuity Pathway analysis after knockdown of LSR1 (A-B) |
| PMC2492871__F6 | Networks top-ranked by Ingenuity Pathway analysis after knockdown of LSR2 (A-B) |
| PMC2493210__F1 | Schematic diagrams of small intestine mucosa in normal and infected intestines |
| PMC2494808__F3 | Graphical representation of connections between receptors and pathways implicated in NTS baroreflex modulation by pharmacological studies |
| PMC2494844__F2 | Genomic dissection of the cytokine-controlled STAT5 signaling network in liver |
| PMC2495063__F3 | Germline Mutations and Variants in the Succinate Dehydrogenase Genes in Cowden and Cowden-like Syndromes. |
| PMC2496917__F1 | Interfering the PI3K/mTOR/p70S6K signaling pathway |
| PMC2500163__F4 | HIV Replication Enhances Production of Free Fatty Acids, Low Density Lipoproteins and Many Key Proteins Involved in Lipid Metabolism: A Proteomics Study |
| PMC2504760__F1 | Mechanisms by which diabetes increases cardiovascular disease |
| PMC2515131__F2 | Signal transduction events initiated by Kit and FcERI leading to specific mast cell responses, and the integration of these pathways for the synergistic enhancement of mast cell mediator release |
| PMC2515306__F1 | Wnt signaling pathway and its inhibition by AB aggregates |
| PMC2515336__F2 | Representation of the two NFKB signaling pathways |
| PMC2515524__F8 | Insulin/FoxO1, TGFB1/Smad, and TNFA/cJun signaling pathway crosstalk in coordinated regulation of bile acid synthesis in the cholestatic liver injury, fibrogenesis, and regeneration |
| PMC2515553__F1 | Ischemic Preconditioning And Myocardial Infarction: An Update and Perspective |
| PMC2515624__F1 | Implications of hedgehog signaling antagonists for cancer therapy |
| PMC2515871__F2 | Roles of cis- and trans-Changes in the Regulatory Evolution of Genes in the Gluconeogenic Pathway in Yeast |
| PMC2516358__F7 | Time ordered sequential events control cellular decision of migration |
| PMC2516940__F2 | Sepsis and insights from clinical trials |
| PMC2517296__F1 | The co-ordinated activation of pro-inflammatory signalling pathways by TLR ligands and the pro-inflammatory cytokines TNFA, IL-1 and IFN |
| PMC2517590__F2 | Schematic overview of the integrin signaling |
| PMC2517664__F2 | A simplified diagram of the key type-1 cytokine/receptor interactions relevant for immunity against intracellular bacteria, derived from published gene knockout mouse studies |
| PMC2517702__F3 | Signal transduction in the CD95 pathway |
| PMC2517789__F1 | Cytokines and their receptors in cardiovascular diseases |
| PMC2517789__F2 | Two pathways from gp130 to hypertrophic gene expression |
| PMC2518073__F8 | Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer |
| PMC2518078__F1 | Cotargeting survival signaling pathways in cancer |
| PMC2518081__F3 | The pathways involved in polycystic kidney disease |
| PMC2518463__F2 | Binding of specific signalling proteins to phosphorylated tyrosine residues on KIT following receptor activation and the subsequent signalling events leading to mast cell responses |
| PMC2518687__S2 | Total synthesis of rac-cinnabaramide A (4) |
| PMC2518687__S3 | Total synthesis of rac-salinosporamide A (3) |
| PMC2518924__F9 | The CEBPD network |
| PMC2519092__F2 | Cellular responses after six hours exposure to L |
| PMC2519122__F1 | Role of mTOR in anticancer drug resistance |
| PMC2519541__F2 | Integration of the AinS-AinR and LuxI-LuxR quorum sensory pathways |
| PMC2519632__F6 | Proposed model of KSHV-induced lymphatic reprogramming of endothelial cells |
| PMC2522268__F1 | Interferon-inducible antiviral effectors |
| PMC2522278__F2 | Comparative Analysis of mRNA Targets for Human PUF-Family Proteins Suggests Extensive Interaction with the miRNA Regulatory System |
| PMC2525561__F4 | Schematic diagram of in vivo n3 VLC-PUFA biosynthetic pathway mediated by ELOVL4 and other ELO families [modified after Suh and Clandinin ()] |
| PMC2527273__F2 | The signaling pathway of Type II, FasL signaling-induced apoptosis, adapted from Bagci et al |
| PMC2527618__F4 | Graphic illustrating the roles of 8 genes implicated in the present study in lithium-sensitive signaling pathways |
| PMC2528242__F1 | Peroxisome proliferator-activated receptorG and ligands: pathways and functions |
| PMC2528845__F2 | Intracellular signaling activated through FGFRs |
| PMC2528845__F4 | Opposing signals regulate sex determination in the bipotential gonad |
| PMC2528847__F2 | Integration of genomic and nongenomic/rapid ER signaling and its crosstalk with growth factor receptor and cell kinase pathways in endocrine resistance: a working model |
| PMC2528859__F2 | The UPR sensors PERK, IRE1A, and ATF6 control mRNA translation and transcriptional induction of UPR-regulated genes |
| PMC2529154__F4 | Four components to yield MDP chromophore |
| PMC2529314__F7 | Interactions of KEGG pathways for differentially expressed genes in different stages of PAD |
| PMC2529314__F8 | Over-representation of Toll-like receptor signaling pathway genes |
| PMC2530034__F1 | Transcriptional regulation and the pathway of RNA polymerase II transcription |
| PMC2531163__S3 | Developmental signaling pathways |
| PMC2533023__F5 | Response of A549 cells exposed to crocidolite |
| PMC2533092__F1 | Metabolic pathways for the synthesis of phospholipids and neutral lipid classes in S |
| PMC2533145__F10 | Rap1 and glycolytic/TCA cycle reaction |
| PMC2533280__F1 | Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood |
| PMC2533786__F9 | PI 3-kinase/AKT-dependent pathways involved in IL-1 induction of IL-6 |
| PMC2536507__F2 | Pathogen recognition systems |
| PMC2536824__F4 | Ingenuity Pathway Analysis (IPA) of genes specifically overexpressed in B1-Arg389 transgenic mouse hearts |
| PMC2536868__F7 | Pathways for major lipid metabolism |
| PMC2537559__F3 | Glycolysis pathway |
| PMC2537559__F4 | Alterations in extraceullular matrix and secreted proteins associated with metastatic cancer |
| PMC2537559__F5 | Alterations in adhesion-mediated signaling and cytoskeleton remodeling in metastatic cancer |
| PMC2537575__F5 | NFKB canonical signaling pathway from IPA |
| PMC2538513__F2 | The involvement of death receptor pathway (right half) and mitochondrial pathway mediated (left half) apoptosis in nurse cell formation |
| PMC2538513__F4 | Schematic illustration of the involvement of c-Ski and TGFB signaling pathway in nurse cell formation |
| PMC2538516__F1 | Biosynthetic relationships between amino acids, as defined by their biosyntheses and their relationships with the glycolytic pathway and the citric acid cycle |
| PMC2542903__F6 | Proposed EphB2 signaling network |
| PMC2543934__F5 | PPARG in Type 1/Type 2 T (NK) cell differentiation |
| PMC2546860__F2 | Glycerol biosynthesis and other major pathways contributing to cytosolic NAD+/NADH balance in S |
| PMC2546909__F1 | Signal transduction pathway elicited by Env interaction with CCR5 required for Rac-1 activation and membrane fusion |
| PMC2547491__F1 | IL-6 signaling and therapeutic targets in CCA |
| PMC2547860__F6 | Networks among genes involved in milk fat synthesis |
| PMC2552992__F9 | Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease |
| PMC2553363__F1 | Extrinsic and intrinsic pathways of hepatocyte apoptosis |
| PMC2553363__F2 | ER stress pathway |
| PMC2553572__F2 | DSB repair pathways |
| PMC2553712__F1 | Design, Synthesis and Characterization of A Potent, Non-Peptide, Cell-Permeable, Bivalent Smac Mimetic that Concurrently Targets both the BIR2 and BIR3 Domains in XIAP |
| PMC2556095__F4 | TGFBeta-related signalling pathway controlling Myc activity in keratinocytes |
| PMC2556095__F6 | In the canonical TGFB signalling pathway, ligands signal through type I and II transmembrane protein kinase receptors |
| PMC2556249__F2 | Insulin receptor signaling |
| PMC2556273__F8 | Peptides identified in the insulin/insulin-like growth factor 1 signaling pathway can be used as proteotypic peptides in future targeted analyses |
| PMC2556276__F1 | Display of differentially expressed genes in the uterine cervix after term spontaneous labor mapped on the PLAU signaling pathway |
| PMC2556568__F2 | Molecular processes that handle – and mishandle – dietary lipids |
| PMC2556809__F5 | Metabolic model used for the determination of intracellular fluxes |
| PMC2556866__F1 | Telomere structure and DSB processing |
| PMC2559887__F2 | Ingenuity pathway analysis on AP-1 related gene network |
| PMC2559887__F3 | Ingenuity pathway analysis on NFKB related gene network |
| PMC2559911__F7 | Model for the function of SHC-1 in IIS and JNK signaling |
| PMC2561291__F1 | Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions |
| PMC2561291__F5 | Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions |
| PMC2561962__F1 | Ischemia induces cell death by several distinct pathways, and Hsp70 reduces all of these |
| PMC2562038__F3 | The Shh signaling pathway |
| PMC2562925__F8 | Schematic depicting the roles of p53 and wnt7b in proposed pathway for NGF-mediated neurite outgrowth in PC12 differentiation |
| PMC2562939__F1 | The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin |
| PMC2563180__F3 | The cardiofaciocutaneous syndrome |
| PMC2564730__F3 | Use of MIMO models to infer regulatory interactions in breast cancer cells |
| PMC2564980__F5 | Genes with differential expression in the carcinoma and papillary adenocarcinoma tumors were assembled into distinct metabolic pathways |
| PMC2564980__F7 | Higher expression of genes involved in O-glycan synthesis in the carcinoma compared to the papillary adenocarcinoma tumors |
| PMC2565686__F6 | Merger of the interaction maps for the three human proteins ING1, MEKK, and p38a (p38MAPK) based on empirical data retrieved from the STRING database |
| PMC2566006__F2a | A Defect in Menadione Biosynthesis Induces Global Changes in Gene Expression in Staphylococcus aureus . |
| PMC2566525__F8 | Schematic view of part of the IGF-1 and integrin signaling pathway genes transcribed by hNCC |
| PMC2566927__F2 | Essence of retrograde signaling in model organisms |
| PMC2567351__F1 | T Cell Receiptor Signaling Pathway |
| PMC2567351__F2 | MAPK Signaling Pathway |
| PMC2567408__F8 | NCAM upregulation leads to a functional switch |
| PMC2567511__F1 | The tetrapyrrole pathway in plants showing intermediates and genes analyzed in this study |
| PMC2570214__F8 | Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2-/- Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM |
| PMC2570299__F3 | Role of GalGlyNAcPVv in V |
| PMC2570545__F2 | EGFR signalling pathway in lipid rafts |
| PMC2570554__F4 | Anti-apoptotic mechanism of survival and growth of serum-starved 5637 human bladder carcinoma cells |
| PMC2570606__F6 | Proposed model for the effects of hypoxia-induced energy stress on them TOR pathway in HNSCC cells |
| PMC2570700__F2 | MOLECULAR TARGETED THERAPIES FOR PANCREATIC CANCER |
| PMC2570709__F1 | Rogue proliferation versus restorative protection: Where do we draw the line for Wnt and Forkhead signaling? |
| PMC2571037__F1 | Anticancer therapy: boosting the bang of Bim |
| PMC2572128__F1 | Simplified model of translation initiation |
| PMC2572856__F1 | Aging of signal transduction pathways, and pathology |
| PMC2572865__F1 | Hematopoietic niche and bone meet |
| PMC2573957__F1 | Association of Interacting Genes in the Toll-Like Receptor Signaling Pathway and the Antibody Response to Pertussis Vaccination |
| PMC2574011__F1 | Store-operated Ca2+ entry in T cells |
| PMC2574672__F2 | Iron-sulfur (Fe-S) cluster biogenesis in eukaryotes |
| PMC2574839__F1 | Therapeutic targets of the AR pathway |
| PMC2574839__F2 | Androgen synthesis pathway and therapeutic targets |
| PMC2575163__F8 | Signaling pathway for proceeding from FosB toward thrombospondin 1/TGFB1 |
| PMC2575183__F7 | Proposed signaling mechanism that stimulates EMT |
| PMC2575400__F2 | MiRNA Signature of Prion Induced Neurodegeneration |
| PMC2575467__F5 | A model of KCNQ1/KCNE1 function in embryogenesis |
| PMC2575513__F2 | Diversification of the innate immune arsenal in amphioxus |
| PMC2575530__F2 | Insulin-like growth factor-I signaling pathway involved in breast cancer |
| PMC2575612__F4 | Inter-individual mRNA expression variances in the mitogen-activated protein kinase (MAPK) signaling pathway in rheumatoid arthritis (RA) compared with normal control (NC) |
| PMC2575629__F3 | Alternative pathway of NFKB activation |
| PMC2575728__F2 | Following the cytokine signaling pathway to leukemogenesis: a chronology |
| PMC2575803__F1 | Most prominently involved biological pathways in OSCC |
| PMC2575825__F4 | Glutathionine (GSH) redox network |
| PMC2575825__F9 | Redox-sensitive steps in hypothetical redox signaling pathways |
| PMC2575845__F1 | RLR signaling pathway and its negative regulatory molecules |
| PMC2575905__F1 | Current concepts of the amino acid signaling pathway leading to protein synthesis |
| PMC2576041__F9 | The role of the IGF-1/phosphatidylinositol 3-kinase (PI3K)/Akt pathway and atrogin-1 and MuRF-1 in SI-induced atrophy and in the amelioration of atrophy by high-load isometric contractions |
| PMC2576557__F10 | Schematic diagram showing the pathway involved in high glucose- and high insulin-induced extracellular matrix protein synthesis mediated by GSK3B and eIF2BE |
| PMC2576563__F7 | Tight regulation of MUC5AC mucin induction by pneumolysin via PAK4-JNK and MKP1 signaling pathways |
| PMC2577004__F1 | Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-ALL |
| PMC2577137__F1 | Cross talk between PKA, PI3K/AKT and WNT/CTNNB1 intracellular signaling pathways |
| PMC2577435__F9 | Signaling from LMP1 and TLR to IRF7 activation |
| PMC2577687__F1 | Metabolic scheme |
| PMC2577715__F15 | Notch, Wnt, and SHH signaling pathways |
| PMC2577715__F4 | NFKB signaling and MDR gene expression |
| PMC2577715__F9 | Nrf2 and transcriptional regulation of Gamma-GCSh expression |
| PMC2577794__F1 | Uncovering cryptic genetic variation in C |
| PMC2578840__F8 | Proposed signaling pathway |
| PMC2579334__F3 | Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure |
| PMC2579774__F4 | HIV-1 infected astrocytes and the microglial proteome |
| PMC2581573__F1 | The IL-1 signaling pathway |
| PMC2581748__F2 | Activation of the mammalian target of rapamycin (mTOR) pathway can result from numerous glioma-associated genetic changes |
| PMC2581770__F3 | TNFR and LTBR signaling pathways for NFKB activation |
| PMC2581785__F1 | Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum |
| PMC2581798__F3 | Information flow through the JNK network |
| PMC2582196__F2 | Classic renin-angiotensin-aldosterone system (RAAS) pathway and angiotensin II (Ang II)/insulin signaling in the vascular smooth muscle cell |
| PMC2582888__F8 | Two parallel pathways are required for Abl-dependent cell detachment |
| PMC2583357__F1 | ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY |
| PMC2583357__F3 | ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY |
| PMC2583475__F1 | Simplified native E |
| PMC2583496__F2 | Global regulation of the E |
| PMC2583931__F1 | Migrating D-loop model of recombination |
| PMC2584013__F23 | TNF-induced and ROS-dependent events in target cells: the role of JNK activation in mediating cell death |
| PMC2584013__F25 | ER stress and ROS in NAFLD/NASH |
| PMC2584165__F2 | Highly simplified diagram of signaling pathways involving Beta-catenin that may be relevant for RPE cell morphogenesis and susceptibility to age-related oxidative stress |
| PMC2584809__F6 | Schematic model illustrating constitutive vs |
| PMC2585009__F4 | HIV-1 Activates Macrophages Independent of Toll-Like Receptors |
| PMC2585009__F7 | HIV-1 Activates Macrophages Independent of Toll-Like Receptors |
| PMC2585593__F1 | Diagrammatic representation of pathways associated with aroma production and links to associated metabolic activities |
| PMC2585609__F1 | A schematic representation of the functional domains of Stim and Orai proteins |
| PMC2586079__F1 | COMPLEMENT ACTIVATION FRAGMENT Bb IN EARLY PREGNANCY AND SPONTANEOUS PRETERM BIRTH |
| PMC2586109__F1 | Protein kinase C isozymes as therapeutic targets for treatment of human cancers |
| PMC2586270__F6 | Furin action in pituitary gonadotrope cells |
| PMC2586335__F1 | Ras signalling pathways |
| PMC2586899__F4 | The involvement of TNFAlpha-mediated signaling pathways in insulin resistance |
| PMC2586935__F4 | TGFB pathway as affected by IGF2 administration based on Pathway-Express |
| PMC2587085__F1 | Targeting EGFR and Src Pathways in Head and Neck Cancer |
| PMC2587278__F1 | Oxidative and alkylation DNA damage is effectively repaired by the DNA BER pathway |
| PMC2587303__F1 | mTOR inhibition as a Therapeutic Strategy in the Management of Urologic Malignancies |
| PMC2588608__F2 | Pathway Annotation and Summary Hit Table |
| PMC2590699__F1 | Current model for Okazaki fragment maturation |
| PMC2592633__F1 | RNAi pathways in Drosophila |
| PMC2592774__F1 | TLR signalling pathways |
| PMC2592794__F1 | Monosodium urate (MSU) crystals activate monocytes via the Toll-like receptor (TLR) pathway and the inflammasome |
| PMC2592809__F9 | Scheme summarises different intracellular pathways during osteoblast differentiation which include promoting (blue) and inhibiting (red) factors and are mainly mediated by Smad proteins |
| PMC2593006__F3 | Signalling pathways underlying neuronal survival and cognitive performance |
| PMC2593012__F3 | Gene expression data mapped on the mouse insulin signaling pathway |
| PMC2593023__F1 | Unexpected pieces to the senescence puzzle |
| PMC2593077__F2 | Hepatitis C and Innate Immunity - Recent Advances |
| PMC2593123__F1 | A simplified schematic of the core left-right signaling pathway in the e8.5 (6 somite) mouse embryo |
| PMC2593438__F7 | AKT reduces the growth-inhibitory function of TGFB1 |
| PMC2593440__F3 | Network of differentially expressed genes in the cell cycle control pathway in sorted R1/R2 Eklf-/- E13.5 fetal liver cells |
| PMC2593475__F1 | PI3K/PTEN/Akt/mTOR Pathway |
| PMC2593565__F3 | Epithelial barrier function by lactobacilli |
| PMC2593566__F3 | JAK/STAT signaling pathway and SARS-CoV |
| PMC2594010__F2 | Regulation of metastasis in colorectal adenocarcinoma: A collision between development and tumor biology |
| PMC2596245__F3 | EET- or sEHI-mediated antihyperalgesia occurs through 2 distinct mechanisms |
| PMC2596750__F8 | TNFR1 and LTBR ligation-induced signaling in vascular EC |
| PMC2596919__F2 | Obesity and Free Fatty Acids (FFA) |
| PMC2597184__F2 | Nuclear Factor-kappa B Signaling in Skeletal Muscle Atrophy |
| PMC2597223__F1 | Pathways of apoptosis |
| PMC2597498__F2 | TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway |
| PMC2597730__F7 | Cascade between VEGFA, a direct target of BP1, and its downstream target genes in cell proliferation |
| PMC2597805__S12 | Completion of the lipid II synthesis |
| PMC2597805__S3 | Chemical synthesis UDP-N-acetylmuramyl pentapeptide (Park nucleotide) |
| PMC2597811__F1 | Molecular Genetics of Colorectal Cancer: An Overview |
| PMC2597859__F1 | Role of Programmed Cell Death in the Immunopathogenesis of Sepsis |
| PMC2600414__F1 | The PTEN/AKT Pathway in NOTCH1-induced leukemia |
| PMC2600462__F5 | Morphoproteomic Evidence of Constitutively Activated and Overexpressed mTOR Pathway in Cervical Squamous Carcinoma and High Grade Squamous Intraepithelial Lesions. |
| PMC2600469__F4 | Genes regulated by SHP in PPAR signaling pathway |
| PMC2600644__F4 | Pathway schematic of significantly regulated genes in (A) NFKB signalling and (B) MAP kinase signalling |
| PMC2600878__F6 | Syk signaling is necessary for E-selectin-induced LFA-1-ICAM-1 association and rolling but not arrest |
| PMC2601639__F1 | Membrane Recruitment as a Cancer Mechanism: A Case Study of Akt PH Domain |
| PMC2601664__F1 | Membrane-initiated Estrogen Signaling in Hypothalamic Neurons. |
| PMC2601665__F1 | Hh-Gli pathway and the Gli code in tissue patterning and stem-cell lineages |
| PMC2603035__F3 | Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease |
| PMC2603135__F5 | Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data |
| PMC2603135__F6 | Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data |
| PMC2603427__F5 | Hierarchical layout of the EGFR1 pathway downloaded from the HPRD pathway database [] |
| PMC2603427__F6 | Hierarchical layout of the B-cell receptor pathway downloaded from the HPRD pathway database [] |
| PMC2603471__F1 | Ageing, oxidative stress and cancer: paradigms in parallax |
| PMC2603552__F10 | Role of oxysterol sulfation in lipid metabolism |
| PMC2604897__F2 | Putative biochemical pathways involving MGAT3 |
| PMC2605486__F3 | Progressive changes in progenitor cells during motor neuron development |
| PMC2605486__F4 | Olig2 and the transcription factor network controlling motor neuron differentiation |
| PMC2605487__F2 | Signalling pathways involved in the induction of astrocyte specification/differentiation |
| PMC2605641__F2 | Nrf2-ARE Pathway: An Indicator and Modulator of Oxidative Stress in Neurodegeneration |
| PMC2605643__F6 | Working model of the Smac-mimetic IAP-inhibitors in radiosensitization |
| PMC2605957__F7 | Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway |
| PMC2606015__F9 | Schematic view of the Vav family-regulated signaling pathways of DT40 B-cells |
| PMC2607021__F4 | Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease |
| PMC2607051__F7 | ATR and Chk1 Suppress a Caspase-3-Dependent Apoptotic Response Following DNA Replication Stress |
| PMC2607114__F1 | TFPI anti-coagulant and anti-inflammatory activities |
| PMC2610122__F1 | Classical view of three independent Wnt signalling pathways |
| PMC2610259__F1 | Chronic colon colitis model |
| PMC2610675__F6 | Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells |
| PMC2612083__F1 | Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder |
| PMC2612524__F7 | A potential model for contributions of F-BAR-containing adaptor proteins and PTKs in regulating FcɛRI signaling during internalization |
| PMC2612755__F5 | A theoretical pancreatic endocrine tumor cell, smooth muscle cell (pericyte) or endothelial cell demonstrating the sites and mechanism of action of novel agents for the management of metastatic PETs |
| PMC2612938__F2 | Pathways by which Mgrn1-mediated ubiquitination could modulate melanocortin receptor regulation of pigment production and energy metabolism |
| PMC2613033__F1 | Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study |
| PMC2613061__F1 | IGFs in the peripheral nervous system |
| PMC2613125__F6 | Interleukin-6 and Neural Stem Cells: More Than Gliogenesis. |
| PMC2613456__F9 | TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4 |
| PMC2613471__F1 | Revisiting Notch in remyelination of multiple sclerosis lesions |
| PMC2613484__F3 | Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways |
| PMC2613484__F7 | Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways |
| PMC2613770__F1 | Canonical and noncanonical NFKB signaling pathways |
| PMC2613883__F1 | Simplified schematic drawing of the TGF-Beta-Smad pathway |
| PMC2613930__F4 | Genes that contain the 100 most differentially methylated CpG sites between normal and lung cancer tissue samples (p-value < 0.005) |
| PMC2614485__F6 | A simplified Hh signaling pathway, constructed from combined Drosophila and mammalian data |
| PMC2615236__F1 | Regulation of IGF-I Function by Proinflammatory Cytokines: At the Interface of Immunology and Endocrinology |
| PMC2615463__F1 | Arc function in mGluR-LTD |
| PMC2615542__F2 | Luteolin, a flavonoid with potentials for cancer prevention and therapy |
| PMC2615558__F4 | Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus |
| PMC2617762__F6 | Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia |
| PMC261890__F8 | T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression |
| PMC2620272__F4 | Bimodal genes that were switched "on" as a result of HIV infection in KEGG T-cell receptor signalling pathways |
| PMC2621002__F3 | Quantitative Proteomics Analysis of Macrophage Rafts Reveals Compartmentalized Activation of the Proteasome and of Proteasome-mediated ERK Activation in Response to Lipopolysaccharide |
| PMC2623309__F1 | Multiple feedback loops of p53 pathway |
| PMC262380__F9 | Free p65 can protect against TNF-Alpha-induced apoptosis in the absence of IKK activity |
| PMC2624576__F1 | Alternative splicing in the NFKB signaling pathway |
| PMC2626169__F1 | A simplified view of the sex-determination pathway in XX animals (A) and XO animals (B) |
| PMC262680__F1 | Microarray summary of proteasome subunits induced in mouse liver by D3T |
| PMC2627520__F2 | Biosynthesis of Natural and Hyperelongated Chondroitin Sulfate Glycosaminoglycans: New Insights into an Elusive Process |
| PMC2627788__F5 | Wnt/Beta-catenin signaling pathway in leukemia |
| PMC2628375__F7 | Hypothetical scheme of activation of the murine Hamp1 promoter |
| PMC2628394__F15 | Biological network representing the schizophrenia p-value ranking |
| PMC2628394__F16 | Biological network representing the bipolar disorder p-value ranking |
| PMC2629585__F7 | Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response |
| PMC2629979__F1 | Molecular Mechanisms in COPD pathogenesis and potential therapeutic targets |
| PMC2630373__F1 | Regulation of G1/S transition by growth factor (insulin and IGF-I) signaling in Beta-cells |
| PMC2630471__F5 | DAF-2 Insulin-like Signaling Pathway Independently Regulates Aging and Immunity |
| PMC2631022__F1 | ECM-receptor interaction pathway enriched by human switch-like genes |
| PMC2631033__F1 | Tumor necrosis factor and cancer, buddies or foes? |
| PMC2631307__F1 | Glucocorticoids and neonatal brain injury: the hedgehog connection |
| PMC2631308__F1 | Insulin resistance |
| PMC2631376__F3 | Hypothalamic Malonyl-Coenzyme A and the Control of Energy Balance. |
| PMC2631402__F4 | The Legionella pneumophila replication vacuole: making a cozy niche inside host cells |
| PMC2631405__F1 | Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models |
| PMC2631600__F1 | The HMGCR pathway |
| PMC2633067__F2a | Beyond Good and Evil in the Oral Cavity: Insights into Host-Microbe Relationships Derived from Transcriptional Profiling of Gingival Cells |
| PMC2633249__F3 | Enzymatic function of multiple origins regulates the progression of colorectal cancer and the development of metastases |
| PMC2633299__F11 | UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes |
| PMC2633398__F9 | An epistatic pathway and genetic model for replication slowing in fission yeast |
| PMC2633485__F8 | Proposed mechanism of PDGF signaling in the lens epithelial cells |
| PMC2633625__F2 | Toll-like receptors in skin |
| PMC2633716__F1 | Genetic Variation in Calcium Sensing Receptor (CASR) and Risk of Colon Cancer |
| PMC2634014__F1 | Possible mechanisms of tip cell selection through modulation of different components of the VEGF signalling pathway following Notch signalling |
| PMC2634101__F1 | Model summarizing some of the pathways described in this review leading to chemotaxis and cell motility |
| PMC2634254__F2 | Embryonic liver development |
| PMC2634254__F4 | Upstream regulators and downstream targets of Beta-catenin during embryonic liver development |
| PMC2634369__F1 | Ethylene signaling and salt stress response |
| PMC2634657__F2 | Leptin Neuroprotection in the Central Nervous System: Mechanisms and Therapeutic Potentials |
| PMC2634670__F1 | Strategies to inhibit the VEGF signalling pathway |
| PMC2634812__F3 | Stepwise respecification of ETP and DN2 cells by GATA-3 overexpression |
| PMC2634812__F4 | Myeloid diversion pathways for advanced pro-T cells by re-introduction of C/EBPA or PU.1 |
| PMC2634812__F5 | Schematic of counterbalancing and dose-dependent regulatory forces that act on T-cell precursors through the ETP and DN2 stages |
| PMC2634914__F1 | Pathway design |
| PMC2634968__F2 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling. |
| PMC2634968__F5 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling |
| PMC2634968__F6 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling |
| PMC2634968__F7 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling |
| PMC2634987__F1 | The GEP100-Arf6 pathway to invasion |
| PMC2635018__F1 | Amino acid transporters and nutrient sensing mechanisms |
| PMC2635020__F1 | CATHEPSIN D - MANY FUNCTIONS OF ONE ASPARTIC PROTEASE |
| PMC2635127__F1 | Erk non-Smad pathway |
| PMC2635127__F2 | JNK/p38 non-Smad pathway |
| PMC2635127__F3 | Small GTPase non-Smad pathway |
| PMC2635127__F4 | PI3K/Akt non-Smad pathway |
| PMC2635340__F2 | Kinetic Scheme for the 5-HT1AR and 5-HT2AR mediated MAP kinase activation pathway |
| PMC2635620__F2 | Inhibition of each signaling molecules by natural products in insulin signaling |
| PMC2635670__F1 | Apoptosis pathways: The extrinsic or death receptor pathway (left) is triggered by members of the death receptor superfamily such as Fas |
| PMC2636986__F1 | Adaptor protein containing pleckstrin homology (PH) domain, phosphotyrosine-binding (PTB) domain, and leucine zipper motif (APPL1)-mediated adiponectin and insulin-signaling pathways |
| PMC2637179__F2 | Role of IRS-1 in insulin and IGF-1 signaling |
| PMC2637184__F1 | New central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9 |
| PMC2637474__F7 | Hypothetical pathway involved in general cerebellum-mediated motor learning |
| PMC2637552__F1 | TGFB/SMAD signaling pathway |
| PMC2637651__F3 | Transcriptomes in Healthy and Diseased Gingival Tissues |
| PMC2637758__F5 | Pathways and networks associated with HSPA9, PHB, and ABCB6 |
| PMC2637783__F1 | Toll-like receptor (TLR) signaling |
| PMC2637898__F2 | EGFR signaling pathways |
| PMC2637898__F3 | EGFR signal transduction pathways |
| PMC2637898__F4 | VEGF signaling pathways |
| PMC2639036__F1 | Single-strand break repair pathways |
| PMC2639448__F1 | Intrafollicular predictors and regulators of oocyte quality within the oocyte-somatic cell regulatory loop |
| PMC2639705__F9 | Two Chromogranin A-Derived Peptides Induce Calcium Entry in Human Neutrophils by Calmodulin-Regulated Calcium Independent Phospholipase A2 |
| PMC2639747__F1 | Smad3 in TGFB-induced antiproliferative transcriptional responses |
| PMC2639747__F2 | Smad3 in TGFB-mediated proapoptotic transcriptional responses |
| PMC2639789__F9 | Summary diagram of E2 regulation of Wnt/Beta-catenin signaling pathway after cerebral ischemia and proposed role in E2 ischemic neuroprotection |
| PMC2640319__F1 | Insulin and amino acid signaling pathway leading to the stimulation of translation initiation |
| PMC2640456__F1a | Meta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes |
| PMC2640984__F3 | Distribution between short and long flap removal pathways |
| PMC2641000__F4 | Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary |
| PMC2642591__F1 | Retinoic acid dependent regulation of immune responses by dendritic cells and macrophages |
| PMC2642659__F2 | Visualization of molecular interaction and reaction networks in the KEGG database |
| PMC2642890__F2 | Posttranscriptional regulation of gene networks by GREs |
| PMC2643067__F1 | De novo purine biosynthesis pathway |
| PMC2643298__F11 | Herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by NGF deprivation through inhibition of caspase-3 activation and XIAP upregulation |
| PMC2643336__F3 | From the diet to the nucleus: Vitamin A and TGFB join efforts at the mucosal interface of the intestine |
| PMC2643928__F1 | Activation of the transcription factors IRF3 and NFKB in response to infection with a single-stranded RNA virus |
| PMC2643977__F4 | Proposed integrated model for local water transport inhibition by activation of P2Y2 and adenosine A1 receptors (A1R) in inner medullary collecting duct principal cell |
| PMC2644070__F2 | Homologies between mammalian and insect immune defense pathways |
| PMC2645295__F1 | Airway Smooth Muscle Cell as an Inflammatory Cell |
| PMC2645305__F3 | Airway Smooth Muscle Growth in Asthma |
| PMC2645538__F5 | Possible neuroprotective mechanisms of mild mitochondrial uncoupling and caloric restriction in neurodegenerative diseases |
| PMC2645860__F2 | Pathogenetic mechanisms of CCAAT enhancer binding protein alpha (C/EBPA) dysfunction |
| PMC2645904__F3 | Schematic representations of potential signaling pathways involved in serum-deprived retinal ganglion cell-5 cells |
| PMC2645908__F5 | Model showing RBR3 role in the RBR/E2F pathway controlling the expression of MCM2-7 genes, DNA replication, and cell transformation |
| PMC2646065__F8 | Proposed model involving GSK-3 inhibition and the mTOR pathway to stimulate human Beta-cell growth and proliferation |
| PMC2646147__F6 | A model for three pathways of TLS in mammalian cells |
| PMC2646278__F5 | Pathways of global genome nuclear excision repair (GG-NER) and transcription-coupled nuclear excision repair (TC-NER) |
| PMC2647162__F1 | APP processing and the production of the amyloidB peptides |
| PMC2647163__F3 | Advances on the Understanding of the Origins of Synaptic Pathology in AD. |
| PMC2647614__F2 | Novel Insights into Lung Transplant Rejection by Microarray Analysis |
| PMC2647628__F1 | CATERPILLER (NLR) Family Members as Positive and Negative Regulators of Inflammatory Responses |
| PMC2647780__F1 | Signaling Logic of Activity-Triggered Dendritic Protein Synthesis |
| PMC2647860__F7 | p53, Cyclin-dependent Kinase and Abnormal Amplification of Centrosomes |
| PMC2648232__F6 | Pathway mapping of OPC differentiation inducer genes |
| PMC2648516__F1 | SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification |
| PMC2648546__F8 | A new feedback loop for p53 pathway |
| PMC2648620__F2 | Insights into the Roles of Gut Microbes in Obesity. |
| PMC2649086__F7 | KLF14-mediated TGFBRII silencing |
| PMC2649208__F2 | Molecular interaction map displaying the functional interaction of genes in the MEK/ERK output profile with established roles in ERK signaling |
| PMC2649265__F8 | Insulin-PI3K-Akt signaling in AD |
| PMC2649302__F2 | Wnt/-catenin signaling pathway |
| PMC2649302__F3 | Conversations between Wnt/Beta-catenin and MAPK signaling pathways |
| PMC2649808__F5 | Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions |
| PMC2649968__F4 | Participation of DNA repair in the response to 5-fluorouracil |
| PMC2650010__F1 | Akt-dependent and independent mechanisms of mTOR regulation in cancer |
| PMC2650010__F2 | Akt-dependent and independent mechanisms of mTOR regulation in cancer |
| PMC2650010__F3 | Akt-dependent and independent mechanisms of mTOR regulation in cancer |
| PMC2650409__F6 | c-Src Regulates Akt Signaling in Response to Ghrelin via Beta-Arrestin Signaling-Independent and -Dependent Mechanisms |
| PMC2650609__F6 | Top network of upregulated genes in quadriceps muscles of COPD patients, compared with control subjects |
| PMC2650802__F7 | The Elg1-RFC Clamp-Loading Complex Performs a Role in Sister Chromatid Cohesion |
| PMC2651172__F7 | Possible site for alcohol-induced inhibition of muscle protein synthesis |
| PMC2651433__F2 | A nuclear SIRT1 mechanism for delaying NAD-ATP depletion through inhibition of PARP-1 is presented |
| PMC2651433__F4 | The Importance of NAD in Multiple Sclerosis. |
| PMC2651582__F1 | Metabolic reprogramming in tumor cells |
| PMC2651818__F3 | Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network |
| PMC2652039__F8 | Tumor Necrosis Factor-like Weak Inducer of Apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta activated kinase 1 |
| PMC2652310__F1 | Anaerobic metabolic pathways in C |
| PMC2652397__F1 | Dual Roles of Nrf2 in Cancer |
| PMC2652403__F1 | Signalling through the phosphatidylinositol 3-kinase (PI3K) affects cell growth, apoptosis and cell cycle regulation |
| PMC2652645__F1a | Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning |
| PMC2652867__F1 | PML regulon model is used to explain the effects of the PML protein and PML nuclear bodies on survival signaling as described in the text |
| PMC2653092__F5 | Basic Helix-Loop-Helix Factor Hand2 Regulates Autonomic Nervous System Development |
| PMC2653380__F3 | Schematic representation of bile acid synthesis by the classical neutral pathway |
| PMC2653622__F2 | PRIMARY CILIUM: AT THE CROSSROADS OF MAMMALIAN HEDGEHOG SIGNALING |
| PMC2654353__F5 | From nutrients to HIF and from HIF to metabolism |
| PMC2654353__F7 | From the extracellular matrix to HIF and from HIF to the extracellular matrix |
| PMC2654411__F3 | Time-course Comparison of Xenobiotic Activators of CAR and PPARα in Liver |
| PMC2654411__F6 | Time-course Comparison of Xenobiotic Activators of CAR and PPARA in Mouse Liver |
| PMC2654418__F6 | Crosstalk between the Androgen Receptor and Beta-Catenin in Castrate Resistant Prostate Cancer |
| PMC2654747__F2 | Summary of enzyme-catalyzed thyronamine deiodinase reactions |
| PMC2654975__F1 | Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease |
| PMC2655244__F8 | Proposed model for the signaling pathway of Cao-induced keratinocyte differentiation |
| PMC2655360__F7 | Pathway maps generated using GenMapp depicting increased glycolytic protein expression in differentiated intestinal epithelial cells relative to crypt cells |
| PMC2655379__F8 | Potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle |
| PMC2655678__F1 | ATM activation in response to DNA DSBs |
| PMC2655983__F3 | Simplified version of colorectal-cancer biological pathway in KEGG database for genes with mutation data in COSMIC |
| PMC2656226__F6 | Mitochondrial regulation of the apoptotic pathway is altered in disease and modulated by sirolimus treatment |
| PMC2656226__F9 | Complement pathway altered in disease |
| PMC2657106__F1 | Activation of the G2/M checkpoint after DNA damage |
| PMC2657416__F6 | A proposed model for the effect of ABA on BR signaling outputs |
| PMC2657476__F1 | ErbB Receptors in the Biology and Pathology of the Aerodigestive Tract |
| PMC2657775__F6 | Enrichment of Wnt signaling pathway |
| PMC2657775__F7 | Enrichment of TGF-beta signaling pathway |
| PMC2657775__F9 | Enrichment of Jak-STAT signaling pathway |
| PMC2657945__F1 | The TSC-mTOR signaling |
| PMC2657945__F2 | Regulation of the mTORC1 pathway by two distinct small GTPases |
| PMC2658089__F1 | The de novo and salvage pathways for purine nucleotide biosynthesis |
| PMC2658537__F1 | Sample signalling scheme showing pathways known to be active in melanoma |
| PMC2658783__F2 | The erbB family and the IGF/IGF-1R system |
| PMC2659375__F2 | MET as a target for treatment of chest tumours |
| PMC2659383__F3 | SHH signaling pathway components that have been employed in the production of genetically engineered mouse models |
| PMC2659402__F3 | Interleukin-31 acts through three signaling pathways: Jak/STAT pathway, PI3K/AKT pathway and MAPK pathway |
| PMC2659592__F7 | Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor A2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells |
| PMC2660327__F2 | Network analysis using Ingenuity pathway analysis (IPA) software |
| PMC2660380__F3 | Lysophosphatidic Acid Signaling in Airway Epithelium: Role in Airway Inflammation and Remodeling |
| PMC2660752__F6 | Metabolic origin of glyoxylate in M |
| PMC2660918__F2 | Hypothetical model for the end-joining mechanisms during CSR |
| PMC2661541__F1 | Transforming growth factor-beta (TGFB) signaling pathway |
| PMC2661568__F6 | Schematic model of sequential hippocampal aging changes |
| PMC2661789__F1 | In endothelial cells, after activation, VEGFR2 is able to stimulate the AKT/mTOR signalling pathway through PI3K |
| PMC2661888__F3 | Hypergraph representation of the Boolean model for yeast glucose repression |
| PMC2661962__F1 | Where Do MAIT Cells Fit in the Family of Unconventional T Cells? |
| PMC2662295__F5 | TRAF6- and MEKK1-mediated signal for IFNB production in the RLH/IPS-1 signaling pathway |
| PMC2662368__F2 | T cell differentiation proceeds along distinct pathways following antigen presentation by DCs |
| PMC2662467__F6 | Cell proliferation and apoptosis |
| PMC2662567__F2 | Genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders |
| PMC2662567__F3 | Genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders |
| PMC2662580__F1 | Wnt therapy for bone loss: golden goose or Trojan horse? |
| PMC2662697__F6 | Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88 Dependent and Independent Signaling and is Reciprocally Modulated by LXR Activation |
| PMC2663056__F3 | Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling. |
| PMC2663056__F4 | Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling |
| PMC2663399__F2 | DNA Damage Tolerance: When It's OK to Make Mistakes |
| PMC2663399__F5 | DNA Damage Tolerance: When It's OK to Make Mistakes |
| PMC2663408__F15 | The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification |
| PMC2663527__F1 | The formation of leukotrienes (LTs) through the 5-lipoxygenase pathway of arachidonic acid metabolism, and the effects of LT inhibitors in different contexts |
| PMC2663984__F5 | Expanded canonical Wnt/GSK3 signaling pathway |
| PMC2664745__F1 | Molecular and cellular biology of enhanced cognition |
| PMC2665727__F5 | Ty retrotransposition cycle |
| PMC2665873__F1 | Fatty acid synthesis pathways in C |
| PMC2666018__F12 | Differential Requirement for MEK/ERK and SMAD Signaling in PAI-1 and CTGF Expression in Response to Microtubule Disruption |
| PMC2666381__F1 | TLR signaling and the role of epithelium in corneal innate defense |
| PMC2666387__F7 | Proposed Src involvement in HCEC wound healing |
| PMC2666388__F1 | DHA, NPD1, and BAPP-derived AB peptide signaling circuits in homeostatic aging and in AD |
| PMC2666391__F2 | Toll-Like Receptors and Corneal Innate Immunity |
| PMC2666503__F1 | F igure 1.– |
| PMC2666541__F1 | (panel A) ODC expression is regulated by a number of signaling pathways |
| PMC2666548__F1 | Reactions and proteins of the mitochondrial FAS pathway |
| PMC2666844__F3 | In the absence of Wnt stimulation, the APC (adenomatous polyposis coli) forms a trimeric complex, known as the "destruction complex," with glycogen synthase kinase-3B (GSK) and Axin |
| PMC2666844__F5 | Simplified schematic of hepatocyte growth factor (HGF)/MET signaling pathway |
| PMC2666844__F6 | Simplified schematic diagram of transforming growth factor-alpha/epidermal growth factor receptor signaling pathway (TGFA/EGFR) |
| PMC2667705__F7 | Regulation of hepatic HNF4A expression by insulin: involvement of SREBPs and proposed liver impairments |
| PMC2667750__F8 | Proposed pathway for polyoxin biosynthesis |
| PMC2667788__F3 | Paracrine mechanisms in adult stem cell signaling and therapy |
| PMC2667897__F1 | TGFB superfamily signaling: notes from the desert |
| PMC2667932__F1 | Model for TGFB1-induced PAI-1 expression |
| PMC2667944__F1 | Angiotensin converting enzyme 2 in the brain |
| PMC2667983__F4 | Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern Asia. |
| PMC2668232__F5 | Principles in TLR signaling |
| PMC2668236__F2 | Major pathway and inflammatory mediators of sepsis and its related conditions |
| PMC2668926__F1 | EGFR Signaling Pathway |
| PMC2668982__F2 | CCN1 signaling and crosstalk with TNFA |
| PMC2669301__F1 | Tyrosine kinase network regulating mast cell activation |
| PMC2669548__F1 | Generalized schematic presentation of signaling pathways targeted by molecular therapies in malignant glioma |
| PMC2670002__F7 | Pathway in colorectal cancer (CRC) progression from normal colon to late-stage cancer |
| PMC2670022__F1 | Pharmacological targeting of the serotonergic system for the treatment of obesity |
| PMC2670105__F1 | IMP impedes Ras mitogenic signaling by limiting KSR1 complexes |
| PMC2670521__F9 | New Microbicidal Functions of Tracheal Glands: Defective Anti-Infectious Response to Pseudomonas aeruginosa in Cystic Fibrosis |
| PMC2670612__F2 | Tumor resistance to EGFR-targeted therapies |
| PMC2670830__F4 | Signaling in pterygium |
| PMC2670967__F2 | Schematic (simplified) representation of enzymatic and metabolite components of the liver methionine metabolic pathway, and the influence of ethanol consumption |
| PMC2670969__F4 | PBT-1 induced genes in different pathways according to the KEGG and BIOCARTA pathway databases |
| PMC2671025__F6 | Role of adiponectin in human skeletal muscle bioenergetics |
| PMC2671376__F7 | Signaling in the PI3K/Akt pathway and deregulations detected in GRMD skeletal muscle |
| PMC2671566__F7 | Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor |
| PMC2671631__F1 | The L-arginine biosynthetic pathway and its association to proline and polyamine biosynthesis |
| PMC2671642__F5 | Comprehensive genomic characterization defines human glioblastoma genes and core pathways |
| PMC2671717__F7 | Schematic Overview of Pyrimidine de Novo Synthesis, Salvage, and Degradation.Nucleotides synthesized de novo enter the nucleotide pool and become further converted to nucleic acids and other metabolic intermediates |
| PMC2671802__F1 | ALPS and CEDS illustrate signaling pathways for lymphocyte apoptosis and activation |
| PMC2671916__F6 | Novel functional modules with dynamic gene expression changes potentially linked to prion pathophysiology: (A) androgen metabolism, (B) iron metabolism, (C) arachidonate/phospholipid metabolism |
| PMC2671988__F2 | Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder. |
| PMC2672430__F2 | Prodeath or Prosurvival: Two Facets of Hypoxia Inducible Factor-1 in Perinatal Brain Injury |
| PMC2672935__F2 | Regulated molecules in canonical signalling pathways identified by IPA |
| PMC2673236__F1 | Schematic illustration of one-carbon metabolism pathway |
| PMC2673242__F1 | Loss of PTEN function results in accumulation of PIP3, which activates a cascade of signaling molecules |
| PMC2673422__F6 | Hypoxia-invoked response of the glycolysis gene network |
| PMC2673908__F2 | Unifying model of Wnt signaling with regard to cardiomyogenesis |
| PMC2673912__F6 | Activin Modulates the Transcriptional Response of LBT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation |
| PMC2673912__F8 | Activin Modulates the Transcriptional Response of LBT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation |
| PMC2674015__F2a | Toll-like Receptors: Novel Pharmacological Targets for the Treatment of Neurological Diseases |
| PMC2674123__F10 | Signaling cascade of PI3K/AKT pathway |
| PMC2674225__F2 | Repression of TGFB-RII and abrogated signaling through the Smad pathway |
| PMC2674579__F1 | GST-MDA-7 causes PERK-dependent vacuolization and JNK pathway activation in transformed cells that leads to cell death |
| PMC2674698__F1 | Structures and metabolic pathway of gangliosides () |
| PMC2674702__F1 | Metabolism of extracellular and intracellular bioactive lipids |
| PMC2674738__F1 | Circulating blood monocytes adhere to activated endothelium at sites of disease or injury |
| PMC2674743__F2 | Altered insulin signaling by lipid intermediates |
| PMC2674747__F1 | Illustration of differences in the expression of genes for early steps of sphingolipid metabolism using a KEGG-based microarray analysis tool (GenMapp v2.1) that has been modified to display this pathway more completely (www.sphingomap.org) |
| PMC2674807__F2 | Common polymorphisms in the genes associated with Alzheimer's Disease (AD) |
| PMC2675004__F1 | Crosstalk via the NFKB Signaling System |
| PMC2675030__F3 | Steps in the generation of Th17 cells |
| PMC2675214__F1 | Thymidine biosynthetic pathway |
| PMC2675492__F1 | Biochemical schematics: This figure maybe regarded as the biochemical underpinning of our model |
| PMC2675552__F3 | Mechanism of action of toll-like receptors (TLRs) |
| PMC2675653__F1 | CART analysis of NER pathway and esophageal cancer risk |
| PMC2675709__F5 | Comparison of metabolites and transcripts in glycolysis, tricarboxylic acid (TCA) cycle, and pH-regulating pathways between the wild type (WT) and the stop1 mutant |
| PMC2675987__F1 | Calmodulin-dependent nuclear import and disease |
| PMC2676108__F3 | INHIBITOR OF APOPTOSIS (IAP) PROTEINS IN EUKARYOTIC EVOLUTION AND DEVELOPMENT: A MODEL OF THEMATIC CONSERVATION |
| PMC2676302__F5 | Major trends in mRNA expression at 56 days on experimental diets and summary network analysis among genes |
| PMC2676446__F1 | Regulation of p53 and MDM2 and the outcomes of p53 activation |
| PMC2676714__F4 | Pathways analysis on the set of genes contained in the SNP component |
| PMC2676892__F3 | Chronic Lymphocytic Leukemia and B and T Cells Differ in Their Response to Cyclic Nucleotide Phosphodiesterase Inhibitors |
| PMC2677061__F1 | Postnatal Roles of GDNF Family Members in Nociceptors Plasticity. |
| PMC2677203__F7 | Signaling via the TgfB type I receptor Alk5 in heart development |
| PMC2677387__F1 | mTORC1 activation by nutrients and growth factors |
| PMC2677399__F2 | Nuclear Factor KB, Airway Epithelium, and Asthma |
| PMC2677410__F2 | Novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell |
| PMC2677440__F7 | Rhinovirus-Induced Major Airway Mucin Production Involves a Novel TLR3-EGFR-Dependent Pathway |
| PMC2677552__F3 | PharmGKB pathway diagrams |
| PMC2677763__F7a | Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways |
| PMC2678071__F1 | Graphical representation of the gp130/JAK/STAT pathway |
| PMC2678157__F9 | The steroid synthesis pathway showing genes regulated in this study |
| PMC2678244__F1 | Abl Tyrosine Kinases in T-cell signaling |
| PMC2678718__F1 | Conversion of subendothelial macrophages into cholesterol-laden foam cells is believed to constitute the foundation of the atherosclerotic lesion |
| PMC2678743__F1 | Modifying skin pigmentation - approaches through intrinsic biochemistry and exogenous agents |
| PMC2678983__F4 | IFN-gamma signaling pathway |
| PMC2679052__F7 | Diagram summarizing differences in expression of interaction genes enriched within the KEGG p53 signaling pathway, and possible interactions of corresponding proteins with the androgen receptor |
| PMC2679127__F2 | PRRs and their corresponding ligands |
| PMC2679155__F1 | Integrin-RTK signaling |
| PMC2679172__F1 | Crosstalk at the initial encounter: Interplay between host defense and ameba survival strategies |
| PMC2679302__F2 | Network contains downregulated genes and identified around NFKB gene |
| PMC2679364__F6 | OVARIAN CANCER |
| PMC2679403__F4 | PRO mapping to the Reactome TGF-beta signaling pathway |
| PMC2679427__F1 | Regulation of rat GSTA2 and NQO1 gene expression |
| PMC2679749__F3 | Control of autophagy |
| PMC2679751__F7 | Proposed model for functional interaction between Ncs-1a, Pi4kB, and Arf1 in trafficking and secretion |
| PMC2679770__F3 | Proposed saxitoxin biosynthetic pathway |
| PMC2679904__F1 | TLR mediated signaling |
| PMC2679989__F1 | Function of Nod-like Receptors in Microbial Recognition and Host Defense |
| PMC2680180__F1 | Mitochondria–A Nexus for Aging, Calorie Restriction, and Sirtuins? |
| PMC2680287__F1 | Unraveling the complexities of the interferon response during SARS-CoV infection |
| PMC2680291__F1 | Illustration of some of the key enzymes involved in the metabolism of methotrexate (MTX) |
| PMC2680597__F1 | Methylobacterium Genome Sequences: A Reference Blueprint to Investigate Microbial Metabolism of C1 Compounds from Natural and Industrial Sources |
| PMC2680672__F2 | Regulation mechanisms for Itch-mediated Th2 differentiation.TCR triggering plus CD28-mediated costimulation results in the activation of MEKK1-JNK signaling pathway, which induces the serine/threonine phosphorylation of Itch |
| PMC2681001__F1 | Biosynthetic Pathway of Coenzyme Q10 |
| PMC2681266__F1 | NFKB activation in cancer |
| PMC2681728__F8 | Proposed model of the role of p47 in E |
| PMC2682019__F9 | A link between glucose and insulin signaling in Beta-cells |
| PMC2682028__F9 | Changes in metabolism in Prx1-Cre; PORlox/lox limb bud cells and levels of cholesterol |
| PMC2682038__F8 | An integrated model for the function of TopBP1 in the normal cell cycle and in cancer cells |
| PMC2682371__F2 | ErbB proteins are type I transmembrane receptor tyrosine kinases |
| PMC2682514__F1 | Nodes with the highest relative betweenness centrality (in orange) and their interacting partners (blue) in the pancreatic cancer pathway |
| PMC2682636__F4 | The comorbidity of HIV-associated neurocognitive disorders and Alzheimer's disease: a foreseeable medical challenge in post-HAART era |
| PMC2683106__F5 | Promoting cell proliferation and repressing differentiation |
| PMC2683291__F4 | Mammalian target of rapamycin (mTOR) signalling cascade |
| PMC2683382__F2 | Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites |
| PMC2683584__F1 | Control of Cell Number in the Sexually Dimorphic Brain and Spinal Cord |
| PMC2683622__F9 | Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway |
| PMC2683667__F4 | Induction of IFN-signaling pathways in HCV-infected uPA-SCID mice (A) and patients (B) |
| PMC2683723__F6 | Insulin-EGF signal integration |
| PMC2683725__F3 | A subnetwork that illustrates the effect of homocystinuria on the metabolism and transport of methionine |
| PMC2683871__F6 | p53-regulated pathway analysis using the Ingenuity Pathway Knowledge Base (IPKB) |
| PMC2684021__F1 | The fungal cell wall and downstream cellular responses following engagement of Dectin-1 and TLRs on antigen presenting cells (APC) |
| PMC2684140__F7 | The HIPPO (hpo)-Large tumor suppressor (Lats) pathway validated in Drosophila melanogaster and its similar pathway recently postulated in mammals |
| PMC2684140__F9 | Schematic representation of the S |
| PMC2684502__F2 | CLR-based networks of genes whose expression changed significantly due to aminoglycoside (gentamicin or kanamycin) treatment |
| PMC2684527__F2 | Stochasticity in Protein Levels Drives Colinearity of Gene Order in Metabolic Operons of Escherichia coli |
| PMC2684550__F2 | In MSTN-null mice, regulators of the PI3K pathway and cell survival/apoptosis likely contribute to muscle hypertrophy |
| PMC2684656__F1 | Diagrammatic representation of the signalling pathways activated in the unfolded protein response following ER stress |
| PMC2684849__F3 | Transcriptional regulation of human small nuclear RNA genes |
| PMC2684867__F1 | VHL Loss of Function and Its Impact on Oncogenic Signaling Networks in Clear Cell Renal Cell Carcinoma |
| PMC2685460__F7 | Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae |
| PMC2685579__F1 | Synthetic pathways for polar lipids |
| PMC2685661__F10 | NO/cGMP and calcium signaling in osteoblast mechanotransduction |
| PMC2685877__F1 | Combined Yeast-derived Beta-Glucan with Anti-tumor Monoclonal Antibody for Cancer Immunotherapy. |
| PMC2685917__F9 | Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells |
| PMC2685981__F1 | Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis |
| PMC2685981__F3 | Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis |
| PMC2686112__F1 | VHL gene complex targets hypoxia-inducible factors (HIF) for ubiquitin-mediated degradation |
| PMC2686461__F1 | BCR signaling pathway |
| PMC2686679__F12 | Signaling pathway leading to Egr-1 biosynthesis in thrombin or carbachol-stimulated 39M1-81 cells |
| PMC2686735__F5 | Map of BCR-pathway |
| PMC2687355__F7 | The signaling pathway MyD88 ‡’ p38 ‡’ EGR-1/AP-1 is essential for GBS-induced transcriptional activation of TNF |
| PMC2688381__F4 | Azithromycin Treatment Alters Gene Expression in Inflammatory, Lipid Metabolism, and Cell Cycle Pathways in Well-Differentiated Human Airway Epithelia |
| PMC2688657__F1 | Antigrowth signaling pathway and cluster around SMAD proteins |
| PMC2688657__F3 | Apoptosis pathway |
| PMC2688657__F5 | Growth signal pathway |
| PMC2688747__F4 | Fgf and Sdf-1 Pathways Interact during Zebrafish Fin Regeneration |
| PMC2688755__F2 | Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen |
| PMC2688935__F3 | Networks used to generate simulated data |
| PMC2689134__F4 | Pathogenesis of holoprosencephaly |
| PMC2689231__F6 | Purine biosynthetic pathway, showing protein abundance changes for the P |
| PMC2689781__F7 | Grade-dependent Proteomics Characterization of Kidney Cancer |
| PMC2690004__F3 | Metabolic reconstruction of H |
| PMC2690232__F6 | Conserved Toll-proximal signaling mechanism |
| PMC2690394__F2 | Molecular targets of natural chemopreventive agents |
| PMC2690586__F1 | Maintenance of the G1/S DNA damage checkpoint in the presence and absence of Cdk2 |
| PMC2690992__F2 | Signaling control of mesenchymal and amoeboid cell phenotypes |
| PMC2691147__F1 | Hh signalling–a simplified model |
| PMC2691592__F7 | Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-Induced Apoptosis |
| PMC2691779__F1 | Schematic overview of the human tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) apoptosis pathway |
| PMC2691965__F2 | Toll-like receptor (TLR) activation |
| PMC2692221__F1 | BER subpathways for damaged bases and DNA strand breaks |
| PMC2692251__F2 | HuR and/or AUF1 differentially regulate mRNAs encoding cell cycle and Erk1/Erk2 Mapk signaling-related genes in MCT-1-transformed cells |
| PMC2692400__F1 | Hormone and nutrient signaling pathways modulating leptin translation |
| PMC2692402__F1 | Glycerol phosphate pathway for de novo triacylglycerol (TAG) and glycerophospholipid synthesis |
| PMC2692634__F1 | THE ENZYMES OF THE 10-FORMYL-TETRAHYDROFOLATE SYNTHETIC PATHWAY ARE FOUND EXCLUSIVELY IN THE CYTOSOL OF THE TRYPANOSOMATID PARASITE LEISHMANIA MAJOR |
| PMC2692823__F2 | Hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem |
| PMC2693146__F8 | Model depicting the dual role of cGKI in BMP signalling pathway cGKI regulates BMP signalling through (light blue) modulation of BMP receptors at the cell surface and enhancement of R-Smad phosphorylation and thus Smad activation |
| PMC2693232__F2 | Unifying model of TGFB signaling in breast epithelium |
| PMC2693384__F2 | Regulation of Vascular Permeability by Sphingosine 1-Phosphate |
| PMC2693450__F3 | Lipodystrophies: Disorders of adipose tissue biology |
| PMC2694412__F6 | Somatic mutations affect key pathways in lung adenocarcinoma |
| PMC2694443__F8 | BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway |
| PMC2694487__F5 | Human presenilin 1 and 2 (PSEN1 and PSEN2) subnetworks |
| PMC2694580__F2 | Biological actions of isoprenoids |
| PMC2694616__F1 | Genomic Strategy to Elucidate Modules of Oncogenic Pathway Signaling Networks |
| PMC2694804__F2 | Summary of the pathways transduced by the primary cilium |
| PMC2694962__F1 | Schematic illustration of overview of one-carbon metabolism pathway, linking to methylation reactions and nucleotide synthesis |
| PMC26952__F7 | Activation of specific target genes by TGFB and Wnt pathways |
| PMC2695202__F2 | Emerging anti-inflammatory therapy |
| PMC2695499__F10 | Changes in OSM signaling |
| PMC2695762__F2 | Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity |
| PMC2695822__F10 | Display of genes with high expression in CT embryos |
| PMC2695822__F9 | Display of genes with high expression in IVF embryos |
| PMC2695826__F1 | Ingenuity pathway analysis identified a network of genes down regulated in response to 60 minutes of ischemia in aged mouse liver |
| PMC2695826__F2 | Age-Related Decrease in Proteasome Expression Contributes to Defective NFKB Activation during Hepatic Ischemia/Reperfusion |
| PMC2695927__F4 | Bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease |
| PMC2696125__F2 | Docosanoids are multifunctional regulators of neural cell integrity and fate: significance in aging and disease |
| PMC2696130__F3 | Liquid Movement Across the Surface Epithelium of Large Airways |
| PMC2696130__F4 | Liquid Movement Across the Surface Epithelium of Large Airways |
| PMC2696288__F7 | Protein Acetylation Microarray Reveals NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis |
| PMC2696318__F1 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F2 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F3 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F4 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F5 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F6 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F7 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696319__F1 | Sites of mutation which can result in activation of the Raf>MEK>ERK pathway |
| PMC2696328__F5 | Proposed model for the effect of HPTE in the granulosa cell |
| PMC2696359__F1 | TNF-Induced MAP Kinase Activation Oscillates in Time |
| PMC2696553__F1 | Store-operated Ca2+ entry in T cells |
| PMC2696566__F1 | Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy |
| PMC2696566__F2 | Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy |
| PMC2696814__F1 | Autophagy in the Pathogenesis of Disease |
| PMC2697061__F2 | Endoplasmic reticulum stress in disorders of myelinating cells |
| PMC2697172__F8 | Sub-network associated with the Wnt signaling pathway |
| PMC2697290__F1 | Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart |
| PMC2697617__F1 | Live Longer Sans the AT1A Receptor |
| PMC2697619__F5 | Proposed signaling pathways by which the Tec kinases regulate JNK activation, actin polymerization, and cytokine expression in LPS-stimulated neutrophils |
| PMC2697824__F3 | Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: A review |
| PMC2698322__F3 | Complex relationship between PI3-K, mTOR and PKB signalling |
| PMC2698322__F4 | Key proteins regulated by PKB that are involved in metabolism (yellow); cell cycle progression (green); cellular growth (red); cell survival and apoptosis (blue); angiogenesis (orange) and neurological processes (purple) |
| PMC26984__F1 | Proposed pathway of EGF-induced cell proliferation of ER- breast cancer cells |
| PMC2698574__F9 | The VACV- and CPXV-stimulated PI3K/Akt pathway of biological relevance in spontaneously immortalized A31 and MEF cells |
| PMC2698645__F1 | Simplified schematic representation of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway driven by muscle contraction, insulin, essential amino acids (leucine), and/or energy |
| PMC2698645__F2 | Simplified schematic representation of the interaction between the mTORC1 and ERK1/2 signaling pathways following muscle contraction and/or insulin stimulation |
| PMC2698768__F9 | Model of CD28 signaling pathways initiated by the distal and proximal motifs |
| PMC2698936__F2 | Integrins in Lens Development and Disease |
| PMC2699281__F2 | Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease |
| PMC2699281__F3 | Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease |
| PMC2699361__F1 | The ER-mitochondria apoptotic signalling pathway operating in cells devoid of mitochondrial BAK and BAX, and of ER-located BAX |
| PMC2699768__F3 | Aryl hydrocarbon receptor (AhR) pathway as a regulatory pathway for cell adhesion and matrix metabolism |
| PMC2699853__F1 | Diabetes alters the expression of multiple genes of the TGFB pathway (left side of the panel) and BMPs pathway (right side) in rat retinal vessels |
| PMC2699904__F7 | Inter-relationships of genes associated with apoptosis differentially expressed in the lacrimal glands of C57BL/6.NOD-Aec1Aec2 mice |
| PMC2699904__F8 | Schematic showing inter-relationships of clustered genes associated with fatty acid, lipid and lipoprotein homeostasis based on differentially-expressed genes identified in lacrimal glands of C57BL/6.NOD-Aec1Aec2 mice |
| PMC2699967__F2 | Signaling pathways initiated by TLR-2 and TLR-4 activation |
| PMC270001__F2 | Chemoresistance in Human Ovarian Cancer Cells |
| PMC2700035__F6 | Load-driven signaling pathways predicted with ankle loading at 1 h after the last loading |
| PMC2700095__F10 | Alternative kinetic model incorporating unknown transcription factor (TFx) activation by Eda/Edar signaling |
| PMC2700213__F1 | Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians |
| PMC2700405__F1 | The canonical Wnt/Beta-catenin signaling pathway |
| PMC2700428__F2 | Some cellular processes implicated in the pathogenesis of PAH |
| PMC2701191__F4 | Regulation of cell junction dynamics by cytokines in the testis - a molecular and biochemical perspective |
| PMC2701885__F2 | Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence |
| PMC2702150__F3 | FIBROTIC DISEASE AND THE TH1/TH2 PARADIGM |
| PMC2702319__F4 | Distributions of the orthologous gene groups containing duplicate genes that arose through 3R-WGD (shown as gray boxes) in the network diagrams |
| PMC2702500__F1 | Metabolic reconstruction of Db |
| PMC2702690__F9 | Molecular Mechanisms of HIF-1A Modulation Induced by Oxygen Tension and BMP2 in Glioblastoma Derived Cells |
| PMC2702844__F2 | Cell biology of autophagy in metazoans: a developing story |
| PMC2703803__F1 | The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target |
| PMC2703816__F3 | Identification of neuronal target genes for CCAAT/Enhancer Binding Proteins. |
| PMC2704234__F3 | Immune activation induced by Beta-glucans |
| PMC2704251__F1 | Porphyromonas gingivalis-Host Interactions: Open War or Intelligent Guerilla Tactics? |
| PMC2704458__F2 | Histone Acetylation in Drug Addiction |
| PMC2704469__F8 | Scheme indicating expression of Tcf4 proteins and effects of Wnt-Beta-catenin signaling to inhibit the transition from premyelinating to mature oligodendrocyte |
| PMC2704571__F2 | Diagrammatic representation of hormone therapy-induced changes in gene expression in the dorsal raphe block |
| PMC2704572__F1 | Complement effectors generated during activation contribute to various mechanisms that limit tumor growth |
| PMC2704572__F2 | Some complement proteins can accelerate tumor growth |
| PMC2704867__F5 | Darpp-32 and Its Truncated Variant t-Darpp Have Antagonistic Effects on Breast Cancer Cell Growth and Herceptin Resistance |
| PMC2705117__F3 | Role of peroxisome-proliferator-activated receptor B/D (PPARB/D) in gastrointestinal tract function and disease |
| PMC2705893__F1 | Protein kinase Cι: human oncogene, prognostic marker and therapeutic target |
| PMC2705999__F3 | Castration-Adapted Prostate Cancer: Targeting Androgen Metabolic Pathways in Recurrent Disease |
| PMC2706143__F2 | The Endoplasmic Reticulum and the Unfolded Protein Response |
| PMC2706143__F3 | Endoplasmic Reticulum and the Unfolded Protein Response |
| PMC2706303__F2 | Bioelectric mechanisms in regeneration: unique aspects and future perspectives |
| PMC2706609__F1 | ERK1/2 pathway in airway epithelial cell responses to cigarette smoke |
| PMC2707240__F2 | Proposed model for As2O3-dependent activation of the mTOR pathway in a negative feedback regulatory manner in malignant cells |
| PMC2707261__F1 | Regulation of glycolysis, glutaminolysis and de novo nucleotide biosynthesis in tumor cells |
| PMC2707271__F5 | Proposed mechanism for MAP4K3 cell death signaling |
| PMC2707344__F4 | Metabolic implication of leaf mitochondria during water stress |
| PMC2707511__F6 | DNA Topoisomerase I Inhibitors: Chemistry, Biology and Interfacial Inhibition |
| PMC2707763__F6 | PROK1 induction of RCAN1-4 and IL-8 |
| PMC2707780__F1 | Model of the role of MAPK cascades in cardiomyocyte hypertrophy |
| PMC2708714__F2 | Direct targets of WT1 identified in the Wnt signaling pathway |
| PMC2708980__F8 | Proposed signaling pathway |
| PMC2709066__F1 | De novo purine synthesis pathway |
| PMC2709272__F1 | Wnt/Beta-catenin signaling in adipogenesis and metabolism |
| PMC2709380__F7 | Hypothetical model of transcriptional regulation of the p21 gene and p53 pathway |
| PMC2709429__F11 | Production of Superoxide Anions by Keratinocytes Initiates P. acnes-Induced Inflammation of the Skin |
| PMC2709856__F1 | It's all in the family: multiple Toll-like receptors offer promise as novel therapeutic targets for stroke neuroprotection |
| PMC2710138__F2 | Phosphatidylinositol 3–kinase (PI3K) signaling pathway |
| PMC2710138__F8 | Feedback inhibition of the phosphatidylinositol 3–kinase (PI3K) pathway |
| PMC2710522__F1 | Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data |
| PMC2710681__F4 | Model describing TLS across CPD in human cells |
| PMC2711321__F2 | Wiring diagrams for a three-module decomposition of the intrinsic apoptotic pathway |
| PMC2711664__F1 | Signal transduction mechanisms implicated in leptin action |
| PMC2712099__F2 | The aryl hydrocarbon receptor (AHR) signalling pathway |
| PMC2712453__F2 | G1-phase signaling pathways inferred with different heuristics |
| PMC2712453__F3 | S-phase signaling pathways inferred with different heuristics |
| PMC2712453__F5 | Erb-associated signaling pathways |
| PMC2712453__F6 | TLR-mediated innate immune signaling pathway |
| PMC2712453__F7 | Signaling pathway inferred from a gene regulatory network |
| PMC2712597__F1 | Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways |
| PMC2712597__F6 | Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways |
| PMC2712626__F1 | The Double Life of Irs |
| PMC2712666__F3 | TNF superfamily: costimulation and clinical applications |
| PMC2712786__F1 | Pathways of extrinsic and intrinsic apoptosis, highlighting roles of Bcl-2 family members |
| PMC2713013__F3 | MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES |
| PMC2713013__F7 | MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES |
| PMC2713245__F1 | Signal transduction through activin receptors |
| PMC2713319__F1 | Apoptosis and Epithelial Injury in the Lungs |
| PMC2713319__F3 | Apoptosis and Epithelial Injury in the Lungs |
| PMC2713330__F1 | Innate Immunity in the Lungs |
| PMC2713346__F1 | Crz1 enters the nucleus in short stochastic bursts lasting about 2 min after undergoing dephosphorylation in the cytoplasm by the calcium-activated phosphatase calcineurin (Cn) (, ) |
| PMC2713381__F8 | MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway |
| PMC2713566__F1 | Mitochondrial pathways of electron flow resulting from the substrates and inhibitors used in this study |
| PMC2713571__F1 | Proposed cuticle pigmentation and sclerotization metabolic pathway in T |
| PMC2713831__F5 | Local Network Topology in Human Protein Interaction Data Predicts Functional Association |
| PMC2714185__F1 | Role of ATM in cellular responses |
| PMC2714185__F3 | Major regulatory steps in the process of DNA damage response (DDR) |
| PMC2714639__F6 | MT1-MMP expression in first trimester trophoblasts is stimulated by insulin, IGF1 and IGF2 by different signalling pathways |
| PMC2714846__F6 | Estradiol-17B, prostaglandin E2 (PGE2) and the prostaglandin E2 receptor are involved in PGE2 positive feedback loop in the porcine endometrium |
| PMC2715000__F8 | Summary of caspase 2-mediated signaling cascades in heat-induced germ cell apoptosis |
| PMC2715236__F6 | Model for the role of FANCM in the DNA damage response |
| PMC2715245__F7 | Comparison of models for FRAXA and APC-inducible chromosome fragility |
| PMC2715501__F1 | Study background |
| PMC2715808__F8 | Regulation of mTORC1 signaling by mTOR S1261 phosphorylation |
| PMC2715810__F7 | Model of PERK pathway controlling rRNA transcription and translation in comparison to mTOR |
| PMC2715958__F1 | One possible pathway which regulates cell proliferation in response to strain on collagen |
| PMC2715958__F2 | One possible pathway which regulates cell migration in response to strain on fibronectin |
| PMC2715971__F2 | Interaction between insulin and interferon-alfa signaling pathway |
| PMC2716072__F4 | mTOR signaling pathway |
| PMC2716493__F1 | Two main pathways involved in apoptosis regulation |
| PMC2716541__F6 | Apoptosis of CD4+CD25high T Cells in Type 1 Diabetes May Be Partially Mediated by IL-2 Deprivation |
| PMC2716750__F1 | Gene regulatory networks in kidney development |
| PMC2716751__F2 | The concept of angiotensin II-growth factor cross-talk in ureteric bud morphogenesis |
| PMC2716793__F3 | Spatial complexity and control of a bacterial cell cycle |
| PMC2716801__F1 | Schematic illustration of the Warburg effect in tumor cells and in early asymptomatic endothelial cell dysfunction |
| PMC2717722__F2 | Blocking the myostatin pathway |
| PMC2717887__F2 | Clusterin as a critical signaling node |
| PMC2718282__F8 | The role of Mal connecting PI3K to TLR2/6 |
| PMC2718437__F2a | Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor B |
| PMC2718437__F4a | Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor B |
| PMC2718491__F3 | Multiple regulatory pathways for N-WASP and WAVE2 activation |
| PMC2718504__F5 | Predicted general metabolism and solute transport in T |
| PMC2718747__F10 | A model of EGF/EGFR-induced inhibition of a Luminal-A phenotype in MCF-7 cells |
| PMC2719108__F2 | Schematic representation of the renin angiotensin system |
| PMC2719424__F8 | DUOX1 involvement in TLR-mediated IL-8 production in response to bacterial stimuli |
| PMC2719559__F2 | Paracrine and autocrine mechanisms of Akt-mediated tumor-stromal interactions |
| PMC2719801__F2 | Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways |
| PMC2719801__F3 | Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways |
| PMC2719943__F1 | Reduced levels of neurotransmitter-degrading enzyme PRCP promote obesity |
| PMC2720031__F1 | GR signal transduction pathway |
| PMC2720036__F1 | Selective Raf Inhibition in Cancer Therapy |
| PMC2720036__F5 | Selective Raf Inhibition in Cancer Therapy. |
| PMC2720065__F8 | Proposed signaling pathway of mmLDL-induced, TLR4/Syk-dependent ROS generation and proinflammatory cytokine expression |
| PMC2720262__F1 | Summary of consequences on signal transduction and brain architecture of conditional Pten or Pdk1 deletion, alone or in combination |
| PMC2720375__F7 | Genome-Wide Screen of Genes Required for Caffeine Tolerance in Fission Yeast |
| PMC2720436__F1 | Hippo pathway, a vital growth regulator of cell proliferation and apoptosis was initially identified by mosaic screens in Drosophila melanogaster (,) |
| PMC2720607__F2 | Principal enzymes and substrates of the folate pathway involved in formation of tetrahydrofolate (THF) and its utilisation in the thymidylate cycle |
| PMC2720726__F1 | IFNB activated pathway |
| PMC2721253__F2 | Modes of neurite growth inhibition of molecules expressed on CNS myelin and oligodendrocytes |
| PMC2721285__F1 | RAS/MAP kinase signaling pathway |
| PMC2721345__F1 | Simplified scheme of the VEGF/VEGFR pathway |
| PMC2721360__F2 | Colorectal cancer cells share the WNT pathway in response to growth suppression by APHS-mediated COX-2 inhibition |
| PMC2721377__F1 | Molecular toll-like receptors (TLRs) of the human gastrointestinal (GI) tract which act as sensors and are the first responders in the major pathway by which the immune system detects infection or damaged tissue |
| PMC2721397__F2 | Key pathways in hepatocarcinogenesis and molecularly targeted agents currently under investigation in treatment of advanced HCC |
| PMC2721475__F1 | Downstream targets of IGF-1R |
| PMC2721684__F1 | Signaling pathways triggered by TLR3, TLR4 and TLR1-TLR2 |
| PMC2721689__F1 | Structural and functional modules in RNA interference |
| PMC2721821__F6 | Graphical representation of the Hh signaling pathway in its activated state and possible sites of HPI action |
| PMC2721971__F3 | EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis†|
| PMC2722023__F4 | Genome-Wide mRNA Expression Analysis of Hepatic Adaptation to High-Fat Diets Reveals Switch from an Inflammatory to Steatotic Transcriptional Program |
| PMC2722148__F1 | MAPK transduction signaling pathway |
| PMC2722219__F1 | The TSC/mTOR signaling pathway |
| PMC2722250__F2 | Silent chromatin assembly in budding and fission yeast |
| PMC2722335__S1 | Adipocyte lineage commitment and terminal differentiation |
| PMC2722767__F3 | Application of SysPTM tools |
| PMC2722780__F8 | Putative BK-BKAP interactions derived from the BK interactome in mouse cochlea |
| PMC2723150__F1 | Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is central for physiological responses to extracellular and intracellular signals |
| PMC2723760__F4 | HERPUD1 Ingenuity Pathway Analysis illustrates interactions between indicated proteins |
| PMC2723786__F1 | BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells |
| PMC2723817__F1 | Targeting lung inflammation: novel therapies for the treatment of COPD |
| PMC2723867__F1 | Dynamics of Membrane Trafficking Downstream of B and T Cell Receptor Engagement: Impact on Immune Synapses |
| PMC2724002__F2 | Controlling Hair Follicle Signaling Pathways through Polyubiquitination |
| PMC2724029__F4 | Signaling networks upregulated in migrating neuroblasts |
| PMC2724029__F5 | Signaling networks upregulated in migrating neuroblasts |
| PMC2724047__F5 | Major cell signaling pathways activated by bile acids in hepatocytes |
| PMC2724047__F6 | Activation of the Akt (insulin signaling pathway) and FXR by bile acids in hepatocytes |
| PMC2724105__F2 | The postreceptor insulin signaling pathway and insulin-independent 5'-adenosine monophosphate kinase (AMPK) beginning from insulin binding to its receptor to GLUT4 translocation via vesicular trafficking |
| PMC2724271__F4 | Metabolic map of HIF-target genes |
| PMC2724309__F2 | Steroidogenesis pathway: Steroids are in bold; enzymes and cholesterol transport proteins are in italics |
| PMC2724661__F1 | Complement system in AD |
| PMC2724778__F3 | Hypothesis-driven two-factor common pathway model path diagram of the metabolic syndrome |
| PMC2724779__S1 | Complexity of sphingolipid biosynthetic pathways |
| PMC2724780__F1 | Bile acid modulation of death and survival transduction pathways |
| PMC2724989__F1 | Macrophage activation by endogenous danger signals |
| PMC2725207__F3 | Tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1 |
| PMC2725215__F3 | Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage |
| PMC2725405__F6 | Regulation of IFN response genes by TLR3 signaling |
| PMC2725709__F7 | Mechanistic model of unloading-mediated muscle atrophy |
| PMC2725943__F7 | A model of mammalian Hh signaling |
| PMC2725945__F1 | Stabilization, degradation, and activation of the Ci/Gli proteins by the Hh signaling pathway |
| PMC2726710__F2 | Intracellular signaling consequences of calpain-mediated substrate cleavage |
| PMC2726720__F3 | Interplay of TGFB, Wnt/Beta-catenin, Hedgehog, and Notch in stem cell differentiation and tumorigenesis |
| PMC2726781__F1 | Retromer sorting pathway is made up of a coat complex that binds and transports transmembrane receptors between the endosome and the trans-Golgi network (TGN) |
| PMC2726954__F2 | Quest for genetic determinants of human longevity: challenges and insights |
| PMC2727126__F1 | Noteworthy, the inhibition of this pathway through COX-inhibitors leads to induction of apoptosis and tumor growth reduction (Figure ) |
| PMC2727282__F7 | Proposed coloboma mechanism in Lrp6-null eyes and a possible signaling network during early eye development |
| PMC2727431__F1 | Various states of pluripotency |
| PMC2727567__F1 | Unwelcome Complement |
| PMC2727709__F1 | Multiple previously established signaling cascades in activated mast cells with quantitative proteomic data from MCP5 cells represented as heatmap bars beside individual proteins |
| PMC2727866__F1 | EGFR-dependent MAPK activation |
| PMC2727867__F1 | Representation of some zinc-induced apoptotic pathways |
| PMC2727884__F2 | Mechanism of action of sorafenib |
| PMC2727910__F1 | Map of arachidonic acid (AA) cascade |
| PMC2727911__F1 | Activation pathways of the complement system and complement regulatory proteins |
| PMC2727921__F1 | Genetic polymorphisms, their allele combinations and IFNB treatment response in Irish multiple sclerosis patients |
| PMC2728081__F2 | Regulation of B-cell entry into the cell cycle |
| PMC2728144__F6 | Schematic diagram depicting our findings on the post-transcriptional regulation of CXCR4 in MCF7-HER2 cells as a result of estrogen and HER2 cross-talk and the involvement of activated PI3K and MAPK pathways and TSC2 (tuberin) |
| PMC2728430__F1 | How ERK1/2 Activation Controls Cell Proliferation and Cell Death Is Subcellular Localization the Answer? |
| PMC2728746__F7 | Proposed model for the mitogen-activated protein kinase kinase 4 (MEK4) regulation of human prostate cell motility and for its inhibition by genistein |
| PMC2728865__F2 | Transcriptional Regulation of Metabolism Associated With the Increased Desiccation Resistance of the Cactophilic Drosophila mojavensis. |
| PMC2729268__F2 | Map of protein interactivity (binding, regulation, modification) between genes revealed to be significantly associated with bladder cancer in urothelial cell samples |
| PMC2729314__F2 | Wnt signaling network |
| PMC2729321__F3 | Is NFKB a good target for cancer therapy? Hopes and pitfalls |
| PMC2729336__F3 | Transcriptional control of HC and amacrine cell development |
| PMC2729380__F6 | Expression and Functional Studies of Ubiquitin C-Terminal Hydrolase L1 Regulated Genes |
| PMC2729687__F2 | Immunological synapse or the interface between an antigen presenting cell and a T-cell |
| PMC2729812__F1 | Proposed pathway from pressure overload to LV hypertrophy and fibrosis |
| PMC2729932__F2 | ES-EB system has made possible the identification of multipotent progenitors for both hemato-vascular and cardio-vascular derivatives |
| PMC2729995__F1 | Apoptosis and the main anti-apoptotic molecules: Binding of death receptors (Fas, TNF-R, TRAIL-R) to their ligands (Fas-L, TNF, TRAIL) initiates the extrinsic apoptotic pathway |
| PMC2730119__F3 | Scheme showing the role of different signaling pathways in mediating the effect of high K intake on ROMK and BK channels in the CCD |
| PMC2730524__F3 | Translating insights from the cancer genome into clinical practice |
| PMC2730725__F1 | Nm23-H1suppression of tumor metastasis may depend on at least three pathways |
| PMC2730990__F2 | TGFB can leave you breathless |
| PMC2731131__F10 | Schematic summary of LPS-triggered programmed cell death in human endothelial cells |
| PMC2731164__F7 | Embryonic Stem Cell Differentiation |
| PMC2731241__F1 | Modeling Molecular and Cellular Aspects of Human Disease using the Nematode Caenorhabditis elegans |
| PMC2731267__F1 | Some putative molecular mechanisms that underlie the antineoplastic activity of mesalazine |
| PMC2731675__F3 | FOLLICULAR HELPER T CELLS: LINEAGE AND LOCATION |
| PMC2731678__F3 | PAK Signaling in Oncogenesis |
| PMC2731733__F5 | Cytoskeletal Remodeling: FAK Signaling pathway is enriched for HeLa and TOV edge hits using PIPA but not node hits using HGA enrichment |
| PMC2732336__F1 | Outline of the major cell surface receptor-mediated signaling pathways important in the differentiation, survival, and function of melanocytes |
| PMC2732416__F5 | Roles of the ILS pathway and HSF1 in aggregation toxicity and longevity |
| PMC2732569__F2 | The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics |
| PMC2733081__F4 | MAPK Signaling Cascade is a Central Hub in the Regulation of Cell Cycle, Apoptosis and Cytoskeleton Remodeling by Tripeptidyl-Peptidase II |
| PMC2733082__F2 | InterferonG signaling pathway and mutations in its components found in human uterine leiomyosarcoma |
| PMC2733092__F4 | Intersection sets of the differentially expressed miRNAs constitute complex interaction networks.A Venn diagram illustrating the production of intersection sets from three miRNA target prediction algorithms |
| PMC2733244__F2 | Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity |
| PMC2733795__F4 | Regulation of STAT3 signal transduction pathway |
| PMC2733936__F1 | Targeting the ASK1/MKK4/JNK pathway upstream of mitochondrial prodeath signaling |
| PMC2734563__F2 | Possible mechanisms of UbcH7 regulation of Chk1 levels sand S phase |
| PMC2735047__F3 | Graft-versus-Host Disease |
| PMC2735125__F7 | HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Non-Overlapping Mechanisms |
| PMC2735334__F1 | Carcinogenesis of Bcr-Abl in CML |
| PMC2735462__F3 | Ubiquitin in NFKB Signaling |
| PMC2735600__F7 | Contribution of Rho to canonical Wnt3A signaling |
| PMC2735864__F1 | Genetic Variation in TNF and the NFKB Canonical Pathway and Risk of Non-Hodgkin Lymphoma |
| PMC2735908__F8 | Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway |
| PMC2736107__S2 | In addition to the hypothesis outlined in , a number of other mechanistic pathways could potentially lead to the formation of products 3-5 () |
| PMC2736203__F2 | Impact of a mixed microbial challenge on cell cycle control in HIGK |
| PMC2736291__F2 | Diagram shows the cell signaling pathways, which were involved in postconditioning |
| PMC2736328__F2 | Transcriptional regulation of cytokine function in airway smooth muscle cells |
| PMC2736391__F2 | Simplified model of the leptin signaling pathway |
| PMC2737000__F4 | TNF-induced NFKB and apoptosis pathways |
| PMC2737000__F5 | Arachidonic acid metabolism pathway |
| PMC2737000__F6 | Androgen receptor pathway |
| PMC2737093__F6 | Schematic view of PPARG activation in VSMCs |
| PMC2737270__F1 | Autophagy pathway and machinery.A |
| PMC2737513__S1 | IMP Dehydrogenase: Structure, Mechanism and Inhibition |
| PMC2737689__F2 | Multiple isoforms catalyze each step in the glycerol-3-phosphate pathway of TAG synthesis |
| PMC2737697__F2 | Genetic Susceptibility to Lupus: New Insights from fine mapping and genome-wide association studies |
| PMC2737901__F1 | Putative biosynthetic pathway of PUFAs in Mortierella alpina 1S-4 |
| PMC2738133__F3 | Molecular Aspects of Moraxella catarrhalis Pathogenesis |
| PMC2738707__F1 | Regulatory pathways in hepcidin expression |
| PMC2739295__F6 | Gene Expression Profiling in Cells with Enhanced Gamma-Secretase Activity |
| PMC2739389__F2 | Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape |
| PMC2739389__F3 | Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape |
| PMC2739756__F1 | Bile acid synthesis |
| PMC2739756__F3 | FXR regulation of enterohepatic circulation of bile acid |
| PMC2739756__F4 | FXR-independent and bile acid-activated cell signaling pathways in regulation of CYP7A1 transcription |
| PMC2740411__F8 | Transcriptional regulation of cell cycle arrest gene p21 by ZBTB5 |
| PMC2740793__F2 | TGFB signaling pathway |
| PMC2741134__F2 | Inteferons pen the JAK-STAT pathway |
| PMC2741634__F2 | How location governs Toll like receptor signaling |
| PMC2742086__F2 | Functional and structural organization of migratory mesenchymal cells |
| PMC2742089__F3 | A biochemical pathway of secreted proteins that regulate D-V patterning in Xenopus |
| PMC2742090__F4 | Negative feedback loops in the SHH signaling pathway driven by SHH-binding proteins |
| PMC2742468__F1 | Metabolic cooperativity between oocytes and cumulus cells, and the role of oocyte-derived paracrine factors in promoting metabolism in cumulus cells |
| PMC2742584__F7 | Interaction networks of As sensitivity in yeast |
| PMC2742684__F1 | Key signaling pathways between amino acids, inflammatory cytokines, and tumor-specific factors gr1Amino acids stimulate muscle protein synthesis through the mTOR pathway |
| PMC2742785__F8 | Cluster 2 genes significantly overlapped with those in the eicosanoid signaling pathway (P = 4.6E-05) |
| PMC2743116__F1 | Ras/mitogen-activated protein kinase (MAPK) signaling pathway and associated developmental syndromes (indicated by dashed lines) |
| PMC2743144__F1 | mTORC1 signaling governs hematopoietic stem cell quiescence |
| PMC2743241__F1 | Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents |
| PMC2743272__F1 | Mechanisms underlying the pleiotropic effects of statins in stroke |
| PMC2743287__F5 | Time-Resolved Transcriptome Analysis of Bacillus subtilis Responding to Valine, Glutamate, and Glutamine |
| PMC2743399__F3 | Improved readability and performance with multi-scale information integrated in pathway visualization using metagraph |
| PMC2743781__F3 | NAD biosynthetic pathways from nicotinamde and nicotinic acid in yeast, invertebrates, and mammals |
| PMC2743934__F8 | Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD |
| PMC2743935__F5 | Calcium signalling and cell-fate choice in B cells |
| PMC2744278__F3 | Phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling pathways |
| PMC2744356__F1 | Toll-like receptors in skin infectious and inflammatory diseases |
| PMC2744640__F4 | Regulation of Mitochondrial Respiratory Chain Biogenesis by Estrogens/Estrogen Receptors and Physiological, Pathological and Pharmacological Implications |
| PMC2744654__F5 | ProMeTra visualization of relative metabolite pools and transcript abundances during fermentation of the l-lysine producer C |
| PMC2744676__F2 | Diagram depicting proliferative and survival signaling pathways in cells |
| PMC2745153__F2 | Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling |
| PMC2745384__F6 | RCAN1 mediated regulation of cell proliferation and apoptosis: Schematic shows that GC-dependent GR activation and subsequent MAP kinase-dependent phosphorylation enables GR binding to GRE sequences on target genes |
| PMC2745765__F3 | Linking the MGI and MouseCyc databases |
| PMC2745891__F6 | Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mTOR activity and p27Kip1 localization |
| PMC2746202__F1 | Pathway from PI3K to TOR |
| PMC2746238__F2 | Induction of autoimmunity by pristane and other naturally-occurring hydrocarbons |
| PMC2746245__F2 | Toll-like receptor (TLR) pathway |
| PMC2746245__F6 | Injury-induced changes in the nociceptive pathway |
| PMC2746247__F1 | Pathway Engineered Enzymatic de novo Purine Nucleotide Synthesis |
| PMC2746747__F1 | Molecular ablation of TGFB signaling pathways by tyrosine kinase inhibition: The coming of a promising new era in the treatment of tissue fibrosis |
| PMC2746948__F1 | Apoptosis pathway |
| PMC2747008__F12 | Induction of IFNB and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7 |
| PMC2747034__F1 | MTDH/AEG-1 promotes tumor progression through the integration of multiple signaling pathways |
| PMC2747168__F1 | Acp-group transfer catalyzed by PhTYW2 |
| PMC2747343__F1 | Ingenuity pathway analysis shows 17 genes from the 180 genes associated with the NF-E2-related factor-2 (NRF-2)-mediated oxidative stress response pathway |
| PMC2747759__F1 | Monoclonal antibodies in the treatment of pancreatic cancer |
| PMC2747760__F1 | Leptin signaling: A key pathway in immune responses |
| PMC2748726__F1 | Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas |
| PMC2748802__F18 | Hypothesized descending pathway for translating emotional states or appetitive need for food, salt or water into goal-directed motor tasks |
| PMC2749258__F3 | Approaches to biomarkers in human colorectal cancer |
| PMC2749259__F2 | Hypothetical diagram of possible sites of action of non-opioids in the regulatory pathway of IL-6 |
| PMC2749270__F1 | Sphingosine-1-phosphate synthesis and functions in mast cells |
| PMC2749448__F1 | Transcriptional Regulation of Carbohydrate Metabolism in the Human Pathogen Candida albicans |
| PMC2749675__F1 | Scheme of the Wnt signaling pathway |
| PMC2749695__F4 | Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target |
| PMC2749695__F5 | Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target |
| PMC2749725__F1 | Coverage of the insulin receptor signaling pathway |
| PMC2749862__F5 | Most prominently affected gene network in response to DEX in TM 86 cells |
| PMC2749862__F6 | Most prominently affected gene network in response to FA in TM 93 cells |
| PMC2750148__F2 | NFKB signal transduction |
| PMC2751538__F7 | Proposed VEGF-C/D cell signaling pathway to transduce LAM cell proliferation |
| PMC2751658__F1 | Diagrammatic representation of intracellular pathways of receptor-mediated endocytosis and trafficking: The ligand binding to specific cell surface receptor leads to a selective recruitment of ligand-receptor complexes into clathrin-coated pits |
| PMC2751986__F7 | Rev-erbA/PGC-1A pathway regulating heme homeostasis |
| PMC2751999__F6 | LPA effect and signal transduction pathway |
| PMC2752022__F3 | Akt-FoxO pathway in regulation of heart size |
| PMC2752361__F3 | MOLECULAR CONSTITUTION OF BREAST BUT NOT OTHER REPRODUCTIVE TISSUES IS RICH IN GROWTH PROMOTING MOLECULES |
| PMC2752373__F1 | Selected transformation pathways of tamoxifen and the main CYP enzymes involved |
| PMC2752535__F4 | Common features of host-Flaviviridae interactions |
| PMC2752832__F7 | Scheme for up-regulation of the PAI-1 gene by EGF in glioblastoma |
| PMC2752847__F1 | Type I interferon production by dendritic cells in host defense |
| PMC2753670__F3 | Integration of ITAM and cytokine Jak-STAT signaling |
| PMC2753833__F4 | Transition to endocycles in Drosophila |
| PMC2753863__F1 | Examination of Association of Genes in the Serotonin System to Autism |
| PMC2754046__F1 | Hypothetical schematic of a DAergic synapse |
| PMC2754156__F3 | LPS signal transduction via the MyD88-dependent pathway |
| PMC2754156__F4 | LPS signal transduction via the MyD88-independent pathway |
| PMC275444__F7 | Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility |
| PMC2754444__F5 | T-Cell Activation Pathways Generated by HIV-Modulated Proteins |
| PMC2754479__F4 | Genomic position of the FGFRL1, FGF8/17/18 and FGFR orthologues in several metazoan species |
| PMC2754507__F1 | Hypothetical view of the pathogenic effects of IL-15 and IL-21 in celiac disease |
| PMC2754694__F1 | Transcriptional regulation of human CYP17 |
| PMC2754696__F1 | CIE and CDE pathways showing lipid content and regulatory molecules |
| PMC2754915__F1 | Schematic illustration of different pathways of glucose metabolism in cancer cells |
| PMC2754915__F3 | Signalling events which determine glucose utilization within the cell |
| PMC2754932__F6 | Model of Udu function in DNA damage response |
| PMC2755046__F1 | Adiponectin-mediated regulation of inflammatory responses in different cell types |
| PMC2755611__F1 | Regulation of aging: does autophagy underlie longevity? |
| PMC2755790__F1 | Network analysis of differentially expressed proteins (red symbols) involved in arteriogenesis |
| PMC2756021__F3 | Neuroprotective Effects of the Complement Terminal Pathway During Demyelination: Implications for Oligodendrocyte Survival |
| PMC2756045__F2 | LKB1-AMPK pathway: metabolism and growth control in tumor suppression |
| PMC2756045__F3 | LKB1-AMPK pathway: metabolism and growth control in tumor suppression |
| PMC2756045__F4 | LKB1-AMPK pathway: metabolism and growth control in tumor suppression |
| PMC2756058__F1 | Pathway of cellular processing of cobalamin (OH-cbl) and location of main enzyme defects in the pathway leading to methylmalonic acidemias and cobalamin metabolic disorders |
| PMC2756316__F5 | Proposed model for the interaction between PyVmT and IR or IGF-IR |
| PMC2756331__F1 | Trk receptor tyrosine kinases and major signal transduction pathways |
| PMC2756474__F7 | CREB Mediates Prostaglandin F2Alpha-Induced MUC5AC Overexpression |
| PMC2756491__F8 | PPARA/p16INK4a Pathway inhibits Vascular Smooth Muscle Cell Proliferation by repressing Cell Cycle-dependent Telomerase Activation |
| PMC2756670__F3 | Potential mechanisms of estrogen-mediated signaling through estrogen receptor (ESR) and G protein-coupled receptor 30 (GPR30) |
| PMC2756670__F4 | The proposed model underlying the potential lithogenic mechanisms of estrogen through the estrogen receptor 1 (ESR1) pathway in the liver |
| PMC2756763__F1 | Aromatase: synthesis of estrogen in postmenopausal women and its inhibition by aromatase inhibitors |
| PMC2756767__F2 | Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer |
| PMC2756767__F3 | Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer |
| PMC2756960__F8 | Effect of DLK1 and RTL1 but Not MEG3 or MEG8 on Muscle Gene Expression in Callipyge Lambs |
| PMC2757047__F3 | Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity |
| PMC2757120__F1 | Canonical PI3K signaling pathway |
| PMC2757135__F1 | Cholesterol transport in steroid biosynthesis: Role of protein-protein interactions and implications in disease states |
| PMC2757227__F1 | Regulation of ENaC and CFTR by SGK1/Nedd4-2 |
| PMC2757291__F6 | The SLAM-Associated Protein (SAP)/Fyn/PKCθ Pathway is Required for Thymocyte-mediated CD4 T Cell Development |
| PMC2757293__F2 | Innate immune evasion by hepatitis C virus and West Nile virus |
| PMC2757549__F6 | Diagram depicting the inhibitory and activating effects of OSU-A9 on the Akt-NFKB signaling axis and stress response signaling, respectively |
| PMC2757632__F1 | O-GlcNAc cycling: Implications for Neurodegenerative disorders |
| PMC2757648__F3 | Interferon response genes are coordinately upregulated relative to the rs17445836[G] allele of IRF8 |
| PMC2757699__F1 | Metabolic fate of the 13C-label from [1-13C]-glucose |
| PMC2757940__F2 | Major components of FGF and HH signaling pathways |
| PMC2757955__F10 | Proposed model of IGFBP-3 modulation of growth factor receptor activation mediated by S1P |
| PMC2758290__F1 | The SIAE (sialic acid acetylesterase)-Siglec pathway for inhibitory signaling |
| PMC2758293__F2 | An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: A biochemical and molecular perspective |
| PMC2758485__F1 | Wnt/PCP signaling and its effects on organogenesis |
| PMC2758554__F3 | Deacetylases and NFKB in Redox Regulation of Cigarette Smoke induced Lung Inflammation: Implications in Pathogenesis of COPD |
| PMC2758611__F6 | Schematic presentation of the proposed TGFB signaling alteration that promotes HNSCC in mice |
| PMC2758708__F2 | Diagrammatic representation of non-canonical Wnt signalling in a mammalian cell |
| PMC2759052__F1 | Signal transduction pathway mediated by epidermal growth factor receptor (EGFR) |
| PMC2759143__F3 | Different signaling pathway mediated by A3(IV)NC1 |
| PMC2759144__F4 | Model depicting the E2Fs-FA/BRCA axis in the control of cell fate |
| PMC2759177__F3 | Survival signals generated by PI3K and PLD that target mTOR |
| PMC2759942__F5 | Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity. |
| PMC2759974__F1 | MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer |
| PMC2760069__F1 | Brothers and Sisters: Molecular insights into arterial-venous heterogeneity |
| PMC2760340__F2 | Representation of NF1 interactions with the Ras and PI3K pathways |
| PMC2760836__F2 | New concepts in herpes simplex virus vaccine development: notes from the battlefield |
| PMC2760938__F13 | Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase CD, Lyn Kinase, and Matrix Metalloproteinases |
| PMC2761008__F2 | Minimum spanning tree of the network associated with cancer pathway genes |
| PMC2761008__F3 | Cliques or near cliques from the cancer pathway related network Gp |
| PMC2761106__F8 | BMP7 signaling in the NZ |
| PMC2761108__F8 | Roles of BMP signaling pathways during SNS development |
| PMC2761115__F2 | Gonad function and sexual differentiation |
| PMC2761207__F1 | Major pathway of the conversion of propionyl-CoA into succinyl-CoA in human cells |
| PMC2762009__F1 | The Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders |
| PMC2762102__F5 | Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis |
| PMC2762604__F11 | Proteomic and Phospho-Proteomic Profile of Human Platelets in Basal, Resting State: Insights into Integrin Signaling |
| PMC2762706__F3 | Hypoxia signaling pathway in DM patients 4d post-CPB/C |
| PMC2762943__F1 | Epidermal growth factor receptor (EGFR) pathway |
| PMC2762943__F3 | P53 pathway |
| PMC2763047__F2 | The Fibroblast Growth Factor Receptor Signaling Pathway in Non-Small Cell Lung Cancer. |
| PMC2763047__F3 | Fibroblast Growth Factor Receptor Signaling Pathway as a Mediator of Intrinsic Resistance to EGFR-specific Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer |
| PMC2763495__F1 | Metabolic pathways of growth and proliferation |
| PMC2763495__F4 | AMPK-p53 pathway in metabolic adaptation |
| PMC2763507__F1 | Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses |
| PMC2763943__F2 | Nox proteins in signal transduction |
| PMC2764313__F1 | Running on empty: how p53 controls INS/IGF signaling and affects lifespan |
| PMC2764428__F4 | MiRNA/TF-mediated regulatory pathway associated with tumorigenesis |
| PMC2764635__F1 | The EGF activated ERK pathway: This is a schematic of the EGF activated ERK pathway beginning at the level of EGF binding to EGFR and finishing at the level of ERK; see the text for more details on the features and functions of the pathway |
| PMC2764635__F3 | New model of EGF activated ERK pathway: This is a schematic of our new model of the EGF activated ERK pathway which was developed from the original [] EGF model |
| PMC2764635__F7 | Experimental results of Rap1 pathway knockout from Falco et al |
| PMC2764635__F8 | Comparison of growth factor receptor signalling: This figure shows a comparison of ERK signalling from the EGF and Insulin receptors |
| PMC2765277__F3 | Scheme of part of the central metabolism of E |
| PMC2765277__F4 | Alternative pathways in the central metabolism of E |
| PMC2765277__F5 | Amino acid producing elementary flux patterns |
| PMC2765277__F6 | Elementary flux pattern belonging to an aspartate-producing pathway |
| PMC2766052__F8 | The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation |
| PMC2766659__F4 | Signaling molecules and pathways regulating the fate of spermatogonial stem cells |
| PMC2766677__F7 | Proposed scheme of the signaling pathway leading to immature dendritic cell chemotaxis upon exposure to M-tropic gp120 |
| PMC2766863__F2 | Signalling crosstalk in B cells: managing worth and need |
| PMC2766922__F2 | Signaling pathways downstream of HVEM, LIGHT, and their binding partners are shown |
| PMC2767105__F2 | Intracellular ascorbate (Asc) modulates redox-sensitive signaling pathways in microvascular endothelial cells during sepsis |
| PMC2768039__F2 | Genetic Basis for Kidney Cancer. |
| PMC2768486__F10 | Possible mechanism by which BMPs and estrogen regulate GNRH production by GT1-7 cells |
| PMC2768529__F8 | Proposed interplay between IL-15 and TNFA signaling in skeletal muscle |
| PMC2768581__F2 | Role of Cross Talk between PI3-Kinase and ERK/MAP Kinase Pathways in Artery-Vein Specification |
| PMC2768836__F1 | Role of clathrin adaptor proteins in melanosome biogenesis |
| PMC2768990__F2 | BANs of differentially expressed genes in common between cell lines |
| PMC2768997__F1 | Human protein-protein interaction network of aging-associated genes |
| PMC2769052__F9 | Schematic representation of a potential mechanism of IFN-Gamma- and STAT3-dependent cell growth modulated by TSC2/mTOR signaling pathway |
| PMC2769196__F4 | Acromegaly pathogenesis and treatment |
| PMC2769198__F2 | Smad4: gatekeeper gene in head and neck squamous cell carcinoma |
| PMC2769199__F8 | Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice |
| PMC2769250__F3a | Trafficking of Heme and Porphyrins in Metazoa |
| PMC2769253__F3 | MicroRNAs in cancer |
| PMC2769253__F4 | MicroRNAs in cancer |
| PMC2770326__F2 | Mammalian sialic acid metabolism |
| PMC2770326__F4 | Pathway options for sialic acid glycoengineering |
| PMC2770326__F6 | Selective pathway utilization of analogs is ensured by the nonpermissivity of enzymes at critical junctures |
| PMC2770887__F1 | ER stress-induced signaling pathways that mediate autophagy |
| PMC2770888__F2 | Targeting EGFR resistance networks in Head and Neck Cancer |
| PMC2771153__F9 | Schematic presentation of a model of induction of beta cell apoptosis during viral infections |
| PMC2771222__F1 | Recent reports have suggested that the Hedgehog (Hh) pathway is activated in lesional psoriatic skin (; ; ; ), and that pharmacological inhibition of this pathway using cyclopamine may lead to rapid resolution of the disease (; ; ) |
| PMC2771360__F4 | Microglia Are Mediators of Borrelia burgdorferi-Induced Apoptosis in SH-SY5Y Neuronal Cells |
| PMC2771724__F3 | Dopamine Receptor Signaling: Genes differentially expressed in the NAC of LE vs |
| PMC2771724__F4 | Synaptic Long-Term Potentiation: Genes differentially expressed in the NAC of LE vs |
| PMC2772137__F4 | Temporal Profiling of Rat Transcriptomes in Retinol-Replenished Vitamin A-Deficient Testis |
| PMC2772702__F6 | The PI3k/Akt signaling pathway depicting the possible sites of action by the PI3k inhibitors LY294002 and wortmannin and the Akt inhibitors Akt-VIII, Akt-V, and Akt-IV |
| PMC2772826__F1 | Apoptosis in animal models of virus-induced disease |
| PMC2772998__F3 | Gemfibrozil, stretching arms beyond lipid lowering |
| PMC2773007__F8 | Integration of the Beta-Catenin-Dependent Wnt Pathway with Integrin Signaling through the Adaptor Molecule Grb2 |
| PMC2773299__F2 | Schematic representations of the activated RAS-MAPK, RASSF1A/NORE1A, and Dab2IP/ASK1 pathways, iNOS signalling, and FOXM1-related pathways involved in the dysregulation of cell growth and apoptosis in HCC |
| PMC2773416__F6 | Diagrammatic representation of intracellular pathways that lead to the production of IL-12p40 and the mechanisms of azithromycin (AZM) to inhibit the expression of IL-12p40 upon the stimulation of LPS/IFNG |
| PMC2773630__F6 | Molecular interactions during pheromone induced cell polarization |
| PMC2773638__F4 | Coordination of extracellular and intracellular signaling regulates cytoskeletal dynamics and axon formation |
| PMC2773646__F1 | Nodal signaling pathway |
| PMC2773711__F1 | Canonical TCR signaling pathway |
| PMC2773833__F3 | Drivers of senescence and therapeutic opportunities in WS and HGPs |
| PMC2773962__F6 | Model of Tbx2 function for the EC formation in the AVC |
| PMC2774072__F7 | Proposed consequences of impaired insulin signaling in AD brain and in the STZ-injected rat brain |
| PMC2774076__F7 | Current working model of the signaling pathway components (shaded areas) that are differentially regulated in C57 and CD-1 pup brain tissues and cultured NSCs under normoxic and hypoxic (Hx) conditions |
| PMC2774487__F2 | Pathway showing genes involved in Parkinson's disease (Courtesy: KEGG pathway) |
| PMC2774738__F3 | Specification of cell fate in the mammalian cochlea |
| PMC2774752__F1 | Puzzles, promises and a cure for ageing |
| PMC2774770__F1 | IL-4 induces an alternate pathway for BCR signalling |
| PMC2774790__F6 | Proteome Profile of Functional Mitochondria from Human Skeletal Muscle Using One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS |
| PMC2774854__F1 | Schematic overview about TCR-dependent signalling pathways |
| PMC2774878__F2 | The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. |
| PMC2775047__F1 | TLR Mediated Immune Responses in the Urinary Tract |
| PMC2775119__F3 | Ciliary functions of cystoproteins: mechanosensation and cell cycle control |
| PMC2775177__F1 | Branches of the UPR signalling pathway |
| PMC2775236__F1 | The effect of neuronal activity on the function of the miR379-410 cluster member miR-134 |
| PMC2775805__F6 | Molecular pathway analysis of genes regulated in the NAc by the HDAC inhibitor MS-275 after chronic social defeat stress |
| PMC2775888__F2 | Cellular mechanisms by which flavonoids and their metabolites protect against neuroinflammation and neuronal injury induced by 5-S-Cys-DA, DHBT-1 and related ROS |
| PMC2775948__F2 | Integrated Proteomic Analysis of Human Cancer Cells and Plasma from Tumor Bearing Mice for Ovarian Cancer Biomarker Discovery |
| PMC2776023__F6 | Metabolic network model |
| PMC2776288__F1 | Apoptosis pathways in mammalian cells |
| PMC2776288__F2 | Crosstalk between ionizing radiation-induced apoptosis and NFKB pathway |
| PMC2776288__F3 | Crosstalk between apoptosis and NFKB signaling by IAP-antagonist |
| PMC2776679__F7 | Egr-1 and Hipk2 are required for the TrkA to p75NTR switch that occurs downstream of IGF1-R |
| PMC2776723__F6 | Integration of activated transcription factors with the upstream signaling network during CB1R-induced neurite outgrowth |
| PMC2776748__F1 | A, Schematic diagram showing intra-cellular functions of the Bcl family of proteins |
| PMC2776915__F1 | A genetic model for sex determination, controlled by a balance of antagonistic pathways |
| PMC2777340__F4 | Drosophila insulin signaling pathway |
| PMC2777383__F1 | Predictive Phosphorylation Signature of Lung Cancer |
| PMC2777484__F1 | Folate-mediated 1-carbon metabolism |
| PMC2777795__F2 | Negative-feedback loop linking NAD+/SIRT1 with the Clock network |
| PMC2777959__F1 | Comparison of mixed acid pathway for glucose fermentation in native E |
| PMC2778015__F3 | Master regulator miRNA of oncogenic and tumor suppressor |
| PMC2778230__F3 | Apoptotic signaling in aging muscles |
| PMC2778287__F6 | Schematic representation of a dualistic model depicting the development of ovarian cancer |
| PMC2778342__F2 | Roles of the selected genes in the DSBR pathway |
| PMC2778660__F6 | Network representation of p53, NFKB and cell cycle interactions |
| PMC2778684__F1 | Canonical and non-canonical Wnt signaling pathways |
| PMC2778737__F4 | Nephron development and cell lineages |
| PMC2778955__F10 | Expression of an IKKG Splice Variant Determines IRF3 and Canonical NFKB Pathway Utilization in ssRNA Virus Infection |
| PMC2779044__F4 | Model describing the regulation of protein synthesis by AMPK, Ca++ and Akt -signaling pathways |
| PMC2779132__F6 | Schematics of the proposed participation of Pi4ka and PI3Ks in the FGF signaling cascade in the developing fin bud mesenchyme |
| PMC2779188__F1 | Genes involved in the vitamin D pathway |
| PMC2779759__F7 | Schematic model illustrating how Jun proteins regulate the TIMP-3, TACE, and TNFA pathway: Jun proteins transcriptionally activate TIMP-3 expression, which is responsible for TACE inhibition |
| PMC2780394__F7 | The signaling network of differentially expressed proteins |
| PMC2780603__F1 | EGF receptor-signal transduction pathway |
| PMC2780838__F1 | The complement cascade |
| PMC2780914__F3 | Transmigration causes differential expression of genes in the apoptosis pathway |
| PMC2781055__F3 | Ingenuity pathway analysis (IPA) of microarray data generated several genetic networks |
| PMC2781329__F4 | Schematic diagram for HO-1 modulation of signaling pathway and adiponectin, EET levels, and vascular function |
| PMC2781394__F8 | HGF-mediated inhibition of gluconeogenesis in primary hepatocytes |
| PMC2781439__F7 | Speculative model depicting mono-ubiquitination-dependent and independent functions of the FA-BRCA pathway in DNA replication-associated repair processes |
| PMC2781509__F1 | Folate-mediated one-carbon metabolism |
| PMC2781822__F2 | Resolution of immune activation defines nonpathogenic SIV infection |
| PMC2782081__F1 | An overview of miRNA biogenesis |
| PMC2782433__F1 | COPPER ACTIVATION OF NFKB SIGNALING IN HEPG2 CELLS |
| PMC2782452__F1 | Different views of the Akt pathway/network |
| PMC2782488__F1 | Cytokine signaling modules in inflammatory responses. |
| PMC2782488__F3 | Cytokine signaling modules in inflammatory responses |
| PMC2782644__F5 | Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs |
| PMC2782690__F3 | Is cancer a disease of abnormal cellular metabolism? |
| PMC2782725__F2 | Cell cycle and acute kidney injury |
| PMC2782733__F2 | EGFR signaling through the PI3K/Akt pathway |
| PMC2783241__F2 | Kidney development: from ureteric bud formation to branching morphogenesis |
| PMC2783351__F2 | "Toll" of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia |
| PMC2783472__F1 | Impaired DNA Damage Response - an Achilles' Heel Sensitizing Cancer to Chemotherapy and Radiotherapy |
| PMC2783472__F2 | Impaired DNA Damage Response - an Achilles' Heel Sensitizing Cancer to Chemotherapy and Radiotherapy |
| PMC2783518__F1 | Wnt signaling and senescence: a tug of war in early neoplasia? |
| PMC2783576__F2 | Mitotic removal of cohesin in humans: In humans, cohesins (pink) are removed from chromosome arms in prophase in a Plk1-dependent pathway |
| PMC2783774__F4 | miRNA process pathway |
| PMC2783837__F2 | TRAIL-R1/-R2 apoptotic signaling pathway |
| PMC2783859__F3a | Identification of Actively Translated mRNA Transcripts in a Rat Model of Early Stage Colon Carcinogenesis |
| PMC2783967__F6 | Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin |
| PMC2784025__F8 | Proposed model of the underlying mechanism by which NeuroD6 may bridge neuronal differentiation to survival |
| PMC2784121__F6 | NPM-ALK oncogenic tyrosine kinase controls T cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells |
| PMC2784255__F1 | Examination of Tetrahydrobiopterin Pathway Genes in Autism |
| PMC2784308__F1 | An illustration of the MC1R pigmentation pathway and the loci implicated in melanoma risk |
| PMC2784662__F1 | mTOR Signaling Cascade |
| PMC2784766__F3 | Complex role of the PLAU-PLAUR pathway in the airways |
| PMC2784807__F1 | IL-10 and IL-6 signaling pathways among 2,102 DEG due to IMI with Streptococcus uberis |
| PMC2784807__F3 | Cyclin-dependent kinase (CDK) 5 (A) and Insulin-like growth factor (IGF)-1 signaling pathways (B) among 2,102 differentially expressed genes due to intramammary infection with Streptococcus uberis |
| PMC2784807__F5 | Ingenuity Pathway Analysis® network depicting relationships among genes involved in immune and metabolic responses due to IMI with Streptococcus uberis |
| PMC2784899__F7 | Model to account for responsiveness to cAMP level in activation but not inactivation of eumelanin synthesis |
| PMC2785127__F5 | Putative targets of common changes in gene expression with single and repeated IMO stress |
| PMC2785342__F8 | A proposed model for HA-CD44-mediated PKCE activation and Nanog signaling in the regulation of miRNA-21 production, oncogenesis, and chemoresistance in breast tumor cells |
| PMC2785474__F2 | TLR signaling (an example in macrophages and dendritic cells) |
| PMC2785474__F4 | TLR4 and chemokine receptor cross-talk |
| PMC2785475__F4 | Expression-Based Network Biology Identifies Alteration in Key Regulatory Pathways of Type 2 Diabetes and Associated Risk/Complications |
| PMC2785495__F1 | Response of heterogeneous ribonuclear proteins (hnRNP) to ionizing radiation and their involvement in DNA damage repair |
| PMC2785495__F3 | Response of heterogeneous ribonuclear proteins (hnRNP) to ionizing radiation and their involvement in DNA damage repair |
| PMC2785525__F1 | The Anticoagulant APC Pathway |
| PMC2785525__F2 | Cytoprotective APC pathway |
| PMC2785619__F2 | Up-regulation of TGFB signaling in Timp3-/--AB hearts |
| PMC2785637__F1 | Schematic overview of hepatic lipid biosynthetic pathways |
| PMC2785769__F7 | Proposed pathways for promotion (A) and progression genes (B) influenced by TLR4 |
| PMC2785881__F3 | Sialic Acid Utilisation and Synthesis in the Neonatal Rat Revisited |
| PMC2785932__F3 | Four pathways by which the EBV latent membrane protein 1 (LMP1) is thought to signal inside cells |
| PMC2785984__F7 | A model of the regulation of DREB1 expression under circadian control |
| PMC2786169__F4 | Topology of leukemia-related BCR-ABL pathway |
| PMC2786705__F8 | Continued defect in IRF-3-deficient BMDCs |
| PMC2786808__F8 | Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice |
| PMC2786873__F9 | Model of amino acid starvation-induced AARE-dependent transcription in human cells |
| PMC2787458__F9 | Wnt3a stimulates Src docking to, activation by, and phosphorylation of Dvl2 |
| PMC2787631__F7 | Working model of PKA's role in trastuzumab resistance |
| PMC2787666__F1 | Base excision repair (BER) pathway |
| PMC2787666__F2 | The complex network of protein-protein interactions of Ape1 |
| PMC2787730__F10 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the focal adhesion pathway |
| PMC2787730__F11 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the apoptosis pathway |
| PMC2787730__F12 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the cell-adhesion pathway |
| PMC2787730__F9 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the cytokine and cytokine-receptor interaction pathway |
| PMC2787898__F1 | TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice |
| PMC2788007__F1 | Simplified representation of the complement cascade |
| PMC2788021__F3 | A model for torpor induction in mammals that links reduced availability of food in the environment with the energy status of the cell, the mammalian circadian clock, and response to oxidative stress |
| PMC2788154__F1 | Signaling pathways that lead from activated KIT and aggregated FcERI to mast cell responses |
| PMC2788159__F1 | Regulation of mTORC1 mTORC1 is a multiprotein complex composed of Raptor, mLST8, PRAS40, and FKBP38 and regulates protein synthesis and cell growth by phosphorylating S6K1 and 4EBP1 |
| PMC2788159__F2 | Current proposed mechanisms of amino acid sensing by mTORC1 Amino acids are imported into the cells via various amino acid transporters and activate mTORC1 either by amino acid metabolites or by undefined membrane/intracellular amino acid sensor(s) |
| PMC2788213__F4 | Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages |
| PMC2788225__F8 | ActRIIA and BMPRII Type II BMP Receptor Subunits Selectively Required for Smad4-Independent BMP7-Evoked Chemotaxis |
| PMC2788255__F6 | Wnt signalling pathway downregulated in osteosarcoma |
| PMC2788512__F7 | Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway. |
| PMC2788597__F3 | Metabolic pathway of pitavastatin |
| PMC2788936__F3 | Signaling and regulation of PRR-induced autophagy |
| PMC2789270__F1 | TGFB: A New Role for an Old AktTOR |
| PMC2789271__F1 | Gene selection in the TGFß signaling pathway |
| PMC2789488__F3 | Schema of major signaling pathways involved in renal development (for space and clarity, not all factors in each pathway shown) |
| PMC2789670__F5 | Summary of glutathione (l-Gamma-glutamyl-l-cysteinylglycine, GSH) homeostasis pathway identified in C |
| PMC2789784__F2 | Signaling pathway downstream of PI3K affect cell death and cell survival |
| PMC2789789__F6 | Scheme of the biosynthesis pathways for PC, PE, and PS in human P |
| PMC2790076__F5 | Comparative Analysis of Gene Expression Patterns and Cell Phenotypes between Cervical and Peripheral Blood Mononuclear Cells |
| PMC2790152__F3 | A model of the inhibitor of growth (ING) 2 signaling pathway |
| PMC2790217__F17 | Akt regulates growth by phosphorylating and inhibiting the TSC1-TSC2 complex in drosophila |
| PMC2790273__F1 | Possible cross-talk between Nod2, TCR, Cd28, TLR and TNFR family members in regulating NFKB |
| PMC2790404__F2 | Viral infection elicits a variety of antiviral cellular responses |
| PMC2790417__F10 | Summary of proposed role for Foxa2, Nodal and Hh signalling pathways in ventral CNS development |
| PMC2790539__F1 | Apoptosis in cerebral ischemia and reperfusion |
| PMC2790720__F2 | IRF4: Immunity. Malignancy! Therapy? |
| PMC2790753__F1 | Microarray data for the genes in the pathway coined from the central genes in the KEGG pathways 'insulin signaling pathway' and 'adipocytokine signaling pathway' |
| PMC2790850__F2 | Aberrant Myc expression causes mammary cancer |
| PMC2791157__F2 | Decomposition of Gene Expression State Space Trajectories |
| PMC2791157__F3 | Decomposition of Gene Expression State Space Trajectories |
| PMC2792482__F3 | Integration of lipid metabolic and inflammatory signaling in macrophages by LXRs |
| PMC2792912__F6 | Model of Six2 function during mouse pyloric sphincter development |
| PMC2793049__F2 | Leptin signaling and leptin resistance |
| PMC2793058__F10 | IFNG signaling pathway in retinal pigment epithelium |
| PMC2794539__F5 | Gene Expression Signature of Invasive Potential in Metastatic Melanoma Cells |
| PMC2794543__F8 | Activation of Wnt/Beta-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells |
| PMC2794709__F2 | O-GlcNAc and phosphate regulate the insulin signaling pathway at the plasma membrane |
| PMC2795398__F1 | Endotoxin binds to CD14 and Toll-like receptor 4 (TLR4) on the surface of monocytes and endothelial cells |
| PMC2795439__F1 | Androgen-receptor signalling in normal prostate and PCa |
| PMC2795496__F5 | A model on the action of EIN3/EIL1 and PIF1 in regulating cotyledon greening |
| PMC2796113__F2 | Models of Merlin-dependent membrane receptor distribution in flies and mammalian cells |
| PMC2796172__F2 | Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics |
| PMC2796182__F4 | Regulation of nitric oxide signaling by thrombospondin-1: implications for anti-angiogenic therapies |
| PMC2796203__F1 | Targeting the Transforming Growth FactorB Signaling Pathway in Human Cancer |
| PMC2796203__F2 | Targeting the Transforming Growth FactorB Signaling Pathway in Human Cancer |
| PMC2796930__F7 | FGF-receptor signalling in the generation of hindbrain neural cell diversity |
| PMC2796982__F3 | Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway |
| PMC2796989__F1 | Interleukin (IL)-13/transforming growth factor (TGF)B signalling pathways |
| PMC2797270__F8 | Summary of Trif-biased signaling and selective p38 activation by sMLA |
| PMC2797318__F2 | Promising bone-related targets for rheumatoid arthritis therapy |
| PMC2797409__F3 | Reconstructed CCM of S |
| PMC2797439__F1 | Class IA PI3K signalling pathway |
| PMC2797892__F10 | Pathway induction after pathophysiologic stimulation of BSMC by three coordinate stimuli: strain, hypoxia, and damaged matrix |
| PMC2798195__F9 | Proposed mechanism for pathogenesis due to H |
| PMC2798273__F1 | Role of CobT in the late steps of AdoCbl biosynthesis |
| PMC2798676__F10 | Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling |
| PMC2798710__F1 | New roles for Notch in tuberous sclerosis |
| PMC2799380__F6 | Connective tissue associated signalling network common to various cardiac hypertrophy animal models and human cardiac disease |
| PMC2799800__F1 | Scheme of the model for the mammalian cell cycle |
| PMC2799977__F2 | TLR signaling upon intrinsic cellular defenses |
| PMC2800820__F1 | Multiple pro-inflammatory mediators in the tumor microenvironment increase the accumulation of MDS cells and enhance their immunosuppressive activity |
| PMC2800957__F1 | Targets for lithium's neuroprotective effects |
| PMC2801177__F3 | Subnetworks of select putative DEP-regulated gene transcripts show an enrichment of inflammatory response |
| PMC2801177__F4 | Identification of candidate molecular network for miRNAs most highly changed in response to DEP |
| PMC2801237__F5 | Proposed revised model of mammalian DNA damage response |
| PMC2801257__F1 | Signaling through the Lymphocyte receptor induces a novel regulatory motif for MAP kinase activation |
| PMC2801624__F1 | A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches |
| PMC2801866__F1 | VEGF binding to VEGFR2 on endothelial cells activates its Tyr kinase activity and results in autophosphorylation of the receptor at several cytoplasmic sites |
| PMC2801866__F3 | Thrombospondin-1 (TSP1) binds to two receptors on endothelial cells that inhibit NO signaling |
| PMC2801866__F4 | NO/cGMP pathway is a signaling node for pro- and anti-angiogenic signaling |
| PMC2802426__F1 | Molecular mechanisms that regulate ionotropic glutamate receptor distribution during hippocampal mGluR-LTD induction and expression |
| PMC2802426__F2 | Schematic model of molecular mechanisms underlying regulation of gene transcription and protein translation during mGluR-LTD in postsynaptic neurons of hippocampal CA3-CA1 synapses |
| PMC2803240__F8 | Model of VA metabolism in neonatal rat lung |
| PMC2803288__F4 | Schematic diagram depicting the pathway via which GC-A signaling inhibits cardiac hypertrophy |
| PMC2803786__F2 | Network analysis of the top 250 predictor genes |
| PMC2804071__F4 | Joubert syndrome: insights into brain development, cilium biology and complex disease |
| PMC2804114__F1 | IR and IGF family signaling pathway |
| PMC2804177__F9 | The signaling pathways regulating osteoblast-like cells proliferation in response to OSS |
| PMC2804818__F5 | A summary of the ligand-mediated control of TRP53 expression via the PI3 kinase/AKT/MDM2 pathway |
| PMC2805009__F1 | Cross-talk between TCR and TGFB signaling networks |
| PMC2805044__F1 | The Akt/mTOR pathway in tobacco-carcinogen induced lung tumorigenesis |
| PMC2805399__F8 | A proposed working model of the complex Sertoli cell-germ cell interaction describing the mechanism by which Sertoli cells trigger germ cell apoptosis following MEHP-induced Sertoli cell injury |
| PMC2805685__F11 | Reconstruct part of KEGG pathway by our method |
| PMC2805706__F3 | Brain foods: the effects of nutrients on brain function |
| PMC2805793__F1 | Ligand binding and subsequent Erbb dimer formation initiates signaling through a complex array of intracellular pathways that initiate and control a range of cellular processes |
| PMC2806029__F2 | Ammonia detoxification pathway and mitochondrial sirtuins |
| PMC2806113__F6 | Working model of TGFB actions in renal interstitial fibrogenesis |
| PMC2806300__F8 | Reversal of EMT induced by TGFB1 |
| PMC2806370__F2 | Cell cycle pathway gene expression |
| PMC2806370__F3 | Pathway deregulation in ovarian cancer |
| PMC2806519__F8 | Prostaglandin F2Alpha-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway |
| PMC2806747__F1 | TLR4 signaling pathway can be activated via GAG fragments requiring CD44 and MyD88 or through LPS, which requires MyD88, LBP, and CD14 |
| PMC2807132__F2 | p38 signaling to the chromatin in muscle progenitor cells |
| PMC2807212__F3 | TGFB superfamily and FGF signaling pathways |
| PMC2807212__F2 | Hh and Wnt signaling pathways |
| PMC2807318__F8 | Summary of the AMPK and mTOR signaling pathways |
| PMC2807379__F4 | Nephronophthisis: Disease Mechanisms of a Ciliopathy |
| PMC2807379__F6 | Nephronophthisis: Disease Mechanisms of a Ciliopathy |
| PMC2807379__F8 | Nephronophthisis: Disease Mechanisms of a Ciliopathy |
| PMC2808051__F1 | Summary of the insulin/IGF signaling pathway, using the terminology for mammalian systems |
| PMC2808051__F6 | Mammalian target of rapamycin (mTOR) activation pathway |
| PMC2808051__F20 | Reversible phosphorylation regulation of the cell cycle |
| PMC2808058__F1 | Schematic of the Notch pathway |
| PMC2808058__F2 | The effects of the SOX4 and HOXC6 transcriptional networks on PI3K-AKT pathway activation in prostate cancer |
| PMC2808058__F3 | The effects of SOX4 and HOXC6 on Notch pathway activation and metastasis |
| PMC2808158__F7 | Schematic summary of effect of IL-4 priming on phagocytic and secretory capacities of MΦs |
| PMC2808176__F1 | Example of pathway segments corresponding to FALZ identified from breast cancer data (Figure drawn with Cytoscape) |
| PMC2808241__F7 | Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice |
| PMC2808370__F7 | Possible mechanism by which Wnt determines the specificity of signalling pathway |
| PMC2808458__F1 | Toll-like receptor signaling in cell proliferation and survival |
| PMC2808458__F2 | Toll-like receptor signaling in cell proliferation and survival |
| PMC2809500__F4 | Proteins upregulated during time course analysis in lung or bronchoalveolar lavage fluid (BAL) following intra tracheal instillation of 20 µg carbon nanopaticles (CNP) |
| PMC2809778__F2 | Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, Parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis |
| PMC2809919__F2 | Epithelial-mesenchymal interactions mediated by the Sonic Hedgehog pathway in the gut |
| PMC2810075__F6 | CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts |
| PMC2810084__F7 | TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice |
| PMC2810142__F9 | Network diagram of Sp1-interacting proteins |
| PMC2810284__F4 | TGF-Beta-mediated signaling function in epithelia including the seminiferous epithelium of adult rat testes |
| PMC2810291__F6 | Endonuclein functions |
| PMC2810358__F2 | Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas |
| PMC2810404__F6 | Hepatocyte expression of Serum Response Factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice |
| PMC2810486__F1 | The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections. |
| PMC2810509__F2 | BIOLOGY OF VASCULAR MALFORMATIONS OF THE BRAIN |
| PMC2810509__F3 | BIOLOGY OF VASCULAR MALFORMATIONS OF THE BRAIN |
| PMC2810550__F2 | Wnt signaling pathway involvement in cancer and neurodegeneration |
| PMC2810618__F8 | Signaling network model for heart valve development and remodeling |
| PMC2810629__F1 | Tale of Transforming Growth FactorB (TGFB) Signaling: A Soigné Enigma |
| PMC2810660__F1 | Autophagy and NFKB fight for fate |
| PMC2811067__F2 | Some of the stress response transcription factor pathways with homologs in N |
| PMC2811176__F2 | Cytosine Methylation Dysregulation in Neonates Following Intrauterine Growth Restriction |
| PMC2811231__F7 | Gene program of neutrophil recruitment and tissue injury based on gene expression and in vitro data |
| PMC2811646__F3 | Molecular targets in Nrf2/phase II enzymes pathway modulated by PEITC and SFN |
| PMC2811741__F7 | Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model |
| PMC2812385__F7 | Alternative mechanisms exist for the induction of inflammatory and apoptotic genes in the absence of the IFNA/B receptor during influenza virus infection |
| PMC2812679__F8 | TK-mediated signaling pathway promoting HaCaT keratinocyte migration |
| PMC2812698__F1 | Signalling pathways that regulate cell wall remodelling of Candida albicans |
| PMC2812788__F1 | HDL, ABCA1 and ABCG1 transporters in cholesterol efflux and immune responses |
| PMC2813054__F1 | Changes in Akt signaling with differentiation of CD8+ T cells and co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1)-blocked highly differentiated CD8+ T cells |
| PMC2813229__F4 | Pathway analysis result showing 18 differentially expressed proteins following 50% PH can be sorted into the c-myc pathway |
| PMC2814006__F1 | IL-1 and TNF signal transduction events |
| PMC2814006__F2 | IL-6 signalling events |
| PMC2814179__F1 | Therapeutic targeting of NOTCH1 signaling in T-ALL |
| PMC2814417__F7 | The postulated signaling of MAP kinase pathway in proliferating or differentiating HL60 cells |
| PMC2814418__F8 | VDR-dependent and auxiliary pathways that lead to deltanoid-induced monocytic differentiation of myeloid leukemia cells |
| PMC2814429__F2 | Regulation of autophagy and apoptosis |
| PMC2814453__F1 | Coupling between Akt-mediated cellular energy metabolism, cell survival and proliferation |
| PMC2814543__F4 | Nutrient sensing and inflammation in metabolic diseases |
| PMC2814769__F5 | Primary Cilium as a Complex Signaling Center |
| PMC2815016__F3 | Farnesol induces ER stress and activation of the unfolded protein response |
| PMC2815088__F4 | The Hexosamine Signaling Pathway |
| PMC2815088__F5 | Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine |
| PMC2815088__F6 | Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine |
| PMC2815132__F1 | Dopamine Synthesis Pathway: Dopamine's synthesis pathway begins with the amino acid tyrosine and is regulated by the activity of tyrosine hydroyxylase |
| PMC2815188__F2 | This presentation will focus on molecular mechanisms underlying transduction of BCR signals that enforce the antigen unresponsiveness of anergic B cells |
| PMC2815894__F2 | Network of ABA-induced stomatal closure |
| PMC2816010__F6 | Effect of dasatinib on the BCR-ABL signaling pathway |
| PMC2816026__F7 | Met signal transduction exploited by InlB from L |
| PMC2816169__F6 | Prokineticin (PROK1) induction of regulator of calcineurin 1 isoform 4 (RCAN1-4) and interleukin (IL-11) |
| PMC2817017__F2 | RAS-RAF-MEK-ERK signaling pathway |
| PMC2817383__F4 | Putative host signaling pathway induced by Y |
| PMC2817430__F1 | Phylogenomics of Sterol Synthesis: Insights into the Origin, Evolution, and Diversity of a Key Eukaryotic Feature |
| PMC2817557__F2 | Molecular Modulation of Intestinal Epithelial Barrier: Contribution of Microbiota. |
| PMC2817888__F3 | ATM/ATR DNA damage response pathway and its downstream effectors leading to either G1/S or G2/M phase arrest |
| PMC2818158__F1 | Inflammation at a molecular level: a simplified scheme |
| PMC2818223__F2 | GSK3 regulation of STATs, Smads, Beta-catenin, and NFAT |
| PMC2818233__F2 | Nuclear phosphoinositide-mediated stress response pathway |
| PMC2818238__F1 | Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates intracellular calcium signaling by different mechanisms |
| PMC2818240__F5 | Oxidative stress and glutathione in TGF-Beta-mediated fibrogenesis |
| PMC2818318__F4 | Regulation of Cell Cycle and RNA Transcription Genes Identified by Microarray Analysis of PC-3 Human Prostate Cancer Cells Treated with Luteolin |
| PMC2818736__F1 | Colorectal cancer (CRC) stem cell model |
| PMC2818872__F8 | Ras signaling in early B cell development |
| PMC2819006__F1 | Key mechanisms involved in colorectal carcinogenesis |
| PMC2819049__F3 | Different components of shelterin are dedicated to different aspects of the end-protection problem |
| PMC2819159__F2 | Obesity, Diet and Risk of Non-Hodgkin Lymphoma |
| PMC2819165__F2 | Genetic Susceptibility to Lymphoma |
| PMC2819219__F7 | Caspase Mediated Cleavage, IAP Binding and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NFKB Signaling |
| PMC2819346__F1 | Hepatic Overexpression of Glycerol-sn-3-phosphate Acyltransferase 1 in Rats Causes Insulin Resistance |
| PMC2819352__F6 | Relationship of GPAT4 to other enzymes in the pathway of de novo glycerolipid synthesis |
| PMC2819585__F7 | MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis |
| PMC2819730__F1 | Urine-based assays for the detection of bladder cancer |
| PMC2819754__F1 | Transcriptional regulation of the differentiation of Th1 cells |
| PMC2819754__F2 | Transcriptional regulation of the differentiation of Th2 cells |
| PMC2819802__F1 | Activation of apoptotic and survival pathways by TNF |
| PMC2820080__F4 | Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE |
| PMC2820080__F5 | Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE |
| PMC2820199__F3 | Network of proteins, functional classes and cell processes modulated in prostate cancer cells after curcumin treatment |
| PMC2820199__F4 | Curcumin's targets intracellular components implicated in cell proliferation signaling pathway in prostate cancer cells |
| PMC2820234__F3 | Suggested signaling of the early stages of 1,25D-induced monocytic differentiation |
| PMC2820251__F1 | Innate immune evasion strategies of influenza viruses |
| PMC2820251__F2 | Innate immune evasion strategies of influenza viruses |
| PMC2820477__F1 | Schematic junctional organization and Beta-catenin signaling in CNS ECs: comparison of brain and retina |
| PMC2820477__F2 | Scheme of known Wnt pathways |
| PMC2820587__F3 | AURKA interactions |
| PMC2820658__F1 | Induction of IFNs after virus infection in IFNB pretreated human DCs |
| PMC2820687__F2 | Some of the pathways that may contribute to the expression of D3 in pathologic ventricular remodeling |
| PMC2820725__F4 | Redox signaling responses in DCs and T cells during T cell activation |
| PMC2820748__F6 | Sites within the early steps of the insulin signaling pathway affected by OGT and O-GlcNAcylation |
| PMC2821201__F6 | A diagrammatic model to summarize the role and subcellular localization of survivin and its splice variants in the regulation of apoptosis and control of mitosis in cancer cells |
| PMC2821476__F3 | TNFA induced signaling |
| PMC2821718__F3 | Structure and signalling in the IL-17 receptor superfamily |
| PMC2821954__F2 | Portrayed here is a molecular pathway analysis of genes regulated in the mouse nucleus accumbens by a direct infusion of the HDAC inhibitor MS-275 after chronic social defeat stress |
| PMC2821977__F1 | All steroids derive from cholesterol, which can be synthesized within the brain for de novo neurosteroidogenesis () |
| PMC2822054__F1 | How the PI3K-AKT and MEK-ERK pathways regulate apoptosis in EGFR driven cancers |
| PMC2822437__F1 | Heterotrimeric G Proteins and Apoptosis: Intersecting Signaling Pathways Leading to Context Dependent Phenotypes |
| PMC2822520__F7 | A working model for endosomal transport involving CLC-5 and KIF3B interaction in polarized cells |
| PMC2822851__F1 | Signal transduction pathway from integrin receptors to actin cytoskeleton |
| PMC2822937__F7 | Downstream effectors of the ErbB receptor signalling pathway |
| PMC2822975__F1 | Asbestos has pleiotropic effects on cell signaling pathways |
| PMC2823977__F1 | REACTIVE OXYGEN SPECIES, CELLULAR REDOX SYSTEMS AND APOPTOSIS |
| PMC2824626__F1 | Pathway for cholesterol synthesis from 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) by HMG CoA reductase and its inhibition by statins |
| PMC2824633__F4 | Cyclin D3-specific deregulated genes and their functional networks |
| PMC2824740__F5 | Strain-induced quantitative mRNA-expression analysis of PDL cells related to MAP-kinase signalling and cell cycle, ECM and integrins, and growth factor pathways |
| PMC2824768__F4 | Entry into an ICL repair pathway depends on the mode of recognition |
| PMC2824905__F2 | IFITM Proteins Mediate the Innate Immune Response to Influenza A H1N1 Virus, West Nile Virus and Dengue Virus |
| PMC2825293__F2 | Nutrient sensing machinery in K- and L-cells |
| PMC2825553__F1 | Interplay of cellular stress signals with apoptosis pathways |
| PMC2825767__F1 | Adrenal insulin signaling and glucose transport gene expression is overexpressed in the chromogranin A (Chga) knockout mouse |
| PMC2825767__F2 | Adrenal cholesterol biosynthesis pathway gene expression is globally underexpressed in the Chga knockout mouse |
| PMC2825767__F3 | Hepatic cholesterol biosynthesis pathway gene expression is globally overexpressed in the Chga knockout mouse |
| PMC2826040__F4 | miR-200a is implicated in the type I interferon signaling pathway |
| PMC2826040__F5 | miR-223 is implicated in the CREB signaling pathway |
| PMC2826212__F2 | An intricate gene regulatory network controls OL differentiation |
| PMC2826517__F1 | The current understanding of PELP1 signaling pathway |
| PMC2826542__F1 | An Overview of IL-7 Biology and Its Use in Immunotherapy |
| PMC2826554__F1 | Beta-AR-dependent translation initiation |
| PMC2826600__F4 | Insulin and IGF1 signaling pathway to promote glucose uptake by GluT3 in neurons (shown) or GlutT4 in muscle (not shown) |
| PMC2826677__F1 | T-cell activation, proximal signalling complex and activation of transcription factors |
| PMC2826877__F2 | Insulin signaling pathway in adipose cells |
| PMC2827416__F5 | Impact of high dietary protein on lipid metabolism in porcine adipose tissue at body weight 60 kg |
| PMC2827616__F8 | Signaling pathways controlling ENS precursor migration and lamellipodia formation |
| PMC2828057__F1 | Genetic factors influencing cytarabine therapy |
| PMC2828273__F1 | Interconnections between p53 and IGF-1/AKT/mTOR pathways |
| PMC2828280__F2 | Canonical Wnt pathway |
| PMC2828612__F1 | Putative mechanism by which the UPS acts downstream of BDNF/TrkB signaling to ultimately regulate Alpha-synuclein aggregation |
| PMC2829054__F7 | Cdk2 Is Required for p53-Independent G2/M Checkpoint Control |
| PMC2829061__F7 | Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair |
| PMC2829067__F1 | Caspase-1 Activation via Rho GTPases: A Common Theme in Mucosal Infections? |
| PMC2829367__F1 | Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy. |
| PMC2829627__F2 | Tumor-associated angiogenesis is sustained through stromal microenvironment crosstalk |
| PMC2829627__F3 | PPARG agonists inhibit Stat3-mediated IL-6 gene expression in myeloma cells |
| PMC2830120__F3 | Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection |
| PMC2830572__F1 | TNF A inhibits erythropoiesis by direct and indirect effects |
| PMC2830935__F9 | Model of how the nuclear transport factor 2 and Ran may function in the import of the EcR-B1 in the 20E signal transduction pathway |
| PMC2830959__F3 | Genetic alterations of the Ras-dependent ERK1/2 pathway in cancer |
| PMC2830970__F1 | Schematics of the retroviral replication cycle |
| PMC2831005__F10 | Yeast cell cycle |
| PMC2831042__F7 | Proposed model of neurite outgrowth pathway in postnatal SVZ/RMS-derived neurons |
| PMC2831127__F7 | Proteins Secreted By Embryonic Stem Cells Activate Cardiomyocytes Through Ligand Binding Pathways |
| PMC2831232__F2 | NKT cells in immune-mediated pregnancy loss |
| PMC2831538__F3 | Autophagy regulation in response to stress |
| PMC2831839__F9 | A proposed mechanism of MNTX synergistic effects with temsirolimus on inhibition of VEGF-induced angiogenic events |
| PMC2832126__F1 | The multi-stage autophagic process |
| PMC2832144__F11 | Proposed model for the signal transduction pathways involved in TGFB1-mediated fibroblast-myofibroblast differentiation |
| PMC2832191__F3a | Regulation of autophagy induction in yeast and mammalian cells |
| PMC2832236__F5 | BS and M chloroplast distribution of proteins involved in primary carbon metabolism |
| PMC2832309__F2 | WWOX gene and gene product: tumor suppression through specific protein interactions |
| PMC2832675__F1 | Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement |
| PMC2832691__F3 | Binding of Herpes Simplex Virus Type-1 Virions Leads to the Induction of Intracellular Signalling in the Absence of Virus Entry |
| PMC2832838__F1 | CONVERTING HUMAN PLURIPOTENT STEM CELLS INTO BETA CELLS: RECENT ADVANCES AND FUTURE CHALLENGES |
| PMC2832945__F7 | Proposed mechanism for B2M mAb inhibition of AR and cell proliferation, survival, and progression through a MAPK/SREBP-1 signaling pathway in prostate cancer cells |
| PMC2833108__F6 | Sonic Hedgehog, Wnt and TGFB signaling pathway gene expression in CpG late treated macrophages [; ; ; ], see discussion |
| PMC2833108__F7 | TNFSFR and NFKB signaling activation during macrophage activation: CpG late responses |
| PMC2833197__F7 | Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway |
| PMC2833311__F6 | Signaling pathways involved in Alpha-TEA-induced apoptosis in human ovarian cancer cell lines |
| PMC2833340__F1 | Plane facts of PCP in the CNS |
| PMC2834246__F2 | Regulation of chromatin structure by drugs of abuse |
| PMC2834303__F9 | PI3K-Akt pathway negatively regulates LPS signaling and gene expression in mouse macrophages by inhibiting the activation of MAPKs |
| PMC2834432__F1 | Phosphatidylinositol 3-kinase (PI3K) signaling cascade |
| PMC2834467__F2 | Map showing relationship between genes positively correlated with plasma estradiol superimposed on Ingenuity map |
| PMC2834542__F5 | Actin cytoskeleton signaling pathway as represented by Ingenuity Pathway Analysis |
| PMC2834552__F11 | Schematic diagram of AGE-induced CTGF expression is shown |
| PMC2834616__F4 | EGR3 and miRNAs involving in signaling pathways and regulatory networks in schizophrenia and nervous system |
| PMC2834757__F9 | Upregulation of SOCS-3 and PIAS-3 Impairs IL-12-Mediated Interferon-Gamma Response in CD56+ T Cells in HCV-Infected Heroin Users |
| PMC2834833__F3 | GSK3: a multifaceted kinase in Wnt signaling |
| PMC2834863__F1 | Transforming growth factor beta (TGFB) and inflammation in cancer |
| PMC2835492__F4 | Regulation of MUC4 expression |
| PMC2835842__F1 | HSV-1-mediated antagonism of TLR-dependent, anti-viral pathways |
| PMC2835907__F3 | Synopsis of FGFR2b-mediated dermal-epithelial signaling in keratinocytes and sebocytes of sebaceous glands |
| PMC2836046__F7 | Proposal of the regulatory loop of miR-24, miR-34a, and HNF4A in bile acid synthesis |
| PMC2836122__F2 | Cytokine signaling through the JAK/STAT pathway |
| PMC2836529__F3 | Neurotrophin actions on the endothelial cell |
| PMC2836783__F2 | CD62L regulation by T-cell receptor (TCR) stimulation and Gc-cytokines |
| PMC2837270__F8 | Seoul virus suppresses NFKB-mediated inflammatory responses of antigen presenting cells from Norway rats |
| PMC2837360__F1 | Canonical Wnt/Beta-catenin pathway (modified after ()) |
| PMC2837572__F1 | Downstream signalling pathways of TNFA |
| PMC2837947__F2 | Disruption of metabolic pathways involved in fat pad mass trait in mouse models of the candidate genes |
| PMC2837985__F9 | Proposed model for the regulatory mechanisms of the Ras and cAMP signaling pathways in stress response and antifungal drug susceptibility in C |
| PMC2838081__F10 | Molecular pathways regulated by C/EBPB during E-induced proliferation of uterine epithelial cells |
| PMC2838200__F3 | Proposed scheme for how macrophage-based nanoparticle drug delivery could affect disease outcomes in neurodegenerative disorders |
| PMC2838317__F8 | Differences between TRAIL- and AD5-10-induced signaling pathways |
| PMC2838378__F1 | Simplified schematic of the IgE receptor (FcERI) signaling pathway |
| PMC2838378__F2 | Simplified schematic of the T cell receptor signaling pathway |
| PMC2838843__F3 | PTEN signaling pathway |
| PMC2839169__F1 | Simplified illustration of the epidermal growth factor receptor (EGFR) pathway with the RAS/MAPK and PIK3CA/PTEN cascades |
| PMC2839260__F1 | Schematic depiction of the signalling pathways stimulated by cholecystokinin (CCK) activation of the CCK1 receptor |
| PMC2839261__F1 | Effector pathways stimulated by Beta-ARs |
| PMC2839263__F2 | Emerging models for the role of Beta-arrestin in wingless (from Drosophila) and the oncogene int-1 (WNT) signalling |
| PMC2839281__F4 | Pigmentation Pathway Evolution after Whole-Genome Duplication in Fish |
| PMC2839414__F7 | Microbial Induction of Inflammatory Bowel Disease Associated Gene TL1A (TNFSF15) in Antigen Presenting Cells |
| PMC2839454__F2 | Too Old to Fight? Aging and its Toll on Innate Immunity |
| PMC2840045__F1 | Innate immune responses in allotransplantation |
| PMC2840099__F7 | Proposed model of miR-486 regulation and function in muscle cells |
| PMC2840158__F6 | Schematic showing cytoplasmic signaling pathway from ATM to TSC2 via LKB1 and AMPK to repress mTORC1 and induce autophagy |
| PMC2840217__F6 | Antioxidant and phase II detoxifying enzyme genes in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells |
| PMC2840217__F7 | Changes in cell cycle regulation in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells |
| PMC2840217__F8 | Alteration in Ubiquitin-Proteasome System (UPS) in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells |
| PMC2840217__F9 | Parkinson's disease (PD)-related gene pathway in response to MG132, methylmercury (MeHg), and cadmium (Cd) in MEF cells |
| PMC2840235__F1 | Blockade of the VEGF pathway with mAbs |
| PMC2840262__F2 | Autophagy and the Ubiquitin-Proteasome System in Cardiac Dysfunction |
| PMC2840670__F1 | K-ras mutation governs the effects of inhibition of epidermal growth factor receptor (EGFR) on the Ras/Raf/Mek signaling pathway |
| PMC2841057__F1 | Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension |
| PMC2841057__F4 | Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension |
| PMC2841148__F6 | Proposed TLR/NFKB signaling pathway activation in a non-infectious, high VT mechanical ventilation experimental model |
| PMC2841246__F4 | COX-2 inhibitors on apoptosis |
| PMC2841319__F1 | Pathogenesis of kidney disease in systemic lupus erythematosus |
| PMC2841329__F1 | Model for the role of ÃŽâ€Np73B in the DDR |
| PMC2841835__F1 | Host defence signaling pathways in Caenorhabditis elegans model |
| PMC2842081__F1 | Telomeres: protecting chromosomes against genome instability |
| PMC2842130__F9 | Redoxosomal signaling for IL-1B and TNFA pathways |
| PMC2842492__F2 | Transcripts regulating the mammalian cell cycle are up-regulated in the proliferative-phase endometrial epithelium |
| PMC2842525__F2 | IFNA signal transduction |
| PMC2843003__F3 | Epicardial-Myocardial Signaling Directing Coronary Vasculogenesis. |
| PMC2843167__F7 | Summary of the findings presented here |
| PMC2843459__F11 | Schematic diagram illustrating the proposed signaling pathway involved in LTA-induced cPLA2/COX-2-dependent airway inflammation |
| PMC2843693__F2 | Molecular Origins of Cancer |
| PMC2843714__F4 | Adaptation of Group A Streptococcus to Human Amniotic Fluid |
| PMC2844056__F2 | Ingenuity pathway analysis and expression profiles of genes involved in apoptosis that were uniquely up regulated in ER+ cells in response to EPA |
| PMC2844056__F5 | Ingenuity pathway analysis of genes up regulated in ER+ cell in response to AA shows that the ERK/MEK pathway was significantly associated with ER+ |
| PMC2844056__F6 | Insulin receptor cascade was uniquely up regulated in ER- cells when treated with AA |
| PMC2844056__F7 | Genes involved in cell-cell signaling significantly associated with ERbreast cancer cells in response to AA |
| PMC2844177__F9 | P38 MAPK signal transduction in melanogenesis |
| PMC2844310__F3 | Relationship of NFKB to genes identified as "linearly" changing with age on the basis of cocitation analysis (Genomatix BibliosphereTM) is shown as a Bibliosphere image |
| PMC2844426__F4 | Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS) |
| PMC2844640__F1 | Role of Radiation-induced TGF-beta Signaling in Cancer Therapy |
| PMC2844640__F3 | Role of Radiation-induced TGF-beta Signaling in Cancer Therapy |
| PMC2844927__F3 | Routes of interaction between epoxyeicosanoid and endocannabinoid signaling pathways |
| PMC2845642__F2 | Molecular Mechanisms of T cell Receptor and Costimulatory Molecule Ligation/Blockade in Autoimmune Disease Therapy |
| PMC2845723__F2 | The bile salt synthetic pathway |
| PMC2846056__F3 | Making the blastocyst: lessons from the mouse |
| PMC2846061__F3 | Ovary: basic biology and clinical implications |
| PMC2846071__F1 | Prevention trumps treatment of antibody-mediated transplant rejection |
| PMC2846156__F3 | Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer |
| PMC2846172__F5 | Microenvironmental and spatial regulation of signaling pathways controlling EMT |
| PMC2846630__F1 | Regulation of the mTOR pathway by nutrients (amino acids, glucose), stress and insulin/IGF-1 |
| PMC2847023__F3 | Vitamin D3-driven signals for myeloid cell differentiation - Implications for differentiation therapy |
| PMC2847412__F1 | Endoplasmic reticulum stress response as a potential therapeutic target in multiple sclerosis |
| PMC2847476__F3 | Immunoregulatory Functions of mTOR Inhibition |
| PMC2847521__F11 | Proposed model for the I3C disruption of a cross-regulatory positive feedback loop involving expression of GATA3 and ERA by stimulating the degradation of ERA protein |
| PMC2847666__F1 | The Bacillus subtilis set of two component signaling pathways |
| PMC2848014__F8 | Proteomics Reveals Novel Oxidative and Glycolytic Mechanisms in Type 1 Diabetic Patients' Skin Which Are Normalized by Kidney-Pancreas Transplantation |
| PMC2848030__F6 | How the presence of virus acts on innate immune system components, i.e |
| PMC2848237__F2 | Reconstruction of a KEGG pathway |
| PMC2848307__F1 | Survival pathways with their cross-talk and immune regulatory mechanisms are shown in this pictorial representation of the Reed-Sternberg (R-S) cell |
| PMC2849133__F4 | Main targets of RhoA and ROCK, involved in organization of the cytoskeleton |
| PMC2849646__F3 | Frequent amplification and overexpression of multiple EGFR-family-signaling components in non-small cell lung cancer (NSCLC) |
| PMC2849704__F1 | Homocysteine metabolism in liver and kidney |
| PMC2849832__F1 | IFNG signaling through the JAK/STAT1 pathway |
| PMC2849843__F1 | Schematic presentation of PI3K-Akt signaling |
| PMC2849843__F2 | Schematic presentation of Akt-mTOR signaling |
| PMC2849853__F5 | Regulation of the Hypothalamic Thyrotropin Releasing Hormone (TRH) Neuron by Neuronal and Peripheral Inputs |
| PMC2850388__F7 | Dkk4 and Eda Regulate Distinctive Developmental Mechanisms for Subtypes of Mouse Hair |
| PMC2850427__F2 | Simplified Overview of the Purine Metabolism PathwayThe scheme is derived from KEGG Pathways hsa00230 (purine metabolism) and hsa00240 (pyrimidine metabolism) |
| PMC2850885__F7 | Proposed model of a EGFR/Beta-catenin/cyclin D1 signaling pathway in oral cancer |
| PMC2851161__F1 | The Notch signaling pathway |
| PMC2852112__F1 | Scheme of the autophagy pathway |
| PMC2852112__F2 | Anti-viral and pro-viral functions of autophagy |
| PMC2852400__F7 | Inhibition of the Proprotein Convertases Represses the Invasiveness of Human Primary Melanoma Cells with Altered p53, CDKN2A and N-Ras Genes |
| PMC2852600__F2 | CD40 responsiveness in Leishmania-infected macrophages: crosslinking of anti-CD40 antibody activates p38 MAPK-induced leishmanicidal function via iNOS2 induction |
| PMC2852602__F2 | TLR/IL-1R signalling pathways |
| PMC2853371__F9 | CD28 costimulation, IL-2 signaling, and mTOR pathway regulate Otub1 and GRAIL expression, controlling proliferation in primary naive CD4 T cells |
| PMC2853417__F4 | Differentially expressed genes in the cAMP signaling pathway |
| PMC2853417__F5 | Differentially expressed genes in the TGFB signaling pathway |
| PMC2853417__F6 | Differentially expressed genes in the ERK/MAPK signaling pathway |
| PMC2853417__F7 | Differentially expressed genes in the estrogen receptor signaling pathway |
| PMC2853973__F1 | Kaposi's sarcoma-associated herpesvirus and innate immunity |
| PMC2854141__F9 | Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease |
| PMC2854193__F1 | Autophagy Genes as Tumor Suppressors |
| PMC2854204__F1 | TOR-dependent control of autophagy: biting the hand that feeds |
| PMC2854249__F1 | Mammalian autophagy: core molecular machinery and signaling regulation |
| PMC2854249__F2 | Mammalian autophagy: core molecular machinery and signaling regulation |
| PMC2854285__F1 | mTOR and cancer: many loops in one pathway |
| PMC2854285__F2a | mTOR and cancer: many loops in one pathway |
| PMC2854298__F8 | AATF mediates anti-apoptotic effect of the unfolded protein response through transcriptional regulation of AKT1 |
| PMC2854301__F9 | The Transcriptional Repressor REST/NRSF modulates Hedgehog Signaling |
| PMC2854308__F1 | Signaling complexes induced by TNFA to mediate NFKB activation, apoptosis and necroptosis |
| PMC2854673__F1 | Minimally oxidized LDL induces TLR4-dependent lipoprotein uptake by macrophages |
| PMC2855089__F2 | NFKB Signaling Pathway |
| PMC2855202__F3 | Cross-talk between the hexosamine biosynthesis pathway, O-GlcNAc modification of proteins, signaling events downstream of insulin action, and glucose-induced adipocytokine secretion |
| PMC2855642__F2 | Glycosylation of Alpha-dystroglycan |
| PMC2855646__F7 | Summary of biosynthetic pathway for O-mannosyl glycans on A dystroglycan in mammals |
| PMC2855687__F1 | The kynurenine pathway with relevant regulatory components, summarizing gene expression and metabolite changes previously identified for schizophrenia in the frontal and anterior cingulate cortex |
| PMC2856263__F6 | Signaling pathways activated by DMXAA |
| PMC2856329__F9 | Brx-mediated osmotic stress-activated signaling system and its implications for the immune response |
| PMC2856448__F1 | Opposing influences on Foxo cellular localization and transcriptional activity |
| PMC2856528__F1 | The three complement activation pathways, converging to cleave C3 |
| PMC2856637__F1 | Simplified scheme of early FcERI-mediated signaling events |
| PMC2856676__F1 | Comparative Genomics of Flowering Time Pathways Using Brachypodium distachyon as a Model for the Temperate Grasses |
| PMC2856775__F1a | Convergence of Pathways in TLR and IL-1R SignalingUpon activation, the IL-1 receptor dimerized with the IL-1 receptor accessory protein |
| PMC2857022__F7 | Mechanistic model of KLF11-mediated tumor suppression and its antagonism by an oncogenic pathway |
| PMC2857099__F6 | Proposed model for NFKB repression by TRAF3 in LTBR activation |
| PMC2857169__F5 | NFKB in conventional T-cell activation |
| PMC2857176__F3 | Map of selected p53 pathway-associated genes that harbor known or potential functional SNPs (octagon-shaped boxes) and their closely interacting genes (rectangular boxes) |
| PMC2857179__F1 | Mechanisms and pathways targeted by mutations in MPN |
| PMC2857326__F7 | TGFB induces apoptosis in human B cells via transcriptional regulation of BIK and BCL-XL |
| PMC2857646__F1 | Schematic of the TGFB signaling pathway |
| PMC2857869__F4a | Metabolic Engineering for Production of Biorenewable Fuels and Chemicals: Contributions of Synthetic Biology |
| PMC2858157__F6 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858157__F7 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858157__F8 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858157__F9 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858431__F1 | Developing Antiepileptogenic Drugs for Acquired Epilepsy: Targeting the Mammalian Target of Rapamycin (mTOR) Pathway |
| PMC2858440__F5 | Four flux sensors of the in silico cell |
| PMC2858442__F3 | Model of CD95-mediated signaling |
| PMC2858523__F1 | Schematic diagram showing the RAS-MAPK signal transduction pathway and affected disease genes in disorders of the neurocardiofacialcutaneous syndrome family |
| PMC2858611__F3 | Depiction of the "Reelin signalling in neurons" pathway generated by Ingenuity |
| PMC2858667__F1 | Endocannabinoids Differentially Modulate Synaptic Plasticity in Rat Hippocampal CA1 Pyramidal Neurons |
| PMC2858867__F1 | ALPS - Ten Lessons from an International Workshop on a Genetic Disease of Apoptosis |
| PMC2858906__F1 | Main steps and key regulators in blood and lymphatic vasculature development |
| PMC2859139__F1 | Immunoregulatory pathways |
| PMC2859499__F7 | TAK1·TAB2·NLK complex negatively regulating canonical Wnt pathway |
| PMC2859933__F9 | Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-Infected Brain: Novel Analysis of Retrospective Cases |
| PMC2860204__F3 | Intrinsic and extrinsic apoptotic pathways |
| PMC2860204__F4 | Integrin signalling at focal adhesions |
| PMC2860235__F7 | FunCoup subnetwork of candidate cancer gene RPA1 surrounded by functionally coupled known cancer genes |
| PMC2860309__F1 | EDA signaling |
| PMC2860348__F1 | p38 MAPK mediates the transcriptional response to stress |
| PMC2860379__F2 | Genes affecting dystroglycan glycosylation associated with congenital muscular dystrophy |
| PMC2860555__F1 | Endosomal and cytoplasmic pathways for virus recognition and IFN production |
| PMC2860598__F4 | Control of the IFNG axis and the GAIT paradigm of translational silencing |
| PMC2860693__F8 | Simplified model of the signaling pathways regulating radiation-induced bystander effects |
| PMC2860895__F1 | TOM1L2 and genes associated with Alzheimer's disease in the human interactome |
| PMC2860937__F1 | Caveat mTOR: aberrant signaling disrupts corticogenesis |
| PMC2861144__F1 | Novel targets for the treatment of autosomal dominant polycystic kidney disease |
| PMC2861144__F2 | Novel targets for the treatment of autosomal dominant polycystic kidney disease |
| PMC2861185__F2 | Models of the Hippo pathway in Drosophila and mammals |
| PMC2861286__F1 | Proposed mechanism for vitamin D's action on the innate immune system |
| PMC2861325__F9 | An Ingenuity pathway analysis containing about half of the genes in subfactor 8 of Myc factor 6 |
| PMC2861543__F6 | Differential role for endocytosis in receptor-dependent Nox1 generation of ROS and activation of cellular signalling |
| PMC2861828__F1 | Signaling pathway that connects store-operated Ca2+ entry with NFAT-dependent gene transcription in T cells |
| PMC2861866__F3 | Hypothetical model linking multiple biological pathways in the development of SS-like disease based on differentially expressed genes identified in lacrimal glands by global microarray analyses |
| PMC2861953__F2 | Altered signaling pathways and mouse models of thyroid cancer |
| PMC2862089__F1 | Signal transduction pathways and crosstalk activated by insulin/IGF-1 receptor and GPCR systems |
| PMC2862093__F6 | Glucagon-like Peptide-1 Receptor (GLP-1R) is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway |
| PMC2862795__F1 | Multi-component nature of TGFB and Wnt Pathways |
| PMC2862867__F4 | Sites of action of curcumin on cancer cells |
| PMC2862880__F3 | Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer |
| PMC2863124__F1 | DNA damage and replication checkpoints in various organisms |
| PMC2863215__F2 | Regulation of mTORC signaling networks |
| PMC2864141__F1 | Models of checkpoint control in (a) S |
| PMC2864389__F1 | PI3K/AKT signaling pathway |
| PMC2864407__F1 | Description of the sex hormone metabolic pathway: genes involved in synthesis, bioactivation, metabolism, and inactivation of estrogen and other hormones |
| PMC2864432__F3 | Insulin/IGF1 signalling pathways and AD |
| PMC2864453__F1 | Nuclear factorKB (NFKB) can be activated by a multitude of different stimuli, like TNFA, LPS and CD40L |
| PMC2864659__F1 | Schematic overview of DNA-repair pathway |
| PMC2864659__F6 | APE1 has dual roles in redox and DNA repair |
| PMC2864663__F4 | Aging-related upregulation of AP-1 signaling in VSMC |
| PMC2864663__F5 | Aging-related upregulation of NFKB signaling in VSMC |
| PMC2864712__F10 | PAK4 regulates adhesion and migration via multiple signalling pathways |
| PMC2864762__F13 | CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells |
| PMC2864807__F2 | PPAR Signaling Pathway and Cancer-Related Proteins in Celiac Disease-Associated Tissue Damage. |
| PMC2864813__F4a | Substance P in Polymicrobial Sepsis: Molecular Fingerprint of Lung Injury in Preprotachykinin-A-/- Mice |
| PMC2865177__F1 | ER stress-induced apoptotic pathways |
| PMC2865336__F7 | Role of Rad9A in the G2 decatenation checkpoint |
| PMC2865489__F1 | The estradiol-synthetic pathway and nuclear receptors |
| PMC2865925__F5 | F igure 5.– |
| PMC2866107__F5 | Current Status of Xenotransplantation and Prospects for Clinical Application |
| PMC2866141__F4 | Molecular Basis of Pulmonary Alveolar Proteinosis |
| PMC2866836__F1 | Mitochondrial Ca2+ channels/transporters and role in mitochondrial function |
| PMC2867239__F2 | The Primary Cilium as a Hedgehog Signal Transduction Machine |
| PMC2867239__F5 | The Primary Cilium as a Hedgehog Signal Transduction Machine |
| PMC2867412__F2 | Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation) |
| PMC2867902__F6 | A feed forward loop for nutritional regulation of PNPLA3 |
| PMC2868782__F3 | Comparison of protein and gene expression studies |
| PMC2868837__F3 | Major gene products affected by virulent infection |
| PMC2869029__F1 | Regulation of macrophage function in tumors: the multifaceted role of NFKB |
| PMC2869094__F1 | Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia |
| PMC2869400__F9 | A model of Gfi-1-mediated repression of CDKN1A and other Miz-1 target genes |
| PMC2869512__F3 | Signaling pathway for zinc prevention of atherosclerosis in monocytes/macrophages and vascular endothelial cells: a proposed hypothesis |
| PMC2869518__F3 | Proximal signaling events in the TCR-coupled signaling pathway |
| PMC2869521__F1 | Role of BCR signaling to NFKB in ABC DLBCL |
| PMC2869521__F3 | Constitutive NFKB pathway activation in multiple myeloma |
| PMC2869521__F4 | Solid tumors activate the NFKB pathway to maintain cell survival |
| PMC2869556__F1 | Metabolic folate pathway |
| PMC2871322__F1 | Schematic of central regulation of body fluid regulation in response to acute changes in sodium and volume |
| PMC2871322__F3 | Schematic diagram of the forebrain neurocircuitry and peripheral inputs underlying the influences of osmotic and peripheral angiotensin II (Ang II) on sympathetic outflow and the baroreflex |
| PMC2871498__F9 | Working model for S1P/SK/S1PR interplay during acrosomal exocytosis |
| PMC2871634__F4 | WNT/Beta-catenin signaling pathway |
| PMC2871634__F5 | Regulation of apoptosis |
| PMC2871659__F1 | Overall scheme of key genetic and epigenetic events in colorectal tumorigenesis |
| PMC2871738__F2 | Molecular determinants of mitochondrial quality-control networks |
| PMC2871738__F3 | Role of the major PD-associated genes in mitochondrial dysfunction |
| PMC2871799__F6 | Human endometrial receptivity |
| PMC2871922__F4 | Regulation of spermatogenesis processes by non-classical testosterone signalling |
| PMC2872012__F4 | Functional genetic network as defined by the bioPIXIE tool (Myers et al |
| PMC2872012__F5 | Detailed representation of the interactions between the components of the gene network |
| PMC2872116__F1 | Analysis of a protein interaction network in the context of the T-cell pathway |
| PMC2872116__F2 | Structuring protein interactions around familiar canonical pathways provides intuitive visualizations |
| PMC2872207__F3 | Jak/STAT signaling pathway |
| PMC2872207__F4 | Akt signaling pathway |
| PMC2872486__F8 | An antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p |
| PMC2872497__F4 | Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment |
| PMC2872667__F3 | Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling |
| PMC2872667__F4 | Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling |
| PMC2872883__F2 | TIF scores for genes in the KEGG colorectal cancer pathway |
| PMC2872883__F3 | Small cell lung cancer |
| PMC2873055__F9 | ACBD3-mediated signaling pathway and cellular regulation |
| PMC2873428__F8 | Sequencing, Analysis, and Annotation of Expressed Sequence Tags for Camelus dromedarius |
| PMC2873439__F7 | CXCR5 activate PI3K isoforms through GAlpha-Src-FAK pathway or via GB/G pathway leading to subsequent activation of ERK1/2 |
| PMC2873688__F4 | Molecular mechanism and pathway of JNK activation by p85 |
| PMC2873801__F4 | Relationships between differentially expressed miRNAs, putative target genes, and functions |
| PMC2874080__F2 | Pathway of de novo synthesis of saturated and monounsaturated fatty acids and regulation of lipogenic genes by transcription factors (LXR, SREBP-1c and ChREBP) |
| PMC2874116__F2 | Intrinsic pathway is deregulated in cancer |
| PMC2874225__F1 | The DSBR and SDSA meiotic recombination models |
| PMC2874322__F4 | An Update on the Genetics of Atopic Dermatitis: Scratching the Surface in 2009 |
| PMC2874322__F5 | An Update on the Genetics of Atopic Dermatitis: Scratching the Surface in 2009 |
| PMC2874340__F1 | Folate cycle, methionine cycle, and transsulfuration pathway |
| PMC2874439__F3 | Schematic representing the significant changes in gene expression in the lung of Keap1ÃŽâ€2-3/ÃŽâ€2-3;CctCre+ mice compared with Keap1flox/flox mice |
| PMC2874622__F2 | The Role Of Mitochondria In The Mammalian Antiviral Defense System |
| PMC2874810__F3 | Ingenuity Pathway Analysis Network |
| PMC2875058__F2 | Several disease pathways involved in AD pathogenesis |
| PMC2875073__F5 | Albumin alters TGFB pathway gene expression |
| PMC2875112__F1a | Targeting Multiple Kinase Pathways. A Change In Paradigm |
| PMC2875223__F2 | The MSI pathway of human colon cancer |
| PMC2875624__F1 | Alterations in transforming growth factor beta signaling cause changes in chondrocyte differentiation and osteoarthritis development |
| PMC2875805__F10 | Cartoon illustrates genomic and nongenomic actions of VDR signaling in inhibition of human CYP7A1 gene transcription in human hepatocytes |
| PMC2876151__F7 | Cdk1 modulates the activity of several DNA damage checkpoint proteins |
| PMC2877394__F1 | ER and SR interactions within mammalian cells |
| PMC2877703__F1 | Anabolic and catabolic pathways regulating skeletal muscle mass |
| PMC2877959__F3 | Uric acid transport and disease |
| PMC2877983__F4 | Schematic illustration of phosphorylation events in central metabolic pathways |
| PMC2878012__F5 | Model for the role of SQSTM1 in regulating the integrity of the Keap1-Nrf2 cell defense pathway |
| PMC2878081__F7 | Schematic overview of the pyruvate/isocitrate cycle and OGC, important components of the pathway regulating glucose- and glutamine-stimulated insulin secretion |
| PMC2878746__F1 | Ret gene structure and signaling |
| PMC2878851__F1 | Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures |
| PMC2878851__F3 | Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures |
| PMC2878924__F5 | DNA damage checkpoint pathways |
| PMC2878924__F6 | Two models for coupling the circadian clock to the cell cycle/checkpoint response |
| PMC2879143__F3 | Activation of apoptotic signaling via caspase 3 and gelsolin |
| PMC2879143__F4 | Signaling cluster and integrin signaling |
| PMC2879321__F1 | Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis |
| PMC2879563__F1 | Subdivision of the estrogen metabolic pathway |
| PMC2879972__F4 | Illustration of different mechanisms of MUC1 and MUC4 for the repression of apoptosis |
| PMC2880289__F6 | Complex deregulation of the Neuregulin/ERBB2 signaling pathway |
| PMC2880413__F2 | Networks for (A) Biological network (B) Network MDL approach (C) PMDL approach The performance on the algorithms is performed on a biological data set |
| PMC2880454__F1 | Targeting the cancer kinome through polypharmacology |
| PMC2880522__F1 | Results of a Pathway Studio® analysis of direct relationships between the components of the protein-bound fraction of renal cyst fluid |
| PMC2880683__F1 | Insulin signaling pathway |
| PMC2880865__F8 | Revitalization of a diastemal bud |
| PMC2881215__F1 | Signaling in podocyte apoptosis |
| PMC2881280__F1 | Schematic representation of the proposed enzymatic steps in the FAC -elicited JA biosynthesis pathway regulated by SIPK, WIPK and NPR1 |
| PMC2881367__F7 | CircleMap display of the ErbB2 pathway |
| PMC2881756__F7 | Model illustrating the role of WDR3 in mediating cross-talk between ribosome biogenesis and p53-mediated cell cycle regulation |
| PMC2882122__F4 | Selection of expression patterns and activities of members of the cadherin superfamily in cancer |
| PMC2882184__F1 | Pathway analysis using all altered genes and proteins |
| PMC2882188__F3 | Complement cascade |
| PMC2882232__F2 | Simplified representation of oncogenic signaling cascades in pancreatic cancer |
| PMC2882520__F3 | Disease associations in the hypothalamus (genes regulated at p<0.001; fold change > ±1.5) |
| PMC2882531__F1 | Retinoids for Treatment of Retinal Diseases |
| PMC2882734__F6 | Pathways of VLC-PUFA biosynthesis |
| PMC2882741__F1 | Schematic view of the GSL metabolism pathways |
| PMC2882796__F1 | Does Activation of the Blood Coagulation Cascade Play a Role in Malaria Pathogenesis? |
| PMC2882865__F2 | Transcriptional regulation by E2F complexes modulates cell-cycle control, cell fate, and survival |
| PMC2883240__F1 | Signaling pathways involving molecular markers for human breast cancer |
| PMC2883292__F2 | Signaling through the PI-3 Kinase-Akt pathway |
| PMC2883337__F1 | Chromaffin cell genes involved in catecholamine biosynthesis, storage, secretion and degradation |
| PMC2883511__F1 | Signaling pathways and targets for LAM |
| PMC2883603__F4 | Carbon Assimilation Network in Escherichia coli Is Densely Connected and Largely Sign-Determined by Directions of Metabolic Fluxes |
| PMC2883790__F2 | IGF-I activation of a signaling pathway to mTOR |
| PMC2884012__F1 | Tuberous Sclerosis Complex: A Brave New World? |
| PMC2884164__F5 | Significant signaling pathway networks mined from pituitary adenoma comparative dataset |
| PMC2884164__F9 | ERK/MAPK signaling pathway that is involved with pituitary adenoma comparative-proteomic data |
| PMC2885101__F2 | PI3K/Akt signaling pathway |
| PMC2885424__F7 | Transcriptional Regulation of the IGF Signaling Pathway by Amino Acids and Insulin-Like Growth Factors during Myogenesis in Atlantic Salmon |
| PMC2885511__F2 | Diagram of PDGF-D cross-talks with other pathways |
| PMC2885591__F1 | With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging |
| PMC2885591__F2 | With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging |
| PMC2885703__F11 | WNT1-Inducible Signaling Pathway Protein-1 Activates Diverse Cell Survival Pathways and Blocks Doxorubicin-induced Cardiomyocyte Death |
| PMC2885761__F2 | Schematical overview of the signaling pathway mediated by MC1R |
| PMC2885902__F2 | Mitochondrial biochemical pathways that are involved in KATP-independent GSIS |
| PMC2886068__F2 | Bile salt synthetic pathways |
| PMC2886153__F1 | Schematic representation of the intracellular cholesterol transport pathway |
| PMC2886162__F5 | SIRT1-dependent Regulation of Chromatin and Transcription: Linking NAD+ Metabolism and Signaling to the Control of Cellular Functions |
| PMC2886300__F2 | Role of ROS in TNFA induced endothelial dysfunction |
| PMC2886325__F3 | PI3K-Akt-mTOR pathway and cross-talk with other signaling cascades: (Ras/Raf/MAPK and BCR-ABL) |
| PMC2886330__F1 | Simplified diagram of the two major pathways affected by EGFR-mediated signaling in malignant glioma cells |
| PMC2886346__F10 | The pathway signaling to ERESs |
| PMC2886808__F1 | Signalling through growth factor receptors can activate the PI3K/Akt/mTOR pathway and the JAK3/STAT5 pathway |
| PMC2886982__F3 | Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes |
| PMC2887084__F1 | New Strategies in Head and Neck Cancer: epidermal growth factor receptor inhibition in head and neck cancer. |
| PMC2887259__F5 | Signaling cascades that regulate A |
| PMC2887297__F1 | Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease |
| PMC2887331__F2 | Serine/threonine kinase Akt, also known as protein kinase B (PKB), has become a major focus of attention because of its critical regulatory role in diverse cellular processes, including cancer progression |
| PMC2887678__F1 | Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells. |
| PMC2887830__F2 | Regulation of intracellular Stat3 signalling |
| PMC2888385__F6 | Nodal-Smad2 signaling regulation of the BMP pluripotency pathway in mouse ES cells |
| PMC2888472__F2 | Simplified scheme of signaling pathways required for maintenance of pluripotency of mESC (top panel) and hESC (bottom panel) |
| PMC2888474__F2 | Genetic Alterations in Glioblastoma Occur Frequently in 3 Cellular Signaling Pathways |
| PMC2888475__F1 | Cellular apoptosis pathways and intervention by both cellular anti-apoptotic proteins and viral proteins encoded by oncolytic Ad, HSV and VV |
| PMC2888582__F6 | Proteomics-Based Systems Biology Modeling of Bovine Germinal Vesicle Stage Oocyte and Cumulus Cell Interaction |
| PMC2888634__F4 | Drug-induced DNA damage may be repaired by various DNA repair pathways, or apoptosis may be triggered as a result of attempted repair of platinum-induced damage by the Mismatch Repair pathway |
| PMC2888641__F1 | Targeting Hedgehog - a Cancer Stem Cell Pathway |
| PMC2889025__F1 | Response of p53 to DSBs generated by ionizing radiation |
| PMC2889025__F2 | P53 stabilization |
| PMC2889025__F4 | Crosstalk between the PI3K/AKT pathway and p53 activation: Potential stratagies for combined radiosensitization |
| PMC2889494__F3 | Protein components of the pheromone response network constructed by the PCST approach |
| PMC2889604__F7 | The regulation of neuronal migration and neurite outgrowth by the MRTF/Srf pathway |
| PMC2889681__F1 | Neurotrophic and neuroprotective pathways targeted by lithium |
| PMC2889938__F2 | Target gene regulatory network, NFKB/RelA:P50 |
| PMC2890032__F2 | Differential vulnerability of neurons in Huntington's disease: The role of cell type-specific features |
| PMC2890409__F1 | Classification of Dengue Fever Patients Based on Gene Expression Data Using Support Vector Machines |
| PMC2890502__F2 | The yeast MAPK signalling pathways deposited in KEGG [] |
| PMC2890581__F7 | Inflammatory Mediator TAK1 Regulates Hair Follicle Morphogenesis and Anagen Induction Shown by Using Keratinocyte-Specific TAK1-Deficient Mice |
| PMC2890584__F6 | Mu-Opioid Receptors Transiently Activate the Akt-nNOS Pathway to Produce Sustained Potentiation of PKC-Mediated NMDAR-CaMKII Signaling |
| PMC2891025__F6 | Deep mRNA Sequencing for In Vivo Functional Analysis of Cardiac Transcriptional Regulators: Application to GAq |
| PMC2891151__F1 | TGFB ligands signal through the type I and type II TGFB receptors |
| PMC2891338__F1 | Endotoxin binding: Schematic overview of the LPS, LBP, CD14 and TLR-4 signal transduction pathway |
| PMC2891586__F3 | Protein-Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks |
| PMC2891859__F1 | General overview of BDNF and GDNF signaling mechanisms |
| PMC2891887__F2 | Lymphangiogenesis and Lymphatic Metastasis in Breast Cancer. |
| PMC2891946__F7 | Crosstalks between EPCR, PAR-1, S1P1, and Tie2 |
| PMC2891948__F2 | Addicted Synapse: Mechanisms of Synaptic and Structural Plasticity in Nucleus Accumbens |
| PMC2891968__F5 | Cellular pathways leading to upregulation of COX-2 in neutrophils |
| PMC2892252__F1 | Host responses to Candida albicans: Th17 cells and mucosal candidiasis |
| PMC2892298__F8 | Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors |
| PMC2892366__F10 | A model for the function of GCN2, ATF4, ASNS and Asn in conferring tumour cell protection from microenvironment stress |
| PMC2892459__F4 | Snapshots from the integrated macrophage pathway diagram |
| PMC2892459__F5 | Overlay of IfnB timecourse analysis onto the macrophage pathway using BioLayout Express3D |
| PMC2893101__F3 | Apoptosis Signalling network |
| PMC2893383__F2 | Schematic of leptin signaling through STAT3 and PDE3B pathways in POMC and NT neurons in the hypothalamus |
| PMC2893543__F4 | Schematic overview of costimulatory receptors and their ligands |
| PMC2893682__F7 | Interaction scheme of Shh and activated Beta-catenin signaling |
| PMC2894370__F4 | "Where, O Death, Is Thy Sting?" A Brief Review of Apoptosis Biology. |
| PMC2894449__F1 | Stages of apoptotic cell engulfment and associated cell signaling events that regulate each stage |
| PMC2894618__F2 | Lineage relationships of cells originating in the otocyst |
| PMC2894843__F3 | Ingenuity Pathway Assist (IPA) analysis of significant genes involved in cell death |
| PMC2894844__F7 | Schematic drawing of Akt/GSK-3B/tau signaling |
| PMC2895369__F1 | High-flux and low-flux systems of electron transfer pathways |
| PMC2895370__F1 | TLR4 signaling: The MyD88-dependent pathway through PDCD4 |
| PMC2895421__F2 | Convergent signaling pathways where inflammation and metabolic signaling intersect along the CHIEF pathway |
| PMC2895628__F5 | Mode of miRNAs that regulate adipogenesis by modulating the canonical Wnt/Beta-catenin signaling pathway |
| PMC2895650__F1 | Multi-Variant Pathway Association Analysis Reveals the Importance of Genetic Determinants of Estrogen Metabolism in Breast and Endometrial Cancer Susceptibility |
| PMC2895966__F2 | Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target |
| PMC2896553__F6 | DISTINCT SPECTRUM OF COPY NUMBER ABERRATIONS IN PAEDIATRIC HIGH GRADE GLIOMAS |
| PMC2896632__F1 | Signaling pathway of the KRAS protein |
| PMC2896660__F2 | Placing datasets into a functional context using pathway analysis |
| PMC2896848__F2 | Alternate and peripheral androgen synthesis pathways |
| PMC2896868__F2 | Toll-like receptors in kidney disease |
| PMC2896874__F11 | Schematic overview of MAPK-regulated processes that are thought to couple light to the SCN clock during the early night |
| PMC2896911__F8 | Regulatory network that links the activities of an ensemble of transcriptional regulators, signaling components and survival factors in developing B cells into a common pathway |
| PMC2896914__F2 | Multiple genes involved in interferon production and regulation are associated with risk for lupus |
| PMC2896944__F3 | Hsp90 shelters aberrant neuronal proteins |
| PMC2896964__F1 | Schematic representation of the possible interactions between HIV-1 and the host miRNA-guided RNA silencing pathway |
| PMC2897739__F1 | Recent advances in the genetics of systemic lupus erythematosus |
| PMC2897904__F1 | Proposed mechanisms of HDACi-induced apoptosis in colon cancer cells involving the mitochondrial pathway |
| PMC2897911__F1 | Induction of Type I Interferons by Bacteria |
| PMC2897923__F1 | Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression |
| PMC2897923__F2 | Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression |
| PMC2897923__F3 | Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression |
| PMC2897958__F4 | Regulation of Lipid and Glucose Metabolism by Phosphatidylcholine Transfer Protein |
| PMC2898064__F10 | Views of predicted functional interactions |
| PMC2898064__F3 | Overlay of predicted functional interactions onto a human curated GBM pathway from the TCGA data set |
| PMC2898136__F1 | Eicosanoids and cancer |
| PMC2898136__F3 | Eicosanoids and cancer |
| PMC2898136__F6 | Eicosanoids and cancer |
| PMC2898418__F10 | Schematic pathway of IL-8-mediated NAADP formation by CD38 in LAK cells |
| PMC2898443__F1 | The eukaryotic 80 S initiation pathway |
| PMC2898451__F8 | Schematic illustration of signaling pathways involved in PDGF-mediated induction of Arc expression |
| PMC2899674__F1 | Molecular pathway for arterial, venous and lymphatic cell fate determination in vertebrate embryo |
| PMC2900152__F9 | Proposed DAP12 signaling pathway in macrophages and osteoclasts |
| PMC2900209__F6 | Inflammation Stages in the Acute Lung Injury in Mice. |
| PMC2900214__F6 | Genome Erosion in a Nitrogen-Fixing Vertically Transmitted Endosymbiotic Multicellular Cyanobacterium |
| PMC2900889__F8 | Possible fates of disulfide reduced SOD1 in the G93A/CCS mouse |
| PMC2901146__F2 | Taxol biosynthetic pathway |
| PMC2901320__F5 | CXCR4 pathway is affected in CD34+ cells from CAD patients |
| PMC2901551__F1 | mTOR signal pathway |
| PMC2901643__F2 | Putative signaling components in fungal mating interactions |
| PMC2901795__F1 | Left: the EGFR pathway; Right: inhibition of the EGFR pathway by the EGFR monoclonal antibodies |
| PMC2901811__F4 | II S and TOR-signaling pathway in Drosophila |
| PMC2901871__F7 | Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis |
| PMC2902124__F1 | TLR signalling |
| PMC2902148__F1 | VEGF signaling interactions |
| PMC2902440__F7 | Key pathway involved in MODY diabetes |
| PMC2902700__F6 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE STIMULATES THE PROLIFERATION OF COLORECTAL CANCER CELLS |
| PMC2902748__F1 | Hsp90-dependent modulation of proangiogenic signaling pathways in cancer |
| PMC2902905__F1 | Sub-Cellular and Signaling Mechanisms Underlying Polar PIN Localization.A model of regulators and pathways contributing to polar PIN localization in roots is proposed based on results discussed in this review |
| PMC2903433__F4 | Chloride Regulation in the Pain Pathway |
| PMC2903563__F7 | Glucose metabolic pathway response |
| PMC2903791__F11 | Cell signaling model for the regulation of glucose metabolism in hepatocytes by taurocholate |
| PMC2903975__F1 | TLR signalling pathways: All TLRs except TLR3 share a common initial signalling pathway through MyD88 to the IRAK1/2/4TRAF6 complex |
| PMC2904042__F2 | Concurrent deregulation of the top five canonical pathways in retinoblastoma (RB) tumors |
| PMC2904682__F1 | Schematic model of regulatory pathways involved in Mycn stabilization |
| PMC2904914__F1 | Glial cell line-derived neurotrophic factor can signal through activation of Src kinases in SSCs |
| PMC2904914__F2 | Glial cell line-derived neurotrophic factor can signal through a Ras-induced pathway in SSCs |
| PMC2905036__F2 | Schematic diagram depicting the proposed role of bone morphogenetic protein (BMP) signaling pathway, HJV, HFE, and TFR2 in iron sensing and hepcidin regulation in the liver |
| PMC2905036__F3 | Schematic diagram depicting the molecular mechanisms by which inflammation activates hepcidin transcription in the liver |
| PMC2905064__F2 | Integration of oncogenic and tumor suppressor inputs by the GLI code in cancer |
| PMC2905205__F1 | Signalling routes of copper and hydrogen peroxide |
| PMC2905230__F1 | Simplified Overview of TLR Signaling |
| PMC2905316__F2 | Involvement of the Notch signaling pathway during endocrine cell differentiation |
| PMC2905406__F10 | Illustration of GDNF signaling disruption by coated silver nanoparticles |
| PMC2905627__F7 | Schematic diagram demonstrates intracellular signaling events in the Ras/ERK1/2 pathway as well as the upstream and downstream cascades activated by GDNF in the C18-4 cells |
| PMC2905744__F3 | Novel targets for the treatment and palliation of gastrointestinal neuroendocrine tumors |
| PMC2906263__F3 | Suppression of IFN-induced Jak-STAT signaling in hepatitis C |
| PMC2906289__F3 | Schematic view of glycerolipid biosynthesis pathways integrated with microarray data |
| PMC2906469__F3 | Progressive inactivation of GSK3B may promote increased anti-apoptosis and oral cancer |
| PMC2906469__F4 | Targeting GSK3B pathway may be highly beneficial for curing oral cancer |
| PMC2907165__F1 | Type I IFN Signaling |
| PMC2907214__F1 | F igure 1.– |
| PMC2907250__F1 | The three top ranked pathways in this study.'Syndecan-1-mediated signaling events' from PID; (B) 'Signaling of hepatocyte growth factor (c-Met)' from BioCarta; (C) 'Growth hormone signaling pathways' from BioCarta |
| PMC2907396__F3 | Genome-Wide Expression Profiling Deciphers Host Responses Altered during Dengue Shock Syndrome and Reveals the Role of Innate Immunity in Severe Dengue |
| PMC2907574__F4 | Inhibition of host signalling pathways by VACV members of A46 and related families |
| PMC2907698__F4 | An example of combined analysis of three identified regulatory modules |
| PMC2907713__F5 | Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways |
| PMC2907875__F8 | Estrogen and Xenoestrogens in Breast Cancer |
| PMC2908016__F2 | Therapeutic HPV vaccines |
| PMC2908393__F3 | Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy |
| PMC2908393__F4 | Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy |
| PMC2908393__F5 | Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy |
| PMC2908475__F2 | The intracellular signaling network regulating T-cell trafficking and differentiation |
| PMC2908510__F3 | Normal and Cancer-Related Functions of the p160 Steroid Receptor Coactivator (SRC) Family |
| PMC2908542__F8 | Sirtuin 3, a New Target of PGC-1A, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis |
| PMC2908610__F1 | Death receptor pathway via Fas ligand and Fas receptor |
| PMC2908618__F7 | Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomics Analysis |
| PMC2908764__F3 | Molecular cues controlling the pathway choices at the Drosophila and vertebrate midline |
| PMC2908766__F2 | PI3K dependent signal pathway |
| PMC2908768__F4 | Cytokine signaling through the Jak/Stat pathway in mammary gland development |
| PMC2909029__F2 | A possible mechanism for the inhibitory effect of p66Shc on mitogenic signaling |
| PMC2909319__F9 | Model: a Src-Tks5-Nck signalling pathway in invadopodia |
| PMC2909359__F8 | Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest |
| PMC2909379__F3 | Hox Genes and Regional Patterning of the Vertebrate Body Plan. |
| PMC2909548__F3 | Protein-protein interaction comprising the transforming growth factor B signaling pathway |
| PMC2909548__F4 | Protein-protein interaction maps comprising the transforming growth factor B signaling pathway of transcription factors associated with liver cell proliferation |
| PMC2909599__F1 | GLP-1 acts by means of the GLP-1-R to stimulate adenylyl cyclase (AC), and thereby cAMP production, and to activate the cAMP-binding proteins PKA and Epac |
| PMC2909654__F5 | Examples of human disease phenotype correlations in the absence of metabolite sharing but detected by flux correlations |
| PMC2909662__F1 | Signaling pathways of TLR4 |
| PMC2910015__F4 | General view of the species-specific regulation of histone homeostasis |
| PMC2910227__F3 | Cellular Functions of Transient Receptor Potential channels |
| PMC2910246__F8 | Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: Apoptosis through the formation of 3-hydroxykynurenine |
| PMC2910728__F6 | Absence of Inhibin Alpha and Retinoblastoma Protein Leads to Early Sertoli Cell Dysfunction |
| PMC2910789__F1 | Selected IGF-axis genes that encode core components of IGF-axis upstream the PI3K/AKT/mTOR and RAS/MAPK/ERK pathway |
| PMC2910898__F1 | During normoxia, HIF-1A is rapidly degraded by the ubiquitin-proteasome pathway |
| PMC2911016__F1 | "Go upstream, young man": lessons learned from the p38 saga. |
| PMC2911128__F1 | PI3K/Akt/mTOR signaling pathway |
| PMC2911411__F3 | Network analysis of BAL proteome changes under baseline conditions |
| PMC2911442__F5 | WRN participates in the regulation of PCNA mono-ubiquitination and subsequent TLS through interaction with PCNA |
| PMC2911501__F2 | gp130-dependent cytokines promote axon regeneration and SOCS3 act as a critical negative regulator of the signaling pathway |
| PMC2911501__F3 | PTEN-regulated signaling pathway |
| PMC2912031__F4 | Reciprocal inhibition mechanism by TGFB and IFNG |
| PMC2912204__F1 | PIK3CA and KRAS mutations predict for response to everolimus therapy: now that's RAD001 |
| PMC2912210__F1 | Targeting the mitogen-activated protein kinase pathway: physiological feedback and drug response |
| PMC2912554__F6 | Tumor suppressor pathways control Mdm2 function |
| PMC2912609__F2 | Currently available therapies targeting EGFR signaling pathway |
| PMC2912804__F7 | Role of PGE2 in bridging TLR4 signaling and intestinal tumorigenesis |
| PMC2912833__F3 | Generation of a biological network of genes of the most significant Canonical Pathways for the EF·CIF (Il10-/- vs |
| PMC2912833__F4 | Generation of a biological network of genes of the most significant Canonical Pathways for the Il10-/- (EF·CIF vs |
| PMC2913069__F1 | Interconnected pathways that cause bone marrow failure |
| PMC2913337__F2 | Cross talk of the Nodal/Cripto-1 signaling pathway with Wnt, hypoxia, Notch, Oct-4, and Nanog signaling pathways |
| PMC2913378__F3 | Signaling pathways that mediate actomyosin-dependent disruption of the epithelial barrier in inflammation |
| PMC2913455__F7 | E-selectin-mediated slow rolling |
| PMC2913512__F2 | G Protein-Coupled Receptor 87: a Promising Opportunity for Cancer Drug Discovery |
| PMC2913631__F3 | Schematic model of crosstalk between PPARG and Wnt-5a signaling in MSC |
| PMC2913704__F6 | TGFB1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation |
| PMC2913986__F6 | Gene Chip analysis reveal SOX11-induced regulation of Rb-E2F and TGFB signaling pathways |
| PMC2914056__F6 | Pathway packaging of the 'biopolymer metabolic process' module |
| PMC2915454__F4 | Pathways underlying absorption of cholesterol from the intestinal lumen and its delivery to the liver |
| PMC2915629__F4 | Identification of RON-targeting genes |
| PMC2915669__F6 | Model showing the interorganellar flow of acetyl units in C |
| PMC2915700__F6 | Schematic representation of the line of events by which HA modulates the leukocyte-EC interaction |
| PMC2915738__F7 | Metalloproteinase-dependent cross-talk between the PDGFRB and the EGFR/ERK1/2 signaling pathway |
| PMC2915874__F3 | ER-activated postreceptor mechanisms |
| PMC2916219__F5 | A model for regulation pathways responsible for RN and AM symbioses |
| PMC2916406__F7 | New model for a novel role of p38 MAPK in the DNA damage response in cancer cells |
| PMC2916838__F8 | NPRL2 Sensitizes Human Non-Small Cell Lung Cancer (NSCLC) Cells to Cisplatin Treatment by Regulating Key Components in the DNA Repair Pathway |
| PMC2917029__F8 | Molecular pathway initiated by P4 signaling in BPBC cells |
| PMC2917144__F1 | Toll-like receptor signaling pathway |
| PMC2917385__F1 | Tumor Microenvironment in Non-Small Cell Lung Cancer |
| PMC2917731__F1 | Intracellular signaling of FIP1L1/PDGFRA+ (F/P) cells |
| PMC2917906__F1 | HIF-1A and HIF-2A have different functions in the cartilage |
| PMC2918404__F8 | Osteogenic Transcription Factor Runx2 Regulates Components of the Fibroblast Growth Factor/Proteoglycan Signaling Axis in Osteoblasts |
| PMC2918459__F1 | Biosynthetic pathway of ω3 and ω6 polyunsaturated fatty acids (PUFAs) |
| PMC2918880__F1 | Schematic depiction of selected core elements of the unfolded protein response (UPR), featuring the components measured herein (; ; ; ) |
| PMC2919048__F7 | Comparative Analysis of Extra-Embryonic Endoderm Cell Lines |
| PMC2919048__F8 | Comparative Analysis of Extra-Embryonic Endoderm Cell Lines |
| PMC2919149__F7 | Targeting HIF activation pathway for cancer therapy |
| PMC2919275__F2 | PD-1 Pathway in Tolerance and Autoimmunity |
| PMC2919275__F3 | PD-1 Pathway in Tolerance and Autoimmunity |
| PMC2919366__F4 | STAT3 signaling pathway |
| PMC2919370__F4 | Fanconi Anemia Proteins and Endogenous Stresses |
| PMC2919646__F2 | Cystic Kidney Disease: the Role of Wnt Signaling |
| PMC2919655__F3 | Diversity in Post-Transcriptional Control of Neutrophil Chemoattractant Cytokine Gene Expression |
| PMC2919952__F1 | Scheme of basic metabolic pathways and energy conservation in C |
| PMC2920202__F2 | Spatial-temporal signals determine the fate of activated CD8+ T cells |
| PMC2920345__F3 | Viral tricks to grid-lock the type I interferon system |
| PMC2920482__F1 | Detection of WNV and activation of IFNA/B genes and ISG according to the 2-step model |
| PMC2920636__F5 | Molecular networks over-represented by E |
| PMC2920679__F1 | Regulation of mammalian target of rapamycin (mTOR) signaling functions |
| PMC2921023__F7 | Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin |
| PMC2921074__F1 | Modulating immune function and controlling inflammation |
| PMC2921082__F1 | Adenosine monophosphate-activated protein kinase pathway in hepatic fuel metabolism |
| PMC2921082__F4 | Dual regulation of fuel metabolism and cell viability by adenosine monophosphate-activated protein kinase |
| PMC2921256__F1 | Biology of the von Hippel-Lindau/hypoxia-inducible factor (VHL-HIF) axis in the setting of hypoxia or a mutation or aberration of the VHL gene product |
| PMC2921274__F2 | Eph receptors and ephrins in cancer: bidirectional signaling and beyond |
| PMC2921274__F4 | Eph receptors and ephrins in cancer: bidirectional signaling and beyond |
| PMC2921475__F1 | Cord Blood Genomic Analysis Highlights the Role of Redox Balance |
| PMC2921576__F1 | Schematic representation of hepatic methionine metabolism |
| PMC2921605__F1 | PIK3/Akt/mTOR Pathway |
| PMC2921612__F1 | Molecular Diagnosis and Therapy of Kidney Cancer |
| PMC2921957__F4 | Summary of factor H recognition functions and interactions |
| PMC2921989__F1 | Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein |
| PMC2921989__F2 | Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein |
| PMC2922045__F1 | TLR AGONISTS: Are They Good Adjuvants? |
| PMC2922222__F1 | Conserved ATR→CHK1 checkpoint signaling pathway in eukaryotes (, ) |
| PMC2922475__F1 | CD73: A novel target for cancer immunotherapy |
| PMC2922498__F2 | Schematic for DSB repair by HR and NHEJ pathways |
| PMC2922518__F1 | Schematic illustration depicting the cellular pathways that lead to eIF4E activation and phosphorylation by Mnk1/2 |
| PMC2922838__F2 | Gene expression profiling in whole blood of patients with coronary artery disease |
| PMC2923187__F8 | Hybrid Models Identified a 12-Gene Signature for Lung Cancer Prognosis and Chemoresponse Prediction |
| PMC2923204__F2 | Post-synaptic BDNF-TrkB Signaling in Synapse Maturation, Plasticity and Disease |
| PMC2923369__F2 | Auto-layout of 'Caffeine (C) neighborhood' based on Ingenuity curated finding (IPA, Ingenuity® Systems) |
| PMC2923430__F9 | Immune Response |
| PMC2923453__F1 | Molecular Pathways: Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma |
| PMC2923738__F4 | Human erythrocyte metabolism modeled using detailed enzyme rate equations |
| PMC2923990__F7 | Model for C |
| PMC2924379__F2 | Examination of Apoptosis Signaling in Pancreatic Cancer by Computational Signal Transduction Analysis |
| PMC2924553__F1 | BMP signal transduction |
| PMC2924648__F3 | Directed cell migration |
| PMC2924816__F1 | Quantification of Beta-Catenin Signaling Components in Colon Cancer Cell Lines, Tissue Sections, and Microdissected Tumor Cells using Reaction Monitoring Mass Spectrometry |
| PMC2924908__F2 | Complement - a key system for immune surveillance and homeostasis |
| PMC2924916__F2 | P-values for testing association of the genes within the MAPK signaling pathway with RA in WTCCC studies |
| PMC2924916__F3 | P-values for testing association of the genes within the MAPK signaling pathway with RA in NARAC studies |
| PMC2925029__F3 | The IFN-λ receptor signaling pathway |
| PMC2925066__F1 | Major Apoptotic pathways |
| PMC2925528__F1 | Summary of the systemic involvement of choline-containing species and their potential relationship with inflammatory processes |
| PMC2926258__F3 | Schematic representation of the role of T cells in the mechanism by which intermittent PTH treatment stimulates bone formation |
| PMC2926749__F4 | Proposed model for MALT1 function in NFKB activation |
| PMC2926929__F1 | The Effects of EPA, DHA, and Aspirin Ingestion on Plasma Lysophospholipids and Autotaxin |
| PMC2926987__F3 | Reconstructed antioxidant regulation pathway of detoxifying proteins |
| PMC2927346__F1 | Irinotecan pharmacogenomics |
| PMC2927527__F2 | "Mens Sana In Corpore Sano": Exercise and Hypothalamic ER Stress |
| PMC2927928__F3 | Molecular pathways involved in pancreas and liver differentiation from hES cells |
| PMC2927952__F3 | Insulin signaling pathway from PathVisio |
| PMC2928307__F1 | Plastids play a central role in the generation of wounding and herbivory induced signals |
| PMC2928401__F8 | Identification of Primary Gene Targets of TFAP2C in Hormone Responsive Breast Carcinoma Cells |
| PMC2928541__F2 | Wnt signaling pathway |
| PMC2928642__F8 | The PA-mediated activation of mTORC1 signaling |
| PMC2928685__F1 | Schematic diagram of the interaction of HH signalling on p53 and Nanog |
| PMC2928709__F4 | Observation of the differentially expressed genes on the human cell cycle (A) and transforming growth factor beta (TGFB) signaling pathways (B) modified from Kyoto Encyclopedia of Genes and Genomes (KEGG) (www.genome.jp/kegg/kegg1.html) |
| PMC2928711__F9 | Leptin upregulates VEGF in breast cancer via canonic and non-canonical signaling pathways and NFKB/HIF-1A activation |
| PMC2928803__F3 | Gene Expression Model for the Preferential Galactose Uptake in Yeast Cells |
| PMC2928959__F6 | Hypothetical model for EGFR-dependent loss of cell polarity and activation of Wnt signaling in CS-exposed human airway epithelium |
| PMC2929006__F3 | Genetic basis of kidney cancer: a metabolic disease |
| PMC2929006__F5 | Genetic basis of kidney cancer: a metabolic disease |
| PMC2929310__F3 | Transcript abundance patterns in Kawasaki disease patients with IVIG resistance |
| PMC2929310__F6 | Transcript abundance patterns in Kawasaki disease patients with IVIG resistance |
| PMC2929604__F1 | Role of TLR4 in hepatic I/R injury |
| PMC2929667__F6 | Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation |
| PMC2929731__F8 | cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways |
| PMC2929951__F8 | Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome |
| PMC2930200__F1 | Molecular machinery of myelin gene transcription in Schwann cells |
| PMC2930269__F2 | CSCs drug resistance methodology |
| PMC2930641__F2 | MAPK Signaling Pathway |
| PMC2930664__F1 | One-Carbon Metabolism and Alzheimer's Disease: Focus on Epigenetics |
| PMC2930670__F2 | Iron redox cycling in aerobic iron metabolism |
| PMC2930673__F1 | Cellular iron processing |
| PMC2930673__F2 | Transport of heme synthesis intermediates and heme in metazoans |
| PMC2930805__F1 | Metabolic signaling pathway of candidate pathway |
| PMC2930807__F4 | Gene pathway analysis |
| PMC2930854__F10 | Ephrin-A5 and EphA5 Interaction Induces Synaptogenesis during Early Hippocampal Development |
| PMC2931413__F1 | Hermaphroditism in Caenorhabditis nematodes.(A) The Caenorhabditis hermaphrodite gonad |
| PMC2932530__F9 | Redox regulation of the PI3K/Akt signaling pathway |
| PMC2932677__F1 | Diversity and Plasticity of Th Cell Types Predicted from Regulatory Network Modelling |
| PMC2932783__F1 | Targeting of signaling pathways by arsenic trioxide in chronic lymphocytic leukemia cells |
| PMC2933174__F6 | Model depicting a novel mechanism by which cetuximab induces autophagy |
| PMC2933206__F7 | Hypothetical model of how Str1 may affect cellular behavior via the Beta-catenin/LEF signal transduction pathway |
| PMC2933224__F1 | Gradient Descent Optimization in Gene Regulatory Pathways |
| PMC2933224__F3 | Gradient Descent Optimization in Gene Regulatory Pathways. |
| PMC2933224__F4 | Gradient Descent Optimization in Gene Regulatory Pathways |
| PMC2933229__F3 | The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas |
| PMC2933269__F1 | Activin signaling regulates transcription of the FSHB gene |
| PMC2933389__F9 | Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications. |
| PMC2933544__F3 | Proposed model of epidermal growth factor receptor (EGFR) aberrant activation and trafficking in the setting of cigarette smoke (CS) |
| PMC2933570__F1 | Coordinated upregulation of cytoprotective genes occurs as a result of Nrf2 activation |
| PMC2933676__F3 | The canonical Wnt signaling pathway |
| PMC2933688__F3 | EGFR signaling and NHEJ |
| PMC2933845__F4 | Genistein inhibits critical pathways in cancer invasion |
| PMC2933905__F2 | Distinct functions for TPPII in the nucleus and cytosol |
| PMC2934757__F1a | Defining the pathway to insulin-like growth factor system targeting in cancer |
| PMC2934775__F8 | Fluxmap of the glycolysis, penthose phosphate pathway, and citric acid cycle for the experiment where carbon-limiting medium is changed to nitrogen-limiting medium at time zero |
| PMC2934775__F9 | Fluxmap of the glycolysis, penthose phosphate pathway, and citric acid cycle for the experiment where nitrogen-limiting medium is changed to carbon-limiting medium at time zero |
| PMC2934865__F2 | Hypothetical model for SUMO regulation in NFKB pathway |
| PMC2935201__F3 | Platelets, Petechiae, and Preservation of the Vascular Wall |
| PMC2935335__F1 | The highly simplified PI3K/Akt and MAP kinase pathways in thyroid cancer |
| PMC2935632__F7 | Schemes of the opposing responses of p53 after lupulone treatment in SW620 and SW480 cells |
| PMC2935989__F2 | GRK2 interactome involved in cell migration |
| PMC2935989__F3 | GRK2 interactome involved in the modulation of cell cycle progression |
| PMC2936065__F2 | The Lrp5-dependent regulation of bone formation through inhibition of tph1 expression and 5-HT synthesis in enterochromaffin cells |
| PMC2936296__F2 | RIG-I signalling pathway |
| PMC2936527__F1 | Synthesizing and Salvaging NAD+: Lessons Learned from Chlamydomonas reinhardtii |
| PMC2936760__F5 | Signaling pathways described in ARPE19 cells |
| PMC2937064__F1 | Leptin, IGFBP3, and rapamycin suppress the IGF-1 signaling pathway to preserve naïve T cells and promote longevity |
| PMC2937064__F3 | CD28 signaling pathway in T cells is equivalent to the IGF-1 pathway in the whole organism |
| PMC2937064__F4 | Reactive oxygen species, UV light or other genotoxic stresses, that induce DNA damage, principally, double-stranded breaks, is detected by the MRE11-RAD50-NBS1 complex, which in turn activates ATM |
| PMC2937358__F1 | ERAlpha-Negative and Triple Negative Breast Cancer: Molecular Features and Potential Therapeutic Approaches |
| PMC2937452__F1 | Model of pyrimidine synthesis and salvage pathways in Toxoplasma gondii |
| PMC2937518__F4 | Overview of predicted carbohydrate uptake and metabolism systems in bifidobacteria |
| PMC2937585__F1 | Folate metabolic pathway |
| PMC2938013__F9 | Dixdc1 is a critical regulator of DISC1 and embryonic cortical development |
| PMC2938097__F6 | TNF/Fas/TRAIL signaling pathway |
| PMC2938150__F3 | Comparison of fluxes of central carbon metabolism determined by MFA and predicted from a genome-scale metabolic model |
| PMC2938197__F1 | Predicted hydroxy/hydroperoxy wybutosine biosynthesis pathway and domain architecture of key enzymes involved in its synthesis |
| PMC2938460__F1 | Proposed signaling pathway by which all three PPAR isoforms exert anti-apoptotic actions via 14-3-3E upregulation |
| PMC2938637__F2 | Current model of early symbiotic signaling pathways |
| PMC2938833__F2 | Actin-cytoskeleton signaling pathway and the candidate genes involved in colorectal cancer progression in patients with ulcerative colitis |
| PMC2938833__F3 | Pfn gene neighborhood and its interacting pathway |
| PMC2939005__F1 | Two major insulin signaling pathways |
| PMC2939232__F10 | Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2) |
| PMC2939266__F3 | Dopamine-sensitive signaling via adenylyl cyclase (AC), phospholipase C (PLC), and phosphatidylinositol-3-kinase (PI3K) systems |
| PMC2939298__F1 | Schematic diagram of androgen biosynthesis |
| PMC2939308__F1 | Activation of PPARG and PTEN Cascade Participates in Lovastatin-mediated Accelerated Differentiation of Oligodendrocyte Progenitor Cells |
| PMC2939362__F1 | Domain organization of proteins in the Hh signaling pathway |
| PMC2939392__F2 | Proposed inhibitory mechanisms of SOCS1 on TLR signaling |
| PMC2939393__F1 | The Fe-S biogenesis proteins, ISCA and C1orf69 (Iba57 homologue), may impact heme synthesis by affecting the production of succinyl-CoA, a substrate of heme synthesis |
| PMC2939609__F3 | Molecular interactomes and sub-networks associated with tumor cell susceptibility to arsenic trioxide |
| PMC2939633__F1 | Chk1 suppressed death pathways |
| PMC2939656__F4 | Complement/Coagulation pathway activation |
| PMC2939720__F1 | Viral hijacking of the host ubiquitin system to evade interferon responses |
| PMC2940266__F1 | Phosphatase and Tensin Homologue deleted on Chromosome 10: Extending its PTENtacles |
| PMC2940266__F2 | Phosphatase and Tensin Homologue deleted on Chromosome 10: Extending its PTENtacles |
| PMC2940478__F3 | Web-accessible GnRHR pathway navigator |
| PMC2940764__F2 | Differences in Muscle and Adipose Tissue Gene Expression and Cardio-Metabolic Risk Factors in the Members of Physical Activity Discordant Twin Pairs |
| PMC2940871__F3 | Metabolic reactions involving the PGM2 (adapted from []) |
| PMC2940983__F1 | Histone GH2AX and Poly(ADP ribose) as Clinical Pharmacodynamic Biomarkers |
| PMC2941735__F2 | Targeting Non-Homologous End-Joining Through Epidermal Growth Factor Receptor Inhibition: Rationale and Strategies for Radiosensitization |
| PMC2942073__F1 | Genetics of Psychosis in Alzheimer Disease: A Review |
| PMC2943133__F2 | Toll-like receptor (TLR) signalling is mediated by at least two distinct pathways |
| PMC2943291__F6 | Proposed scheme of the molecular mechanism underlying LPCAT2 activation |
| PMC2943318__F7 | Ulk3 function in Shh signaling pathway |
| PMC2943488__F1 | Schematic of the drug- and cytokine-induced hepatocellular death signaling network, curated from literature references-, - |
| PMC2943518__F7 | Diagram of a putative LPS-induced PTP/LITAF/TNF signaling pathway |
| PMC2943748__F6 | SENP1 participates in the dynamic regulation of Elk-1 SUMOylation |
| PMC2943859__F5 | Death receptor signaling and its interdigitation with the mitochondrial pathway of apoptosis |
| PMC2943859__F9 | TNF-R1 signaling pathways |
| PMC2943975__F1 | TOR signaling never gets old: Aging, longevity and TORC1 activity |
| PMC2944186__F1 | Convergence between Wnt and EGFR pathways |
| PMC2944409__F6 | Calcium Signaling Pathway (KEGG, Kanehisa Laboratory in Kyoto University, Japan) with vinclozolin altered genes indicated |
| PMC2944409__F7 | Gene interaction sub-network of shortest connections to common targets for the 36 candidate regulatory genes obtained by global literature analysis (Pathway Studio 7.0, Ariadne Genomics Inc., Rockville MD) |
| PMC2944809__F5 | Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence |
| PMC2944875__F2 | Gene Expression Study of Monocytes/Macrophages during Early Foreign Body Reaction and Identification of Potential Precursors of Myofibroblasts |
| PMC2945029__F6 | Pathways and networks related to chondrocyte proteins identified by proteomics as altered by GS and/or CS |
| PMC2945208__F1 | KEEPING AN EYE ON RETINOBLASTOMA CONTROL OF HUMAN EMBRYONIC STEM CELLS |
| PMC2945208__F3 | KEEPING AN EYE ON RETINOBLASTOMA CONTROL OF HUMAN EMBRYONIC STEM CELLS |
| PMC2945462__F1 | Complement cascade is comprised of the Classical, Alternative, and Mannose Binding Lectin pathways |
| PMC2945552__F11 | Proposed signaling pathway modulated by TH2-3 in LPS-induced RAW264.7 cells |
| PMC2945562__F8 | Summary of signaling pathways for cPLA2A activation and eicosanoid production stimulated by engagement of C |
| PMC2945668__F1 | TLR7/9 Signaling pathway leading to the production of proinflammatory cytokines and type I IFN |
| PMC2945784__F2 | Cancer signaling pathways affected within the tumor |
| PMC2945811__F1 | FA-regulated ICL repair |
| PMC2945950__F1 | BCR signaling pathway |
| PMC2945950__F2 | ERBB signaling pathway |
| PMC2945950__F5 | Moral graph Dm obtained from BCR pathway |
| PMC2945950__F6 | Triangulated graph Dt obtained from BCR pathway |
| PMC2946515__F3 | Mutant epidermal growth factor receptor, EGFRvIII, promotes cell survival and proliferation by preferential signaling through the phosphotidyinositol-3-kinase (PI3K) pathway |
| PMC2946543__F1 | The mitochondrial fatty acid beta-oxidation pathway |
| PMC2946555__F2 | Merlin, a "Magic" Linker Between the Extracellular Cues and Intracellular Signaling Pathways that Regulate Cell Motility, Proliferation, and Survival. |
| PMC2946881__F1 | Regulation of adipogenesis by canonical Wnt signaling cascade |
| PMC2947178__F8 | Model for the Coordinated Action of the Mating Types to Regulate Different Stages of Pathogenic Development of U |
| PMC2947191__F1 | Transforming growth factor beta (TGFB) family cell signaling pathway |
| PMC2947752__F7 | The role of PDGF signaling in the PrE lineage of the mouse blastocyst |
| PMC2947794__F1 | Examination of Association to Autism of Common Genetic Variation in Genes Related to Dopamine |
| PMC2947835__F2 | Membrane proximal intracellular signals at the IS versus the HIV VS |
| PMC2947987__F3 | Genome of a Pathogenic Rhodococcus: Cooptive Virulence Underpinned by Key Gene Acquisitions |
| PMC2948187__F1 | Altered cellular pathways and processes in tumours |
| PMC2948275__F1 | Putative functions of caspase-2 |
| PMC2948292__F1 | Potential roles of BLM and RECQ5 in sister chromatid exchange regulation |
| PMC2948329__F2 | TSC1/2 integrates multiple signals to control cell growth and proliferation |
| PMC2948497__F6 | cDNA Microarray Gene Expression Profiling of Hedgehog Signaling Pathway Inhibition in Human Colon Cancer Cells |
| PMC2948541__F5 | Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders |
| PMC2948618__F3 | 3rd US-EU Workshop Systems level understanding of DNA damage responses |
| PMC2948663__F1 | Molecular and genetic events in mammalian sex determination and differentiation |
| PMC2949081__F1 | Summary of the RAS incorporating the Ang peptide family and physiological effects mediated via ATR subtypes |
| PMC2949087__F5 | Mitochondria and neuroplasticity |
| PMC2949127__F3 | HMGB1 signaling events mediated by RAGE and TLR2/4 and therapeutic strategies for cerebral ischemia |
| PMC2949386__F6 | Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity |
| PMC2949446__F1 | Luteolin and gefitinib regulation of EGF Signaling Pathway and Cell Cycle Pathway genes in PC-3 human prostate cancer cells |
| PMC2949481__F2 | Insulin, IGF-I and IGF-II signaling through the IGF-IR |
| PMC2949529__F2 | O-GlcNAc Signaling: A Metabolic Link Between Diabetes and Cancer? |
| PMC2949647__F1 | Structure and signaling machinery of the Met receptor |
| PMC2949659__F1 | Tamoxifen metabolic pathway |
| PMC2949723__F3 | Eicosanoid signaling pathway from Ingenuity Pathway Analysis software |
| PMC2949777__F5 | JAK/STAT pathway in infected EPCs |
| PMC2949778__F1 | Folate metabolic pathway |
| PMC2949900__F4 | Cell Cycle Pathway: Differentially expressed genes involved in the cell cycle are shown in pink |
| PMC2950025__F1 | Models of mitotic exit in yeast |
| PMC2950451__F3 | Metabolic flux distribution through branching areas of the central metabolism of MG1655 and ECOM4LA cell lines |
| PMC2950652__F2 | Pioneer Round of Translation: Features and Functions |
| PMC2950751__F9 | Summary schematic illustrating the adaptations of select genes of the IGF-1/PI3K/Akt pathway involved in protein synthesis and degradation analyzed in the plantaris muscle |
| PMC2951022__F1 | Toll-like receptor (TLR) signaling pathways |
| PMC2951227__F7 | Hypothetical model for Rad18-dependent activation of the FA pathway in response to bulky DNA adducts |
| PMC2951593__F3 | Biological association networks of the significantly downregulated genes associated with the ontological "regulation of transcription" (A) and "MAPK signaling pathway" (B) classes |
| PMC2951628__F1 | Inflammation Joins the "Niche" |
| PMC2951839__F1 | Lower Succinyl-CoA:3-ketoacid-CoA Transferase (SCOT) and ATP Citrate Lyase In Pancreatic Islets of A Rat Model of Type 2 Diabetes: Knockdown of SCOT Inhibits Insulin Release In Rat Insulinoma Cells |
| PMC2952128__F4 | Functional gene networks identified using IPA from differentially expressed genes between control and 300 nM reversine-treated annulus fibrosus cells |
| PMC2952191__F2 | mTOR signaling pathway |
| PMC2952341__F1 | Alteration of Notch signaling in skeletal development and disease |
| PMC2952389__F1 | Outline of T-cell development pathway from bone marrow to the thymus |
| PMC2952492__F1 | Regulation of neo-vascularization by SDF-1 |
| PMC2952500__F1 | Schematic diagram showing the results of ras activation by Grb2 |
| PMC2953155__F5 | Model schematic of Nipah virus-triggered DC immune response mechanisms and antagonist activity of the response |
| PMC2953449__F3 | Different effects of gut- and brain-derived serotonin on the osteoblast |
| PMC2953497__F9 | Tumor Necrosis FactorA Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells |
| PMC2953497__F10 | Tumor Necrosis FactorA Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells |
| PMC2953617__F2 | JS genes implicated in the Shh, Wnt, and PDGFA signaling pathway |
| PMC2953915__F7 | Model of E2F2-mediated regulation of the Ahr pathway |
| PMC2954189__F1 | Simplified scheme of the double-edged role of Akt in tumor development |
| PMC2954288__F10 | Hypothetical model for SWAP-70 function in mast cell FcERI signaling |
| PMC2954312__F2 | Crosstalk between the three distinct oscillators that function in the mouse PSM.(a) Schematic diagram of a signalling and a responding cell in the mouse PSM, detailing cyclic genes of the Notch, Fgf and Wnt pathways |
| PMC2954716__F4 | Developmental Programming: Differential Effects of Prenatal Testosterone Excess on Insulin Target Tissues. |
| PMC2954727__F1 | Working model of the effects of E2 on cell migration |
| PMC2954851__F2 | Protein serine/threonine phosphatases in the DNA damage response pathway |
| PMC2955136__F3 | Highly expressed proteins in MII oocytes |
| PMC2955136__F4 | Highly expressed proteins in zygotes |
| PMC2955448__F1 | Pathogenesis of prostate cancer: from molecular to metabolic alterations |
| PMC2955614__F5 | Novel molecular regulation of Wnt/Beta-catenin pathway |
| PMC2955618__F6 | Runx2-regulated cancer-related gene network |
| PMC2955764__F1 | Sonic hedgehog signaling pathway |
| PMC2955882__F4 | ENaC and ASL volume regulation |
| PMC2955921__F2 | Scheme summarizing the differential effect of PARP-1 inhibition versus silencing on SSB repair via the BER pathway |
| PMC2955993__F1 | Complement and Periodontitis |
| PMC2955993__F3 | Complement and Periodontitis |
| PMC2955995__F1 | Targeting Notch signaling pathway to overcome drug-resistance for cancer therapy |
| PMC2956014__F2 | Neutrophil apoptosis |
| PMC2956082__F6 | Simple diagram of FTY720 action in the mitochondria mediated apoptotic pathway |
| PMC2956119__F1 | This figure shows the two distinct but ultimately converging apoptosis signaling pathways in mammals |
| PMC2956119__F2 | The many roles of FAS receptor signaling in the immune system. |
| PMC2956119__F3 | The many roles of FAS receptor signaling in the immune system. |
| PMC2956378__F7 | Thrombin-induced ET-1 secretion in RPE is rho/ROCK1/2 dependent |
| PMC2956608__F1 | Inhibition of the type I interferon (IFN) pathway of Kaposi's sarcoma-associated herpesvirus (KSHV) |
| PMC2956794__F1 | Targeting DNA repair proteins for cancer treatment |
| PMC2956880__F4 | Schematic diagram showing the interaction of the p75NTR and TrkB signaling pathways |
| PMC2957472__F3 | Helicobacter pylori: gastric cancer and beyond |
| PMC2957678__F1 | Schematic view of HMGB1 signal transduction |
| PMC2957845__F6 | Scheme of the Wnt signalling pathway including proteins from the RT-PCR array |
| PMC2957893__F3 | Genes in one pathway have complex "net" interactions, which should be taken into consideration when analyzing proteomics/genomic data |
| PMC2958130__F5 | Intertwining Threshold Settings, Biological Data and Database Knowledge to Optimize the Selection of Differentially Expressed Genes from Microarray |
| PMC2958210__F12 | Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice |
| PMC2958230__F1 | Effect of TBCD and its Regulatory Interactor Arl2 on Tubulin and Microtubule Integrity |
| PMC2958833__F2 | Nutritional Programming in the Rat Is Linked to Long-Lasting Changes in Nutrient Sensing and Energy Homeostasis in the Hypothalamus |
| PMC2958907__F1 | Web-accessible DC pathway navigator |
| PMC2959043__F3 | Wnt/Beta-catenin signaling Ctenophore pathway |
| PMC2959101__F4 | Schematic diagram of NELL-1 signaling pathways in osteoblast cells |
| PMC2962793__F2 | Cytochrome P450 epoxygenase expression in tumor cell compartments and their potential role in cell-cell communication in the tumor stroma |
| PMC2962956__F1 | Toll-like receptor (TLR) signalling and inhibition by viral proteins |
| PMC2963059__F2 | Non-canonical Wnt pathways |
| PMC2963103__F1 | Normal biology of the VHL-HIF axis in the setting of (A) normoxia and (B) hypoxia |
| PMC2963106__F2 | VHL in clear-cell renal cell carcinoma and its relation to targeted therapy |
| PMC2963118__F2 | HRS cell and its cellular microenvironment |
| PMC2963142__F1 | TLR signaling pathway and downstream effector molecules |
| PMC2963177__F2 | Integration of non-SMAD and SMAD signaling in TGFB1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells |
| PMC2964046__F1 | Currently-known relationships among genes analyzed based on manually curated examination of the published literature within the Ingenuity Pathway Analysis® Knowledge Base |
| PMC2964177__F1 | ErbB2 cellular signaling pathways and lapatinib mechanism of action |
| PMC2964746__F4 | Selected signal transduction pathways that affect AS of transcripts of genes important in cancer |
| PMC2964873__F1 | The Siah2-HIF-FoxA2 axis in prostate cancer - new markers and therapeutic opportunities |
| PMC2964899__F1 | Schematic representation of the molecular events associated with cellular processing, lipid modification, and secretion of the SHH protein and the autocrine and paracrine actions of mature and secreted SHH protein |
| PMC2964899__F3 | Molecular events associated with the repressive effect induced by PTCH1 receptor on the SMO activity and the activation of the Hh signaling pathway mediated by the SHH protein in the primary cilium |
| PMC2964899__F5 | Cellular events and signaling elements involved in the regulation of SHH expression, GLI activation, and mediation of the Hh activation-induced cellular response |
| PMC2964899__F6 | Scheme showing the signaling elements and frequent deregulations in the Hh signaling network and potential cross-talk with the EGFR signaling pathway involved in the malignant behavior of cancer cells |
| PMC2964935__F5 | PAR Proteins: Fundamental Players in Animal Cell Polarization |
| PMC2964976__F8 | CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs |
| PMC2965188__F2 | Nrf2 cytoprotective signaling pathway |
| PMC2965566__F2 | Transcriptional control of invariant NKT cell development |
| PMC2965861__F1 | The AMPK pathway in relation to various molecules |
| PMC2966065__F1 | Chemical structure of OHyW in tRNAPhe and its biosynthetic pathway |
| PMC2966096__F7 | A hypothetical model of PAR-1 and PAR-2 activation by coagulation proteases when either EPCR or an unknown FX/FXa receptor is occupied by natural ligands |
| PMC2966110__F8 | Stbd1 participation in glycogen metabolism and Stbd1 structure |
| PMC2966327__F4 | Fumarate/nitrate response regulator network in P |
| PMC2966327__F5 | SOS response gene network in P |
| PMC2966480__F4 | E3 ubiquitin ligase activities of KEAP1 and AHR |
| PMC2966484__F3 | Activation of the NFKB signaling pathway |
| PMC2966547__F1 | Homocysteine metabolic pathways |
| PMC2966895__F2 | Complement-targeted therapeutics |
| PMC2966904__F7 | Proposed scheme of the signaling pathway by TfR2 and HFE |
| PMC2966944__F8 | Cartoon summary of expression and anatomical data, and a model for phases of A/P axis re-organization |
| PMC2967529__F8 | Model for vertebrate limb induction and outgrowth |
| PMC2967585__F9 | Mechanisms involved in alcohol-mediated suppression of type I IFN pathway in human hepatocytes |
| PMC2967651__F1 | A model for interplay between alloimmunity and autoreactivity in graft rejection |
| PMC2970576__F5 | Analysis of gene expression in CD44+/CD24- MCF-7/ADR cell population by TaqMan Low-Density Array and Ingenuity Pathway analysis |
| PMC2970638__F8 | Up-regulation of Paxillin and Focal Adhesion Signaling follows Dystroglycan Complex deletions and promotes a Hypertensive State of Differentiation |
| PMC2970711__F7 | Scheme of cross-talk interactions between TIM-3, Gal-9 and TLR4 signaling networks |
| PMC2971463__F3 | SLIT/ROBO pathway: a regulator of cell function with implications for the reproductive system |
| PMC2971525__F1 | DNA Damage Response (DDR) pathways in normal and malignant cells |
| PMC2972203__F8 | Reverse-Phase Phosphoproteome Analysis of Signaling Pathways Induced by Rift Valley Fever Virus in Human Small Airway Epithelial Cells |
| PMC2972271__F5 | The metabolite NAD+ oscillates in a circadian manner |
| PMC2972642__F2 | REVIEW: Oxytocin: Crossing the Bridge between Basic Science and Pharmacotherapy. |
| PMC2972700__F1 | Wnt Signaling During Fracture Repair |
| PMC2972986__F1 | Biological processes known to be stimulated in an AHR-dependent and/or AHR-independent manner by the tryptophan photoproduct FICZ |
| PMC2974067__F1 | Signaling pathways that regulate longevity in C |
| PMC2974170__F1 | Diagram of TLR signaling pathways |
| PMC2974212__F3 | Critical growth factors and signalling pathways controlling human trophoblast invasion |
| PMC2974215__F2 | TNF-dependent signalling pathways mediated through TNFR1 and TNFR2 |
| PMC2974775__F4 | Ca2+ waves activate transcription factor NFAT that in turn controls cell cycle |
| PMC2974943__F2 | Intracellular signaling pathway within cranial neural crest cells mediated by endothelin-1 (Edn1) |
| PMC2975074__F3 | Cell stress response: activation of the aggresome pathway, HSPs, and transcriptional response |
| PMC2975092__F6 | Biological interaction between glucose and genes up- (light grey) or down-regulated (white) in primary hepatic stellate cells after overexpression of Smad7 |
| PMC2975200__F9 | MyD88-induced protein accumulation pathways through SQSTM1 and HDAC6 |
| PMC2975271__F9 | Schematic model for regulation of mTOR pathway signaling through interaction of the p53 target Plk2 with TSC proteins |
| PMC2975490__F1 | Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis |
| PMC2975924__F3 | Eph/ephrin signaling regulates intestinal cell positioning and proliferation |
| PMC2975941__F2 | Classical and non-canonical NFKB pathways |
| PMC2975945__F2 | Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS |
| PMC2975945__F4 | Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS |
| PMC2976306__F7 | Changes in gene expression in central carbon metabolism (A) and ergosterol synthesis (B) |
| PMC2976339__F5 | Gene expression within cluster MCL2 is enriched in genes affecting NK cell-mediated cytotoxicity |
| PMC2976847__F1 | Cytokines, hormones or growth factors that activate Stat5 |
| PMC2976970__F3 | Protein-protein interaction map of Notch transcription modifiers |
| PMC2978002__F7 | Model demonstrating the specific apoptotic effect of SREBP-1 and FAS inhibition on GBM cells bearing EGFRvIII |
| PMC2978223__F1 | Daphnia pulex insulin and TOR signalling pathways, adapted from Drosophila melanogaster [] |
| PMC2978721__F8 | Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells |
| PMC2978917__F7 | Signaling pathway and transcription factors involved in HPR1 gene expression in cancer |
| PMC2980509__F1 | Post-Golgi sorting in conventional cell types and melanocytes: The role of HPS proteins as well as VPS33B in vesicle trafficking is demonstrated |
| PMC2980759__F1 | Examples of the inter-relationship between host, tumor, and environmental factors (pharmaco-epi-bio-genomic triad) that determine the response to tamoxifen in an individual patient (phenotype) |
| PMC2981059__F6 | HER/HER2-PI3K-Akt-NFKB-elicited pathway in prostate cancer cells |
| PMC2981097__F2 | Double strand DNA repair: Homologous recombination and Non-homologous end joining |
| PMC2981143__F1 | Folate metabolism and its contributions to physiological processes |
| PMC2981398__F1 | Role of the N-end rule pathway in RGS protein degradation |
| PMC2981456__F1 | The estrogen biosynthesis pathway |
| PMC2981460__F1 | TGFB canonical signal transduction pathway and transcriptional responses mediating TGFB growth inhibitory effects |
| PMC2981507__F2 | Therapeutic interventions for fragile X syndrome |
| PMC2981611__F1 | Wnt Signaling and Mammary Stem Cells |
| PMC2982146__F7 | Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication |
| PMC2983087__F2 | Mechanisms of double-strand break repair in somatic mammalian cells |
| PMC2983445__F2 | Growth factor signaling pathways mediating proliferation in multipotential stromal cells |
| PMC2983445__F3 | Growth factor signaling pathways mediating survival in multipotential stromal cells |
| PMC2984239__F5 | Merged network pathway analysis of proteins involved in cellular assembly and organization, cellular compromise, and protein folding that were identified in cytoplasmic fraction |
| PMC2984446__F10 | PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells |
| PMC2984459__F1 | Schematic overview of Toll-like receptor (TLR)4 signaling pathway |
| PMC2984500__F2 | Selection of miRNA implicated in the TLR4 signalling pathway |
| PMC2984599__F1 | TP53 levels determine whether CDKN1A will orchestrate irreversible senescence or quiescence |
| PMC2984612__F1 | Cellular FLICE-inhibitory protein: an attractive therapeutic target?. |
| PMC2987346__F2 | RSK signaling pathway |
| PMC2987484__F1 | Pathway analysis on differentially expressed genes |
| PMC2988350__F8 | Model of the cell survival pathway activated in mutant htt cells upon MT depolymerization |
| PMC2988681__F2 | Programming anoikis induction |
| PMC2988877__F2 | DNA Damage Response: Making it safe to play with knives |
| PMC2988877__F3 | The DNA Damage Response: Making it safe to play with knives |
| PMC2989404__F1 | Eighteen Insulin-like Growth Factor (IGF) pathway genes, circulating levels of IGF-1 and its binding protein (IGFBP-3), and risk of prostate and breast cancer |
| PMC2989631__F1 | DNA damage response (DDR) pathway |
| PMC2989646__F4 | The involvement of zinc metalloproteinases in AB metabolism |
| PMC2989686__F4 | Canonical pathways for cardiovascular disease |
| PMC2989866__F2 | The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review. |
| PMC2989879__F2 | The RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system |
| PMC2989879__F3 | The RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system |
| PMC2990064__F4 | Modeling Dose-response at Low Dose: A Systems Biology Approach for Ionization Radiation. |
| PMC2990406__F8 | A previously unknown miR-290-dependent pathway controls DNA methylation via Rbl2 and affects telomere integrity and telomere-length homeostasis |
| PMC2990476__F3 | Functional network identified by genes in the single nucleotide polymorphism (SNP) component using independent component analysis |
| PMC2990540__F1 | APC/C inhibition is regulated by signalling within the cytoplasm (a) and at the kinetochore (b) |
| PMC2990745__F1 | Examples of pathways shared by a signature hub from the Wang dataset and a signature hub from the Desmedt dataset |
| PMC2990976__F2 | TNFA signaling pathways to NFKB activation |
| PMC2991085__F2 | Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease |
| PMC2991311__F4 | Systems Biology Approach Uncovers Cellular Strategies Used by Methylobacterium extorquens AM1 During the Switch from Multi- to Single-Carbon Growth |
| PMC2991480__F5 | FC-66 expression of the Ingenuity NFKB Signaling canonical pathway |
| PMC2991513__F1 | JNK signaling pathway |
| PMC2991541__F3 | Redox-control of Matrix Metalloproteinase-1: A critical link between free radicals, matrix remodeling and degenerative disease. |
| PMC2991775__F1 | Pathways leading to the type I interferon production |
| PMC2992267__F8 | A schematic model showing the proposed biosynthetic pathway for cutin |
| PMC2992289__F5 | KLA increases mRNA expression of genes involved in sphingolipid biosynthesis |
| PMC2992472__F4 | The regulatory network of apoptosis in BCL11B and its related genes |
| PMC2992886__F3 | Genes associated with autoimmunity regulate the CD40/NFKB signaling pathway |
| PMC2992967__F2 | Sonic hedgehog (SHH) pathway |
| PMC2993245__F2 | Negative regulation of junctional stability in RPE by the PI3K-ROS circuit |
| PMC2993603__F1 | A tincture of hepcidin cures all: the potential for hepcidin therapeutics |
| PMC2993607__F1 | RB tumor suppressor: a gatekeeper to hormone independence in prostate cancer? |
| PMC2993794__F1 | Stimuli and factors involved in yeast chronological aging |
| PMC2993798__F6 | A conserved insulin signaling pathway in C |
| PMC2993855__F2 | Pathways correcting DNA polymerase errors |
| PMC2994033__F1 | Signaling complexes are induced by TNFA to mediate NFKB activation, apoptosis, and necroptosis |
| PMC2994209__F1 | HER receptors and their ligands |
| PMC2994272__F8 | Carnosol in human prostate cancer PC3 cell line |
| PMC2994781__F1 | Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis |
| PMC2995293__F2 | Immune and central nervous systems interact and contribute to the etiology and pathophysiology of cytokine-induced depression |
| PMC2995824__F1 | Regulation of muscle protein synthesis |
| PMC2996094__F11 | Proposed model of GF-mediated regulation of IGFBP-3 |
| PMC2996105__F7 | Interaction of p75NTR and TrkB signaling |
| PMC2996236__F2 | Autoinflammatory disease regulated by IL-1B (inflammasomopathies) and NFKB |
| PMC2996236__F5 | Pathogenesis of the complement-mediated autoinflammatory disease atypical hemolytic uremic syndrome |
| PMC2996483__F3 | Oncogenic Notch1 Signalling |
| PMC2996902__F1 | CoQ10 biosynthesis pathway |
| PMC2997002__F3 | MAPK signaling pathways generated by GenMAPP |
| PMC2997006__F1 | Tor pathway in the model fungi Saccharomyces cerevisiae and Schizosaccharomyces pombe |
| PMC2997007__F5 | Candidate master switch molecules and signaling pathways involved in LPS-induced inflammatory response of monocyte THP-1 cells |
| PMC2997007__F6 | Identification of putative signaling regulators for immune-modification |
| PMC2997522__F2 | Novel Therapies Against Aggressive and Recurrent Epithelial Cancers by Molecular Targeting Tumor- and Metastasis-Initiating Cells and Their Progenies. |
| PMC2997573__F1 | The current understanding of PELP1 signaling pathway |
| PMC2997602__F1 | Signaling cascade of class I and IIa HDACs in the development of cardiac hypertrophy |
| PMC2997737__F1 | AKT/MTOR pathway |
| PMC2997801__F1 | Positioning NFKB in multiple myeloma |
| PMC2998162__F2 | Schematics of the Hippo pathway in flies and mice |
| PMC2998292__F1 | Estrogen and Tamoxifen Metabolic Pathways depicted at the genomic level |
| PMC2998292__F2 | Pathway Analysis Models for the Tamoxifen (TAM) Pathway tested with data from the Placebo (P) and Tamoxifen (T) arms |
| PMC2998553__F3 | Screen shot of the user interfaceofSimmune2.0 |
| PMC2998559__F1 | Model Depicting major molecules and events in mast cell activation |
| PMC2999098__F3 | CKI members in canonical Wnt signaling |
| PMC2999229__F1 | Hypothetical model for the molecular signaling pathways of vasculogenic mimicry in tumors and anti-vasculogenic mimicry (VM) therapy strategies |
| PMC2999286__F1 | The involvement of the Unfolded Protein Response (UPR) signaling in lipid metabolism |
| PMC2999296__F2 | Toll-like recepter 4 signaling pathway modified from Wikipedia Commons |
| PMC2999341__F12 | Regulatory PathRNet Only nodes that are close to P38 MAPK Signaling pathway or "S-7" are kept (distance<3) |
| PMC2999349__F3 | Location of 2,4DNT impacted genes in the pathway association network |
| PMC2999475__F8 | Summary of metabolomic findings in Hnf1a-null mice |
| PMC2999593__F1 | Heme Biosynthetic Pathway |
| PMC2999931__F2 | Postsqualene cholesterol synthetic pathway |
| PMC3000288__F1 | Schematic representation of the As cycle in the environment and plants |
| PMC3000367__F5 | Scalable Approach for Discovering Conserved Active Subnetworks across Species |
| PMC3000610__F6 | Proposed working hypothesis |
| PMC3000836__F1 | Comparison of the DC-ATLAS Toll Like Receptor (TLR) 3 pathway with other pathway databases |
| PMC3001129__F2 | NOD-like receptor signaling beyond the inflammasome |
| PMC3001241__F1 | MHC class II antigen processing pathways containing P |
| PMC3001241__F2 | Toll-like receptor signaling pathways containing P |
| PMC3001303__F1 | mTOR signalling pathway |
| PMC3001555__F1 | Representation of the transduction pathway involved in Cd signaling |
| PMC3001886__F5 | Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response |
| PMC3001953__F2 | EGFR-mutated lung cancer: a paradigm of molecular oncology |
| PMC3002319__F1 | Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study |
| PMC3002356__F6 | Proposed model of GS-mediated apoptosis in HNSCC cells |
| PMC3003336__F4 | FLCN pathway |
| PMC3003620__F1 | PI3K/Akt signaling pathway |
| PMC3003706__F7 | Distinct B1 and B3 integrin pathways converge to regulate cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells |
| PMC3003974__F3 | Protein interaction network of highly connected proteins associated with the cardiorenal syndrome |
| PMC3004266__F10 | Active Cdk1/cyclin B1 complex on the extrinsic death pathway |
| PMC3004331__F3 | Differential host transcriptional responses within the acute-phase response pathway in r1918-infected WT, TNFRKO, and IL1RKO mice at 1, 3, and 5 dpi |
| PMC3004338__F4 | Ingenuity Pathway Analysis (IPA) of differentially expressed genes between 24 DSS and 56 uncomplicated dengue patients |
| PMC3004523__F2 | Hypothetical roles for LAB-dependent positive signaling |
| PMC3004524__F4 | Model of pri-miRNA processing and localization |
| PMC3004666__F1 | Cetuximab in the treatment of colorectal cancer. |
| PMC3004747__F1 | Fucose is on the TRAIL of colon cancer |
| PMC3004842__F2 | Flux-sum intensity in Z |
| PMC3005023__F1 | Hypoxia and hypoxia-inducible factors (HIFs): master regulators of metastasis |
| PMC3005418__F8 | Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery |
| PMC3005738__F1 | Metabolic pathway of tamoxifen |
| PMC3006043__F3 | Colorectal Cancer Molecular Biology Moves Into Clinical Practice |
| PMC3006139__F6 | Subversion of Innate Defenses by the Interplay between DENV and Pre-Existing Enhancing Antibodies: TLRs Signaling Collapse |
| PMC3006290__F1 | Proposed signaling scheme for ischemic preconditioning |
| PMC3007169__F1 | Arsenic: a potentially useful poison for Hedgehog-driven cancers |
| PMC3008185__F1 | Two-loop model of iADE |
| PMC300841__F1 | Usurpation of the Ras signaling pathway by reovirus |
| PMC3008507__F5 | A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. |
| PMC3008616__F1 | EGFR pathway and its main downstream effectors (top) |
| PMC3008633__F1 | Examples of reaction-diffusion processes in muscle |
| PMC3009535__F3 | Functional module of the CXC chemokine pathway uniquely identified by NeMo |
| PMC3009741__F3 | Bioinformatics Analysis of Macrophages Exposed to Porphyromonas gingivalis: Implications in Acute vs. Chronic Infections |
| PMC3009898__F6 | Model for an alternative Okazaki fragment-processing pathway in vivo |
| PMC3010226__F2 | Cellular and molecular scheme for an adaptive immune axis leading to acute lung disease after viral infection |
| PMC3010252__F1 | Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanisms |
| PMC3010690__F2 | Zinc metalloprotease activity in APP processing |
| PMC3010754__F1 | Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors |
| PMC3010754__F2 | Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors |
| PMC3010981__F1 | Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells |
| PMC3011046__F2 | FAS generates an endogenous ligand for PPARA in liver |
| PMC3011268__F2 | Regulation of Wnt signaling in Xenopus CNC |
| PMC3011892__F1 | Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles. |
| PMC3011892__F4 | Cell cycle pathway containing Treponema denticola differentially regulated genes in calvarial bone compared with sham-infected controls at P ≤ 0.05, adapted from Pathway Express and using the Kyoto Encyclopedia of Genes and Genomes nomenclature |
| PMC3011892__F5 | Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles. |
| PMC3011942__F1 | Phosphatidylinositol 3-kinase-Akt (PI3K-Akt) pathway becomes activated via stimulation of receptor tyrosine kinases (RTKs) and the assembly of receptor-PI3K complexes |
| PMC3012004__F1 | PI3 kinase signaling pathway in glioma |
| PMC3012004__F2 | Sites of action for inhibitors and shRNAs in the EGFR-PI3K-Akt-mTOR pathway |
| PMC3012138__F3 | A network of hits highly enriched in cell cycle-related genes |
| PMC3012148__F2 | Biosynthetic pathway of sphingolipids that mediate expressions of genes associated with cellular processes in cancer |
| PMC3012182__F1 | TRPM channels in insulin secretion |
| PMC3012432__F7 | Diagram illustrating the PS-Tyro3-Akt cell survival signaling pathways |
| PMC3012625__F6 | Numbers of reads in the non-normalized and normalized 454 sequence analysis for genes encoding enzymes in the fatty acid and TAG biosynthetic pathways in bitter melon seeds |
| PMC3013016__F8 | The molecular mechanisms employed by the Ras/MAPK pathway to regulate mTORC1 signaling |
| PMC3013041__F5 | Relationship between transcription factors and their regulatory factors |
| PMC3013516__F8 | The interaction between cPLA2A and TGFBsignaling pathways in hepatic cells |
| PMC3013518__F1 | Vitamin D3 biotransformation pathway |
| PMC3013804__F3 | Case study of the discovered phosphorylation networks associated with insulin signaling pathway |
| PMC3014093__F3 | Upper panel |
| PMC3014256__F3 | A-Kinase Anchoring Proteins: Getting to the heart of the matter |
| PMC3016145__F1 | Intracellular and extracellular chromogranin/secretogranin actions |
| PMC3016890__F1 | The p38MAPKsignalling pathway |
| PMC3016978__F6 | Model for a meiotic gene regulatory cascade initiated by inactivation of a pathway that promotes turnover of meiotic transcripts produced in vegetatively growing cells |
| PMC3017081__F3 | Crosstalk between interleukin signalling pathways |
| PMC3017081__F4 | Cell cycle G1/S check point subnetwork |
| PMC3017463__F4 | Schematic illustartion of microglial (A) and astrocytic (B) events taking place in the spinal cord in neuropathic pain |
| PMC3017908__F6 | Major pathways affected in NMSC |
| PMC3018096__F1 | Adapters in the organization of mast cell signaling |
| PMC3018162__F1 | Schematic and mathematical representations of the main model assumptions |
| PMC3018616__F1 | TGFB superfamily signaling pathway |
| PMC3018769__F8 | Composite figure from all time points of microarray data showing apoptotic pathways in HepG2 cells when exposed to PCB-153 (70µM) and PCB-77 (70µM) |
| PMC3019079__F1 | The homocysteine and folate metabolic pathway |
| PMC3019561__F2 | Mitochondria and the synthesis of phospholipids |
| PMC3019574__F3 | Perspective: Expanding Role of Cyclin Dependent Kinases in Cytokine Inducible Gene Expression |
| PMC3020075__F1 | GPC5 Gene and Its Related Pathways in Lung Cancer |
| PMC3020905__F6 | Molecular Basis for Vulnerability to Mitochondrial and Oxidative Stress in a Neuroendocrine CRI-G1 Cell Line |
| PMC3021097__F2 | Functional significance of itpkc_3 on ITPKC mRNA and Ca2+/NFAT pathway |
| PMC3021128__F7 | Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7 |
| PMC3021368__F2 | PI3K in immune system |
| PMC3021368__F5 | Foxo3 controls DCs functions |
| PMC3021862__F4 | Genes regulated by Survivin in ITD-Flt3+KSL cells and deregulated in LSC are mapped on functional signaling network associated with epidermal growth factor receptor signaling pathway |
| PMC3021995__F3 | Post-transcriptional control of mammalian clock genes |
| PMC3022058__F1 | Outline of UDP-GlcNAc synthetic pathways |
| PMC3022184__F2 | A proposed mechanism of TGFA/EGFR/ras-MAPK activation loop in HNSCC |
| PMC3022188__F1 | Rationale for dual treatment targeting the IGF-1R signaling pathway in RMS |
| PMC3022256__F2 | Patterning the DV axis in Drosophila and Tribolium |
| PMC3022513__F1 | Physiological regulation of the mTOR signaling pathway |
| PMC3022727__F6 | IPA pathway graphical representation of Aryl Hydrocarbon Receptor Signaling |
| PMC3022823__F7 | FBPA clustering on gene expression after direct irradiation |
| PMC3022823__F9 | FBPA clustering on gene expression in the bystander response |
| PMC3023029__F2 | Intracellular transport pathway of Shiga toxin |
| PMC3023131__F7 | Summary of CD83 pathway regulating display of MHC II and CD86 on DCs |
| PMC3023199__F3 | PPARG ligand treatments increase expression of mitochondria-associated metabolic pathways in adipose tissue |
| PMC3023199__F4 | Dysregulated expression of fatty acid and cholesterol synthesis genes in liver is reversed by PPARG ligand treatments |
| PMC3023213__F1 | Multiple substrates of the PI 3-kinase/Akt pathway mediate growth and metabolic signals in skeletal muscle |
| PMC3023296__F3 | Cell cycle, cellular growth and proliferation pathways detected by ingenuity pathways analysis |
| PMC3023470__F9 | Schematic illustration of the sphingolipid metabolic pathway in CHO cells expressing SPHK1/2 and hSPNS2 |
| PMC3023527__F7 | Schematic summary of the results showing the consequences of mPGES-1 mediated PGE2synthesis for LPS-induced neuroinflammation |
| PMC3023586__F1 | Host-cell signalling induced by EPEC Tir |
| PMC3023615__F2 | In fibroblasts, Nod2 senses bacteria at the plasma membrane and recruits the autophagic machinery through direct interaction with ATG16L1 |
| PMC3023986__F2 | Wnt Signaling as a Therapeutic Target for Bone Diseases |
| PMC3024251__F6 | Downregulation of miR-342 is associated with tamoxifen resistant breast tumors. |
| PMC3024260__F1 | Computational and Experimental Study of the Regulatory Mechanisms of the Complement System |
| PMC3024731__F2 | Examples of the signaling role of Cdc42 in selective tissue cell types |
| PMC3024878__F1 | Connectivity map of 42 epidemiological, genetic and clinical variables showing different output such as prevalent AD, prevalent VD, prevalent CIND and control cases |
| PMC3025359__F1 | Mincle- and Dectin-1-mediated signalling in response to mycobacteria |
| PMC3025384__F2 | JAK/STAT3 signaling pathway transmits information from cytokine/chemical signals outside the cell, through the cell membrane, and into the gene promoters on the DNA in the cell nucleus, which causes DNA transcription and activity in the cell |
| PMC3025384__F3 | Wnt signaling plays central role in embryogenesis and human diseases including cancers |
| PMC3025434__F1 | Simplified overview of the pathways involved in miRNA regulation of gene expression in addiction |
| PMC3025468__F11 | Compartmentalization of TNF-R1 signalling and A-SMase activation |
| PMC3025702__F2 | Combination Treatment with Progesterone and Vitamin D Hormone May Be More Effective than Monotherapy for Nervous System Injury and Disease |
| PMC3025761__F1 | Schematic illustration of the various steps involved in the ubiquitin proteasome pathway and general architecture of the cullin 1 (CRL1) and cullin 4 (CRL4)-based E3 ubiquitin ligases |
| PMC3025764__F4 | Metabolic regulation by FOXO1 in skeletal muscle |
| PMC3025834__F1 | Schematic representation of xylose metabolic pathway in metabolically engineered S |
| PMC3026473__F2 | Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets |
| PMC3026729__F7 | Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice |
| PMC3026934__F2 | Signaling pathway induced by Dectin-1 |
| PMC3026990__F5 | Signaling networks associated with PPARD and inflammatory and invasive gene expression |
| PMC3027010__F1 | Schematic review of the molecular mechanisms linking diabetes mellitus and colorectal cancer |
| PMC3027158__F7 | Biological network of genes linked to the canonical pathway "molecular mechanisms of cancer" that were hypomethylated (fold change >1.5) in zebrafish hepatocellular carcinoma compared to healthy liver |
| PMC3027158__F8 | Ingenuity network predicted for genes that were both hypomethylated and increased in expression in zebrafish HCC (shaded red) |
| PMC3027166__F2 | cis-Silencing: The Virus/Transgene and Heterochromatin siRNA Pathways.(A) Virus and sense transgene PTGS: Viruses and transgenes can give rise to primary siRNAs by direct production of dsRNA (during RNA virus replication) or aberrant transcripts |
| PMC3027599__F5 | Ingenuity pathway Analysis network 1 depicting relationships among up-regulated genes in SB300 infection group relative to that of SB1117 infection group at 8 hours |
| PMC3027599__F6 | Ingenuity Pathway Analysis Network 2 depicting relationship among up-regulation Genes in SL1344 vs SB1117 infection groups at 8 hours |
| PMC3028977__F6 | CD36 contributes to inflammation and impaired insulin signalling in adipocytes and macrophages |
| PMC3030591__F4 | Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte |
| PMC3030591__F7 | Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte |
| PMC3030666__F2 | Impact of Aging on Dendritic Cell Functions in humans |
| PMC3030733__F1 | Interventions in nuclear factor erythroid 2-related factor 2-Kelch-like ECH-associated protein 1 signaling pathway |
| PMC3030969__F1 | Tumor suppressor p53 and its signaling pathway |
| PMC3030971__F1 | Key proteins and pathways in the replication stress response network |
| PMC3031055__F3 | TFM-C-induced alteration to IL-12p40 chaperone interactions |
| PMC3031466__F10 | A PtdIns(3)P-mediated signaling pathway that drives the degradation of apoptotic cells |
| PMC3031497__F7 | Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer |
| PMC3031501__F8 | Ablation of Akt2 Induces Autophagy through Cell Cycle Arrest, the Downregulation of p70S6K, and the Deregulation of Mitochondria in MDA-MB231 Cells |
| PMC3031560__F5 | Identification of Novel Molecular Targets for Endometrial Cancer Using a Drill-Down LC-MS/MS Approach with iTRAQ |
| PMC3031870__F1 | MTORC1 and mTORC2 signaling branches |
| PMC3032036__F10 | The paracellular pathway in vertebrates and insects |
| PMC3032315__F3 | Regulation of peripheral tolerance by the intrinsic and extrinsic apoptosis pathways in T and B cells |
| PMC3032410__F7 | Dynamic Distribution of CARD11 at the Immunological Synapse is Regulated by the Inhibitory Kinesin GAKIN |
| PMC3032466__F11 | Expression of cell cycle genes in wild-type (WT) and CKX-4 tubers after GA3-mediated tuber sprouting |
| PMC3032466__F13 | Expression of auxin transport and signaling genes in wild-type (WT) and CKX-4 tubers after GA3-mediated tuber sprouting |
| PMC3032584__F1 | NF-kappaB, a mediator for lung carcinogenesis and a target for lung cancer prevention and therapy |
| PMC3032697__F15 | Time course changes in cytokine network pathways of lungs from 9 V/null mice |
| PMC3033145__F2 | Anticoagulant properties of endothelial cells |
| PMC3033158__F3 | Signal pathways in systemic regulation of hepcidin |
| PMC3033173__F2 | LMP1 in promoting survival in PTLD |
| PMC3033586__F2 | Wnt pathway and its regulation of Beta-catenin in stem cells and cancer |
| PMC3033586__F3 | Hypothetical scheme for bacteria-regulated intestinal stem cells and tumorigenesis |
| PMC3033602__F1 | Adapted from KEGG colorectal cancer pathway [, , ] |
| PMC3034442__F3 | Glycine synthesis and degradation |
| PMC3034644__F2 | Self-regulation in Xenopus dorsal-ventral patterning.The pathway consists of a network of BMP-interacting proteins |
| PMC3034925__F1 | Simplified schematic representation of the link between LPS-induced microglial activation, inflammatory mediators, and dopaminergic neurodegeneration |
| PMC3035032__F3 | Simplified schematic illustrating molecular mechanisms of neurite regulation |
| PMC3035094__F6 | Cic regulatory elements mediate Torso and EGFR responses |
| PMC3035137__F2 | Effects of Hfe deficiency and the associated low hepcidin and intracellular iron levels on macrophage TLR4 signaling |
| PMC3035360__F1 | Synthetic view of the p53 pathway |
| PMC3035565__F11 | WNKs: atypical protein kinases with pleiotropic actions |
| PMC3035594__F3 | Integrated view of Wnt pathway |
| PMC3035636__F1 | Targeting Metabolic Remodeling in Glioblastoma Multiforme |
| PMC3035650__F7 | Local Proinflammatory Signalling Loop Facilitates Adverse Age-Associated Arterial Remodeling |
| PMC3035679__F3 | Human inherited and mouse experimental defects in the cholesterol biosynthesis pathway that cause myelin disorders |
| PMC3035679__F4 | Human inherited and mouse experimental defects in the glycosphingolipids synthesis pathway that cause myelin disorders |
| PMC3035754__F1 | Regulatory network governing mitochondrial functions orchestrated by PGC-1A |
| PMC3035824__F5 | Mapk signaling pathway from KEGG |
| PMC3035871__F2 | Targeting Fas in osteoresorptive disorders |
| PMC3035969__F5 | Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression |
| PMC3035979__F2 | Gene expression profile |
| PMC3035994__F1 | Simplified model of nutrient signaling pathways influencing metabolic responses |
| PMC3036164__F8 | Alcama mediates Edn1 signaling during zebrafish cartilage morphogenesis |
| PMC3036178__F1 | Lymphotoxin and the immediate tumor necrosis factor (TNF) family |
| PMC3037521__F2 | Selective elimination of messenger RNA underlies the mitosis-meiosis switch in fission yeast |
| PMC3037729__F1 | Interaction between PI3K/Akt and Wnt signaling pathways mediates diverse cellular effects through downstream messengers |
| PMC3037747__F2 | Cyclin D1, at the center of MCL pathogenesis |
| PMC3037747__F4 | BCR, NFKB, and PI3K/AKT/mTOR deregulation in MCL |
| PMC3037835__F5 | Major pathways of lipid metabolism in yeast |
| PMC3038050__F1 | Mechanisms by which CD44 can modulate cell death |
| PMC3038181__F1 | Activation of the PI3K/Akt pathway in cancer |
| PMC3038194__F1 | Therapeutic strategies and mechanisms of tumorigenesis of HER2-overexpressing breast cancer |
| PMC3038250__F4 | PI3K/Akt and RAS/BRaf/MEK pathways are frequently altered in melanoma |
| PMC3039688__F7 | Mapping Protein Interactions between Dengue Virus and Its Human and Insect Hosts |
| PMC3039708__F2 | T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics |
| PMC3039708__F3 | T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics |
| PMC3039745__F1 | TRAF6 and A20 control K63-linked ubiquitination of Beclin 1 to trigger autophagy |
| PMC3039924__F1 | Insulin-like growth factor receptor 1 (IGF1R) signaling pathway and potential mechanisms of resistance to IGF1R blockade (red asterisks) |
| PMC3039927__F1 | Organellar Ca2+ buffering and intracellular Ca2+ dynamics |
| PMC3039931__F2 | Tyrosine kinase pathways leading to CARD9 and TLR signaling responses |
| PMC3039931__F3 | Inhibitory pathways in innate cells utilizing ITIM or "inhibitory" ITAM signaling pathways |
| PMC3040416__F3 | Proteins oxidized by extracellular EhCySS control cell signaling and morphology |
| PMC3040753__F3 | Gene Expression Profiling of Vasoregression in the Retina–Involvement of Microglial Cells |
| PMC3040966__F4 | Working model for the role of WRN in the signaling pathways involved in pancreatic cancer cells |
| PMC3041769__F4 | Antibodies against CD20 or B-Cell Receptor Induce Similar Transcription Patterns in Human Lymphoma Cell Lines |
| PMC3041778__F8 | Proposed mechanism by which PRL may affect CPT1 enzyme activity in breast cancer cells |
| PMC3042129__F8 | Unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening |
| PMC3042531__F3 | Regulation of Innate Immunity by signaling pathways emerging from the endoplasmic reticulum. |
| PMC3042643__F1 | EGFR signaling pathway |
| PMC3042730__F2 | Inflammatory signals regulate hematopoietic stem cells |
| PMC3043094__F2 | Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach |
| PMC3043094__F3 | Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach |
| PMC3043094__F4 | Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach |
| PMC3043245__F3 | Signalling between p53 and the IGF-AKT-mTORC1 pathway |
| PMC3043627__F1 | Simplified model for the intersection of signaling pathways regulating protein synthesis and degradation |
| PMC3044050__F6 | Spry2 and Spry2Y55F function in the context of EC MAPK signaling |
| PMC3044403__F1 | The GlcNAc and GalNAc salvage and O-GlcNAc signaling pathways |
| PMC3044438__F3 | Identifying genomic and developmental causes of adverse drug reactions in children |
| PMC3044944__F6 | Hypothetic model for TGF-Beta-regulated KLF4 proteolysis |
| PMC3045367__F1 | Exploring the Evolutionary Relationship of Insulin Receptor Substrate Family Using Computational Biology |
| PMC3045450__F4 | NAViGaTing the Micronome - Using Multiple MicroRNA Prediction Databases to Identify Signalling Pathway-Associated MicroRNAs |
| PMC3045483__F1 | Interactions occuring in the ovarian mural granulosa cells (GC) and cumulus cells (CC) after the administration of hCG for ovulation induction |
| PMC3045531__F9 | Snail repressor is required for PMC ingression in the sea urchin embryo |
| PMC3045562__F1 | Neural pathway for habituation in response to odors |
| PMC3045854__F1 | Memory genes identified in model systems overlap with genes identified in human mental retardation |
| PMC3046044__F1 | Molecular mechanisms involved in nasopharyngeal carcinoma (NPC) development |
| PMC3046063__F7 | Proposed working model and protein-protein interaction map |
| PMC3046427__F2 | Beta-Catenin is at the hub of multiple signaling pathways |
| PMC3046452__F7 | Melatonin regulation of breast cancer cell invasion |
| PMC3046639__F1 | RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it |
| PMC3046768__F2 | Schematic of the base excision repair pathways present in mitochondria |
| PMC3046919__F7 | Proposed model of the process of A20 |
| PMC3047044__F1 | Simplified schematic version of the epidermal growth factor receptor (EGFR) signaling cascade |
| PMC3047086__F9 | Suggested modes of the involvement of Nrf2/ARE in the regulation of AML cell differentiation |
| PMC3047474__F1 | Architecture of intestinal TD and TI IgA responses |
| PMC3047474__F2 | Innate IgA-inducing signaling pathways |
| PMC3047603__F3 | CYP17 inhibitors for prostate cancer therapy |
| PMC3047613__F2 | Model: The kinase IKK may activate Htt degradation by a mammalian version of the yeast Cvt pathway |
| PMC3047627__F3 | RECK pathway in stromal-epithelial interaction in prostate cancer |
| PMC3047755__F7 | Proposed model for how Shh signaling pathway negatively regulates its mitogenic potential through Beta-arrestin 1 |
| PMC3047785__F5 | CD28 signaling events |
| PMC3047798__F1 | Ubiquitin-mediated regulation of the core Wnt pathway components APC, Axin and Beta-catenin |
| PMC3048376__F2 | Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli |
| PMC3048376__F5 | Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli |
| PMC3048376__F9 | Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli |
| PMC3048459__F3 | TGFB Smad-dependent signaling pathway: TGFB exerts its effect by binding and activating type II receptor (TGFBR2) and then type I receptor (TGFBR1) |
| PMC3048558__F7 | Proposed mechanism of gene regulation in response to extracellular and intracellular dsRNA stimulation |
| PMC3048826__F12 | Signaling pathway of HMGB1-mediated ischemia reperfusion injury |
| PMC3048826__F8 | Hsp72 regulates oxidative stress-induced HMGB1 cytoplasmic translocation and release |
| PMC3048839__F10 | Schematic representation of IH-induced increase in adrenal medullary NPY by activation of reactive oxygen species (ROS) signaling pathway |
| PMC3048914__F6 | Differentially expressed genes in the MICs as compared to NSPCs |
| PMC3049118__F3 | Endocrine system development and function genes increase in the spleen of CVB3 infected males at 12 h pi |
| PMC3049118__F6 | Cardiovascular disease genes increase in the spleen of CVB3 infected males at 12 h pi |
| PMC3049195__F1 | Proposed diphthamide biosynthesis pathway |
| PMC3049335__F1 | The Nrf2 pathway in PD pathogenesis |
| PMC3049553__F1 | MAPK pathway activation in melanoma |
| PMC3049838__F3 | Wnt signaling pathway activation in R1A deficient tumor cells |
| PMC3049852__F1 | Multifunctional effects of CMKLR1 activation |
| PMC3049961__F8 | Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ÃŽâ€EGFR |
| PMC3050040__F1 | Major kinase signaling cascades involved in drug addiction |
| PMC3050610__F2 | HIF activation in cancer |
| PMC3050667__F7 | Model of a Slit/miR-218/Robo axis that regulates Vegf signaling and endocardial migration |
| PMC3050844__F5 | Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection - A Meta-Analysis of Genomic Signatures in Circulating Leukocytes |
| PMC3050939__F3 | Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis |
| PMC3051001__F1 | RIP1 COMES BACK TO LIFE AS A CELL DEATH REGULATOR IN TNFR1 SIGALING |
| PMC3051174__F3 | TLR4 signaling - a converged immune response pathway for hemorrhagic shock and septic shock |
| PMC3051261__F11 | Schematic Models of Tap46/Tap42/A4 Functions in TOR Signaling Pathways in Eukaryotes.(A) TOR signaling in yeast |
| PMC3051378__F5 | Resulting endoplasmic reticulum (ER) stress and unfolded protein response (UPR) gene network from a modelling approach using the set of differentially regulated genes common to all pancreatic cancer cell lines after nemorosone treatment |
| PMC3053348__F7 | The Danger Signal S100B Integrates Pathogen- and Danger-Sensing Pathways to Restrain Inflammation |
| PMC3053440__F1 | Toll-like receptor signaling pathway |
| PMC3055312__F1 | Signaling pathways regulating GSK3 and functions of GSK3 related to mood regulation |
| PMC3055447__F4 | A schematic diagram of pyramidal cells (triangular) and GABAergic interneurons (square) within the trisynaptic pathway of the hippocampus |
| PMC3055758__F8 | Mechanism of cAMP inhibition of MAPK activity |
| PMC3055988__F2 | Further implications of G-/GM-CSF-induced JAK-STAT signaling in peripheral sensory neurons |
| PMC305600__F7 | An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity |
| PMC3056121__F1 | Regulatory natural autoantibodies to apoptotic cells: Pallbearers and protectors |
| PMC3056141__F1 | DNA-mediated activation of innate immune signaling |
| PMC3056511__F7 | Schematic summarizing the present findings |
| PMC3056800__F7 | Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds |
| PMC3057147__F1 | Top associated network functions for miR-141 and miR-200c |
| PMC3057165__F1 | Pathways by which toll-like-receptor signals and ligation of FcG receptor lead to the production of interleukin |
| PMC3057180__F1 | Backup DNA repair pathway |
| PMC3057180__F2 | Exploiting synthetic lethal interactions for the treatment of human cancer |
| PMC3057454__F2 | Autophagy in Immunity and Cell-Autonomous Defense Against Intracellular Microbes |
| PMC3057561__F1 | Human Th17 differentiation: IL-1 signaling appears to cooperate with a pathway driven by TGF-B+ IL-6/IL-21/IL-23 to induce human Th17 cells, associated with expression of ROR-c and Stat3 |
| PMC3057579__F9 | Hypothetical diaphragm of HS7 induced apoptosis and inhibition of Wnt/Beta-catenin signaling pathway in HT-29 colon cancer cells |
| PMC3057653__F1 | Schematic diagram illustrating an overview of cellular injury and inflammatory-mediated steps in development of leiomyoma as compared with uterine scar formation caused by mechanical injury (i.e., myomectomy and cesarean delivery) |
| PMC3057977__F3 | Comparison of Expression Profiles in Ovarian Epithelium In Vivo and Ovarian Cancer Identifies Novel Candidate Genes Involved in Disease Pathogenesis |
| PMC3058199__F6 | Noonan syndrome and clinically related disorders |
| PMC3058235__F1 | Control of GnRH secretion by growth factors and small molecules produced by glial cells |
| PMC3058357__F3 | GRAIL and Otub1 regulation by the mTOR pathway controls naïve CD4 T cell proliferation |
| PMC3058380__F5 | Focal adhesions in osteoneogenesis |
| PMC3058407__F1 | Antiviral apoptotic pathway is mediated by IRF-3 and Bax |
| PMC3058926__F4 | Proof of Concept: A review on how network and systems biology approaches aid in the discovery of potent anticancer drug combinations |
| PMC3058926__F5a | Proof of Concept: A review on how network and systems biology approaches aid in the discovery of potent anticancer drug combinations |
| PMC3058986__F8 | Possible role of RACK1 in VEGF/Flt1-induced cell migration |
| PMC3059306__F1 | TSC mediated signaling in the central nervous system |
| PMC3059437__F1 | Shmt1 Heterozygosity Impairs Folate-Dependent Thymidylate Synthesis Capacity and Modifies Risk of Apcmin-Mediated Intestinal Cancer Risk |
| PMC3059560__F1 | Targeting the embryonic gene Cripto-1 in cancer and beyond |
| PMC3059752__F3 | Knowledge-based pathway analysis (Genomatix BiblioSphere Software) indicating the network of high BMI-associated genes |
| PMC3059896__F2 | Genetics and molecular pathology of Stargardt-like macular degeneration |
| PMC3060045__F2 | ErbB receptor signaling and regulation |
| PMC3060239__F5 | Model of the RBP-ROH/STRA6/JAK/STAT pathway |
| PMC3060320__F2 | Schematic illustration of signalling within the type I interferon (IFN) system |
| PMC3060380__F1 | Myostatin activity and muscle growth |
| PMC3060494__F6 | RPA/9-1-1- and hMSH2-mediated ATR activation in DNA damage signaling |
| PMC3060774__F3 | Chromatin remodelling during development |
| PMC3060778__F4 | Comparative and demographic analysis of orangutan genomes |
| PMC3060875__F3 | Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses |
| PMC3060875__F5 | Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses |
| PMC3060878__F5 | FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways |
| PMC3060910__F1 | Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells |
| PMC3061041__F1 | Negative regulation of the IMD pathway |
| PMC3061066__F7 | Model demonstrating the possible mode of action of hSSB1 |
| PMC3061251__F1 | Viral infection triggers the IFNB signal transduction pathway of the host innate immune system, activating the antiviral state |
| PMC3061277__F1 | Simple schema of the IGF pathway and approaches to its inhibition |
| PMC3061395__F10 | The bifurcating parallel signal transduction pathways downstream of the IL-13R that regulate 15-LO gene expression in primary human monocytes |
| PMC3061571__F2 | Two different ubiquitin ligases control the stability of the Aurora-A and Polo-like kinases |
| PMC3061884__F7 | 100 frequent associations obtained after p value cut off in BLCA with CDCOCA |
| PMC3061884__F9 | 100 frequent associations obtained after p value cut off in MCL with CDCOCA |
| PMC3061960__F5 | NFKB activation in B cells |
| PMC3062054__F2 | Roles for Growth Factors in Cancer Progression |
| PMC3062054__F4 | Roles for Growth Factors in Cancer Progression |
| PMC3062410__F2 | Networks most highly represented by transcripts differentially associated with HuR after IR treatment |
| PMC3062538__F5 | The regulation of IgA class switching. |
| PMC3062540__F7 | IL1B Induced Smad 7 Negatively Regulates Gastrin Expression. |
| PMC3062664__F1 | Metabolic insulin signaling pathway genes genotyped in the discovery cohort |
| PMC3062764__F2 | Dynamics of mitochondrial quality control |
| PMC3063194__F1 | Elicitation of innate immune response in EBV infection |
| PMC3063194__F2 | Evasion of immune responses by individual EBV products |
| PMC3063577__F2 | Simplified diagram showing some of the identified BCR pathway members |
| PMC3063605__F1 | Simplified cartoon of PRR signaling in epithelial cells showing only the canonical pathway of NFKB activation and some of the key receptors, adaptors, and kinases involved |
| PMC3064126__F6 | PHEX, DMP1, matrix extracellular phosphoglycoprotein (MEPE), and ASARM peptides are proposed to dynamically regulate FGF23 expression in bone |
| PMC3064222__F9 | Proposed signal transduction pathways in NG following receptor activation with leptin and CCK-8 |
| PMC3064322__F5 | Model showing the regulation of PPARA by metabolism and PAR bZip transcription factors |
| PMC3064425__F2 | Dietary agents on the extrinsic and intrinsic pathways of apoptosis in prostate cancer |
| PMC3064559__F3 | Interconnectivity of signaling pathways emanating from TLRs and TACI |
| PMC3064560__F3 | Analogue 3 also showed potent antiproliferative activity against the highly invasive non-small-cell lung cancer cell line CL1-5 with an ED50 value of 0.11 µM |
| PMC3064843__F5 | DNA Repair Deficiency and Neurological Disease |
| PMC3064890__F4 | BRCA2/RAD51 pathway in response to DSBs |
| PMC3064890__F5 | BRCA2/RAD51 pathway in the response to stalled forks |
| PMC3064905__F3a | Genomic revelations of a mutualism: the pea aphid and its obligate bacterial symbiont |
| PMC3065201__F1 | Schematic diagram illustrating an overview of cellular injury and inflammatory-mediated steps in development of leiomyoma as compared with uterine scar formation caused by mechanical injury (i.e., myomectomy and cesarean delivery) |
| PMC3065454__F8 | Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer |
| PMC3065471__F3 | Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map |
| PMC3065553__F5 | Metabolic pathway for pitavastatin |
| PMC3065765__F3 | Iron in regulating the mTOR signaling pathway |
| PMC3065826__F1 | Metabolism, Cell Surface Organization, and Disease. |
| PMC3066048__F1 | Complementation of Saccharomyces cerevisiae coq7 Mutants by Mitochondrial Targeting of the Escherichia coli UbiF Polypeptide |
| PMC3066060__F2 | Simplified schematic representation of the apoptosis pathway in mammals and Drosophila |
| PMC3066660__F6 | Significantly expressed genes in cytokine-cytokine receptor interaction pathway disturbed by SM at different time points |
| PMC3067333__F5 | Schematic presentation of Nag PTS and parts of the central metabolism of R |
| PMC3067813__F7 | Model of proposed HEB, GATA3, and Notch1 interactions |
| PMC3068086__F4 | Coordinately up-regulated TCA cycle genes in CD8+ T cells from the VIR group (VIR versus LTNP) illustrated in TCA cycle pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) |
| PMC3068086__F5 | Coordinately up-regulated cell cycle genes in CD8+ T cells from the VIR group (VIR versus BDL) illustrated in cell cycle pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) |
| PMC3068086__F6 | Branches of MAPK pathway significantly enriched in CD4+ T cells from the LTNP group (BDL versus LTNP) |
| PMC3068086__F7 | Schematic overview of the network of enriched pathways related to HIV disease progression |
| PMC3068163__F1 | Melanoma Molecular Disease Model |
| PMC3068308__F5 | TGFB signaling pathway |
| PMC3068560__F4 | Proteome of sickle cell disease: insights from exploratory proteomic profiling |
| PMC3068924__F4 | CAERUS: Predicting CAncER oUtcomeS Using Relationship between Protein Structural Information, Protein Networks, Gene Expression Data, and Mutation Data |
| PMC3069071__F7 | Hedgehog Inhibition Promotes a Switch from Type II to Type I Cell Death Receptor Signaling in Cancer Cells |
| PMC3069496__F1 | miRNA biogenesis pathway |
| PMC3069685__F2 | An Activating Transcription Factor 5-Mediated Survival Pathway as a Target for Cancer Therapy |
| PMC3069698__F1 | The Fanconi Anemia and Breast Cancer Susceptibility Pathways |
| PMC3069769__F1 | Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy |
| PMC3069839__F5 | Regulation of Atm pathway genes after Rif-Phen-MCT |
| PMC3069928__F1 | Biological actions of IGF-1 are mediated by IGF-1R and modulated by IGFBPs |
| PMC3069932__F9 | Proposed role of Nodal in human placental development and mechanism of Nodal-regulated trophoblast invasion |
| PMC3070284__F2 | Endothelial growth factor receptor (EGFR) signaling pathway |
| PMC3070484__F1 | iNKT cell autoreactivity: what is "self" and how is it recognized? |
| PMC3070553__F11 | Signaling modules identified by correlational analysis of end points |
| PMC3070611__F3 | One experimental result of identified pathways from ovarian expression data |
| PMC3070611__F4 | One of experimental result from pathways intersection |
| PMC3070611__F5 | The shortest pathway identified by our system |
| PMC3070659__F1 | Representative axon regeneration-regulating pathways discovered in genetic model organisms |
| PMC3070842__F1 | Lessons on transcriptional control from the serum response network |
| PMC3070844__F3 | Top-scoring network created by Ingenuity Pathway Analysis |
| PMC3070849__F1 | Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation |
| PMC3070859__F1 | Cohesin regulates expression of genes that control differentiation, morphogenesis, proliferation, and pluripotency |
| PMC3071786__F6 | Changes in mRNA levels among various signalling pathway members following inhibition of FGFR activity |
| PMC3071831__F7 | Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures |
| PMC3071916__F2 | Insights into the Pathogenesis and Treatment of Cancer from Inborn Errors of Metabolism. |
| PMC3071979__F2 | Inhibition of NFKB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice |
| PMC3072047__F1 | Carbon flux rerouting during Mycobacterium tuberculosis growth arrest |
| PMC3072066__F5 | Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state |
| PMC3072659__F1 | Pathways that modulate canonical Wnt signaling |
| PMC3073074__F1 | The pathway of propionyl-CoA to succinyl-CoA metabolism is displayed |
| PMC3073290__F1 | Models of how IFNB and GA activate PI3KD/Akt and MEK/ERK pathways to induce sIL-1Ra production in monocytes |
| PMC3073335__F2 | RNA helicases of the RIG-I-like receptor (RLR) family play a crucial role in the innate antiviral response |
| PMC3073487__F4 | Functions of 14-3-3 in tumor-suppressor pathways |
| PMC3073545__F2 | Endocannabinoids in Liver Disease |
| PMC3073571__F8 | Cone-specific Visual Cycle |
| PMC3073693__F4 | Molecular pathways in dystonia |
| PMC3073741__F1 | Complement and Viral Pathogenesis |
| PMC3073781__F6 | Schematic overview of the MDM2 and p53 signalling pathway |
| PMC3073847__F1 | TGFB signaling pathway TGFB is secreted in a latent form and activation is mediated by several molecules including furin and emilin |
| PMC3073855__F1 | Childhood Obesity - 2010: Progress and Challenges |
| PMC3074487__F8 | Migration of FGF7-stimulated epithelial cells and VEGF-A-stimulated HUVECs depends on EGFR transactivation by ADAM17 |
| PMC3074954__F1 | ROS have different origins |
| PMC3075071__F1 | Parsing out the complexity of RAF inhibitor resistance |
| PMC3075080__F3 | Proposed ACE2/ANG-(1-7)/Mas signaling pathways in the central nervous system |
| PMC3075242__F6 | Differential Expression of MicroRNAs in Tumors from Chronically Inflamed or Genetic (APCMin/+) Models of Colon Cancer. |
| PMC3075259__F4 | Data Integration Workflow for Search of Disease Driving Genes and Genetic Variants |
| PMC3075376__F1 | Targeting GSK-3 family members in the heart: A very sharp double-edged sword |
| PMC3075510__F9 | Phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3 (GSK3) signalling is required for expression of a subset of interleukin-10 (IL-10) inducible genes |
| PMC3075579__F4 | The PI3K pathway in TLR-signaling |
| PMC307558__F1 | TGFB signaling pathway |
| PMC3075605__F2 | NFKB signaling pathways downstream of TNFR1, TLR4 and TCR/CD28 |
| PMC3075645__F8 | DNA damage-triggered activation of SAPK/JNK at late times following cisplatin treatment |
| PMC3075710__F3 | Regulated fatty acid synthesis and metabolism during cell differentiation |
| PMC3076058__F2 | Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction |
| PMC3076281__F2 | Sphingolipid effects on intrinsic and extrinsic apoptotic pathways |
| PMC3076281__F3 | Effect of sphingolipids on the PI3K/AKT pathway |
| PMC307637__F5 | Model for the mobilization of Ty1 elements through a branch of the DNA-damage checkpoint pathway triggered by telomere erosion |
| PMC3076503__F4 | Bioenergenesis neurotransmitter pathways with differentially expressed genes between frontal cortex and hippocampus |
| PMC3076503__F5 | Bioenergenesis neurotransmitter pathways with differentially expressed genes between frontal cortex and hypothalamus |
| PMC3076854__F2 | Global transcriptome analysis reveals CB1R-dependent, PHX-induced up-regulation of key cell-cycle proteins |
| PMC3076924__F2 | Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders |
| PMC3076924__F4 | Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders |
| PMC3077082__F1 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F2 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F3 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F4 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F6 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077214__F1 | Signaling pathway components used to test gene-compound interactions |
| PMC3077378__F7 | Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling |
| PMC3077393__F8 | GATA2 Mediates Thyrotropin-Releasing Hormone-Induced Transcriptional Activation of the Thyrotropin B Gene |
| PMC3077544__F2 | Akt regulates numerous biological functions by phosphorylating distinct protein substrates |
| PMC3077564__F3 | Activation of glia and neurons in the dorsal horn of the spinal cord after peripheral injury |
| PMC3077584__F6 | The effects of apoA-I on TNFA mRNA stabilization in LPS-stimulated macrophages |
| PMC3077649__F7 | Model of Egr-1/GGPPS/Erk1/2 pathway regulating insulin resistance in hyperinsulinism |
| PMC3077819__F2 | Widespread extracellular matrix (ECM) pathway silencing by DNA hypermethylation in colon cancer |
| PMC3077922__F3 | Gene expression changes in response to zebularine therapy in vivo |
| PMC3078022__F1 | Tumor heterogeneity and strategies to overcome kinase inhibitor resistance in cancer: Lessons from melanoma |
| PMC3078187__F1 | Signaling Cell Death from the Endoplasmic Reticulum Stress Response |
| PMC3078450__F5 | Network annotation of genes differentially expressed according to the CD133 status in HT-29 using ingenuity pathway analyses |
| PMC3078497__F1 | Effector signaling pathways activated during ischemia preconditioning |
| PMC3078503__F4 | PIKKs and TCR-associated pathways |
| PMC3078523__F2 | Heme Oxygenase-1, a Critical Arbitrator of Cell Death Pathways in Lung Injury and Disease |
| PMC3078731__F3 | Central prostate cancer-related processes and their miRNA-mediated regulation |
| PMC3079059__F1 | Control of intracellular heme levels: Heme transporters and Heme oxygenases |
| PMC3079374__F1 | Simplified schematics of the MAPK and PI3K pathways in melanoma and the clinical compounds available for their inhibition |
| PMC3079783__F1 | Leptin Signaling in Intestinal Epithelium Mediates Resistance to Enteric Infection by Entamoeba histolytica |
| PMC3079800__F1 | Parenteral Nutrition Impairs Lymphotoxin B Receptor Signaling via NF- KB |
| PMC3080176__F2 | Diagrammatic representation of the top three canonical signaling pathways, proposed by the Ingenuity Pathways Analysis program, associated with differentially expressed genes in the microarray dataset |
| PMC3080795__F2 | Scheme for CCM including main pathways - glycolysis/gluconeogenesis, penthaphosphate pathway, citrate cycle, overflow pathway |
| PMC3080846__F1 | Innate Immune Sensing of DNA |
| PMC3080858__F6 | PDP-1 Links the TGFB and IIS Pathways to Regulate Longevity, Development, and Metabolism |
| PMC3080979__F2 | Partial hepatectomy stimulates anandamide production through a pathway involving conjugation of arachidonic acid and ethanolamine by FAAH |
| PMC3081173__F4 | Cell adhesion molecules nectins and associating proteins: Implications for physiology and pathology |
| PMC3081180__F7 | The participation of MCP-1, TNFA, MMP-9, E-cadherin, and Beta-catenin in macrophage fusion |
| PMC3081368__F8 | HMGB factors are required for posterior digit development through integrating signaling pathway activities |
| PMC3081520__F2 | Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease |
| PMC3081520__F4 | Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease |
| PMC3081620__F1 | Representative cascade of the TGFB pathway |
| PMC3081824__F3 | Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing |
| PMC3081824__F5 | Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing |
| PMC3081924__F10 | Model for SENP2-mediated modulation of Mdm2 in regulating p53 |
| PMC3082271__F5 | NVN for Putative CHS-Mediated (CHS4) Medicarpin Biosynthesis.Nodes in the network resemble individual genes, and the connecting edges represent coexpressed links |
| PMC3082499__F2 | Mediators of the extrinsic pathway of PCD by Fas and TNFR-1 signaling |
| PMC3082499__F5 | Anti-apoptotic mechanisms of Akt |
| PMC3082570__F1 | Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line |
| PMC3082642__F3 | HBOT affects gene expression in the Nrf2 Pathway |
| PMC3082833__F1 | During innate immune activation via LPS-LPB-TLR4, a number of factors of the coagulation pathway are activated, creating the cooperative immuno-coagulative response |
| PMC3083340__F3 | Top network affected by MAA |
| PMC3083885__F1 | Insulin signaling pathway showing binding of insulin with the insulin receptor leading to the activation of glucose transporter 4 which imports glucose into the cell |
| PMC3083931__F1 | Canonical and noncanonical nuclear factorKB (NFKB) activation pathways |
| PMC3083942__F3 | Proposed model for Syk in mediating oxidative stress-induced calcium release |
| PMC3083963__F1 | Brain-derived neurotrophic factor (BDNF) gene and stimulated intracellular signaling cascades after activation of tropomyosin-related kinase (Trk)B |
| PMC3083967__F5 | Key regulators of the mammalian target of rapamycin signaling pathway |
| PMC3084000__AF1 | Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003). |
| PMC3084021__F1 | Conservation of the RB and Hippo signaling pathways in humans and fruit flies |
| PMC3084093__F4 | Proteins encoding the CAF and tumor stroma-associated genes from seven different epithelial tumors share common involvement in the MAPK signaling pathway and focal adhesion |
| PMC3084294__F4 | The Complete Genome Sequence of 'Candidatus Liberibacter solanacearum', the Bacterium Associated with Potato Zebra Chip Disease |
| PMC3084393__F10 | Proposed diagram for Alpha-mangostin-induced apoptosis in COLO 205 cells |
| PMC3084715__F1 | Exploring Metabolic Pathway Reconstruction and Genome-Wide Expression Profiling in Lactobacillus reuteri to Define Functional Probiotic Features |
| PMC3084988__F2 | TLR structure and signaling |
| PMC3085438__F5 | Working model for the role of CCN6 in breast cancer invasion |
| PMC3085544__F1 | Intracellular signaling by the leptin (LepRb - cyan) and insulin receptor (magenta) |
| PMC3085710__F4 | KEGG Pathway Map () |
| PMC3085878__F3 | TLR-induced microbial resistance |
| PMC3086058__F1 | Representation of genes of the vascular endothelial growth factor (VEGF) signaling pathway and the sites at which bevacizumab, sorafenib, sunitinib, brivanib, and cilengitide are known to act |
| PMC3086210__F9 | NH2-terminal Propeptide of Type I Procollagen Acts Intracellularly to Modulate Cell Function |
| PMC3086918__F1 | Mind the dbGAP: The Application of Data Mining to Identify Biological Mechanisms |
| PMC3087179__F5 | IL-4R Drives Dedifferentiation, Mitogenesis and Metastasis in Rhabdomyosarcoma |
| PMC3087601__F1 | Cellular and bacterial profiles associated with oral epithelium-microbiota interactions |
| PMC3087811__F8 | Schematic model for the role of TGFB signaling pathways in iTreg and Th17 cell development |
| PMC3087899__F6 | NFKB pathway activation via death receptor signaling |
| PMC3087924__F1 | Autophagy in macrophages |
| PMC308804__F4 | Visualizing protein interaction networks in HPRD |
| PMC3088084__F4 | Therapeutic effects can be monitored using DMR on scant cell populations |
| PMC3088358__F7 | The extracellular network of proteins that control D-V patterning |
| PMC3088722__F6 | Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells |
| PMC3088996__F3 | Regulatory role of ATM in cellular responses to DNA DSB repair |
| PMC3089033__F8 | Diagram of the proposed cell survival signaling pathway in ER+ breast cancer cells with PI3KCA mutations and low phosphorylated Akt |
| PMC3089562__F7 | Proposed model of how endocardial Jarid2 expression regulates myocardial development |
| PMC3089575__F8 | Proposed interconnection between PE synthesis and conversion (PL interconversion triad) during LD biosynthesis |
| PMC3089810__F2 | Receptors, subcellular compartments and the regulation of peripheral B cell responses: the illuminating state of anergy |
| PMC3089878__F2 | Cholesterol transport in the CNS |
| PMC3089989__F2 | Gene expression pattern of the P38 MAPK signaling pathway |
| PMC309045__F1 | CRP-dependent (A) and CcpA-dependent (B) carbon catabolite repression pathways and the Ntr regulatory pathway (C) |
| PMC3090458__F3 | BAFF and APRIL signaling pathways in B cells |
| PMC3091055__F4 | PepMV infection of tomato affects the citrate cycle and PTGS |
| PMC3091116__F5 | Protein factors and signaling pathways involved in photosynthetic redox control of plastid transcription |
| PMC3091413__F4 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways based on the Caucasian population |
| PMC3091413__F5 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways based on the Asian population |
| PMC3091413__F6 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways |
| PMC3091413__F7 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways |
| PMC3091517__F2 | Ras/PI3K/PTEN/Akt/mTOR Pathway and Potential Sites of Therapeutic Intervention |
| PMC3091517__F3 | Interactions between the Ras/Raf/MEK/ERK, Ras/PI3K/PTEN/mTOR and Wnt/Beta-Catenin Pathways that Result in the Regulation of Protein Translation and Gene Transcription |
| PMC3091524__F3 | Role of ATR- or ATM-dependent modulation of WRN function in promoting correct recovery from replication arrest |
| PMC3091595__F2 | Bcl-2 as an attractive target for modulating different modes of cell death in cancer therapy due to close communications with mediators of apoptosis, programmed necrosis, and autophagy |
| PMC3091668__F4 | Putative TLR signal pathway |
| PMC3091668__F5 | Putative TCR signal pathway |
| PMC3091670__F2 | Interferon signalling cascade |
| PMC3091670__F3 | Complement pathway |
| PMC3091682__F2 | Correlation of Predicted miRNA Targets with Hosts |
| PMC3091694__F6 | Toll-like Receptor signalling canonical pathway |
| PMC3091695__F3 | Stress-induced pathways in the PVN of the hypothalamus of DBA/2J (A) and C57BL/6 (B) mice |
| PMC3091753__F3 | Representative genes that responded to [BF/S+L/Ep] treatment |
| PMC3091762__F9 | IPA representation of the complement system pathway enriched in cluster 6, 3 hours post-infestation with P |
| PMC3091804__F1 | Schematic overview of potential links between calcium, hormonal and developmental signals and cell cycle regulators; note that the proposed scheme is not complete |
| PMC3092098__F1 | The genes and pathways associated with Crohn's disease pathogenesis |
| PMC3092273__F1 | Complementary signaling pathways activated in human cancer cells |
| PMC3092277__F1 | Hippo signaling network in mammals |
| PMC3092286__F1 | Nonlinear signaling through the PI3K-Akt pathway |
| PMC3092522__F1 | HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies |
| PMC3092604__F1 | General scheme of the SBP in Tritryps |
| PMC3092604__F2 | Lipid remodeling pathways in mammals, yeast and T |
| PMC3092676__F4 | Emerging molecular functions of RASSF8 |
| PMC3092918__F1 | Metabolic network used for metabolic flux analysis |
| PMC3093193__F2 | Update on the regulation of mammalian melanocyte function and skin pigmentation |
| PMC3093412__F1 | Viperin Links Lipid Bodies To Immune Defense |
| PMC3093880__F8 | miR-122 and liver-related functions and diseases |
| PMC3093880__F9 | Associations among miR-122-identified targets |
| PMC3094097__F3 | Examples of cellular receptors that sense infection and cell death |
| PMC3094203__F3 | Peroxisome proliferator-activated receptor G (PPARG) is a ligand-activated nuclear receptor with potent anti-inflammatory properties that modulates the immune inflammatory response |
| PMC3094296__F1 | KEGG pathways used for the influence approach |
| PMC3094730__F2 | Dendritic cell control of tolerogenic responses |
| PMC3095361__F9 | ROS, elicitor and hormone regulation of O3-induced CRKs |
| PMC3095455__F1 | Schematic representation of the apoptosis signaling pathway that indicates existence of three distinct signaling modules in the apoptotic intrinsic pathway |
| PMC3095674__F4 | Procarcinogenic Effects of Cyclosporine A are Mediated through the Activation of TAK1/TAB1 Signaling Pathway |
| PMC3095763__F1 | Toll-like receptor Signaling in Neural Plasticity and Disease |
| PMC3095770__F2 | Hypothalamic proopiomelanocortin processing and the regulation of energy balance |
| PMC3095949__F3 | Functional pathway analysis of the 28-gene prognostic signature using Ingenuity Pathway Analysis |
| PMC3095999__F2 | Literature-based connections among genes in altered modules of head and neck squamous cell carcinoma (HNSCC) |
| PMC309600__F9 | Working model for Smad6 functions in BMP signaling |
| PMC3096022__F1 | Biochemical pathways leading to the synthesis of TAG and cholesterol |
| PMC3096054__F1 | miRNA biogenesis pathways and regulatory networks |
| PMC3096079__F1 | mTOR regulation pathway involved in hypoxia |
| PMC3096194__F1 | Cell cycle is controlled by the Rb pathway and p53 pathway |
| PMC3096494__F1 | Regulation of Interleukin-10 Gene Expression in Macrophages Engulfing Apoptotic Cells |
| PMC3096496__F6 | Model depicting the generation and consequences of ROS-mediated base damage |
| PMC3096502__F2 | Overview of the NER pathway |
| PMC3096649__F7 | IGF1R Signaling in Ewing Sarcoma Is Shaped by Clathrin-/Caveolin-Dependent Endocytosis |
| PMC3096731__F1 | Eph receptor and mTOR pathway crosstalk: implications for cancer |
| PMC309687__F10 | Postsenescence survival in telomerase-deficient (tlc1ÃŽâ€) budding yeast cells is controlled by three distinct Rad52-based homologous recombination pathways |
| PMC3096978__F4 | Functional network connections between HRneg/Tneg signature genes |
| PMC3097097__F2 | Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term |
| PMC3097115__F5 | PRP-17 and the pre-mRNA splicing pathway are preferentially required for the proliferation versus meiotic development decision and germline sex determination in Caenorhabditis elegans |
| PMC3097389__F1 | CoQ10 biosynthesis pathway |
| PMC3097535__F4 | Global gene expression and Ingenuity biological functions analysis on PCB 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities. |
| PMC3097535__F5 | Global gene expression and Ingenuity biological functions analysis on PCB 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities. |
| PMC3097943__F1 | Role IL-6 signaling in CCA inflammation-related epigenetic regulation |
| PMC3098223__F1 | Integrative Analysis of Transgenic Alfalfa (Medicago sativa L.) Suggests New Metabolic Control Mechanisms for Monolignol Biosynthesis |
| PMC3098671__F2 | Endoplasmic-Reticulum Calcium Depletion and Disease |
| PMC3098789__F6 | Portion of the 'Toll-like Receptor Signaling' pathway for two representative cell lines |
| PMC3098994__F1 | Genetics of Mechanosensation in the Heart. |
| PMC3099033__F9 | Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling |
| PMC3099529__F1 | Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome |
| PMC3099575__F5 | Model of relationship among Hfe, Tmprss6, and the Bmp/Smad signaling pathway in hepcidin regulation |
| PMC3099592__F2 | Activation of mast cells initiates a cascade of events resulting in Th2 polarization and both positive and negative feedback regulatory loops |
| PMC3099707__F10 | Dual MC4R signaling model to account for "rescue" of Ay phenotype by alterations in MC4R trafficking |
| PMC3099728__F8 | Molecular model of Foxo1 and IGF1/insulin regulation of osteocalcin expression |
| PMC3100630__F1 | EGFR biology |
| PMC3100722__F1 | The neuroendocrine (a), limbic (b), and brainstem (c) inter-related, stress-activated corticotropin releasing hormone (CRH) loops |
| PMC3100780__F3 | Integration of BMP, FGF and Wnt signalling at the level of Smad1 during neural induction |
| PMC3101043__F2 | Endogenous and exogenous regulators of TLR activation |
| PMC3101238__F7 | Omeprazole Inhibits Proliferation and Modulates Autophagy in Pancreatic Cancer Cells |
| PMC3101816__F1 | The central role of cIAP1 in NFKB signalling and programmed cell death |
| PMC3101847__F1 | Pathways that regulate aging |
| PMC3101868__F1 | Protein Replacement Therapy and Gene Transfer in Canine Models of Hemophilia A, Hemophilia B, von Willebrand Disease, and Factor VII Deficiency |
| PMC3101870__F1 | Three levels of regulation of the IGF-IR pathwayand its components |
| PMC3102606__F4 | Pathway context for RME modules found in glioblastoma |
| PMC3102695__F5 | Ciliary Neurotrophic Factor Induces Genes Associated with Inflammation and Gliosis in the Retina: A Gene Profiling Study of Flow-Sorted, Müller Cells |
| PMC3102743__F7 | Nodal-Dependent Mesendoderm Specification Requires the Combinatorial Activities of FoxH1 and Eomesodermin |
| PMC3103151__F1 | Intracellular pathway of folate metabolism with highlighted critical pathways of methotrexate (MTX) entry, effect and efflux |
| PMC3103318__F7 | Model pathway for genistein-induced ASAH1 transcription in MCF-7 cells |
| PMC3103347__F5 | Effect of SCGB3A2 on TGFB signaling pathway |
| PMC3103347__F7 | Schematic diagram for the SCGB3A2-induced inhibition of the TGFB signaling pathway |
| PMC3103499__F3 | Computational Identification of Transcriptional Regulators in Human Endotoxemia |
| PMC3103528__F5 | Inhibitory Actions of Anti-Müllerian Hormone (AMH) on Ovarian Primordial Follicle Assembly |
| PMC3103541__F8 | Long-Term Continuous Corticosterone Treatment Decreases VEGF Receptor-2 Expression in Frontal Cortex |
| PMC3103888__F1 | TIRs signaling pathway |
| PMC3103989__F1 | Endocrine, paracrine and autocrine regulation of the IGF-1R pathway and therapeutic strategies for its disruption |
| PMC3104011__F2 | miRNAs regulate DSB DDR through modulating the core protein components of various pathways |
| PMC3104012__F1 | Summary of the common pathways underlying neurodegenerative diseases and cancer that are mediated by miRNAs |
| PMC3104248__F1 | MTOR signaling pathway |
| PMC3104248__F2 | Genetic mutations of signaling molecules implicated in mTOR pathway (red Xs) |
| PMC3104248__F3 | Signaling molecules implicated in epilepsy (see the text for the detail) |
| PMC3104565__F1 | Simplified diagrams for agrin-induced signaling |
| PMC3104579__F1 | RhoA/ROCK I pathway and remodeling of microtubule network underlie the polarization and migration of HSPCs |
| PMC3104724__F2 | This figure outlines the role of KLF10 protein as a target and as a regulator of the TGFBeta-Smad 2,3 signaling pathway |
| PMC3104927__F6 | RHIM-dependent signaling |
| PMC3106121__F1 | Phosphodiesterases and Cardiac cGMP: Evolving Roles and Controversies |
| PMC3106338__F10 | INTERFERON-ALPHA MEDIATES THE DEVELOPMENT OF AUTOIMMUNITY BOTH BY DIRECT TISSUE TOXICITY AND THROUGH IMMUNE-CELL RECRUITMENT MECHANISMS |
| PMC3107100__F1 | Genetic alterations in glioblastoma signal transduction pathways (adapted from Parsons et al) |
| PMC3107200__F8 | Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss |
| PMC3107442__F5 | Transcripts (p < 0.05) involved in cell signaling |
| PMC3107984__F3 | Genetic analysis of biological pathway data through genomic randomization |
| PMC3108053__F1 | Fanconi anemia pathway and ICL repair: implications for cancer therapy |
| PMC3108097__F1 | Iron Homeostasis and the Inflammatory Response |
| PMC3108205__F4 | Delay in apoptosis at 9 hr |
| PMC3108467__F4 | IFN signaling pathway coded with identified proteins on day 7 postinfection |
| PMC3108474__F2 | Membrane type-MMPs regulate vascular cell signaling in cancer |
| PMC3108692__F1 | Mammalian target of rapamycin (mTOR) network |
| PMC3108840__F6 | Functional pathway analysis of glycoproteins overexpressed in PC3-N2 |
| PMC3108840__F7 | Functional pathway analysis of glycoproteins overexpressed in PC3-ML2 |
| PMC3109102__F1 | Basic intracellular molecular pathways regulating MN survival during development |
| PMC3109223__F1 | MTOR signaling pathway |
| PMC3109273__F1 | Host cell death pathways targeted by L |
| PMC3109408__F2 | Simplified diagram of Kynurenine pathway: during neuroinflammation, 95% of the dietary tryptophan is metabolized along the KP within the brain |
| PMC3109492__F2 | Intestinal Effector T Cells in Health and Disease |
| PMC3109507__F1 | Choosing the right path: does DNA-PK help make the decision? |
| PMC3109512__F3 | Proposed role of CnPlc1 in pathogenicity-related signaling in C |
| PMC3109595__F5 | Gene regulatory network model for specification of the skeletogenic mesoderm lineage |
| PMC3109603__F7 | Comparative pathway networks of cyclic genes in mouse, chicken and zebrafish |
| PMC3109859__F6 | Finding Homes for Orphan Cytochrome P450s: CYP4V2 and CYP4F22 in Disease States |
| PMC3109860__F4 | CHK1 Inhibitors in Combination Chemotherapy |
| PMC3109866__F1 | Converging Pathways in Lifespan Regulation |
| PMC3109867__F1 | Insulin/iGF-1 signaling pathway is conserved across phylogeny |
| PMC3110060__F1 | MicroRegulators come of age in senescence |
| PMC3110099__F14 | Schematic diagram to show that knockdown of Akt1 leads to upregulation of Akt2 in response to oxidative stress and its regulation of oxidative-stress-induced apoptosis through three pathways |
| PMC3110186__F5 | Unraveling Molecular Signatures of Immunostimulatory Adjuvants in the Female Genital Tract through Systems Biology. |
| PMC3110626__F1 | Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome |
| PMC3110643__F7 | Cartoon representing CsA-mediated activation of TGF B1-dependent signaling leading to epithelial-mesenchymal transition in epidermoid carcinoma cells |
| PMC3110678__F3 | SAT and PT domains of NSAS in aflatoxin B1biosynthetic pathway |
| PMC3110730__F1 | Wnt signaling and regulation of Beta-catenin in tumorigenesis |
| PMC3110863__F4 | Regulation of MeCP2 expression by Bdnf |
| PMC3110886__F4 | Functional analyses of differentially expressed predicted targets of significantly altered microRNAs |
| PMC3110895__F4 | Modeled miRNA mediated pathways in the pathogenesis of lung fibrosis |
| PMC3110938__F2 | Genome-wide dissection of microRNA functions and co-targeting networks using gene-set signatures |
| PMC3111485__F5 | A Large Gene Network in Immature Erythroid Cells Is Controlled by the Myeloid and B Cell Transcriptional Regulator PU.1. |
| PMC3111669__F2 | BMP signaling and its blocking |
| PMC3111743__F6 | Correlation network among processes with activity modified by both OEA and KDS-5104 treatments is shown |
| PMC3111844__F1 | Overview of Androgen Metabolism Pathway Genes Considered, Including Candidate Genes and Genetic Variants Studied |
| PMC3112285__F2 | Pathway Crosstalk |
| PMC3112459__F1 | TGFB signalling pathway and breast cancer susceptibility |
| PMC3112527__F3 | Summary of the signaling pathway mediated by RET |
| PMC3113646__F6 | TGFBeta-and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR) |
| PMC3113675__F7 | Arginine methylation of G3BP1 regulates both Ctnnb1 mRNA and canonical Wnt/Beta-catenin signaling |
| PMC3113807__F5 | The Interplay between Protein L-Isoaspartyl Methyltransferase Activity and Insulin-Like Signaling to Extend Lifespan in Caenorhabditis elegans |
| PMC3114084__F2 | Titin domain arrangement in the cardiac sarcomere and connectivity within a mechanical signaling network |
| PMC3114309__F1 | The NFAT structure |
| PMC3114474__F1 | Mechanisms of Resistance to EGFR TKIs and Development of a New Generation of Drugs in Non-Small-Cell Lung Cancer. |
| PMC3114846__F5 | Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases |
| PMC3115056__F1 | Regulation of neural process growth, elaboration and structural plasticity by NF-κB. |
| PMC3115268__F2 | A sketch of components involved in HRT-mediated resistance signaling pathway |
| PMC3115327__F3 | Scheme of the signal transduction pathway in response to DNA damage |
| PMC3115623__F5 | Major intracellular signal transduction pathways for CRF1 and CRF2 receptors |
| PMC3115901__F4 | The core biochemical network of the ceramide/sphingosine-1-phosphate rheostat |
| PMC3116035__F3 | A) Schematic outline of mitochondrial and metabolic pathways connected to the PPP in hepatocytes |
| PMC3116046__F2 | Increased expression of DNA repair genes in invasive human pancreatic cancer cells |
| PMC3116111__F1 | Graphical representation of the candidate genes involved in the pharmacodynamics of doxorubicin in a stylized cancer cell |
| PMC3116122__F1 | PI3K pathway activates different processes that regulate proliferation, apoptosis and migration |
| PMC3116140__F2 | The core pathway of Notch signaling |
| PMC3116244__F1 | Signaling Pathways Altered in Hepatic Cancer Stem Cells |
| PMC3116400__F1 | DSBs in S and G2 phases of the cell cycle, collapsed replication forks, and daughter-strand gaps all require HR for their repair |
| PMC3116598__F1 | p21-activated kinases in Erbb2-positive breast cancer. |
| PMC3116645__F1 | Mammalian target of rapamycin (mTOR) signaling pathway |
| PMC3116873__F1 | Oncogenic CagA Promotes Gastric Cancer Risk via Activating ERK Signaling Pathways: A Nested Case-Control Study |
| PMC3117004__F2 | Updated most likely pathway for acylCer formation (November 2010) |
| PMC3117038__F1 | The roles of CARM1 and coactivator methylation in DNA damage signaling pathway |
| PMC3117317__F3 | NFKB signaling pathway |
| PMC3117391__F3 | Pathway for getifinib and docetaxel to generate the synergistic effects on KRT8 |
| PMC3117645__F9 | The miR-29 regulatory network in Zmpste24-/- progeroid mice |
| PMC3117856__F3 | MAPK signaling pathway |
| PMC3117879__F2 | Implications of Relationships between Human Diseases and Metabolic Subpathways |
| PMC3118263__F4 | Pathway analysis links the differentially expressed gene signatures of the MED29 transduced Hs 700T and MIAPaCa-2 cells to a cellular network involved in cell cycle, cancer, and genetic disorder |
| PMC3118279__F2 | Ingenuity Pathway Analysis of epidermal genetic information retrieval-harvested melanoma specimens identifies overexpressed genes involved in melanocyte development and pigmentation |
| PMC3118351__F10 | Pathways by which BrdU impairs epithelial repair and induces persistent inflammation in the chronic NA injury model |
| PMC3118418__F1 | Which FGF ligands are involved in lens induction? |
| PMC3118436__F2 | Metabolic remodeling in cancer cells and regulation by signaling pathways involving oncogenes and tumor suppressor genes |
| PMC3118552__F7 | Activation of the Stress Protein Response Inhibits the STAT1 Signaling Pathway and iNOS function in Alveolar Macrophages: Role of Hsp90 and Hsp70 |
| PMC3118659__F13 | NAD+ biosynthesis and salvage pathways |
| PMC3118679__F1 | The networks of factors (genes product, hormones, and metabolites) potentially involved in the regulation of milk protein synthesis in lactating bovine mammary tissue |
| PMC3118679__F6 | Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 15 relative to -15 d postpartum |
| PMC3118679__F7 | Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 60 relative to -15 d postpartum |
| PMC3118679__F8 | Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 240 relative to -15 d postpartum |
| PMC3118704__F3 | Toll-like receptor-4 (TLR-4) signaling via MyD-88-dependent pathways |
| PMC3118759__F5 | Alteration to activity of the Akt/GSK3B signalling pathway can explain a number of the changes observed in microarray analysis of flies expressing rCAG, rCUG and rAUUCU repeats in the nervous system |
| PMC3119055__F4 | Gene Expression Profiling of Preovulatory Follicle in the Buffalo Cow: Effects of Increased IGF-I Concentration on Periovulatory Events |
| PMC3119055__F5 | Gene Expression Profiling of Preovulatory Follicle in the Buffalo Cow: Effects of Increased IGF-I Concentration on Periovulatory Events |
| PMC3119514__F2 | TNFA and TCR activation pathways |
| PMC3119514__F3 | IL-1 and TLR activation pathways |
| PMC3119514__F6 | RNA polymerase II transcription complex |
| PMC3119520__F7 | Predicted d-galactose network in Y. pestis |
| PMC3119709__F1 | Macrophages as a Battleground for Toxoplasma Pathogenesis |
| PMC3120109__F4 | Schematic illustrating that AMPH indirectly stimulates dopamine (DA), glutamate (glu) and BDNF (B) release and stimulation of D1 dopamine, glutamate, and TrkB receptors, respectively, in the striatum |
| PMC3120887__F5 | MicroRNA Expression Profiling Reveals MiRNA Families Regulating Specific Biological Pathways in Mouse Frontal Cortex and Hippocampus |
| PMC3120937__F1 | Signalling pathways in oesophageal adenocarcinoma |
| PMC3121188__F7 | ERK-dependent signalling during conditioning and extinction of fear |
| PMC3121540__F4 | A gene network shows that mRNA levels of PDGFR and ECM-related genes are significantly correlated in human breast cancer |
| PMC3121598__F10 | The interplay between leptin, IGF-1 and AB42 |
| PMC3121749__F8 | Graded Nodal/Activin Signaling Titrates Conversion of Quantitative Phospho-Smad2 Levels into Qualitative Embryonic Stem Cell Fate Decisions |
| PMC3121779__F15 | Protective effects of OxPLs against acute lung injury and endothelial barrier dysfunction |
| PMC3121899__F3 | Cartoons of PAR-1-dependent signaling by APC and thrombin in endothelial cells when EPCR is either free or occupied by protein C |
| PMC3122057__F8 | Proposed schematic of the roles of NIK and SMG1 in sensitive versus resistant cells in response to SMC and TNFA treatment |
| PMC3122316__F1 | F igure 1.– |
| PMC3122626__F4 | Key cellular signaling cascades regulating morphogenesis in C |
| PMC3122626__F8 | Comparison of cAMP-PKA and MAPK signaling cascades in C |
| PMC3122626__F9 | The calcineurin signaling pathway in C |
| PMC3122959__F1 | Hedgehog signaling in skin cancers |
| PMC3123201__F1 | Plastidial isoprenoid biosynthesis pathway detailing the level of co-expression that PSY shares with individual interrelated isoprenoid biosynthesis pathway genes |
| PMC3123543__F4 | Overlaid networks predicted by the PLS method and generated by IPA pathway designer |
| PMC3123739__F8 | DNA Repair Deficiency in Neurodegeneration |
| PMC3123876__F6 | Profiling experiments and pathway analysis |
| PMC3124103__F1 | Transcription factor NFKB regulates the cellular response to inflammatory and oxidant stress, as well as stretch |
| PMC3124126__F1 | Molecular signaling cascades which normally control mTORC1 activity and may become dysregulated in B-cell lymphomas leading to aberrant mTORC1 signaling activation |
| PMC3124345__F2 | Schematic representation of the possible mechanisms leading to ovarian cysts in female patients with ORD |
| PMC3124359__F1 | Estrogenic effects on gp130 signaling |
| PMC3124472__F4 | Proteomic Analysis of Pathways Involved in Estrogen-Induced Growth and Apoptosis of Breast Cancer Cells |
| PMC3124513__F6 | Integrated Bio-Entity Network: A System for Biological Knowledge Discovery |
| PMC3124653__F1 | Systems pharmacology assessment of the 5-fluorouracil pathway |
| PMC3124653__F6 | Systems pharmacology assessment of the 5-fluorouracil pathway |
| PMC3124877__F1 | Pathway of alcoholic injury resulting in the direct production of oxidative stress and the LPS-TLR pathway that culminates in production of cytokines and other inflammatory processes that result in hepatitis of the liver |
| PMC3125348__F2 | Visual representation of the JA/SA/ET biosynthesis and signaling pathways |
| PMC3125348__F6 | Co-expression network of the ET biosynthesis and signaling pathways |
| PMC3126020__F1 | Hedgehog signaling pathway in vertebrates |
| PMC3126020__F2 | Targeting the Hedgehog pathway in cancer |
| PMC3126106__F3 | Chemosensory processing in the taste - reward pathway |
| PMC3126159__F4 | Temporal regulation of apoptosis in SeV-infected cells by PI3K |
| PMC3127069__F1 | The mTOR-signalling pathway from growth factor receptor through mTOR |
| PMC3127159__F2 | TPO signaling pathway |
| PMC3127162__F8 | E3 ubiquitin ligase-dependent and E3 ligase-independent roles of Rad18 in tolerance of bulky DNA lesions (left) and replication-associated DSB (right) |
| PMC3127207__F2 | Luteolin Effects on Estrogen Signaling Pathway (ESP) Genes |
| PMC3127207__F4 | GenMAPP Diagram of Cell Cycle Pathway Genes Regulated by Luteolin in E2-Treated MCF-7 Cells |
| PMC3127250__F1 | Autophagy and the integrated stress response |
| PMC312742__F9 | Role of E2F1 in the DNA damage response |
| PMC3128083__F9 | RIG-I Mediates Innate Immune Response in Mouse Neurons Following Japanese Encephalitis Virus Infection |
| PMC3128433__F3 | Complement cascade, hemolyisis, and eculizumab |
| PMC3128624__F6 | NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease |
| PMC3128635__F1 | RAS signaling to the PI3K pathway |
| PMC3128635__F2 | Crosstalk and feedback in ERK and PI3K signaling downstream of RAS |
| PMC3128772__F6 | Cell signaling between rNSCs and hMSCs in coculture |
| PMC3128904__F1 | Toll-like receptor (TLR) signaling pathway |
| PMC3128904__F2 | NOD-like receptor (NLR) family and inflammasome |
| PMC3129395__F4 | Molecular model of extranuclear functions of PV in promoting thyroid carcinogenesis via the integrin-FAK-cSrc signaling cascade |
| PMC3129465__F2 | Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies |
| PMC3129504__F2 | Ras/Raf/mitogen-activated protein kinase pathway |
| PMC3129516__F2 | SIRT3 and Cancer: Tumor Promoter or Suppressor? |
| PMC3130144__F6 | Molecular mechanism of autophagy with synthesis of cathepsin D |
| PMC3130335__S1 | MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells |
| PMC3130491__F4 | Schematic of leptin intracellular signaling through the STAT3 and PI3K-PDE3B-cAMP pathways in the hypothalamus |
| PMC3130501__F1 | Intrinsic and extrinsic apoptotic pathways |
| PMC3130677__F3 | Example yeast network |
| PMC3131053__F1 | Differential involvement of IKKB/NFKB signaling in neurons of the hypothalamic arcuate nucleus in the pathogenesis of obesity and hypertension |
| PMC3131055__F1 | Wolbachia-induced responses of specific cell types |
| PMC3131061__F1 | TIR and NFKB signaling pathways |
| PMC3131090__F1 | Negative regulation of the autophagy pathway |
| PMC3131135__F1 | Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection |
| PMC3131157__F6 | Manipulation of plant cell ubiquitin pathway by bacterial pathogens |
| PMC3131208__F2 | Cellular targets of the Tax viral oncoprotein |
| PMC3131208__F4 | NFKB signaling pathways |
| PMC3131451__F1 | The PI3K/mTOR signaling pathway highlighting the phosphorylation sites tested in our cellular and biochemical assays |
| PMC3131688__F1 | Autophagy in immunity and inflammation |
| PMC3131835__F3 | Sphingosine 1-phosphate (S1P) generation and ALI-associated single-nucleotide polymorphism (SNPs) in the S1P biosynthetic pathway |
| PMC3132181__F1 | Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry |
| PMC3132181__F2 | Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry |
| PMC3132189__F4 | Proposed lipid metabolic pathways in Giardia |
| PMC3132554__F2 | Small-molecule inhibitors of the PI3K signaling network |
| PMC3132567__F8 | Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1A Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene Expression |
| PMC3132612__F2 | The major signal transduction pathway in the ER stress response |
| PMC3132641__F3 | Proposed mechanisms mediating the effect of the (pro)renin receptor (PRR) in metanephric kidney development |
| PMC3132733__F1 | Pathway-Based Association Analyses Identified TRAIL Pathway for Osteoporotic Fractures |
| PMC3132735__F7 | CCN2 Is Required for the TGFB Induced Activation of Smad1 - Erk1/2 Signaling Network |
| PMC3133210__F3 | Basic metabolic pathways of E |
| PMC3133219__F1 | Metabolic pathway for purine nucleotide synthesis |
| PMC3133224__F9 | Molecular interplay between FBXL2, its substrate CCTA, and CaM controls phosphatidylcholine (PC) synthesis |
| PMC3133232__F8 | Schematic model of Nrf2 regulation by Keap1 |
| PMC3133259__F1 | The CoA biosynthetic pathway |
| PMC3133356__F7 | Model showing the role for Bmi1 in the DNA damage response pathway |
| PMC3133616__F4 | Functional network of ion channels in T lymphocytes |
| PMC3133775__F2 | Second messengers and membrane trafficking direct and organize growth cone steering |
| PMC3133824__F1 | Cytonuclear signaling pathways in MSNs |
| PMC3133824__F2 | Mechanisms for import and export of proteins to and from the nucleus |
| PMC3133834__F1 | Activation of the Fas/FasL apoptotic pathway by interaction of Fas+ cells with FasL |
| PMC3133882__F4 | Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment |
| PMC3133912__F8 | Bhlhb5 and the Notch signaling pathway |
| PMC3133937__F1 | Concerted regulation of the WNT-DVL-GSK3B signaling pathway in NAc by chronic social defeat stress |
| PMC3134268__F1 | Schematic representation of the influence of photoperiod on deiodinase enzyme gene expression in the hypothalamus |
| PMC3134295__F1 | Apoptotic Process |
| PMC3134325__F1 | Action of ErbB receptor |
| PMC3134378__F2 | Regulation of HIF-1A by the MAPK pathway |
| PMC3134378__F3 | Regulation of HIF-1A by the PI3K pathway |
| PMC3134408__F1 | Proposed molecular pathways in arterial, venous and lymphatic specification in a developing embryo |
| PMC3134613__F6 | Specificity in neuronal activity-regulated gene transcription |
| PMC3134994__F1 | Schematic Illustration: TGF-beta signaling pathway |
| PMC3135176__F2a | Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy |
| PMC3135180__F3 | Convergent stem cell regulatory networks control expression of key stem cell genes |
| PMC3135641__F1 | Metabolic target genes of p53 |
| PMC3135642__F1 | Regulation of metabolism by p53 in proliferating cells |
| PMC3135645__F1 | Coordinated regulation of p53, target of rapamycin (TOR), and insulin/insulin-like growth factor 1 (IGF-1) pathways |
| PMC3135646__F1 | P53 pathway in development, cancer, and reprogramming |
| PMC3135738__F6 | MITOCHONDRIOCENTRIC PATHWAY TO CARDIOMYOCYTE NECROSIS IN ALDOSTERONISM: CARDIOPROTECTIVE RESPONSES TO CARVEDILOL AND NEBIVOLOL |
| PMC3135880__F5 | Survival and proliferative effects of Dilong extract on RSC96 Schwann cell |
| PMC3136091__F1 | Canonical and non-canonical NFKB signalling pathways |
| PMC3136489__F7 | Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood |
| PMC3136489__F10 | Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood |
| PMC3136489__F11 | Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood |
| PMC3136563__F12 | Working model for the role of USP4 in the negative regulation of TNFAlpha-induced TAK1 polyubiquitnation and NFKB activation |
| PMC3136693__F1 | Chemical heme biosynthesis pathway |
| PMC3136711__F2 | Qu on cell cycle |
| PMC3136877__F1 | mTOR signaling cascade in the pathogenesis and prevention of skin cancer |
| PMC3136902__F1 | IL-1RI signaling |
| PMC3136910__F2 | Proposed model of ATF2 regulation of Ha-Ras signaling |
| PMC3136937__F4 | Identification and Analysis of Signaling Networks Potentially Involved in Breast Carcinoma Metastasis to the Brain |
| PMC3137003__F2 | The insulin and leptin-melanocortin signaling pathway is responsible for maintaining energy and metabolic balance by controlling appetite |
| PMC3137012__F8 | Hypothesis of insulin signaling pathways associated with the regulation of CIDEA and CIDEC expression in human adipocytes |
| PMC3137145__F3 | Cigarette smoke exposure induces autophagy and apoptosis |
| PMC3137149__F1 | Simplified model of the tuberous sclerosis complex signaling pathway |
| PMC3137255__F2 | A simplified model for Hh signaling in mammalian cells |
| PMC3137639__F5 | Akt-RSK-S6-kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases |
| PMC3137710__F2 | Chemical 'Jekyll and Hyde's: Small-molecule inhibitors of developmental signaling pathways |
| PMC3137772__F2 | De novo biosynthesis of dolichol phosphate in human |
| PMC3137930__F8 | Analysis of p53 target genes in melanocytes treated with Nutlin-3 for 18 h |
| PMC3137974__F1 | Signal pathway activation by the main TLR and CLR receptors that detect Candida |
| PMC3138369__F1 | Signaling pathway for epidermal growth factor receptor (EGFR) |
| PMC3138532__F1 | HNSCC tumor microenvironment |
| PMC3138544__F1 | Targets and therapies for B-cell non-Hodgkin's lymphoma (B-NHL) within the context of the 10 hallmarks of cancer and overlapping oncogenic signaling pathways |
| PMC3138675__F2 | Molecular mechanisms in hereditary cancer |
| PMC3138766__F6 | JAK2 V617F-Dependent Upregulation of PU.1 Expression in the Peripheral Blood of Myeloproliferative Neoplasm Patients |
| PMC3139189__F1 | Intrinsic pathway of apoptosis |
| PMC3139189__F2 | B1/Fak/Src integrin signaling, cell survival, and suppression of anoikis |
| PMC3139189__F3 | Common pathway of anoikis induction |
| PMC3139406__F7 | Schematic presentation of the potential signaling pathway triggered by RANTES and MCP-1 through CC chemokine receptor 1/3/5 (CCR1/3/5) and CCR2 |
| PMC3139433__F4 | Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes |
| PMC313952__F6 | Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals |
| PMC3139800__F1 | Regulation of endonuclease activity in human nucleotide excision repair |
| PMC3140053__F1 | Genetic Polymorphisms in Inflammation Pathway Genes and Prostate Cancer Risk |
| PMC3140140__F1 | Variation in the suppressive abilities of Wnt antagonists with respect to canonical and non-canonical Wnt signaling pathways |
| PMC3140170__F10 | Nicotine signal transduction pathways |
| PMC3140475__F5 | Proteomic Biomarkers for Acute Interstitial Lung Disease in Gefitinib-Treated Japanese Lung Cancer Patients |
| PMC3140648__F1 | D1 receptor signaling cascades in striatonigral/direct pathway neurons |
| PMC3140692__F3 | Hypoxia regulates other critical pathways that impact tumor progression in a HIF-independent fashion |
| PMC3140958__F6 | Protein interaction maps of the defined ratio clusters, (A) [G1_S]#3 and (B) [G1_S]#2 |
| PMC3141028__F4 | 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation |
| PMC3141076__F6 | Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression |
| PMC3141233__F7 | A model for the role of FANCD2 in Ad replication-dependent recombination |
| PMC3141288__F3 | Roles of NFKB-mediated inflammatory pathway in cellular transformation, cancer survival, proliferation, invasion, angiogenesis and metastasis |
| PMC3141289__F1 | Signaling pathway leading to signal transducer and activator of transcription (STAT)-3 activation (see text for definitions of abbreviations) |
| PMC314152__F7 | LMP1-induced canonical and noncanonical NFKB activation |
| PMC3141633__F3 | Genes identified in the TGF beta pathway |
| PMC3141878__F1 | TLR4 signaling cascade and evidence for modulation by neuropathic pain and opioids |
| PMC3141988__F6 | An E-cadherin-mediated Hippo signaling pathway |
| PMC3142070__F4 | Cause and metabolic consequences of fatty liver |
| PMC3142564__F1 | Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer |
| PMC3142564__F3a | Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer |
| PMC3142627__F1 | Procession to Pediatric Bacteremia and Sepsis: A Series of Covert Operations and Failures in Diplomacy |
| PMC3142679__F1 | Virus reactivation: a panoramic view in human infections |
| PMC3142910__F5 | Schematic representation showing proposed role of TMPRSS6 regulation by the BMP6-SMAD signaling pathway and iron via ID1 |
| PMC3143377__F2 | Molecular Targeted Approaches in Mantle Cell lymphoma. |
| PMC3143377__F3 | Molecular Targeted Approaches in Mantle Cell lymphoma. |
| PMC3143653__F6 | Ingenuity pathway analysis of PKCAlpha-CT regulated, MEF2-targetted cardiac mRNAs |
| PMC3143721__F5 | Putative crosstalk between D1and TrkB receptors in striatal direct pathway neurons controlling PPD mRNA expression |
| PMC3143902__F1 | Inhibition of myostatin (MSTN) and activin signalling by the soluble activin type IIB receptor (ActRIB) |
| PMC3143906__F3 | Multiple factors and pathways affect insulin-like growth factor 1 (IGF1)-Akt signaling |
| PMC3144045__F1 | Signal pathway activation by different surface PRRs |
| PMC3144426__F1 | Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) |
| PMC3144530__F1 | Schematic overview of proposed G protein-coupled oestrogen receptor 1 (GPER1) signalling |
| PMC3144625__F1 | Aryl hydrocarbon receptor signaling pathway |
| PMC3145575__F3 | CSR pathways for primary non-HCC hepatocytes and HCC (Huh7) cell types |
| PMC3145576__F5 | Pathway analysis of proteins detected at elevated concentrations during time course analysis in lung following intratracheal instillation of 20 µg carbon nanoparticles (CNP) |
| PMC3145607__F5 | Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in G1-enriched MCF7 cell cultures |
| PMC3145607__F6 | Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in S-enriched MCF-7 cell cultures |
| PMC3145607__F7 | Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in G2/M-enriched MCF-7 cell cultures |
| PMC3145614__F1 | Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium |
| PMC3145765__F9 | Cardiomyocyte Specific Ablation of p53 Is Not Sufficient to Block Doxorubicin Induced Cardiac Fibrosis and Associated Cytoskeletal Changes |
| PMC3145778__F9 | Redox-Induced Src Kinase and Caveolin-1 Signaling in TGFB1-Initiated SMAD2/3 Activation and PAI-1 Expression. |
| PMC3146004__F4 | Pathway assignment of the important genes based on KEGG |
| PMC3146023__F3 | Human spermatogonial stem cells: a possible origin for spermatocytic seminoma |
| PMC3146054__F2 | Regulation of microsomal triglyceride transfer protein |
| PMC3146245__F2 | Genetic model for nuage assembly and piRNA pathway genes in mice |
| PMC3146511__F6 | Expression and Functional Roles of Angiopoietin-2 in Skeletal Muscles |
| PMC3146606__F2 | PARP function in base excision repair and consequences of PARP inhibition |
| PMC3146625__F1 | Schematic overview of the steroidogenic pathway |
| PMC3146784__F2 | TLR ligands and signalling |
| PMC3146975__F1 | Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1 |
| PMC3146975__F3 | Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1 |
| PMC3147278__F3 | Cross-talk between TLR4 and IL-1 signaling pathways |
| PMC3147301__F3 | Towards an understanding of the adjuvant action of aluminium |
| PMC3147552__F8 | Schematic overview of IDO induction by H |
| PMC3148026__F2 | Pathway alterations involved in the development of low-grade serous carcinoma |
| PMC3148231__F12 | MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus |
| PMC3148240__F1 | Simulating EGFR-ERK Signaling Control by Scaffold Proteins KSR and MP1 Reveals Differential Ligand-Sensitivity Co-Regulated by Cbl-CIN85 and Endophilin |
| PMC3148248__F5 | TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding |
| PMC3148288__F1 | ERM proteins are scaffolds for cAMP signaling pathways |
| PMC3148569__F6 | Perturbed TGFB/Smad and mitogen-activated protein kinase signalling pathways in Dupuytren's fibroblasts |
| PMC3148577__F1 | Metabolic networks of Corynebacterim glutamicum (a) and Brassica napus (b) corresponding to the experimental fluxes measured by [,]and []respectively |
| PMC3148577__F3 | A heterotrophic plant cells |
| PMC3148591__F2 | Major signaling pathways of IPC- and Ipost-mediated protection against cardiac cell death |
| PMC3148653__F3 | Network of TP53-regulated genes |
| PMC3148653__F4 | Network of HNF4A-regulated genes |
| PMC3148828__F4 | KEGG pathway: cell cycle |
| PMC3149005__F6 | Summary of the UPR pathway in rotavirus infected cells |
| PMC3149084__F2 | Single-run analysis of the yeast proteome by LC MS/MS |
| PMC3149098__F6 | GProX Pathway Analysis of the Cellular Response to EGF Stimulation |
| PMC3149150__F2 | Regulation of STEP phosphorylation |
| PMC3149315__F1 | Biosynthetic pathway of GSL and the CIRES procedure |
| PMC3149740__F5 | Mammals have two distinct but ultimately converging pathways to apoptosis |
| PMC3149747__F2 | Extensive feedback and feedforward loops between Ras signaling and miRNAs |
| PMC3149764__F3 | Emerging roles of JAK-STAT signaling pathways in adipocytes |
| PMC3150418__F9 | NFKB signaling participates in both Receptor Activator of NFKB Ligand- (RANKL) and interleukin-4- (IL-4) induced macrophage fusion: Receptor cross-talk leads to alterations in NFKB pathways |
| PMC3151103__F9 | Schematic summary of a signaling pathway underlying IL-1Beta-induced dedifferentiation of primary cultured articular chondrocytes |
| PMC3151145__F1 | Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling |
| PMC3151419__F6 | Regulation of the mTOR signaling pathway by insulin and growth factors |
| PMC3151419__F7 | Regulation of mTOR pathway by Sestrins |
| PMC3151428__F3 | Suppression of anaerobic metabolism by p53 is mediated through multiple pathways |
| PMC3151466__F2 | Rb Pathway and Cancer Therapeutics |
| PMC3151497__F3 | MAPK signaling pathway |
| PMC3151543__F2 | Schematic depiction of how complement modulates T-cell immunity |
| PMC3152294__F1 | Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism |
| PMC3152494__F7 | The crosstalk between the NOTCH and AKT pathways at the molecular and cellular levels |
| PMC3152742__F3 | Proposed lithium's neuroprotective effects against cerebral ischemia |
| PMC3152870__F4 | Signalling pathway of type III interferons (IFNs) compared with type II and type I IFNs |
| PMC3152951__F1 | Interaction between HCV and Nuclear Receptor-mediated Pathways |
| PMC3153009__F3 | Main signaling pathways that mediate visfatin/PBEF/Nampt-induced endothelial cell proliferation and migration |
| PMC3153113__F7 | Hypoxia Induced Energy Stress Regulates mRNA Translation and Cell Growth |
| PMC3153165__F1 | Roles of the NFKB-mediated inflammatory pathway in cellular transformation and in cancer cell survival, proliferation, invasion, angiogenesis, and metastasis |
| PMC3153486__F5 | Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT1) Receptor Blockade |
| PMC3153880__F3 | Schematic representation of the effect of conventional treatment (Conv) and novel treatment (TKIs) on tumor behavior through the EGF-EGFR pathway |
| PMC3153965__F7 | Network representation of altered cellular functions during colonization of the mouse colon by A |
| PMC3154047__F1 | Activation of mammalian target of rapamycin complex 1 (mTORC1) |
| PMC3154190__F5 | Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics |
| PMC3154366__F4 | c-Myc regulates the rate limiting steps at the entry into glycolysis |
| PMC3154417__F2 | mTOR signaling pathway |
| PMC3154472__F1 | Identification and Phylogenetic Analysis of Heme Synthesis Genes in Trypanosomatids and Their Bacterial Endosymbionts |
| PMC3154715__F3 | Working model of relaxin sustained-vasodilatory response |
| PMC3154734__F2 | Protein Folding and Quality Control in the Endoplasmic Reticulum: Recent Lessons from Yeast and Mammalian Cell Systems |
| PMC3154935__F4 | Influence of Stochastic Gene Expression on the Cell Survival Rheostat after Traumatic Brain Injury |
| PMC3155176__F4 | FRAM Is Characterized by Increased Signaling of the BRAF/MEK/ERK Pathway(A) IPA analysis led to the generation of a gene-interaction network of genes differentially expressed in patients |
| PMC3155178__F1 | Synthesis of Dihydrotestosterone via the Classic and Alternative (Backdoor) PathwaysThe classic pathway of steroidogenesis leading to dihydrotestosterone is shown on the left, and the alternative pathway is shown on the right |
| PMC3155287__F1 | Autophagy regulation |
| PMC3155297__F1 | General and organelle-specific stress response pathways influenced by the ageing process |
| PMC3155407__F1 | Murine model of the multiple actions to suppress immune surveillance of exosomes released from neoplastic cells |
| PMC3155635__F3 | Functional pathway analysis of the 12-gene genomic instability signature using Ingenuity Pathway Analysis |
| PMC3156249__F1 | B-Myb, Cancer, Senescence, and MicroRNAs |
| PMC3156300__F9 | Prolactin-Stimulated Activation of ERK1/2 Mitogen-Activated Protein Kinases is Controlled by PI3-Kinase/Rac/PAK Signaling Pathway in Breast Cancer Cells |
| PMC3156642__F1 | Crosstalk between the canonical and non-canonical transforming growth factor-beta1 (TGFB1) and myostatin pathways |
| PMC3156686__F1 | Combining Genome-Wide Association Mapping and Transcriptional Networks to Identify Novel Genes Controlling Glucosinolates in Arabidopsis thaliana |
| PMC3156782__F2 | Wnt/Beta-catenin signaling pathway generated by Ingenuity Pathway Analysis (IPA) |
| PMC3156870__F1 | Resistance to RAF inhibitors in melanoma |
| PMC3157194__F4 | Interaction between MAPK signaling pathway-related genes and miRNAs |
| PMC3157228__F7 | Scheme for changes in the molecular pattern of inflammatory signaling, antigen processing, and presentation in attacked myofibers |
| PMC3157269__F3 | Sensing the HP-PRRSV infection by host cell |
| PMC3157296__F8 | Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth |
| PMC3157425__F4 | Apoptosis Induced by Piroxicam plus Cisplatin Combined Treatment Is Triggered by p21 in Mesothelioma |
| PMC3157546__F7 | The role of TAK1 signaling in bone metastasis |
| PMC3157706__F1 | Molecular pathways in LSCs of CML |
| PMC3157841__F1 | Expression Level Drives the Pattern of Selective Constraints along the Insulin/Tor Signal Transduction Pathway in Caenorhabditis |
| PMC3158334__F1 | Possible mechanisms of opioid receptor mediated influence of morphine on tumor growth |
| PMC3158598__F1 | Representation of PTEN/Akt/mTOR (phosphatase and tensin homolog/Akt/mammalian target of rapamycin) pathway |
| PMC3158628__F1 | Unlinking of the Golgi ribbon during G2 inhibits the recruitment and activation of Aur-A at the centrosome trough a novel mechanism |
| PMC3158739__F1 | Ingenuity pathway analysis (IPA) of CDF driven pathway changes in BxPC-3 cells |
| PMC3158866__F1 | Toll-like receptor signaling pathway |
| PMC3159004__F2 | TLR-independent innate immune responses |
| PMC3159046__F6 | Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood |
| PMC3159098__F2 | Different RNA processing events in mammals |
| PMC3159104__F4 | Extrinsic signal pathways for regulating pluripotency during reprogramming |
| PMC3159106__F2 | TLR-mediated myeloid differentiation primary response gene 88 (MyD88)-dependent and TIR domain containing adaptor inducing interferon (IFN)B (TRIF)-dependent signaling pathways |
| PMC3159106__F3 | TLRs crosstalk with the phosphoinositide 3-kinase (PI3K) signaling pathway |
| PMC3159108__F9 | Putative model integrating lipid peroxidation, phospholipids turnover, AA signaling, and SZ symptomatology |
| PMC3159112__F5 | Ad signaling in endothelial cells |
| PMC3159114__F1 | Modulation of cellular reactive oxygen species (ROS) |
| PMC3159114__F10 | Role of GPx-1 in modulating apoptosis |
| PMC3159175__F1 | Multiple TYRO3-activated pathways signaling pathways converge with transcription or activation of MITF (reproduced from Mitra et al ()), an oncogenic transcription factor often dysregulated in malignant melanoma |
| PMC3159301__F1 | Pathways involved in platelet hyperreactivity in DM patients and therapeutic targets |
| PMC3159521__F2 | Pre-B-cell-receptor signaling is regulated by a feed-back loop via Ikaros and Aiolos |
| PMC3159580__F3 | Not(ch) just development: Notch signalling in the adult brain |
| PMC3159954__F2 | Antiretroviral Therapy Down-regulates Innate Antiviral Response Genes in Patients with AIDS in Sub-Saharan Africa |
| PMC3159954__F3 | Antiretroviral Therapy Down-regulates Innate Antiviral Response Genes in Patients with AIDS in Sub-Saharan Africa |
| PMC3159971__F2 | Mathematical model of dual negative feedback regulation of JAK2-STAT5 signaling |
| PMC3159974__F4 | Predicted synthetic lethal gene pairs in TCA cycle (A), phosphatidylserine biosynthesis (B) and pentose-phosphate pathway (C) |
| PMC3160087__F7 | Model of the role of the Nodal and Cripto signaling pathways in mouse XEN cell differentiation |
| PMC3160099__F7 | Pathways that control the onset of adulthood and the terminal differentiation of specific cell lineages are conserved from C |
| PMC3160197__F1 | Crucial role of EGF signalling augments healthy lifespan in worms |
| PMC3160333__F2 | One Carbon Metabolism in SAR11 Pelagic Marine Bacteria |
| PMC3160745__F1 | PI-3K/Akt signaling pathway |
| PMC3160786__F1 | mTOR signaling pathwayu2003The scheme depicts mTOR signaling cascade in the regulation of energy and growth factor-dependent translation and autophagy |
| PMC3160786__F2 | Amino acids sensing of mTORC1u2003Rag-Ragulator-dependent mTORC1 activation in response to amino acid |
| PMC3160828__F1 | More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases |
| PMC3161051__F7 | Rad6B/Beta-catenin regulation in breast cancer cells with autocrine Wnt activity |
| PMC3161159__F1 | Retinoid metabolic pathway |
| PMC3161420__F1 | Regulation of apoptosis by the BCL-2 family |
| PMC3161675__F3 | Signal Transduction Involving the Dmp1 Transcription Factor and its Alteration in Human Cancer |
| PMC3161734__F3 | Predicting the Physiological Role of Circadian Metabolic Regulation in the Green Alga Chlamydomonas reinhardtii |
| PMC3161872__F1 | Summary of TNFR signalling |
| PMC3161973__F1 | Putative mogrosides biosynthesis pathway in Siraitia grosvenorii |
| PMC3162305__F4 | Oncostatin M signaling pathway |
| PMC3162452__F7 | Schematic representation of intracellular pathways implicated in the regulation of cholesterol homeostasis and inflammatory response in human macrophages by IL-6 |
| PMC3163125__F1 | Complement system: the classical complement pathway involves a sequentially acting multistep cascade in which the complement components C1q, C1s, C1r, C4, C2, and C3 play important roles |
| PMC3163143__F2 | Schematic presentation of molecular changes associated with N-Myc amplification in neuroblastoma |
| PMC3163143__F3 | Genomic and non-genomic actions of all-trans retinoic acid (ATRA) |
| PMC3163259__F1 | Wnt/Beta-catenin signalling in the absence and presence of Wnt stimulus |
| PMC3163574__F2 | Identification and Visualization of CD8+ T Cell Mediated IFNG Signaling in Target Cells during an Antiviral Immune Response in the Brain |
| PMC316360__F6 | Interphase/S phase omission between the two meiotic divisions |
| PMC3163738__F3 | IFNA (type-I IFN) and IFN-λ (type-III IFN) signal through distinct receptor complexes, but activate the same intracellular signaling pathway |
| PMC3163765__F2 | Signal Transducer and Activator of Transcription 5a/b: Biomarker and Therapeutic Target in Prostate and Breast Cancer |
| PMC3163776__F2 | IRE1Alpha-XBP1 pathway in inflammation |
| PMC3163776__F3 | IRE1Alpha-XBP1 pathway in glucose homeostasis |
| PMC3163779__F1 | Thyroid hormone action is modulated by the deiodinases |
| PMC3163839__F2 | Sirt1 activity as it relates to AD etiology |
| PMC3163839__F3 | Progression of amyloidogenesis in parahippocampal region and hippocampal formation of mediotemporal lobe |
| PMC3163944__F7 | Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice |
| PMC316396__F7 | Axial and appendicular cartilage |
| PMC3164150__F2 | Insulin-like growth factor 1 receptor (IGF-1R) signaling pathway |
| PMC3164321__F1 | KEAP1 Cullin-3 E3-ubiquitin ligase complex and its roles in maintaining cellular levels of NRF2 and IKBKB |
| PMC3164457__F5 | Mi-2/NuRD complex depletion in germinal center B cells leads to alterations in chromatin, checkpoint activation, and delayed progression through S phase |
| PMC3164671__F5 | Genome-Wide Identification of Bcl11b Gene Targets Reveals Role in Brain-Derived Neurotrophic Factor Signaling |
| PMC3164695__F7 | The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO |
| PMC3164721__F1 | Phospholipase C Isozymes Are Deregulated in Colorectal Cancer - Insights Gained from Gene Set Enrichment Analysis of the Transcriptome |
| PMC3164770__F2 | Impact of Genetics on the Diagnosis and Treatment of Renal Cancer |
| PMC3164770__F5 | FLCN pathway |
| PMC3164983__F1 | mTOR inhibitors in renal cell carcinoma |
| PMC3165008__F1 | An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis |
| PMC3165056__F4 | Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity |
| PMC3165102__F1 | TGFB/SMAD/GLI2 signaling axis in cancer progression and metastasis |
| PMC316535__F6 | Genetic models for ptp-2 signaling during (A) oogenesis and (B) vulval development |
| PMC3165467__F6 | Results of Ingenuity pathway analysis |
| PMC3165779__F3 | Cellular PA-interaction networks |
| PMC3165799__F1 | Schematic diagram of the ER stress response |
| PMC3166148__F3 | The citric acid cycle pathway (reprinted from KEGG []) |
| PMC3166203__F10 | Different ways to activate NFKB |
| PMC3166203__F12 | Upstream kinases and redox-sensitive phosphatases in NFKB activation |
| PMC3166203__F13 | Redoxosome formation in IL-1 signaling |
| PMC3166354__F1 | Cellular and Molecular Action of the Mitogenic Protein-Deamidating Toxin from Pasteurella multocida |
| PMC3166463__F1 | RIGI-like receptor pathway |
| PMC3166463__F3 | Innate immune signalling at the mitochondria |
| PMC3166557__F2 | Planar Cell Polarity Pathway - Coordinating morphogenetic cell behaviors with embryonic polarity |
| PMC3166778__F1 | PI3K signalling pathway: The phosphatidylinositol 3-kinase (PI3K) signalling pathway begins with PI3K activation by receptor tyrosine kinases after growth factors or insulin stimulation |
| PMC3166863__F5 | NPHP4 antagonizes the Hippo pathway |
| PMC3167094__F1 | New Hormonal Therapies for Castration Resistant Prostate Cancer |
| PMC3167192__F1 | Molecular basics of tumor angiogenesis |
| PMC316759__F5 | Regulation of reproductive growth and metabolism by the DAF-2 insulin receptor-like signaling pathway |
| PMC316768__F1 | Model of somatic sex determination in C |
| PMC3167888__F6 | Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages |
| PMC3168472__F5 | Insights into Eyestalk Ablation Mechanism to Induce Ovarian Maturation in the Black Tiger Shrimp |
| PMC3168677__F2 | MicroRNAs in Rheumatoid Arthritis |
| PMC3168773__F2 | Functional relationship linking Crb proteins to the SWH pathway |
| PMC3169181__F2 | Crosstalk between host autophagy and viruses |
| PMC316921__F6 | Wnt signaling in the early C. elegans embryo |
| PMC316922__F7 | Models for the possible action of FAR1 |
| PMC3169412__F1 | Fatty-acid biosynthetic pathway for R |
| PMC3169508__F2 | An indirect interaction between the Axon Guidance and Insulin Signaling pathways in the network for the comparison between HF and LF diet at t = 0 |
| PMC3169508__F3 | Pathway interactions and detailed network visualization for the interactions with three apoptosis related pathways for the comparison between HF and LF diet at t = 0 |
| PMC3169542__F7 | Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD |
| PMC316957__F9 | How ECSIT may participate in Toll/IL-1 signaling |
| PMC3169577__F1 | Evolution of the TGFB Signaling Pathway and Its Potential Role in the Ctenophore, Mnemiopsis leidyi |
| PMC3169732__F6 | Schematic diagram illustrating the proposed signaling pathway involved in cigarette smoke extract-induced increase in expressions of inflammatory genes in airway smooth muscle cells |
| PMC3169997__F1 | Epithelial cell cycle arrest in G2/M and epigenetic changes in fibroblasts coordinately promote kidney fibrosis |
| PMC3170087__F2 | dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity |
| PMC3170087__F4 | dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity |
| PMC3170128__F5 | Innate and adaptive immune responses to cell death |
| PMC3170448__F5 | Simply comparing and contrasting the expression patterns of perturbed genes was inadequate for deciphering the MAPK pathway response dynamics |
| PMC3170456__F1 | Autophagy in Cancer: Therapeutic Implications |
| PMC3170587__F2 | Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma. |
| PMC3170700__F1 | Activation of cellular responses during ER stress |
| PMC317073__F7 | Regulation of TNF-R1signaling pathways during apoptosis |
| PMC3170851__F2 | The Multifaceted Roles of Autophagy In Tumors--Implications For Breast Cancer |
| PMC3170890__F1 | IL-10 signal transduction and hypothesized treatment by dual gene therapy |
| PMC317132__F1 | Model of somatic sex determination in C |
| PMC3171365__F2 | Bayesian network fits for mutation data for cycle checkpoint II pathway using (a) Minimum Spanning Tree algorithm (maximum indegree of 1); (b) Bayesian Information Criterion (maximum indegree of 2) |
| PMC3171365__F3 | Bayesian network fits for wildtype data for cycle checkpoint II pathway using (a) Minimum Spanning Tree algorithm (maximum indegree of 1) |
| PMC3171509__F1 | This figure illustrates the core TSC-mTor pathway, as discussed in the text |
| PMC3171706__F1 | G1/S transition and G1/S checkpoint induction |
| PMC3171706__F3 | G2/M transition and G2/M checkpoint induction |
| PMC3171751__F3 | Altered gene expression during pressure overload hypertrophy |
| PMC317204__F8 | Schematic diagram illustrating a model for the antagonistic roles of Dp110 and DPTEN in Drosophila growth control |
| PMC3172097__F1 | Autophagy pathway in plants |
| PMC3172101__F1 | New additions to the Hippo pathway in flies (a) and man (b) |
| PMC3172156__F2 | RLR signaling pathway showing RIG-I bound to ligand RNA and signaling downstream to IRF-3 and NF-kB to induce IFNA/B production from a virus-infected cell |
| PMC3173057__F11 | Schematic view of the proposed HSP60-TLR4 signaling in response to myocardial ischemia |
| PMC317355__F3 | Wnt-signaling pathway |
| PMC317355__F6 | TGFB signaling in normal colonic epithelium and cancer cells |
| PMC3173728__F1 | In this figure we show the two main pathways to apoptosis, and their interaction through the molecule BID, since death receptors activate the intrinsic pathway by activating BID |
| PMC3173800__F2 | Two major pathways to caspase activation in vertebrates: the death receptor or extrinsic pathway, engaged by the indicated members of the TNF receptor family on the cell surface, and the Bcl-2-regulated mitochondrial or intrinsic pathway |
| PMC3174148__F4 | Predictive Power Estimation Algorithm (PPEA) - A New Algorithm to Reduce Overfitting for Genomic Biomarker Discovery |
| PMC3174190__F2 | Autism-Associated Gene Expression in Peripheral Leucocytes Commonly Observed between Subjects with Autism and Healthy Women Having Autistic Children |
| PMC3174204__F6 | Conserved Regulation of p53 Network Dosage by MicroRNA-125b Occurs through Evolving miRNA-Target Gene Pairs |
| PMC3174208__F1 | Comprehensive Association Analysis of Homocysteine Metabolic Pathway Genes in Singaporean Chinese with Ischemic Stroke |
| PMC3174390__F1 | TGFB/Smads and crosstalk pathways in renal fibrosis and inflammation |
| PMC3174390__F4 | Inhibitory role of Smad7 in renal fibrosis and inflammation |
| PMC3174756__F6 | CDK5 (A) and actin (B) signaling pathway in primary neurons |
| PMC3174986__F3 | Plasmodium falciparum-Infected Erythrocytes and IL-12/IL-18 Induce Diverse Transcriptomes in Human NK Cells: IFNA/B Pathway versus TREM Signaling |
| PMC3175103__F4 | Dysregulated TRK Signalling is a Therapeutic Target in CYLD Defective Tumours |
| PMC3175149__F1 | IL-33 release and signaling via ST2L |
| PMC3175442__F2 | Map of pentose phosphate pathway (Genego Metacore) overlapped with quantile-normalized estimations of protein abundance |
| PMC3175442__F4 | Map of cytoskeleton remodeling pathway (Genego Metacore, fragment) overlapped with quantile-normalized estimations of protein abundance |
| PMC3175541__F7 | NK2 homeobox 1 (NKX2-1)-Sam Pointed Domain Ets-like Factor (SPDEF)-associated gene network analyzed using Ingenuity Pathway Analysis |
| PMC3175556__F7 | Schematic diagrams of the signal transduction in TCDD-induced MUC5AC gene expression and the conventional AhR pathway in the activation of CYP1A1 expression |
| PMC3175563__F6 | Proposed mechanism of mechanical stress-induced activation of EGFR pathway in murine tracheal epithelial cells |
| PMC3175613__F3 | Proposed in vivo innate and adaptive immune responses to AAV vectors |
| PMC3175639__F2 | Clock-cancer connection in Non-Hodgkin's Lymphoma: a genetic association study and pathway analysis of the circadian gene Cryptochrome 2 |
| PMC3175712__F1 | (A-C) Schematics of Wnt signaling components in the absence of a Wnt signal (A), the presence of a Wnt signal (B), and the presence of a Wnt signal blocked by the displacement of Tcf7l2 by dnTcf7l2 (C) |
| PMC3175721__F6 | Models for context-dependent ICL repair during replication |
| PMC3175751__F2 | Schematic Overview of Nodal and Cripto-1 Signaling Pathways |
| PMC3176054__F5 | Proposed model of early pathologic events occurring in the lacrimal glands of C57BL/6.NOD-Aec1Aec2 male mice defined by changes in gene expression |
| PMC3176306__F1 | New strategies in Prostate Cancer: targeting lipogenic pathways and the energy sensor AMPK |
| PMC3176897__F1 | Summary of fatty acid and glucose metabolism |
| PMC3177043__F2 | Different pathways of myostatin signalling |
| PMC3177269__F4 | Proposed model for a common symbiotic signaling pathway between actinorhizal plants and legumes |
| PMC3177306__F2 | The canonical vertebrate Wnt signaling pathway |
| PMC3177572__F6 | Schematic diagram summarizing the bidirectional role of PIAS1 in regulating JNK-dependent oxidative stress responses |
| PMC3177754__F4 | RIG-I Like Receptors and Their Signaling Crosstalk in the Regulation of Antiviral Immunity |
| PMC3177871__F1 | The metabolic pathway converting serotonin to melatonin involves the enzymes AANAT and ASMT (previously known as HIOMT) |
| PMC3178084__F2 | Runx2-deficient cells exhibit suppression of genes by insulin at multiple stages of the signaling pathway |
| PMC3178285__F5 | Proposed signaling of TNFA- and leptin-induced EL upregulation in primary placental ECs |
| PMC3178431__F6 | p63 signaling in cancer cells |
| PMC3178610__F5 | Determining Signalling Nodes for Apoptosis by a Genetic High-Throughput Screen |
| PMC3179275__F4a | Integrative computational biology for cancer research |
| PMC3179548__F2 | PE intoxication pathway |
| PMC3179812__F6 | Stem Cell Marker (Nanog) and Stat-3 Signaling Promote MicroRNA-21 Expression and Chemoresistance in Hyaluronan/CD44-activated Head and Neck Squamous Cell Carcinoma Cells |
| PMC3179879__F5 | Abrin (ABR)-triggered apoptosis |
| PMC3179880__F2 | Functional role of skeletal muscle-derived neurotrophic factors after exercise |
| PMC3179938__F3 | Top IPA generated network |
| PMC3179949__F6 | A schematic representation showing 17Beta-estradiol inhibition of uPA and MMP-9 expression, and cell motility via suppression of JNK1/2 pathway in human LoVo colon cancer cells |
| PMC3180046__F2 | NFKB signaling pathways |
| PMC3180062__F8 | Schematic Model of apoptotic signaling induced by targeting EphA2 gene by siRNA in MMC |
| PMC3180107__F1 | Intrinsic and extrinsic pathways of apoptosis |
| PMC3180107__F2 | Molecular mechanism of autophagy and its role in cell death and survival |
| PMC3180192__F2 | TGFB pathway genes in iMYC cells |
| PMC3180262__F8 | Hypothetical molecular signaling pathways of the expression of p27 by which moderate increase in the concentration of D-(+)-glucose down-regulates and deficiency of D-(+)-glucose or L-leucine up-regulates the expression of p27 |
| PMC3180377__F9 | Toll-Like Receptor 2 Pathway Regulates the Ppargc1a/b Metabolic Co-Activators in Mice with Staphylococcal aureus Sepsis |
| PMC3180440__F2 | Regulation of the early myogenic transcriptional program by the kinome |
| PMC3180440__F3 | Regulation of the late myogenic transcriptional program by the kinome |
| PMC3180573__F1 | Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke |
| PMC3180702__F6 | Transcriptional complexity of the mesenchymal-epithelial transition network |
| PMC3180925__F1 | Wnts signal through a "canonical" pathway involving Beta-catenin mediated transcriptional regulation (at left) and through "non-canonical" pathways involving calcium and Rac/JNK-mediated signaling (at right) |
| PMC3181038__F1 | Signaling the unfolded protein response: Three proximal sensors IRE1, PERK, and ATF6 regulate the UPR through their respective signaling cascades |
| PMC3181077__F1 | NFKB activation pathways and the impact of S-glutathionylation |
| PMC3181220__F3 | Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma. |
| PMC3181269__F1 | Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis and Signaling |
| PMC3181439__F1 | Jun N-terminal kinase signaling pathway |
| PMC3181488__F2 | Signal-receiving cell–modulation of developmental signalling by intracellular trafficking |
| PMC3182268__F1 | Apoptotic pathway to cell death from the perspective of the Bcl-2 family of proteins.1, The intrinsic pathway is initiated by various signals, principally extracellular stimuli |
| PMC3182762__F1 | TLR signaling pathways |
| PMC3183072__F6 | Activation of Wnt5/Calmodulin Signalling Pathway. |
| PMC3183286__F2 | The role of sphingosine kinase localization on substrate utilization and delivery of S1P to specific sites for secretion or loading of intracellular effectors |
| PMC3183400__F4 | New Insights into insulin resistance in the diabetic heart |
| PMC3183592__F1 | Normal hepatic methionine metabolism |
| PMC3184062__F9 | Scheme for poly(I:C)-induced apoptotic signaling pathway in high TLR3-expressing NB cells (left panel), but not low TLR3-expressing NB cells (right panel) |
| PMC3184251__F1 | Smac mimetics and TNFA: a dangerous liaison? |
| PMC3184252__F6 | Pathways of androgen biosynthesis |
| PMC3184987__F5 | Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component |
| PMC3185015__F9 | RSPO1/Beta-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary |
| PMC3185234__F1 | Enterohepatic circulation of the bile |
| PMC3185489__F1 | Diagram connecting the insulin pathway and fatty acid (FA) biosynthesis |
| PMC3185489__F2 | Some of the effects brought about by HCV on insulin signaling in hepatocytes |
| PMC3185489__F4 | The effects of HCV on steatosis development |
| PMC3185509__F1 | Activation of antiviral and proinflammatory responses during HSV infections |
| PMC3185509__F3 | Innate immune evasion mechanisms of HSV |
| PMC3185522__F3 | HCV induces the over-expression of PP2Ac via an ER stress response pathway |
| PMC3185527__F3 | Illustration of the type I IFN signaling pathway and its inhibition by the henipavirus P, V and W proteins |
| PMC3185539__F1 | Summary of NSP1 inhibition of the innate immune response pathway |
| PMC3185579__F3 | TLR-dependent and independent IFN-I induction, signaling and action |
| PMC3185585__F1 | Remodeling the cellular secretory pathway to support enterovirus replication |
| PMC3185594__F8 | Signaling pathways involved in JSRV Env-induced cell transformation |
| PMC3185611__F1 | PRRs involved in detecting flaviviruses |
| PMC3185660__F2 | The biosynthetic pathway of type 1 (Lc) and type 2 (nLc) HBGAs |
| PMC3185699__F1 | Proposed signaling pathway to the actin cytoskeleton during HIV-1 entry in T lymphocytes |
| PMC3185727__F1 | Illustration of the endogenous RNAi pathway and therapeutic mimics |
| PMC3185763__F1 | Extrinsic (death receptor-mediated) and intrinsic (mitochondria-mediated) pathways that lead to apoptosis of HIV infected helper T cells |
| PMC3185772__F2 | Regulation of Blood-brain barrier permeability, entry of WNV in the brain and factors involved in the pathogenesis of WNV-induced neuroinvasisve disease |
| PMC3185786__F1 | Survival pathways controlled by Tax |
| PMC3185810__F1 | Interplay between HTLV-1 and the type-I interferon (IFN-I) induction pathway |
| PMC3185810__F2 | Alteration of the IFN-I signaling pathway by HTLV-1 |
| PMC3186011__F1 | Cell surface and endosomal recognition of viruses by Toll-like receptors (TLRs) |
| PMC3186046__F1 | S1P receptor subtype-specific heterotrimeric G protein coupling and intracellular signaling mechanisms |
| PMC3186711__F8 | A model of the role of TLR4 signaling pathways in regulating TNFA expression |
| PMC3186860__F7 | Notch1 Regulates the Effects of Matrix Metalloproteinase-9 on Colitis-Associated Cancer in Mice |
| PMC3186862__F1 | BAD pathway in genes associated with induced cisplatin-resistance |
| PMC3187166__F1 | Selected part of the central metabolism in C |
| PMC3187613__F5 | Signaling pathways that regulate mammalian autophagy |
| PMC3187694__F1 | Simplified model of autophagy |
| PMC3187860__F1 | Brain Arteriovenous Malformation Pathogenesis: A Response-to-Injury Paradigm |
| PMC3187864__F6 | Axon viability depends on coordinated endocytic trafficking and signaling |
| PMC3187934__F2 | Phosphorylation pathways adapted from KEGG (50)(51) |
| PMC3188357__F2 | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), is the major genotoxic heterocyclic amine generated from cooking meats at high temperatures |
| PMC3188430__F7 | miR-486 is an important regulator of PTEN/AKT signaling in normal and dystrophic muscle |
| PMC3188673__F5 | Vitamin D Metabolism and Function in the Skin |
| PMC3188682__F3 | TGFB1/SMAD3 signaling as an integrator of fibrotic mechanisms in the kidney |
| PMC3188704__F1 | Regulation of cell migration by signaling endosomes |
| PMC3188749__F3 | Simplified schematic presentation of the transcriptional hierarchy of essential factors and signaling pathways during endocrine specification of the pancreatic endoderm |
| PMC3188880__F2 | Stat3 interactions in glioma biology |
| PMC3188957__F4 | Highest confidence network of genes influenced by CLOCK knockdown |
| PMC3189169__F1 | Toll-like receptor (TLR) and type I interferon (IFN) signaling pathways |
| PMC3189824__F2 | Schematic model for the activation of NFKB signaling pathways |
| PMC3189826__F1 | p130Cas and p140Cap signalling involved in migration and invasion |
| PMC3189826__F7 | Signaling pathways leading to 3D invasion of ErbB2 transformed MCF10 cells over-expressing p130Cas |
| PMC3189939__F3 | CAFET Algorithm Reveals Wnt/PCP Signature in Lung Squamous Cell Carcinoma |
| PMC3190105__F1 | TLR-dependent and JAK/STAT-dependent signaling pathways in microglia |
| PMC3190192__F1 | PRL crosstalk with estrogen, progesterone, EGF/TGFA, and IGF-I |
| PMC3190874__F1 | Immunoglobulin E Receptor Signaling and Asthma. |
| PMC3190874__F2 | FcERI signaling pathway is negatively regulated by a number of cell surface and intracellular proteins that act at various points in the FcERI signaling network |
| PMC3190890__F7 | The signaling pathway of EpCAM complex proteins in the regulation and enhancement of OSKM-mediated pluripotency reprogramming |
| PMC3191034__F7 | Postulated model for GRTH negative autocrine molecular mechanism of regulation of androgen synthesis in Leydig cells |
| PMC3191051__F9 | Model for TGFB1-mediated signaling to the miR143/145 regulatory region |
| PMC3191464__F2 | Model depicting the pathway of TGFBeta-mediated Bim regulation and apoptosis |
| PMC3191732__F1 | Cyclooxygenase pathway of AA metabolism |
| PMC3192015__F1 | Mammalian target of rapamycin, Akt, and phosphatidylinositol 3-kinase signaling |
| PMC3192251__F2 | NPC and CF converge on multiple intracellular trafficking pathways |
| PMC3192435__F2 | Targeting the PI3K/Akt/mTOR pathway to treat lymphoma |
| PMC3192752__F5 | Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment |
| PMC3192838__F7 | Hepatitis C Virus Reveals a Novel Early Control in Acute Immune Response |
| PMC3192861__F10 | A schematic model of GC-mediated acute activation of NHE3 via SGK3 |
| PMC3192911__F2 | Therapeutic tol-DC in organ allotransplantationTol DC can be either recipient- or donor-derived (in the case of living-donor transplantation) |
| PMC3193242__F7 | The cross-talk between IKK family members in the MyD88 signaling pathway |
| PMC3193279__F1 | VEGF Signaling Pathway within endothelial cells |
| PMC3193288__F1 | Innate immunity against RNA viruses in mammals |
| PMC3193400__F2 | Activation of NFKB and regulation of downstream transcriptional antioxidant and pro-oxidant targets |
| PMC3193402__F2 | Crosstalk between RANKL- and TNF-induced NFKB signaling in OCs |
| PMC3193404__F1 | NFKB signaling pathways initiated by TLR4, TCR, TNF receptor 1, CD40 and genotoxic stress |
| PMC3193406__F1 | Canonical and non-canonical NFKB signaling pathways |
| PMC3193406__F2 | Positive and negative domains regulating p100 processing |
| PMC3193406__F3 | NIK stabilization as a mechanism of non-canonical NFKB signaling |
| PMC3193407__F1 | NFKB activation by the canonical pathway |
| PMC3193409__F4 | Expanding role of ubiquitination in protein kinase activation in diverse NFKB pathways |
| PMC3193426__F1 | DSB repair pathways and SUMO |
| PMC3193436__F1 | Model describing the proposed role of Rap1GAP in the control of GDNF-induced Ret signaling |
| PMC3193452__F1 | Regulated necrosis in the intestine of FADDIEC-KO mice |
| PMC3193469__F4 | Simplified cartoons illustrating the components of the cullin-RING E3 ligases (CRLs) |
| PMC3193469__F5 | GA signaling pathway in rice and Arabidopsis |
| PMC3193469__F6 | Model of GA-induced DELLA protein degradation and the regulation of PIF protein function |
| PMC3193487__F1 | Schematic of crosstalk between TLR pathway and MHC molecules |
| PMC3193496__F1 | Two conserved branches of the canonical Wnt pathway |
| PMC3193496__F2 | HIPK2 and NLK/LIT-1 in Wnt signaling |
| PMC3193496__F4 | Context-dependent function of HIPK2 in Wnt signaling |
| PMC3193874__F2 | Caloric Restriction and Chronic Inflammatory Diseases |
| PMC3193940__F2 | An array of cellular stressors can perturb the folding environment in the endoplasmic reticulum (ER) leading to unfolded or misfolded protein |
| PMC3194179__F2 | Ingenuity Pathway Analysis identified ERK as the Top network signaling Hub where the shaded shapes indicate the candidate genes from the present study |
| PMC3194179__F3 | Ingenuity Pathway Analysis identified MapK as second Top network signaling Hub where the shaded shapes indicate the candidate genes from current study |
| PMC3194179__F4 | Ingenuity Pathway Analysis identified NFKB as the Top Network signaling Hub where the shaded shapes indicate the candidate genes from the present study |
| PMC3194221__F2 | 1,25(OH)2D3 intracellular signalling pathway |
| PMC3194983__F1 | Inhibition of the type I interferon (IFN) induction and signaling pathways by viral proteins of KSHV |
| PMC3195192__F2 | VEGF-VEGFR signaling in lymphangiogenesis |
| PMC3195227__F1 | A schematic diagram of the kynurenine pathway |
| PMC3195649__F2 | Targeted therapies for breast cancer |
| PMC3195753__F3 | Comparative analysis of plastid transcriptomes in cucumber |
| PMC3196026__F2 | The outcome of transplantation is determined by cosignalling |
| PMC3196058__F2 | Dynamic Role of Beta-Catenin in Synaptic Plasticity |
| PMC3196095__F6 | Proposed model |
| PMC3196116__F10 | Proposed model shows the requirement of the IL-4RAlpha-Jak2-mediated signaling pathway for IL-13-induced M2 gene expression in human monocytes/macrophages |
| PMC3196210__F2 | Relationships of different neurons in the striatum and neurotransmitter signaling involved in interval timing |
| PMC3196283__F1 | BER pathways BER is initiated by a damage specific DNA glycosylase and APE1 that excise the damaged base and incise the arising abasic site, respectively generating a DNA single strand break with a 5'-sugar phosphate |
| PMC3196377__F6 | Regulator of G Protein Signaling 6 (RGS6) Mediates Doxorubicin-induced ATM and p53 Activation by a Reactive Oxygen Species (ROS)-dependent Mechanism |
| PMC3196718__F4 | Network of upregulated genes in C2C12 cells treated with rhBMP2 and rhBMP7 using the STRING 9.0 pathway analyzer |
| PMC3196888__F8 | A model showing the overlapping functions of MMR and FA proteins in ICL and MMR |
| PMC3197200__F2 | Intracellular signaling pathways regulating growth |
| PMC3197364__F6 | Hypothesized mechanisms for sphingolipids in cardioprotective signaling in response to ischemia or hypoxia |
| PMC3197649__F3 | Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes |
| PMC3197649__F6 | Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes |
| PMC3197858__F1 | Fatty acid synthase as a potential therapeutic target in cancer |
| PMC3198061__F3 | In individuals with high macrophage aggregation around dead adipocytes as CLS, activation stimuli such as IL-1, lipopolysaccharide (LPS) and lipopolysaccharide binding protein (LBP), and TNFA bind to their appropriate membrane receptors |
| PMC3198763__F2 | MTORC1 pathway controls cellular metabolism |
| PMC3198803__F5 | CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae |
| PMC3198803__F7 | CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae |
| PMC3198893__F4 | One of the networks of genes commonly induced in both dendritic cells and macrophages when infected by bacteria, in both human and mouse |
| PMC3198893__F5 | One of the networks of genes strongly induced in dendritic cells but less so, unchanged, or suppressed in macrophages |
| PMC3198933__F1 | Toll-like receptor (TLR) signaling |
| PMC3199248__F1 | TLR induction of inflammation by parasitic infection |
| PMC3199279__F2 | Metabolic interactions between folates and vitamins B12, B6, and B2 |
| PMC3199545__F1 | Schematic diagram illustrating some of the major abnormalities related to sensitized D1R-signaling and associated to LID |
| PMC3199787__F4 | Graphical representation of the IL-6 signaling pathway reveals significant gene expression changes following sarin-induced seizure |
| PMC3199809__F1 | The TGFB signaling pathway |
| PMC3199966__F1 | Schematic biosynthetic pathways for the major phospholipid (Kennedy Pathway) and sphingolipid classes biosynthesized in mammalian cells and observed in MALDI IMS of mammalian tissues |
| PMC3200079__F3 | Homeostatic and leukemic expression of receptors, signaling proteins, and transcription factors along the B cell pathway |
| PMC3200485__F2 | RGS14 at the interface of hippocampal signaling and synaptic plasticity |
| PMC3201689__F1 | Diagram illustrating the DNA base excision repair (BER) pathway |
| PMC3201744__F1 | MiR-21, miR-126, and miR-148a directly or indirectly regulate DNMT1 in SLE CD4+ T cells.A |
| PMC3201973__F9 | Toll-like Receptor 3 Regulates Neural Stem Cell Proliferation by Modulating the Sonic Hedgehog Pathway |
| PMC3202104__F2 | EBV infection impacts on cell death and survival pathways in GC B cells |
| PMC3202302__F1 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202302__F2 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202302__F4 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202302__F5 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202514__F1 | Maturational changes in fatty acid and carbohydrate metabolism gene expression |
| PMC3203219__F1 | Costimulatory pathways relevant in transplantation |
| PMC3203325__F2 | XPC: Implications in cancer and oxidative DNA damage |
| PMC3203674__F1 | Coronin 2A-dependent LXR transrepression pathway in macrophages |
| PMC3203685__F1 | Summary of the Proceedings from the 10th Annual Meeting of Molecularly Targeted Therapy in NSCLC |
| PMC3203691__F3 | CXCL10/IP-10 in Infectious Diseases Pathogenesis and Potential Therapeutic Implications |
| PMC3203699__F8 | TRAF3-mediated positive and negative regulation of IFN signaling |
| PMC3203793__F6 | Molecular modulation of peripheral myelination by the Sirt2/Par-3/aPKC pathway |
| PMC3203793__F1 | Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. |
| PMC3204078__F5 | SHP-1 activation and modulation on ghrelin signaling to Akt |
| PMC3204314__F7 | Signalling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis |
| PMC3204345__F1 | Multiple Smad phosphoisoforms exist |
| PMC3204462__F1 | TRAIL signaling pathway and regulatory proteins |
| PMC3205057__F6 | Influence of miR-300 on apoptosis pathway |
| PMC3205057__F8 | Effect of miRNAs on cell cycle, proliferation, and differentiation |
| PMC3205232__F1 | A brief survey of mRNA surveillance |
| PMC3205276__F1 | Biosynthetic pathway of sphingolipids consisting of free long chain bases (top row), which are N-acylated by several CerS enzymes to form dihydroceramides (upper row of octagons) |
| PMC3205325__F2 | Canonical TGFB signaling; Smad-dependent pathway downstream of TGFB receptors |
| PMC3205612__F1 | Interplay between autophagy and intracellular pathogens |
| PMC3205681__F2 | Post-translational modifications (PTMs) of transcription factors |
| PMC3205804__F2 | From a physiological point of view, exfoliated epithelial cells resulting from nutritional induction or mild stress are in anoikis by activating a survival mechanism partly using the molecular paths of macroautophagy |
| PMC3205852__F10 | Schematic illustrating the potential role of integrin B3 (ITGB3) in ROS-induced migration and invasion of colorectal cancer cells |
| PMC3206016__F9 | Putting into Practice Domain-Linear Motif Interaction Predictions for Exploration of Protein Networks |
| PMC3206070__F2 | Temporal Order of Genetic and Pathway Alterations in Tumorigenesis |
| PMC3206090__F2 | Convergent pathogenic pathways in Alzheimer's and Huntington disease: Shared targets for drug development |
| PMC3206090__F5 | Convergent pathogenic pathways in Alzheimer's and Huntington disease: Shared targets for drug development |
| PMC3206202__F9 | Expression Profiling Reveals Differential Gene Induction Underlying Specific and Non-Specific Memory for Pheromones in Mice |
| PMC3206202__F10 | Expression Profiling Reveals Differential Gene Induction Underlying Specific and Non-Specific Memory for Pheromones in Mice |
| PMC3206266__F3 | Androgen biosynthesis in the prostate |
| PMC3206369__F1 | Primary phosphatases function as tumor suppressors and their signaling pathways |
| PMC3206384__F1 | Schematic diagram depicting the possible pathways in which NO modulates collagen type I gene expression to affect fibrosis |
| PMC3207123__F1 | A view of CD133 expression as it relates to variety of normal tissue and cancer stem cells |
| PMC3207219__F1 | ROCK signaling pathway with focus on survival and regeneration |
| PMC3207473__F7 | Model: TTP transition from "hypo- to hypermodified" determines its functional switch |
| PMC3208056__F4 | Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/Beta-catenin/cyclin D1 signaling pathway in rats |
| PMC3208628__F5 | Integrated Transcriptome and Binding Sites Analysis Implicates E2F in the Regulation of Self-Renewal in Human Pluripotent Stem Cells |
| PMC3208682__F1 | Expression patterns of the TLR signaling pathway in CLL |
| PMC3208757__F6 | Ablation of p21-Activated Kinase-1 in Mice Promotes Isoproterenol-Induced Cardiac Hypertrophy in Association with Activation of Erk1/2 and Inhibition of Protein Phosphatase 2A |
| PMC3209136__F2 | Biosynthetic pathway for UA and flocculosin |
| PMC3209254__F9 | The multiple mechanisms by which Sox2 regulates the osteoblast lineage |
| PMC3209293__F6 | IA30-infected pigs fail to induce immune response genes associated with pattern recognition of viruses and cytokine and immune cell responses in the lung |
| PMC3209350__F1 | Synthesis, utilization, and regeneration of glutathione and regulation of mTORC1 activity |
| PMC3209670__F3 | mTOR signaling pathway affected by pollen feeding or varroa parasitism |
| PMC3209802__F1 | Assembly of checkpoint and repair machineries at DNA damage sites |
| PMC3210079__F8 | Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells |
| PMC3210466__F1 | MTOR signaling pathways |
| PMC3210925__F5a | Mapping photoautotrophic metabolism with isotopically nonstationary 13C flux analysis |
| PMC3212439__F5 | Immunoproteasomes Regulate Lps-Induced Trif/Tram Signaling Pathway in Murine Macrophages |
| PMC3213081__F1 | The P2X7 Receptor in Infectious Diseases |
| PMC3213160__F3 | Capture of MicroRNA-Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling |
| PMC3213224__F3 | Possible mechanism of reciprocal enhancement between innate and adaptive immunity, through NF-kB and STAT-1/IRF-1 pathway |
| PMC3213329__F3 | Ingenuity pathway analysis of phosphatidylinositol 3-kinase (PI3K) signaling pathway affected by angiotensin II |
| PMC3213398__F7 | Working Model for the Late-Acting Function of NFU1 in Mitochondrial Fe-S Protein BiogenesisThe findings of this work suggest a late-acting function of NFU1 in the pathway of Fe-S (red and yellow circles) protein maturation |
| PMC3213687__F2 | Appearance frequencies of genes in the mTOR signaling pathway |
| PMC3213765__F12 | Schematic of the sonic hedgehog signaling pathway |
| PMC3213765__F13 | The sonic hedgehog signaling pathway in the primary cilium |
| PMC3213765__F20 | Shh and BMP signaling |
| PMC3213966__F3 | Regulation of cardiac hypertrophy by AKAP complexes |
| PMC3214144__F1 | HCMV promotes GBM pathogenesis |
| PMC3214149__F3 | Schematic overview of CagL and CagA-mediated signal transduction pathways involved in H |
| PMC3214273__F1 | Pathogenic microbes and community service through manipulation of innate immunity |
| PMC321431__F10 | Cascade of transcription factors that induce stress gene expression in response to eIF2A phosphorylation |
| PMC321455__F9 | A model depicting the relationship between the p19Arf-p53 tumor suppressor pathway and the Rho GTPase signaling module in the regulation of cell proliferation and transformation |
| PMC3215281__F7 | Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease |
| PMC3215729__F1 | Rv2607 from Mycobacterium tuberculosis Is a Pyridoxine 5'-Phosphate Oxidase with Unusual Substrate Specificity |
| PMC3215775__F1 | Molecular mechanisms through the Epidermal Growth Factor Receptor pathway |
| PMC3215886__F2 | The "inhibitory" pathway of WNK4 |
| PMC3215943__F3 | MOLECULAR MECHANISMS OF FEAR LEARNING AND MEMORY |
| PMC3215943__F4 | MOLECULAR MECHANISMS OF FEAR LEARNING AND MEMORY |
| PMC321618__F7 | Statins and bacterial infection: model illustrating the effects of statins on S. enterica serovar Typhimurium infection |
| PMC3216277__F1 | Within the intestinal lumen, the micellar solubilization of sterols facilitates movement through the diffusion barrier overlying the surface of the absorptive cells |
| PMC3216277__F5 | Pathways underlying the absorption of cholesterol from the intestinal lumen and its delivery to the liver |
| PMC3216306__F1 | Downregulation of macrophages signalling by Leishmania infection |
| PMC3216677__F1 | Proposed estrogen receptor (ER)-activated signaling pathways involved in vasodilation |
| PMC3216694__F1 | Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors |
| PMC3216974__F7 | S6K1 and 4E-BP1 Are Independent Regulated and Control Cellular Growth in Bladder Cancer |
| PMC3217183__F5 | Signaling components of the RAS/MAPK pathway found to harbor activating mutations in various types of nevi and melanoma |
| PMC3217196__F1 | MicroRNAs in Mutagenesis, Genomic Instability and DNA Repair |
| PMC3217209__F1 | Insulin Resistance, Hyperglycemia, and Atherosclerosis |
| PMC321741__F1 | Signaling pathways for TLR-3 and TLR-4 |
| PMC3218055__F3 | Proteomic Signatures of Human Oral Epithelial Cells in HIV-Infected Subjects |
| PMC3218540__F2 | Folate metabolic pathway |
| PMC3218720__F2 | Receptors that sense danger signals released from neighboring injured retinal pigment epithelial (RPE) cells |
| PMC3218743__F2 | Inflammation in the gouty joint |
| PMC3218875__F2 | Noncanonical NFKB signalling |
| PMC3218884__F4 | Signalling network of proteins identified as major targets of autoantibodies in patients with unidentified ANA |
| PMC3218904__F1 | Network pathway analysis of up-regulated genes in the gene category immune response |
| PMC3218904__F2 | Network pathway analysis of down-regulated genes in the gene category mitotic cell cycle |
| PMC3218922__F6 | Pathway generated by ingenuity pathway analysis with proteins identified as specific target antigens |
| PMC3218933__F2 | Cross-talk among embryonic signaling pathways and experimental inhibitors |
| PMC3218933__F3 | Embryonic pathway signaling leads to induction of epithelial-to-mesenchymal transition |
| PMC3219052__F1 | SRC-3ÃŽâ€4 isoform acts a signaling adaptor for EGF-dependent cancer cell migration and invasion |
| PMC3219092__F3 | Nox regulation of the PI3K/AKT pathway |
| PMC3219211__F1 | Small-molecule inhibitors in the ubiquitin-proteasome system (UPS) |
| PMC3219404__F1 | Putative involvement of the receptor for advanced glycation endproducts (RAGE) during infection |
| PMC3219632__F11 | Suppressor of Cytokine Signalling-6 Promotes Neurite Outgrowth via JAK2/STAT5-Mediated Signalling Pathway, Involving Negative Feedback Inhibition |
| PMC3219972__F3 | Effect of carbon exchange and reversibility constraints |
| PMC3220493__F6 | Schematic model in which FGF2 stimulation of osteoblast differentiation is partially through modulation of the Wnt/Beta-catenin pathway |
| PMC3221387__F1 | Impact of miR-215 on cell proliferation, cell cycle, chemoresistance, and EMT |
| PMC3221598__F3 | Protease Regulation: The Yin and Yang of neural development and disease |
| PMC3221684__F8 | Insulin Receptor-Mediated Signaling via Phospholipase CG Regulates Growth and Differentiation in Drosophila |
| PMC3221730__F2 | 14-3-3 negatively regulates Hippo pathway signaling |
| PMC3221733__F3 | Drosophila melanogaster as a model system for human brain cancers |
| PMC3221743__F5 | Working model describing how in HIV+ macrophages constitutively activated PI3K elicits blunting of lipid A-induced increases in TNFA release through sustained mTOR activation |
| PMC3221843__F2 | Novel functions of MICAL proteins |
| PMC3222593__F2 | Pathway Studio® (Ariadne Genomics) was used to identify known relationships among human homologues of the genes identified as differentially regulated by ANOVA |
| PMC3222852__F1 | GSK3 plays pivotal roles in the establishment and maintenance of neuronal polarization |
| PMC3222852__F2 | GSK3 is a key regulator of axon growth and branching |
| PMC3223033__F6 | Schematic illustration of the main metabolic pathways based on the proteins identified in the citrus pulp chromoplasts |
| PMC3223252__F7 | A refined model shows MEHP-decreased TIMP2 expression in Sertoli cells is mediated by the inactivation of CEBPA and the activation of MYC and is dependent upon the FSH-stimulated cAMP signaling pathway |
| PMC3223826__F5 | JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors |
| PMC3224136__F7 | Schematic pathway showing a possible role for STC2 in affecting the PERK signalling pathway |
| PMC3224200__F1 | Contribution of chemoattractant GPCRs to glioma stem-like cell mediated tumorigenesis, invasion and angiogenesis express various GPCRs |
| PMC3224393__F1 | Reaction scheme for EGFR signal transduction pathway in H1299 cells |
| PMC3224437__F4 | Fatty acid biosynthesis model and pathway distance calculation method |
| PMC3224542__F1 | Genes related with the tau protein phosphatase-2A (PP2A) pathway |
| PMC3224806__F1 | Deciphering the role of Th17 cells in human disease |
| PMC3225017__F2 | c-MET signaling adaptors and mediators |
| PMC3225017__F3 | c-MET transactivation |
| PMC3225020__F1 | The c-MET (mesenchymal-epithelial transition factor) dependent signaling pathway |
| PMC3225028__F2 | WT1/EGR1-mediated Control of STIM1 Expression and Function in Cancer Cells |
| PMC3225503__F6 | Pathway model based on vision related TMT-associated gene expression changes indicating a possible mechanism for TMT elicited neurobehavioral changes |
| PMC3225656__F1 | Model of the glucose sensing network of S |
| PMC3225910__F1 | Signaling network connecting Rheb and AMPK |
| PMC3225948__F7 | Three arms of the unfolded protein response stress-responsive signaling pathway |
| PMC3226036__F5 | A schematic representation of the two classical apoptotic pathways in mammalian cells |
| PMC3226194__F7 | An integrated pathway model involving FOXA1 in breast cancer |
| PMC3226315__F1 | Recent focus in JMML has concentrated on using the information gained from knowledge of these molecular defects in order to design targeted drug therapy |
| PMC3226388__F3 | Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway |
| PMC3226689__F7 | Hole-in-One Mutant Phenotypes Link EGFR/ERK Signaling to Epithelial Tissue Repair in Drosophila |
| PMC3227097__F6 | Network of core pathways that mediate commitment of cells to the division cycle |
| PMC3227454__F2 | Epidermal growth factor and aging: A signaling molecule reveals a new eye opening function |
| PMC3227570__F9 | Divergent BMP signaling pathways controlling transcriptional and cytoskeletal responses |
| PMC3227667__F3 | Genetic Signature of Spina Bifida Risk from Pathway-Informed Comprehensive Gene-Variant Analysis |
| PMC3227781__F2 | Genomic and nongenomic vascular effects of estrogen |
| PMC3227927__F1 | Signaling pathways and effects of EGFR |
| PMC3227936__F1 | EGFR signaling pathway |
| PMC3227962__F5 | Targets for intervention in the TGFB1 pathway (partial list) [, , ] |
| PMC3228010__F1 | Signaling pathways of sunitinib and sorafenib cardiotoxicity |
| PMC3228119__F1 | PI3K/AKT/mTOR signaling network regulates cell survival, proliferation, migration, metabolism, and apoptosis, integrating the growth factor signaling pathway, nutrient status, and other oncogenic pathways |
| PMC3228122__F1 | Proposed unified model of the pathophysiology of CD representing the different known and suggested mechanisms involved in that disease |
| PMC3228218__F1 | HCG/MET signaling pathway [] |
| PMC3228224__F1 | Pathways involved in mTOR signaling.Abbreviations: mTOR, mammalian target of rapamycin; PI3K, phosphoinositide 3-kinase; TSC, tuberous sclerosis.Adapted from: Kopelovich L, Fay JR, Sigman CC, Crowell JA |
| PMC3228878__F1 | Several types of TG2-containing adhesive / signaling complexes present on the cell surface |
| PMC3228910__F2 | Expanded representation of the KEGG pathway "colorectal cancer" |
| PMC3228973__F4 | Proposed signal transduction pathways in nodose ganglia following receptor activation with leptin and cholecystokinin-8 (CCK-8) |
| PMC3229036__F2 | Subversion of the actin cytoskeleton during viral infection |
| PMC3229193__F2 | Model for transcriptional-3'-end processing alternatives during the DNA damage response (DDR) |
| PMC3229968__F1 | Deciphering the role of Nuclear FactorKB in cellular senescence |
| PMC3229968__F2 | Deciphering the role of Nuclear FactorKB in cellular senescence |
| PMC3229968__F3 | Deciphering the role of Nuclear FactorKB in cellular senescence |
| PMC3229969__F2 | Roles of FGF signaling in stem cell self-renewal, senescence and aging |
| PMC3230271__F2 | NK cells: immune cross-talk and therapeutic implications |
| PMC3230300__F2 | Mucins in the Pathogenesis of Breast Cancer: Implications in Diagnosis, Prognosis and Therapy |
| PMC3230307__F1 | Autophagy regulation |
| PMC3230308__F1 | Autophagy pathway and relationship to mTOR signaling |
| PMC3230512__F1 | Model showing the various molecular components associated with the store-operated calcium entry pathway |
| PMC3230686__F3 | Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27 |
| PMC3230808__F7 | Regulation of CYP1A1 by capsaicin in Hepa-1c1c7 cells |
| PMC3231924__F1 | Simplified scheme for TLR signaling in enterocytes |
| PMC3231999__F1 | Immune evasion strategies of Porphyromonas gingivalis |
| PMC3232381__F1 | Tumour necrosis factor receptor 1 (TNFR1) and its signalling pathways |
| PMC3233056__F7 | Different expressed proteins indicated in glycolysis, TCA cycle, pentose phosphate pathway, nucleotide metabolism, amino acid metabolism, and cell wall development |
| PMC3233269__F1 | PA can be generated de novo,, by sequential enzyme-catalyzed acylations of glycerol-3-phosphate, or in response to cell signaling pathways () |
| PMC3233269__F9 | G protein-coupled receptors (GPCR) trigger dissociation of GA and GBG heterotrimeric G proteins upon agonist stimulation |
| PMC3233287__F2 | Illustration of main mechanisms of trastuzumab resistance (in red) and targeted agents to circumvent resistance (in blue) |
| PMC3233485__F1 | E2F1 can either promote either DNA repair or apoptosis in response to DNA damage, which should exert opposing effects on cell survival |
| PMC3233530__F2 | Insertional mutagenesis identifies multiple networks of co-operating genes driving intestinal tumorigenesis |
| PMC3233564__F3 | Mammalian MAPK signaling pathways |
| PMC3233625__F3 | Pleiotropic functions of EAPII/TTRAP/TDP2. |
| PMC3233626__F5 | NIRF interaction network |
| PMC3233666__F1 | Adaptation of endothelial cells to inflammatory stimuli and hypoxia |
| PMC3234195__F1 | Petroleum diesel, biodiesel, and ethanol |
| PMC3234240__F2 | Radiation-Induced Signaling Results in Mitochondrial Impairment in Mouse Heart at 4 Weeks after Exposure to X-Rays |
| PMC3234268__F5 | Genome Characterization of the Oleaginous Fungus Mortierella alpina |
| PMC3234318__F1 | OB inhibition by MM cells |
| PMC3234330__F1 | TGFB signaling pathway |
| PMC3234335__F1 | Hereditary Hemochromatosis and Transferrin Receptor 2 |
| PMC3234494__F3 | Cytosolic RNA sensors |
| PMC3234798__F9 | miR-26a pathway in the initiation of ASMC hypertrophy |
| PMC3235041__F1 | SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen |
| PMC3235480__F2 | RAF/MEK/ERK and the PI3K/AKT/mTOR signaling pathways are shown |
| PMC3235520__F1 | Proposed model of the type I interferon induction by HIV-1 and HIV-1-infected cells |
| PMC3235896__F2 | Transdifferentiation of bone-marrow-derived mesenchymal stem cells (MSCs) into the multiple skin component cells |
| PMC3235907__F1 | Clopidogrel activation and platelet aggregation pathways |
| PMC3236061__F5 | Cooperation of the genes in the DNA repair cluster |
| PMC3236209__F6 | Transcriptome Analysis of H2O2-Treated Wheat Seedlings Reveals a H2O2-Responsive Fatty Acid Desaturase Gene Participating in Powdery Mildew Resistance |
| PMC3236216__F5 | Distinct Peripheral Blood RNA Responses to Salmonella in Pigs Differing in Salmonella Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways |
| PMC3236216__F8 | Distinct Peripheral Blood RNA Responses to Salmonella in Pigs Differing in Salmonella Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways |
| PMC3236328__F1 | Main NFKB-activating pathways |
| PMC3236328__F2 | The differentiation hierarchy within the mammary epithelium and potential relationships with breast cancer subtypes |
| PMC3236456__F2 | Fungal cell wall pathogen-associated molecular patterns (PAMPs) and their host-pattern recognition receptors (PRRs) |
| PMC3236456__F3 | Hypothetical model for a molecular chitinase response to chitin-containing pathogens or particles |
| PMC3236512__F2 | Effect of FXR activation on triglyceride and cholesterol metabolism in the liver |
| PMC3236571__F7 | Resistance mechanisms in the TRAIL signaling pathway |
| PMC3236573__F3 | Ovarian cancer ascites-mediated protection from TRAIL-induced apoptosis |
| PMC3236823__F2 | Evolution of the mTOR pathway |
| PMC3237253__F3 | Adhesion of sickle red blood cells to the endothelium and cell activation |
| PMC3237851__F8 | Proposed signaling pathway for the role of SGK1 in Ang II-mediated cell survival |
| PMC3237908__F4 | Schematic diagram shows the possible effect of xanthones on the apoptosis pathways |
| PMC3238080__F2 | Regulation of intracellular signaling by antiepileptics and modulators of glutamate, acetylcholine, and melatonin systems |
| PMC3238182__F1 | Involvement of miR-221/222 as downstream effectors of the EGFR-RAS-RAF-MEK pathway in progression of metastatic transformation of breast cancer tumors |
| PMC3238295__F5 | Bridged pairs and shared edges between 2ROs in the apoptosis pathway |
| PMC3238353__F1 | ER stress and activation of the UPR signalling pathways |
| PMC3238353__F2 | Crosstalk between UPR signalling pathways and lipogenesis |
| PMC3238469__F2 | Gene expression changes in cell cycle pathways |
| PMC3239234__F3 | Various signaling pathways modulated by the primary cilium |
| PMC3239343__F2 | Intracellular signalling during inflammation-induced osteoclastogenesis |
| PMC3240145__F2 | Intrinsic and extrinsic pathways of apoptosis |
| PMC3240659__F3 | Repeated Small Perturbation Approach Reveals Transcriptomic Steady States |
| PMC3240668__F6 | Fibronectin - c-Myc network |
| PMC3240703__F2 | Glycosylated Synaptomatrix Regulation of Trans-Synaptic Signaling |
| PMC3240715__F3 | Molecular mechanisms of FGFR3 signaling in cartilage |
| PMC3240717__F9 | Pro-inflammatory Cytokine/Chemokine Production and Breast Tumor Invasion |
| PMC3241001__F1 | Pharmacologic Induction of CD8+ T Cell Memory: Better Living Through Chemistry |
| PMC3241422__F10 | Control of Rho1 activity through the cell cycle |
| PMC3241604__F7 | Proposed MAPK pathways and their inhibitors involved in EVT dysfunction during an inflammatory state |
| PMC3241690__F7 | Crosstalk between Nuclear Factor I-C and Transforming Growth FactorB1 Signaling Regulates Odontoblast Differentiation and Homeostasis |
| PMC3241725__F2 | Bacterial manipulation of mitochondrial cell death pathways |
| PMC3241725__F3 | Bacterial manipulation of host pro-survival pathway |
| PMC3241928__F8 | Beta-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas |
| PMC3241960__F5 | Sarcolemmal actin assembly and nuclear signaling |
| PMC3241972__F1 | TOR in the immune system |
| PMC3242363__F5 | The mechanism of late PC |
| PMC3242418__F1 | HER 2: Biology, Detection, and Clinical Implications |
| PMC3242749__F4 | Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice |
| PMC3242881__F6a | Src REGULATES SPHINGOSINE-1-PHOSPHATE MEDIATED SMOOTH MUSCLE CELL MIGRATION |
| PMC3243033__F1 | Regulation of epidermal homeostasis by PCP signaling |
| PMC3243049__F3 | The autophagy pathway is affected at different steps in the various types of dementias |
| PMC3243079__F2 | Non-genomic ERA pathway |
| PMC3243091__F2 | Molecular control of palatal shelf growth and patterning |
| PMC3243113__F10 | MULTIPLE WAYS TO DIE: DELINEATION OF THE UNFOLDED PROTEIN RESPONSE AND APOPTOSIS INDUCED BY SURFACTANT PROTEIN C BRICHOS MUTANTS |
| PMC3243301__F2 | Basic pathway controlling the G1/S transition |
| PMC3243339__F8 | Depiction of how D1 and c-Myc proteins regulate CDDP-induced cell death, with arrow indicating induction and hyphen (-|) indicating inhibition |
| PMC3243341__F3 | Conversion of major constituents in the stem cuticular wax biosynthetic pathway |
| PMC3243350__F1 | Biosynthetic pathway of oxylipins in Arabidopsis |
| PMC3243355__F3 | Sugar Sensing and Signaling |
| PMC3243479__F3 | Fatty acid Beta-oxidation, TG synthesis, and phospholipid biosynthesis pathways |
| PMC3243745__F6 | Metabolic pathways illustrating TCDD-elicited changes in the mouse (A) and rat (B) |
| PMC3243790__F1 | Regulation of ABCA1 Functions by Signaling Pathways |
| PMC3243812__F8 | Beta2-adrenergic receptor engagement on a B cell that will make IgE uses a unique signaling pathway to increase the level of IgE produced |
| PMC3244200__F4 | Epithelial-mesenchymal transition (EMT)-related pathways |
| PMC3244904__F4 | Eukaryotic Phospholipid Synthesis and Editing.G3P produced by GPDH is converted to PA by sequential acylation reactions regulated by GPAT and LPAAT |
| PMC3245020__F3 | Disease/drug mapping is the process to map all known disease genes (pink) and all known drug targets (light blue) against all KEGG pathway maps |
| PMC3245021__F3 | Reformatted modeling of the BioCarta 'apoptotic signaling in response to DNA damage' pathway |
| PMC3245119__F2 | Non-canonical Wnt-signaling pathway |
| PMC3245201__F1 | Topography and signaling pathways triggered by selectin ligands in neutrophils |
| PMC3245324__F2 | Ischemic preconditioning (IPC): signaling pathways and targets |
| PMC3245506__F1 | Network of differentially expressed genes in HMGA1 transgenics at 2 months (nonparametric CAM approach) |
| PMC3245506__F2 | Network of differentially expressed genes in HMGA1 transgenics at 2 months (parametric approach) |
| PMC3245506__F3 | Network of differentially expressed genes in transgenics at 2 months (parametric and nonparametric approaches) |
| PMC3245506__F4 | Network of differentially expressed genes in HMGA1 transgenics at 12 months (nonparametric approach) |
| PMC3245506__F5 | Network of differentially expressed genes in HMGA1 transgenics at 12 months (parametric approach) |
| PMC3245506__F6 | Network of differentially expressed genes in transgenics at 12 months (parametric and nonparametric approaches) |
| PMC3245550__F2 | Arf Family G Proteins and their regulators: roles in membrane transport, development and disease |
| PMC3245622__F1 | PI3K/Akt signaling pathway is involved in several human cancers |
| PMC3245719__F1 | Bioenergetic regulation of cellular physiology and gene expression |
| PMC3245760__F2 | Cannonical pro-fibrotic TGFB signaling is initiated by the binding of active TGFB to TGFB receptors |
| PMC3246074__F2 | Vitamin A and immune regulation: Role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance |
| PMC3246295__F2 | Gab2 interactions with binding partners |
| PMC3246337__F9 | A Small-Molecule Screen Identifies l-Kynurenine as a Competitive Inhibitor of TAA1/TAR Activity in Ethylene-Directed Auxin Biosynthesis and Root Growth in Arabidopsis |
| PMC3246369__F2 | Small RNAs in transcriptional gene silencing and genome defence |
| PMC3246422__F10 | PP-associated modulation of inflammatory chemokine production and repair-related processes in keratinocytes through EGFR system |
| PMC3246665__F6 | Diagram of signalling pathways indicating the possible mechanism by which sildenafil reverses the memory deficits in aged transgenic Tg2576 mice |
| PMC3246677__F2 | Regulation of viperin expression |
| PMC3246786__F2 | The role of CYLD in canonical and noncanonical NFKB pathway |
| PMC3247287__F8 | Profiling Insulin Like Factor 3 (INSL3) Signaling in Human Osteoblasts |
| PMC3247643__F6 | Overlay of significant canonical pathway and the connectivity in the molecular mechanism of cancer, with the eight genes in IPA canonical pathway and with the genes in Network (I) that differentially altered in PCB exposure |
| PMC3247754__F3 | Simplified view of the glucose sensing mechanisms in S |
| PMC3247963__F7 | Model illustrating that early and late ISGs induction is regulated by multiple STAT1 posttranslational modifications |
| PMC3247990__F8 | Post-induction repression of IFNB expression by YY1 in TLR3 signaling pathway |
| PMC3248020__F9 | Schematic representation of S100A7-mediated signaling that inhibits proliferation and motility in ERA+ breast cancer |
| PMC3248149__F3 | Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence |
| PMC3248170__F1 | Therapeutic Strategies to Overcome Acquired Resistance to BRAF or MEK Inhibitors in BRAF Mutant Cancers |
| PMC3248179__F2 | Evi1 forms a bridge between the epigenetic machinery and signaling pathways |
| PMC3248184__F1 | YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention |
| PMC3248191__F7 | Network Modeling of MDM2 Inhibitor-Oxaliplatin Combination Reveals Biological Synergy in wt-p53 solid tumors |
| PMC3248194__F3 | RIP Kinase-Mediated Necrosis as an Alternative Mechanism of Photoreceptor Death |
| PMC3248195__F1 | Elevated PI3K signaling drives multiple Breast Cancer subtypes |
| PMC3248218__F3 | NUAK2: an emerging acral melanoma oncogene |
| PMC3248275__F7 | Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice |
| PMC3248767__F2 | Bevacizumab Treatment for Advanced Breast Cancer |
| PMC3248866__F2 | HPV 16 E5 enhances growth factor signalling pathways |
| PMC3248879__F1 | Network images of FTO and candidates genes |
| PMC3248879__F4 | In silico analysis and gene expression studies suggests functional coupling between FTO and the BDNF/NTRK2-signalling pathway |
| PMC3249073__F1 | PtdEtn synthesis pathways in Plasmodium and yeast |
| PMC3249369__F4 | Three MAPK pathways in yeast share common components and also contain pathway-specific factors |
| PMC3249400__F1 | AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism |
| PMC3249400__F2 | AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism |
| PMC3249400__F4 | AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism |
| PMC3249418__F3 | Migration of marginal zone precursor B cells regulated by type I interferon (IFN) and IL-17 |
| PMC3249608__F2 | RA-dependent non-transcriptional involvement in neurite outgrowth |
| PMC3250080__F1 | CR-associated signaling and some of its key players |
| PMC3250173__F7 | TLR3/TLR4-mediated signaling pathways |
| PMC3250228__F3 | FOLATE-ALCOHOL AND CANCER PATHWAY HYPOTHESES |
| PMC3250521__F4 | Inhibition of isoprenoid biosynthetic pathway by ATST [modified from Holstein et al |
| PMC3250525__F3 | Visualization of the quantity of genes differentially regulated by Gamma-tocotrienol (GT3) and Alpha-tocopherol (aTOC) using the KEGG cell cycle pathway |
| PMC3250614__F2 | TGFB signal transduction pathway and targets for therapeutic intervention |
| PMC3251006__F5 | ECM-receptor interaction and focal adhesion pathway |
| PMC3251532__F5 | The lymphocte-specific gene (A) or urine peptide (B) markers |
| PMC3251560__F7 | Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes |
| PMC3251560__F8 | Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes |
| PMC3251560__F9 | Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes |
| PMC3251651__F4 | Novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy |
| PMC3251736__F2 | Ingenuity pathway analysis (IPA) of the EGFR ablation signature with oncogenic (A) and wildtype Ras (B) |
| PMC3251776__F6 | Proposed similarities and differences in the maps of E |
| PMC3251842__F2 | TGFB response pathway |
| PMC3251883__F4 | Proposed mechanism for VEGFA165 induced tumour growth |
| PMC3252343__F4 | Expression Signature of IFN/STAT1 Signaling Genes Predicts Poor Survival Outcome in Glioblastoma Multiforme in a Subtype-Specific Manner |
| PMC3252731__F1 | TLR4 signaling pathway is highly regulated |
| PMC3252742__F4 | Apoptotic pathway in cardiac myocytes |
| PMC3252833__F1 | Fas-induced apoptotic signalling pathway |
| PMC3252833__F3 | Sensitisation of type 2 cancer cells towards DR-induced killing by synthetic IAP antagonists |
| PMC3253010__F3 | A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. |
| PMC3253327__F1 | Acute and Chronic Regulation of Aldosterone Production |
| PMC3253327__F2 | Acute and Chronic Regulation of Aldosterone Production |
| PMC3253558__F1 | Conserved Herpesvirus Kinases Target the DNA Damage Response Pathway and TIP60 Histone Acetyltransferase to Promote Virus Replication |
| PMC3253704__F1 | Prominent signaling pathways involved with PDAC tumoral compartment and stromal compartment crosstalk |
| PMC3253886__F4 | IRF signaling pathway that was generated from pathway analysis of proteins with significant fold changes across both studies |
| PMC3253915__F2 | Innovative Therapy for Classic Galactosemia - Tale of Two HTS |
| PMC3254042__F7 | Signaling pathways involved in synaptic plasticity and neuroglia functions with associated molecules and cellular tasks (analysis based on Ingenuity IPA software) |
| PMC3254618__F3 | Identification of Gene Networks and Pathways Associated with Guillain-Barré Syndrome |
| PMC3254631__F5 | MiRNA Expression by Dietary Polyphenols in apoE Deficient Mice: A New Mechanism of the Action of Polyphenols |
| PMC3254670__F1 | Metabolic connections during apoptotic cell engulfment |
| PMC3255271__F1 | Study schema |
| PMC3255316__F1 | Factors affecting the viability of dopamine neurons |
| PMC3255319__F1 | Oncogenic and tumor suppressor control of metabolism |
| PMC3255710__F2 | Fine adjustment of autophagy by the AMPK-mTORC1-Ulk1/2 kinase network |
| PMC3255783__F7 | Model depicting the potential roles of Hrq1 in NER-based lesion processing |
| PMC3255869__F1 | TLR4 signaling pathway |
| PMC3256223__F1 | Modeling of miRNA and Drug Action in the EGFR Signaling Pathway |
| PMC3256462__F1 | Basic signaling pathways and relevant targets together with their inhibitors associated with endocrine resistance Estrogen receptor alpha (ER) and the growth factors (esp |
| PMC3256849__F6 | A model for Kv1.3-mediated signaling pathway in human T effector memory cell differentiation |
| PMC3256879__F8 | A hypothetical diagram of the involvement of ATF6 in BMP2-induced osteoblast differentiation |
| PMC3256998__F6 | Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells. |
| PMC3257109__F3 | BMP signaling in motor neurons |
| PMC3257556__F2 | Known components of the PCP signalling pathway and related cellular functions |
| PMC3257565__F2 | HSC cell cycle entry is regulated by a complex network of cell-intrinsic and cell-extrinsic factors |
| PMC3257580__F1 | Kruppel-like factors in lymphocyte biology |
| PMC3257753__F1 | TWEAK-Fn14 signaling system |
| PMC3258214__F1 | Bcl-3 signaling cascade |
| PMC3258305__F2 | The Long History of Iron in the Universe and in Health and Disease |
| PMC3258432__F6 | Factors shown to promote or inhibit the vascular normalization phenotype in tumors |
| PMC3258560__F1 | Signal transduction by TGFB family members |
| PMC3258586__F1 | PI3K pathway activated by EGF-stimulated EGFR or by the constitutively activated EGFRvIII |
| PMC3259192__F2 | Sphingolipid Signaling and Hematopoietic Malignancies: To the Rheostat and Beyond |
| PMC3259218__F1 | Gemcitabine metabolic pathway genetic polymorphisms and response in non-small cell lung cancer patients |
| PMC3259275__F2 | ATM interaction with metabolic signaling pathways |
| PMC3259514__F1 | Different signaling pathways leading to the induction of virus stress-inducible genes (VSIGs) and interferon-stimulated genes (ISGs) |
| PMC3259815__F8 | Signaling through PAK in the hyperosmotic response pathway |
| PMC3260001__F1 | Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells |
| PMC3260150__F2 | Identification of a Potential Ovarian Cancer Stem Cell Gene Expression Profile from Advanced Stage Papillary Serous Ovarian Cancer |
| PMC3260274__F5 | Tumour Suppressive Function and Modulation of Programmed Cell Death 4 (PDCD4) in Ovarian Cancer |
| PMC3260452__F2 | Simplified model of the leptin signaling pathway |
| PMC3260518__F1 | Invisible hand: regulation of RHO GTPases by RHOGDIs |
| PMC3260548__F1 | The signaling cascade in response to the release of dsRNA from LRV particles, production of IFNB and secretion of proinflammatory cytokines and chemokines |
| PMC3260552__F4 | Melanoma signaling networks, progression, and influences by the BCL-2 family |
| PMC3260807__F1 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health |
| PMC3260807__F2 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health |
| PMC3260807__F4 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health |
| PMC3260814__F1 | Personalizing Therapy with Targeted Agents in Non-Small Cell Lung Cancer |
| PMC3260854__F6 | FosB-mediated regulation of ECM genes by mechanical signaling in bladder smooth muscle |
| PMC3260860__F6 | Scheme of the EGR-1/GGPPS/ERK 1/2 pathway |
| PMC3260921__F2 | Integrin signalling pathway |
| PMC3261278__F1 | Synaptic translation and signaling pathways modulated by FMRP (a) and dysregulation of these pathways in the absence or significant reduction of FMRP (b) |
| PMC3261278__F2 | Targeted treatments for fragile X syndrome. |
| PMC3261582__F1 | JNK signaling enhances the compensatory proliferation of the neighboring cells, stem cells or cancer stem cells (CSCs) |
| PMC3261702__F4 | Structural coverage of the core vision pathway and its links to other functional modules |
| PMC3261822__F3 | IPA-based pathway analysis of differential expressed genes |
| PMC3261843__F6 | Biochemical pathways and enzymes involved in carbon and nitrogen metabolism in Cyanothece ATCC51142 |
| PMC3262099__F8 | The host cell EGF signaling pathway and proteins downstream of the EGF receptor that are activated in response to C |
| PMC3262193__F3 | Signaling pathways and proteins that increase or decrease STAT5 signaling in normal mammary epithelial cells |
| PMC3262331__F2 | Schematic signaling pathway mediated by the L-CBM complex in T and B lymphocytes.Notes: The L-CBM complex acts in the canonical NFKB (p65/p50, cRel/p50) activation pathway mediated by IKKB downstream of TCRs and BCRs |
| PMC3262331__F3 | Schematic signaling pathway mediated by the L-CBM complex in NK cells.Notes: The L-CBM complex acts in the canonical NFKB activation pathway through activating NK cell receptors (NKR) such as Ly49H, Ly49D, NK1.1, NKG2D, FcGRIII, etc |
| PMC3262546__F1 | The p14-p53-p21 and p16-Rb signaling pathways involved in fibroblast senescence |
| PMC3262611__F1 | Folic acid metabolism |
| PMC3262938__F2 | N-glycan biosynthetic pathways in eukaryotes and glycoengineering |
| PMC3262999__F1 | Interaction between Jak2/Stat5 signaling and the PI3K/Akt1 pathway in mammary epithelial cells |
| PMC3263309__F1 | Notch, Wnt, and Hedgehog signaling pathways regulate normal and stem cell fate |
| PMC3263503__F8 | Schematic depiction of crosstalk between Notch and HIF-1A |
| PMC3263550__F2 | Parkinson's disease pathway from the KEGG disease database |
| PMC3263561__F2 | Interaction between glia and neurons may lead to neuron damage and death |
| PMC3263596__F3 | TGFB pathway in NetSlim |
| PMC3263689__F2 | VHL complex targets HIF-1A and HIF-2A for ubiquitin-mediated degradation |
| PMC3263689__F5 | FLCN pathway |
| PMC3264379__F9 | Proposed model for regulation of HCV replication mediated by the Ras/Raf/MEK pathway |
| PMC3264680__F3 | Diagram of IGF/INSR/IGF1R signaling pathway |
| PMC3265021__F2 | Signal transduction events that link ER stress to inflammation |
| PMC3265067__F7 | Phospholipid biosynthetic pathways |
| PMC3265661__F1 | Putative role of the mTOR pathway in pathogenesis and epileptogenesis of focal cortical malformations |
| PMC3265777__F2 | Context-dependent regulation of Rho GTPase signaling |
| PMC3265821__F1 | Change in RAF isoform usage in response to a RAS mutation |
| PMC3265866__F7 | PGC-1Alpha- and AMPK-mediated regulation of IL1Rn expression in hepatocytes |
| PMC3266027__F1 | Activation of EGFR signaling in non-small-cell lung cancer (NSCLC) can occur via disruption of several different components at multiple levels of the pathway |
| PMC3266662__F3 | Correlations of genes in central carbon metabolism with SPPR |
| PMC3266773__F10 | CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression |
| PMC3266776__F2 | Understanding pRb: toward the necessary development of targeted treatments for retinoblastoma |
| PMC3266783__F2 | Basal cell carcinoma – molecular biology and potential new therapies |
| PMC3267157__F2 | P73 pathway and its regulators.A simplified view of the p73 pathway, of its regulators, and of the molecules that directly or indirectly can modulate its function |
| PMC3267662__F2 | IGF1R-IR/PI3K/Akt/mTOR pathway and its manipulation through diet |
| PMC3267701__F1 | Amyloid precursor protein (APP) processing pathway [-] |
| PMC3267732__F4 | Deeply Branching Thermophilic Bacterium with an Ancient Acetyl-CoA Pathway Dominates a Subsurface Ecosystem |
| PMC3267756__F9 | Coxiella burnetii Induces Apoptosis during Early Stage Infection via a Caspase-Independent Pathway in Human Monocytic THP-1 Cells |
| PMC3267942__F1 | UV lesions and their repair |
| PMC3268129__F1 | Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins |
| PMC3268188__F2 | Tumour suppressor p53 regulation and signalling |
| PMC3268389__F1 | Pathways and compartmentation of FA supply for TAG synthesis in plants |
| PMC3268503__F6 | The Chl branch.The first step of the Chl branch is the insertion of Mg2+ into Proto IX |
| PMC3268617__F2 | Dys-Syn-nNOS pathway and miRNAs coordinate the muscle differentiation program |
| PMC3268901__F1 | The PTEN/mTOR signaling pathway |
| PMC3268919__F8 | Schematic diagram showing the mechanism by which uPA/uPAR shRNA inhibits angiogenesis in glioblastoma cells and xenografts |
| PMC3268941__F1 | Canonical Wnt/Beta-catenin and non-canonical Wnt signaling pathways |
| PMC3269020__F1 | Pathways involved in aging |
| PMC3269020__F3 | Role of miRNAs in aging of mice |
| PMC3269021__F8 | Interaction of TOR pathway members for the regulation of phagocytosis |
| PMC3269300__F1 | DN Tregs employ multiple mechanisms to exert antigen-specific control over immune responses |
| PMC3269610__F1 | TGFB signaling and negative regulation in bone formation |
| PMC3269610__F2 | BMP signaling and negative regulation in bone formation |
| PMC3269658__F5 | Differentiation pathways of CSCs |
| PMC3269678__F2 | Signaling pathways leading to transcription factors activation in response to UV-radiation |
| PMC3269833__F6 | Potential regulatory mechanism of the identified gene switches for breast cancer |
| PMC3270028__F6 | Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling |
| PMC3270058__F9 | Endothelial adaptive response to moderate hypothermia (25°C/72 h) |
| PMC3270095__F4 | Regulatory network for PACAP-responsive genes |
| PMC3270101__F6 | Pathway map related to cisplatin-induced hepatotoxicity based on proteomic and genomic analysis |
| PMC3270146__F6 | A schematic presentation of the proposed TGFB and PTEN/PI3K/Akt signaling alteration that promotes HNSCC in mice |
| PMC3270265__F3 | Glucose metabolism in cancer cells |
| PMC3270265__F5 | Regulation of cell death by glucose metabolism |
| PMC3270444__F5 | Putative inhibitory pathway of LPS-activated inflammatory signaling responses by peptide K5 |
| PMC3270467__F1 | Putative galanin-mediated neuronal pro- and antinociceptive mechanisms in the dorsal horn of the spinal cord |
| PMC3270883__F1 | Exiting from uncharted territory: hepatitis C virus assembles in mouse cell lines |
| PMC3271045__F4 | Schematic summary of striatal gene expression changes in response to SNCA overexpression |
| PMC3271076__F8 | Novel YY1-miR-1 Regulatory Circuit in Skeletal Myogenesis Revealed by Genome-Wide Prediction of YY1-miRNA Network |
| PMC3271338__F3 | Defects and mutations resulting in mucocutaneous candidiasis |
| PMC3271643__F3 | Putative mechanism of estrogen action in rat Sertoli cells |
| PMC3271653__F1 | Testosterone signaling pathways |
| PMC3271661__F3 | Summary of Kit/Kitl signaling during spermatogenesis |
| PMC3271860__F3 | IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS |
| PMC3271860__F7 | THE ROLE OF IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS |
| PMC3272037__F10 | Diet and Energy-Sensing Inputs Affect TorC1-Mediated Axon Misrouting but Not TorC2-Directed Synapse Growth in a Drosophila Model of Tuberous Sclerosis |
| PMC3272624__F1 | Schematic depicting mTORC1 signaling in a NAC a medium spiny neuron with anterogradely transported BDNF being released from a VTA dopamine neuron terminal and glutamate released from a prefrontal cortex projection neuron |
| PMC3272682__F1 | Recognition of Pathogenic Nucleic Acids by Patterns Recognition Receptors and Signaling |
| PMC3272705__F1 | Subcellular itineraries of paradigmatic substrates of ubiquitin-dependent sorting pathways |
| PMC3272823__F3 | Involvement of the ERK pathway in the TGF-Beta-induced epithelial-mesenchymal transition |
| PMC3272847__F2 | E6-mediated survival signaling |
| PMC3272882__F3 | DRD2/GSK3B/DISC1 pathway modified from Beaulieu et al |
| PMC3273421__F2 | Myostatin and activin signaling in muscle |
| PMC3273665__F2 | SREBPs in the innate immune response |
| PMC3273847__F1 | Innate Immunity in the Host Defense Against intestinal Bacterial Pathogens |
| PMC3274456__F3 | Lipopolysaccharide (LPS)-dependent and nuclear factor (NF)KB-mediated activation of proinflammatory cytokines |
| PMC3274489__F1 | Overview of the mevalonate pathway |
| PMC3274818__F1 | Activation of an RTK induces dimerization and downstream phosphorylation of non-receptor tyrosine kinases |
| PMC3275089__F1 | Schematic overview of the ABeta-Cav1.2-ptau-autophagy pathway |
| PMC3275361__F3 | Signaling and cross talk of the PTH and Wnt signaling pathways in osteocytes |
| PMC3275500__F1 | The Ras-MAPK and TGFB pathways |
| PMC3275548__F3 | Liver from Campari tomato treatment |
| PMC3275780__AF2 | T cell activation |
| PMC3275810__F2 | Schematic display of the molecular interactions of apoptosis related molecules in dental apoptosis indicating the central position of the mitochondria pathway, which has been shown to be essential |
| PMC3276354__F1 | Canonical Wnt (Wnt/Beta-catenin) signaling pathway (adapted from Ref |
| PMC3276397__F1 | Effects of VitA in gut-associated lymphoid tissue |
| PMC3276472__F1 | Schematic in vivo biosynthetic pathway from 18:3n3 and 18:2n6 mediated by ELOVL4 and other ELOVL family proteins |
| PMC3276511__F2 | Mass Homozygotes Accumulation in the NCI-60 Cancer Cell Lines As Compared to HapMap Trios, and Relation to Fragile Site Location |
| PMC3276621__F2 | Pathways for the synthesis of glycerolipids and their subcellular localization |
| PMC3276974__F2 | Hypothetical model of LRRK2-mediated regulation of the miRNA pathway |
| PMC3277127__F5 | Curation of phosphoproteomic profiling and bioinformatics delineates distinct tyrosine kinase signaling pathways in an oncogene-specific manner |
| PMC3277529__F1 | Proposed model for TIMP-1-mediated suppression of the Wnt/Beta-catenin pathway via let-7f in human mesenchymal stem cells (hMSCs) |
| PMC3277712__F1 | Importance of cytokine signalling for CD4+ T-cell differentiation |
| PMC3277713__F1 | A schematic diagram of different components making up the interleukin-23 (IL-23) and IL-12 receptors and the common signal transduction and activator of transcription 4 (STAT4) activation pathway |
| PMC3277752__F2 | Browsing the ApoptoProteomics database |
| PMC3278439__F4 | Analysis of the Fibroblast Growth Factor System Reveals Alterations in a Mouse Model of Spinal Muscular Atrophy |
| PMC3278537__F2 | Signaling Pathways Underlying the Pathophysiology and Treatment of Depression: Novel Mechanisms for Rapid-Acting Agents |
| PMC3278592__F3 | The pleiotropic effects of erythropoietin in infection and inflammation. |
| PMC3278830__F3 | Functions related to hepatic cultures.Subgraphs of a hepatocyte response network induced by genes annotated with MSigDB gene sets |
| PMC3278831__F4 | Sample subnetwork formation |
| PMC3278889__F4 | TLR4 signaling to NFKB |
| PMC3278889__F5 | T-cell receptor (TCR) signaling to NFKB |
| PMC3278889__F6 | CD40 signaling to the alternative NFKB pathway |
| PMC3279601__F1 | The Immunologic Revolution: Photoimmunology |
| PMC3279615__F3 | Nucleotide excision repair (NER) pathway |
| PMC3279640__F1 | Bi-potential gonad development to either testis or ovary |
| PMC3279640__F2 | Known genes and pathways of the different cell types of the developing testis in mouse (modified from Wainwright and Wilhelm ) |
| PMC3279748__F2 | GSK-3 in NMDAR-LTD |
| PMC3279755__F1 | Signaling pathways of the fibroblast growth factor receptor in neural stem cells |
| PMC3279943__F1 | PI3K and STAT3: a New Alliance |
| PMC3280275__F6 | Kinome-Wide Functional Genomics Screen Reveals a Novel Mechanism of TNFAlpha-Induced Nuclear Accumulation of the HIF-1A Transcription Factor in Cancer Cells |
| PMC3280674__F1 | Fatty Heart, Cardiac Damage, and Inflammation |
| PMC3280691__F1 | Beta-catenin signaling: a novel mediator of fibrosis and potential therapeutic target |
| PMC3281071__F4 | RNA-seq Reveals Novel Transcriptome of Genes and Their Isoforms in Human Pulmonary Microvascular Endothelial Cells Treated with Thrombin |
| PMC3281082__F7 | ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer |
| PMC3281277__F1 | Proteolytic processing of the BACE1 substrates APP and NRG1 |
| PMC3281420__F1 | Schematic overview of the multifunctional roles of c-FLIP in the TRAIL-triggered apoptosis pathway as well as activating various anti-apoptotic and cell survival signaling pathways |
| PMC3281554__F2 | Possible mechanisms of regulation of DP thymocytes by multiple factors |
| PMC3281571__F1 | Simplified view of the mTOR pathway |
| PMC3281571__F2 | MTOR pathway |
| PMC3281591__F4 | Mitochondrial-dependent apoptosis |
| PMC3281607__F2 | Antioxidant roles of Prx I, Prx III, and Srx in ethanol-fed mouse liver |
| PMC3281623__F9 | Toxoplasma acquires fatty acids through a complex network of synthesis and uptake |
| PMC3281634__F1 | Simplified diagram of the unfolded protein response |
| PMC3281649__F9 | Proposed model for the inhibition of Notch1 signaling pathway by Fe65 |
| PMC3281723__F2 | Role of PHLPP in terminating oncogenic signaling pathways |
| PMC3281745__F7 | RET/PTC-mediated TRAF activation |
| PMC3282414__F2 | Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities. |
| PMC3282946__F4 | miR-23b and tretinoin, which was associated with this miRNA in thyroid cancer, shared the common target genes, ALDH1A1 and ALDH1A2 |
| PMC3282989__F2 | Recapitulation of heart development can provide useful insight for optimizing differentiation protocols |
| PMC3283059__F2 | Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway displaying transcripts in mitogen-activated protein kinase (MAPK) signaling pathway |
| PMC3283059__F4 | Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway display transcripts in cell cycle pathway |
| PMC3283443__F13 | Denitrification pathway (a) and regulation (b) in bacteria |
| PMC3283604__F6 | TSC1/2 Signaling Complex Is Essential for Peripheral Naïve CD8+ T Cell Survival and Homeostasis in Mice |
| PMC3283716__F1 | Novel Classification of Lung Cancer into Molecular Subtypes |
| PMC3283951__F5 | The acetate/mevalonate pathway for the formation of IPP, the basic five-carbon unit of terpenoid biosynthesis |
| PMC3284125__F1 | Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk |
| PMC3284544__F4 | Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis |
| PMC3284544__F5 | Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis |
| PMC3284544__F6 | Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis |
| PMC3285038__F1 | Schematic of Smads mediated TGFB signaling pathway |
| PMC3285038__F2 | Schematic summarizing the role of signaling Smads in epithelial carcinogenesis |
| PMC3285217__F1 | Drosophila signaling pathways that regulate humoral responses |
| PMC3285363__F7 | Hypothetical scheme illustrating a possible mechanism of mLDL-mediated regulation of C3 expression and secretion by human macrophages |
| PMC3285398__F1 | Toll-like Receptors (TLRs) recognize specialized structural motifs on the microbes known as pathogen-associated molecular patterns (PAMPs) |
| PMC3285398__F2 | Proposed mechanisms of interaction between TLRs and MUCs: I |
| PMC3285438__F5 | Simplified signaling pathway of the effects of resveratrol involved in metabolic control in the skeletal muscle |
| PMC3285457__F6 | Smad7 is Inactivated through a Direct Physical Interaction with the LIM Protein Hic-5/ARA55 |
| PMC3285553__F3 | Additional mechanisms by which Wnt/Beta-catenin signaling can be modulated in cancer |
| PMC3285553__F4 | Schematic illustrating numerous small molecules and biological compounds identified in the literature that inhibit Wnt/Beta-catenin signaling at various points in the pathway |
| PMC3285581__F7 | Msx Homeobox Genes Critically Regulate Embryo Implantation by Controlling Paracrine Signaling between Uterine Stroma and Epithelium |
| PMC3285584__F9 | Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway |
| PMC3286397__F11 | Campylobacter jejuni-induced Cdc42 activation |
| PMC3286676__F1 | Thyroid iodide efflux: a team effort? |
| PMC3286890__F1 | Wnt/Beta-catenin signalling and Beta-catenin role in adhesion in glioma cells |
| PMC3286973__F2 | Cell-line subtypes have unique SuperPathway network features |
| PMC3286973__F3 | Pathway diagrams can be used to predict response to therapies |
| PMC3287012__F1 | Signaling through CD44: hyaluronan binding to a receptor such as CD44 or RHAMM will cause a conformational change in the receptor |
| PMC3287202__F6 | Overview of pre-miRNA processing |
| PMC3287362__F1 | The anatomic and molecular mechanisms of sepsis-mediated sympathoexcitation and ghrelin's anti-inflammatory effect via sympathoinhibition |
| PMC3287363__F7 | Working model of ID/anemia-suppressed hippocampal IGF signaling |
| PMC3287489__F2 | Cell cycle pathway and the significant genes on cell cycle-related miRNAs |
| PMC3287586__F2 | Preimplantation development pathway |
| PMC3288148__F1 | Three pathways contribute to cellular BH4 levels, the synthesis pathway, the salvage pathway and the recycling pathway |
| PMC3288293__F1 | Molecular mechanism of senescence |
| PMC3288605__F2 | Pathway of formation and catabolism of HDL particles |
| PMC3288643__F1 | Ephs and Ephrins in Cancer: Ephrin-A1 Signaling |
| PMC3289121__F5 | IPA illustrating the predicted effect of milk removal on PI3K signaling in T lymphocytes |
| PMC3289531__F2 | A, Hepatic BCAA metabolism |
| PMC3289598__F1 | Molecular Mechanisms of Drug Resistance in Natural Leishmania Populations Vary with Genetic Background |
| PMC3289952__F1 | Selected essential fatty acids molecular mechanisms |
| PMC3289952__F2 | Proposed role of essential fatty acids in "micromanaging" molecular actions |
| PMC3290617__F1 | Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin |
| PMC3290818__F1 | TLR signalling pathway |
| PMC3290823__F3 | Possible implication of UPR in inflammatory response |
| PMC329105__F1 | Simplified schematic representation of the three well-characterized glucose-response pathways in S |
| PMC3291304__F1 | Protein quality control systems are potential targets for mechanism-based treatments of demyelinating Charcot-Marie-Tooth disease (CMT) |
| PMC3291562__F4 | Function-Based Discovery of Significant Transcriptional Temporal Patterns in Insulin Stimulated Muscle Cells |
| PMC3291637__F1 | General scheme for biogenesis of Fe-S clusters in mammalian cells |
| PMC3291637__F2 | Proposed differences in the localization of Fe-S cluster biogenesis proteins in S |
| PMC3291787__F1b | Targeting the EGFR signaling pathway in cancer therapy |
| PMC3291787__F2 | Targeting the EGFR signaling pathway in cancer therapy |
| PMC3291789__F1 | Targeting the p53 signaling pathway in cancer therapy - The promises, challenges, and perils |
| PMC3291810__F8 | PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling |
| PMC3291999__F3 | MTOR signalling pathway (see text for details) |
| PMC3292304__F4 | Gene functional association networks for selected pathways in p53 dataset |
| PMC3292309__F3 | Activation of inflammatory mediators in pancreatic Beta-cells in type 1 diabetes |
| PMC3292500__F3 | Top scored pathway map affected by BaP "Apoptosis and survival_Endoplasmic reticulum stress response" |
| PMC3292584__F4 | Differential gene expression in the TLR signalling pathway |
| PMC3292751__F3 | Regulation of mammalian mitophagy |
| PMC3292920__F1 | Diagram shows the enzyme points (in cycle) on which the effects of n-3 PUFA might operate in the homocysteine metabolic pathway of relevance |
| PMC3293036__F1 | The Wnt signaling pathway in cancer cells |
| PMC3293571__F7 | EMT downstream of TGFB and HMGA2 |
| PMC3293584__F1 | Schematic of folate-mediated one-carbon metabolism in the cytoplasm and nucleus |
| PMC3293632__F1 | Control of the EGFR pathway and cell cycle entry by miRNAs |
| PMC3293935__F4 | Known apoptotic targets of P53 |
| PMC3293992__F11 | Suppression of the NFKB Pathway by Diesel Exhaust Particles Impairs Human Antimycobacterial Immunity |
| PMC3294063__F1a | Molecular Pathways: Beta-adrenergic signaling in cancer |
| PMC3294197__F3 | Ingenuity Pathway Analysis of genes that are differentially methylated (P<1.8 × 10-6) between normal mucosa of cancer patients and controls |
| PMC3294214__F2 | Signaling pathways regulating epithelial immune response in nematode epidermal (a) and intestinal (b) cells, adapted from Tan and Shapira |
| PMC3294376__F4 | O-linked N-acetylglucosamine (O-GlcNAc) is a nutrient sensor and underlies glucose toxicity |
| PMC3294420__F2 | Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links |
| PMC3294420__F3 | Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links |
| PMC3294426__F3a | Into the Eye of the Cytokine Storm |
| PMC3294670__F7 | Mechanisms of control of Listeria entry by the type IA PI 3-kinase signaling pathway |
| PMC3294814__F1 | Proposed biosynthetic pathway of RQ (compound 1) |
| PMC329503__F9 | The roles of Ras and Mob2 in S |
| PMC3295030__F1 | Simplified description of the insulin/IGF-1 signal transduction (IIS) pathway in invertebrates and mammals |
| PMC3295063__F2 | NFKB in Aging and Disease |
| PMC3295081__F1 | Age-related Dysregulation of Inflammation and Innate Immunity: Lessons Learned from Rodent Models |
| PMC3295195__F10 | A novel mechanism linking ROS/Src/caveolin-mediated activation of the EGFR-ERK signaling pathway to chronic Ang II exposure-induced EMT in cultured renal tubular epithelial cells |
| PMC3295626__F1 | JAK-STAT intracellular signaling pathway in myelofibrosis |
| PMC3295632__F4 | Bone marrow-derived stem cell mobilization |
| PMC3295657__F6 | Pathway model for interleukin (IL)-1A and tumor necrosis factor (TNF)-Alpha-induced inhibition of human skeletal muscle cell (HuSKMC) differentiation |
| PMC3295664__F1 | Methanol utilization (MUT) pathway in P |
| PMC3295899__F2 | Matricellular Protein Thrombospondin-1 Globally Regulates Cardiovascular Function and Responses to Stress via CD47 |
| PMC3296080__F1 | Interactions between insulin-like growth factor-1 receptor (IGF-1R), insulin receptor (IR), and epidermal growth factor receptor (EGFR) signaling pathways |
| PMC3296187__F1 | Schematic representation of the RKIP signaling pathway and its effects on metastatic progression to the bone |
| PMC3296202__F1 | Pathways involved in diabetes-induced EPCs toxicity and possible strategies to reverse EPCs damage during bone marrow mobilization |
| PMC3296207__F1 | Intrinsic and exrtinsic pathways of anoikis |
| PMC3296254__F5 | Arginine metabolic network |
| PMC3296254__F7 | Lysine biosynthetic pathway |
| PMC3296744__F11 | Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development |
| PMC3296768__F5 | Targeting Bone Remodeling by Isoflavone and 3,3'-Diindolylmethane in the Context of Prostate Cancer Bone Metastasis |
| PMC3296807__F1 | Oncogenes and tumor suppressors associated with the regulation of autophagy |
| PMC3296959__F2 | Innate immunity and the ubiquitin-proteasome system in PD |
| PMC3297025__F1 | IL-1 signaling leads to actin stress fiber formation |
| PMC3297025__F2 | BTB restructuring and spermiation are coordinated by IL-1A during spermatogenesis |
| PMC3297581__F6 | Tcf7 Is an Important Regulator of the Switch of Self-Renewal and Differentiation in a Multipotential Hematopoietic Cell Line |
| PMC3298518__F2 | Pathogenesis of neurodegenerative diseases is significantly associated with oxidative stress |
| PMC3298530__F7 | Tentative scheme for luteolin regulation of the IGF-IR signaling pathway in HT-29 human colon cancer cells |
| PMC3298572__F7 | Model for HuR NEDDylation |
| PMC3298638__F2 | Screening for small molecule inhibitors of embryonic pathways: Sometimes you gotta crack a few eggs |
| PMC3298733__F1 | New therapies targeting the deregulated pathways to treat TICs in pancreatic cancer |
| PMC3298845__F1 | Wnt/Beta-catenin signaling pathway in liver biology and disease |
| PMC3299304__F3 | Molecular mechanisms of HGF-c-Met-mediated signaling for inhibiting TLR4-mediated NFKB activation in macrophages |
| PMC3299342__F3 | Signaling by PERK, IRE1, and ATF6 |
| PMC3299554__F1 | Diagrammatic representation of the Akt signaling pathway.Notes: Activation of receptor tyrosine kinase (RTK) by growth factor binding activates PIK3 |
| PMC3302314__F1 | Signaling cascade following TLR2/TLR4, TLR7/TLR8, and TLR3 activation with envelope glycoprotein, ssRNA, and dsRNA, respectively |
| PMC3302314__F2 | Left half, signaling via IPS-1 following dsRNA/ssRNA recognition by RIG-I and MDA5 |
| PMC3302843__F10 | Hypoxia Reduces Arylsulfatase B Activity and Silencing Arylsulfatase B Replicates and Mediates the Effects of Hypoxia. |
| PMC3303469__F1 | Hypoxia inducible factor (HIF) pathway |
| PMC3303474__F3 | Bibliosphere network of ubiquinol-sensitive genes regulated in liver tissues of C57BL6J mice |
| PMC3303581__F1 | Myostatin signals through the ActRIIB-ALK4/5 heterodimer activate Smad2/3 with blocking of MyoD transactivation in an autoregulatory feedback loop |
| PMC3303591__F1 | Stimulation of PI-3K/Akt signaling pathway after activation of IR/IGF-1R mediates insulin neuroprotection against damaging conditions |
| PMC3303610__F3 | Ang-(1-7) signaling in cardiomyocytes |
| PMC3303613__F1 | Signaling pathways in the pathogenesis of nasopharyngeal carcinoma (NPC) |
| PMC3303816__F3 | Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis |
| PMC3303935__F1 | Toll-Like Receptors in Chronic Pain |
| PMC3304298__F1 | AKT signaling pathway |
| PMC3304564__F1 | PI3K/AKT signaling module and cross-talk with other pathway |
| PMC3304673__F1 | Association of the canonical interferon pathway with the IRF5 haplotype |
| PMC3305403__F4 | The Nucleoside Diphosphate Kinase Gene Nme3 Acts as Quantitative Trait Locus Promoting Non-Mendelian Inheritance |
| PMC3305973__F2 | Sixteen genes associated with enzastaurin response were established by pathway analyses and prediction of drug response using an eight-gene signature |
| PMC3306173__F6 | Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis |
| PMC3306451__F2 | Integration of mitochondrial oxidative and antioxidant pathways by PGC-1A |
| PMC3306610__F1 | Targeting Apoptosis Pathway with Natural Terpenoids: Implications for Treatment of Breast and Prostate Cancer |
| PMC3306972__F1 | ABPP processing, the adaptor proteins interacting with its intracellular domain and the pathway leading to ERK1/2 activation |
| PMC3306981__F1 | Summarized the signaling mechanisms of various matricellular proteins contributing to cancer progression |
| PMC3307000__F3 | JNK signaling pathway regulates axonal transport and autophagy |
| PMC3307371__F8 | Exercise can increase small heat shock proteins (sHSP) and pre- and post-synaptic proteins in the hippocampus |
| PMC3307881__F5 | Inhibition of the Nedd8 system sensitizes cells to DNA Inter-strand crosslinking agents |
| PMC3307887__F1 | Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells. |
| PMC3307952__F7 | Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype |
| PMC3307959__F5 | Unconventional roles of kinesins in cell signaling |
| PMC3307977__F6 | Schematic diagram of the FGF2-STAT3-PAX3 signaling pathway |
| PMC3308137__F2 | miRNAs that promote or inhibit tumorigenesis provide diverse functions within oncogenic and tumor suppressor signaling pathways |
| PMC3308858__F8 | How GSK3B phosphorylation is involved with microtubule destabilization |
| PMC3309175__F7 | Mammalian target of rapamycin (mTOR) signaling pathway for the regulation of skeletal muscle protein synthesis in response to growth factors, nutrition, and mechanical stimuli |
| PMC3309495__F2 | Pathway analysis of altered metabolites upon paroxetine treatment |
| PMC3309723__F5 | Parp1 mediation of Sox2 activity in ESC pluripotency |
| PMC3309773__F7 | The functional role of Akt1, EMSY, and BRCA2 in the regulation of ISGs |
| PMC3309773__F1 | Regulation of ISGs by Akt1 and EMSY |
| PMC3309874__F1 | Insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS) is a major candidate pathway in human longevity |
| PMC3309942__F1 | Interaction motifs and domains of RANKL signal intermediaries |
| PMC3309942__F2 | p62 in osteoclast signaling and protein trafficking |
| PMC3310050__F12 | Folate Decorated Dual Drug Loaded Nanoparticle: Role of Curcumin in Enhancing Therapeutic Potential of Nutlin-3a by Reversing Multidrug Resistance |
| PMC3310155__F1 | Model of CaS receptor sorting traffic |
| PMC3310197__F7 | Interactions of signaling by ER stress, oxidative stress, and cytokines with the pathways of autophagy: Induction of autophagy requires the assembly of Beclin-1 with class III PI 3 kinase (Vps34) and UVRAG |
| PMC3310225__F10 | Protein Kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development |
| PMC3310485__F4 | Schematic of the role of BDNF in the brain reward pathway associated with addiction |
| PMC3310713__F3 | Dual nature of Myc induced DDR |
| PMC3310792__F8 | Dengue Virus Infection Perturbs Lipid Homeostasis in Infected Mosquito Cells |
| PMC3310826__F16 | Schematic showing alterations to the TAG biosynthesis pathway in AS11 when DGAT1 activity is absent |
| PMC3310875__F6 | Progesterone Receptor Activates Msx2 Expression by Downregulating TNAP/Akp2 and Activating the Bmp Pathway in EpH4 Mouse Mammary Epithelial Cells |
| PMC3311240__F11 | Muscle cell signaling in response to 1E3 |
| PMC3311515__F1 | Scheme for the intracellular renal RAS on the nuclear membrane |
| PMC3311926__F1 | Mitochondrial regulation of apoptosis |
| PMC3311998__F6 | Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate |
| PMC3312242__F1 | Regulation of cancer stem cells by inflammatory cytokine networks |
| PMC3312283__F2 | This figure shows three novel intracellular signaling pathways involved in the pathogenesis of IBD |
| PMC3312480__F1 | Schematic view of potential targets and site of action of some biologics in IBD |
| PMC3312677__F8 | Genetic pathways involved in the regulation of the Mesp2 pathway |
| PMC3312932__F2 | Regulation of the human catalytic subunit of telomerase (hTERT) |
| PMC3312985__F4 | Genes identified as part of the significant Para-ICA networks highlighted on a KEGG Alzheimer's pathway diagram derived from the DAVID functional association tool |
| PMC3312987__F2 | Commonly mutated pathways in glioblastoma |
| PMC3313080__F2 | Endoplasmic Reticulum Stress, the Unfolded Protein Response, Autophagy, and the Integrated Regulation of Breast Cancer Cell Fate |
| PMC3313452__F4 | The noncanonical NFKB pathway |
| PMC3313462__F4 | Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes |
| PMC3313594__F3 | Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery |
| PMC3313594__F5 | Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery |
| PMC3313666__F7 | Outline of the mevalonate pathway |
| PMC3313874__F2 | Networks built using differentially expressed genes in uninfected macrophages from C57BL/6 and CBA mice |
| PMC3313983__F5 | Associations between HIV and Human Pathways Revealed by Protein-Protein Interactions and Correlated Gene Expression Profiles |
| PMC3314429__F2 | miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma |
| PMC3314445__F9 | An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease-associated AB oligomers |
| PMC3314478__F1 | Parkinson's disease: don't mess with calcium |
| PMC3314482__F1 | Chk'ing p53-deficient breast cancers |
| PMC3314616__F2 | Methamphetamine Causes Differential Alterations in Gene Expression and Patterns of Histone Acetylation/Hypoacetylation in the Rat Nucleus Accumbens |
| PMC3314677__F9 | Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress in Human Prostate Cancer Cells by n-butylidenephthalide |
| PMC3314865__F3 | Targeting Mutant BRAF in Melanoma: Current Status and Future Development of Combination Therapy Strategies |
| PMC3315189__F1 | S-ADENOSYLMETHIONINE TREATMENT OF ALCOHOLIC LIVER DISEASE: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL |
| PMC3315209__F6 | Speculative model for the role of the Hippo pathway in germ cell tumorigenesis and reprogramming |
| PMC3315368__F4 | Gene Array Data from CWR22RV1 xenografts treated with PD325901 for three weeks |
| PMC3315579__F4 | Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era |
| PMC3315606__F1 | Roles for prions and protein-only inheritance in cancer |
| PMC3315682__F1 | Serine biosynthetic pathway |
| PMC3315683__F1 | Phosphatidylinositol 3-kinase signaling pathway |
| PMC3316122__F2 | Schematic model depicting activation of the AIM2 inflammasome by F |
| PMC3316585__F1 | Formal Modeling and Analysis of the MAL-Associated Biological Regulatory Network: Insight into Cerebral Malaria |
| PMC3316754__F5 | Ingenuity pathway analysis was used to create a network of biologically relevant genes regulated in response to diet for comparisons control versus diet A, control versus diet B, and diet C versus diet B |
| PMC3316934__F4 | Significant differences in mRNA expression were seen for genes involved in the JNK signaling pathway between tumors arising in different CNS locations |
| PMC3316974__F1 | AKT-mTOR signaling pathway showing rapamycin inhibition sites in astrocytomas |
| PMC3317017__F4 | Altered signaling pathways and inhibitors |
| PMC3317163__F2 | One-carbon metabolism |
| PMC3317170__F1 | The activation of TLR2 by Leishmania sp., leading to a proinflammatory (left), or anti-inflammatory arm (centre and right) |
| PMC3317170__F3 | Proposed models for the activation of intracellular TLR9 and TLR3 by Leishmania |
| PMC3317213__F4 | Metabolism of xenobiotics by cytochrome P450 pathway, and ribosome map views of identified proteins |
| PMC3317229__F4 | P38 signalling cascade (adapted from http://www.sabiosciences.com/) |
| PMC3317271__F1 | Simplified scheme of cell death and survival pathways involved in ALF |
| PMC3317440__F2 | Strain-specific host gene networks activated in Mtb-infected BMM |
| PMC3317641__F6 | Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes |
| PMC3317641__F7 | Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes |
| PMC3317991__F6 | RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer |
| PMC3318211__F1 | Signaling pathways involved in anthracycline-induced cardiomyocyte injury |
| PMC3318588__F8 | Subnetwork of functional interactions of ESRP-target networks |
| PMC3318612__F8 | Summary model of rAdV-sensing cascades in RAW 264.7 cell line |
| PMC3318683__F12 | A model of MMP-9 sorting and trafficking in activated macrophages |
| PMC3318714__F8 | Proposed model for the role of SPHK/phyto-S1P and PLDA1/PA in the ABA-mediated stomatal closure signaling pathway |
| PMC3318742__F8 | Model of how RACK1 mediates activation of SHH/GLI signaling in NSCLC Cells |
| PMC3319201__F3 | Primary therapeutic targets in the Ras downstream signaling pathway |
| PMC3319314__F3 | APE1 role in DNA base excision repair (BER) |
| PMC3319358__F1 | Gut triglyceride production |
| PMC3319358__F2 | Gut triglyceride production |
| PMC3319453__F2 | Insulin, IGF-I and IGF-II binding to IR and IGF-IR |
| PMC3319470__F1 | Coenzyme Q10biosynthetic pathway and electron transport role in the mitochondrial respiratory chain |
| PMC3319488__F1a | Pancreatic Ductal Adenocarcinoma: A Review of Immunologic Aspects |
| PMC3319521__F1 | The CD47-SIRPA Pathway in Cancer Immune Evasion and Potential Therapeutic Implications |
| PMC3319771__F2 | Convergence of miR-21 target genes and the apoptosis pathway |
| PMC3319919__F2 | Components of the TLR pathway and genes commonly induced during the innate immune response of zebrafish to bacterial infection |
| PMC3320915__F7 | Model of proposed CCR7/CCL19 signaling pathway in T cells |
| PMC3320973__F8 | Wnt signaling regulation induced by cell surface HSPG desulfation during dentinogenesis |
| PMC3321152__F4 | Non-apoptotic functions of apoptosis-regulatory proteins |
| PMC3321211__F4 | Apoptotic cascade |
| PMC3321306__F1 | Gene expression network of the heritable transcripts in the nuclear factor kappa B signaling pathway |
| PMC3321383__F2 | Linking Lipids to Alzheimer's Disease: Cholesterol and Beyond |
| PMC3321453__F6 | Vitamin D pathway and sites of interaction with dietary factors |
| PMC3321461__F1 | Proposed mechanism for overcoming HNSCC resistance to EGFR antagonists using PI3kinase/Akt/mTOR and NFKB-IL6-STAT3 pathway inhibitors |
| PMC3321553__F2 | Coregulation of gene transcription by p53 and Smad complexes |
| PMC3321615__F1 | Canonical and noncanonical pathways of NFKB activation |
| PMC3321808__F4 | Differential regulation of genes in the IL-10 pathway in neonates and school-age children with septic shock versus age-matched controls |
| PMC3321808__F5 | Differential regulation of genes in the antigen presentation pathway in neonates and school-age children with septic shock versus age-matched controls |
| PMC3322137__F3 | Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal Transition |
| PMC3322224__F2 | cAMP Signaling CascadeLigand binding (represented in this example by PTH, but other ligands and receptors can stimulate cAMP synthesis), activates GsA and stimulates cAMP synthesis by adenylate cyclase |
| PMC3322338__F1 | Hypothetical model for neuroimmune-related actions of miRNAs in brain of human alcoholics (e.g., in microglia) |
| PMC3322527__F7 | TGFB signaling pathway overlaid with differentially expressed genes |
| PMC3322580__F4 | Enrichment and submodularization of cell cycle in terms of E3-mediated regulatory modules |
| PMC3322992__F8 | Pathways required for the role of CDCP1 in EGF/EGFR-induced cell morphological changes and increased cell migration |
| PMC3323126__F3 | Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus |
| PMC3323190__F7 | Summary of the effects of leptin in the hypothalamus of control (A) and ob/ob mice (B), as revealed by Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) and 13C High-Resolution-Magic Angle Spinning (HR-MAS) |
| PMC3323522__F7 | A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity |
| PMC3323563__F8 | Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2 |
| PMC3323758__F4 | DNA base excision repair: A mechanism of trinucleotide repeat expansion |
| PMC3323831__F1 | TLR signalling |
| PMC3323875__F3 | Feedback inhibition mediated by the PI3K/AKT/mTOR pathway |
| PMC3323898__F5 | Graphical representation of the known connections between the Wnt/Beta-catenin pathway and the Notch1 signaling pathways, according to the knowledge of the current literature |
| PMC3324026__F1 | Annotation of the insulin/TOR network in Apis showing methylated and differentially methylated genes |
| PMC3324133__F1 | Insulin receptor (INSR) belongs to a family of receptor tyrosine kinases that includes the receptor for insulin-like growth factor 1 (IGF-1R) |
| PMC3324360__F5 | Simplified TGFB pathway |
| PMC3324906__F1 | Pivotal role of E-cadherin, Beta-catenin, and transforming growth factor B (TGFB) and Wnt signaling pathways in an epithelial-mesenchymal transition (EMT) program |
| PMC3324922__F3 | ALDH1A1 pathway |
| PMC3324922__F4 | NOS3 pathway |
| PMC3325001__F1 | Hh signaling pathway |
| PMC3325001__F2 | Modes of Hh pathway signaling |
| PMC3325226__F3 | A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study |
| PMC3325426__F1 | The miRNA biosynthesis pathway from the nucleus to the cytosol |
| PMC3326643__F2 | Targeting Mnks for Cancer Therapy |
| PMC3327653__F1 | Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway |
| PMC3327812__F7 | Protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of GPS2 |
| PMC3328211__F2 | Arterial-venous and lymphatic specification in vertebrate embryo |
| PMC3328216__F1 | CCM3 interacts with multiple signaling complexes |
| PMC3328281__F1 | Molecular changes of serous carcinogenesis |
| PMC3328302__F7 | Schematic diagram illustrating the proposed interaction between CDH17 and Wnt/Beta-catenin pathway during HCC progression |
| PMC3328452__F8 | Identification of Protein Networks Involved in the Disease Course of Experimental Autoimmune Encephalomyelitis, an Animal Model of Multiple Sclerosis |
| PMC3328638__F1 | Glucose, fatty acid (FA) and glutamine metabolic pathways |
| PMC3328674__F1 | Exercise-stimulated glucose uptake in skeletal muscle |
| PMC3328790__F1 | TGFB signaling pathway and its integration with other major pathways that is likely to be involved in the pathogenesis of cardiovascular diseases in elderly patients |
| PMC3328827__F2 | Beyond inactivation of the MEN1 gene, additional mutations in other genes may be responsible for acceleration of tumor growth, thus involving a process of multistep tumorigenesis |
| PMC3328839__F6 | Proposed pathway |
| PMC3328890__F1 | ROS-dependent and -independent apoptosis induced by particulate pollutants |
| PMC3328896__F2 | Cbl-b functions as central gate keeper of T-cell activation |
| PMC3328908__F9 | Diagram of canonical tight junction signaling pathway |
| PMC3328908__F10 | Diagram of canonical actin cytoskeleton signaling pathway |
| PMC3329340__F3 | Simplified TOR signaling network with known Arabidopsis homologs in Italic writing |
| PMC3329512__F3 | The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism |
| PMC3329512__F4 | The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism |
| PMC3329512__F7 | The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism |
| PMC3329953__F8 | mTOR pathway in aging |
| PMC3329985__F4 | Top Networks Associated With MK-801 Treatment Identified by Ingenuity Pathway Analysis |
| PMC3331679__F2 | mTOR signaling in growth control and disease |
| PMC3331689__F3 | Regulation of hepcidin by iron and inflammation |
| PMC3331705__F1 | Tumor suppressors and oncogenes in the Wnt pathway |
| PMC3331761__F4a | Concordance of Changes in Metabolic Pathways Based on Plasma Metabolomics and Skeletal Muscle Transcriptomics in Type 1 Diabetes |
| PMC3332287__F2 | Wnt signaling pathway participated in the activation of hepatic stellate cells |
| PMC3333776__F2 | Rhizosphere-induced genes in Rlv3841 metabolic pathways |
| PMC3334407__F5 | Schematic model for inhibition of cell proliferation by EGCG analogs |
| PMC3334466__F1 | Duo/Cdc42 pathways |
| PMC3334516__F4 | TGFB signaling pathway members and potential pathway member LRG1 |
| PMC3334602__F7 | Cordycepin analogues and the C |
| PMC3334621__F7 | IsomiRs and miRNAs target similar biological pathways |
| PMC3334709__F4 | Tau neuroinflammatory cascade |
| PMC3334867__F5 | Inborn Errors of Human JAKs and STATs |
| PMC3334885__F1 | T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice |
| PMC3334963__F7 | Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing |
| PMC3334963__F8 | Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing |
| PMC3334999__F5 | Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation |
| PMC3334999__F6 | Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation |
| PMC3335081__F9 | Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation |
| PMC3335094__F3 | Mechanical Strain Regulates Osteoblast Proliferation through Integrin-Mediated ERK Activation |
| PMC3335376__F4 | Illustration of p53 TIAs in lymphocytes |
| PMC3335376__F8 | Therapeutic modulation of the TP53 pathway |
| PMC3335396__F1 | Ligand-dependent activation of the Hh pathway |
| PMC3335670__F3 | Action of the enteropathogenic yersiniae Ysc T3SS effectors (Yops) on host cell signaling and survival |
| PMC3335800__F8 | MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells |
| PMC3335841__F2 | Reduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation |
| PMC3335841__F3 | Reduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation |
| PMC3335850__F1 | Gene Expression Analysis Implicates a Death Receptor Pathway in Schizophrenia Pathology |
| PMC3335938__F1 | Key therapeutic targets in the PI3K/Akt and MAPK pathways together with pharmacological agents inhibiting members of these signaling cascades |
| PMC3336023__F3 | Chronic alcohol exposure alters gene expression in HepG2 cells |
| PMC3336023__F4 | Chronic alcohol exposure alters gene expression in HepG2 cells |
| PMC3336066__F2 | Double-strand break repair in mammalian cells |
| PMC3336107__F1 | The Unfolded Protein Response in the ER |
| PMC3336361__F4 | Apoptosis pathways |
| PMC3336771__F1 | Endogenous polyamines potentiate macrophage polarization |
| PMC3337162__F2 | Polarization of migrating cortical neurons by Rap1 and N-cadherin |
| PMC3337163__F1 | Breaking up is hard to do |
| PMC3337621__F2 | Phosphoinositide 3-Kinase Signaling in Intestinal Inflammation |
| PMC3337681__F7 | Putative inhibitory pathway of inflammatory signaling events by CA |
| PMC3337715__F1 | Phosphoinositide-3 kinase signaling in cardiac hypertrophy and heart failure |
| PMC3337844__F1 | Autophagic proteins |
| PMC3337981__F8 | BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NFKB pathway |
| PMC3338086__F1 | Canonical and non canonical NF-kB pathways and related drugs inhibition |
| PMC3338129__F2 | Crosstalk Between Reverse Cholesterol Transport and Innate Immunity |
| PMC3338196__F3 | Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation |
| PMC3338341__F1 | Repressed (left) and activated (right) canonical HH signaling pathways |
| PMC3338341__F2 | Mechanisms of activation of HH signaling in hematological cancers |
| PMC3338536__F4 | TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators |
| PMC3338606__F6 | Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Toll-Like Receptor-4 and NFKB Signalling |
| PMC3338748__F1 | High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism |
| PMC3339861__F3 | EGF decreases sphingolipid biosynthesis transcripts |
| PMC3339861__F4 | EGF decreases free fatty acid (FFA) biosynthesis transcripts |
| PMC3339894__F2 | Putative molecular mechanisms of Wnt signaling, lipid metabolism, and IL-6 effects on insulin signaling in nonobese PCOS adipose tissue |
| PMC3340185__F5 | A model for the XIAP-regulated RhoGDI SUMOylation signaling pathway in modulation of cell motility |
| PMC3340193__F8 | Scheme to explain the increased production of HA in fro/fro (NSMase2-/-) mouse fibroblasts |
| PMC3340256__F1 | tBID structure and mechanism of action |
| PMC3340361__F1 | RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans |
| PMC3340364__F6 | Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells |
| PMC3340543__F6 | BRCA1 functions independently of homologous recombination in DNA interstrand cross-link repair |
| PMC3340722__F2 | TNF related apoptosis-inducing ligand and its receptors in ocular tumors |
| PMC3341105__F2 | Signal transducer and activator of transcription 3 (Stat3) signaling |
| PMC3341446__F1 | Illustration of the PI3K pathway signaling pathway |
| PMC3341711__F1 | TGFB/Smad canonical signaling pathway |
| PMC3342043__F1 | TLR2 signaling |
| PMC3342049__F2 | Autophagy within antigen donor cells and cross-priming |
| PMC3342058__F2 | Major therapeutic targets for inhibition of donor-reactive memory T cell responses |
| PMC3342067__F4 | CD44 potentiates T cell activation, expansion, contraction, and maintenance of memory cells |
| PMC3342071__F2 | FcERI signaling events in WT, NTAL-/-, and LAT-/- cells |
| PMC3342073__F3 | Possible signaling pathway activated by the phytol-based immunostimulant PHIS-01 |
| PMC3342110__F1 | Signaling pathways important for C |
| PMC3342334__F9 | Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway |
| PMC3342348__F1 | IL-1 signaling in the tumor microenvironment |
| PMC3342359__F1 | Three types of autophagy and cellular and molecular events in an autophagic pathway |
| PMC3342359__F2 | Autophagy induction by TLR stimulation |
| PMC3342364__F2 | Molecular mechanisms mediating the regulatory effects of hypoxia |
| PMC3342401__F7 | Summary diagram of the proposed ADM signaling pathway in retina |
| PMC3342562__F6 | Schematic representation of the role of H2S in atherosclerosis |
| PMC3342586__F4 | Salmonella central carbon metabolism |
| PMC3342643__F3 | Diacylglycerol kinases in immune cell function and self-tolerance |
| PMC3342643__F5 | Diacylglycerol kinases in immune cell function and self-tolerance |
| PMC3343040__F6 | Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease |
| PMC3343040__F7 | Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease |
| PMC3343135__F2 | Differential expression of mRNA and proteins encoding factors in the Notch signaling pathway |
| PMC3343154__F3 | Mammalian unfolded protein response (UPR) pathways |
| PMC3343200__F5 | IL-6 contributes to a positive feedback cycle of growth and invasion between CAFs (myofibroblasts) and its underlying tumor (afferent pathway) and between invading tumor and the recruitment of fibroblasts to myofibroblasts (efferent pathway) |
| PMC3343318__F6 | PLC signaling in B cells |
| PMC3343650__F5 | Three major signaling pathways are altered in prostate cancers |
| PMC3343703__F1 | Heme metabolism |
| PMC3344210__F4 | The effects of curcumin on the TNFA receptor and its downstream signaling pathway |
| PMC3344687__F7 | Schematic diagram of the Heme/TLR4/MyD88 and/or TRIF hypothesis in ICH |
| PMC3344904__F1 | High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery |
| PMC3345192__F1a | MYC on the Path to Cancer |
| PMC3345255__F1 | MAPK/ERK signaling and the hallmarks of cancers |
| PMC3345303__F2 | Neural and Cellular Mechanisms of Fear and Extinction Memory Formation |
| PMC3346111__F7 | Overall scheme of hypothetical effect of endocannabinoid signaling in human melanocytes |
| PMC3346695__F2 | Cell signaling pathways involved in ischemic postconditioning |
| PMC3346698__F5 | The main chain path of pheromone response pathway (b) the assembly paths detected by Scott et al |
| PMC3346698__F8 | One of the KEGG prostate cancer pathways (b) the paths detected by our method |
| PMC3346900__F4 | (A, B) Schematic view of the Fas/Fas-ligand (FasL) apoptotic signaling pathway |
| PMC3346964__F1 | Four major molecular pathways activated by tyrosine kinase receptor B (TrkB) and IGF-1 receptor (IGF-1R) |
| PMC3346990__F3 | The potential molecular mechanisms of crosstalk between nuclear receptors LXR and FXR-SHP-LRH-1 regulatory cascade in the liver and intestine |
| PMC3347034__F3 | Inhibition of type I IFN signaling by DENV: IFNA/B binds the type I IFN receptor (IFNAR), which is composed of IFNAR1 and IFNAR2 and is found on the surface of nucleated cells |
| PMC3347317__F2 | Modulation of type I IFN production by PRRSV |
| PMC3348077__F7 | Signaling pathway for the cytoprotective effect of STI571 in TRAIL-treated colon cancer cells |
| PMC3348384__F1 | miRNAs and estrogen action |
| PMC3348393__F1 | Cellular Senescence and Cancer Chemotherapy Resistance |
| PMC3348440__F1 | Target-derived NGF mediates axon growth and synapse assembly in sympathetic neurons via endocytic signaling mechanisms |
| PMC3348497__F1 | Insulin-like growth factor (IGF)-1 signal transduction |
| PMC3348846__F2 | Leukocyte recruitment to sites of injury/infection: dominant role of ROS |
| PMC3348964__F1 | Metabolic pathway for disulfiram in humans |
| PMC3348998__F1 | Lipids and Prostate Cancer |
| PMC3349255__F7 | Schematic diagram of a cross-regulation network between FOXA1 and the ErbB2 signaling pathway in ER-negative breast cancer |
| PMC3349304__F6 | Identification of transcripts and proteins associated with hemocytes |
| PMC3349963__F1 | Canonical and non-canonical IL-13 signaling in cells |
| PMC3350083__F1 | Overlap in FcERI, FcGRIII, and FcGRIIB signaling |
| PMC3350790__F1 | Dmrt genes integrate sex-specific, spatial, and temporal cues to induce sexually dimorphic differentiation in restricted groups of cells |
| PMC3350990__F2 | Bioinformatic analysis of the differentially expressed proteins.The list of the MS-identified protein spots from 2D-DIGE was subjected to String (v |
| PMC3351101__F2 | Regulation of cytoplasmic mRNA decay |
| PMC3351275__F3 | Negative feedback and adaptive resistance to the targeted therapy of cancer |
| PMC3351290__F10 | TRPC1 channel is a major regulator of EGFR signaling |
| PMC3351343__F6 | Working model for onset of emphysema in Fut8+/- mice upon exposure to CS |
| PMC3351347__F7 | Control of Pax3 expression in the caudal neurectoderm via NCE2 |
| PMC3351834__F2 | Transcriptional changes in TGFB1 signaling pathway |
| PMC3352318__F4 | Association of cytoplasmic peptidyl Cys with functional networks according to reduction and oxidation of Cys residues |
| PMC3352318__F6 | Association of nuclear peptidyl Cys with functional networks according to reduction and oxidation of Cys residues |
| PMC3352318__F7 | Association of mitochondrial peptidyl Cys with functional networks according to reduction and oxidation of Cys residues |
| PMC3352961__F3 | Brain, blood, and iron: Perspectives on the roles of erythrocytes and iron in neurodegeneration |
| PMC3353386__F5 | NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways |
| PMC3353643__F6 | Proposed model of WNK4 signaling pathway mediating NCC regulation in DCT |
| PMC3353781__F8 | Signaling pathways mediating Beta-adrenergic effects on the cardiac microtubule network |
| PMC3353888__F1 | Adrenergic Alpha-1 Pathway Is Associated with Hypertension among Nigerians in a Pathway-focused Analysis |
| PMC3354586__F3 | Ingenuity pathway analysis (IPA) identified critical expression networks containing genes that are significantly correlated with the extent of necrosis in The Cancer Genome Atlas (TCGA) glioblastoma (GBM) samples from all subclasses (A and B) |
| PMC3355325__F2 | Two distinct DC semi-maturation pathways induce different types of regulatory T cells |
| PMC3355540__F2 | Nuclear receptors and photoreceptor differentiation in mice |
| PMC3355730__F2 | Co-expression of genes involved in lignin formation across species |
| PMC3355751__F1 | Oxylipin biosynthesis pathway and signal transduction in Arabidopsis thaliana |
| PMC3355838__F1 | Step model of thyroid carcinogenesis |
| PMC3355838__F2 | Genetic events involved in thyroid tumor initiation and progression |
| PMC3355838__F3 | Wnt signaling pathways |
| PMC3355898__F2 | Somatic alterations in the PI3K pathway in prostate cancer |
| PMC3355926__F1 | Activation of the Pi3K/Tor pathway by insulin and glutamate |
| PMC3355932__F2 | Anaplastic lymphoma kinase signaling |
| PMC3355940__F2 | K63-linked polyubiquitination in the activation of canonical and non-canonical NFKB signaling pathway |
| PMC3355967__F1 | Schematic of exosome secretion in a cancer cell model |
| PMC3355968__F1 | Regulation of FOXO3 and Beta-catenin by AKT, ERK, and IKK signaling pathway |
| PMC3355968__F2 | Regulation of Mcl-1 and Snail by AKT, ERK, and IKK signaling pathway |
| PMC3356006__F2 | Central regulation of leptin signaling, autonomic innervation of the adipocyte and Beta-cell, and the starvation response |
| PMC3356053__F10 | Most significant canonical pathway from this study |
| PMC3356061__F2 | Molecular pathway of activation of autophagy |
| PMC3356073__F1 | Phosphatidylinositol 3-kinase (PI3K) signaling cascade |
| PMC3356080__F4 | Factors and molecular mechanisms that influence ecdysone synthesis and the timing of critical weight attainment |
| PMC3356111__F9 | Schematic representation of TNF's dual effect on rat pinealocytes |
| PMC3356304__F6 | Personalized Pathway Enrichment Map of Putative Cancer Genes from Next Generation Sequencing Data |
| PMC3356354__F8 | High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes |
| PMC3356354__F9 | High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes |
| PMC3356354__F10 | High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes |
| PMC3356574__F3 | The signaling pathways regulating radiation-induced bystander effects through expression and secretion of soluble biologically active factors |
| PMC3356660__F1 | A model summarizing the results of the study in which the miR-301a molecule inhibits the PIAS3 enzyme, resulting in the promotion of the IL-6/23 receptor-STAT3 pathway and stimulation of Th17 differentiation |
| PMC3356707__F1 | Canonical WNT signaling pathway |
| PMC3356999__F1 | Fatty acid regulation of hepatic lipid metabolism |
| PMC3357314__F4 | Regulation of CTGF Expression by TGFB1 in OsteoblastsTGFB1 induction of CTGF in osteoblasts requires Src, Smad and ERK signaling |
| PMC3357406__F3 | Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development |
| PMC3357464__F3 | Scaffolds can organize pleiotropic kinases into stimulus-specific signaling modules to direct them to one specific pathway |
| PMC3357465__F1 | Gene mutations involved in PTC carcinogenesis |
| PMC3357504__F2 | Translation initiation control during growth factor stimulation, cellular stress, and cellular physiology |
| PMC3357504__F3 | Translation initiation control relays signals to erythroid and granulocytic differentiation |
| PMC3357548__F3 | TWEAK signaling pathway: illustration of the TWEAK signaling pathway as visualized in NetSlim web page |
| PMC3357552__F1 | Overview of TLR signaling |
| PMC3357552__F7 | TLR4 signaling in alcoholic steatohepatitis and fibrosis |
| PMC3358449__F1 | Key components in the regulation of methionine metabolism |
| PMC3358492__F1 | Emerging Therapies for Systemic Lupus Erythematosus - Focus on Targeting Interferon-alpha |
| PMC3358519__F1 | Schematic diagram of the cholinergic anti-inflammatory pathway (CAP) |
| PMC3358533__F5 | PPARA signaling canonical pathway in chronic arsenic-exposed lung epithelial cells |
| PMC3358876__F1 | H. pylori-induced miR-155 expression in macrophage immune cells |
| PMC3359066__F5 | Identification of Functional Differences in Metabolic Networks Using Comparative Genomics and Constraint-Based Models |
| PMC3359076__F5 | Regulation of thrombin-induced RelA/p65 nuclear translocation by the Rho-actin pathway |
| PMC3359119__F1 | mTORC1 signaling and regulation of pancreatic Beta-cell mass |
| PMC3359223__F1 | Glycolysis metabolic pathway |
| PMC3359641__F3 | Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors. |
| PMC3359655__F1 | Central IR/IGF-1 signaling |
| PMC3359728__F3 | Regulation of homeostatic AMPAR trafficking and turnover |
| PMC3359746__F1 | Several growth factor signals activate cell membrane receptor tyrosine kinases leading to activation of downstream interacting signal transduction pathways (PI3K/AKT, RAF/MAPK, and MTOR) |
| PMC3359833__F2 | Linking pathways to disease: Crohn's disease (from Wang et al |
| PMC3360100__F3 | Examples of signal transduction pathways in astroglial cells following P2Y1R activation |
| PMC3360162__F2 | Antigen-mediated chemotaxis |
| PMC3360162__F4 | Synthesis of eicosanoids and their actions in mast cells |
| PMC3360606__F1 | Integrative Gene Regulatory Network Analysis Reveals Light-Induced Regional Gene Expression Phase Shift Programs in the Mouse Suprachiasmatic Nucleus |
| PMC3360921__F8 | IQGAP1 regulates cell homeostasis through mTORC1 |
| PMC3360922__F1 | Murine mutants in the study of systemic iron metabolism and its disorders: an update on recent advances |
| PMC3361329__F2 | Signaling pathways of TNFAlpha-induced hepatocyte death |
| PMC3361414__F5 | Schematic representation of the interplay of T7 gp5.5, gp3, E |
| PMC3361581__F1 | Depiction of arachidonic acid signaling pathway highlighting genes measured in this study |
| PMC3361622__F4 | Recent developments on immunotherapy for brain cancer |
| PMC3361678__F1 | Many host factors are involved at each step of the HCV life cycle, which starts with virus binding to its specific receptors (CD81, CLDN1, OCLN, and SR-BI) |
| PMC3361682__F2 | UCB interaction with neural plasma membrane (A) and pathways by which UCB may affect neuronal function (B) |
| PMC3362209__F1 | RIP-1 in programmed necrosis |
| PMC3362297__F11 | Proposed roles of the calcineurin signaling cascade in stress responses, drug tolerance, and virulence in C |
| PMC3362516__F1 | Mitochondrial Ca2+ influx and efflux mechanisms |
| PMC3362922__F1 | Hexosamine biosynthetic pathway and its dependent processes |
| PMC3362995__F5 | The WNT10b and galanin-mediated signaling pathways linked to adipogenesis |
| PMC3362997__F10 | Competitive displacement of DMP1 by ASARM peptide modulates PHEX-DMP1-mediated FGF23 expression (see central osteoblast in green) |
| PMC3363966__F4 | Components and targets of pro-phenol oxidase, Toll-Dorsal/Dif and JAK/STAT pathways |
| PMC3364135__F1 | EpCAM and its potential role in tumor-initiating cells |
| PMC3364461__F1 | Multiple transduction mechanisms induced at the FSHR |
| PMC3364461__F4 | PI3K/mTOR signaling at the FSHR |
| PMC3364790__F4 | Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells |
| PMC3364883__F2 | Protein processing in endoplasmic reticulum is altered in Manf mutants |
| PMC3364883__F4 | Changes in gene expression related to endocytosis in Manf mutants |
| PMC3364883__F5 | Gene expression alterations in Manf mutants with a linkage to Parkinson's disease |
| PMC3364930__F5 | Subcellular localization of components of the PIWI-piRNA pathway and the proposed mechanism of TE suppression by this pathway |
| PMC3364993__F5 | Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes |
| PMC3365480__F1 | Pro- and anti-inflammatory effects of heat and heat shock proteins |
| PMC3365728__F9 | RANKL-induced actin ring organization in mature OCs |
| PMC3365794__F2 | Model showing arterial, venous, and lymphatic cell fate specification in the developing embryos |
| PMC3365799__F13 | Major steroidogenic pathways in the three zones of the human adrenal cortex |
| PMC3365812__F1 | Wnt/Beta-Catenin signaling pathway and their inhibitors |
| PMC3365812__F3 | Hh signaling pathway and their inhibitors |
| PMC3365841__F11 | Pituitary cells express GPCRs that engage the cAMP signaling pathway |
| PMC3365841__F16 | GPCR-modulated channel activity in pituitary cells |
| PMC3365861__F6 | Opposing roles of Myd88 and RAGE in extensive liver resection |
| PMC3366009__F8 | T cell signaling pathway used by A2 and A9 |
| PMC3366012__F2 | TNIP1-mediated signaling pathways |
| PMC3366440__F1 | Protective and pathogenic functions of Th17 cells |
| PMC3366472__F2 | TLR-4 signaling in cancer |
| PMC3366822__F7 | Schematic diagram showing the role of NDRG1 in inhibiting the EMT via regulation of the TGFB/SMAD and Wnt pathways |
| PMC3366852__F5 | Proposed mechanistic link between Por deletion and up-regulation of MHC II expression in enterocytes |
| PMC3366885__F1 | Signaling pathways involved in head and neck cancer |
| PMC3367549__F1 | FGF signaling cascades, an example of RTK signaling |
| PMC3367549__F2 | Canonical (left) and noncanonical (right) WNT signaling pathways |
| PMC3367549__F3 | Sonic hedgehog (SHH) signaling pathway |
| PMC3367549__F4 | BMP signaling pathway and regulation of SMAD activity |
| PMC3367558__F1 | Wnt signaling pathways |
| PMC3367558__F2 | Wnt signaling at vertebrate neuromuscular junctions |
| PMC3367714__F1 | ATM/ATR DNA-damage response pathway |
| PMC3367861__F1 | IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis |
| PMC3367861__F2 | IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis |
| PMC3367865__F3 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367865__F4 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367865__F5 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367865__F6 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367986__F2 | Comparative Genomic Analysis of Soybean Flowering Genes |
| PMC3368076__F6 | Proposed mechanisms of leptin and glucocorticoid stress hormones in the GSK3B/Beta-catenin signaling pathway |
| PMC3368236__F5 | Sema3E-PlexD1 signaling regulates pathway-specific synapse formation in the striatum |
| PMC3368374__F1 | In young muscle, abundant serum IGF-I can stimulate protein synthesis by activating Akt/mTOR/p70S6K pathway |
| PMC3368734__F7 | Functional interaction network analysis of genes with enriched expression (EE) and differential splicing (DS) in the placenta |
| PMC3368902__F1 | Postprandial Regulation of Hepatic MicroRNAs Predicted to Target the Insulin Pathway in Rainbow Trout |
| PMC3368918__F1 | Instrumental Variable Estimation of the Causal Effect of Plasma 25-Hydroxy-Vitamin D on Colorectal Cancer Risk: A Mendelian Randomization Analysis |
| PMC3368988__F2 | Sites of PP2A activity within the network of ERK activation |
| PMC3369606__F2 | Role of DCs in the pathogenesis of GVHD |
| PMC3369817__F8 | Pathway diagram of the cyanobacterial core metabolic network |
| PMC3369892__F8 | Summary diagram of the proposed adrenomedullin (ADM) signaling pathway in the retina |
| PMC3370187__F8 | BMPs and SHH cooperatively provide favorable circumstances for the growth and/or survival of prostate cancer cells and the differentiation of stromal cells |
| PMC3370224__F9 | The ARF6 signaling pathway involved in HLHCGR internalization as deduced from the present study |
| PMC3370283__F2 | Somatic Activating PIK3CA Mutations in CLOVES Syndrome(A) Demonstration of the PIK3CA c.1624G>A somatic mosaic mutation in participant CL4 |
| PMC3370396__F6 | NSAIDs perturbed genes related to thrombosis, fibrinolysis, and PAR signaling |
| PMC3370584__F9 | The regulation of proinflammatory cytokine and chemokine production by MAPKs in THP-1 cells |
| PMC3370605__F1 | Roles of N-acetyl-l-glutamate synthase (NAGS) and of its homologous enzyme N-acetyl-l-glutamate kinase (NAGK) in arginine biosynthesis |
| PMC3370667__F1 | Schema of the FUS1 pathway |
| PMC3371005__F6 | Genome-Wide Association for Sensitivity to Chronic Oxidative Stress in Drosophila melanogaster |
| PMC3371699__F4 | miR-519d, miR-190, and miR-340 in the TGFB signaling pathway |
| PMC3372068__F1 | Coagulation and complement cascades |
| PMC3372214__F1 | Simplified schematic presentation of HCV genotype 2a-mediated blocking of the insulin signaling pathway |
| PMC3372250__F5 | The Hsp90 folding cycle |
| PMC3372318__F3 | The two major signaling cascades operating in cancer, following overactivation of the INSR/IGF-IR signaling pathways |
| PMC3372404__F7 | FUNCTIONAL ACTIVITY OF THE NOVEL ALZHEIMER'S AMYLOID B-PEPTIDE INTERACTING DOMAIN (ABID) IN THE APP AND BACE1 PROMOTER SEQUENCES AND IMPLICATIONS IN ACTIVATING APOPTOTIC GENES AND IN AMYLOIDOGENESIS |
| PMC3372530__F2 | Diagram of genes that have been implicated in susceptibility to CL and ML disease caused by L |
| PMC3372896__F1 | Central role of Beta-catenin in Wnt signaling and the cadherin complex |
| PMC3372896__F3 | Intersection of pathways controlling Wnt/Beta-catenin signaling and cadherin-mediated adhesion |
| PMC3372917__F1 | PTPN11-Associated Mutations in the Heart: Has LEOPARD changed its RASpots? |
| PMC3372922__F2 | Action of TIEG in the TGFBeta-Smad signaling pathway |
| PMC3373577__F4 | Increased Levels of BAFF and APRIL Related to Human Active Pulmonary Tuberculosis |
| PMC3374082__F7 | Schematic representation of the data |
| PMC3374088__F1 | Caspase-8 has a crucial role in the regulation of DRs |
| PMC3374592__F1 | Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles |
| PMC3374768__F11 | Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury |
| PMC3374844__F1 | Three major UPR pathways in metazoans |
| PMC3374856__F3 | Mutations in glutamate signaling pathway and its associated proteins in melanoma |
| PMC3374974__F2 | EphA Receptor Signaling - Complexity and Emerging Themes |
| PMC3375057__F2 | Neurotrophins, the ERK MAP kinase signaling cascade, and GSK-3 |
| PMC3375273__F6 | TRAF-6 Dependent Signaling Pathway Is Essential for TNF-Related Apoptosis-Inducing Ligand (TRAIL) Induces Osteoclast Differentiation |
| PMC3375400__F1 | Comparison of the pathways responsible for the anti-apoptotic and pro-apoptotic effects of immune complexes containing oxidized LDL (oxLDL-IC) and malondialdehyde-modified LDL (MDA-LDL-IC) |
| PMC3375679__F2 | Environmental regulation of GSC proliferation at developmental stages of the gonad |
| PMC3375870__F1 | miR-23a, a critical regulator of "migR"ation and metastasis in colorectal cancer |
| PMC3375988__F7 | Schematic representation of the proposed roles of oleosin |
| PMC3376184__F3 | Function network built upon genes selected from the identified genetic component |
| PMC3376380__F1 | mTOR signaling and its regulation by DGKs |
| PMC3376383__F2 | Growth Control by Committee - Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling |
| PMC3376391__F2 | Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease |
| PMC3376408__F1 | IL-2 release by DCs stimulation of PRRs triggers the calcineurin/NFAT pathway via PLCG2 and intracellular Ca2+ flux |
| PMC3376449__F1 | HER2 signaling pathway |
| PMC3376488__F2 | T-cell development and differentiation |
| PMC3376488__F5 | MyD88 signal pathway |
| PMC3376488__F6 | TRIF signal pathway |
| PMC3376493__F4 | A Human Homeotic Transformation Resulting from Mutations in PLCB4 and GNAI3 Causes Auriculocondylar Syndrome. |
| PMC3376640__F6 | Proposed Model of Psoriasis Pathogenesis in the Presence of Psoriasis-Specific CARD14 AlterationsAfter an inflammatory trigger, alterations in CARD14 induce activation of NF-kB |
| PMC3376735__F1 | Logic of TGFB signalling from the membrane to nucleus |
| PMC3376735__F2 | Regulation of the TGFB-BMP receptor complexes by reversible ubiquitylation |
| PMC3376977__F2 | NK cells sense tumors, course of disease and treatments |
| PMC3377094__F2 | Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins |
| PMC3377280__F7 | Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition |
| PMC3377643__F2 | TGFB and Iron Differently Alter HBV Replication in Human Hepatocytes through TGFB/BMP Signaling and Cellular MicroRNA Expression |
| PMC3377831__F1 | Biosynthesis and catabolism of melatonin |
| PMC3378042__F2 | Implications of Protein Post-translational Modifications in IBD |
| PMC3378544__F4 | Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells |
| PMC3378547__F5 | Molecular Effects of Doxycycline Treatment on Pterygium as Revealed by Massive Transcriptome Sequencing |
| PMC3378977__F1 | Summary of the suggested mechanism for the regulation of MMPs and TIMPs in the paracrine interplay between SCC-25 cells and fibroblasts |
| PMC3379693__F1 | Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut |
| PMC3379801__F8 | p16-Cdk4-Rb signaling pathway diagram |
| PMC3379883__F2 | Leptin and the CNS Control of Glucose Metabolism |
| PMC3380091__F3 | Endometrial androgen target gene set |
| PMC3380218__F1 | The Drosophila IMD and mammalian TNF signalling pathways |
| PMC3380339__F1 | Cross-regulation between the IL-1B/IL-18 processing inflammasome and other inflammatory cytokines |
| PMC3380376__F3 | Relationship between binding of ligands to the pattern recognition AGE receptor (RAGE) and inflammation, gene expression, oxidative and nitrosative stress, and damage to the macro- and microvasculature |
| PMC3380518__F1 | IL-33 signalling pathways |
| PMC3380573__F1 | Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment |
| PMC3380732__F7 | Analysis of the cell cycle pathway |
| PMC3381108__F2 | Unfolded protein response (UPR) |
| PMC3381230__F2 | Major mechanisms of immune modulation by tolerogenic DCs |
| PMC3381238__F1 | Schematic representation of APP processing and role of its products in AD pathology |
| PMC3381650__F3 | Signaling Networks of the Herpesvirus Entry Mediator (TNFRSF14) in Immune Regulation |
| PMC3381865__F6 | Proposed model for the role of the IGF-1R/NFKB signaling pathway in regulating the caspase-3 differentiation initiation signal |
| PMC3381938__F5 | Alternative Macrophage Activation and Metabolism |
| PMC3381956__F1 | Signaling pathways and their targeted therapies in NSCLC |
| PMC3382127__F7 | Toll-Like Receptor 3 and Suppressor of Cytokine Signaling Proteins Regulate CXCR4 and CXCR7 Expression in Bone Marrow-Derived Human Multipotent Stromal Cells |
| PMC3382204__F5 | Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease |
| PMC3382204__F6 | Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease |
| PMC3382204__F7 | Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease |
| PMC3382223__F2 | Ingenuity Pathway Analysis of altered expression of proinflammatory genes in normal human melanocytes |
| PMC3382223__F3 | Ingenuity Pathway Analysis of altered expression of proinflammatory genes in normal human melanocytes transduced with Ad-Slug |
| PMC3382229__F4 | Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis |
| PMC3382229__F5 | Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis |
| PMC3382253__F3 | Mitochondria are central organelles in determining cell fate in liver diseases |
| PMC3382253__F4 | Mitochondria biogenesis allows tissue adaption under stress |
| PMC3382265__F1 | Molecular network of protein degradation, amino acid metabolism, and behavior for NC-treated cells in comparison with TC extract-treated cells |
| PMC3382313__F1 | The role of Notch ligands in our models |
| PMC3382482__F1 | GFPT1-mediated MTOR signaling pathway affected by glucose and fructose in a pTr cell line |
| PMC3382540__F1 | ERK signaling pathway controls T-cell activation and anergy |
| PMC3382911__F1 | Colon cancer cells produce immunoregulatory glucocorticoids |
| PMC3382968__F1 | The four principal manifestations of immunological autophagy |
| PMC3383194__F7 | The mechanism through which PTPN22 blocks proapoptotic and enhances antiapoptotic BCR signals |
| PMC3383335__F1 | SnoN Signaling in Proliferating Cells and Postmitotic Neurons |
| PMC3383335__F2 | SnoN Signaling in Proliferating Cells and Postmitotic Neurons |
| PMC3383648__F1 | ismodegi |
| PMC3383804__F5 | HCMV management of the PI3K/AKT/mTOR pathway |
| PMC3383846__F2 | Signaling pathways that regulate cytokine AREs post-transcriptionally |
| PMC3383919__F1 | Schematic model of the Hippo signaling cascade in mammals |
| PMC3384380__F2 | Schematic depiction of NFKB signaling pathway highlighting FOXP1 target genes |
| PMC3384423__F1 | MTOR signaling pathway |
| PMC3384423__F4 | CRLs/SCF E3 ubiquitin ligases regulate mTOR pathway |
| PMC3384424__F1 | The mTOR signaling pathway |
| PMC3384717__F9 | Androgens up-regulating PCa cell proliferation via p66Shc-ROS signal pathway |
| PMC3385714__F3 | Paralvinella conceptual glutathione pathway and responses to thermal exposure |
| PMC3385949__F1 | FOXO proteins are involved in multiple signaling pathways that control cell proliferation, apoptosis, survival, and immune functions in response to external and internal stimuli |
| PMC3385961__F1 | Evolution of Wnt pathways |
| PMC3385990__F3 | Gp130 mediated IL-6 family of cytokines signaling pathway |
| PMC3386226__F8 | Rad4TopBP1 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner |
| PMC3386270__F8 | IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro |
| PMC3386525__F3 | The signalling transduction pathways involving the tuberous sclerosis proteins, hamartin and tuberin |
| PMC3386543__F7 | Schematic of C/EBP A/B functions in GCs |
| PMC3386597__F3 | AML Signalisome |
| PMC3386597__F4 | AhR-related signaling molecules are enriched within the AML Signalisome |
| PMC3387006__F7 | miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes |
| PMC3387006__F8 | miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes |
| PMC3387019__F7 | Cardiac Kallikrein-Kinin System Is Upregulated in Chronic Volume Overload and Mediates an Inflammatory Induced Collagen Loss |
| PMC3387493__F1 | Dual Aspects of Altered Bone Remodeling in Psoriatic Arthritis |
| PMC3387494__F3 | The regulatory network of EZH2 |
| PMC3387579__F1 | De novo DAG/TAG synthesis (Kennedy pathway) |
| PMC3387654__F1 | Mammalian Hippo pathway and cancer |
| PMC3387977__F3 | Targets for inhibition within the EGFR signaling pathway |
| PMC3388569__F2 | Shared biological pathway activation between chemotherapeutic agent treatments |
| PMC3388569__F3 | Common biological pathways activated in OVCA cells in response to chemotherapeutic agents |
| PMC3388714__F2 | Layers of DC-mediated tolerance |
| PMC3388731__F5 | Canonical Hedgehog signaling |
| PMC3389016__F3 | Anti-Obesity Sodium Tungstate Treatment Triggers Axonal and Glial Plasticity in Hypothalamic Feeding Centers |
| PMC3389182__F1 | Transcriptome analysis of HeLa cells response to Brucella melitensis infection: A molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis |
| PMC3389589__F1 | Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target |
| PMC3390194__F1 | Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer |
| PMC3390208__F8 | Signaling pathway involving CaMKK regulation of GluA1 synthesis and synaptic incorporation as CP-AMPARs |
| PMC3390254__F1 | An emerging role of mTOR in lipid biosynthesis |
| PMC3390257__F2 | mTOR: from growth signal integration to cancer, diabetes and ageing |
| PMC3390419__F1 | Caspases and Kinases in a Death Grip |
| PMC3390457__F1 | Neuroprotective signaling pathways employed by Erythropoietin |
| PMC3390502__F8 | Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells. |
| PMC3390632__F1 | Overexpression of the Coq8 Kinase in Saccharomyces cerevisiae coq Null Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q6 Biosynthetic Pathway |
| PMC3390960__F1 | Formation of the COPII vesicle on the surface of the endoplasmic reticulum |
| PMC3390969__F2 | Impact of a negative regulator on pathogenesis and the development of sepsis, secondary to acute insults |
| PMC3391249__F8 | Defence Signalling Triggered by Flg22 and Harpin Is Integrated into a Different Stilbene Output in Vitis Cells |
| PMC3391329__F3 | Proteome coverage of the KEGG 'Insulin Signaling' pathway |
| PMC3391582__F2 | Signaling Circuitries Controlling Stem Cell Fate: To Be or Not To Be |
| PMC3391966__F1 | Model of hedgehog action in the fetal male reproductive system |
| PMC3392028__F1 | Transcription factors and signaling involved in the osteoblast differentiation pathway |
| PMC3392028__F3 | Seven important signaling networks of osteoblast differentiation |
| PMC3392049__F3 | An example pathway |
| PMC3392150__F1 | Unfolded protein response and its role in intestinal homeostasis and inflammation |
| PMC3392173__F1 | Wnt signaling pathways |
| PMC3392447__F2 | Routes of AMPAR trafficking |
| PMC3392647__F3 | Metabolic regulation of epigenetics |
| PMC3392648__F1 | Insulin signaling pathways |
| PMC3392816__F5 | Model for inhibitory effect of extracellular nicotinamide phosphoribosyltransferase on insulin-like growth factor-1 function in chondrocytes |
| PMC3393131__F1 | Wnt/Beta-catenin signaling in T cell immunity and cancer immunotherapy |
| PMC3393470__F1 | Chemical structures of PSI-352938 and its potential metabolites and the proposed metabolic pathway of PSI-352938 activation |
| PMC3393662__F8 | Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following FcERI Aggregation |
| PMC3393821__F2 | Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: Preliminary findings |
| PMC3393825__F1 | Signaling the Mitochondrial Unfolded Protein Response |
| PMC3394120__F4 | Cytoskeleton remodeling signaling, an example of a differentially regulated pathway in the motor cortex of SALS |
| PMC3394417__F1 | Sample gene regulatory network |
| PMC3394505__F9 | Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas |
| PMC3394800__F4 | Developmental Changes in the Metabolic Network of Snapdragon Flowers |
| PMC3394800__F5 | Developmental Changes in the Metabolic Network of Snapdragon Flowers |
| PMC3394800__F7 | Developmental Changes in the Metabolic Network of Snapdragon Flowers |
| PMC3394947__F1 | The proteins involved in the different pathways related to eicosanoid biosynthesis |
| PMC3394958__F6 | Schematic showing observed protein level alterations in VSCC proteome in the context of HPV infection |
| PMC3395153__F1 | Roles of Platelets and the Signal Transductions Identified as the Major Cascades in Hepatocyte Proliferation |
| PMC3395311__F5 | Integrated view of the role of SUMO in the Ran Signalling pathway |
| PMC3395736__F1 | Glycolytic pathway and its metabolic interconnection with the pentose-phosphate pathway |
| PMC3395887__F3 | Interaction of pathogen recognition and ST2 receptor systems with FcERI leads to substantial enhancement of production of cytokines and chemokines |
| PMC3395995__F1 | Alloantigen presentation via the direct, semi-direct and indirect pathways following organ transplantation, and (B) the relative intensity of each antigen-presentation pathway during the post-transplantation (post-Tx) period |
| PMC3396054__F3 | TGFB activates Smad 2/3 and Smad1 pathway |
| PMC3396155__F5 | The balance in signalling through either ALK-1 or ALK-5 regulates leptin expression in MSC |
| PMC3397239__F2 | Anaplasma phagocytophilum: deceptively simple or simply deceptive? |
| PMC3397358__F1 | Viral genes and the activation of apoptosis |
| PMC3397482__F4 | Cytoscape is an open-source bioinformatics software platform for visualizing molecular interaction networks and integrating these networks with other state data |
| PMC3397508__F1 | Possible molecular mechanisms of Ngb neuroprotection by modulating cell death/survival signaling pathways |
| PMC3397862__F7 | Schematic representation for the up-regulating mechanism of NSC proliferation by modulating Notch signaling with Lewis X-containing glycans in NSCs |
| PMC3397898__F6 | Signaling pathways that regulate cAMP-mediated WPB exocytosis |
| PMC3398046__F5 | MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Treatment with Steroids and Relationship with mRNA Targets |
| PMC3398118__F1 | Diagram of the pentose phosphate pathway showing substrates and enzymes involved in it |
| PMC3398238__F7 | A ubiquitin-binding protein FAAP20 links RNF8-mediated ubiquitination to the Fanconi anemia DNA Repair network |
| PMC3398464__F1 | Key branches of the insulin signaling cascade |
| PMC3398465__F4 | Systems analysis of salivary gland development and disease |
| PMC3398478__F1 | MAPK Pathways in S |
| PMC3398916__F7 | The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network |
| PMC3399091__F1 | PAK1 Molecular Pathway |
| PMC3399249__F2 | Interactions between cytokine and glucocorticoid receptor (GR) signaling pathways |
| PMC3399380__F2 | IGF-IR signaling pathway |
| PMC3399428__F2 | "Hpo signaling pathway in Mammals and the cross-talk with RASFF1A signaling." Schematic representation of mammalian Hippo kinases cascade and interconnections between Hippo pathway and rassf1a protein signal |
| PMC3399530__F2 | Gene expression alterations in Rocky Mountain elk infected with chronic wasting disease |
| PMC3399969__F5 | State-of-the-science: An update on renal cell carcinoma |
| PMC3400941__F1 | Model depicting PI3K signaling |
| PMC3401455__F2 | Rad51 filament formation and regulation |
| PMC3401519__S1 | Calcium/Calmodulin Stimulates the Autophosphorylation of Elongation Factor 2 Kinase on Thr-348 and Ser-500 to Regulate its Activity and Calcium Dependence |
| PMC3401681__F3 | Mesenchymal stem cells (MSCs) may have both growth inhibitory and stimulatory effects on tumours |
| PMC3401939__F1 | Targeting of oncogenes and miRNAs by retroviruses |
| PMC3401974__F2 | Mammalian target of rapamycin (mTOR) pathway regulates T-cell activation, differentiation and migration |
| PMC3402068__F1 | What Goes On Must Come Off: phosphatases gate-crash the DNA damage response |
| PMC3402097__F4 | Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF |
| PMC3402298__F8 | Control of ATM function by Pdk1-Foxo1 pathway |
| PMC3402428__F16 | (Pro)renin Receptor Triggers Distinct Angiotensin II-Independent Extracellular Matrix Remodeling and Deterioration of Cardiac Function |
| PMC3402511__F4 | Novel MicroRNAs Differentially Expressed during Aging in the Mouse Brain |
| PMC3402681__F1 | Proposed mechanistic model on how SHARPIN regulates TNF-induced NFKB activation through linear ubiquitination-mediated mechanisms |
| PMC3402799__F2 | Networks generated by Ingenuity Pathway Analysis of the expression signature |
| PMC3402802__F9 | Regulation of HCA3-induced ERK1/2 activation in A431 cells |
| PMC3403008__F3 | Regulation of TLS in replication-associated ICL repair |
| PMC3403009__F1 | Classical view of the RB pathway and RB function in mammalian cells |
| PMC3403084__F5 | Necrosis signaling pathways |
| PMC3403107__F8 | The molecular pathway regulating Xenopus lung development |
| PMC3403300__F7 | Identification of the HSPB4/TLR2/NFKB axis in macrophage as a therapeutic target for sterile inflammation of the cornea |
| PMC3403522__F2 | Intracellular HIF-1A regulation pathway in normoxia and hypoxia |
| PMC3403683__F1 | T cell receptor (TCR)-mediated signalling pathway |
| PMC3403823__F1 | TLR-induced corneal inflammation |
| PMC3403928__F4 | Caspase cascade |
| PMC3404043__F3 | Whole Transcriptome Analysis of the Effects of Type I Diabetes on Mouse Oocytes |
| PMC3404158__F2a | Ubiquitination and Phosphorylation in the Regulation of NOD2 signaling and NOD2-mediated Disease |
| PMC3404195__F6 | Proposed regulatory mechanism of ERB in colitis-associated colon cancer |
| PMC3404840__F1 | HIV pathogenesis and T-cell signaling by HIV-1 Nef |
| PMC3404840__F2 | Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef |
| PMC3404846__S1 | Mechanism of the tandem DRA/N-Boc protection proposed in this study based on the known pathway |
| PMC3404876__F2 | Identification of novel metastasis suppressor signaling pathways for breast cancer |
| PMC3405133__F3 | Identification of Pathway Deregulation - Gene Expression Based Analysis of Consistent Signal Transduction |
| PMC3405273__F1 | dsRNA receptor signaling pathways in dsRNA-sensitive and -resistant cells |
| PMC3405333__F10 | ERK/MAPK signaling pathway |
| PMC3405333__F11 | P38 MAPK signaling pathway |
| PMC3405730__F2 | IL-2 signals by activating three principal signaling pathways, the SHC/RAS/MAP kinase pathway, JAK1/JAK3/STAT5 pathway, and PI 3-K/AKT/p70 S6 kinase pathway |
| PMC3405855__F5 | Models of apoptosis-induced proliferation in mammals |
| PMC3405863__F4 | EGFR pathway in Drosophila |
| PMC3405863__F5 | Segmentation clock oscillator |
| PMC3405917__F1 | Wound repair and fibrosis |
| PMC3405917__F4 | EMT in fibrosis |
| PMC3406244__F3 | Thyroid Hormone Receptors and Cancer |
| PMC3406577__F6 | Restoration of cell death by ABT-737 in cancer cells that overexpress Bcl-2 and caspase activity is blocked |
| PMC3406594__F8 | Schematic model showing role of AMPKA1 as an upstream kinase of TAK1 in TLR4-mediated signaling pathway |
| PMC3406727__F1 | Simplified schematic drawing of metabolic pathways in Chlamydomonas reinhardtii (adapted from Ref |
| PMC3406917__F3 | Schematic Diagram of Matrix Protein Import into Peroxisomes.Cytosolic PEX5 and PEX7 recognize their cargo proteins (square and round shapes) via binding of specific targeting sequences, PTS1 and PTS2, respectively |
| PMC3407218__F5 | CXCL12/CXCR4 Axis Triggers the Activation of EGF Receptor and ERK Signaling Pathway in CsA-Induced Proliferation of Human Trophoblast Cells |
| PMC3407375__F3 | MicroRNA Circuits in Transforming Growth FactorB actions and Diabetic Nephropathy |
| PMC3407377__F1 | TGFB signaling via TAK1 pathway: Role in kidney fibrosis |
| PMC3407377__F2 | TGFB signaling via TAK1 pathway: Role in kidney fibrosis |
| PMC3407377__F3 | TGFB signaling via TAK1 pathway: Role in kidney fibrosis |
| PMC3407412__F3 | Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles. |
| PMC3407412__F5 | Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles. |
| PMC3407530__F5 | A simplified model for p80HT targeting the IL-10-Stat3 signaling pathway to promote plasma cell expansion and tumor development |
| PMC3407640__F8 | Summary of pathways with differentially expressed genes comparing sarcomas to MSC in the current study |
| PMC3407651__F1 | STAT3 signalling pathway in ALK+ ALCL |
| PMC3407651__F2 | MEK/ERK signalling pathway in ALK+ ALCL |
| PMC3407651__F3 | PI3K/Akt signalling pathway in ALK+ ALCL |
| PMC3407815__F1 | The interleukin (IL)-12/IL-23/interferon (IFN)G pathway and its role in mycobacterial disease control |
| PMC3408141__F8 | The molecular pathway required for NOD2-dependent autophagy |
| PMC3408193__F9 | Proposed protective pathway by E-LP against glutamate-induced apoptosis in RGCs |
| PMC3408195__F9 | A novel KRAS-initiated pathway leading to the activation of VMP1 in cancer cells |
| PMC3408345__F6 | Glucocorticoid (GC) actions in the airways epithelium |
| PMC3408425__F9 | Systems-level regulation of metabolic genes by Met TFs |
| PMC3408426__F10 | Metabolic genes regulated by the Met TFs |
| PMC3408479__F8 | Endoplasmic Reticulum Stress Stimulates p53 Expression through NFKB Activation |
| PMC3408604__F1 | Cardiac myocyte signaling coupled to phosphodiesterase (PDE) 5 |
| PMC3408695__SF1 | Part of the metabolic pathway of estradiol and the role of various enzymes involved: Estradiol is metabolized into 2-hydroxyestradiol (2-OHE2) and 4-hdroxyestradiol (4-OHE2) by CYP1A1 and CYP1B1 respectively |
| PMC3408740__F1 | Alarmins: awaiting a clinical response |
| PMC3408825__F1 | Autophagy pathway: signaling systems and three proposed membrane sources in autophagosome formation |
| PMC3409287__F3 | ITIM-mediated signaling function of IDO |
| PMC3409438__F2 | Broad receptor antagonism and attenuation of downstream signaling cascades mediated by decorin in tumor cells |
| PMC3409471__F2 | Clinical Implications of Cancer Stem Cell Biology in Hepatocellular Carcinoma |
| PMC3409633__F1 | TLR signaling controls transcription and mRNA half-life |
| PMC3410018__F5 | Immune cell types implied to be involved in celiac disease by pathway analyses |
| PMC3410226__F1 | Insulin signaling pathway |
| PMC3410255__F1 | Regulation of PTEN/PI3K/AKT pathway by microRNAs |
| PMC3410320__F1 | Survival and proliferative effects of Dilong extract on RSC96 Schwann cell |
| PMC3410437__F2 | KEGG pathway of the renin-angiotensin system |
| PMC3410580__F2 | Structure and interacting partners of p62/SQSTM1 |
| PMC3410580__F6 | p62/SQSTM1 acts either as a pro-oncogene or as a tumor suppressor protein |
| PMC3410583__F3 | Pathways of autophagy induction by hypoxia and mutant RAS |
| PMC3410756__F1 | Folate mediated one-carbon cycle |
| PMC3410851__F9 | Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System |
| PMC3411062__F1 | Network pathways analysis of molecules identified in T-cells that are involved in LFA-1/ICAM-1 signaling |
| PMC3411066__F6 | Formation and function of 16:1-PI in the signaling of the lipokine 16:1 in Swiss 3T3 cells |
| PMC3411424__F3 | Binary-relation notation and key molecules of AlzPathway |
| PMC3411757__F1 | Modular Nature of Dendritic Cell Responses to Commensal and Pathogenic Fungi |
| PMC3411810__F6 | BRAFV600E Negatively Regulates the AKT Pathway in Melanoma Cell Lines |
| PMC3411916__F3 | [LM5]Strategies for treatment of traumatic central nervous system (CNS) injuries |
| PMC3411967__F1 | Cell-proliferative signaling pathways in lung tumors |
| PMC3412259__F1 | This diagram of BCR/CD19-initiated signaling shows two key outcomes of PI3K activation |
| PMC3412266__F1 | Atypical PKC signaling pathways leading to lymphocyte activation and/or differentiation |
| PMC3412587__F1 | Ras signaling pathway which is disrupted in juvenile myelomonocytic leukemia (JMML) |
| PMC3412625__F6 | Combination therapy with VELCADE and tPA is neuroprotective in aged rats after stroke and targets miRNA-146a and the toll-like receptor signaling pathway |
| PMC3412720__F3 | JAK-STAT signaling pathway |
| PMC3412720__F4 | AKT signaling pathway |
| PMC3412959__F9 | NP1 level modulation by glucotoxicity in Beta-cells |
| PMC3412960__F4 | Scheme of the Rho signaling canonical pathway identified in Ingenuity Pathway Analysis of the proteins with altered expression in both KO cell lines |
| PMC3412962__F4 | A, Differential expression of proteins involved in glycolysis and TCA cycle |
| PMC3412972__F2 | Proteins and protein isoforms in glycolysis/gluconeogenesis, TCA cycle, pentose phosphate pathway, galactose metabolism, and glutamine metabolism pathways |
| PMC3413017__F1 | Apoptosis and necrosis |
| PMC3413046__F2 | Integrated functional association analysis of protein and genetic interactions on alanine and aspartate |
| PMC3413220__F1 | LCAT functions potentially affecting the pathogenesis of cardiovascular disease |
| PMC3413225__F7 | Model describing the mechanisms of quercetin-induced cholesterol efflux in macrophages |
| PMC3413411__F1 | PI3K-AKT-mTOR signaling pathway |
| PMC3413998__F5 | c-Mpl/TPO signaling pathway |
| PMC3413998__F6 | Canonical Wnt signaling pathway |
| PMC3414384__F1 | Actin cytoskeleton as a sensor and mediator of apoptosis |
| PMC3414427__F3 | Schematic model showing the existence of distinct secretory pathways in pheochromocytoma |
| PMC3414439__F4 | Combinatorial Drug Discovery Using Transcriptional Response Modules. |
| PMC3414447__F6 | n-Butyl Benzyl Phthalate Promotes Breast Cancer Progression by Inducing Expression of Lymphoid Enhancer Factor 1 |
| PMC3414724__F1 | Major components of the PI3K pathway in B cells discussed in this review |
| PMC3414724__F2 | Role of the PI3K pathway in B cell antigen presentation functions |
| PMC3414724__F4 | Alterations in the PI3K pathway in malignant B cells |
| PMC3414727__F1 | AKT/mTOR signaling pathway |
| PMC3414727__F2 | AKT/mTOR signaling and crosstalk with glycolysis and mitochondrial oxidative phosphorylation |
| PMC3414739__F2 | LECA Rabs and their proposed functions |
| PMC3414811__F2 | Two branches of the unfolded protein response |
| PMC3415084__F2 | Impact of placental insufficiency on endocrine responsiveness in fetal myoblasts and myofibers |
| PMC3415277__F6 | Identification of multiple disrupted components in a biological pathway |
| PMC3415586__F2 | Estrogen receptors regulate an inflammatory pathway of dendritic cell differentiation: mechanisms and implications for immunity |
| PMC3415708__F4 | A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer |
| PMC3415708__F5 | Novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer |
| PMC3416387__F5 | Proposed metabolic pathways for central carbon and nitrogen metabolism in Y88 during glucose growth, based on protein identifications (dark gray ovals) and the presence of their corresponding genes in the Y88 genome |
| PMC3416606__F1 | Central carbon metabolism in S |
| PMC3416758__F7 | TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells |
| PMC3416961__F1 | Simplified diagram depicting Ras signaling and crosstalk with PI3 kinase- Akt pathway in leukemia |
| PMC3417062__F7 | Molecular mechanisms underlying PA and histologically anaplastic PA |
| PMC3417165__F1 | PI3K/AKT signaling pathway in Tregs |
| PMC3417165__F2 | Intracellular "tug-of-war" determines T cell fate |
| PMC3417337__F1 | Platinum drug action pathway |
| PMC3417348__F8 | Proposed role of ER calcium underlying early disruptions in synaptic homeostasis at the CA3-CA1 synapse in AD |
| PMC3417373__F4 | Signaling cascades that regulate the intrinsic and extrinsic pathways of apoptosis |
| PMC3417440__F1 | Cell death regulation: Signalling pathways and potential sites for pharmacological intervention |
| PMC3417476__F1 | Cyclic AMP-mediated induction of Treg cells and suppression of effector T cells |
| PMC3417478__F1 | Cyclic AMP elevation leads to induction of the SOCS-3 gene in VECs |
| PMC3418056__F5 | Postulated interactions between 20-HETE and RAS in the vascular endothelium |
| PMC3418323__F2 | Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor |
| PMC3418323__F4 | Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor |
| PMC3418323__F5 | Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor |
| PMC3418550__F1 | Pathways of SMX metabolism, bio-activation and detoxification, and pathway of GSH biosynthesis |
| PMC3418560__F5 | Schematic representation of a case of malignant myeloid disease evolving in four stages along one pathway |
| PMC3418709__F1 | Hepatitis C, Porphyria Cutanea Tarda, and Liver Iron: An Update |
| PMC3418714__F1 | B-cell receptor signaling in CLL |
| PMC3418714__F2 | Integrin signaling in CLL |
| PMC3418714__F3 | Kinase inhibitors in CLL |
| PMC3418731__F3 | Signaling within the JAK-STAT pathway in bovine monocytes and M |
| PMC3418756__F6 | Immune activation in the GBS UTI transcriptome comprises prominent cytokine-cytokine receptor signaling |
| PMC3418847__F6 | Interaction Map for PTMScan Direct: Akt/PI3K pathway reagent |
| PMC3418849__F10 | TrkA signaling pathway |
| PMC3419137__F3 | Targets of the tumor suppressor gene miR-200 in regulation of the epithelial-mesenchymal transition in cancer |
| PMC3419258__F6 | Proposed model of FGF23 signaling in proximal tubular cells |
| PMC3419521__F3 | Global regulatory network model of energy-converting pathways |
| PMC3419619__F8 | Protein kinase CD (PKCD) activation by proteolytic cleavage downstream of tumor necrosis factor (TNF) signaling in dopaminergic neurons |
| PMC3419804__F1 | Autophagy, Myocardial Protection and the Metabolic Syndrome |
| PMC3420349__F1 | P53 signaling pathway: In normal conditions (black arrows), p53 is maintained at very low levels |
| PMC3420817__F6 | 12-LIPOXYGENASE AND THE REGULATION OF HYPOXIA-INDUCIBLE FACTOR IN PROSTATE CANCER CELLS |
| PMC3420877__F8 | Celecoxib and GABA Cooperatively Prevent the Progression of Pancreatic Cancer In Vitro and in Xenograft Models of Stress-Free and Stress-Exposed Mice |
| PMC3420937__F6 | PTEN Negatively Regulates MAPK Signaling during Caenorhabditis elegans Vulval Development |
| PMC3421022__F1 | The prolactin signaling network in NetSlim |
| PMC3421049__F1 | Genomic Variation and Neurohormonal Intervention in Heart Failure |
| PMC3421055__F3 | IMPACT OF ALTERED METHYLATION IN CYTOKINE SIGNALING AND PROTEASOME FUNCTION IN ALCOHOL AND VIRAL-MEDIATED DISEASES |
| PMC3421232__F5 | Network of 25 target genes and their interactive genes involved in regulating apoptosis and autophagy |
| PMC3421730__F6 | The antiviral IFN response in infected THP-1 cells |
| PMC3422444__F1 | AIDing antibody diversity by error-prone mismatch repair |
| PMC3422444__F2 | AIDing antibody diversity by error-prone mismatch repair |
| PMC3422477__F1 | Apoptosis affects cell signaling pathways that control lipid synthesis and energy metabolism |
| PMC3422654__F1 | Genes Associated with Outcomes in the Context of Two Fatty Acid Metabolism Pathways |
| PMC3422784__F5 | Sensing the environment: Regulation of local and global homeostasis by the skin neuroendocrine system |
| PMC3423122__F10 | Transcriptome of genes encoding enzymes and proteins on the lactose synthesis pathway, including GLUT1, HK1, PGM1, UGP2, GALE, GALT, SLC35A2, LALBA, and B4-GALT1, -3, and -5 |
| PMC3423122__F11 | Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans. |
| PMC3423123__F3 | Proposed mechanism for exercise-induced mitochondrial biogenesis via NAD+/NADH metabolism |
| PMC3423339__F7 | BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: Implications for Hereditary Hemorrhagic Telangiectasia Type II |
| PMC3423345__F2 | Early Second Trimester Maternal Plasma Choline and Betaine Are Related to Measures of Early Cognitive Development in Term Infants |
| PMC3423373__F3 | Transcriptional Programs Controlling Perinatal Lung Maturation |
| PMC3423475__F9 | Animal oral and veg1 ectodermal GRN for sea urchin embryogenesis |
| PMC3423502__F6 | Crosstalk between Fgf and Wnt signaling in the zebrafish tailbud |
| PMC3423541__F2 | Biological targets under investigation for treatment of SLE |
| PMC3423785__F2 | Functional analysis of the top-scoring network of AE9a dysregulated genes |
| PMC3423855__F1 | Hepatocellular processing of, and immune modulation by, the precore protein |
| PMC3423951__F1 | The interplay between pituitary hormones and main signaling pathways of the IGF system in thyroid, adrenal and ovary cancers |
| PMC3424007__F1 | Biological association network (BAN) of differentially expressed genes in common between CA and ICC |
| PMC3425429__F1 | Working model depicting some of the multiple signaling pathways that have been reported to modulate cell-cycle activation and/or proliferation in rodent Beta-cells |
| PMC3425519__F2 | Intracellular vascular endothelial growth factor (VEGF) signal transduction pathway |
| PMC3425523__F4 | Genes known to cause kidney cancer and their relationship with the mammalian target of rapamycin signaling pathway |
| PMC3425527__F1 | Hedgehog signalling |
| PMC3425856__F4 | CO prevents inflammatory responses via inhibition of NFKB signaling pathway |
| PMC3425953__F1 | Activity of Wnt canonical signaling pathway in the normal and tumor cells |
| PMC3425953__F2 | The activity of the EGFR/KRAS signaling pathway in normal and tumor cells |
| PMC3425953__F3 | The activity of PI3K signaling pathway in normal and tumor cells |
| PMC3426114__F9 | Two Possible Models Regarding the Role of CDT1 Proteins in Response to DNA Stress.(A) Downregulation of CDT1 upon DNA stress may be promoted by WEE1 and/or SOG1 |
| PMC3426219__F2 | Chondroitin sulfate proteoglycan 4 (CSPG4) Signaling Pathways |
| PMC3426484__F1 | Asparagine N-Glycosylation pathway |
| PMC3426490__F2 | Flow chart showing the genes involved in TLR signaling pathway |
| PMC3426550__F6 | SCS3 and YFT2 Link Transcription of Phospholipid Biosynthetic Genes to ER Stress and the UPR |
| PMC3426783__F4 | IPA network analyses were applied to differentially expressed genes in mouse brain after in vivo ketamine exposure |
| PMC3426818__F5 | MUC5B gene expression is transcriptionally regulated by various mediators and pathways |
| PMC3426835__F5 | Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis |
| PMC3427140__F4 | Cross talk between focal adhesion kinase and cadherins: Role in regulating endothelial barrier function |
| PMC3427155__F2 | Analysis of Differential miRNA Expression in the Duodenum of Escherichia coli F18-Sensitive and -Resistant Weaned Piglets |
| PMC3427211__F3 | Microbes-induced EMT at the crossroad of inflammation and cancer |
| PMC3427262__F1 | Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease |
| PMC3427269__F1 | AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway |
| PMC3427417__F7 | Nicotine-induced A7nAChR/JAK2 pathway in cooperation with nicotine-mediated ERK1/2 activation potentiates STAT3 activation in PC cells |
| PMC3427656__F1 | GH-STAT5 signaling pathway |
| PMC3427704__F1 | AID-associated gene network |
| PMC3427792__F1 | Akt isoforms and glucose homeostasis - the leptin connection |
| PMC3427795__F1 | Interplay between FOXO, TOR, and Akt |
| PMC3427885__F4 | Impact of HCV infection on ILK signaling |
| PMC3428061__F2 | Interface between hemostasis and adaptive immunity |
| PMC3428099__F1 | FAM83A and FAM83B: candidate oncogenes and TKI resistance mediators |
| PMC3428242__F1 | Simplified schematic representation of the mammalian target of rapamycin (mTOR) signaling pathway.Notes: Red, pathway inhibitor; Green, pathway activator; Blue, mTOR complex protein.Abbreviation: NOS, not otherwise specified |
| PMC3428335__F8 | Master Regulators in the Metabolic/Transcriptional Coupling in Breast Carcinomas |
| PMC3428377__F3 | Signaling pathways for estrogen production and action |
| PMC3428657__F1 | The signaling pathway ofGHRregulated by let-7b |
| PMC3428770__F2 | Signalling events activating PKB/Akt and cellular functions regulated by PKB/Akt |
| PMC3428775__F3 | Model depicting effects of Wnt-stabilized Beta-catenin through Tcf proteins in mESCs |
| PMC3429047__F5 | Simplified illustration of the canonical Wnt signaling pathway |
| PMC3429058__F1 | HDL promotes regression |
| PMC3429121__F2 | Metabolic flux through the purine salvage pathway in L |
| PMC3429538__F5 | Highlights from this issue |
| PMC3429540__F1 | Emerging role of autophagy in kidney function, diseases and aging |
| PMC3429544__F8 | Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition |
| PMC3429585__F1 | DKK1 as a novel target for myeloma immunotherapy |
| PMC3429622__F4 | TRBP in the exogenous and endogenous RNAi pathways |
| PMC3429771__F5 | Opposing roles of FGF2 and BMP4 in directing TB formation from epiblast type ES cells and iPS cells and the need to exclude FGF2 from the growth medium to minimize the co-induction of mesoderm and endoderm |
| PMC3429879__F1 | Therapeutic Mechanisms of Treatment in Cervical and Vaginal Cancer |
| PMC3429940__F1 | Optimizing treatments for lymphangioleiomyomatosis |
| PMC3430113__F4 | Schematic depicting a central role for transforming growth factor (TGF)B1 signaling in osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis (LCH) |
| PMC3430120__F2 | Summary of pathways controlling muscle protein synthesis (MPS) and muscle protein breakdown (MPB) |
| PMC3430207__F3 | Molecular relational network of genes modulated by BaP in lung tissues enriched for cancer function using IPA for all three doses with p53 at the central node |
| PMC3430210__F1 | TRAIL signaling pathway and mechanisms of TRAIL resistance |
| PMC3430392__F1 | The function of CETP in RCT.Notes: CETP mediates the equimolar transfer of CE and TG between atherogenic VLDL, LDL, and anti-atherogenic HDL |
| PMC3430547__F4 | TORC1 and nitrogen regulation |
| PMC3430718__F7 | SOCS1 regulates the IFN but not NFKB pathway in TLR-stimulated human monocytes and macrophages |
| PMC3430731__F1 | Signaling pathways regulating lipogenesis in cancer cells |
| PMC3430835__F1 | Schematic representation of the potential links between diabetes, glucose metabolites, and pro-inflammatory effects in macrophages |
| PMC3431075__F1 | NFKB members and NFKB signaling |
| PMC3431500__F1 | Class I PI3K signal transduction pathway |
| PMC3431627__F7 | Mechanisms of acquired-resistance to vemurafenib |
| PMC3431702__F7 | TLR signaling and proposed model for DMF-mediated impairment of DC maturation |
| PMC3431883__F3 | Signaling mechanisms of oligodendrocyte injury |
| PMC3432059__F6 | Establishment of Mouse Teratocarcinomas Stem Cells Line and Screening Genes Responsible for Malignancy |
| PMC3432093__F11 | Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells |
| PMC3432190__F2 | Concept of molecular network in schizophrenia |
| PMC3432194__F2 | Epistasis network for WTCCC GWAS of bipolar disorder |
| PMC3432272__F1 | HIV's double strike at the brain. |
| PMC3432348__F1 | Pathways activating and inhibiting complement |
| PMC3432498__F1 | Activation of the IKK-NFKB pathway by radiotherapy and chemotherapy |
| PMC3432564__F2 | Transmembrane CLRs involved in antifungal immunity and their intracellular signaling pathways |
| PMC3432650__F1 | How does Lin28 let-7 control development and disease? |
| PMC3432651__F2 | Involvement of the target of rapamycin (mTOR) pathway in human disease syndromes |
| PMC3432767__F1 | Rac and RhoA signaling pathways during cytokinesis |
| PMC3432834__F2 | Two NFKB activation pathways induced by RANK, CD40, and LtB R signaling |
| PMC3433406__F5 | Large scale phosphoproteome analysis of LNCaP human prostate cancer cells |
| PMC3433899__F3 | Single gene and protein network generated by Approach 3 (Network 1) that demonstrated significance as a clinical relapse predictor following a stringent permutation based test |
| PMC3433902__F5 | Immune response to phagosome in antigen presentation network pathway map associated with the proteins identified as differentially regulated during zebrafish caudal fin regeneration |
| PMC3433910__F1 | Putative scheme of the cellular metabolism in the hydrogen producing arachaeon T |
| PMC3433920__F4 | Acute phase canonical pathway and corresponding acute phase reactants identified as significant for interaction effect |
| PMC3433932__F3 | The scheme summarizes the stretch-induced pathway that allows ROS scavenging in response to mechanical stimuli |
| PMC3434202__F1 | Suppression of Cancer Progression by MGAT1 shRNA Knockdown |
| PMC3434281__F6 | Proposed model for attenuation of canonical TGFB SMAD and activation of non-canonical TGF-Beta-NFKB signaling pathways in HNSCC |
| PMC3434350__F1 | Translational impact of the mTOR signaling pathway |
| PMC3434475__F1 | The canonical translation pathway in eukaryotes with the ribosomal recycling and initiation phases shown in detail |
| PMC3434621__F5 | Interactions of Rex with host pathways, uncovered and covered |
| PMC3434988__F1 | Hepatocyte growth factor (HGF)-cMET axis signaling network and ongoing targeted therapy strategies |
| PMC3435458__F7 | RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells |
| PMC3435478__F2 | Age-related alterations in receptors and signaling molecules of CD8 T cells |
| PMC3436147__F8 | Putative mechanisms of the effect of the Kv1 |
| PMC3436188__F8 | Interaction between Ryk and Wnt signaling pathways |
| PMC3436227__F2 | MyD-88 dependent TLR signaling pathway |
| PMC3436276__F7 | Model illustrates proposed two pathways of regulation of S100A4 mediated by HBXIP |
| PMC3436686__F6 | Ensemble representation of EGF signalling network |
| PMC3436816__F2 | EnrichNet: network-based gene set enrichment analysis. |
| PMC3436837__F1 | Boolean network model of the HGF-induced keratinocyte migration |
| PMC3437205__F3 | Pathway analysis of the hypermethylated genes in lymph node metastasis including their biological processes and association to breast carcinogenesis and neoplasm metastasis |
| PMC3437319__F2 | Regulation of mammalian target of rapamycin complex (mTORC) signaling networks |
| PMC3437536__F1 | Class I phosphoinositide-3-kinase (PI3K) signaling pathway |
| PMC3437546__F2 | HIF target genes encode proteins involved in critical aspects of cancer progression |
| PMC3437636__F2 | Formation of the NFKB-stimulating TNFR1 signaling complex |
| PMC3437743__F1 | Glutathione and modulation of cell apoptosis |
| PMC3437941__F1 | Integration of B cell responses through Toll-like receptors and antigen receptors |
| PMC3437946__F8 | Synthesis and degradation of dopamine, norepinephrine, and serotonin |
| PMC3438135__F1 | Altered pancreatic beta cell mechanism silencing alpha and delta cells |
| PMC3438185__F9 | Novel Levamisole Derivative Induces Extrinsic Pathway of Apoptosis in Cancer Cells and Inhibits Tumor Progression in Mice |
| PMC3438338__F7 | Interferon-Gamma-induced glial cell activation by transforming growth factor B1: A role for STAT1 and MAPK pathways |
| PMC3438361__F2 | Illustration of the metabolic pathway analysis for zidovudine with thick arrows indicating targets identified by the automatic classifier |
| PMC3438665__F1 | p53-dependent and -independent therapeutic strategies for cancer cells |
| PMC3438932__F7 | The role of dimeric TIR platform for the inhibition and activation of MyD88 signaling pathway |
| PMC3439136__F2 | TAP-MS PPI RTK-Ras-ERK signaling network |
| PMC3439136__F3 | Additional analysis of the PPI network |
| PMC3439136__F4 | Dynamics in the RTK-Ras-ERK signaling network |
| PMC3439334__F5 | WNT signalling pathway map enriched with genes up-regulated in tumorgraft-forming tumors |
| PMC3439334__F6 | Immune response pathway map enriched with genes down-regulated in the tumorgraft forming patient tumors |
| PMC3439567__F2 | P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation |
| PMC3439646__F1 | Complement and dysbiosis in periodontal disease |
| PMC3439829__F4 | Diverse cohesinopathy phenotypes |
| PMC3439854__F2 | Transcriptional regulation of PDPN expression |
| PMC3439965__F3 | Simplified overview of the canonical Wnt signaling pathway |
| PMC3440207__F8 | Models for the proposed function of PFT1 in light signaling during photomorphogenic seedling development and the regulation of flowering |
| PMC3440220__F2 | E3 ligases involved in signaling |
| PMC3440368__F7 | Disturbed Relaxin Signaling Pathway and Testicular Dysfunction in Mouse Offspring upon Maternal Exposure to Simazine |
| PMC3440872__F4 | Model showing a role for Yap in governing cardiac growth and survival by interlinking the Hippo, IGF, and Wnt pathways |
| PMC3441384__F4 | Nanoparticle-induced autophagy |
| PMC3441782__F6 | Molecular network of downregulated genes in U373MG cells following exposure to ET-770, the compound 1a |
| PMC3441782__F7 | Molecular network of upregulated genes in U373MG cells following exposure to ET-770 derivative, the compound 3 |
| PMC3442422__F1 | The Sre1 regulatory pathway |
| PMC3442575__F4 | Genes Involved in the Calvin Cycle and Photorespiration.(A) Schematic of the Calvin cycle and photorespiration pathway in C |
| PMC3442742__F1 | NGF signaling pathways in mediating neurotrophic and nociceptor effects.Notes: NGF signals through the high-affinity TrkA and low p75NTR receptors |
| PMC3442804__F2 | Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter |
| PMC3442837__F1 | Regulation of phenotypic transitions in the fungal pathogen Candida albicans |
| PMC3442876__F2 | Autophagy in immunity |
| PMC3442893__F1 | Proline dehydrogenase (oxidase), a mitochondrial tumor suppressor, and autophagy under the hypoxia microenvironment |
| PMC3442981__F1 | Metabolic pathways for 2,3-butanediol biosynthesis and pyruvate metabolism in S |
| PMC3443126__F7 | H2O2-modulated permeability increase and cytoskeleton reorganization via MARCKS phosphorylation in endothelial cells |
| PMC3443185__F1 | Two mechanisms underlying circadian control of NFKB response |
| PMC3443208__F4 | Prenatal Exposure to TCDD Triggers Significant Modulation of microRNA Expression Profile in the Thymus That Affects Consequent Gene Expression |
| PMC3443512__F8 | TARGETING THE eIF4A RNA HELICASE BLOCKS TRANSLATION OF THE MUC1-C ONCOPROTEIN |
| PMC3443855__F7 | Nodal Signaling via an Autocrine Pathway Promotes Proliferation of Mouse Spermatogonial Stem/Progenitor Cells through Smad2/3 and Oct-4 Activation |
| PMC3443857__F1 | Progesterone regulated paracrine signaling model depicted within the uterine compartments at the time of embryo implantation |
| PMC3443885__F3 | Molecular interaction between estrogen and thyroid hormone |
| PMC3444139__F3 | NFKB signaling pathway in ATL |
| PMC3444148__F1 | Nodal signaling pathway in melanoma |
| PMC3444437__F9 | C-srcregulating primordial follicle activation and growth through PI3K →PKC →MAPK signaling pathway |
| PMC3444501__F4 | Therapeutic Effects of Astragaloside IV on Myocardial Injuries: Multi-Target Identification and Network Analysis |
| PMC3444627__F1 | Cytokine Combination Therapy Prediction for Bone Remodeling in Tissue Engineering Based on the Intracellular Signaling Pathway |
| PMC3444692__F2 | ATF-2 is a nuclear target of p38/Jun N-terminal protein kinase (JNK) |
| PMC3444914__F1 | The DNA base excision repair (BER) pathway |
| PMC3445042__F7 | The role of Wnt signaling in hypothalamic progenitor differentiation |
| PMC3445305__F3 | A mitogen-activated protein kinase (MAPK) pathway transduces and integrates intrinsic and environmental signals during stomatal production |
| PMC3445581__F2 | Transcriptional Differences between Rhesus Embryonic Stem Cells Generated from In Vitro and In Vivo Derived Embryos |
| PMC3445623__F2 | Gene Expression and Functional Annotation of the Human Ciliary Body Epithelia |
| PMC3445701__F7 | Alzheimer's Disease pathway from KEGG |
| PMC3445776__F1 | The Hedgehog signaling pathway |
| PMC3446326__F1 | Alterations in the FGFR signalling pathway that influence breast cancer |
| PMC3446495__F1 | Impaired immune system in patients with systemic lupus erythematosus (SLE) |
| PMC3446651__F2 | Viral proteins inhibit nucleic acid receptors of the intracytosolic innate immune response |
| PMC3446895__F5 | Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells |
| PMC3447932__F10 | Vsx2 Controls Eye Organogenesis and Retinal Progenitor Identity Via Homeodomain and Non-Homeodomain Residues Required for High Affinity DNA Binding |
| PMC3448082__F1 | A simplified model of the feeding regulation hypothesis involving the hypothalamic neuropeptide signaling pathway |
| PMC3448443__F2 | Defining the Molecular Nexus of Cancer, Type 2 Diabetes and Cardiovascular Disease |
| PMC3448682__F7 | Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis |
| PMC3448918__F8 | Proposed mechanism for D10G-mediated suppression of NFKB-regulated gene expression |
| PMC3449280__F1 | An engineered eukaryotic protein glycosylation pathway in Escherichia coli |
| PMC3454471__F5 | Redox regulation of the Nrf2-ARE pathway |
| PMC3457170__F4 | JAK/STAT signaling pathway is targeted by RVFV NSs protein at different levels |
| PMC3457296__F8 | LMP2A induces signaling pathways that promote membrane localization of AV-integrin and epithelial migration |
| PMC3457779__F1 | The MAPK cascade activation and potential cross talk signals |
| PMC3457991__F3 | Systematic Analysis of microRNA Targeting Impacted by Small Insertions and Deletions in Human Genome |
| PMC3458056__F5 | Molecular Characteristics and Metastasis Predictor Genes of Triple-Negative Breast Cancer: A Clinical Study of Triple-Negative Breast Carcinomas |
| PMC3458271__F2 | Two proposed models of ephrin-B reverse signaling in palatal EMT based on current evidence |
| PMC3458425__F6 | Docosahexaenoic acid on mouse brain synaptic plasma membrane proteome analyzed by mass spectrometry and 16O/18O labeling |
| PMC3458820__F8 | Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence of Increased 25-Hydroxyvitamin D3 Levels in Male Mice |
| PMC3459232__F6 | PPARG in the pathogenesis of fibrosis |
| PMC3459479__F1 | RAS pathway and its correlation with RASopathies |
| PMC3459659__F1 | Lipopolysaccharide/TLR4 signalling lipopolysaccharide recognition.Notes: Overview of LPS/TLR4 signalling LPS recognition is facilitated by lipopolysaccharide-binding protein and CD14, and is mediated by TLR4/MD-2 receptor complex |
| PMC3460040__F8 | Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with Sorafenib |
| PMC3460045__F3 | Pathological functions of LOX family oxidases during cancer progression and metastasis |
| PMC3460211__F3 | Formaldehyde-responsive miRNAs predicted to modulate MAM-associated genes in the brains of Mgmt-/- mice |
| PMC3460238__F1b | Central role of AP convertase in complement activation |
| PMC3460412__F1 | Activation of p38 MAPK downstrem of TNFR1 |
| PMC3460413__F1 | Mitogen activated protein [MAP] kinase signalling pathways |
| PMC3460904__F7 | Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours |
| PMC3460930__F1 | Lovastatin Induces Multiple Stress Pathways |
| PMC3461086__F3 | Canonical Wnt signaling pathway |
| PMC3461086__F4 | Simplified diagram of signal pathway convergence at downstream nuclear targets |
| PMC3461102__F1 | Cell-Intrinsic Innate Immune Control of West Nile Virus Infection |
| PMC3461213__F1 | Regulatory mechanisms of phosphate homeostasis |
| PMC3461213__F4 | Overall picture of the physiology of FGF-23 and its role in phosphate homeostasis |
| PMC3461241__F3 | Network analysis suggests an immune response and inflammation in ulcerative tissue and non-ulcerative tissue of patients with ulcerative interstitial cystitis (IC) |
| PMC3461607__F1 | LPS/TLR-4 signaling pathway.Notes: LPS is delivered to CD14 by LBP, which in turn transfers LPS to TLR-4 |
| PMC3461631__F2 | Signaling cascades mediated by plexin-A and plexin-B, and their crosstalk with oncogenic pathways in gliomas |
| PMC34619__F2 | Signaling to eukaryotic translation initiation and elongation factors |
| PMC3461903__F2 | New molecular insights into peripheral T cell lymphomas |
| PMC3461905__F2 | Molecular pathogenesis of mantle cell lymphoma |
| PMC3461933__F1 | Looking in the miR-ror: TGFB-mediated activation of NFKB in glioma |
| PMC3461959__F3 | Blastocyst Lineage Segregation and Stem Cells. |
| PMC3462113__F1 | Main metabolic reactions in central carbon metabolism.A) Xylose can be assimilated through two pathways: the fungal oxidoreductive pathway consisting of XR and XDH or the bacterial isomerization pathway via an XI |
| PMC3462343__F7 | Model depicting how chronic exposure to SAg could elicit an autoimmune disease |
| PMC3462655__F2 | The signaling pathways involved in T-cell activation |
| PMC3462935__F5 | Schematic diagram depicting the potential interactions between EGF, S100A11, and Ca2+signaling pathway in human endometrial cell |
| PMC3463457__F1 | Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells |
| PMC3463893__F2 | The inductive and effector sites for the mucosal B-cell response in CD |
| PMC3464048__F1 | Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets |
| PMC3464048__F2 | Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets |
| PMC3464089__F2 | Aberrant activation of the MAPK signaling pathway in papillary thyroid tumor cells |
| PMC3464266__F3 | Insights into Pancreatic Cancer Etiology from Pathway Analysis of Genome-Wide Association Study Data |
| PMC3464294__F4 | Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells |
| PMC3464365__F1 | Linking cellular metabolism with the circadian clock transcriptional complex |
| PMC3464683__F3 | Schematic representation of a plant cell with the major components involved in symbiotic signaling and defense signaling |
| PMC3464734__F2 | Pre-treatment expression of TLR, RIG-I and IFN-beta pathway genes compared between the two patient groups |
| PMC3464875__F7 | Signaling involved in MUC4 expression upon Nicotine, IFNG and Retinoic acid stimulation |
| PMC3465072__F1 | Crowdsourcing Network Inference: The DREAM Predictive Signaling Network Challenge |
| PMC3465249__F3 | Changes in hepatic gene expression in the KEGG PPAR signalling pathway in SNEB compared to MNEB cows |
| PMC3465331__F6 | In Vivo Tumorigenesis Was Observed after Injection of In Vitro Expanded Neural Crest Stem Cells Isolated from Adult Bone Marrow |
| PMC3465335__F4 | Temperature Dependent Proteomic Analysis of Thermotoga maritima |
| PMC3465517__F5 | Network analysis of proteins found to be significantly altered in abundance in the CSF proteome by ANOVA (p value <0.05) following analysis of individual subject samples |
| PMC3466049__F1 | Complement-targeted therapeutics in periodontitis |
| PMC3466241__F7 | Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway |
| PMC3466334__F1 | Genetically-defined metabolic reprogramming in cancer |
| PMC3466334__F3 | Genetically-defined metabolic reprogramming in cancer |
| PMC3466369__F1 | Emerging Roles for Cholesterol and Lipoproteins in Lung Disease |
| PMC3466406__F2 | The integrated large-scale logical model |
| PMC3466406__F7 | Biological insights obtained by combining logical modeling and experimental data |
| PMC3466441__F1 | Peptide neuromodulation in invertebrate model systems |
| PMC3466494__F1 | GSK3 regulates a variety of pathways involved in neurodevelopment |
| PMC3466514__F1 | S6K1 in ER-positive breast cancer |
| PMC3466807__F1 | BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer |
| PMC3466981__F2 | Ubiquitin ligase complexes SCF and APC/C in ubiquitin-mediated proteolysis of regulatory molecules essential for cell cycle control |
| PMC3466981__F3 | The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis |
| PMC3467044__F9 | Model depicting the molecular underpinnings of lamin B2 origin licensing |
| PMC3467356__F1 | Regulatory network analysis of the top genes with SNPs with p<0.001 using MetaCore's shortest pathway algorithm (GeneGo Inc.); the nodes that are circled are the genes of interest |
| PMC3467778__F3 | Skewed Th17/Treg cell differentiation in patients with BD, a hypothesis |
| PMC3468386__F1 | The canonical Wnt signaling pathway |
| PMC3468610__F4 | Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing |
| PMC3469060__F6 | Putative mechanisms responsible for UPR activation by CD147 in human HCC cells |
| PMC3469232__F1 | Cholesterol is converted to pregnenolone by cytochrome P450scc inside steroidogenic mitochondria |
| PMC3469471__F2 | Regulation of the human TRAIL gene |
| PMC3469587__F7 | SP-A-regulated signaling pathways in human macrophages |
| PMC3469596__F8 | Neutral lipid and phospholipid biosynthetic pathways |
| PMC3469602__F4 | Serum and Antibodies of Glaucoma Patients Lead to Changes in the Proteome, Especially Cell Regulatory Proteins, in Retinal Cells |
| PMC3469610__F6 | Schematic diagram of proposed molecular mechanism of p27 downregulation in Fen-induced cell growth in fibroids |
| PMC3469622__F1 | Quantitative Phosphoproteomics Reveals SLP-76 Dependent Regulation of PAG and Src Family Kinases in T Cells |
| PMC3469658__F3 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469658__F4 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469658__F5 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469658__F6 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469673__F1 | Activated CD47 is a proximate regulator of multiple cell survival and cell death pathways |
| PMC3469769__F2 | Multiple roles of COUP-TFII in cancer initiation and progression |
| PMC3469824__F3 | Comparison of mGluR-related signaling pathways activation in successful cognitive aging, Fragile X syndrome, and Alzheimer's disease |
| PMC3470040__F1 | MYCN-dependent apoptosis and the MDM2-p53 pathway |
| PMC3470116__F6 | Simplified schema of putative signaling pathways accountable for the differential responses of A549 (A) and SNB19 (B) cell lines to Hsp90 inhibition and IR |
| PMC3470479__F1 | The Genetics of Alcohol Dependence: Advancing Towards Systems-based Approaches |
| PMC3470584__F2 | Suppressed RNA-Polymerase 1 Pathway Is Associated with Benign Multiple Sclerosis |
| PMC3471227__F1 | Hh pathway activation, inhibition, and mechanisms of drug resistance |
| PMC3471537__F1 | HER2 activation |
| PMC3471537__F4 | General mechanisms of resistance to trastuzumab: presence of upregulation of HER2 downstream signaling pathways |
| PMC3471675__F6 | Structural Insights into the Common Gamma-Chain Family of Cytokines and Receptors from the Interleukin-7 Pathway |
| PMC3471948__F4 | Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos |
| PMC3472459__F5 | Coordinate regulation by NR signaling pathways of genes encoding enzymes in the de novo purine base biosynthesis pathway |
| PMC3472468__F4 | Effects of sleep deprivation on the insulin signaling pathway |
| PMC3472558__F1 | EGFR signaling pathway (reprinted with permission from BioCarta Pathways |
| PMC3472623__F1 | Folate metabolic pathway |
| PMC3472969__F1 | Genotypic-phenotypic model of estrogen metabolism and exposure (yellow box represents genotype component with phenotypic factors outside) |
| PMC3473259__F2 | Main pathway disorders leading to muscle proteolysis, atrophy, hypoxia and anti-oxidant response |
| PMC3474103__F22 | Diagram demonstrating the sites and mechanism of action of novel agents for the management of pancreatic endocrine neoplasm |
| PMC3474186__F3 | Apoptotic signaling through tumor necrosis factor superfamily receptor 6 (Fas) and tumor necrosis factor receptor (TNFR) |
| PMC3474186__F4 | Signaling pathways mediated by rat sarcoma (Ras) and protein kinase B (Akt) |
| PMC3474186__F5 | Role of glutathionylation in the Fas/FasL pathway |
| PMC3474187__F9 | Methionine sulfoxide and methionine sulfoxide reductase (MSR) redox cycle |
| PMC3474235__F1 | The prostaglandin biosynthetic pathway (adapted from []) 15-deoxyÃŽâ€12-14-PGJ2 is a metabolite derived from arachidonic acid |
| PMC3474235__F2 | Scheme of the various interactions between GSTs and MAPK implicated in stress-signaling pathway (adapted from []) |
| PMC3474261__F1 | MTORC1 signaling and genetic mutations at specific sites in the pathway |
| PMC3474280__F1 | Central position of the locus coeruleus in relation to the acoustic startle reflex and pupillary light reflex pathways |
| PMC3474542__F2 | Nongenomic and genomic estrogen signaling pathways |
| PMC3475164__F1 | Biosynthesis of glycerophospholipids |
| PMC3475405__F3 | Blood-brain barrier (BBB) transport in homeostasis of brain AB |
| PMC3475613__F2 | Schematic illustrating metabolic pathways prominent in malignant cells |
| PMC3475760__F1 | As a key downstream target of PI3K-mediated signaling pathway in response to extracellular stimuli such as growth factors through receptor tyrosine kinase (RTK), Akt plays an important role in regulation of diverse cellular processes |
| PMC3475803__F7 | A model depicting ATM- and NEMO-mediated NFKB activation upon accumulation of prelamin A isoforms |
| PMC3476311__F1 | Transmethylation cycle, methyltransferases, points of inhibition by chemical inhibitors, relationship to selenoprotein P, and gluconeogenic enzyme expression as well as downstream physiological effects |
| PMC3476325__F9 | Proposed model for how CCL2 signaling through CCR2 signaling regulates survival and motility of breast cancer cells |
| PMC3476735__F5 | Metformin, an anti-diabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway |
| PMC3477504__F3 | Cytokinesis Mechanics and Mechanosensing. |
| PMC3477860__F1 | STAT1 cycle: signaling pathway and recycling |
| PMC3477860__F4 | Schematic diagrams of the role of STAT1 in antimycobacterial, antiviral and antifungal immunity |
| PMC3478095__F2 | Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease |
| PMC3478260__F4 | signaling pathways triggered by L1CAM |
| PMC3478307__F2 | Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K |
| PMC3478427__F3 | Metabolic Actions of Angiotensin II and Insulin: A Microvascular Endothelial Balancing Act |
| PMC3478445__F12 | Model of Stat3, Ascl1a, and Lin28a in inducing maximal Müller glial proliferation in the light-damaged zebrafish retina |
| PMC3478592__F1 | Model depicts the development of conventional vs |
| PMC3478884__F1 | Emerging role of nuclear architecture in DNA repair and genome maintenance |
| PMC3478886__F1 | Prognostic Value of Cell-Cycle Regulation Biomarkers in Bladder Cancer |
| PMC3479160__F5 | PPI subnetworks of the extended disease pathways |
| PMC3479191__F5 | Multilevel factors cooperatively perturb pathways |
| PMC3479242__F4 | Optimizing the balance between host and environmental survival skills: lessons learned from Listeria monocytogenes |
| PMC3479314__F1 | SHEDDING NEW LIGHT ON NEURODEGENERATIVE DISEASES THROUGH THE MAMMALIAN TARGET OF RAPAMYCIN |
| PMC3479314__F2 | SHEDDING NEW LIGHT ON NEURODEGENERATIVE DISEASES THROUGH THE MAMMALIAN TARGET OF RAPAMYCIN |
| PMC3479319__F1 | Wnt signaling cascadesWnt signals can be transduced either through the canonical pathway (colored in pink) or different non-canonical pathways |
| PMC3479343__F7 | Placental PPARG Regulates Spatiotemporally Diverse Genes And A Unique Metabolic Network |
| PMC3480285__F1 | Metabolic Map of Phenolic Metabolism in the Inflorescence Stem of Arabidopsis.The main pathways involved in lignin biosynthesis are framed with a bold black border |
| PMC3480285__F5 | A Systems Biology View of Responses to Lignin Biosynthesis Perturbations in Arabidopsis. |
| PMC3480380__F8 | Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7 |
| PMC3480485__F5 | Forkhead Box M1 (FoxM1) Gene Is a New STAT3 Transcriptional Factor Target and Is Essential for Proliferation, Survival and DNA Repair of K562 Cell Line |
| PMC3480664__F1 | Neurotrophin Regulation of Energy Balance in the Adult CNS and PNS |
| PMC3480720__F1 | Innate immune signals during B |
| PMC3481038__F2 | Scheme demonstrating mechanisms used by natural compounds to drive changes in the epigenome |
| PMC3481051__F3 | The different main molecular pathways that are involved in neuronal stress response |
| PMC3481134__F7 | PRb/E2F signaling pathway mediates three distinct arms of TGFB tumor-suppressive effects |
| PMC3481284__F8 | Schematic diagram of CaMKII regulates Notch1 signaling through proteasomal degradation of SMRT |
| PMC3481450__F6 | Overlapping network between MCF-7 and ZR-75.1 cells |
| PMC3481480__F11 | Pathway Diagram of Oxidative Stress along with PI3k/Akt |
| PMC3481527__F3 | CB1 cannabinoid receptor signalling and regulation of neural stem/progenitor cell proliferation |
| PMC3481559__F1 | VEGF pathway and its targets for inhibition |
| PMC3481566__F5 | Potential HA signalling pathway mediated by CD44 and TGFB1 receptors |
| PMC3482366__F1 | Summary of folate metabolic pathway |
| PMC3482395__F2 | Canonical biogenesis pathway and mechanisms of miRNA deregulation |
| PMC3482543__F7 | Toll-Like Receptor 2-Mediated Intestinal Injury and Enteric Tumor Necrosis Factor Receptor I Contribute to Liver Fibrosis in Mice |
| PMC3482685__F2 | Regulatory function of TIR8/SIGIRR in signaling |
| PMC3482945__F3 | Pathway related to prostate cancer |
| PMC3483025__F1 | Metabolic pathway of tetrapyrrole biosynthesis in plants |
| PMC3483307__F5 | Novel Genes and Pathways Modulated by Syndecan-1: Implications for the Proliferation and Cell-Cycle Regulation of Malignant Mesothelioma Cells |
| PMC3484225__F1 | Neddylation activates ubiquitination of E3 ligase CRLs |
| PMC3484277__F1 | Downstream signaling of the IGF-1R |
| PMC3484277__F2 | Insulin like growth factor (IGF) and insulin receptor (IR) signaling system |
| PMC3484412__F2 | Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway [] |
| PMC3484421__F2 | The PI3K/Akt/mTOR pathway: Ligands binds to the receptor tyrosine kinases like EGFR, IGF1R, Her2, and Ras leads to conformational changes and activates PI3K |
| PMC3484431__F9 | Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma |
| PMC3484588__F4 | Cellular affects of TNFA.Tumour Necrosis Factor alpha (TNFA) is produced by macrophages, lymphocytes, fibroblasts and keratinocyte |
| PMC3484676__F3 | Rbf1 occupies multiple nodes in conserved signaling pathways |
| PMC3485057__F4 | Increased Biomass Yield of Lactococcus lactis by Reduced Overconsumption of Amino Acids and Increased Catalytic Activities of Enzymes |
| PMC3485747__F1 | Glutamine:fructose-6-phosphate amidotransferase 1 (GFPT1)-mediated MTOR signaling pathway affected by glucose and fructose in porcine trophectoderm cells |
| PMC3486458__F7 | AMPK/ERK/TSC2/mTOR signaling in PCV2-induced autophagy in PK-15 cells |
| PMC3486512__F3 | Network analysis of the host factors found to be associated with the extremities of the murine norovirus genome |
| PMC3488095__F8 | A model for SAHA mediated effects on A1AT folding and trafficking |
| PMC3488108__F1 | Immune-Neuroendocrine Integration at the Adrenal Gland: Cytokine Control of the Adrenomedullary Transcriptome |
| PMC3488210__F3 | Sub-network found among the genes in a differential expression experiment that compares FA patients to controls |
| PMC3488210__F5 | Significant sub-networks (see also ) found among the lists of most essential genes, ranked by the RIGER parameter, obtained for both cell lines: (A) Jurkat and (B) K562 |
| PMC3488564__F7 | Proposed model for the role of TGFB in IL4-induced alternative microglia activation |
| PMC3488630__F2 | Proposed model of HER2/3 signaling in epithelial cells |
| PMC3488811__F1 | Simplified diagram of choline-related one-carbon metabolism |
| PMC3489622__F2 | Signaling networks induced in the spleen at 1 day post infection in wild-type mice (A) and STAT1 KO mice (B) |
| PMC3489746__F2 | Targeting the MHC Class II antigen presentation pathway in cancer immunotherapy |
| PMC3489747__F2 | TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis |
| PMC3489757__F1 | New insights on the role of CD8+CD57+ T-cells in cancer |
| PMC3489783__F3 | Representative KEGG pathway change of Endocytosis |
| PMC3489927__F6 | Characterization of c-Kit expression and activation in KSHV-infected endothelial cells |
| PMC3489928__S4 | Proposed Reaction Pathway |
| PMC3490020__F1 | The main MicroRNA biosynthetic pathway |
| PMC3490280__F2 | Recipient T-lymphocytes govern Mesenchymal stem cell (MSC)-based bone regeneration via IFNG and TNFA |
| PMC3490581__F4 | Illustration of fluxes in central carbon metabolism for metabolic phases II and III along the protein/ tradeoff |
| PMC3490606__F1 | Reactions involved in the flux of fatty acids into |
| PMC3490712__F1 | Mammalian network model |
| PMC3491070__F3a | Cancer Cell Metabolism: One Hallmark, Many Faces |
| PMC3491089__F4 | Schematic representation which shows possible mechanisms of action by D- and Gamma-tocopherol in multiple signaling pathways involved in mammary carcinogenesis |
| PMC3491806__F2 | Inflammatory Bowel Disease |
| PMC3491811__F3 | Calcium regulation of keratinocyte differentiation |
| PMC3491835__F7 | 5-HT6 receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia |
| PMC3491906__F1 | Distinct signaling pathways of synaptic and extrasynaptic NMDAR in neuron fate |
| PMC3491909__F1 | Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR |
| PMC3492042__F3 | MicroRNA targetome suggests aberrant upregulation of cell cycle regulators in AD brains |
| PMC3492042__F5 | MicroRNA targetome suggests aberrant upregulation of T cell receptor signaling pathway molecules in ATL cells |
| PMC3492042__F8 | MicroRNA targetome suggests aberrant upregulation of cell cycle regulators in AD brains |
| PMC3492204__F5 | A simplified scheme to illustrate the dual roles played by KIF7 in Indian Hedgehog (IHh) signaling and chondrocytes development |
| PMC3492208__F3 | Principal IFN-Alpha-modulated canonical pathway in MT-4 cells |
| PMC3492658__F1 | NOD1 and NOD2 signaling pathways and interaction partners |
| PMC3492703__F1 | Biosynthesis and posttranscriptional processing of miRNA |
| PMC3492913__F1 | Diagrammatic representation of BMP signaling pathway |
| PMC3492937__F5 | Stem cell pathways analysis for label-retaining cancer cell (LRCC) |
| PMC3492958__F1 | Distinct roles for AlphaB hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling |
| PMC3493339__F1 | ERBB Pathway |
| PMC3493339__F4 | STRING Network |
| PMC3493385__F2 | RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways |
| PMC3493464__F1 | Functional Analysis of Metabolic Channeling and Regulation in Lignin Biosynthesis: A Computational Approach |
| PMC3493640__F1 | Multi-omic map of the lipid-producing yeast Rhodosporidium toruloides |
| PMC3493824__F1 | Cellular Targeting in Autoimmunity |
| PMC3493824__F2 | Cellular Targeting in Autoimmunity |
| PMC3493873__F1 | TP53 mutation status-specific network of potential candidate driver genes shown based on their known and predicted functional interactions |
| PMC3493902__F8 | The diagram illustrates the possible mechanism of tumor cells-secreted CCN1 in regulation of pancreatic carcinogenesis through the regulation of SHh signaling |
| PMC3493930__F8 | Mechanisms by which AP-1 transcription factor regulates LY6K expression, which activates the ERK signaling pathway to mediate cell invasive motility and metastasis in human breast cancer cells |
| PMC3494084__F4 | Baculovirus infection impact on host cell metabolism |
| PMC3494149__F6 | VANTED integrated pathway map of quantitative regulation of metabolites and enzymes of primary metabolism under nitrogen limitation in Chlamydomonas reinhardtii |
| PMC3494151__F4 | Impact of SIRT1 knockout on selected cellular pathways and protein complexes |
| PMC3494185__F7 | Hypothetical schematic of the roles of KPNA2 and E2F1 in NSCLC |
| PMC3494243__F2 | Pathways for C18 PUFA conversion to C20-22 PUFA synthesis |
| PMC3494373__F7 | Regulation of MDM2 by chronic stress and neurohormones |
| PMC3494587__F12 | Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes |
| PMC3494597__F1 | Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells |
| PMC3494605__F1 | A role for vimentin in Crohn disease |
| PMC3494767__F5 | Synergistic cancer cell death in response to stress when TSC2, but not Pten is inactivated in the context of a deregulated Rb pathway |
| PMC3495118__F1 | Transcriptional regulation of the cytoprotective phase 2 genes under control of the transcriptional factor nuclear factor-E2 p45-related factor 2 (Nrf2) |
| PMC3495133__F1 | Schematic of the desaturation and elongation biosynthetic pathway of essential dietary fatty acids to longer chain fats |
| PMC3495805__F1 | Functional roles of pluripotency transcription factors in mesenchymal stem cells |
| PMC3495983__F6 | Model illustrating CD40-induced signals that mediate the expression of VEGF in endothelial cells |
| PMC3496019__F1 | Cancer Stem Cells |
| PMC3496019__F2 | Regulation of CSCs by inflammatory cytokine networks |
| PMC3496044__F7 | Sialic acid biosynthetic and degradative pathways |
| PMC3496805__F2 | TARGETING THE INTRAGRAFT MICROENVIRONMENT AND THE DEVELOPMENT OF CHRONIC ALLOGRAFT REJECTION |
| PMC3496878__F1 | Signal transduction in solid cancer cells including hepatocellular carcinoma |
| PMC3496878__F4 | Phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signaling pathway in cell proliferation in solid cancer |
| PMC3497051__F4 | Autophagy process |
| PMC3497272__F2 | ErbB signaling and inhibition in tumour cell |
| PMC3497295__F1 | Selected signaling pathways in renal cell carcinoma (RCC) |
| PMC3497822__F7 | The signaling pathway by which FSH promotes AKT activation in GCs |
| PMC3497822__F1 | The signaling pathway by which FSH promotes AKT activation in GCs |
| PMC3498232__F9 | Expression Profile in Rice Panicle: Insights into Heat Response Mechanism at Reproductive Stage |
| PMC3498346__F1 | Impaired Skeletal Muscle Regeneration in the Absence of Fibrosis during Hibernation in 13-Lined Ground Squirrels |
| PMC3498840__F1 | TLR signaling overview: the TLR family can be subdivided into two categories |
| PMC3499024__F2 | Bone anabolism regulated by statins |
| PMC3499061__F2 | Schematic illustrations of the two significant pathways in the genome-wide gene self-reported asbestos exposure interaction analysis |
| PMC3499080__F2 | Alterations in the NRF2 canonical pathway in livers of mice treated with TMHF |
| PMC3499189__F2 | Synopsis of major pathways activating mTORC1 |
| PMC3499189__F3 | Aberrations of PI3K-Akt-mTORC1 signaling pathway in prostate cancer |
| PMC3499531__F6 | Transcriptome Sequencing and Annotation for the Jamaican Fruit Bat (Artibeus jamaicensis) |
| PMC3499662__F1 | Cell-signaling pathways from the UPR to autophagy and ER stress-induced apoptosis |
| PMC3499814__F2 | RIG-I signaling pathway and inhibition by influenza A viruses (Figure adapted from []) |
| PMC3499814__F3 | Type I IFN signaling pathway and inhibition by influenza A viruses (Figure adapted from []) |
| PMC3499881__F1 | Regulation of the polyamines putrescine, spermidine and spermine by biosynthetic enzymes (shown in green) and catabolic enzymes (shown in red) |
| PMC3499976__F1 | Wnt transduction pathways and their functions during synapse development, function and plasticity |
| PMC3499997__F2 | Main therapeutic targets along the BCR signaling pathway in CLL cells |
| PMC3500394__F1 | FoxM1 and Wntβ-catenin Signaling in Glioma Stem Cells. |
| PMC3500439__F1 | Molecular Pathways: The Metabolic Regulator Estrogen-Related Receptor Alpha as a Therapeutic Target in Cancer |
| PMC3500781__F1 | Two different pathways could bypass DNA damage causing stalled replication forks |
| PMC3500850__F4 | Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response |
| PMC3500853__F3 | EphrinB reverse signaling |
| PMC3500863__F3 | Pathways regulating NEKs in cell cycle control |
| PMC3501016__F1 | Finding a New Regulator of the Blood Coagulation Cascade♦ |
| PMC3501082__F7 | A model to depict Tollip cooperating with Smad7 to mediate degradation of the TGFB receptor complex |
| PMC3501207__F1 | Cholesterol Accumulation Regulates the Expression of Macrophage Proteins Implicated In Proteolysis and Complement Activation. |
| PMC3501223__F1 | Role of Esrrb in ESC self-renewal and reprogramming |
| PMC3501616__F4 | Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome wide association on chromosome 1p22 |
| PMC3502106__F5 | Figure 8: Feed-forward signaling in which FGF-9 controls Wnt-2a expression and mesenchymal Wnt/Beta-catenin signaling, and in which mesenchymal Wnt/Beta-catenin signaling is requisite for mesenchymal FGFR expression and mesenchymal responsiveness to FGF-9 |
| PMC3502514__F1 | Activation of stress signalling pathways in the liver of sows during lactation |
| PMC3502626__F7 | A theoretical model of synergistic interactions between resveratrol and HDAC inhibitors is presented |
| PMC3502657__F1 | Signaling pathways for longevity |
| PMC3502657__F2 | Signaling pathways for longevity |
| PMC3502714__F2 | Fibroblast growth factor 23: State of the field and future directions |
| PMC3502714__F3 | Fibroblast growth factor 23: State of the field and future directions |
| PMC3502766__F5 | Proposed metabolic pathway for the degradation of VFA and TCE inferred from the metaproteomic data |
| PMC3502787__F1 | General features of the HER family |
| PMC3502876__F1 | Reactive oxygen species-mediated autophagy regulation |
| PMC3502886__F1 | PI3K/Akt/mTOR pathway regulates central carbon metabolism |
| PMC3503525__F1 | WNTS AND TGFB IN SYNAPTOGENESIS: OLD FRIENDS SIGNALLING AT NEW PLACES |
| PMC3503557__F5 | Network and pathway structure for biologically informative priors in the cancer drug response data study |
| PMC3504253__F1 | Inactivated Wnt pathway |
| PMC3504253__F2 | Activated Wnt pathway |
| PMC3504364__F2 | Methotrexate (MTX) mechanisms of action in the folate metabolic pathway |
| PMC3504424__F4 | Tyrosine kinase receptors pathway |
| PMC3504424__F5 | Transforming growth factorB (TGFB) pathway |
| PMC3504431__F1 | MTOR pathway |
| PMC3504641__F1 | Schema of the cholesterol pathway |
| PMC3504715__F8 | Cytokine-induced CITED2/MYC/E2F3/p21CIP1signaling in lung cancer |
| PMC3504728__F7 | Speculative model of macrophage alternative activation regulation by estrogen |
| PMC3505266__F3 | Heterogeneity in the differentiation and function of memory B cells |
| PMC3506510__F2 | Signaling pathways impinging on autophagy |
| PMC3506908__F4 | Pathway analysis derived by comparison of the relative abundance of metabolites from sera derived from patients with locoregional CRC and liver-only metastases, as determined by GC-MS |
| PMC3507178__F3 | Flow chart depicting the metabolic pathway of fatty acids in the liver of GH transgenic Amago based on 3'-tag digital gene expression profiling and comparison of serum triacylglycerol and glucose, and 3-hydroxybutyric acid |
| PMC3507180__F2 | Hypothetic regulation of gene expression by HNF-4A by spherical cell shape in FLC-4 cells |
| PMC3507272__F1 | Schematic diagram showing the RAS-MAPK signal transduction pathway |
| PMC3507315__F2 | T cell receptor signaling pathway extracted from BioCarta database [] |
| PMC3507315__F3 | Fc epsilon receptor I signaling in mast cell pathway extracted from BioCarta database [] |
| PMC3507315__F9 | mTOR signaling pathway extracted from KEGG database [] |
| PMC3507431__F2 | Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy |
| PMC3507479__F1 | An expanded role of the tumor suppressor TSC1 in T cell tolerance |
| PMC3507808__F1 | Metabolites and their metabolic pathway networks measured by the Arg/Thiol Redox Metabolomics Assay |
| PMC3508164__F12 | Proposed model of Cripto-1 modulation of the Wnt/Beta-catenin signaling pathway |
| PMC3508169__F2 | Known relationships between the candidate genes |
| PMC3508196__F1 | TARGETING ONCOGENIC BRAF IN HUMAN CANCER |
| PMC3508562__F1 | Diagram representing the possible endogenous and exogenous TLR activation pathways and the accompanying response.Abbreviation: TLR, toll-like receptor |
| PMC3508562__F2 | Genomics in cardiovascular diseases: analysis of the importance of the toll-like receptor signaling pathway. |
| PMC3508619__F1 | MYC proteins and the p53/MDM2/p14ARFpathway |
| PMC3509372__F1 | Treg regulatory pathways |
| PMC3509664__F3 | PKR and the Insulin signaling pathway |
| PMC3509664__F7 | HCV and induction of the innate immune response |
| PMC3509664__F8 | PKR, ISG15 as modulators of IFN induction during HCV infection |
| PMC3509680__F3 | Functional roles of the arenavirus Z protein in the viral life cycle |
| PMC3509687__F1 | Impact of the cellular restriction factor APOBEC3 (A3) on human immunodeficiency virus-1 (HIV-1) replication |
| PMC3509712__F1 | Signal transduction pathways used by superantigens and mediators |
| PMC3509860__F1 | Pathway for synthesis and catabolism of dopamine and serotonin |
| PMC3509892__F1 | Transcriptional Changes Associated with Lack of Lipid Synthesis in Parasitoids |
| PMC3509894__F3 | Vitamin B12 Synthesis and Salvage Pathways Were Acquired by Horizontal Gene Transfer to the Thermotogales |
| PMC3510027__F2 | Genome-Scale RNA-Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease |
| PMC3510027__F3 | Genome-Scale RNA-Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease |
| PMC3510514__F6 | Model for the role of Spartan in DNA damage tolerance |
| PMC3511325__F9 | Protective Role of STAT3 in NMDA and Glutamate-Induced Neuronal Death: Negative Regulatory Effect of SOCS3 |
| PMC3511450__F5 | Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways. |
| PMC3512134__F6 | Overall organization of mitotic exit control |
| PMC3512188__F3 | Roles of miRNAs in DNA damage response |
| PMC3512410__F2 | Scheme depicting the different outcomes caused by the presence of progerin and prelamin in cells |
| PMC3512574__F3 | TGFB in Cancer |
| PMC3512574__F5 | TGFB in Cancer |
| PMC3513217__F2 | Schematic illustration of irinotecan disposition pathway |
| PMC3513217__F3 | Metabolism pathway of tamoxifen and its interaction with estrogen receptors.Copyright © 2009 |
| PMC3513219__F2 | XRCC1 is instrumental in base excision repair (BER) of small oxidative lesions and a related mechanism for the repair of single-strand breaks (SSB-R), both caused by ionizing radiation |
| PMC3513309__F3 | Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, InterferonA and Dendritic Cell Vaccine |
| PMC3513309__F4 | Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, InterferonA and Dendritic Cell Vaccine. |
| PMC3513366__F1 | Progastrin Peptides Increase the Risk of Developing Colonic Tumors: Impact on Colonic Stem Cells |
| PMC3513650__F1 | BRCA and RAD52 pathways of DNA double-strand break (DSB) repair |
| PMC3513735__F3 | Most enriched molecular networks showing interactions between the significant genes (according to SAM)–(a) FOSB, ERK, MAPK3, CYR61, and the RAS-genes; (b) DUSP1, ERK1/2, P38MAPK, DUSP9, and RASD1; (c) CYR61 and NFRKB |
| PMC3513881__F3 | Proposed three pathways for the mechanism of nicotinic acetylcholine receptor (nAChR)-mediated survival signal transduction |
| PMC3513983__F3 | Major signaling pathways regulating RSV-induced NFKB and IRF activation in airway epithelial cells |
| PMC3514012__F5 | IPA generates IL-17C interactome |
| PMC3514292__F1 | Schematic representation depicting A; the protein synthesis pathway in skeletal muscle involving the mammalian target of rapamycin complex 1 (mTORC1) |
| PMC3514351__F1 | Ingenuity pathways analysis summary |
| PMC3514454__F7 | Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo |
| PMC3514612__F7 | Synthesis of nitric oxide and transduction cascades |
| PMC3514614__F4 | Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway |
| PMC3514620__F2 | DNA repair pathways and implicated proteins |
| PMC3514635__F4 | Intracellular trafficking proteins involved in CMT neuropathy |
| PMC3514827__F1 | Using components of the Vitamin D pathway to prevent/treat colon cancer |
| PMC3514880__F3 | Genome sequences of wild and domestic bactrian camels |
| PMC3514894__F1 | Interplay between Smoking-induced Genotoxicity and Altered Signaling in Pancreatic Carcinogenesis |
| PMC3514907__F3 | GeneGo "Cell Adhesion_ECM remodeling" pathway map |
| PMC3515033__F2 | Classification of Toll-like receptors (TLRs) |
| PMC3515033__F3 | Classification of nucleotide-binding oligomerization domain proteins (Nods) |
| PMC3515033__F4 | Neural and humoral activation of the brain by the periphery |
| PMC3515033__F5 | Cytokine intracellular signaling pathways |
| PMC3515332__F1 | Class I PI3K/Akt/mTOR axis pathway |
| PMC3515549__F7 | Screening the Budding Yeast Genome Reveals Unique Factors Affecting K2 Toxin Susceptibility |
| PMC3515668__F1 | Schematic representation of the potential disruption of the hepatic GHR-JAK2-STAT5b signal transduction pathway by TCDD |
| PMC3515677__F1 | Summary of the mechanisms of DC-mediated HIV-1 transmission to CD4+ T cells |
| PMC3515828__F8 | Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus |
| PMC3515920__F1 | Retinoid refractoriness due to phosphorylation of retinoid X receptor alpha (RXR A), and its restoration by acyclic retinoid (ACR) in liver carcinogenesis |
| PMC3516044__F3 | Changes in the Plasmodium falciparum redox flux network after MB drug action.Notes: Results incorporating the transcription data and experimental mRNA expression data nine hours after incubation with methylene blue are shown |
| PMC3516599__F1 | Proposed Multicompartmental Degradative Pathway of L-lysineL-Lysine degradation is initiated by either peroxisomal Alpha-deamination (pipecolate pathway) or mitochondrial E-deamination (saccharopine pathway) |
| PMC3516764__F9 | Model for the involvement of the RA in neuronal differentiation |
| PMC3516830__F2 | Interaction loop between the EGFR signaling pathway and miR-221/222 expression in the modulation of cellular processes |
| PMC3517080__F5 | Putative Altered Signaling Events occurring upon treatment of GSI |
| PMC3517092__F1 | Schematic depiction of the role of the retromer complex in mediating endosomal protein sorting |
| PMC3517178__F2 | Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression |
| PMC3517193__F1 | Graphic illustration of the perturbation of the insulin signal transduction pathways by cellular stressors |
| PMC3517549__F1 | The Evolution and Origin of Animal Toll-Like Receptor Signaling Pathway Revealed by Network-Level Molecular Evolutionary Analyses. |
| PMC3517549__F5 | Evolution and Origin of Animal Toll-Like Receptor Signaling Pathway Revealed by Network-Level Molecular Evolutionary Analyses |
| PMC3517581__F7 | Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal SH-SY5Y Cells. |
| PMC3517648__F7 | Cartoon describing differential O2 sensing in EC cells and signal pathway/5-HT secretion |
| PMC3517905__F1 | Summary of the signaling pathways of PKMζ-mediated late-LTP |
| PMC3518132__F8 | Alkylphospholipid (ODPC)-induced raft-based inhibition of cell signaling |
| PMC3518257__F7 | 14-3-3 signaling canonical pathway from IPA |
| PMC3518431__F1 | Autophagy modulation as a potential therapeutic target for diverse diseases |
| PMC3518431__F2 | Autophagy modulation as a potential therapeutic target for diverse diseases |
| PMC3518467__F1 | Fast, Potent Pharmacological Expansion of Endogenous Hes3+/Sox2+ Cells in the Adult Mouse and Rat Hippocampus |
| PMC3518509__F2 | Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway |
| PMC3518543__F4 | NFKB activation pathway is regulated by S-nitrosylation |
| PMC3518557__F1 | Targets and structure of compstatin |
| PMC3518570__F2 | Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease |
| PMC3518582__F1 | Wnt Signal Transduction Pathways |
| PMC3518582__F3 | Wnt7a signals bidirectionally through divergent pathways to influence both presynaptic and postsynaptic assembly and to promote excitatory synapse formation and function |
| PMC3518628__F3 | Interplay between Wnt/Beta-catenin signaling and HIV: Virologic and biologic consequences in the CNS |
| PMC3518872__F3 | Top three networks of significantly associated molecules in TGFB1+LPS+IFNGamma-treated astrocytes |
| PMC3518872__F4 | Three IPA Canonical Signaling Pathways: CD40, IL-1, and Chemokine Signaling in TGFB1+LPS+IFNGamma-treated astrocytes |
| PMC3518872__F6 | GPCR Canonical Signaling Pathways |
| PMC3519537__F1 | Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing |
| PMC3519537__F5 | Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing |
| PMC3519901__F7 | Quantification of the Host Response Proteome after Mammalian Reovirus T1L Infection |
| PMC3519947__F1 | Simplified diagram illustrating the mTOR signaling pathway |
| PMC3519956__F6 | Schematic model depicting how HMW isoforms regulate bone formation |
| PMC3520003__F1 | Simplified summary of the role of ATGL in macrophages.FFAs which are taken up by macrophages are incorporated into TGs (and cholesteryl esters) |
| PMC3520045__F4 | Summary diagram of Nrf2 and HIF1 stimulation in presence of oxidative stress |
| PMC3520048__F2 | Summary of the role of the mammalian target of rapamycin (mTOR) signaling pathway in the development of tuberous sclerosis complex (TSC) and inhibition by mTOR inhibitors |
| PMC3520539__F1 | Generalized overview of the regulation of apoptosis by sphingolipids |
| PMC3520542__F13 | Molecular mechanism for Elovl5 control of mTORC2, FoxO1-S256 phosphorylation, and hepatic GNG |
| PMC3520610__F1 | Targeting the TGFB signalling pathway in disease |
| PMC3520610__F2 | Targeting the TGFB signalling pathway in disease |
| PMC3520610__F5 | Targeting the TGFB signalling pathway in disease |
| PMC3520613__F5 | Macrophage VLDL Receptor Promotes PAFAH Secretion in Mother's Milk and Suppresses Systemic Inflammation in Nursing Neonates |
| PMC3520616__F1 | Upstream events in BCR signaling |
| PMC3520885__F2 | R(h)oads to microvesicles |
| PMC3520888__F1 | Escorting Ras |
| PMC3521040__F2 | Molecular mechanisms of activation, amplification, regulation, and evasion of the AP C3 convertase |
| PMC3521191__F1 | Biological pathways targeted for therapy in renal cell carcinoma based on a knowledge of the underlying genetic changes and downstream biological consequences |
| PMC3521201__F1 | Central carbon metabolism pathways in E |
| PMC3521387__F7 | ILOCi detected genes from BD and their maps in 'neuroactive ligand-receptor interaction' pathway |
| PMC3521387__F8 | ILOCi detected genes from CAD and their maps in 'cytokine-cytokine receptor interaction' pathway |
| PMC3521387__F9 | ILOCi detected genes from T1D and their maps in 'type I diabetes mellitus' pathway |
| PMC3521791__F6 | Part of the top canonical pathway affected by in vivo LPS administration into the human lung |
| PMC3522553__F1 | Components of the Hedgehog (Hh) Signaling Pathway and molecular sites targeted by Hh pathway inhibitors |
| PMC3522801__F1 | DNA Damage Signaling Assessed in Individual Cells in Relation to the Cell Cycle Phase and Induction of Apoptosis |
| PMC3522801__F2 | DNA Damage Signaling Assessed in Individual Cells in Relation to the Cell Cycle Phase and Induction of Apoptosis |
| PMC3522877__F8 | TGFB3 in two human skin cell types critical for wound healing |
| PMC3523093__F1 | Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches |
| PMC3523565__F1 | Simplified scheme of the mitogen-activated protein kinase (MAPK) (RAS-RAF-MEK-ERK) signaling pathway.Notes:BRAF and NRAS are the most commonly mutated oncogenes in melanoma |
| PMC3523725__F7 | PPARG COUNTERACTS LRP1-INDUCED VASCULAR CALCIFICATION BY INHIBITING A WNT5A SIGNALING PATHWAY |
| PMC3523822__F1 | Biosynthetic pathway of diphthamide in eukaryotes |
| PMC3524013__F3 | Full network comparison of the original canonical pathway and the inferred cell-type-specific pathway |
| PMC3524085__F7 | Ingenuity pathway analysis of the 10-edge pattern subgraph showing cancer-associated interactions among its nodes |
| PMC3524152__F2 | Bacterial effector targets the TRAF6-NFKB pathway to modulate the acute inflammatory response to bacterial invasion of epithelial cells |
| PMC3524155__F1 | Sensing the enemy |
| PMC3524194__F1 | Upstream regulators of the Hippo pathway |
| PMC3524227__F1 | Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells |
| PMC3524319__F6 | Construction of the regulatory networks associated with the selected genes using IPA® database |
| PMC3524627__F8 | Model depicting the regulation of DNA damage-induced germ cell apoptosis by C |
| PMC3524689__F2 | Proposed model of OGP(10-14) differentiation signalling |
| PMC3524696__F1 | Schematic diagram represents the ischemic preconditioning pathway in cardiomyocytes |
| PMC3525110__F3 | Proposed model for EA signaling |
| PMC3525180__F3 | Some perifosine-specific genes are connected by common pathways leading to MAPK signalling pathway and apoptosis |
| PMC3525581__F7 | Toxicogenomic Analysis Suggests Chemical-Induced Sexual Dimorphism in the Expression of Metabolic Genes in Zebrafish Liver |
| PMC3525723__F4 | Insulin signaling transduction |
| PMC3526371__F1 | NFKB activation in pathogenesis and therapy of cancer |
| PMC3526508__F2 | Becoming a follicular or a MZ B-cell? |
| PMC3526895__F9 | Schematic model of the signaling pathway activated by redox/metabolic imbalance and its possible positive impact on human lifespan |
| PMC3527145__F1 | The left-right asymmetry pathway |
| PMC3527239__F2 | Metabolic pathways of TAG synthesis and degradation and their subcellular localization (adapted from and ) |
| PMC3527322__F1 | Amniotic fluid stem cells to study mTOR signaling in differentiation |
| PMC3527539__F7 | Up-regulated miR155 Reverses the Epithelial-mesenchymal Transition Induced by EGF and Increases Chemo-sensitivity to Cisplatin in Human Caski Cervical Cancer Cells |
| PMC3527608__F6 | Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms |
| PMC3527701__F2 | Mammalian N-end rule pathway.,,, N-terminal residues are indicated by single-letter abbreviations for amino acids |
| PMC3527886__F2 | Network of biglycan signaling in osteoblast differentiation and stabilizing role of biglycan in skeletal muscle |
| PMC3527976__F2 | Two rapamycin-sensitive myogenic mTOR signaling pathways |
| PMC3528279__F2 | Toll-Like Receptors (TLR) signaling pathway involved in hMPV-induced gene expression in primary immune cells |
| PMC3528279__F3 | RIG-I/MAVS signaling pathway regulating hMPV-induced NFKB and IRF activation in airway epithelial cells |
| PMC3528293__F1 | Generalized overview of the extrinsic and intrinsic apoptosis pathways |
| PMC3528378__F3 | Mechanism of muscle protein synthesis inhibition by GCs |
| PMC3528566__F2 | Carbohydrate metabolism and ATP synthesis |
| PMC3528620__F4 | Chemokine Signaling Pathway from the KEGG database (ID: mmu04062) overlaid with log2 fold change values for genes differentially expressed between DBA/2 and C57BL/6 at day 14 |
| PMC3528779__F6 | Global Effect of Inauhzin on Human p53-Responsive Transcriptome |
| PMC3529366__F6 | BMP2-WNT4-FOXO1 pathway in HESC differentiation |
| PMC3529395__F3 | LIPOPROTEIN RECEPTORS - AN EVOLUTIONARILY ANCIENT MULTIFUNCTIONAL RECEPTOR FAMILY |
| PMC3529568__F1 | TGFB latency, activation and signal transduction |
| PMC3529674__F5 | MyD88-independent TLR signaling |
| PMC3529762__F11 | Illustration of GnRH signaling pathways necessary for FSHB induction |
| PMC3529804__F3 | Novel Directions for Diabetes Mellitus Drug Discovery |
| PMC3529810__F7 | Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response |
| PMC3530456__F5 | Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis |
| PMC3530555__F5 | Combined Inhibition of IGF-1R/IR and Src Family Kinases Enhances Antitumor Effects in Prostate Cancer by Decreasing Activated Survival Pathways |
| PMC3530773__F3 | Vasopressin signaling network |
| PMC3531074__F3 | Network exploration options |
| PMC3531239__F5 | Proposed pathway of urinary carnitine loss by cisplatin in wildtype mice (A) but not in Oct1/2(-/-) mice (B) |
| PMC3531240__F11 | IFNA and LPS up-regulate APOBEC3 (A3) mRNA through different signaling pathways |
| PMC3531289__F1 | Chapter 3: Small Molecules and Disease |
| PMC3531707__F3 | PERK signaling under virus attack |
| PMC3531712__F1 | p62-interacting partners and functions |
| PMC3531730__F6 | Proposed model for the signaling pathway mediating NFKB activation induced by C-type lectin receptors |
| PMC3531794__F1 | Impact of IL-27 on lymphocyte signaling pathways |
| PMC3531868__F1 | Receptors for IL4 and IL13 are comprised of four different subunits, IL4RA (green), gamma chain (Gc; purple), IL13RA1 (red), and IL13RA2 (yellow) |
| PMC3532050__F1 | NFKB inhibition by A20 in the TNFR1 signaling pathway |
| PMC3532163__F4 | Characterization of the Phosphoproteome in SLE Patients |
| PMC3532179__F1 | Mathematical model of the apoptotic pathways induced by cisplatin |
| PMC3532271__F9 | Diagram of the AHK2- and AHK3-mediated cold-responsive transcriptional network in Arabidopsis |
| PMC3532379__F3 | Functional "DASE" networks |
| PMC3532456__F2 | Transforming growth factor (TGF)B signaling pathway |
| PMC3532456__F3 | Interleukin (IL)-13 and IL-4 signaling pathway |
| PMC3532605__F7 | NFKB signalling pathway |
| PMC3532876__F2 | Vicious spirals of repeating self-accelerating oxidative stress and dysregulated redox and information signaling as possible causes of type 2 diabetes |
| PMC3533285__F11 | SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation |
| PMC3533361__F1 | GSK3 signaling in neural development |
| PMC3533463__F1 | Biosynthesis pathways of phospholipid components in archaea |
| PMC3533466__F1 | Genes whose mRNA expression is suppressed by nicotine in RAW264.7 cells under poly(I:C) stimulation compared with those under poly(I:C) stimulation only are mapped to three gene networks, as predicted by ingenuity pathway analysis (IPA) |
| PMC3533466__F5 | Nicotine's effect on multiple signal transducers in the downstream pathway of calcium |
| PMC3533556__F7 | IL-13-induced airway mucus production is attenuated by MAPK13 inhibition |
| PMC3533650__F10 | Regulation of the FOXO3a survival, and glycolysis pathways under hypoxia in Spalax |
| PMC3534167__F2 | Hodgkin lymphoma |
| PMC3534236__F3 | Autophagy and selective deployment of Atg proteins in antiviral defense |
| PMC3534598__F1 | Cartoon depicting the role of sialidases during the multistep process of myogenesis |
| PMC3534691__F8 | Neuregulin Facilitates Nerve Regeneration by Speeding Schwann Cell Migration via ErbB2/3-Dependent FAK Pathway |
| PMC3534992__F7 | MiR-146b function in IEC-6 cells mediating TGFB signaling |
| PMC3534995__F2 | Canonical pathway representing LPS/IL-1-mediated inhibition of RXR function obtained by IPA from the analysis of HT29 data set |
| PMC3534995__F3 | Canonical pathway representing NRF2-mediated oxidative stress response obtained by IPA from the analysis of SW480 data set |
| PMC3535184__F4 | Ingenuity pathway analysis reveals the close relationship between 14 of 17 of most relevant genes in rectal cancer |
| PMC3535349__F1 | Iron homeostasis in absorptive enterocytes, macrophages, erythroblasts, and hepatocytes and its routes of circulation in the organism |
| PMC3535349__F2 | Iron transport across the placenta (syncytiotrophoblasts) |
| PMC3535427__F1 | Targeting 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) for colorectal cancer prevention and treatment |
| PMC3535741__F1 | PI3K/AKT/GSK3/mTOR signaling |
| PMC3536146__F8 | Pathway representation of canonical and Pyk2-mediated TLR9 signaling |
| PMC3536343__F1 | MTORC1 signaling to the translational machinery |
| PMC3536343__F2 | MTORC2 signaling pathway |
| PMC3536343__F4 | MAPK signaling to the translational machinery |
| PMC3536347__F1 | Pharmacologic inhibitors of the Wnt/Beta-catenin signaling pathway and known interactions with pathway components (see for references) |
| PMC3536347__F2 | Pharamcologic activators and enhancers of the Wnt/Beta-catenin signaling pathway and known interactions with pathway components (see for references) |
| PMC3536591__F2 | Ingenuity pathway analysis (IPA) top network that incorporates 9 genes identified as differentially methylated between methotrexate-naïve cases and controls by HM27 analysis |
| PMC3536698__F8 | IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling |
| PMC3537922__F1 | Unique host defense pathway: TRIF mediates both antiviral and antibacterial immune responses |
| PMC3538326__F7 | Proposed mechanisms of the reduced activation of G3139 in RIT-INPs |
| PMC3538421__F3 | Summary of P450 enzymes in cholesterol and bile acid biosynthesis |
| PMC3538421__F5 | Diagram showing the fundamental steps and P450 enzymes involved in vitamin D biosynthesis and degradation pathway |
| PMC3538588__F8 | Systems Biology Approach Reveals Genome to Phenome Correlation in Type 2 Diabetes |
| PMC3538603__F8 | Neural Stem Cell Death, Survival, and Differentiation in Response to Partial FGF-2 and EGF Deprivation. |
| PMC3539134__F2 | Inhibition of insulin signaling pathway by SOCS1 and SOCS3 |
| PMC3539252__F3 | Upregulated HCV gene signature is enriched for interferon (IFN) pathway genes |
| PMC3539299__F1 | The phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt pathway and its relationship to the androgen receptor (AR) based on the results of three papers published recently by the laboratories of Charles Sawyers, Damu Tang and Hong Wu |
| PMC3539509__F2 | TLR4 signaling pathway: TLR4 is localized on cell surface for ligand recognition and activates both MyD88-dependent pathway and TRIF-dependent pathway |
| PMC3539662__F1 | Kaposi sarcoma-associated herpesvirus K1 activates PI3K/AKT/mTOR signaling thereby activating protein synthesis and survival pathways, while inhibiting apoptotic pathways |
| PMC3539736__F3 | PI3K Signaling in B and T Lymphocytes: New Developments and Therapeutic Advances |
| PMC3539739__F1 | Oncogenic Transcription Factors: Cornerstones of Inflammation-Linked Pancreatic Carcinogenesis |
| PMC3539742__F2 | Autophagy and apoptosis- what's the connection? |
| PMC3539824__F2 | Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders |
| PMC3539910__F2 | Carcinogenesis of colorectal cancer cells and role of different miRNAs in cancer pathways |
| PMC3539919__F2 | Simplified carbon metabolic network |
| PMC3539953__F5 | Representation of the "Interferon Signaling" and "Toll-like Receptor Signaling" pathways |
| PMC3540089__F1 | PORPHOBILINOGEN DEAMINASE Deficiency Alters Vegetative and Reproductive Development and Causes Lesions in Arabidopsis |
| PMC3540170__F4 | Immunoregulatory role of anchored cAMP signaling in T cells |
| PMC3540819__F1 | Main signaling pathways involved in thyroid carcinogenesis are the MAPK and PI3K-AKT pathway (reproduced with permission) [] |
| PMC3540836__F1 | Experimentally supported and inferred factors of Drosophila triacylglycerol synthesis and mobilization at lipid storage droplets |
| PMC3540890__F1 | Biosynthetic pathway of prostaglandins |
| PMC3540985__F1 | CYTOKINES, INFLAMMATION AND COLON CANCER |
| PMC3541025__F1 | Autoinflammatory Disease Reloaded: A Clinical Perspective |
| PMC3541122__F6 | MiR-29 family is involved in multiple cellular processes |
| PMC3541196__F3 | Dysregulation of the cell cycle pathway during tumor progression |
| PMC3541267__F3 | Signaling pathways driving mesenchymal stem cells to differentiate into lineages found in reparative disorders |
| PMC3541279__F2 | Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury |
| PMC3541279__F5 | Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury |
| PMC3541283__F7 | FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway |
| PMC3541304__F1 | Protective autophagy induced by RBX1/ROC1 knockdown or CRL inactivation via modulating the DEPTOR-MTOR axis |
| PMC3541634__F1 | Schematic of TGFB1 signaling pathway and its regulation |
| PMC3541667__F5 | Hypothetic model explaining how KDM6 may contribute to definitive endoderm differentiation |
| PMC3542205__F5 | Illustration of the expression levels of enzymes within the glycolytic pathway and major connections in the C |
| PMC3542528__F4 | Protein network analysis of hits reveals multiple connections between signaling molecules and Golgi proteins |
| PMC3542528__F5 | Various subnetworks of signaling molecules that regulate Golgi structure |
| PMC3542934__F1 | TGFB signalling pathway |
| PMC3542954__F1 | Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosisEBV infection disrupts normal cell death and survival pathways in various human tumor cells, including lymphocytes, fibroblasts, and epithelial cells |
| PMC3543073__F2 | Three examples of chromatin-modifying complexes and their mode of action |
| PMC3543073__F4 | Bacterial nucleomodulins targeting chromatin |
| PMC3543090__F4 | MicroRNA-182-5p targets a network of genes involved in DNA repair. |
| PMC3543090__F8 | Model showing the effect of miR-182-5p on the DNA repair pathway |
| PMC3543749__F1 | Insulin/IGF-1 signaling pathway |
| PMC3543749__F2 | Telomere maintenance pathway |
| PMC3543845__F2 | Top network, "DNA Replication, Recombination, and Repair, Gene Expression, Cancer", formed by genes exhibiting altered expression in MLT-pretreated MCF-7 cells upon MMS exposure relative to untreated MMS-exposed cells |
| PMC3544113__F1 | Main deregulated signaling pathways in PMBCL |
| PMC3544185__F6 | Complex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-Stable Colorectal Cancer. |
| PMC3544293__F2 | MTOR signaling pathway |
| PMC3544722__F9 | Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase |
| PMC3544775__F3 | Laminin-211 in skeletal muscle function |
| PMC3544784__F1 | Insight into the role of CRMP2 (collapsin response mediator protein 2) in T lymphocyte migration |
| PMC3545289__F1 | Coordination between the endoreplication programme and cell growth during trichome development |
| PMC3545297__F1 | Energy metabolism in a typical mammalian cell |
| PMC3545532__F2 | Model depicting the canonical Nrf2 stress response pathway in each of the different phases: basal, preinduction, induction, postinduction |
| PMC3545710__F5 | Suggested pathway |
| PMC3545835__F1 | Principal platelet membrane receptors and signal transduction pathways |
| PMC3545927__F6 | High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome |
| PMC3546058__F1 | DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the omega-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways |
| PMC3546345__F5 | Vascular complications of diabetes: mechanisms of injury and protective factors |
| PMC3546685__F1 | Short-patch (SP-) and long-patch base excision repair (LP-BER) sub-pathways |
| PMC3546740__F2 | Simplified schematic overview of the biosynthesis of the main secondary metabolites stored and/or secreted by tomato glandular trichome cells |
| PMC3546894__F1 | Cytokine regulation of immune response cell phases through gender specific pathways |
| PMC3546894__F3 | Homeostatic role of IFNy pathway and IFNy-dependence of IL2 pathway in heathy men |
| PMC3546980__F7 | Irradiated Riboflavin Diminishes the Aggressiveness of Melanoma In Vitro and In Vivo |
| PMC3547105__F1 | The autotaxin-LPA-LPA1pathway |
| PMC3547110__F3 | Amplifying phase |
| PMC3547332__F5 | MicroRNA involvement in the inflammation, innate immunity, and oxidative stress pathways in AD and cancer |
| PMC3547545__F1 | An illustration of the IIF pathway genes.Notes: Arrows indicate the direction of signal transduction |
| PMC3547636__F2 | G Protein-coupled Receptor FPR1 as a Pharmacologic Target in Inflammation and Human Glioblastoma |
| PMC3547893__F1 | Interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility |
| PMC3547902__F2 | Autocrine functions of VEGF in breast tumor cells |
| PMC3547956__F6 | Transcriptional and Gene Regulatory Network of Lactococcus lactis MG1363 during Growth in Milk |
| PMC3548018__F2 | Integrated scheme for MIF expression, signal transduction and regulation of glucocorticoid immunosuppression and cell survival |
| PMC3548163__F2 | Modes of action of environmental risk factors for autism at excitatory synapses in the CNS |
| PMC3548172__F3 | Cooperation of esBAF and PRC2 during pluripotency maintenance |
| PMC3548426__F1 | Telomere syndromes |
| PMC3548977__F1 | Itraconazole and arsenic trioxide inhibit hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists |
| PMC3549263__F3 | Low-dose radiation responsive genes linked to carcinogenesis |
| PMC3549334__F7 | Ras activation by •NO-mediated processes in pancreatic cancer |
| PMC3549535__F3 | Innate immune stimulation by LPS positively impacts T cell priming |
| PMC3549669__F6 | STING Specifies IRF3 phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway |
| PMC3549672__F2 | Ubiquitination in Signaling to and Activation of IKK |
| PMC3549672__F3 | Ubiquitination in Signaling to and Activation of IKK |
| PMC3549674__F1 | New and emerging treatments for estrogen receptor-positive breast cancer: focus on everolimus. |
| PMC3551337__F2 | Major pathogenic lesions in MCL |
| PMC3551337__F3 | CRM1 regulates the PI3K signaling pathway in MCL |
| PMC3551464__F1 | Control of cell adhesion during neuronal migration |
| PMC3551738__F3 | Network analysis of known SLE-associated genes |
| PMC3552145__F10 | PGN-induced miR-132 and miR-212 in TLR signaling |
| PMC3552307__F1 | Double-stranded and single-stranded RNA signaling pathway |
| PMC3552454__F4 | Advances in graft-versus-host disease biology and therapy |
| PMC3552512__F3 | Oncogenic signals regulate each stage of translation |
| PMC3552779__F1 | Aerobic glycolysis, the citric acid cycle, and key glycolytic shunts |
| PMC3552883__F8 | Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells |
| PMC3552884__F8 | Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells |
| PMC3553295__F3 | Cocaine and Withdrawal on the Mouse Nucleus Accumbens Transcriptome |
| PMC3553500__F7 | NleB, a bacterial effector with glycosyltransferase activity targets GADPH function to inhibit NFKB activation |
| PMC3553670__F3 | Signal transduction pathways and activation of the innate immune response |
| PMC3553975__F6 | Subnetworks identified from (a) Wang et al |
| PMC3553975__F8 | Subnetworks identified from (a) Loi et al |
| PMC3554122__F1 | Summary of checkpoint factors |
| PMC3554339__F1 | Actions of Nec-1 and its derivatives in a mouse system |
| PMC3554558__F1 | Putative role of VHL-HIF-EPO pathway in RCC progression |
| PMC3554567__F4 | Integration of Nodal and BMP Signals in the Heart Requires FoxH1 to Create Left-Right Differences in Cell Migration Rates That Direct Cardiac Asymmetry. |
| PMC3554623__F2 | Battle between Rotavirus and Its Host for Control of the Interferon Signaling Pathway |
| PMC3554769__F1 | Mathematical Model for MicroRNA in Lung Cancer |
| PMC3555197__F1 | LXRs and prostate physiology: potential beneficial actions of LXRs over prostate cancer |
| PMC3555201__F3 | HMGB1 in the tumor microenvironment and hypothesis of HMGB1 functioning via NF-kB and epigenetic pathways |
| PMC3555235__F4 | Predicted pathways by the Ingenuity Pathway Analysis software (IPA) according to microarrays results in peripheral blood mononuclear cells (PBMCs) |
| PMC3555518__F1 | Mechanism of miRNA expression and/or function perturbation |
| PMC3556263__F1 | Molecular pathways affected by CR and irradiation |
| PMC3556327__F4 | Cholesterol biosynthesis theme analysis |
| PMC3556575__F5 | Pathways of relationships identified by feeding gene expression patterns identified in erythroid progenitors to the Ingenuity software |
| PMC3556981__F5 | Analysis of Central Metabolic Pathway Gene Expression with Compartmentalization Information.Heat maps in boxes indicate the expression of individual genes, and the chart plots indicate the aggregate expression levels of the pathway genes |
| PMC3557298__F4 | mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage |
| PMC3557433__F1 | Effector intercrossing network under physiological condition |
| PMC3557440__F4 | Schematic overview of the homologous recombination (HR) pathway |
| PMC3558412__F1 | Diagrammatic overview of the late stages of the HIV life-cycle |
| PMC3558493__F8 | ErbB2-Dependent Chemotaxis Requires Microtubule Capture and Stabilization Coordinated by Distinct Signaling Pathways |
| PMC355855__F10 | Models for repression of TGFB signaling by the Smurf-Smad7 complex and reactivation of TGFB signaling by the Jab1/CSN5-Smad7 complex |
| PMC3558831__F6 | PIAs recapitulate the activity of two tumor suppressors that converge on mTOR |
| PMC3558870__F1 | The potential disruption of hepatic GH signaling pathways by MC |
| PMC3559342__F3 | Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin |
| PMC3559342__F4 | Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin |
| PMC3559784__F5 | The Carcinogenic Liver Fluke, Clonorchis sinensis: New Assembly, Reannotation and Analysis of the Genome and Characterization of Tissue Transcriptomes |
| PMC3559810__F9 | Proposed leptin signaling pathway in adipose Sca-1+/CD45-/CD34+MSC cells |
| PMC3559989__F6 | Bayesian regulatory network and optimal regulatory pathway of p42.3 protein |
| PMC3560328__F2 | DNA interstrand crosslink repair and cancer |
| PMC3560328__F3 | DNA interstrand crosslink repair and cancer |
| PMC3560328__F4 | DNA interstrand crosslink repair and cancer |
| PMC3560376__F2 | The TLR9-Notch ligand (dll4) on Mycobacterium-dependent granuloma formation |
| PMC3560469__F2 | Angiotensins in the RAS |
| PMC3560666__F7 | Pathway in MAS and differentially expressed genes: as shown in Figure, IGSF4, PTPRC (CD45) and CD3D belong to a family of cell surface adhesion molecules |
| PMC3560853__F3 | Scheme showing the potential molecular events induced in cancer cells in the hypoxic tumour microenvironment |
| PMC3561014__F2 | Adjustments in root metabolism promote acclimation to deficiency |
| PMC3561376__F5 | Whole Genome Gene Expression Analysis Reveals CasiopeÃxadna-Induced Apoptosis Pathways |
| PMC3561376__F6 | Whole Genome Gene Expression Analysis Reveals CasiopeÃxadna-Induced Apoptosis Pathways |
| PMC3561517__F8 | Overview of the recruitment and modification of PCNA and Pol D by RNF8 involving different DNA damage pathways |
| PMC3561537__F6 | Scheme of EGFR signaling pathway activated by NEU3-induced GM3 reduction |
| PMC3561661__F1 | Activation and function of PI3K/Akt signaling in CD8 T cell |
| PMC3561798__F6 | Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis |
| PMC3561841__F1 | Why stress is BAD for cancer patients |
| PMC3562086__F1 | Connecting the Insulin pathway to the Drosophila autophagy machinery |
| PMC3562183__F2 | Expression Microarray Meta-Analysis Identifies Genes Associated with Ras/MAPK and Related Pathways in Progression of Muscle-Invasive Bladder Transition Cell Carcinoma |
| PMC3562241__F6 | Ihh and Runx2/Runx3 Signaling Interact to Coordinate Early Chondrogenesis: A Mouse Model |
| PMC3562293__F2 | Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities |
| PMC3562341__F4 | Accumulation of Splice Variants and Transcripts in Response to PI3K Inhibition in T Cells |
| PMC3562392__F3 | Cytoscape diagram of the functional interaction network representing proteins modulation in Pt1 interstitial fluid |
| PMC3562404__F2 | Biochemical relationships between the CDP-choline pathway of PtdCho synthesis, the degradation of PtdCho, and general phospholipid metabolism in mammals |
| PMC3562414__F2a | Surfactant phospholipid metabolism |
| PMC3562627__F2 | EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer |
| PMC3562679__F1 | Lipopolysaccharide (endotoxin) signaling pathway |
| PMC3562715__F2 | Oncogenic pathways in ABC-DLBCLThe stimulation of several surface receptors, including the B-cell receptor (BCR), CD40 or Toll-like receptors, triggers signaling cascades resulting in the activation of the NF-kB pathway |
| PMC3563076__F2 | Molecules involved during pancreatic development |
| PMC3563272__F4 | Eukaryotic Phospholipid Synthesis and Editing.G3P produced by GPDH is converted to PA by sequential acylation reactions regulated by GPAT and LPAAT |
| PMC3563405__F1 | represents the melanin synthesis in human, plants, fungi and bacteria starting from tyrosine whereas; (B & C) shows melanogenesis from secondary metabolites in fungi and bacteria respectively |
| PMC3563505__F6 | Functional partners of RB1 protein through STRING database |
| PMC3563611__F8 | Candidate miRNAs target genes involved in cell growth, survival, migration, and cell cycle progression |
| PMC3563666__F4 | Altered Cytokine Gene Expression in Peripheral Blood Monocytes across the Menstrual Cycle in Primary Dysmenorrhea: A Case-Control Study |
| PMC3564018__F10 | Stress-suppressed genes involved in antigen presentation and synapse formation |
| PMC3564018__F7 | Transcription factors predicted to be inhibited by battlefield-like stressors and their targets among stress-modulated genes |
| PMC3564224__F2 | Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47 |
| PMC3564490__F3 | Proposed alternative pathway of feto-placental androgen synthesis from 17-hydroxypregnenolone |
| PMC3564524__F10 | Novel signaling pathways involved in apo(a)-mediated effects on vascular endothelial cells |
| PMC3564914__F1 | Transcriptome analysis of bitter acid biosynthesis and precursor pathways in hop (Humulus lupulus) |
| PMC3565070__F3 | Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections |
| PMC3565104__F4 | Proposed model for progesterone and retinoid action in endometrium and endometriosis |
| PMC3565105__F1 | Hypothetical model illustrates the E2-ERA signaling pathway involving both genomic and extranuclear signaling pathways |
| PMC3565214__F1 | Major oncogenic signaling pathway alterations in urothelial carcinoma |
| PMC3565216__F1 | Phosphatidic Acid Plays a Central Role in the Transcriptional Regulation of Glycerophospholipid Synthesis in Saccharomyces cerevisiae |
| PMC3565254__F2 | Pathways involved in endocrine resistance |
| PMC3565264__F4a | Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct. |
| PMC3565315__F1 | Overview of the Hedgehog signaling pathway: a simplified model for Hh signaling in mammalian cells |
| PMC3565315__F2 | Overview about currently tested Hedgehog pathway inhibitors and their mode of action |
| PMC3565434__F8 | Schematic diagram of proposed CD44-regulated signaling pathway |
| PMC3565545__F10 | CHEK kinase pathway showing the role of CHEK proteins in cell cycle checkpoint control, and crosstalk with other pathways notably the P53 and BRCA pathways.Notes: Double circles indicate complex interactions involving multiple genes |
| PMC3565545__F9 | BRCA pathway showing the role of BRCA1 in DNA damage response and crosstalk with other biological pathways, notably the P53 pathway.Notes: Double circles indicate complex interactions involving multiple genes |
| PMC3565579__F1 | Proposed mechanism for opioid modulation for TLR |
| PMC3566011__F8 | HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion |
| PMC3566151__F1 | TGFB and TGFB/Smad Signaling in the Interactions between Echinococcus multilocularis and Its Hosts |
| PMC3567093__F6 | Somatostatin Derivative (smsDX) Targets Cellular Metabolism in Prostate Cancer Cells after Androgen Deprivation Therapy |
| PMC3567494__F1 | Two phosphoinositide cycles regulate aspects of lysosome function |
| PMC3567816__F1 | A summary of the newly proposed inflammasome activation pathway including PKRs' recently found role |
| PMC3567827__F1 | Hh signal transduction in Drosophila and mammalian systems |
| PMC3567829__F9 | miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops. |
| PMC3568227__F2 | Role of mesothelin in cancer progressionOverexpression of mesothelin leads to higher IL-6 production by constitutively activating NFKB |
| PMC3568263__F2 | Defective counterregulation and hypoglycemia unawareness in diabetes: Mechanisms and emerging treatments |
| PMC3568707__F1 | BiP as master regulator of the Unfolded Protein Response |
| PMC3569094__F1 | Novel therapeutic approaches for overcoming limitations in the gemcitabine pathway |
| PMC3569116__F1 | Glucose metabolic pathway |
| PMC3569619__F4 | NFkB activation pathway and its different inhibition steps |
| PMC3569837__F2 | Understanding metabolic regulation and its influence on cell physiology |
| PMC3570128__F2 | Wnt signaling affects c-Myb stability and activity |
| PMC3570203__F2 | Genes highly expressed in TNBC compared to HR-positive, HER2-negative breast cancer |
| PMC3570300__F5 | Ingenuity Pathway Analysis of proteins induced by DNP.A, overview of 15 specific functional networks, each of which contains 11 or more "focus" proteins (proteins that were significantly up- or down-regulated) |
| PMC3570385__F1 | Signal transduction pathway through TLR |
| PMC3570673__F6 | SIRT1 in the brain is involved in a number of processes that affect neuronal health, neurogenesis, and behavior |
| PMC3570980__F2 | The plant tetrapyrrole pathway with key enzymes and gun mutants |
| PMC3571113__F1 | Six important signaling networks of osteoblast differentiation |
| PMC3571329__F7 | Proposed metabolic model for syntrophic growth of D |
| PMC3571341__F12 | Proposed model of M-CSF-mediated organization of the osteoclast cytoskeleton |
| PMC3571350__F10 | Schematic model of IFN-induced apoptosis in WISH cells |
| PMC3571454__F10 | Models for intrinsic signaling by BST2 and for BST2 as a virus sensor |
| PMC3571654__F1 | shows the effects of osteoblast-secreted osteocalcin on glucose homeostasis and its novel role in regulating testosterone production in the leydig cells |
| PMC3571707__F1 | Adaptive Immune Responses and HER2/neu Positive Breast Cancer |
| PMC3571861__F4 | Metabolic engineering of E |
| PMC3572003__F1 | Altered energy metabolism in cancer |
| PMC3572009__F5 | Dysfunctional Activation of Neurotensin/IL-8 Pathway in Hepatocellular Carcinoma Is Associated with Increased Inflammatory Response in Microenvironment, More Epithelial Mesenchymal Transition in Cancer and Worse Prognosis in Patients |
| PMC3572057__F6 | Induction of CCL8/MCP-2 by Mycobacteria through the Activation of TLR2/PI3K/Akt Signaling Pathway |
| PMC3572136__F8 | Novel Pancreatic Endocrine Maturation Pathways Identified by Genomic Profiling and Causal Reasoning |
| PMC3572392__F4 | Almost all Theileria annulata proteins involved in glycolysis and citric acid cycle were identified in the study |
| PMC3572677__F1 | Scheme of apoptosis pathways |
| PMC3572738__F4 | Cellular iron balance |
| PMC3572906__F3 | Microbial Cell Components Induced Tolerance to Flagellin-Stimulated Inflammation through Toll-Like Receptor Pathways in Intestinal Epithelial Cells |
| PMC3573097__F7 | Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma |
| PMC3573143__F2 | Regulation of autophagy in response to stress |
| PMC3573271__F1 | Role of aryl hydrocarbnon receptor (AHR) signalling on CD4+ T cells |
| PMC3573348__F2 | Ingenuity Pathway Analysis (IPA) of genes differentially expressed in LRECb vs |
| PMC3573348__F3 | Ingenuity Pathway Analysis (IPA) of genes differentially expressed in LRECe vs |
| PMC3573348__F5 | Ingenuity Pathway Analysis (IPA) of genes differentially expressed in ECb vs |
| PMC3573419__F1 | Germinal-center B-cell-like (GCB) diffuse large B-cell lymphoma (DLBCL) derived from normal germinal-center centroblasts |
| PMC3573419__F2 | Activated B-cell-like (ABC) diffuse large B-cell lymphomas (DLBCLs) are derived from plasmablasts that are characterized by a block in differentiation |
| PMC3573709__F3 | Protein-protein interaction network of NFY and associated genes |
| PMC3573758__F2 | Development of allergic inflammation |
| PMC3573791__F1 | The metalloproteases meprin A and meprin B: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis. |
| PMC3573943__F1 | Regulation of cellular metabolism by p53 |
| PMC3574110__F4 | Differential Effects of Drug Interventions and Dietary Lifestyle in Developing Type 2 Diabetes and Complications: A Systems Biology Analysis in LDLr-/- Mice |
| PMC3574275__F1 | Structural and functional characteristics of the human CD38 molecule |
| PMC3574586__F2 | Schematic representation of the sessile and traditional serrated pathways |
| PMC3574811__F3 | Gallium-containing anticancer compounds |
| PMC3574814__F1 | MYC target genes in the polyamine pathway |
| PMC3574928__F1 | De novo purine biosynthetic pathway in humans |
| PMC3575444__F1 | PI3K-Akt pathway regulates polycomb group protein and stem cell maintenance |
| PMC3575449__F1 | From photomorphogenesis to cancer |
| PMC3575576__F6 | Proposed signaling pathway |
| PMC3575604__F1 | Evolution and impact of subclonal mutations in chronic lymphocytic leukemia |
| PMC3575666__F4 | VPS4B downregulation increases the expression of mitochondrial fatty acid Beta-oxidation related proteins and down regulates the expression of glycolysis related proteins in SKBR3 cells |
| PMC3575670__F5 | Precursor of myostatin is promyostatin and consists of a propeptide that binds to myostatin noncovalently to form an inactive complex |
| PMC3575708__F8 | Model for Ctip2 functions in the proliferation and differentiation of epidermal keratinocytes |
| PMC3575813__F10 | Presence of a diversity of Alu-mediated events in genes involved in apoptosis |
| PMC3575845__F7 | Anti-quiescence network mediated by the Myc-miR-22 pathway |
| PMC3575850__F8 | Hypothetical model for functional redundancy of Rad18 and NHEJ in responding to oxidative DNA damage during G1 |
| PMC3575868__F3 | Connective tissue growth factor (CTGF) stimulates the TGFBeta-Smad signalling pathway |
| PMC3576027__F2 | Activity-dependent neuronal signalling and autism spectrum disorder |
| PMC3576027__F3 | Activity-dependent neuronal signalling and autism spectrum disorder |
| PMC3576161__F1 | Folate metabolic pathway |
| PMC3576254__F5 | Pathway analysis |
| PMC3576710__F1 | Transmembrane protein UNC93B1 (black spring-like shape) associates with various toll-like receptors (horseshoe-like shapes) in the endoplasmic reticulum to help load them into vesicles coated with COPII for transport to the Golgi |
| PMC3576812__F1 | The hedgehog's tale: developing strategies for targeting cancer |
| PMC3576882__F4 | NFKB: Roles and Regulation In Different CD4+ T cell subsets |
| PMC3577635__F2 | Biochemical pathways leading to resistance to small-molecule epidermal growth factor receptor (EGFR)-targeting drugs such as gefitinib and erlotinib in non-small-cell lung cancer (NSCLC) |
| PMC3577660__F8 | Regulation of proteins translation in Jurkat cells |
| PMC3577828__F6 | Jejunal Proteins Secreted by db/db Mice or Insulin-Resistant Humans Impair the Insulin Signaling and Determine Insulin Resistance |
| PMC3577904__F3 | Gene Expression Analyses Implicate an Alternative Splicing Program in Regulating Contractile Gene Expression and Serum Response Factor Activity in Mice |
| PMC3577986__F1 | Gene Network Analysis of Small Molecules with Autoimmune Disease Associated Genes Predicts a Novel Strategy for Drug Efficacy |
| PMC3577986__F4 | Gene Network Analysis of Small Molecules with Autoimmune Disease Associated Genes Predicts a Novel Strategy for Drug Efficacy |
| PMC3577986__F6 | Gene Network Analysis of Small Molecules with Autoimmune Disease Associated Genes Predicts a Novel Strategy for Drug Efficacy |
| PMC3578033__F2 | Inflammation and Diabetes-Accelerated Atherosclerosis: Myeloid Cell Mediators |
| PMC3578301__F3 | Early signaling events that underlie fate decisions of naive CD4+ T cells towards distinct T-helper cell subsets |
| PMC3578301__F4 | Early signaling events that underlie fate decisions of naive CD4+ T cells towards distinct T-helper cell subsets |
| PMC3578363__F1 | G1 cell cycle control by the pRB pathway |
| PMC3578363__F4 | Targeting ubiquitin-dependent degradation of CDK inhibitors |
| PMC3578480__F2 | Molecular pathways associated with CPPs |
| PMC3578734__F1 | Scheme of CML hematopoietic stem cell signaling pathways in which predicted targets of microRNAs associated with CML are involved |
| PMC3578838__F14 | Reactive Oxygen Species via Redox Signaling to PI3K/AKT Pathway Contribute to the Malignant Growth of 4-Hydroxy Estradiol-Transformed Mammary Epithelial Cells |
| PMC3578923__F8 | Global Analysis of the Human Pathophenotypic Similarity Gene Network Merges Disease Module Components |
| PMC3578987__F2 | MITOCHONDRIAL GLUTATHIONE: FEATURES, REGULATION AND ROLE IN DISEASE |
| PMC3579143__F8 | The regulatory role of IRAK-M in TLR-IL-1R signalling |
| PMC3579281__F1 | Simplified overview of inflammation-orchestrated signal transduction that induces pro-tumourigenic responses in glioblastoma |
| PMC3579325__F3 | Selected pathways from enriched injured (EI) versus non-enriched (i.e., STD housed) injured (NI): demonstrating calcium signaling importance |
| PMC3579383__F1 | Myelin-derived neurite growth inhibitors, their receptors, and intracellular signaling pathway |
| PMC3579397__F1 | Sulfide production |
| PMC3579404__F1 | Conserved Wnt pathway branches and components |
| PMC3579516__F7 | Alliance for Cellular Signaling Plasmid Collection |
| PMC3579607__F1 | Mechanisms underlying HER2-directed therapy cardiotoxicity |
| PMC3579607__F2 | Mechanisms underlying modulation of HER2-directed therapy cardiotoxicity through aerobic exercise |
| PMC3579782__F6 | Early Activation of Rat Skeletal Muscle IL-6/STAT1/STAT3 Dependent Gene Expression in Resistance Exercise Linked to Hypertrophy |
| PMC3579806__F4 | Differentially Expressed miRNAs after GnRH Treatment and Their Potential Roles in FSH Regulation in Porcine Anterior Pituitary Cell |
| PMC3580164__F3 | Transcriptional integration of mitochondrial biogenesis |
| PMC3580185__F7 | Working model for the role of TAK1 lysine-72 in the negative regulation of TNFAlpha-induced NFKB activation |
| PMC3580410__F4 | Functional interaction sub-network constructed by using module 2 genes |
| PMC3580432__F2 | Possible key signaling components in the force-mediated stem cell differentiation |
| PMC3580541__F5 | TRAF6 and TRAF2/5 signaling pathways |
| PMC3580589__F3 | PTHrP signaling pathways during endochondral ossification |
| PMC3580761__F2 | Regulation network of CYP3A4 phenotype expression adapted from Klein et al |
| PMC3580884__F3 | Relationship between binding of ligands to the pattern recognition advance glycation end-product receptor (RAGE), and inflammation, gene expression, oxidative and nitrosative stress, and damage to the macro- and microvasculature |
| PMC3580961__F2 | Transcription at damaged DNA |
| PMC3581278__F2 | TNFA on regulation of inflammation, immue response, migration, and differentiation |
| PMC3581417__F1 | Synthesis of DNA precursors in the cytosol and mitochondria |
| PMC3581421__F8 | Coupling and S1P signaling in mesenchymal cells |
| PMC3581520__F1 | Differential Intrahepatic Phospholipid Zonation in Simple Steatosis and Nonalcoholic Steatohepatitis |
| PMC3581534__F5 | Bridging HIV-1 Cellular Latency and Clinical Long-Term Non-Progressor: An Interactomic View |
| PMC3581534__F7 | Bridging HIV-1 Cellular Latency and Clinical Long-Term Non-Progressor |
| PMC3581603__F6 | Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells |
| PMC3581799__F5 | Cell-to-cell signaling network generated by ingenuity pathway analysis of differentially expressed genes: Molecules are represented as nodes, and the biological relationship between two nodes is represented as an edge (line) |
| PMC3582104__F1 | The intracellular signaling pathways modulated by somatostatin receptors |
| PMC3582144__F7 | Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis |
| PMC3582273__F1 | CluePedia analysis example using expression data from human normal colon mucosa and colorectal tumors and in silico information |
| PMC3582304__F1 | Diagrammatic representation of the canonical Wnt signaling pathway |
| PMC3582304__F2 | Therapeutic targets of the Wnt signaling pathway |
| PMC3582569__F2 | Pathways regulated or induced by the presence of a specific sugar |
| PMC3582714__F1 | Sensing the immune microenvironment to coordinate T cell metabolism, differentiation & function |
| PMC3583082__F3 | This diagram summarizes the signaling pathway in thyroid carcinomas |
| PMC3583110__F2 | Intrinsic and extrinsic apoptotic pathways |
| PMC3583171__F3 | Significantly differentially expressed genes identified by KEGG as involved in toll-like receptor signaling |
| PMC3583293__F7 | Model depicting how Shh promotes CGNP proliferation through combined effects on Gli1/2 and the mTOR pathway components eIF4E and S6K |
| PMC3583555__F1 | Simple model for regulation of breast cancer initiating cells (BT-IC) self-renewal in breast cancer |
| PMC3583555__F2 | Regulation of apoptosis by several pathways |
| PMC3583581__F2 | Recent advances in prostate development and links to prostatic diseases |
| PMC3583581__F4 | Recent advances in prostate development and links to prostatic diseases. |
| PMC3584002__F7 | Model for GPN1, 2, and 3 function in biogenesis of RNA polymerases II and III |
| PMC3584306__F3 | Obesity Pharmacotherapy: Current Perspectives and Future Directions. |
| PMC3584589__F9 | Two mechanisms by which miR-200a regulates the activity of Beta-catenin |
| PMC3584666__F1 | Toll-like receptor (TLR) signaling pathway |
| PMC3584681__F2 | Pattern-recognition receptors (PRRs) and signaling pathways that lead to differentiation of antifungal T helper (Th) cells |
| PMC3584867__F9 | The multiple functions of PE |
| PMC3584916__F3 | Signaling pathway of IFIT family genes |
| PMC3584916__F4 | Antiviral and immune regulated function of IFIT family genes |
| PMC3585121__F6 | Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci |
| PMC3585130__F1 | The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network |
| PMC3585130__F2 | Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network |
| PMC3585156__F5 | Net Expression Inhibits the Growth of Pancreatic Ductal Adenocarcinoma Cell PL45 In Vitro and In Vivo |
| PMC3585432__F1 | The Drosophila Hippo pathway |
| PMC3585436__F2 | Simplified scheme showing the critical role of Class IA PI3Ks in multiple cellular functions |
| PMC3585436__F3 | p110D PI3K pathway in B cells |
| PMC3585436__F4 | p110D PI3K mediates the effects of CSF-1 or EGF via RhoA and PTEN in macrophages and some solid tumor cells |
| PMC3585940__F5 | Gene Expression Profile Analysis of Type 2 Diabetic Mouse Liver |
| PMC3586206__S1 | Schematic summarizing the effects of MIF on the canonical MAPK pathways |
| PMC3586350__F8 | Proposed Adipose Stromal Cell-derived IL-6 signaling pathway |
| PMC3586519__F1 | Schematic illustrating the cancer utilization of the metabolic pathways |
| PMC3586680__F1 | Schematic diagrams of WWOX structure and its role in signaling |
| PMC3586749__F4 | Epithelial to Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma |
| PMC3587611__F8 | Dullard/Ctdnep1 Modulates WNT Signalling Activity for the Formation of Primordial Germ Cells in the Mouse Embryo |
| PMC3587725__F1 | Regulation of AMP gene expression through the VDR or FXR pathways |
| PMC3587990__F1 | Scheme of PI3K/AKT mediated antiapoptotic regulations at the mitochondria |
| PMC3587990__F2 | Scheme of survival signaling cascade by receptor tyrosine kinases via PI3K/AKT mediated survival |
| PMC3587990__F3 | Pathway of apoptosis |
| PMC3587990__F4 | Interaction of marine compounds on survival and apoptotic signaling molecules |
| PMC3587991__F1 | P53 signaling pathway interacts with chromatin-remodeling factors in response to DNA damage |
| PMC3587991__F2 | Chromatin-remodeling factors affect the cell cycle |
| PMC3587995__F2 | p53/p21/pRb/E2F and p16/pRb/E2F signaling pathway |
| PMC3588000__F1 | Biosynthesis of Phosphatidylethanolamine (PE) |
| PMC3588029__F3 | Regulation of PGC-1A–this schematic represents the relationship between nutrition, circadian clock and other regulatory factors involved in post-translational modification of PGC-1A and its consequent impact on metabolic genes and aging |
| PMC3588051__F3 | Ingenuity Pathway analysis of lung cancer and/or COPD versus controls revealed NFKB as a major foundation |
| PMC3588076__F2 | mTOR signalling pathway |
| PMC3588076__F3 | Regulatory networks of mTOR inhibitors and miRNAs in controlling the mTOR pathway in cancer |
| PMC3588168__F1 | Simplified schematic of signaling pathways driving resistance to BRAF inhibitors |
| PMC3588179__F2 | T-cell immune regulation by IDO1 |
| PMC3588179__F4 | The mechanism of IDO1 regulation on viral infectious diseases |
| PMC3588201__F1 | Gene regulatory networks for cDC and pDC development |
| PMC3588864__F7 | Possible mechanisms of estrogen/androgen action in the prevention of NAFLD/NASH |
| PMC3589096__F2 | SREBP activation and input from mTORC1 signalling |
| PMC3589124__F7 | FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage |
| PMC3589238__F6 | Networks wherein various signaling pathways epigenetically affected by MXC exposure intersect and the relationships between affected molecules |
| PMC3589543__F7 | A pathway choice model for repair of a DNA DSB in Arabidopsis |
| PMC3589551__F2 | Regulation of LTP induction in the hippocampus by NRG1-ErbB4 signaling through suppressing Src enhancement of NMDARs |
| PMC3589553__F3 | Regulatory mechanisms for the Hippo pathway |
| PMC3589701__F3 | The epidermal growth factor receptor (EGFR) signaling pathway and molecules that may affect drug resistance |
| PMC3589702__F2 | Targeting of the hepatocyte growth factor (HGF)/MET pathway |
| PMC3589762__F2 | Pathways regulating intestinal sterol absorption and homeostasis |
| PMC3589914__F5 | Regulatory circuits operating in osteoblast lineage cells |
| PMC3590129__F7 | Differential Expression of miR-145 in Children with Kawasaki Disease |
| PMC3590201__F1 | Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations |
| PMC3590201__F2 | Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations |
| PMC3590201__F3 | Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations |
| PMC3590362__F1 | AGE/RAGE signaling pathway in NetSlim- This map represents the NetSlim reactions of AGE/RAGE signaling pathway in different cell types |
| PMC3590501__F6 | Proposed mechanism for the protective effects of carvacrol against hepatic steatosis in mice |
| PMC3590592__F6 | Proposed schematic representation of Wnt5a/Beta-catenin signaling in keloid pathogenesis |
| PMC3590661__F1 | Schematic overview of the impact of HDACi on DSB signalling, HR and NHEJ DNA repair pathways |
| PMC3590793__F1 | ATR barrier to replication-born DNA damage |
| PMC3591094__F8 | LPA-LPAR1/3 GAi2-mediated activation of p130Cas in cell migration |
| PMC3591264__F6 | Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression |
| PMC3591264__F7 | Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression |
| PMC3591455__F5 | Essential Role of the Zinc Transporter ZIP9/SLC39A9 in Regulating the Activations of Akt and Erk in B-Cell Receptor Signaling Pathway in DT40 Cells |
| PMC3591604__F2 | GPI anchor synthesis |
| PMC3591623__F7 | Model for the putative mechanism by which Fsk-cAMPi negatively regulates IL-2R signaling in human T-cells |
| PMC3592471__F8 | Functionally related pathways of aberrantly methylated and differentially expressed genes in immortalized MEFs |
| PMC3592971__F3 | Four simplified signaling pathways |
| PMC3593087__F1 | Pro-osteoblastogenic signal transduction by insulin and IGF1 receptors |
| PMC3593087__F3 | Cross-talk between insulin/IGF-1, BMP2, and Wnt signaling pathways |
| PMC3593299__F1 | Ghrelin neuroprotective pathways in Parkinson's disease |
| PMC3593794__F3 | PAFAH1B1 (platelet-activating factor acetylhydrolase 1 regulatory subnuit 1, formerly known as LIS1)-binding partners |
| PMC3593794__F6 | CDK5 phosphorylation substrates during neuronal migration |
| PMC3593900__F5 | Schematic illustrating how TNF acts via the Wnt pathway leading to the development of the myofibroblast phenotype |
| PMC3594038__F1 | Btk activates antiapoptotic pathways |
| PMC3594247__F1 | Hippo on the move |
| PMC3594312__F5 | Inactivation of DNA-Dependent Protein Kinase Promotes Heat-Induced Apoptosis Independently of Heat-Shock Protein Induction in Human Cancer Cell Lines |
| PMC3594407__F8 | Signaling pathway by which Beta-catenin may regulate intricate inflammatory responses in liver IRI |
| PMC3594520__F1 | TLR3 immunity to infection in mice and humans |
| PMC3594545__F2 | Regulation of NFKB by Ubiquitination |
| PMC3594740__F1 | TLR signaling |
| PMC3594751__F7 | Schematic view of the roles of S-PCNA and Srs2 in the rescue of stalled replication forks |
| PMC3594782__F1 | Serotonergic transcriptional networks and potential importance to mental health |
| PMC3594938__F5 | Cell type-specific outcomes of KSHV interactions with CD36 and CD147 signaling pathways |
| PMC3594951__F1 | This figure schematically shows the tyrosine kinase receptors, such as RET, EGFR, FGFR, MET, KIT, VEGFR, PDGFR, and some of their downstream effectors |
| PMC3594971__F3 | c-jun N-terminal kinase (JNK) pathway in postmitotic migrating neurons |
| PMC3595017__F1 | Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses |
| PMC3595301__F1 | Canonical or Wnt/Beta-catenin-TCF/LEF signaling |
| PMC3595309__F5 | Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFKB signaling pathway |
| PMC3595616__F1 | The branched isoprenoid pathway |
| PMC3596529__F1 | Intrinsic control of axon regeneration |
| PMC3596655__F8 | Proposed molecular mechanisms of the anti-inflammatory effects of allosteric SHIP1 activation |
| PMC3596735__F3 | ERK/MEK pathway |
| PMC3596735__F5 | Mechanism of response to anti-EGFR inhibitors |
| PMC3597092__F3 | Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR |
| PMC3597360__F4 | Pathways leading to actin polymerization in the myogenic response |
| PMC3597489__F4 | Conjunctival MicroRNA Expression in Inflammatory Trachomatous Scarring |
| PMC3597666__F5 | Representation of the top canonical pathway 'interferon signalling' detected when simultaneously analysing the mRNA and miRNA data sets with IPA |
| PMC3598075__F3 | Aminoacyl-tRNA synthetases in medicine and disease |
| PMC3598075__F4 | Aminoacyl-tRNA synthetases in medicine and disease |
| PMC3598331__F4 | Hindlimb transcriptional regulatory pathway genes suggested to be important in talipes equinovarus pathogenesis |
| PMC3598339__F2 | Pathway analysis identifies a network of genes related to lipid metabolism in islets cultured at 5.6 mM glucose concentration |
| PMC3598339__F3 | Network related to lipid metabolism in islets cultured at 23 mM glucose concentration |
| PMC3598339__F4 | Network related to cell cycle and cell death in islets cultured at 23 mM glucose concentration |
| PMC3598692__F8 | Toll-like receptor signaling pathway figure supplied by KEGG [[]] |
| PMC3598852__F3 | Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis |
| PMC3598852__F4 | Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis |
| PMC3598852__F5 | Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis |
| PMC3599046__F1 | JAK/STAT signaling pathway in response to MDV infection |
| PMC3599046__F2 | Toll-like receptor signaling pathway in response to MDV infection |
| PMC3599951__F5 | Phytochemicals targeting NFkB signaling pathway |
| PMC3600829__F4 | Functional analysis of the gene expression networks, performed using Ingenuity Pathway Analysis (IPA) |
| PMC3601079__F3 | Maslinic Acid-Enriched Diet Decreases Intestinal Tumorigenesis in ApcMin/+ Mice through Transcriptomic and Metabolomic Reprogramming |
| PMC3601164__F2 | Links between Toll-like receptor 4 and breast cancer |
| PMC3601164__F3 | Links between Toll-like receptor 4 and breast cancer |
| PMC3601265__F2 | Hypothetical pathways involved in MHC-self peptide-TCR recognition and PNH clone dominance |
| PMC3601410__F1 | Nrf2 is bound to Keap1 in the cytoplasm |
| PMC3601410__F2 | Most of the studies on Nrf2 and obesity-metabolic syndrome have focused on liver and white adipose tissue |
| PMC3601842__F1 | mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development |
| PMC3602223__F4 | Hepatocyte growth factor sensitizes brain tumors to c-MET kinase inhibition |
| PMC3602389__F2 | TGFB1 signaling pathway in vector arthropods |
| PMC3602516__F1 | Identification of Small Molecule Activators of BMP Signaling |
| PMC3602699__F9 | Summary of signaling pathway by which PP-fold peptides increase cell proliferation |
| PMC3602989__F2 | Leptin and cancer: Pathogenesis and modulation. |
| PMC3603002__F6 | T cell signaling pathways and protein phosphorylation sites identified to be differential between NOD and B6g7 mice in stimulated cells |
| PMC3603147__F7 | Inhibition of Na+-K+-2Cl- cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells |
| PMC3603280__F1 | SLC41 family of MgtE-like magnesium transporters |
| PMC3603396__F3 | Altered colonic metabolites during conventionalisation |
| PMC3603502__F10 | Redox regulation of signaling pathway leading to T-cell activation/proliferation |
| PMC3604032__F1 | PI3K/Akt/mTOR signaling in breast cancer |
| PMC3604104__F5 | Gene Expression Networks Underlying Ovarian Development in Wild Largemouth Bass (Micropterus salmoides) |
| PMC3604893__F1 | A) Model of multi-agent vs |
| PMC3605164__F2 | New insight into the mechanisms underlying the function of the incretin hormone glucagon-like peptide-1 in pancreatic Beta-cells |
| PMC3605242__F6 | Ingenuity Pathway Analysis visualization of oncogene interactions |
| PMC3605582__F1 | Key mediators of innate and adaptive immunity, development, and signalling |
| PMC3605881__F6 | Scheme of mechanisms underlying attenuation of cardiac dysfunction induced by endotoxin, after NG-R1 treatment |
| PMC3606047__F1 | Adenosine Signaling During Acute and Chronic Disease States |
| PMC3606085__F4 | NER pathway |
| PMC3606104__F3 | Identification of genetic networks that regulate the induction of filamentous growth |
| PMC3606422__F1 | Methotrexate mode of action |
| PMC3606533__F1 | Genes in choline/1-carbon metabolism and related pathways influence hepatic lipid balance |
| PMC3606625__F1 | EGFR-Targeted Therapy in Malignant Glioma: Novel Aspects and Mechanisms of Drug Resistance |
| PMC3606632__F6 | MTOR signaling pathway in KEGG pathway analysis |
| PMC3606754__F2 | STRING analysis of the relationship between genes |
| PMC3606754__F3 | NF-AT signaling and leukocyte interactions have been enriched by GeneGo |
| PMC3606787__F8 | Significant signaling pathway networks mined from nitroproteomic dataset |
| PMC3607076__F3 | ATM controls cellular survival in response to DNA damage through multiple pathways |
| PMC3607076__F4 | Selected summary of the ATM signaling network |
| PMC3607103__F3 | Recognition of nucleic acids by innate immune cells triggers cytokine production |
| PMC3607121__F1 | Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer |
| PMC3607163__F1 | Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential |
| PMC3607541__F6 | Interleukin-1 alpha modulates neutrophil recruitment in chronic inflammation induced by hydrocarbon oil |
| PMC3607621__F1 | Dark face of AMPK as an essential tumor promoter |
| PMC3607645__F5 | Epidermis model pathways |
| PMC3607745__F2 | Cytokine and downstream signalling pathways in liver ischaemia reperfusion injury |
| PMC3607786__F1 | MTOR signal pathway in autism spectrum disorders |
| PMC3608184__F1 | Cardioprotective mechanisms of T3 |
| PMC3608206__F4 | Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate |
| PMC3608394__F5 | Subnetworks identified from TCGA ovarian cancer gene expression data set |
| PMC3608394__F6 | Enriched pathways and GO functional annotations are: (a) ErbB signaling pathway: p=9.10e-13; Signal transduction p=2.33e-07 |
| PMC3608394__F7 | Enriched pathways and GO functional annotations are: (a) NFKB signaling pathway p=7.03e-05 |
| PMC3609013__F2 | Simplified overview of homologous recombination and non-homologous end-joining |
| PMC3609760__F5 | Transcriptional Profiling of Rice Early Response to Magnaporthe oryzae Identified OsWRKYs as Important Regulators in Rice Blast Resistance |
| PMC3609811__F1 | Gene Expression Profile of the Hippocampus of Rats Subjected to Chronic Immobilization Stress |
| PMC3609811__F2 | Gene Expression Profile of the Hippocampus of Rats Subjected to Chronic Immobilization Stress |
| PMC3610115__F1 | Metabolic pathway of tramadol |
| PMC3610211__F1 | TSC/mTORC1 signaling pathway at the neuronal synapse |
| PMC3610285__F2 | elanogenesi |
| PMC3610375__F1 | The Role of Vitamin D Deficiency in the Incidence, Progression, and Complications of Type 1 Diabetes Mellitus |
| PMC3610926__F2 | Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII |
| PMC3611005__F10 | LKB1-SIK2/3-class IIa HDAC pathway as a novel signaling module |
| PMC3612022__F6 | Proposed synergistic pathway to mitotic cell death in cells treated with a combination of paclitaxel and gefitinib or the PLK1 inhibitor BI2536 |
| PMC3612034__F3 | Identifying Resistance Mechanisms against Five Tyrosine Kinase Inhibitors Targeting the ERBB/RAS Pathway in 45 Cancer Cell Lines |
| PMC3612035__F7 | Non-Canonical CRL4A/4BCDT2 Interacts with RAD18 to Modulate Post Replication Repair and Cell Survival |
| PMC3612515__F1 | Graphical representation of Ingenuity Pathway Analysis results showing significant predictors genes in 'Gene Expression, Cell Cycle, Cancer' pathway |
| PMC3612515__F2 | Graphical representation of Ingenuity Pathway Analysis results showing significant predictor genes in 'InflammatoryResponse, Cell Death, Infection Mechanism' pathway |
| PMC3612515__F3 | Graphical representation of Ingenuity Pathway Analysis results showing considerable overlap of the significantpredictor genes in the significant biologic pathways |
| PMC3612647__F1 | A lithium-sensitive family of small-molecule phosphatases and the sulfate assimilation pathway |
| PMC3612776__F1 | Pathways affected in monogenic hypertensive disease |
| PMC3612853__F1 | Signaling and transcriptional regulation of Th17 polarization |
| PMC3612991__F2 | Harmonies Played by TGFB in Stem Cell Biology |
| PMC3613056__F7 | Pathway scheme of baicalein on the cell proliferation inhibition and cell metastasis inhibition in human bladder cancer cell 5637 |
| PMC3613369__F3 | Intra-Tumoral Heterogeneity in Metastatic Potential and Survival Signaling between Iso-Clonal HCT116 and HCT116b Human Colon Carcinoma Cell Lines |
| PMC3613593__F1 | Hedgehog pathway |
| PMC3613823__F8 | The proposed therapeutic mechanism of caspase-7 ablation in ADRP T17M RHO retinas |
| PMC3613825__F8 | Proposed model of regulation of pro-apoptotic signaling pathway by miR-128 |
| PMC3613856__F7 | Association of Luteinizing hormone receptor (LHR) mRNA with its binding protein leads to decapping and degradation of the mRNA in the p bodies |
| PMC3613937__F1 | Desmoglein-1, differentiation, and disease |
| PMC3614006__F1 | Regulation of Akt Activation by the PI 3-K pathway |
| PMC3614012__F2 | IGF-1R and EGFR/HER2crosstalk occurs by two main mechanisms |
| PMC3614013__F2 | Dietary adenine controls adult lifespan via adenosine nucleotide biosynthesis and AMPK, and regulates the longevity benefit of caloric restriction |
| PMC3614443__F1 | TOC1 and the interactions with the ABA signalling pathway |
| PMC3614492__F1 | Calciomics: integrative studies of Ca2+-binding proteins and their interactomes in biological systems |
| PMC3614511__F8 | Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGFB-TAK1-Dependent Mechanism |
| PMC3614663__F1 | Diagram showing the crosstalk between the DNA damage response pathway and BMP-controlled osterix expression and osteoblast differentiation |
| PMC3614848__F2 | STRING interaction for proteins studied to find relevant networks in RCC |
| PMC3615463__F1 | Phosphoinositide 3-Kinase Inhibition in Chronic Lymphocytic Leukemia |
| PMC3615616__F1 | Self-renewal and differentiation of gastric stem cells |
| PMC3615671__F2 | Metabolic modulation of epigenetics in gliomas |
| PMC3615733__F6 | Summary of anti-inflammatory roles of BSNXD in atherosclerosis |
| PMC3615879__F4 | Action of 20-HETE.Notes: Mitogens and ligands of G-protein-coupled receptors activate PLA2 and induce release of arachidonic acid, which is converted by CYP4A/F to 20-HETE |
| PMC3615883__F1 | G1 to S phase cell cycle transition regulators.Abbreviations: S, synthesis; G1, Gap 1 |
| PMC3615902__F3 | Developmental data alters disease mechanism prediction |
| PMC3616003__F10 | MicroRNA-301a Mediated Regulation of Kv4.2 in Diabetes: Identification of Key Modulators |
| PMC3616148__F2 | Roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability |
| PMC3616148__F3 | Roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability |
| PMC3616322__F2 | Signalling regulation of mammalian autophagy |
| PMC3616489__F3 | Emerging roles of E2Fs in cancer: an exit from cell cycle control |
| PMC3616609__F2 | The multi-step pathway of CENP-A-containing centromeric chromatin replication utilizing sequential, temporally separated steps across the mammalian cell cycle |
| PMC3616892__F6 | MTOR in CD4+ T cell differentiation |
| PMC3616967__F4 | Proposed model for iAs-induced birth defects via the GR pathway |
| PMC3616974__F6 | Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB |
| PMC3617041__F6 | TGFB restoration by SMAD6 knockdown |
| PMC3617098__F1 | Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1 |
| PMC3617288__F8 | Model for the new PLD2-Fes-Jak3 pathway |
| PMC3617338__F1 | Multivalency and conditional regulation at the cell surface |
| PMC3617635__F6 | CLL-induced Rho GTPase signaling defects in T cells that suppress LFA-1 activation signaling and migration and how this is reversible with lenalidomide |
| PMC3618178__F6 | Pharmacologic Inhibition of CXCL10 in Combination with Anti-malarial Therapy Eliminates Mortality Associated with Murine Model of Cerebral Malaria |
| PMC3618249__F2 | Single drug simulation result on T2D model |
| PMC3618249__F3 | combination drug simulation result on T2D model |
| PMC3618314__F7 | Characterization of CP genes in relation to the canonical TGFB signaling pathway |
| PMC3618441__F1 | Membrane-initiated Actions of Estradiol that Regulate Reproduction, Energy Balance and Body Temperature |
| PMC3618452__F3 | Metabolomic Analysis Reveals Metabolic Disturbance in the Cortex and Hippocampus of Subchronic MK-801 Treated Rats |
| PMC3618475__F7 | A scheme of cross-talk interactions in the mechanism of liver IRI between IRF3-dependent Type-I IFN signaling downstream of TLR4 activation and HO-1/Nrf2 system |
| PMC3618522__F1 | Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway In Cancer Prevention and Treatment |
| PMC3618522__F2 | Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway In Cancer Prevention and Treatment |
| PMC3618530__F8 | Interleukin-1β enhances cell migration through AP-1 and NF-κB pathway dependent FGF2 expression in human corneal endothelial cells. |
| PMC3618688__F4 | Resection of Non-Small Cell Lung Cancers Reverses Tumor-Induced Gene Expression Changes in the Peripheral Immune System |
| PMC3618895__F4 | Significantly changing expression sub-networks in LMB hypothalamus |
| PMC3619006__F1 | Proposed model for PDGF-D signaling pathway that controls the processes of EMT |
| PMC3619548__F1 | Schematic summary of the most common mutations found in melanoma patients |
| PMC3620096__F1 | Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles |
| PMC3620110__F2 | Expression of GATA3 in MDA-MB-231 Triple-negative Breast Cancer Cells Induces a Growth Inhibitory Response to TGFß |
| PMC3620110__F6 | Expression of GATA3 in MDA-MB-231 Triple-negative Breast Cancer Cells Induces a Growth Inhibitory Response to TGFß |
| PMC3620319__F3 | An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes |
| PMC3620567__F1 | Ischemia-reperfusion injury in the diabetic myocardium is multi-factorial and complex |
| PMC3620715__F1 | Interactions between the growth factor and β-adrenergic receptor pathways |
| PMC3621012__F2 | Regulation of miRNA biogenesis and turnover in the immune system |
| PMC3621013__F5 | Control of Alternative Splicing in Immune Responses: Many Regulators, Many Predictions, Much Still to Learn |
| PMC3621284__F2 | Proposed role of aPKCs in synaptic plasticity: At most CNS synapses, strong synaptic input leads to an activation of PI3K signaling and PDK1 activation thereby (1) thereby leading to mTORC1 activation |
| PMC3621409__F5 | Evolution of mirrregulation |
| PMC3621568__F1 | TGFB transduces signaling through Smad and non-Smad signaling pathways |
| PMC3621569__F3 | Inversin functions as a switch between the canonical Wnt and non-canonical Wnt/PCP pathways |
| PMC3621569__F6 | Planar cell polarity pathway (PCP pathway, non-canonical pathway) cascade |
| PMC3621649__F1 | Targeted therapy pathways.Notes: Protein kinase B (AKT) is a serine/threonine-specific protein kinase that affects glucose metabolism, apoptosis, cell proliferation, transcription and cell migration |
| PMC3621754__F3 | MUC1-C Oncoprotein as a Target in Breast Cancer; Activation of Signaling Pathways and Therapeutic Approaches |
| PMC3621754__F5 | MUC1-C Oncoprotein as a Target in Breast Cancer; Activation of Signaling Pathways and Therapeutic Approaches |
| PMC3621754__F6 | MUC1-C Oncoprotein as a Target in Breast Cancer; Activation of Signaling Pathways and Therapeutic Approaches |
| PMC3622313__F1 | Regulation of HDL homeostasis by miRNAs |
| PMC3622708__F8 | Wnt3a/Beta-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signaling program |
| PMC3622753__F1 | Intracellular S100B on cell proliferation, differentiation, survival and motility |
| PMC3623009__F1 | Simplified scheme of the complement activation network |
| PMC3623255__F2 | Mass isotopomer labeling measurements of intracellular metabolites (red bars, after 8.0 h in growth phase I; green bars, after 14.25 h in growth phase II) arranged by pathways: fractional abundance over mass in context of the metabolic network |
| PMC3623255__F3 | Metabolic pathways in the periplasm and the cytoplasm |
| PMC3623586__F2 | Schematic model of the regulation of intestinal homeostasis by the IL-22/STAT3 pathway in IECs |
| PMC3623797__F7 | Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells |
| PMC3623872__F5 | Nutrigenomics in Arma chinensis: Transcriptome Analysis of Arma chinensis Fed on Artificial Diet and Chinese Oak Silk Moth Antheraea pernyi Pupae |
| PMC3624298__F1 | Downregulation of human NK cell-mediated cytotoxicity pathway genes in response to Gal-9 |
| PMC3624394__F4 | Comparative analysis of NOTCH signaling pathway components in calcium-differentiated 8E6-iHFKs and GSI-treated C-HFKs by qRT-PCR |
| PMC3624606__F1 | Oncogenes and tumor suppressor modulate metabolic reprograming in cancer cells |
| PMC3624769__F1 | Interferon (IFN)-Gamma-activated pronecrotic and prosurvival signaling pathways |
| PMC3625357__F11 | IPA-generated gene network linking 88 of 445 genes shown by microarray analysis to be significantly (P < 0.01) up- (blue) or down- (red) regulated >twofold in bovine TCs in response to BMP6 treatment |
| PMC3625500__F5 | Overview on the mechanisms of glutathione induced cell death |
| PMC3625555__F3 | Neuroactive ligand-receptor interaction and calcium signaling pathway |
| PMC3625859__F3 | Regulation of angiogenesis by microRNAs (miRNAs) |
| PMC3625980__F7 | FBXW7A attenuates inflammatory signalling by downregulating C/EBPD and its target gene Tlr4 |
| PMC3626681__F1 | Molecular and biochemical studies in hyperlysinemia patients |
| PMC3626710__F5 | Results from single pathway sets |
| PMC3626841__F4 | Original model by Neumann et al |
| PMC3626870__F4 | Arsenic-mediated disruption of PI3K/AKT signaling pathway |
| PMC3627065__F6 | Integrated view of mammalian autophagy |
| PMC3627065__F8 | Factors situated at the interface between the ubiquitin-proteasome and the autophagy-lysosome degradative systems |
| PMC3627223__GA1 | The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway |
| PMC3627331__F1 | CD30 signals through TRAFs: upon stimulation by CD30L, CD30 recruits TRAF2 via interaction with its TRAF binding motif, resulting in TRAF2 degradation |
| PMC3627353__F2 | Genes and signaling pathways involved in ureteric budding |
| PMC3627353__F3 | Genes and signaling pathways involved in ureter development |
| PMC3627370__F1 | NAMPT in mammalian NAD metabolism |
| PMC3627549__F6 | Decreased Hepatotoxic Bile Acid Composition and Altered Synthesis in Progressive Human Nonalcoholic Fatty Liver Disease |
| PMC3627964__F2 | Proposed roles of Msi1-like (MSIL) proteins as regulators of the nutrient- and stress-sensing signaling pathways in fungi |
| PMC3627976__F1 | The polyamine pathway |
| PMC3628025__F7 | Proposed model suggesting that TGFB increases COX-2 levels and PGE2 secretion in prostate cancer cells and both TGFB and PGE2 activate PI3K/AKT/mTOR signaling pathway |
| PMC3628101__F1 | The novel NRP2A6B1-FAK-RAS-GLI1 axis involved in the regulation of tumour initiating cells in breast cancer |
| PMC3628288__F2 | Diagram of two potential molecular pathways of serrated neoplasia |
| PMC3628402__F6 | Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence |
| PMC3628696__F5 | Ingenuity Pathway Analysis (IPA) was performed with proteins where SUMO3 conjugation was 2- or more fold up-regulated in any gel slice |
| PMC3628745__F2 | New signaling network for melanoma |
| PMC3628764__F1 | Alternate routes of endocytic traffic of activated tyrosine kinase coupled cell surface receptors and the role of Cbl-family protein dependent ubiquitination |
| PMC3629228__F2 | De-Regulated MicroRNAs in Pediatric Cancer Stem Cells Target Pathways Involved in Cell Proliferation, Cell Cycle and Development |
| PMC3629761__F3 | B-cell receptor (BCR) signaling pathway and potential targets |
| PMC3630242__F1 | Leptin and adiponectin activate signaling components that integrate PI3K/Akt, RAS/MAPK, and pAMPK/mTor pathways |
| PMC3630363__F8 | Temporal restriction of the Cdk1/Cdc5/Mus81 pathway outside S phase is important for genome integrity |
| PMC3630382__F7 | Ingenity Pathway Analysis (IPA) from genes with loss of heterozygosity and somatic mutation (sample G05) |
| PMC3630382__F8 | "Cancer, Hematological Disease, Cell Cycle" Network |
| PMC3630382__F9 | Major interaction in top network |
| PMC3630382__F10 | "Cell Death and Survival, Cell Cycle, Cell-to-Cell Signaling and Interaction, Cellular Movement" Network |
| PMC3631012__F1 | Mi-2/NuRD complex making inroads into DNA-damage response pathway |
| PMC3631177__F2 | Expression of Glyceraldehyde-3-Phosphate Dehydrogenase Associated Cell Cycle (GACC) Genes Correlates with Cancer Stage and Poor Survival in Patients with Solid Tumors |
| PMC3631253__F4 | A Protein Prioritization Approach Tailored for the FA/BRCA Pathway. |
| PMC3631444__F6 | The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic genes in Leydig cells |
| PMC3631463__F8 | Combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation |
| PMC3631981__F1 | Interleukin 6 signaling scheme of the interleukin 6/signal transducer and activator of transcription 3 signaling pathway |
| PMC3632064__F3 | Motor axons release Agrin and ACh |
| PMC3632094__F8 | The process of LC3-associated phagocytosis (LAP) |
| PMC3632131__F1 | Shared network structure by non-small lung cancer pathway in KEGG and reconstructed co-expression networks using the CCA and GLASSO methods |
| PMC3632385__F2 | Schematic overview of estradiol-mediated genomic signaling pathway via ERA/B and rapid nongenomic signaling pathways via GPER, Gq-mER, and membrane subpopulation mERA/B |
| PMC3632399__F5 | RAS oncogene signaling |
| PMC3632418__F1 | mTOR as a potential treatment target for epilepsy |
| PMC3632562__F4 | PAK1 Protein Expression in the Auditory Cortex of Schizophrenia Subjects |
| PMC3632588__F6 | Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts-Secreted Interferon Beta |
| PMC3632591__F7 | RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats |
| PMC3632591__F8 | RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats |
| PMC3632609__F1 | Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain |
| PMC3632644__F2 | GLI1 Isoforms and cancer characteristics |
| PMC3632646__F2 | Regulation of GLI1 the isoforms by the canonical and noncanonical pathways |
| PMC3632658__F1 | Interplay between viruses and host mRNA degradation |
| PMC3632731__F1 | Network 1 (antigen presentation, cell-mediated immune response, and humoral immune response) generated by pathway analysis of the hot list |
| PMC3632731__F2 | Network 2 (metabolic disease, renal and urologic disease, and molecular transport) generated by pathway analysis of the hot list |
| PMC3633488__F3 | Decorin's effects on Beta-catenin and Myc stabilization by directly down-regulating EGFR and Met |
| PMC3633528__F1 | Cytokine signaling cascades that influence tropoelastin transcription |
| PMC3633815__F1 | MTOR signaling pathway |
| PMC3633842__F2 | Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns |
| PMC3633842__F4 | Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns |
| PMC3633842__F5 | Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns |
| PMC3633842__F6 | Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns |
| PMC3633862__F6 | Interferon-Beta Induces Distinct Gene Expression Response Patterns in Human Monocytes versus T cells |
| PMC3634068__F6 | Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters. |
| PMC3634196__F7 | Summary diagram of the proposed mechanisms underlying CA3 hypersensitivity, Alzheimer's disease protein induction, neuronal death and behavioural deficits following cerebral ischaemia in rats with LTED |
| PMC3634439__F3 | StarD7 in various cellular events in JEG-3 cells |
| PMC3634440__F1 | Gene regulatory networks of plant transcription factors (TFs) in plant abiotic stress responses and abscisic acid-dependent gene expression |
| PMC3634451__F2 | FGF signalling cascade in Drosophila melanogaster |
| PMC3634610__F2 | Signaling network of Dectin-1 |
| PMC3634610__F3 | ITAM-like-bearing CTLRs within the Dectin-1 cluster |
| PMC3634798__F1 | Stress response pathways |
| PMC3634825__F2 | Transcriptome Analysis of Skin Photoaging in Chinese Females Reveals the Involvement of Skin Homeostasis and Metabolic Changes |
| PMC3634825__F3 | Transcriptome Analysis of Skin Photoaging in Chinese Females Reveals the Involvement of Skin Homeostasis and Metabolic Changes |
| PMC3634910__F1 | Nutrient Signaling to mTOR and Cell Growth |
| PMC3634910__F2 | Nutrient Signaling to mTOR and Cell Growth |
| PMC3634910__F3 | Nutrient Signaling to mTOR and Cell Growth |
| PMC3635124__F1 | Shh signalling pathway1 |
| PMC3635523__F7 | Schematic model put forward the potential role of P4HB at different GBM cell states to TMZ treatment |
| PMC3635536__F5 | Signaling Pathways in Schizophrenia: emerging targets and therapeutic strategies |
| PMC3635737__F8 | CCDC22 deficiency in humans blunts activation of proinflammatory NFKB signaling |
| PMC3635745__F1 | Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways |
| PMC3635988__F12 | HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1 |
| PMC3636031__F9 | Early Apoptosis of Macrophages Modulated by Injection of Yersinia pestis YopK Promotes Progression of Primary Pneumonic Plague |
| PMC3636549__F2 | HEDGEHOG SIGNALING IN CHOLANGIOCYTES |
| PMC3636692__F3 | The VEGF-DLL4-Notch signaling pathway in angiogenic sprouts |
| PMC3636710__F9 | LBP/CD14-independent activation of host cells by E·albumin |
| PMC3636752__F1 | Distinct activation pathways for different CDKs |
| PMC3636756__F3 | CSF arrest is the result of a tight balance between PP2A-B55 and PP2A-B56 |
| PMC3636761__F1 | PI3K signaling pathway and the downstream targets of Akt |
| PMC3636885__F8 | STAT3-mediated coincidence detection regulates a noncanonical pathway of IEG induction |
| PMC3637405__F2 | Regulation of the p53-MDM2-MDMX pathway by DUBs |
| PMC3637678__F1 | MicroRNAs regulating myogenesis via PI3K/Akt signaling |
| PMC3637685__F2 | GAIT-mediated translational control |
| PMC3637854__F2 | Overview of UPR signaling |
| PMC3637951__F7 | FOXM1's role in thyroid cancer |
| PMC3637970__F1 | Transforming growth factorB (TGFB) signaling pathway |
| PMC3638038__F1 | Pluripotent Stem Cells: Immune to the Immune system? |
| PMC3638063__F1 | MTOR signaling pathway |
| PMC3638125__F2 | Intracellular signaling pathways of GLP-1R in the pancreatic Beta-cell |
| PMC3638243__F8 | The plasminogen (Plg)-dependent pathway of foam cell formation |
| PMC3638465__F1 | Metabolic map showing selected pathways of D |
| PMC3638621__F11 | The pathway map of urea cycle |
| PMC3638721__F7 | TRAIL-activated proapoptotic and antiapoptotic pathways |
| PMC3638770__F4 | Two major pathways to apoptosis |
| PMC3639292__F3 | Metabolic rewiring in melanoma engages more carbon than just glucose |
| PMC3639322__F3a | Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis |
| PMC3639415__F8 | The regulation and function of MYC in the androgen signaling pathway in molecular apocrine breast cancers |
| PMC3639655__F4 | Schematic depiction of c-Myc functional interactions with other pathways (for full discussion, see section Induction-Reversion Tumorigenesis in Animal Models by Oncogene-Driven Cancer Network Formation) |
| PMC3640280__F5 | A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance |
| PMC3640296__F2 | Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches |
| PMC3640296__F3 | Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches |
| PMC3640439__F1 | Induction and evasion of type I interferon responses by influenza viruses |
| PMC3640510__F2 | Diagram representing possible mechanisms linking HCV-induced oxidative stress with hepatocarcinogenesis |
| PMC3640511__F3 | PRR activated signaling and antiviral responses during virus infection |
| PMC3640917__F4 | Pathway for Death receptor signalling at 24 h post-M |
| PMC3640986__F2 | Steroid Receptor Coactivator-3 as a Potential Molecular Target for Cancer Therapy. |
| PMC3641099__F1 | Gene Expression Analysis of Peripheral Blood Cells Reveals Toll-Like Receptor Pathway Deregulation in Colorectal Cancer |
| PMC3641106__F8 | Differential Use of TLR2 and TLR9 in the Regulation of Immune Responses during the Infection with Trypanosoma cruzi |
| PMC3641131__F6 | Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways and Maintains Beta-Cell Phenotype in Human Islets |
| PMC3641182__F2 | Humanin: a harbinger of mitochondrial-derived peptides? |
| PMC3641604__F9 | The innate immune antiviral response triggered by IFNB and TNFA in AECs |
| PMC3641677__F4 | Mechanisms that Regulate Stem Cell Aging and Life Span |
| PMC3641842__F1 | The complement system |
| PMC3642145__F2 | FIP1L1/PDGFRA+ eosinophil signaling.FIP1L1/PDGFRA+ primary eosinophils express upregulated IL-5 receptor (IL-5RA) and JAK2/STAT5 pathway may be involved in FIP1L1/PDGFRA induced disease development(; ; ) |
| PMC3642156__F1 | Host immune response to viral infection (Interferon Signaling Pathways) |
| PMC3642326__F7 | CQ excites TRPA1 and TRPC3, sensitizes TRPV1, and inhibits TRPM8 through different signaling mechanisms |
| PMC3642384__F2 | Hypothetical evolutionary and functional relationship between Beta-catenin and nuclear transport receptors |
| PMC3642686__F4 | Schematic description of the MSR |
| PMC3642687__F1 | Pathway of reversible protein modification reactions that involve NAD+ consumption |
| PMC3643422__F1 | Illustration showing the overall sex hormone metabolic pathway and subpathways |
| PMC3643575__F4 | Arachidonic acid metabolism pathway where the differential genes and metabolites of colorectal cancer were annotated |
| PMC3644335__F2 | Cryptosporidium parvum scavenges LDL-derived cholesterol and micellar cholesterol internalized into enterocytes |
| PMC3644409__F7 | Proposed model showing molecular mechanisms of dysregulated immune pathways in diabetic renal tissues |
| PMC3644824__F2 | A schematic diagram of Mycobacterium tuberculosis (Mtb) infection and clearance via the autophagic pathway |
| PMC3645655__F3 | P53 and BRCA regulation of DNA repair represents a central component of altered cellular function in serous ovarian cancer |
| PMC3645661__F1 | An overview of signaling by the EGF family (with EGF and EGFR/ErbB1 as example) from cell surface down to the nucleus (without taking into account endocytic trafficking and recycling of the receptor) |
| PMC3645668__F1 | The canonical Notch signaling pathway |
| PMC3645678__F3 | Involvement of Cdc42, Rac1 and RhoA in vesicle trafficking, cellular transformation, invadopodia formation and metastasis |
| PMC3645738__F4 | Hypothetical time course of the unfolded protein response in mammals |
| PMC3645912__F1 | Induction and maintenance of IDO in dendritic cells |
| PMC3646067__F1 | Proposed scheme linking metabolic and signaling pathways to insulin resistance in the heart |
| PMC3646329__F2 | HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer |
| PMC3646399__F2 | Genetic-based biomarkers and next-generation sequencing: the future of personalized care in colorectal cancer |
| PMC3646677__F1 | B-Raf protein and signaling pathways |
| PMC3646763__F7 | Beyond the Binding Site: In Vivo Identification of tbx2, smarca5 and wnt5b as Molecular Targets of CNBP during Embryonic Development |
| PMC3646863__F4 | Prognostic signature of G‚‚ checkpoint function in melanoma cell lines |
| PMC3647962__F13 | TNFA signaling pathways to IKK activation |
| PMC3647990__F9 | Model for Rrp1 regulation of chitobiose metabolism in B |
| PMC3648073__F11 | Schematic diagram illustrating the signal transduction pathway involved in BDNF-mediated MMP-9 expression |
| PMC3648157__F7 | Dysregulation of cellular networks in the presence of PAN RNA expression |
| PMC3648215__F1 | Androgen regulation of epithelial-mesenchymal transition in prostate tumorigenesis |
| PMC3648340__F1 | Iron and Diabetes Risk |
| PMC3648498__F3 | Alzheimer's disease pathway from the KEGG database |
| PMC3648520__F1 | Roles of DNA Helicases in the Mediation and Regulation of Homologous Recombination. |
| PMC3648641__F1 | Unraveling Mechanisms Regulating Systemic Iron Homeostasis |
| PMC3648790__F4 | Interplay Between the Cancer Genome and Epigenome |
| PMC3649098__F3 | Signaling pathway for zinc prevention of atherosclerosis in monocytes/macrophages and vascular endothelial cells: a proposed hypothesis |
| PMC3649103__F1 | Hepatic glucose metabolism |
| PMC3649103__F2 | Hepatic ethanol metabolism |
| PMC3649201__F1 | Current view on the complex interplay of pathogenic factors in cholesterol gallstone formation |
| PMC3649343__F1 | The cholinergic anti-inflammatory pathway depicted |
| PMC3649977__F2 | STL-based Analysis of TRAIL-induced Apoptosis Challenges the Notion of Type I/Type II Cell Line Classification |
| PMC3650130__S85 | Recently, Zhang et al |
| PMC3650303__F5 | Post-translational modifications and interactions possibly involved in DSB repair pathway choice and HRR modulation |
| PMC3650458__F1 | Simplified overview of classical bile acid synthesis pathway in mice |
| PMC3650610__F1 | Therapeutic targeting of the p53 pathway in cancer stem cells |
| PMC3650616__F9 | MEK inhibition increases lapatinib sensitivity via modulation of FOXM1 |
| PMC3650620__F4 | Cross-talk between insulin and inflammatory signaling pathways |
| PMC3650722__F3 | Network was generated using Ingenuity Pathway Analysis (Ingenuity Systems, www.ingenuity.com) |
| PMC3651056__F2 | Arachidonic acid metabolic pathways and the role of IL-13 |
| PMC3651307__F1 | Toll-like Receptor (TLR) Signaling Pathways |
| PMC3651593__F1 | Pathway of Fbw7-mediated degradation |
| PMC3651771__F1 | Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1RAvB3 integrin complex in tumorigenesis and angiogenesis |
| PMC3652284__F1 | Regulation of Wnt/Beta-catenin Signaling within and from Osteocytes |
| PMC3652335__F2 | Lin28: Primal Regulator of Growth and Metabolism in Stem Cells |
| PMC3652374__F1 | Insulin signalling attenuates cAMP-mediated lipolysis at multiple steps in adipocytes |
| PMC3652374__F2 | Insulin signalling exerts rapid stimulation of glucose transport as well as fatty acid uptake, synthesis and esterification to triacylglycerol (TG) |
| PMC3652374__F4 | PPARG as a key regulator of lipogenesis in adipocytes and hypothetical major target for inhibitors of insulin-stimulated lipogenesis in obesity |
| PMC3652384__F2 | The mechanism of late PC |
| PMC3652575__F2 | Activation pathway of pDCs responding to viral nucleic acids and negative regulation of the pDC function by surface receptors |
| PMC3652637__F11 | Neural Regulation of Lacrimal Gland Secretory Processes: Relevance in Dry Eye Diseases |
| PMC3652647__F7 | Schematic model of probable pathway of refractoriness of interferonB signal |
| PMC3652659__F3 | Marginal zone B cells: virtues of innatelike antibody-producing lymphocytes |
| PMC3652739__F4 | Microarray analysis also indicated an increase in Wnt signaling and cell cycle regulation in women |
| PMC3652804__F1 | Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity |
| PMC3652812__F4 | Thymidylate Synthase Expression Determines Pemetrexed Targets and Resistance Development in Tumour Cells |
| PMC3652852__F7 | Peroxisome Proliferator-Activated Receptor (PPAR) G and PPARA Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders? |
| PMC3653035__F1 | Beta-Catenin plays two main functions in the cell |
| PMC3653035__F2 | Wnt ligands induce diverse Wnt pathways |
| PMC3653120__F3 | Effect of cigarette smoke on the etiology of colon carcinogenesis |
| PMC3653120__F4 | Effect of physical activity and obesity on the growth and development of colon carcinogenesis |
| PMC3653146__F1 | Possible signal pathway activated by cathelicidin (LL-37) to inhibit cell proliferation in gastric cancer cells |
| PMC3653416__F2 | Autophagy in alcohol-induced liver diseases |
| PMC3653431__F2 | Targeting the Hepcidin-Ferroportin Axis to Develop New Treatment Strategies for Anemia of Chronic Disease and Anemia of Inflammation |
| PMC3653888__F3 | Yin Yang 1 and Adipogenic Gene Network Expression in Longissimus Muscle of Beef Cattle in Response to Nutritional Management. |
| PMC3653888__F4 | Summary of YY1 gene network expression in steers comparing early weaning (EWS) against normal weaning without creep feeding (NWN) at 240 days on treatment.Notes: Cellular locations depicted are from the Ingenuity Pathway Analysis® knowledge base |
| PMC3653932__F7 | TLR4 Activates the Beta-catenin Pathway to Cause Intestinal Neoplasia |
| PMC3653945__F6 | Toll-Like Receptor -1, -2, and -6 Polymorphisms and Pulmonary Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis |
| PMC3654194__F1 | Spatial and temporal organization of ubiquitin networks |
| PMC3654365__F5 | Summary of the metabolic pathways in which the metabolites described in this paper are involved |
| PMC3654375__F1a | Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning |
| PMC3654375__F2a | Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning |
| PMC3654583__F1 | The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis |
| PMC3654985__F4 | Peritumoral (P) activated hepatic stellate cells (HSCs) and intratumoral myofibroblasts (T) |
| PMC3655322__F3 | Diagram showing some of the upstream elements of the proposed Hippo pathway |
| PMC3655322__F4 | Diagram showing some of the downstream elements of the proposed Hippo pathway |
| PMC3655383__F2 | Importance of white adipose tissue (WAT)-skeletal muscle crosstalk in cancer associated cachexia (CAC) and/or lipotoxicity |
| PMC3655867__F2 | Leptin deficiency disturbs the insulin signaling pathway JAK2/IRS/PI3K/AKT/AMPK and triggers diabetes |
| PMC3656004__F11 | Acetylcholine Promotes Ca2+and NO-Oscillations in Adipocytes Implicating Ca2+→NO→cGMP→cADP-ribose→Ca2+ Positive Feedback Loop - Modulatory Effects of Norepinephrine and Atrial Natriuretic Peptide |
| PMC3656404__F1 | Signaling pathways involving PKR-mediated inflammation and immune regulation |
| PMC3656432__F4 | Myostatin (Mstn) pathway |
| PMC3656449__F6 | The pathway triggered by Tat and leading to activation of ISGs by Tat in APCs infected by HIV |
| PMC3656649__F1 | ENDOCRINE RESISTANCE IN BREAST CANCER |
| PMC3656715__F1 | Hippocampal BDNF/TrkB signaling pathways that modulate depressive behavior and antidepressant responses |
| PMC3656827__F2 | Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury: a review |
| PMC3656947__F3 | PKC Activation Induces Inflammatory Response and Cell Death in Human Bronchial Epithelial Cells |
| PMC3657316__F3 | Ciliary signaling pathways implicated in control of cell proliferation |
| PMC3657461__F1 | Androgen receptor (AR) signaling in prostate cancer |
| PMC3657461__F3 | PI3K/AKT signaling in prostate cancer |
| PMC3657461__F4 | The JAK/STAT signaling in prostate cancer |
| PMC3657461__F5 | ERK and PI3K activation and their crosstalk |
| PMC3657461__F6 | TGFB/SMAD signaling pathway and its implication in prostate cancer |
| PMC3657461__F7 | Wnt signaling and its implications in the development of prostate cancer |
| PMC3657472__F1 | Genetic predisposition to peripheral nerve neoplasia: Diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromes |
| PMC3657575__F10 | The signaling pathways involved in calpain-mediated regulation of dendritic protein synthesis induced by BDNF |
| PMC3657702__F1 | Age-related alteration of gene expression in the TCR signaling pathway |
| PMC3658307__F2 | Liver Ischemia and Reperfusion Injury: New Insights Into Mechanisms of Innate - Adaptive Immune-Mediated Tissue Inflammation |
| PMC3658451__F2 | Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity |
| PMC3658475__F2 | P53/MDM2 regulation [] |
| PMC3659082__F7 | Insulin/IGF-1 Signaling, including Class II/III PI3Ks, Beta-Arrestin and SGK-1, Is Required in C. elegans to Maintain Pharyngeal Muscle Performance during Starvation |
| PMC3659299__F4 | Scheme depicting the current knowledge on PAC1-mediated signaling cascades resulting in a variety of neuronal outcomes |
| PMC3659509__F1 | Intracellular effects of soluble mediators are mainly mediated through the interaction with specific receptors that link extracellular signals up to modulation of gene expression |
| PMC3659569__F2 | Ginseng and Diabetes: The Evidences from In Vitro, Animal and Human Studies. |
| PMC3659771__F1 | Notch signaling in the vasculature |
| PMC3659771__F2 | Notch signaling in the vasculature |
| PMC3660063__F1 | Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response |
| PMC3660063__F2 | Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response |
| PMC3660063__F3 | Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response |
| PMC3660063__F4 | Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response |
| PMC3660156__F4 | Tumour dormancy and clinical implications in breast cancer |
| PMC3660182__F1 | Glia-mediated detrimental and beneficial inflammatory pathways in PD |
| PMC3660182__F4 | Crosstalk between inflammatory and Wnt/Beta-catenin signaling pathways in MPTP-induced SVZ plasticity |
| PMC3660250__F8 | Molecular Mechanisms of Environmental Enrichment: Impairments in Akt/GSK3B, Neurotrophin-3 and CREB Signaling |
| PMC3660516__F4 | Statins Are Associated with Reduced Risk of Esophageal Cancer, Particularly in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis |
| PMC3660694__F1 | Oncostatin M signaling pathway- NetSlim (http://www.netpath.org/netslim/NetSlim_114) map generated to graphically represent the different reactions induced by OSM in various cell types |
| PMC3660716__F1 | Intracellular signaling pathways recruited by leptin |
| PMC3660778__F8 | Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation |
| PMC3660828__F2 | Biosynthetic pathways of aminoglycerophospholipids |
| PMC3660828__F3 | Components involved in translocation of phospholipids to and within mitochondria of yeast |
| PMC3660846__F6 | From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited |
| PMC3661399__F7 | Selected AMPK and IGF-IR signalling pathways relevant to this study in normal (A) and hyperglycaemic (B) conditions |
| PMC3661706__F1 | Association between TLR4 and chitinase 3-like 1 (CHI3L1/YKL-40) signaling on colonic epithelial cells in inflammatory bowel disease and colitis-associated cancer |
| PMC3661940__F1 | Intrinsic somatodendritic and presynaptic modulation of action potential (AP) firing and transmitter release in 5-HT neurons |
| PMC3661948__F2 | Receptor-mediated regulation of KATP channels |
| PMC3662029__F1 | Mnk Kinases in Cytokine Signaling and Regulation of Cytokine Responses |
| PMC3662029__F4 | Mnk Kinases in Cytokine Signaling and Regulation of Cytokine Responses |
| PMC3662220__F1 | Novel zebrafish model reveals a critical role for mapk in lymphangiogenesis |
| PMC3662247__F3 | PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity |
| PMC3662247__F4 | PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity |
| PMC3662247__F6 | PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity |
| PMC3662904__F1 | Transforming growth factor (TGF)B signaling cascade |
| PMC3663255__F1 | Notch signaling pathway |
| PMC3663490__F5 | Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer. |
| PMC3663490__F6 | Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer. |
| PMC3663521__F7 | Schematic diagram illustrates the role of Dapper3 in UUO-induced renal fibrosis by regulating Wnt/Beta-catenin signaling |
| PMC3663533__F8 | The regulation of TLR signaling by Lgr4 |
| PMC3663800__F7 | New Algorithm for Integrated Analysis of miRNA-mRNA Interactions Based on Individual Classification Reveals Insights into Bladder Cancer |
| PMC3663800__F8 | New Algorithm for Integrated Analysis of miRNA-mRNA Interactions Based on Individual Classification Reveals Insights into Bladder Cancer |
| PMC3663815__F7 | Pathway summary of peptide array and antibody array results |
| PMC3663908__F1 | Major signaling pathways leading to cellular apoptosis |
| PMC3664143__F1 | A Novel High-Throughput 1536-well Notch1 Gamma-Secretase AlphaLISA Assay |
| PMC3665230__F6 | Pathway members of insulin/Akt signalling, TGFB, wnt signalling and inflammatory pathways that were regulated by prednisolone in 3T3-L1 cells |
| PMC3665263__F2 | Innate immune system in pneumococcal meningitis infection |
| PMC3665348__F8 | Summary of differential metabolism of procainamide in humans and mice |
| PMC3666170__F3 | Role of Cx43 and Panx1 hemichannels in paracrine signaling in taste transduction |
| PMC3666258__F5 | Diagram of norrin as a multifunctional ligand for three receptors/binding proteins |
| PMC3666312__F1 | Current landscape for T-cell targeting in autoimmunity and transplantation |
| PMC3666377__F3 | Functional Beta-cells respond to increasing glucose levels by increasing insulin secretion |
| PMC3666381__F1 | Metabolism in totipotent stem cells |
| PMC3666381__F2 | Metabolism in pluripotent stem cells |
| PMC3666388__F5 | Adult haemangioblast genetic regulatory network |
| PMC3666437__F5 | Regulation of upregulated miRNAs on the downregulated mRNAs in antigen processing and presentation pathway and p53 signaling pathway |
| PMC3666582__F7 | IDENTIFICATION AND DESCRIPTION OF A NOVEL MURINE MODEL FOR POLYTRAUMA AND SHOCK |
| PMC3666883__F11 | Sonic hedgehog-Dependent Induction of MicroRNA 31 and MicroRNA 150 Regulates Mycobacterium bovis BCG-Driven Toll-Like Receptor 2 Signaling |
| PMC3667241__F1 | Schematic drawings of the neuronal signaling pathways of anorexigenic and anxiogenic-like action in goldfish |
| PMC3667593__F5 | Abbreviated Pluripotent Cell Cycle |
| PMC3667651__F3 | Mechanisms underlying molecularly targeted therapeutics-induced cardiac toxicity |
| PMC3667713__F4 | Molecular Rheostat at the Interface of Cancer and Diabetes |
| PMC3667869__F1 | Resistance to EGFR targeted therapies |
| PMC3668058__F6 | Schematic representation of interacting fatty acid metabolic pathways in wild-type, D1, and D1o3-3 leaves |
| PMC3668182__F2 | Specification of GABAergic Cortical Interneurons |
| PMC3668263__F2 | LRRK2 regulates cell biological functions important for neurogenesis |
| PMC3668263__F3 | Wnt signaling pathways |
| PMC3668775__F9 | Proposed model for the attenuated response to type I IFNs in human pluripotent cells |
| PMC3668831__F1 | Iron regulation by hepcidin |
| PMC3668835__F4 | Genomic landscape of small intestine neuroendocrine tumors |
| PMC3669032__F6 | Canonical pathway analysis |
| PMC3669657__F6 | Observed effects of Hedgehog and Wnt inhibition, and Sox17 overexpression in HOG cells |
| PMC3669661__F1 | Phosphatidic Acid and Lipid Sensing by mTOR |
| PMC3669920__F1 | Schematic of neuregulin-ERBB4 signaling showing the roles of the products of the selected genes |
| PMC3670000__F2 | Signaling pathways used by GH to regulate growth and metabolism |
| PMC3670000__F3 | Signaling pathways activated by E2 and its crosstalk with GH |
| PMC3670113__F1 | Role of SHIP1 in bone biology |
| PMC3670175__F1 | Quantitative proteomics by amino acid labeling identifies novel NHR-49 regulated proteins in C. elegans |
| PMC3670237__F2 | STAT3 regulation of and by microRNAs in development and disease |
| PMC3670238__F1 | Spectrum of STAT functions in mammary gland development |
| PMC3670239__F1 | Infection-induced IL-10 and JAK-STAT |
| PMC3670240__F1 | Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells |
| PMC3670242__F1 | JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective |
| PMC3670266__F1 | Circulating miRNAs as new activators of the JAK-STAT3 pathway |
| PMC3670280__F3 | STAT1 as a central mediator of IFNG and TLR4 signal integration in vascular dysfunction |
| PMC3670289__F3 | Differential STAT3 signaling in the heart |
| PMC3670291__F2 | Roles of STATs signaling in cardiovascular diseases |
| PMC3670293__F1 | JAK-STAT pathway in hypertrophic stress signaling and genomic stress response |
| PMC3670293__F4 | JAK-STAT pathway in hypertrophic stress signaling and genomic stress response |
| PMC3670316__F7 | Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis. |
| PMC3670510__F1 | Targetable metabolic actors by natural compounds |
| PMC3670604__F4 | Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma |
| PMC3670665__F6 | Heat Shock Proteins Are Important Mediators of Skeletal Muscle Insulin Sensitivity |
| PMC3671248__F7 | Model for 20E regulation of IMD innate immune signalling |
| PMC3671250__F7 | Model depicting the refined Hippo pathway and step-wise LATS activation |
| PMC3671288__F2 | Inhibitory pathway of PGE2 in effector T cells |
| PMC3671299__F2 | Schematic diagram of AB accumulation mechanism |
| PMC3671630__F1 | Nucleotide excision repair |
| PMC3671665__F1 | Targeting the Sonic hedgehog signaling pathway by compounds and derivatives from natural products |
| PMC3671705__F1 | Targeted therapies for head and neck cancer |
| PMC3671705__F2 | mTOR signaling pathway |
| PMC3672007__F2 | Ingenuity pathways analysis canonical pathway IGF1 signaling This figure shows the IGF1 signaling pathway, with significantly upregulated genes in red, downregulated genes in green, and genes that did not meet our criteria for significance in gray |
| PMC3672537__F2 | Postulated interaction between the insulin signaling pathway and activation of the pro-inflammatory cascade in the pathogenesis of insulin resistance in sepsis |
| PMC3672663__F1 | The canonical Hedgehog signalling pathway in mammals |
| PMC3672663__F3 | Small-molecule Hedgehog pathway inhibitors and effects on the Hedgehog signalling pathway |
| PMC3672665__F1 | Epithelial cancer cell inflammatory response |
| PMC3672773__F1 | Schematic presentation of select miRNAs that regulate toll-like receptor signaling pathways |
| PMC3672788__F6 | Summary for the effect of calcineurin inhibitor, tacrolimus, on the regulation of RANKL expression through IL-6/sIL-6R/JAK2/STAT3/SOCS3 pathway |
| PMC3672943__F1 | Integration of Cell Signalling Pathways into Higher Order Networks Sculpts Transcriptional Landscapes |
| PMC3673040__F1 | Leptin is generated in adipose tissue and transported via the bloodstream to the hypothalamus |
| PMC3673784__F1 | Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition |
| PMC3673972__F10 | Antioxidant and Anti-Inflammatory Effects in RAW264.7 Macrophages of Malvidin, a Major Red Wine Polyphenol |
| PMC3674015__F1 | (A-C) Schematic overview of particle-based vaccines |
| PMC3674144__F1 | New look at TCR signaling to NFKB |
| PMC3674189__F7 | Estrogen receptor B ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis |
| PMC3674242__F7 | Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth |
| PMC3674381__F7 | Model of XIAP as a switch between type I and type II signaling |
| PMC3674397__F2 | Mechanisms of activity for sirtuins in Alzheimer's disease |
| PMC3674463__F1 | EGFR pathway and downstream signaling pathways, including KRAS |
| PMC3674567__F4 | Postulated model for regulation of large luteal cells of ruminants (left) and primates (right) |
| PMC3674623__F6 | Effect of sodium ferulate on caspase cascade apoptosis and IKK/NFKB pathways induced by TNF/TNF receptor |
| PMC3674720__F1 | The insulin-signaling pathway |
| PMC3675076__F5 | Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy |
| PMC3675167__F8 | Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol |
| PMC3675375__F1 | Wnt signaling pathway in diabetes mellitus |
| PMC3675380__F1 | Tumor necrosis factor receptor family molecules that possibly activate the PI3K-Akt pathway in T cells |
| PMC3675380__F2 | Synergy between TCR/CD28 and TNFR signalosomes for activation of the PI3K-Akt pathway in T cells |
| PMC3675586__F1 | Sugar nucleotide biosynthetic pathways identified in the genome of P |
| PMC3675657__F7 | Mechanisms for iron-dependent and iron-independent IRP2 regulation |
| PMC3675677__F1 | Insulin-like growth factor type I (IGF-1R) signaling axis |
| PMC3675828__F3 | Abundance distribution of cell cycle proteins |
| PMC3675894__F2 | Summary of association of genetic alterations of the HH pathway and cancer type |
| PMC3675900__F2 | Eicosanoids in Metabolic Syndrome |
| PMC3675946__F6 | Cell wall integrity (CWI) signaling pathway with transcriptomic expression changes during limonene stress |
| PMC3676112__F7 | Translation regulation of the mTOR signaling pathway and translation process |
| PMC3676171__F2 | Bile acid synthesis, conjugation, and biotransformation |
| PMC3676391__F1 | Saccharomyces cerevisiae Assay System to Investigate Ligand/AdipoR1 Interactions That Lead to Cellular Signaling |
| PMC3676649__F2 | Musashi signaling pathways associated with mammary progenitor cell expansion |
| PMC3676658__F1 | Schematic diagram showing the main components of the TGFB signaling pathway |
| PMC3676658__F3 | Schematic diagram summarizing available information obtained using animal models to investigate the role of TGFB signaling in wound healing |
| PMC3676754__F2a | The Brassinosteroid Signaling Pathway–New Key Players and Interconnections with Other Signaling Networks Crucial for Plant Development and Stress Tolerance |
| PMC3676786__F1 | Representative anti-angiogenic drugs and their targets in the angiogenic pathway |
| PMC3676795__F2 | Signaling cascades that regulate the intrinsic and extrinsic pathways of apoptosis |
| PMC3677135__F2 | Shh and Wnts guide commissural axons in the vertebrate spinal cord |
| PMC3677135__F6 | The canonical Shh signaling pathway |
| PMC3677135__F7 | Wnt signaling pathways |
| PMC3677135__F8 | Intracellular mechanisms underlying Wnt-induced axon guidance |
| PMC3677161__F5 | Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease |
| PMC3677579__F2 | Accessory molecules for Toll-like receptors and their function. |
| PMC3677627__F5 | Molecular network based on some key metabolites reversed by resina draconis or isosorbide dinitrate treatment |
| PMC3677821__F2 | Schematic showing some major pathways implicated in cancer progression using Drosophila studies |
| PMC3677900__F5 | Deguelin Action Involves c-Met and EGFR Signaling Pathways in Triple Negative Breast Cancer Cells |
| PMC3678031__F2 | The amygdala and medial prefrontal cortex: partners in the fear circuit |
| PMC3678388__F1 | Canonical ATR signaling pathway and functions of newly identified regulators.(A) ATR signaling is activated in response to single-stranded DNA gaps in the genome |
| PMC3678388__F3 | ATR recruitment to some DNA base lesions proceeds through a mismatch repair-dependent mechanism.Mismatch repair proteins may contribute directly and indirectly to ATR recognition of some times of DNA damage |
| PMC3678415__F1 | HDL metabolic pathways and current drugs under development |
| PMC3678415__F2 | HDL biogenesis |
| PMC3678537__F2 | Wound Healing in Development |
| PMC3678724__F1 | Alterations of the AKT pathway in human cancer |
| PMC3678733__F1 | Human Hippo signaling pathway |
| PMC3678733__F3 | Visualization of curated components of pathways and inferred interacting proteins and small molecules |
| PMC3678929__F2 | Insulin-like growth factor 1 receptor (IGF-1R) signaling pathway |
| PMC3679038__F7 | Involvement of ERK-Nrf-2 Signaling in Ionizing Radiation Induced Cell Death in Normal and Tumor Cells |
| PMC3679124__F6 | Plants Know Where It Hurts: Root and Shoot Jasmonic Acid Induction Elicit Differential Responses in Brassica oleracea |
| PMC3679268__F7 | GSK-3A Promotes Oncogenic KRAS Function in Pancreatic Cancer via TAK1-TAB Stabilization and Regulation of Non-Canonical NFKB |
| PMC3679380__F5 | Extranuclear and nontranscriptional effects of RA and vitamin A |
| PMC3679382__F8 | Working model of the FGF21 regulatory pathway under leucine deprivation |
| PMC3679383__S1 | Pathways of GPL biosynthesis in eukaryotic cells: temporal regulation of GPL-synthesizing enzyme activities |
| PMC3679459__F1 | TRAIL apoptotic pathway |
| PMC3679471__AF6 | MSP-RON signaling pathway |
| PMC3679475__F1 | Inflammatory adipokines suppress insulin signaling resulting in insulin resistance |
| PMC3679547__F1 | Canonical pathway analysis |
| PMC3680226__F6 | Analysis and Prediction of Pathways in HeLa Cells by Integrating Biological Levels of Organization with Systems-Biology Approaches |
| PMC3680388__F5 | Novel Strategy to Increase the Proliferative Potential of Adult Human Beta-Cells While Maintaining Their Differentiated Phenotype |
| PMC3680431__F7 | Acute-Phase Serum Amyloid A in Osteoarthritis: Regulatory Mechanism and Proinflammatory Properties |
| PMC3680752__F10 | A: the top-associated network as defined by Ingenuity Pathway Analysis (IPA) for NAc mRNAs upregulated in HVRs vs |
| PMC3680918__F6 | Schematic diagram of the PIP signaling pathway in ER-negative breast cancer |
| PMC3680934__F1 | Activation of TAZ upon epithelial-to-mesenchymal transition in human breast cancer cells |
| PMC3681194__F1 | Genes with mutations that cause monogenic, severe T-cell immunodeficiency in humans can be intrinsic to the thymic epithelium or to T cells |
| PMC3681204__F3 | Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines |
| PMC3681501__F5 | Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway |
| PMC368161__F7 | Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor |
| PMC3681689__F6 | Working model for the roles of the mitochondrial chaperones Ssq1-Jac1 and the glutaredoxin Grx5 in Fe/S protein maturation in eukaryotes |
| PMC3681701__F9 | Sources of sphingolipids for the parasite |
| PMC3681733__F2 | Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes. |
| PMC3681753__F8 | Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses |
| PMC3681875__F7 | Novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair |
| PMC3682205__F3 | Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair |
| PMC3682211__F7 | Aspirin targets multiple components of the AMPK/mTOR signaling pathway in colorectal cancer |
| PMC3682694__F1 | Roles of molecules explained in this review in signal transduction |
| PMC3682751__F3 | Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity |
| PMC3683050__F11 | Distinctive Profile of IsomiR Expression and Novel MicroRNAs in Rat Heart Left Ventricle |
| PMC3683326__F3 | GenMAPP schematic of cell cycle pathway genes |
| PMC3683338__F1 | Immune network in EOC |
| PMC3683810__F8 | Proposed model of p38 MAPK regulation of mRNA translation |
| PMC3683875__F1 | Nucleotide excision repair (NER) pathway |
| PMC3683896__F2 | Extrinsic and intrinsic pathways of apoptosis |
| PMC3683958__F3 | The dynamic regulation of NAD metabolism in mitochondria |
| PMC3684061__F4 | Genetic Risk Factors for Pancreatic Disorders |
| PMC3684083__F1 | EGFR/TGFA and TGFB/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets |
| PMC3684083__F2 | EGFR/TGFA and TGFB/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets |
| PMC3684083__F4 | EGFR/TGFA and TGFB/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets |
| PMC3684135__F1 | Transforming growth factor B (TGFB) signaling pathway in hypothermia |
| PMC3684282__F10 | Schematic of myelin-mediated activation of the TGFB signaling pathway and downregulation of Smad2 by SLPI |
| PMC3684427__F5 | The regulation of clot formation (colored entities) |
| PMC3684428__F1 | The adaptive unfolded protein response (UPR) |
| PMC3684428__F2 | IRE1Alpha- and PERK-mediated cell death pathways |
| PMC3684430__F1 | Apoptotic pathways regulated by the UPR |
| PMC3684860__F7 | Evolution of the Eye Transcriptome under Constant Darkness in Sinocyclocheilus Cavefish |
| PMC3685413__F2 | SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia |
| PMC3685463__F4 | Tetrapyrrole biosynthetic pathway and various transcription regulators in R |
| PMC3685590__F9 | Two CDC42 paralogs modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions |
| PMC3686324__F1 | Osteoporosis - a current view of pharmacological prevention and treatment. |
| PMC3686324__F3 | Osteoporosis - a current view of pharmacological prevention and treatment. |
| PMC3686512__F1 | Model depicting the role of Wls/Gpr177 in regulating the Wnt signaling pathway |
| PMC3686618__F6 | Main signaling pathways supposed to be activated in MEC exposed to either E |
| PMC3686733__F2 | Proteomic View of Interactions of Shiga Toxin-Producing Escherichia coli with the Intestinal Environment in Gnotobiotic Piglets |
| PMC3686787__F2 | Coregulation of Terpenoid Pathway Genes and Prediction of Isoprene Production in Bacillus subtilis Using Transcriptomics |
| PMC3686815__F9 | Regulated Extracellular Choline Acetyltransferase Activity– The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway |
| PMC3686839__F2 | Molecular Pathways: Extracting Medical Knowledge from High Throughput Genomic Data |
| PMC3687506__F1 | Mitochondrial dysfunction and defective mitochondrial biogenesis lead to insulin resistance and other risk factors of metabolic syndrome |
| PMC3687624__F1 | Simplified view of the canonical Wnt signaling pathway (Modified from ref |
| PMC3687783__F5 | Marked alterations in the distal gut microbiome linked to diet-induced obesity |
| PMC3687803__F1 | Different layers of the epidermis, and the functions within those layers regulated by VDR and its coactivators |
| PMC3687803__F3 | Canonical wnt signaling pathway |
| PMC3687869__F2 | Phosphatidylinositol-3-kinase/Akt signaling pathway |
| PMC3688269__F2 | Dysfunctional telomeres activate upstream checkpoint PI3 kinases, such as ATM (ataxia-telangiectasia mutated) or ATR (ataxia-telangiectasia and Rad3 related), - () |
| PMC3688534__F10 | Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of Ranbp2 in Cone Photoreceptors |
| PMC3688662__F1a | MODELS OF INSULIN RESISTANCE AND HEART FAILURE |
| PMC3688817__F8 | PPARB Regulates Liver Regeneration by Modulating Akt and E2f Signaling |
| PMC3688827__F6 | Transcriptome Analysis Reveals Novel Entry Mechanisms and a Central Role of SRC in Host Defense during High Multiplicity Mycobacterial Infection |
| PMC3688869__F5 | Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer |
| PMC3688919__F8 | microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model |
| PMC3689245__F7 | Proposed mechanism for MTX-induced melanosome transport in melanoma |
| PMC3689254__F2 | General scheme of EGFR activation |
| PMC3689254__F3 | EGFR activation of the Ras/Raf/MEK/MAPK pathway |
| PMC3689254__F6 | Several flavonoid compounds also target the Fyn/Src signaling pathway |
| PMC3689263__F2 | Signaling mechanisms important for endocrine resistance and which are currently targeted in clinical trials, combined with aromatase inhibitors |
| PMC3689575__F1 | Modeling the genetic basis for human sleep disorders in Drosophila |
| PMC3689711__F1 | Experimental Genetics of Plasmodium berghei NFU in the Apicoplast Iron-Sulfur Cluster Biogenesis Pathway |
| PMC3689841__F1 | Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation |
| PMC3689941__F9 | STAT3 pathway switching is induced by EMT during breast cancer progression |
| PMC3689995__F7 | Dual functions of Smad2 in the maintenance of hESC and mEpiSC pluripotency |
| PMC3690105__F1 | Metabolic pathway of clopidogrel |
| PMC3690116__F1 | Schematic model of FGF-2 and FGF-18 signaling pathways in articular cartilage and IVD |
| PMC3690345__F2 | Metabolic crossroads of iron and copper |
| PMC3690356__F1 | Calcium channels in T cells |
| PMC3690365__F2 | Pathways that control levels of macroautophagy |
| PMC3690396__F7 | Regulation of the Hippo pathway by cAMP-PKA signaling |
| PMC3690520__F3 | TCR signaling pathway leading to NFKB and JNK activation |
| PMC3690688__F8 | Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium |
| PMC3690774__F5 | Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17Beta-estradiol in embryonic zebrafish |
| PMC3690850__F7 | Working model for rotavirus cell entry |
| PMC3691184__F5 | Integrated miRNA-mRNA Analysis Revealing the Potential Roles of miRNAs in Chordomas |
| PMC3691204__F1 | Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma |
| PMC3691323__F6 | Role of Helicase-Like Transcription Factor (Hltf) in the G2/M Transition and Apoptosis in Brain |
| PMC3691611__F7 | The proposed pathways that regulate astroglial CNTF |
| PMC3691765__F1 | Apoptotic signaling pathways |
| PMC3691765__F4 | HTLV-1 and apoptotic signaling pathways |
| PMC3691869__F6 | Schematic outline of the regulation of EGFR internalization and mediated signaling by the CIN85-SH3GL2-Cbl complex |
| PMC3691915__F8 | Regulators of mitochondrial biogenesis and function |
| PMC3692130__F1 | Graphical representation of Wnt pathway as described in the KEGG repository () |
| PMC3692518__F4 | miRNA Signature of Mouse Helper T Cell Hyper-Proliferation |
| PMC3693006__F4 | Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells |
| PMC3693108__F1 | Therapeutic molecular targets for endometrial cancer |
| PMC3693188__F1 | TP53-centered network in CLL: A novel pathogenetic model for chronic lymphocytic leukemia (CLL) showing a pathway of microRNAs and cytogenics that are involved in the development of CLL |
| PMC3693462__F1 | BRCA1: A Missing Link in the Fanconi Anemia/BRCA Pathway |
| PMC3693464__F1 | Transcriptional Control of Cellular Metabolism by mTOR Signaling |
| PMC3693466__F1 | Insulin Signaling: Inositol Phosphates Get Into the Akt |
| PMC3693544__F1 | Transcriptional feedback in the insulin signalling pathway modulates ageing |
| PMC3693544__F2 | Transcriptional feedback in the insulin signalling pathway modulates ageing |
| PMC3693579__F5 | Signal transduction in MMTV-Pax8PPARG mice |
| PMC3693914__F2 | DA biosynthesis and degradation |
| PMC3694398__F5 | NFAT Gene Family in Inflammation and Cancer |
| PMC3694431__F5 | Interaction networks of significantly regulated genes from interconnected neurons 7 days post-infarct |
| PMC3694595__F1 | IL-33: A Novel Danger Signal System in Atopic Dermatitis |
| PMC3694614__F9 | Free Radical-Producing Myeloid-Derived Regulatory Cells: Potent Activators and Suppressors of Lung Inflammation and Airway Hyperresponsiveness. |
| PMC3694812__F1 | Towards Systematic Discovery of Signaling Networks in Budding Yeast Filamentous Growth Stress Response Using Interventional Phosphorylation Data |
| PMC3694812__F4 | Towards Systematic Discovery of Signaling Networks in Budding Yeast Filamentous Growth Stress Response Using Interventional Phosphorylation Data |
| PMC3694890__F8 | Novel Phosphopeptide Microarray Based Interactome Map in Breast Cancer Cells Reveals Phosphoprotein-GRB2 Cell Signaling Networks |
| PMC3694976__F10 | Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia |
| PMC3694992__F1 | Neuroimmune Signaling: A Key Component of Alcohol Abuse |
| PMC3695482__F2 | Focus on Histone variant H2AX: to be or not to be |
| PMC3695632__F3 | Case 19-2010: A 35-Year-Old Man with Adenocarcinoma of the Cecum |
| PMC3695728__F2 | Exploring mechanisms of FGF signalling through the lens of structural biology |
| PMC3695741__F2 | Nicotine and Pathological Angiogenesis |
| PMC3695748__F6 | Schema of regulatory mechanisms of endothelial atherosusceptibility discussed in the text |
| PMC3695880__F1 | The wiring diagram of the UPR model |
| PMC3696504__F1 | Relationship between metabolism and the autophagy machinery during the innate immune response |
| PMC3696549__F10 | Reciprocal regulation by TLR4 and TGFB in tumor-initiating stem-like cells |
| PMC3696550__F6 | Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia |
| PMC3696556__F4 | CD4+ follicular helper T cell infiltration predicts breast cancer survival |
| PMC3696556__F5 | CD4+ follicular helper T cell infiltration predicts breast cancer survival |
| PMC3696572__F1 | Linking MLL and the HGF-MET signaling pathway in liver cancer |
| PMC3696647__F7 | Schematic diagram for HIF-1A functions in cap-dependent translation of selective mRNAs, cell proliferation, and tumorsphere growth of cancer cells in low O2 environment |
| PMC3696710__F1 | Constitutive components and the transduced mechanisms of Hh signaling pathway |
| PMC3696710__F2 | Different models of Hh signaling pathway activation in cancer |
| PMC3696739__F3 | Parathyroid Hormone-Related Protein Specifies the Mammary Mesenchyme and Regulates Embryonic Mammary Development |
| PMC3696796__F5 | Schematic depiction of LB-205 effects on NGF stimulated pathways |
| PMC3697124__F3 | Antibiotics doxycycline and minocycline inhibit inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi |
| PMC3697618__F7 | Diagram illustrating the phagocytic signaling pathway initiated by TLR4-linked JAK2 activation during the internalization of B |
| PMC3697769__F2 | Signaling pathways activated in cord blood-derived CD34pos hematopoietic progenitor cells (upper panel) and in erythroblasts at day 6 of differentiation (erythroblasts, lower panel) |
| PMC3697783__F8 | Wnt signaling pathway |
| PMC3697894__F1 | Notch signaling pathway |
| PMC3697962__F2 | Insulin-like signaling pathway |
| PMC3697968__F5 | Model of DAF-2/IGFR pathway regulation by DPY-21 |
| PMC3698421__F10 | Schematic presentation of the Wnt signaling pathway |
| PMC3698571__F2 | Advances in targeting cell surface signalling molecules for immune modulation |
| PMC3698976__F2 | Methionine metabolism: transmethylation pathway |
| PMC3699383__F1 | Apoptosis pathways |
| PMC3699421__F2 | Reactivation of HIV-1 transcriptional latency |
| PMC3700115__F7 | Known and novel roles of the p38-MK2/3 signaling pathway in cross-striated muscles |
| PMC3700727__F1 | The Aryl Hydrocarbon Receptor: A Novel Target for Immunomodulation in Organ Transplantation |
| PMC3700945__F5 | Pathway detail for the IPN: Mucus Hypersecretion model.Notes: The Mucus Hypersecretion model contains signaling detail from four main pathways known to induce airway MUC5AC production |
| PMC3701121__F3 | Angiogenesis signaling pathways in epilepsy |
| PMC3701138__F1 | Main branches ofWnt signalling pathways in neuronal development |
| PMC3701226__F2 | Signaling pathways triggered by TCR and CD28 engagement |
| PMC3701522__F1 | Wnt signalling pathways implicated in diabetic nephropathy |
| PMC3701595__F8 | Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes |
| PMC3701596__F3 | Sleep specific effects on protein processing and the unfolded protein response |
| PMC3701598__F10 | Proteomic Profiling of Rabbit Embryonic Stem Cells Derived from Parthenotes and Fertilized Embryos |
| PMC3701722__F1 | Autophagy and endocrine resistance in breast cancer |
| PMC3701867__F1 | Scheme depicting the interactive roles of interferon, Trim, and Socs molecules regulating the innate response in SjS-susceptible C57BL/6.NOD-Aec1Aec2 mice |
| PMC3702218__F2 | New model for phrenic long-term facilitation with multiple signaling pathways |
| PMC3702256__F1 | Pathview: an R/Bioconductor package for pathway-based data integration and visualization |
| PMC3702279__F5 | Schematic diagram illustrating miR-185 and ATR function in radiation response |
| PMC3702291__F7 | Schematic model of signaling pathways in salinomycin-induced cell growth inhibition and apoptosis |
| PMC3702532__F7 | RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation |
| PMC3702532__F8 | RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation |
| PMC3702632__F7 | TLR4 and chemokine receptor crosstalk |
| PMC3703119__F5 | Schematic representation of the pathogenetic mechanism of AD copper phenotype |
| PMC3703147__F1 | Ubiquitination-mediated regulation of interferon responses |
| PMC3703268__F6 | Network view of TGF-beta signaling pathway alterations in colorectal and ovarian cancer |
| PMC3703418__F2 | Cellular mechanisms of BBR in reverting dysfunction in NAFLD |
| PMC3703460__F3 | Signaling Pathways That Control mRNA Turnover |
| PMC3703460__F4 | Signaling Pathways That Control mRNA Turnover |
| PMC3703486__F8 | Resveratrol enhances exercise training responses in rats selectively bred for high running performance |
| PMC3703536__F1 | Highlights of 10 years of immunology in Nature Reviews Immunology |
| PMC3703536__F5 | Highlights of 10 years of immunology in Nature Reviews Immunology |
| PMC3703549__F8 | Ang II activates the Notch1/Snail signaling, which is responsible for the pathogenesis of proteinuria in diabetic nephropathy |
| PMC3703662__F6 | Proposed model for NV-128-induced casapase-independent cell death in OCSCs |
| PMC3703753__F2 | Impact of Subarachnoid Hemorrhage on Parenchymal Arteriolar Function. |
| PMC3704172__F3 | miR-181b and miR-146a induced in CAFs are involved in the regulation of the NFKB signaling pathway |
| PMC3704221__F1 | miRNA biogenesis pathway |
| PMC3704444__F1 | Interaction between quality control systems for ER protein folding and RNA biogenesis |
| PMC3705163__F8 | Schematic model indicating proposed mechanisms by which mutant p53 GOF induces EMT |
| PMC3705329__F1 | SMAD/BMP pathway in hepatocytes |
| PMC3705551__F2 | Major catabolic and anabolic pathways in mammalian cells |
| PMC3705552__F2 | TIR8/SIGIRR, a negative regulatory receptor of ILR and TLR signaling |
| PMC3705591__F2 | Common signaling pathway for Toll/IL-1R (TIR) family members |
| PMC3705604__F1 | Influence of glycans and glycan-binding proteins in death receptor signaling and function |
| PMC3705708__F1 | Hedgehog Signal Transduction Network |
| PMC3705986__F7 | Schematic diagram that describes neuroprotective effects of SUL against ABeta-induced oxidative cell death in AD |
| PMC3705993__F1 | LRP5, LRP6 and LRP4 are important components of the Wnt/Beta-catenin signaling pathway |
| PMC3706396__F6 | S100A8/A9 (Calprotectin) Negatively Regulates G2/M Cell Cycle Progression and Growth of Squamous Cell Carcinoma |
| PMC3706439__F2 | Fermentation of Xylose Causes Inefficient Metabolic State Due to Carbon/Energy Starvation and Reduced Glycolytic Flux in Recombinant Industrial Saccharomyces cerevisiae |
| PMC3706484__F5 | Xenogeneic-Free Protocol for Isolation and Expansion of Human Adipose Stem Cells for Clinical Uses |
| PMC3706521__F3 | Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation |
| PMC3706521__F4 | Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation |
| PMC3706566__F6 | Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization |
| PMC3706794__F8 | Proposed mechanism demonstrating the interplay of heme oxygenase 1 (HO-1) and the Wnt canonical pathway in the modulation of adipogenesis in mesenchymal stem cells (MSC)-derived adipocytes |
| PMC3706831__F5 | DMGs in the KEGG 'Toll-like receptor signaling' pathway |
| PMC3706840__F8 | PRL-Dependent Tyrosyl Phosphorylated PAK1 and 3D Collagen IV Regulate MMP-1 and MMP-3 Production and Invasion via MAPK Pathways Schematic representation of the proposed working model |
| PMC3706856__F2 | The Effect of Curcumin on Breast Cancer Cells. |
| PMC3707302__F3 | Immunological synapse: the gateway to the HIV reservoir |
| PMC3707373__F1 | Regulation of Th9-Type Pulmonary Immune Responses. A New Role for COX-2 |
| PMC3707615__F5 | Encoding and Decoding Cellular Information through Signaling Dynamics |
| PMC3707630__F7 | CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex. |
| PMC3707895__F6 | NGF-Induced Cell Differentiation and Gene Activation Is Mediated by Integrative Nuclear FGFR1 Signaling (INFS) |
| PMC3707916__F5 | Altered Protein Networks and Cellular Pathways in Severe West Nile Disease in Mice |
| PMC3707951__F3 | Proposed intracellular effects of S100A1, S100A4, and S100A8/S100A9 |
| PMC3707951__F4 | S100A8 induction in macrophages |
| PMC3708179__F8 | Enrichment of hyper- and hypophosphorylated peptides in the ERK/MAPK signaling pathway in the phosphoproteome of murine liver on treatment with high-fat versus low-fat diet |
| PMC3708280__F1 | A simplified scheme of signaling pathways and cellular events involved in embryonic skeletal muscle formation |
| PMC3708280__F3 | Molecular background of major signaling pathways responsible for proper development of muscles and muscle stem cells in normal tissues and tissues affected by laminopathy |
| PMC3708286__F2 | Signaling pathways that relate disturbed polycystin-mediated Ca2+signaling to cell proliferation |
| PMC3708584__F3 | 'ErbB signalling' and 'TGFB pathway' in the canonical pathway |
| PMC3708595__F4 | Mutational Landscape of Adenoid Cystic Carcinoma |
| PMC3708799__F2 | PTEN in Beta-Cell Growth |
| PMC3708893__F5 | Oral Neutrophil Transcriptome Changes Result in a Pro-Survival Phenotype in Periodontal Diseases |
| PMC3709125__F1 | Gene regulatory networks in mammalian sex determination |
| PMC3709248__F4 | Nitr9L-Dap12 activation of cytotoxic cells |
| PMC3709411__F1 | Illustration of important relationships between metabolome, proteome, and genome in cancerous cells |
| PMC3709783__F6 | UV-induced cyclobutane dimers- structure (A) and repair by the Nucleotide Excision DNA Repair (NER) pathway (B) |
| PMC3709966__F4 | HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis |
| PMC3710315__F2 | Identification of STAT target genes in adipocytes |
| PMC3710321__F1 | Regulation of STATs by polycystin-1 and their role in polycystic kidney disease |
| PMC3710591__F7 | Cellular protective response to MeHg through the Keap1-Nrf2 system |
| PMC3710993__F1 | Energy status of cells modulating cell signaling and mitochondrial function |
| PMC3711035__F5 | The role of Wnt7a-induced hsa-miR29b expression in NSCLC proliferation |
| PMC3711071__F1 | Function and regulation of AMPK leading to tumor suppression |
| PMC3711139__F1 | Pyrrolo[3,2-d]pyrimidine Syntheses |
| PMC371122__F7 | Signaling pathway of UCP1 transcription in brown fat |
| PMC3711358__F9 | Diagram of the signal transduction pathway regulating stomatal development.Stages of stomatal development are given at the bottom of the figure |
| PMC3711381__F1 | ERK pathway, its upstream activators and downstream targets |
| PMC3711381__F3 | Htt affects ERK signaling in multiple ways |
| PMC3711692__F5 | Staufen-mediated mRNA decay |
| PMC3711797__F4 | Mathematical model of type I IFN signaling pathway |
| PMC3712008__F2 | Subnetwork representation of protein interactions based on 78 mutated genes in 602 breast cancers []-[] |
| PMC3712008__F3 | Hypothetical representation of opposite downstream effects of two signaling pathways on the G1 phase of the cell cycle in a breast tumor-initiating cell |
| PMC3712028__F7 | Model for the mechanism of regulation of glucose metabolism in muscle and liver by leptin in the VMH |
| PMC3712043__F1 | Activation of the IRS signaling cascade pathways |
| PMC3712052__F1 | Analysis strategy (-) to identify the putative regulatory effect of GWAS candidate () on FRMD3 regulation (), linking the gene to transcriptional regulation of the BMP pathway (-) and DN and suggesting a hypothetical regulatory model () |
| PMC3712075__F6 | Schematic diagram showing the involvement of CPT1C and ceramides in the hypothalamic ghrelin signaling pathway |
| PMC3712086__F5 | Diagram illustrating the signaling mechanism of how CARD9 may be inhibiting apoptosis from TNF-alpha |
| PMC3712126__F2 | Bcl-2 family-regulated pathway and phenotypes in Bcl-2 knockout mice after status epilepticus |
| PMC3712188__F2 | Inducing autophagy by inhibiting the mTOR pathway.mTOR is a downstream effector of the class I phosphoinositol 3-kinase (PI3K) pathway |
| PMC3712188__F3 | Autophagy and polyglutamine diseases. |
| PMC3712543__F4 | Somatic variations in genes encoding proteins of the KEGG "Melanoma" signaling pathway |
| PMC3712618__F4 | Putative PGC-1-mediated mechanism of cancer-induced skeletal muscle wasting |
| PMC3712714__F1 | Interaction between the vitamin D endocrine system and the inflammatory signaling pathway in control of cancer cell growth (for details, see [,]) |
| PMC3712731__F4 | Display of wild-type and disease pathway diagrams |
| PMC3712869__F4 | Smooth Muscle Differentiation and Patterning in the Urinary Bladder |
| PMC3713213__F7 | Signaling pathways showing mechanisms involved in the protective effects of cardiac-specific CYP2J2 transgenic mice subjected to diabetic stress |
| PMC3713357__F1 | Possible pathways for growth factor mediated tumorigenesis |
| PMC3713495__F4 | EZH2 promotes E2F driven SCLC tumorigenesis through modulation of apoptosis and cell cycle regulation |
| PMC3713637__F4 | Transcriptional regulation network centered on SP1 involves many genes of interest from pathways enriched in memory impairment |
| PMC3713775__F1 | MicroRNA and Signal Transduction Pathways in Tumor Radiation Response |
| PMC3713775__F2 | MicroRNA and Signal Transduction Pathways in Tumor Radiation Response |
| PMC3713848__F9 | Proposed model for the integration of primary afferent, mast cell and sympathetic systems in supporting CRPS-related nociception |
| PMC3714203__F2 | DR4 and DR5 Agonistic mAb-induced Apoptosis: Regulation of TRAIL/Apo2L Resistance by HDACi |
| PMC3714205__F2 | Signaling via by cytokines and growth factors and its negative regulation by SOCS proteins |
| PMC3714263__F6 | ERK Positive Feedback Regulates a Widespread Network of Tyrosine Phosphorylation Sites across Canonical T Cell Signaling and Actin Cytoskeletal Proteins in Jurkat T Cells |
| PMC3714282__F1 | Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder - Possible Role for Methoxyindole Pathway |
| PMC3714559__F1 | Model for resolving transcription-blocking lesions |
| PMC3714590__F5 | Known and Predicted Interactions between the Products of the 352 Genes Bound Preferentially by Pol II in Neuroepithelial CellsAnalysis was performed using STRING with a medium confidence score of 0.4 and all interaction methods available |
| PMC3715049__F1 | Proteomic strategies for studying the mechanism of miRNA processing and miRNA-mediated translation repression |
| PMC3715061__F1 | Hedgehog signaling, vismodegib action, and acquired resistance |
| PMC3715494__F2 | A Lover and a Fighter: The Genome Sequence of an Entomopathogenic Nematode Heterorhabditis bacteriophora |
| PMC3715701__F1 | Myosin 1c in cellular signaling pathways |
| PMC3715730__F3 | Ingenuity pathway analysis (IPA) of Interferon Signaling Pathway of genes differentially expressed in the bronchial epithelial cells exposed to Alternaria alternata spores |
| PMC3716523__F4 | TGFB signaling pathway |
| PMC3716752__F1 | Toward understanding the genetics of regulatory T cells in ovarian cancer |
| PMC3717064__F1 | NK cell activating and inhibitory receptors and their downstream signaling molecules |
| PMC3717195__F1 | DNA repair systems |
| PMC3717758__F3 | Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease |
| PMC3717793__F1 | Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2 |
| PMC3717794__F1 | Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway |
| PMC3717794__F2 | Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway |
| PMC3717800__F7 | Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma |
| PMC3717802__F6 | Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer |
| PMC3717870__F4 | Analysis of gene transcription in response to an acute bout of exercise identifies dysregulation of SMAD, CREB, and HDAC activity in LRT |
| PMC3717945__F3 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance |
| PMC3718392__F1 | mTORC1 signaling |
| PMC3718392__F2 | Targeting of PI3K/mTORC1 signaling in hamartoma syndromes |
| PMC3718675__F3 | Axis of ageing: telomeres, p53 and mitochondria |
| PMC3718996__F8 | Graphs showing the different regulation of glioma cell signaling when cells were cultured on biomatrix, myelin and unmyelinated tissue (retina) |
| PMC3719176__F3 | WT transcriptome data overlaid on selected metabolic pathways |
| PMC3719407__F4 | Functional link between the BMP system and GnRH-induced FSH transcription |
| PMC3720155__F2 | Sketch of the relationship between IGF signalling, the PI3K pathway and androgen responses in the prostate |
| PMC3720582__F1 | Comprehensive Hedgehog Signaling Pathway |
| PMC3720582__F2 | Structural and Logical Analysis of a Comprehensive Hedgehog Signaling Pathway to Identify Alternative Drug Targets for Glioma, Colon and Pancreatic Cancer |
| PMC3720596__F1 | NRAS mutant melanoma - undrugable? |
| PMC3720640__F3 | Anti-Epidermal Growth Factor Receptor Therapy in Head and Neck Squamous Cell Carcinoma: Focus on Potential Molecular Mechanisms of Drug Resistance. |
| PMC3720736__F2 | Activation of Wnt/Beta-Catenin Pathway in Monocytes Derived from Chronic Kidney Disease Patients |
| PMC3720830__F7 | Cytochrome P450 1A1 Regulates Breast Cancer Cell Proliferation and Survival |
| PMC3720859__F4 | Capacity of Aptamers to Trigger Immune Activation in Human Blood |
| PMC3721034__F2 | MDM2-p53 pathway revisited |
| PMC3721034__F5 | MDM2-p53 pathway revisited |
| PMC3721080__F6 | Spatio-temporal analysis of type 2 diabetes mellitus based on differential expression networks |
| PMC3721230__F1 | Mechanisms of action of lipopolysaccharide (LPS) as a sepsis inducer |
| PMC3721281__F2 | Asparagine-linked glycosylation pathway |
| PMC3721286__F3 | Simplified scheme presenting multiple feedback loops in the EGFR pathway |
| PMC3721368__F1 | Schematic depicting the canonical and noncanonical TGFB signaling systems coupled to EMT in MECs |
| PMC3721632__F1 | Th17 cell based vaccines in mucosal immunity |
| PMC3721730__F1 | Intrinsic and ER pathways of apoptosis |
| PMC3721730__F2 | TRAIL-mediated extrinsic pathway of apoptosis |
| PMC3721836__F9 | Simplified model of Rac1 signaling and function in learning-induced adult neurogenesis |
| PMC3722174__F8 | Primary Respiratory Chain Disease Causes Tissue-Specific Dysregulation of the Global Transcriptome and Nutrient-Sensing Signaling Network |
| PMC3722318__F1 | Autophagy master regulator TFEB induces clearance of toxic SERPINA1/Alpha-1-antitrypsin polymers |
| PMC3722362__F3 | Regulation of Iron Absorption in Hemoglobinopathies |
| PMC3722447__F1 | Defects within components of the ECM and the TGFB signaling pathway leading to various HCTD |
| PMC3722486__F9 | Proposed role of Foxg1 in CM development |
| PMC3722525__F7 | Antigen processing and presentation pathway and the cell cycle pathway |
| PMC3722917__F3 | Naive CD8+ T cells differentiate into cytotoxic T lymphocytes (CTLs) on exposure to antigens |
| PMC3722958__F1 | P38 MAPK in the induction of pemphigus vulgaris (PV) |
| PMC3722958__F2 | The suggested interplay between natural killer (NK), CD4+ T, B cells, and polymorphonuclear cells (PMN) during pemphigus pathogenesis [] |
| PMC3723114__F1 | Canonical and noncanonical TGFB signaling systems activated during mammary tumorigenesis |
| PMC3723115__F2 | Canonical TGFB signaling within distinct cell types located in tumor microenvironments |
| PMC3723343__F3 | Cripto/GRP78 modulation of the TGFB pathway in development and oncogenesis |
| PMC3723562__F7 | Polyethyleneimine Mediated DNA Transfection in Schistosome Parasites and Regulation of the WNT Signaling Pathway by a Dominant-Negative SmMef2 |
| PMC3724057__F7 | MOMA analysis identifies double-gene knockouts in primary metabolism that funnel carbon toward DHA |
| PMC3724215__F1 | IGF pathway |
| PMC3724248__F1 | MicroRNA pathway is universal to all mammalian miRNAs |
| PMC3724356__F2 | Molecular events in cholangiocarcinogenesis |
| PMC3724399__F1 | PI3K/Akt/mTOR pathway |
| PMC3724417__F2 | Signaling Mechanisms in Mammalian Myoblast Fusion |
| PMC3724517__F4 | Pathway analysis of differentially expressed genes in RAF265 responding versus nonresponding tumors |
| PMC3724648__F6 | Model showing the effects of PP2A in SLE T-cells |
| PMC3724785__F7 | Lysine-Specific Demethylase 1 (LSD1/KDM1A) Contributes to Colorectal Tumorigenesis via Activation of the Wnt/Î’-Catenin Pathway by Down-Regulating Dickkopf-1 (DKK1) |
| PMC3724874__F7 | Propyl-2-(8-(3,4-Difluorobenzyl)-2',5'-Dioxo-8-Azaspiro[Bicyclo[3.2.1] Octane-3,4'-Imidazolidine]-1'-yl) Acetate Induces Apoptosis in Human Leukemia Cells through Mitochondrial Pathway following Cell Cycle Arrest |
| PMC3724896__F4 | Differentiated Neuroprogenitor Cells Incubated with Human or Canine Adenovirus, or Lentiviral Vectors Have Distinct Transcriptome Profiles |
| PMC3724940__F5 | Transcriptomic Analysis of Insulin-Sensitive Tissues from Anti-Diabetic Drug Treated ZDF Rats, a T2DM Animal Model |
| PMC3725129__F1 | Proposed B[a]P metabolic pathways and their representative metabolites |
| PMC3725164__F1 | TGFB signaling pathway |
| PMC3725503__F1 | Network of the mechanistic Target of Rapamycin (mTOR) signaling pathway |
| PMC3725543__F6 | FAK-mediated growth of C2C12 cells in response to IGF-I |
| PMC3725690__F6 | Working model for the NOX dependence of TNFA production by the liver following I/R injury |
| PMC3725758__F2 | Neurofibromatosis Type 2 Protein, NF2: An uncoventional cell cycle regulator |
| PMC3725781__F1 | Genetic and molecular control of Osterix in skeletal formation |
| PMC3726008__F5 | Dose-dependent MeHg-induced gene expression alterations within the Wnt-signaling pathway |
| PMC3726197__F1 | Signaling axis exploited in the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) mutant mouse model of prostate tumorigenesis |
| PMC3726314__F6 | Toll-Like Receptor 4-Myeloid Differentiation Factor 88 Signaling Contributes to Ventilator-induced Lung Injury in Mice |
| PMC3726361__F4 | Focal adhesion signaling pathway highlighting those genes that are differentially expressed compared to untreated control ovaries and identifying by color the treatment group(s) from which the differentially expressed genes came |
| PMC3726398__F2 | Reconstructing the interactions among different modules of the MAPK pathway |
| PMC3726443__F6 | Full Transcriptome Analysis of Early Dorsoventral Patterning in Zebrafish |
| PMC3726753__F2 | Morphoproteomic Profiling of the Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Desmoplastic Small Round Cell Tumor (EWS/WT1), Ewing's Sarcoma (EWS/FLI1) and Wilms' Tumor(WT1) |
| PMC3726942__F10 | Roles of the autocrine angiotensin system in ER stress-induced apoptosis of alveolar epithelial cells |
| PMC3726950__F2 | Regulation of autophagy pathways and targets for modulating autophagy by drugs/compounds |
| PMC3726964__F3 | Regulation of the EMT Pathway and Tec kinase signaling in Calu-6 compared to U1752 |
| PMC3727154__F1 | Immunomodulatory functions of type I interferons |
| PMC3727840__F2 | TGFB in bone metastasis: novel therapeutic perspectives |
| PMC3727904__F2 | PATHWAYS IN MICROBE-INDUCED OBESITY |
| PMC3728089__F5 | Cholinergic anti-inflammatory pathway |
| PMC3728221__F8 | Working model for the synergistic effect of TPL and ATF on tumour cells |
| PMC3728269__F1 | Signaling pathways in melanoma.Notes: Oncoprotein Ras activates both the MAPK and PI3K/Akt survival pathways |
| PMC3728701__F1 | Musashi1 (Msi1)-dependent activation of Wnt and Notch pathways as well as of proliferation in the intestinal progenitors |
| PMC3728801__F1 | Canonical and non-canonical NFKB pathways |
| PMC3728834__F7 | Proposed model illustrating the effects of reduced TH in thyroid cancer development in ThrbPV/PV-PTU mice |
| PMC3729218__F4 | Mutations causing susceptibility to intestinal inflammation |
| PMC3729336__F1 | Schematic overview of the kynurenine (KYN) pathway |
| PMC3729625__F2 | Cellular Metabolic and Autophagic Pathways: Traffic Control by Redox Signaling |
| PMC3729625__F3 | Cellular Metabolic and Autophagic Pathways: Traffic Control by Redox Signaling |
| PMC3729625__F5 | Cellular Metabolic and Autophagic Pathways: Traffic Control by Redox Signaling. |
| PMC3729906__F1 | Molecules examined by immunohistochemistry |
| PMC3729926__F6 | Aldose Reductase Inhibition Enhances TRAIL-Induced Human Colon Cancer Cell Apoptosis through AKT/FOXO3a-dependent upregulation of Death Receptors |
| PMC3729982__F1 | Flowering time genes recently identified as targets of selection in crop species |
| PMC3730126__F1 | Molecular mechanisms of cellular insulin resistance in muscle and liver |
| PMC3730324__F1 | HIFs are involved in crucial aspects of tumor progression and metastasis in sarcomas |
| PMC3730337__F1 | HDACi and DNMTi target the MM cell |
| PMC3730427__F8 | Glucose deprivation in cancer cells activates UPR following HBP flux reduction |
| PMC3730428__F8 | Schematic diagram summarizing the key findings |
| PMC3730487__F2 | Two mechanisms of phase II xenobiotic-metabolizing enzyme induction by phase II inducers |
| PMC3730684__F1 | The Smad-dependent TGFB signalling pathway upon stimulation with TGFB and BMP |
| PMC3730813__F1 | Pattern Recognition Receptors in Intestinal Inflammation |
| PMC3730813__F2 | Pattern Recognition Receptors in Intestinal Inflammation |
| PMC3731064__F2 | Chromatin and the genome integrity network |
| PMC3731316__F1 | Gene Network Analysis of Candidate Loci for Human Anorectal Malformations |
| PMC3731320__F1 | Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway |
| PMC3731360__F6 | Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia |
| PMC3731517__F6 | Hepatic cholesterol synthesis and catabolism enzymes, uptake receptors, BA transport systems, phase II detoxification enzymes, and nuclear receptors investigated in this study |
| PMC3731598__F1 | An immune synapse and downstream events |
| PMC3731808__F6 | Comparison of gene expression changes in human bladder cancer and our mouse model based on KEGG pathway analysis |
| PMC3731936__F5 | Sequestration-induced loss of protein C receptors links coagulation, inflammation, and endothelial permeability |
| PMC3732055__F1 | PAM and Copper - a Gene/Nutrient Interaction Critical to Nervous System Function |
| PMC3732412__F3 | KEGG pathway map for genes in the three modules |
| PMC3732459__F2 | Innate Immune Responses in Hepatitis C Virus Infection |
| PMC3732459__F3 | Innate Immune Responses in Hepatitis C Virus Infection |
| PMC3732476__F2 | Notch signaling pathway |
| PMC3732559__F5 | HMGB1 in Cancer: Good, Bad, or Both? |
| PMC3733021__F1 | Schematic diagram of the ZFN, TALEN, and CRISPR/Cas9 genome editing tools |
| PMC3733085__F2 | Simplified scheme of the pathways of complement activation |
| PMC3733118__F2 | Genes of innate immunity and the biological response to inhaled ozone |
| PMC3733232__F1 | TGFBeta-mediated signaling and transcriptional regulation in pancreatic development and cancer |
| PMC3733265__F1 | Mimicking the BH3 domain to kill cancer cells |
| PMC3733450__F2 | Kaposi's Sarcoma-Associated Herpesvirus G Protein Coupled Receptor: Lessons on Dysregulated Angiogenesis from a Viral Oncogene |
| PMC3733544__F7 | FA/BRCA DNA damage response pathway |
| PMC3733582__F3 | Pathway Linker Results for AChE and BChE |
| PMC3733802__F2 | Prioritizing Disease Candidate Proteins in Cardiomyopathy-Specific Protein-Protein Interaction Networks Based on "Guilt by Association" Analysis |
| PMC3733962__F1 | Proteomic Analysis of Signaling Network Regulation in Renal Cell Carcinomas with Differential Hypoxia-Inducible Factor-2A Expression |
| PMC3734089__F1 | Macrophages in pancreatic cancer initiation and progression |
| PMC3734218__F1 | Roles of Genetic Polymorphisms in the Folate Pathway in Childhood Acute Lymphoblastic Leukemia Evaluated by Bayesian Relevance and Effect Size Analysis |
| PMC3734242__F8 | Role of PTPA in the Destruction of Periodontal Connective Tissues |
| PMC3734370__F1 | Regulated secretory pathway of a model neuroendocrine cell |
| PMC3734592__F5 | Ingenuity analysis of representative accumulated proteins in response to inactivation of CRL/SCF system |
| PMC3734825__F7 | Upregulation of HSP70 and the phosphorylation of STAT1 induced by bortezomib (BTZ) decrease the cytotoxic activity against ovarian cancer cells |
| PMC3734838__F6 | Schematic illustration delineating the role of the AKT/Foxo3a/Bim pathway in selenite-induced apoptosis of CRC cells |
| PMC3734905__F2 | Germline syndromes associated with the Ras signaling pathway.Schematic diagram showing the GM-CSF receptor spanning the phospholipid bilayer |
| PMC3734934__F6 | Disruption of mindin exacerbates cardiac hypertrophy and fibrosis |
| PMC3735083__F1 | HIF-1A regulation in cancer |
| PMC3735202__F3 | Schematic diagram showing the Ras signalling pathway and its linkage to the GTPase cellular motility axis (Reproduced with permission from) |
| PMC3735683__F3 | From Genetics of Inflammatory Bowel Disease Towards Mechanistic Insights |
| PMC3735686__F1 | Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma |
| PMC3735707__F3 | Maternal factors required for oocyte developmental competence in mice |
| PMC3735707__F6 | Maternal factors required for oocyte developmental competence in mice |
| PMC3735826__F5 | miRNA-548c: a specific signature in circulating PBMCs from dilated cardiomyopathy patients |
| PMC3735949__F3 | Comparison of gene expression in RAW264.7 (RAW) and TGEM cells treated with KLA for the TLR4 signaling pathway |
| PMC3735949__F4 | Comparison of the gene expression and eicosanoid metabolite changes in RAW264.7 (RAW) and TGEM cells treated with KLA is shown for the arachidonic acid metabolism pathway |
| PMC3735949__F5 | A comparison of gene expression and lipid metabolite changes in RAW264.7 (RAW) and TGEM cells treated with KLA is shown for the sterol biosynthesis pathway |
| PMC3735949__F6 | Changes in the genes and processes related to mitochondrial metabolism in RAW264.7 and TGEM cells treated with KLA |
| PMC3735985__F1 | Simplified schematic representation of the insulin and TOR signaling pathways as they have been described in mammals and for which orthologous components have been described in D |
| PMC3736320__F1 | Déjà vu: EGF receptors drive resistance to BRAF inhibitors |
| PMC3736482__F3 | Associated intracellular cascades to physiopathology of vascular remodeling |
| PMC3736507__F2 | Schematic diagram showing that cartilage matrix homeostasis is adjusted dynamically by TGFB signaling pathway |
| PMC3736525__F3 | Lycopene induces cell-cycle arrest and apoptosis |
| PMC3736525__F4 | Lycopene inhibits theWnt/Beta-catenin pathway |
| PMC3736540__F1 | Computational Model of Lipopolysaccharide-Induced Nuclear Factor Kappa B Activation: A Key Signalling Pathway in Infection-Induced Preterm Labour |
| PMC3736724__F1 | Tyrosine kinase (TYK) targeting growth factor and proliferation pathways |
| PMC3736728__F2 | Folate, Alcohol, and Liver Disease |
| PMC3737169__F2 | MTX cellular pathway |
| PMC3737294__F1 | Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance |
| PMC3737373__F9 | RNAi Mediated Tiam1 Gene Knockdown Inhibits Invasion of Retinoblastoma |
| PMC3737462__F2 | Accumulation of monocytes/macrophages in adipose tissue and liver, and activation in the tissues |
| PMC3737553__F6 | Our proposed model for two distinct pathways in ICL-induced ATR signaling |
| PMC3737722__F7 | Model of cell-surface regulation of HH signaling |
| PMC3737723__F8 | Model of the Prdm1a gene regulatory network for NCC specification |
| PMC3738179__F1 | Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling |
| PMC3738179__F2 | Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling |
| PMC3738954__F4 | Key signaling pathways modulated by WNV infection |
| PMC3739039__F3 | Integrated "omic" analysis reveals global metabolic changes |
| PMC3739146__F7 | NAC protects against Cd-induced germ cell apoptosis by inhibiting UPR signalling in the testes |
| PMC3739200__F1 | Three important components in the regeneration of the cavernous nerve: brain-derived neurotrophic factor, vascular endothelial growth factor and the JAK/STAT signaling pathway. |
| PMC3739348__F6 | Expression of some genes related to the cell cycle and apoptosis were significantly changed after LM23 knockdown, as shown by microarray analysis |
| PMC3739939__F4 | Pathway analysis showing integration between signaling pathways, transcription factors, and adhesion genes |
| PMC3740204__F2 | Angiogenesis pathway of FAK, EZH2 and Dll4/Notch in cancer-associated endothelial cells |
| PMC3740364__F1 | Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways |
| PMC3740688__F3 | Pathogenic Mechanisms in Type 1 Diabetes: The Islet is Both Target and Driver of Disease |
| PMC3740690__F1 | Protein Tyrosine Phosphatases and Type 1 Diabetes: Genetic and Functional Implications of PTPN2 and PTPN22 |
| PMC3741132__F1 | Application of Artificial Neural Networks to Investigate One-Carbon Metabolism in Alzheimer's Disease and Healthy Matched Individuals |
| PMC3741135__F9 | Sirt1 Inhibits Akt2-Mediated Porcine Adipogenesis Potentially by Direct Protein-Protein Interaction |
| PMC3741150__F8 | Mitochondrial Transcription Factor A, an Endogenous Danger Signal, Promotes TNFA Release via RAGE- and TLR9-Responsive Plasmacytoid Dendritic Cells |
| PMC3741284__F2 | Hepatitis C Virus Induced miR200c Down Modulates FAP-1, a Negative Regulator of Src Signaling and Promotes Hepatic Fibrosis |
| PMC3741305__F4 | EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway |
| PMC3741439__F1 | The catecholamine biosynthetic pathway |
| PMC3741506__F1 | ASC-mediated switch between pyroptosis and apoptosis: intracellular pathogens and their products lead to activation of the ASC-dependent inflammasome |
| PMC3742001__F7 | Schematic diagram summarizing the signaling pathways relevant to this study |
| PMC3742039__F3 | Gene expression in keratinocytes related to IL-1 signaling |
| PMC3742180__F8 | Comparison of Cellular Uptake and Inflammatory Response via Toll-Like Receptor 4 to Lipopolysaccharide and Titanium Dioxide Nanoparticles. |
| PMC3742223__F1 | Ageing-dependent decline in thyroid activity, leading to compensatory increases in cellular D1 activity and thyroid hormone metabolites that may, through non-genomic pathways, be involved in amelioration of ageing related metabolic disturbances |
| PMC3742224__F3 | Structure of human cine-N-methyltransferase (GNMT) gene in connection with scheme of sarcosine genesis in biochemical pathway |
| PMC3742228__F2 | Schematic overview of Hedgehog signaling and rationale for combination therapy with (chemo)radiotherapy |
| PMC3742248__F2 | Role of miR-302 during human ESCs (hESC) neural differentiation |
| PMC3742302__F6 | Omics-Based Molecular Target and Biomarker Identification |
| PMC3742358__F3 | Pathway of nucleotide excision repair and translesion synthesis |
| PMC3742550__F3 | Intracellular 1-carbon metabolism (simplified), emphasizing pathways relevant to the text |
| PMC3742652__F4 | Proposed Twist2 involvment in ovarian cancer |
| PMC3742659__F2 | Learning and memory: an emergent property of cell motility |
| PMC3742697__F8 | Proposed model of Cr(VI)-induced carcinogenesis |
| PMC3742712__F2 | Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection |
| PMC3742868__F11 | Proposed scheme for the role of mTOR in p53-induced kidney cell injury |
| PMC3742913__F5 | Gene pathways revealed by comprehensive genomic profiling |
| PMC374303__F8 | The multiple mechanisms by which HSV-1 blocks cellular IFN-based defense systems |
| PMC3743078__F4 | New insights into the biological effects of anthrax toxins: linking cellular to organismal responses |
| PMC3743096__F4 | Signal integration by mTORC1 coordinates nutrient input with biosynthetic output |
| PMC3743157__F3 | RB1 pathway indicating genes with mutations in this series |
| PMC3743449__F4 | Classical example of NFKB is the heterodimer of p50 and p65 and the classical activation pathway entails the release from its association with an inhibitory molecule of the IKB family |
| PMC3743449__F5 | Illustration of the hypoxia-inducible factor (HIF) activation pathway, highlighting hydroxylation and acetylation of HIF-1A depending on cellular oxygen tension, that is, normoxia and hypoxia |
| PMC3743503__F8 | GeneGo pathway map translation regulation of eIF2 activity |
| PMC3743503__F9 | Evidence for indirect influence of kinases on tau phosphorylation |
| PMC3743775__F6 | Cis Association of Galectin-9 with Tim-3 Differentially Regulates IL-12/IL-23 Expressions in Monocytes via TLR Signaling |
| PMC3743959__F1 | Toll-Like Receptor (TLR)-Associated Sequence Variants and Prostate Cancer Risk among Men of African Descent. |
| PMC3744028__F9 | Summary of the proposed role of Pak1 in mediating stretch-induced CTGF upregulation |
| PMC3744088__F6 | Extent to which glutamate (GLU) is oxidized in astrocytes seems to increase particularly during higher glutamate concentrations |
| PMC3744227__F1 | Chemopreventive potential of natural compounds in head and neck cancer |
| PMC3744328__F1 | Sumoylation and regulation of cardiac gene expression |
| PMC3744367__F1 | mTOR couples cellular nutrient sensing to organismal metabolic homeostasis |
| PMC3744446__F1 | Past Visits Present: TCF/LEFs Partner with ATFs for Beta-Catenin-Independent Activity |
| PMC3744771__F1 | Inhibitory molecules and therapeutic targets within the Rhopathway |
| PMC3744802__F5 | Model of regulation of the length of D-loop extension by PCNA and choice of polymerase |
| PMC3744831__F2 | DDR-adapted model in meiotic silencing |
| PMC3744901__F9 | Regulation of RB/E2F pathway |
| PMC3745214__F1 | Targeting TGFB signaling in cancer |
| PMC3745214__F4 | Targeting TGFB signaling in cancer |
| PMC3745216__F3 | TGFB signalling pathway |
| PMC3745259__F1 | The hexosamine biosynthetic pathway provides the donor substrate for O-GlcNAcylation and other types of protein glycosylation |
| PMC3745259__F2 | O-GlcNAc is involved in the cellular stress response |
| PMC3745317__F1 | Eicosanoid biosynthetic pathway and its activation by RTK/GFR →ERK1/2 signaling |
| PMC3745370__F8 | High expression of the ppGalNAc-T13 gene enhances cancer metastasis by formation of trimeric Tn antigen |
| PMC3745713__F2 | Methionine-homocysteine and aromatase pathways and their involvement in 2-ME synthesis |
| PMC3745819__F1 | A CENTRAL ROLE FOR INDUCIBLE HEAT SHOCK PROTEIN 70 IN AUTOIMMUNE VITILIGO |
| PMC3745930__F5 | Roles of hnRNPs in the impaired granulocytic differentiation of BCR/ABL transformed myeloid progenitor cells |
| PMC3746082__F1 | Diabetes mellitus induced regulation of osteoblast |
| PMC3746082__F3 | Diabetes mellitus induced regulation of osteoclast |
| PMC3746082__F4 | Diabetes mellitus induced regulation of skeletal muscle |
| PMC3746496__F2 | PKM2 activity is controlled by a tight regulatory network at the transcriptional, proteomic and metabolic level |
| PMC3746560__F7 | TG2-containing adhesive/signaling complexes on the cell surface |
| PMC3746754__F2 | Iron metabolism in the eye, a review |
| PMC3747328__F1 | The role of K+ channels during cell cycle progression and proliferation |
| PMC3747383__F1 | PPARG transduction pathway |
| PMC3747497__F1 | FGF signalling: diverse roles during early vertebrate embryogenesis |
| PMC3747540__F1 | Emerging signaling pathways in hepatocellular carcinoma |
| PMC3747576__F6 | Urokinase pathway model |
| PMC3747619__F2 | Key reactions involved in the sphingolipid metabolic pathway |
| PMC3748035__F1 | Dynamic regulation of P2X4 receptors in microglia |
| PMC3748092__F8 | Cell Surface Glycan Alterations in Epithelial Mesenchymal Transition Process of Huh7 Hepatocellular Carcinoma Cell |
| PMC3748257__F2 | STAT signaling in mammary gland differentiation, cell survival and tumorigenesis |
| PMC3748736__F1 | Hippo pathway in Drosophila (a) and mammals (b) |
| PMC3748765__F1 | TCDD-induced CTLA-4 on AhR-Treg activating the tolerogenic IDO pathway and suppressing the acute GVH response |
| PMC3748992__F5 | Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma |
| PMC3749695__F8 | Cumulative scheme adapted from the data published in (, -, , , , , ) showing components of pathways implicated in regulating the life span in Drosophila and their interactions |
| PMC3749718__F7 | The putative steps in the redox signaling pathway leading to adaptive activation of transcription factors and upregulation of the expression of cytoprotective proteins following contractile activity in skeletal muscle |
| PMC3749846__F3 | Role of DMP1 and its future in lung cancer diagnostics |
| PMC3749870__F10 | CD25 and CD69 induction by A4B1 outside-in signalling requires TCR early signalling complex proteins |
| PMC3749885__F2 | Pim kinase targets and their roles in inflammation and cancer |
| PMC3750075__F1 | ACK1/TNK2, a non-receptor tyrosine kinase (NRTK), represents a paradigm of tyrosine kinase signaling that appears to be addictive in cancer cells [] |
| PMC3750319__F2 | Canonical, non-canonical and the atypical NFKB signaling pathway |
| PMC3750319__F5 | Crosstalk of the canonical NFKB pathway with other signaling processes |
| PMC3750403__F3 | BIOBASE-derived signaling network centered on p38 MAPK |
| PMC3750636__F1 | USP1 Domain structure and summary of the cellular functions of the USP1/UAF1 complex |
| PMC3751038__F2 | T-cell death during HIV-1 infection |
| PMC3751638__F3 | METH-regulated genes in METH-pretreated rats |
| PMC3751673__F3 | Ingenuity pathway analysis of the top-ranked network |
| PMC3751776__F2 | BTK signaling pathway |
| PMC3752265__F5 | Example of differences in use between glycolysis and the ED pathway by representative cells in our modeled population |
| PMC3752772__F2 | NFKB activation pathways triggered by TNF family signaling |
| PMC3752952__F1 | Pathomechanisms of LN outside the kidney |
| PMC3753040__F1 | Chromatin Recruitment of DNA repair proteins: Lessons from the Fanconi Anemia and Double Strand Break Repair Pathways |
| PMC3753466__F3 | Skp2/Cks1 is induced by the TNFA/NFKB signaling pathway in nephropathy |
| PMC3753467__F1 | IP3 instigates the activation and amplification of NFATc1 |
| PMC3753504__F28 | Influence of hepatocyte culture conditions on signaling and phenotype |
| PMC3753504__F39 | Activation of different death receptor signaling pathways depending on the culture conditions of hepatocytes |
| PMC3753703__F3 | Alterations within the TP53 and RB1/E2F3 pathways in high-grade bladder cancer |
| PMC3753830__F1 | Schematic overview of signalling pathways and drug targets currently under investigation in CML research |
| PMC3753831__F1 | ERK1/2-mediated regulation of the G1-S phase transition |
| PMC3753831__F2 | ERK1/2-mediated regulation of the BCL2 protein family |
| PMC3754142__F3 | Oncogenic and antiapoptotic functions of KSHV |
| PMC3754247__F2 | Oncometabolites: linking altered metabolism with cancer |
| PMC3754249__F2 | HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations |
| PMC3754249__F3 | HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations |
| PMC3754482__F6 | Glycocode model: 3-OST-5 and 3-OST-6 regulate distinct cell signaling pathways for ciliogenesis and cilia motility |
| PMC3754784__F1 | Toll-like receptor signaling in liver regeneration, fibrosis and carcinogenesis |
| PMC3755284__F1 | Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization |
| PMC3755464__F3 | Recombination-independent interstrand crosslink repair pathway in vertebrates |
| PMC3755473__F1 | Plasma Cells For Hire: Prior Experience Required |
| PMC3756172__F1 | Summary of AERD associated single nucleotide polymorphisms in the genes of immune response and arachidonate pathway |
| PMC3756346__F2 | Map of the molecular mechanisms of apoptosis [] |
| PMC3756375__F2 | Nerve growth factor (NGF) signaling in breast cancer cells |
| PMC3756396__F1 | Simplified scheme of the possible involvement of cAMP/PKA pathway in cancer |
| PMC3756518__F1 | Schematic of the simplified B-cell receptor (BCR) signaling pathway simulated in our Monte Carlo method |
| PMC3756614__F11 | Signaling pathways used by EGF to stimulate goblet cell proliferation |
| PMC3756827__F1 | Sirt3 deacetylation targets, and regulation of Sirt3 expression and activity |
| PMC3757148__F2 | Challenging macrophages with PAMPs such as LPS stimulates synthesis of pro-IL-1B and pro-IL-18 |
| PMC3757153__F2 | Treatment advances in neonatal neuroprotection and neurointensive care |
| PMC3757225__F7 | Mechanistic model of strain-induced fetal type II cell differentiation via integrin-TACE pathway |
| PMC3757331__F8 | Revisiting MPF activation |
| PMC3757373__F1 | Methionine metabolism in liver |
| PMC3757375__F1 | Signal Transduction Pathways controlled by the activation of epidermal growth factor receptors (EGFR) |
| PMC3757382__F1 | Modified Fearson and Volgenstein Model |
| PMC3757391__F1 | Maintainance of DNA Methylation |
| PMC3757404__F1 | Wnt/Beta-catenin Signaling Pathway |
| PMC3757426__F1 | Epidermal growth factor receptor (EGFR) crosstalk |
| PMC3757428__F2 | Growth factors mediated mTORC1 and mTORC2 activation |
| PMC3757681__F1 | Consequences of oxidative stress on proteins, the proteasomal system and transcription factors |
| PMC3757712__F3 | Crosstalk between the Nrf2 and NFKB pathways |
| PMC3757945__F3 | Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair |
| PMC3758473__F2 | Genetics of Mammalian Circadian Order and Disorder: Implications for Physiology and Disease |
| PMC3758473__F5 | The Genetics of Mammalian Circadian Order and Disorder: Implications for Physiology and Disease |
| PMC3758882__F1 | Normal complement activation cascade and its regulation |
| PMC3759013__F1 | Melanoma: New Insights and New Therapies |
| PMC3759014__F1 | The main constituents of the Sonic Hedgehog (SHH) pathway include the SHH ligand and the transmembrane proteins PTCH1 and SMO |
| PMC3759017__F1 | Key mutational and therapeutic targets in melanoma |
| PMC3759173__F3a | Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Signaling Pathways and Novel Genes Controlling Resistance and Malignancy |
| PMC3759173__F4a | Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Signaling Pathways and Novel Genes Controlling Resistance and Malignancy |
| PMC3759196__F6 | RTK/PI3K/Akt signaling |
| PMC3759196__F7 | P53 pathway and retinoblastoma (RB) tumor suppressor protein signaling are shown |
| PMC3759196__F9 | Aberrant Signaling Pathways in Glioma. |
| PMC3759360__F2 | When Ubiquitin Meets NFKB: A trove for anti-cancer drug development |
| PMC3759367__F11 | Signaling pathway and proposed sites of arsenite perturbation |
| PMC3759480__F3 | Wnt/Beta-catenin signaling was activated in gemcitabine resistant NSCLC cell lines |
| PMC3759481__F1 | Simplified schematic shows the major intracellular signal transduction pathways that regulate the epithelial-to-mesenchymal transition (EMT) process in fibrotic kidneys |
| PMC3759561__F1 | Regulation of Muscle Protein Synthesis and the Effects of Catabolic States |
| PMC3759646__F1 | Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia |
| PMC3759750__F2 | Regulation of prosurvival and apoptotic pathways by ER stress |
| PMC3759859__F2 | Oncogenic role of the AKT signaling pathway |
| PMC3759859__F3 | p53-induced cell cycle control and apoptosis |
| PMC3759859__F4 | Interplay between p53 and AKT/mTOR in regulating autophagy |
| PMC3759924__F2 | Lin28/let-7 regulatory axis |
| PMC3760013__F5 | Core genes for cetuximab and PX-866 susceptibility |
| PMC3760066__F2 | Two TLR signaling pathways |
| PMC3760419__F4 | Cell Death in Disease: Mechanisms and Emerging Therapeutic Concepts |
| PMC3760459__F1 | MTOR signaling pathway |
| PMC3760546__F4 | Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease. |
| PMC3760627__F2 | Diving adaptations in the Chinese alligator genome |
| PMC3760732__F8 | Pathway interactions among HGF/c-Met, PI3K/Akt, and Notch signaling pathways |
| PMC3760860__F6 | Organized Emergence of Multiple-Generations of Teeth in Snakes Is Dysregulated by Activation of Wnt/Beta-Catenin Signalling |
| PMC3760899__F3 | Comparative Transcriptome Profiling of an SV40-Transformed Human Fibroblast (MRC5CVI) and Its Untransformed Counterpart (MRC-5) in Response to UVB Irradiation |
| PMC3761196__F7 | Cell compartment view for network of lipid metabolic genes highlighting the role of SREBF1, THRSP, and ESRRA curated by ingenuity pathway analysis (IPA) |
| PMC3761196__F8 | This figure depicts a model of the lipid synthesis genes in the human mammary epithelial cell during secretory activation according to cell compartment |
| PMC3761286__F1 | Diagram showing Na-K-ATPase control of cell function by ouabain via its ion transport and signaling functions |
| PMC3761885__F2 | Proposed regulation of cardiac Per2 |
| PMC3762088__F2 | Regulation of autophagy by oncogenes and tumor suppressors |
| PMC3762125__F5 | Synergy between RasGRP and SOS in TCR signaling |
| PMC3762275__F2 | Recognition of particulate and soluble Beta-glucans by dectin-1 and signal transduction in macrophages and DCs |
| PMC3762301__F3 | Molecular inhibitory mechanism of cPAP to block proliferation and survival of prostate cells |
| PMC3762654__F11 | Network analysis of light pathway genes regulated in but not in phyA-211 upon prolonged exposure to low / |
| PMC3762672__F1 | PI3-K signaling.Notes: Activation of class I PI3-K via RTK phosphorylates and activates downstream target PDK1, in turn phosphorylating AKT kinases at the threonine site |
| PMC3762715__F5 | Transcriptome Profiling Reveals Th17-Like Immune Responses Induced in Zebrafish Bath-Vaccinated with a Live Attenuated Vibrio anguillarum |
| PMC3762983__F2 | Example of a pathway reconstruction experiment |
| PMC3763042__F1 | Working model of renoprotective pathways activated by relaxin |
| PMC3763401__F1 | Crosstalk between COX-2 and EGF signaling pathway in CRC |
| PMC3763461__F1 | Hypothetical model explaining the pathway through which mutated htt (mhtt) causes OMM permeabilization |
| PMC3763548__F8 | Role of the eIF2A/ATF4 signaling pathway in the transcriptional activation of autophagy genes |
| PMC3763651__F1 | Schematic presentation depicting the regulation of receptor signaling through G-proteins |
| PMC3763710__F1 | The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise |
| PMC3763924__F1 | Pathways of ICL repair |
| PMC3764071__F1 | One-carbon metabolism and glutathione (GSH) synthesis and metabolism |
| PMC3764474__F1 | SIRT1-dependent deacetylation of substrate proteins |
| PMC3764486__F2 | Expanding roles for CD4+ T cells in immunity to viruses |
| PMC3764601__F4 | The meiotic recombination pathway in C |
| PMC3764819__F4 | Enrichment of the Notch signaling pathway in glioma CSCs |
| PMC3764828__F5 | Model depicting mitochondrial generation of H2O2 as a key modulator of TCR-mediated signal transduction |
| PMC3765067__F2 | Map of molecular interactions involving GADD45 proteins and cell signaling pathways generated using Ingenuity Pathway Analysis software (IPA) |
| PMC3765220__F4 | Pathway Studio analysis of the differentially expressed proteins of extremely severe HFMD serum samples. Proteins identified in Table were imported into PathwayAssist and an interaction map was created |
| PMC3765338__F3 | Altered CREB/E2F1 signalling networks in co-treated HMCs |
| PMC3765447__F3 | Signaling pathways involving EPCAM, proposed by Maetzel D et al |
| PMC3765909__F2 | Mechanism of blockade of the Wnt signalling pathway by osteocytes |
| PMC3765962__F2 | Important molecular pathways and drug targets in RCC |
| PMC3766375__F2 | Fat side of Prostate Cancer |
| PMC3766375__F3 | Fat side of Prostate Cancer |
| PMC3766629__F6 | Immunohistochemical Staining, Laser Capture Microdissection and FASP Assisted Proteomic Analysis of Target Cell Populations within Tissue Samples |
| PMC3766771__F1 | Transcriptional regulation of effector and memory CD8+ T cell fates |
| PMC3766771__F2 | Transcriptional regulation of effector and memory CD8+ T cell fates |
| PMC3766957__F2 | Cancer metabolism: fatty acid oxidation in the limelight |
| PMC3767399__F4 | The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp. |
| PMC3767435__F2 | Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia |
| PMC3767467__F4 | Proposed model of TRP47 effector function in E |
| PMC3767923__F6 | Schematic of DNA damage response to double strand breaks |
| PMC3768199__F1 | Schematic overview of hippocampal signaling pathways following sleep deprivation |
| PMC3769161__F7 | Interleukin-17 Enhancement of the Interleukin-6 Signaling Cascade in Astrocytes |
| PMC3769322__F3 | Regulation of action cytoskeleton in LTLT-Ca MCF-7 cells |
| PMC3769628__F1 | Simplified model for NHEJ and HR |
| PMC3769628__F2 | Four current models of PARP inhibitor-induced cancer cell killing |
| PMC3769666__F1 | Extrinsic and intrinsic apoptotic pathways |
| PMC3769702__F5 | Pathway diagram of the CTLA4 signaling in cytotoxic T lymphocytes from the IPA |
| PMC3770140__F2 | PHLPP suppresses the PI3K/Akt signalling pathway |
| PMC3770247__F1 | Hedgehog signaling pathway, a morphogenic signaling pathway important in embryogenesis, tissue differentiation, cell growth and development |
| PMC3770300__F1 | Computational framework of 3D vascularized bone regeneration within a porous biodegradable CaP scaffold |
| PMC3770492__F2 | A new Vitreoscilla filiformis extract grown on spa water-enriched medium activates endogenous cutaneous antioxidant and antimicrobial defenses through a potential Toll-like receptor 2/protein kinase C, zeta transduction pathway. |
| PMC3770583__F7 | Rac1/Cdc42 GTPase-Specific Small Molecule Inhibitor Suppresses Growth of Primary Human Prostate Cancer Xenografts and Prolongs Survival in Mice |
| PMC3770684__F3 | SNP (-617C>A) in ARE-Like Loci of the NRF2 Gene: A New Biomarker for Prognosis of Lung Adenocarcinoma in Japanese Non-Smoking Women |
| PMC3770777__F5 | Schematic description of the metabolic network proposed to link DFMO-mediated inhibition of polyamine synthesis to observed perturbations in the methionine cycle, trans-sulfuration pathway, purine synthesis/salvage and de novo thymidine production |
| PMC3771080__F1 | Pathway analysis depicting cytokine and cytokine receptor interactions relative to position in the cellular environment |
| PMC3772092__F7 | Cadherin 6 Is a New RUNX2 Target in TGFB Signalling Pathway |
| PMC3772101__F1 | Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway |
| PMC3772104__F1 | The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis |
| PMC3772104__F2 | Involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis |
| PMC3772106__F1 | How are STAT1 and cholesterol metabolism associated in antiviral responses? |
| PMC3772111__F4 | Computational models of the JAK1/2-STAT1 signaling |
| PMC3772119__F1 | Drosophila JAK-STAT pathway in blood cell formation and immunity |
| PMC3772385__F8 | Model describing the relationship of osteoblast-produced Bmp2 and connections to VegfA production and increased microvascularization that serves as a major niche for mesenchymal stem cells |
| PMC3772387__F8 | Recruitment of FLNa, IQGAP1 and RacGAP1 to active B1 integrin regulates Rac1 activity |
| PMC3773046__F1 | Reducing Sphingolipid Synthesis Orchestrates Global Changes to Extend Yeast Lifespan |
| PMC3773342__F5 | Genes expressed higher in mutant mice revealed networks of interacting genes |
| PMC3773342__F9 | Proposed signaling process for GDNF-independent UB outgrowth |
| PMC3773501__F1 | NOD2, an Intracellular Innate Immune Sensor Involved in Host Defense and Crohn's Disease |
| PMC3773516__F6 | MEF2C Haploinsufficiency features consistent hyperkinesis, variable epilepsy, and has a role in dorsal and ventral neuronal developmental pathways. |
| PMC3773757__F6 | Summary of the convergence of the E2-ERK and mTORC1 signaling pathways in regulating migration and invasion in LAM patient-derived cells |
| PMC3773820__F8 | Role of Nor-1 in incretin-induced insulin expression and secretion and hypothetical localization of the TCF7L2 and NR4A3 SNP effects |
| PMC3773983__F2 | Four major signaling pathways in the postsynaptic region of a neuron that combine to form a local signaling network |
| PMC3773992__F2 | Crosstalk between hedgehog signaling, Wnt/Beta-catenin signaling, notch signaling, and phosphoinositide 3 (PI3)-kinase/Akt pathway and targeting by norcantharidin (NCTD) |
| PMC3774073__F1 | Phosphorylation events and the modulation of aquaporin 2 cell surface expression. |
| PMC3774122__F2 | NRF2-mediated oxidative stress response pathway |
| PMC3774138__F1 | Role of mTOR Inhibition in Preventing Resistance and Restoring Sensitivity to Hormone-Targeted and HER2-Targeted Therapies in Breast Cancer |
| PMC3774138__F2 | Role of mTOR Inhibition in Preventing Resistance and Restoring Sensitivity to Hormone-Targeted and HER2-Targeted Therapies in Breast Cancer |
| PMC3774329__F6 | The interactions between Rho/Rho-kinase signaling and bone morphogenetic protein (BMP)/transforming growth factor (TGF)B signaling |
| PMC3774688__F1 | Helicopter Perspective on TB Biomarkers: Pathway and Process Based Analysis of Gene Expression Data Provides New Insight into TB Pathogenesis |
| PMC3774704__F1 | Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic islets |
| PMC3774790__F8 | Lmx1a Encodes a Rostral Set of Mesodiencephalic Dopaminergic Neurons Marked by the Wnt/B-Catenin Signaling Activator R-spondin 2 |
| PMC3774987__F3 | Essential TLR-associated signaling pathways and cytokine production |
| PMC3774995__F2 | Schematic representation of p30 functions |
| PMC3775123__F1 | Signaling modules responsible for autophagy-lysosome pathway in the adult |
| PMC3775123__F2 | Signaling modules that are important therapeutic targets to counteract muscle wasting |
| PMC3775241__F3 | Regulation of hepatic hepcidin induction at the cellular level |
| PMC3775269__F6 | CTLA4Ig inhibits effector T cells through regulatory T cells and TGFB. |
| PMC3775402__F2 | Alternative splicing regulation of the PI3K-mTOR pathway |
| PMC3775430__F1 | PI3K/PTEN/Akt pathway |
| PMC3775430__F5 | Model for possible sequence of genomic events in PCA progression |
| PMC3775564__F5 | Molecular network analysis of the miR-200 family and potential molecular targets with Ingenuity pathway analysis (IPA) |
| PMC3775578__F1 | Novel investigational drugs for basal cell carcinoma |
| PMC3775637__F3 | Targeting the PI3K and BTK pathways in NHL |
| PMC3775648__F1 | Major elements of the canonical Wnt signaling pathway |
| PMC3775648__F2 | Major elements of the noncanonical PCP Wnt signaling pathway |
| PMC3775648__F3 | Major elements of the noncanonical Wnt/Ca2+signaling pathway |
| PMC3775856__F10 | Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation |
| PMC3775863__F3 | MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention |
| PMC3775871__F1 | Epigenetic Regulation of SOX9 by the NFKB Signaling Pathway in Pancreatic Cancer Stem Cells |
| PMC3776022__F1 | GABAA receptor subunit regulation after status epilepticus (SE) |
| PMC3776053__F7 | A model for mid-day contrast sensitivity regulation |
| PMC3776465__F2 | Functions of the proteins encoded by the genes mutated in primary lymphedema cluster around a central molecular pathway: the VEGFR3 signaling |
| PMC3776718__F3 | Overlay of the insulin-like growth factor-1 (IGF-1) signaling pathway with microarray data for comparison of very small embryonic-like stem cells (VSELs) with hematopoietic stem cells (HSCs) |
| PMC3777178__F3 | Multifunctional phosphorylated PDZ proteins integrate signaling pathways to control hyperplasia, neoplasia, and cell metastasis |
| PMC3777336__F4 | Differentially expressed genes (DEGs) related to the cell cycle |
| PMC3777479__F2 | Niclosamide targets the Wnt/Beta-catenin, Notch, and mTORC1 pathways |
| PMC3777492__F1 | IGFBP5 enters cells through its own surface receptor or by freely diffusing into the cytoplasm |
| PMC3777916__F2 | Using Biological Pathway Data with Paxtools |
| PMC3777916__F3 | Using Biological Pathway Data with Paxtools |
| PMC3778193__F6 | Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of ERK1/2 and NFKB activation |
| PMC3778395__F1 | Plant tetrapyrrole biosynthetic pathway |
| PMC3778443__F3 | Oleoylethanolamide (OEA) signaling as a biosensor for dietary fat |
| PMC3778921__F4 | Integrative Analysis Reveals an Outcome-associated and Targetable Pattern of p53 and Cell Cycle Deregulation in Diffuse Large B-cell Lymphoma |
| PMC3779140__F2 | DNA damage signaling at replication forks |
| PMC3779140__F3 | DNA damage tolerance pathway (DDT): lesions (yellow Square) in the DNA template blocks progression of high-fidelity replicative polymerase resulting in stalled replication forks |
| PMC3779140__F4 | Proposed model for TLS pathway |
| PMC3779140__F5 | TLS synthesis in ICL repair by Fanconi anemia (FA) pathway: replicative DNA polymerase stalls upon encounter of an interstrand crosslink (ICL) in DNA |
| PMC3779382__F2 | EBV-mediated oncogenic signaling pathway activation in EBV-positive diffuse large B-cell lymphoma of the elderly |
| PMC3779382__F6 | Therapeutic modulation of EBV infection and associated signaling pathways |
| PMC3779404__F2 | Therapeutically targeting the AMP-activated protein kinase (AMPK) and mammalian target of rapamycin complex (mTORC1) signaling pathways in liver kinase B1 (LKB1) -/- tumors |
| PMC3779571__F1 | Chondrocyte gene network of CSGalNAcT-1 was classified as glycan biosynthesis and metabolism and functional pathway |
| PMC3779868__F1 | Phosphoinositide signaling and its regulation by phosphatases |
| PMC3780472__F2 | Biochemical changes during EMT in fibrosis |
| PMC3780793__F1 | Genes identified in the phosphatidylinositol and hedgehog signaling pathways |
| PMC3781192__F1 | Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults |
| PMC3781481__F2 | Classic and alternative lipogenic pathways of fructose |
| PMC3782064__F2 | Ingenuity pathway analysis |
| PMC3782205__F2 | Nephrin-adaptors complex |
| PMC3782218__F1 | Role of the proteins and mediators involved in iron homeostasis and impact of hereditary hemochromatosis protein mutations in chronic kidney disease |
| PMC3782237__F4 | Mammalian target of rapamycin pathway is deregulated by mutations in cancer |
| PMC3782367__F1 | Unfolded protein response (UPR) is activated in the autosomal dominant retinitis pigmentosa (adRP) retina and proposed to be a target for modulating the rate of retinal degeneration |
| PMC3782519__F1 | MicroRNAs as novel immunotherapeutics |
| PMC3782523__F1 | Blocking the B7-H4 pathway with novel recombinant antibodies enhances T cell-mediated antitumor responses |
| PMC3782845__F4 | Possible origin of WM precursors from IgM+ memory cells |
| PMC3782845__F5 | MYD88–an intriguing link between WM and natural effector IgM+ memory cells |
| PMC3783160__F4 | Model of the interactions of Rrp1 and Rrp2 with the mediators of two branches of HR DNA repair pathway and helicases Rqh1 and Srs2 |
| PMC3783495__F7 | Antagonism of Betulinic Acid on LPS-Mediated Inhibition of ABCA1 and Cholesterol Efflux through Inhibiting Nuclear Factor-kappaB Signaling Pathway and miR-33 Expression |
| PMC3783562__F3 | Metabolic actions of Rho-kinase in periphery and brain |
| PMC3783819__F2 | Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction |
| PMC3783819__F3 | Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction |
| PMC3783933__F1 | IIS/TOR signaling pathway in fat body and the central nervous system of Drosophila |
| PMC3784161__F1 | AKT-mammalian target of rapapmycin (mTOR) signalling pathway |
| PMC3784161__F2 | AKT controls T-cell differentiation |
| PMC3784162__F2 | Toll-like receptor 3 (TLR3) participates in both defence and offence in host immunity to viruses |
| PMC3784205__F6 | Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans |
| PMC3784243__F1 | Role of the PD-1 Pathway in the Immune Response |
| PMC3784453__F10 | Leu452His Mutation in Lipoprotein Lipase Gene Transfer Associated with Hypertriglyceridemia in Mice in vivo |
| PMC3784533__F1 | Emerging concepts in immunity to hepatitis C virus infection |
| PMC3784667__F2 | Intracellular cycling of MUC1MUC1 is phosphorylated by EGFR and other receptor tyrosine kinases |
| PMC3784815__F3 | Kidney immune activation against ischemia-reperfusion and transplant injury |
| PMC3785008__F1 | Role of hypoxia and HIF2A in development of the sympathoadrenal cell lineage and chromaffin cell tumours with distinct catecholamine phenotypic features |
| PMC3785049__F3 | Type I interferon induction is inhibited by paramyxovirus interferon-antagonist proteins at multiple stages |
| PMC3785124__F7 | Simplified network controlling the fate decisions between osteogenic and adipogenic lineages in huAFMSCs |
| PMC3785471__F2 | Host Response to Respiratory Bacterial Pathogens as Identified by Integrated Analysis of Human Gene Expression Data |
| PMC3785791__F1 | Abbreviated pathway to illustrate cGMP production and its role in oocyte meiotic arrest |
| PMC3786223__F2 | The potential role of miRNAs in the attenuated myogenic process in the elderly |
| PMC3786361__F1 | Epidermal growth factor receptor family and targeted agents |
| PMC3786574__F2 | Molecular mechanisms of T cell co-stimulation and co-inhibition |
| PMC3786590__F1 | Simple molecular pathway for sex determination in the mammalian gonads |
| PMC3786590__F3 | Neuroendocrine control of pituitary and gonadal function |
| PMC3787041__F5 | Live Attenuated Rev-Independent Nef¯SIV Enhances Acquisition of Heterologous SIVsmE660 in Acutely Vaccinated Rhesus Macaques |
| PMC3787240__F2 | Selected non-epigenetic effects of sulforaphane and I3C/DIM on prostate cancer cells |
| PMC3787301__F4 | The physiological and metabolic landscape of Melainabacteria |
| PMC3787304__F1 | Different phosphorylation sites on STAT3 mediate canonical and non-canonical functions of the Notch signaling pathway |
| PMC3787380__F2 | Intracellular signaling pathways activated by guidance cues |
| PMC3787652__F2 | Differentiation and commitment of IL-17-producing T helper (TH)17 cells in the midpoint of other coacting cells in favor of and against the harboring individual |
| PMC3787764__F8 | Proposed molecular pathway governing multiciliogenesis |
| PMC3787923__F2 | The role of chemotherapy and latest emerging target therapies in anaplastic thyroid cancer. |
| PMC3787928__F2 | Action of Smac mimetics.Notes: IAPs are important regulators of NFKB-activating signaling pathways |
| PMC3788099__F7 | Association between Inflammatory Infiltrates and Isolated Monosomy 22/del(22q) in Meningiomas |
| PMC3788325__F2 | Signaling pathways in RILF |
| PMC3788328__F1 | Calcium and calcium-permeable channels in the control of autophagy |
| PMC3788359__F3 | Pathways linking hypoxia to CSCs and EMT in tumor aggressiveness |
| PMC3788606__F3 | TGFB signaling |
| PMC3789182__F7 | Schematic illustrating a model of NA anticancer activity is proposed |
| PMC3789189__F8 | CVB3-induced the PI3K-Akt-mTOR-apoptosis signaling pathway |
| PMC3789231__F7 | Mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3) |
| PMC3789261__F3 | Pathways impinging specifically on glucose-mediated F-actin remodeling in the B cell |
| PMC3789264__F5 | Ingenuity Pathway Analysis (IPA)-generated network of isobaric tag for relative and absolute quantitation (iTRAQ)-identified proteins and their interacting partners in Alzheimer's disease (AD) hippocampus (Hp) |
| PMC3789264__F6 | Ingenuity Pathway Analysis (IPA)-generated network of isobaric tag for relative and absolute quantitation (iTRAQ)-identified proteins and their interacting partners in Alzheimer's disease (AD) parietal cortex (pCx) |
| PMC3789264__F7 | Ingenuity Pathway Analysis (IPA)-generated network of isobaric tag for relative and absolute quantitation (iTRAQ)-identified proteins and their interacting partners in Alzheimer's disease (AD) cerebellum (Cb) |
| PMC3789264__F8 | Brain site-specific proteome changes in aging-related dementia. |
| PMC3789714__F1 | Feeding Uninvited Guests: mTOR and AMPK Set the Table for Intracellular Pathogens |
| PMC3789782__F1 | Herpes Simplex Virus Type 1 Single Strand DNA Binding Protein and Helicase/Primase Complex Disable Cellular ATR Signaling |
| PMC3790457__GA1 | Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway |
| PMC3790664__F1 | Comparing feedback mechanisms in morphogen signaling |
| PMC3791171__F1 | Molecular pathogenesis and mechanisms of thyroid cancer |
| PMC3791171__F2 | Molecular pathogenesis and mechanisms of thyroid cancer |
| PMC3791171__F4 | Molecular pathogenesis and mechanisms of thyroid cancer |
| PMC3791178__F1 | The Autophagy Pathway by Human Tumor Viruses |
| PMC3791603__F1 | Hh signaling in animals |
| PMC3791614__F1 | The interactions between the control of the cell cycle and the expression of specific ligands for activating NK receptors in various pathologies |
| PMC3792024__F4 | Meta-Analysis Identifies NFKB as a Therapeutic Target in Renal Cancer |
| PMC3792350__F1 | Overview of peroxisome biogenesis: converging de novo and growth and division models |
| PMC3792371__F1 | TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma |
| PMC3792429__F1 | Hierarchy of nucleolar stress-induced neuroprotection |
| PMC3792444__F1 | Induction of migratory heterogeneity during priming |
| PMC3792586__F1 | TNF signalling pathway |
| PMC3792734__F1 | Main biosynthetic pathway of saturated and monounsaturated fatty acids |
| PMC3792737__F9 | Summary of the interactions identified in this work between Dmrt5 and the secreted ligands and Wnt/Bmp regulated graded transcription factors expressed during early patterning of the cerebral cortex |
| PMC3793031__F2 | Symbiotic signaling downstream of oscillations |
| PMC3793056__F5 | Predictive metabolic pathway of biosynthesis in M |
| PMC3794211__F2 | MiRNAs implicated in neurodegeneration |
| PMC3794382__F1 | Gene sets are not pathways |
| PMC3794556__F3 | Signaling pathways involved in EndoMT |
| PMC3794709__F1 | Steps in the reverse cholesterol transport pathway |
| PMC3794713__F1 | Simplified overview of commonly mutated oncogenes, tumor suppressors, and pathways in endocrine cancer |
| PMC3794713__F2 | mTOR and MAPK pathways |
| PMC3795238__F8 | A model depicting androgen-AR-miR-29a regulation loop |
| PMC3795344__F3 | Schematic diagram illustrating a proposal for the involvement of Cdx2 during progression of cancers through the serrated pathway |
| PMC3795364__F6 | Schematic presentation of the influence of angiogenesis inhibitors on EC signaling |
| PMC3795378__F2 | Tumor (SVZ) micro-environment |
| PMC3795998__F1 | Signaling pathways of the UPR in response to ER-stress |
| PMC3796213__F2 | Connectivity map of NRF2-mediated oxidative stress response adapted from IPA software |
| PMC3796519__F6 | IL-27 Enhances the Expression of TRAIL and TLR3 in Human Melanomas and Inhibits Their Tumor Growth in Cooperation with a TLR3 Agonist Poly(I:C) Partly in a TRAIL-Dependent Manner |
| PMC3797025__F7 | Schematic model of adaptive primary resistant responses by tumors to anti-IGF-1R monoclonal antibodies (mAbs) |
| PMC3797167__F7 | Illustration of the proposed mechanisms underlying the crosstalk between insulin/IGF1 and IL-17 signaling pathways |
| PMC3797199__F1 | Aryl Hydrocarbon Receptor Promotes RORGt+ ILCs and Controls Intestinal Immunity and Inflammation |
| PMC3797434__F7 | IL-32-PAR2 axis is an innate immunity sensor providing alternative signaling for LPS-TRIF axis |
| PMC3797455__F10 | Nrx in Wnt/Dvl and Toll-like receptor 4 (TLR4) signaling |
| PMC3797650__F1 | Diagram of hedgehog (Hh) signaling in mammalian cells |
| PMC3797768__F4 | An Integrated Approach Based on Multiplexed Protein Array and iTRAQ Labeling for In-Depth Identification of Pathways Associated to IVF Outcome |
| PMC3797786__F3 | Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells |
| PMC3797807__F4 | Cell Survival Following Radiation Exposure Requires miR-525-3p Mediated Suppression of ARRB1 and TXN1 |
| PMC3798018__F1 | PLD and phosphatidic acid in the cell |
| PMC3798191__F5 | The relationships between the RA, FGF and Notch pathway in Xenopus PSM |
| PMC3798256__F1 | Pathways involved in stem cell hemostasis via regulation of nutrient sensing |
| PMC3798270__F6 | The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally |
| PMC3798724__F3 | Hedgehog signaling pathway in the primary cilia |
| PMC3798767__F5 | p53 regulated developmental pathways |
| PMC3798821__F4 | The valine degradation pathway from the differentially regulated genes in response to 3-7 days of mechanical overload |
| PMC3798821__F6 | The ILK signaling and its putative regulation by the micro-RNA-1 (miR-1) |
| PMC3798916__F1 | Methylation cycle |
| PMC3798933__F2 | Insulin signaling pathways are inhibited by damage-associated molecular pattern (DAMP)-mediated, Toll-like receptor (TLR)-mediated pathways |
| PMC3798952__F1 | EpCAM and WNT signalling pathways |
| PMC3799205__F1 | The leptin-induced pathways |
| PMC3799862__F5 | Role of TRAF6 in RANK Signal Transduction Pathway |
| PMC3799998__F1 | Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila |
| PMC3800035__F7 | Heterotrimeric G-Protein, GA16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer |
| PMC3800061__F2 | Basic NOD2/RIP2 pathway of NFKB activation |
| PMC3800064__F2 | The canonical and noncanonical NFKB pathway |
| PMC3800433__F1 | The central role of group 2 innate lymphoid cells (ILC2s) in type 2 immunity |
| PMC3801100__F1 | RSK isoforms control motility and other aspects of tumor cell invasion and metastasis |
| PMC3801191__F1 | Estrogen Regulation of Dkk1 and Wnt/Beta-Catenin Signaling in Neurodegenerative Disease |
| PMC3804031__F3 | Targeting the RAS oncogene. |
| PMC3804348__F1 | Regulation of lipid metabolism in glioblastoma and the therapeutic drug targets |
| PMC3804751__F7 | Model showing the cRAF-dependent modulation of DC responses by TcES |
| PMC3805541__F3 | MicroRNA Profiling in Prostate Cancer - The Diagnostic Potential of Urinary miR-205 and miR-214 |
| PMC3805607__F2 | Comparative Transcriptional Profiling of 3 Murine Models of SLE Nephritis Reveals Both Unique and Shared Regulatory Networks |
| PMC3805607__F3 | Comparative Transcriptional Profiling of 3 Murine Models of SLE Nephritis Reveals Both Unique and Shared Regulatory Networks |
| PMC3805859__F1 | Integration of microRNA and epigenetic regulation pathways |
| PMC3805993__F2 | Novel KP/KISS1R signaling pathways in breast cancer cells lacking the estrogen receptor, ERA |
| PMC3806061__F1 | Diagrammatic representation of the hedgehog (Hh) signaling pathway |
| PMC3806315__F2 | Serine, glycine and the one-carbon cycle: cancer metabolism in full circle |
| PMC3806315__F4 | Serine, glycine and the one-carbon cycle: cancer metabolism in full circle |
| PMC3806458__F1 | Scheme of the biochemical pathways leading to carotenoids and other terpenoids |
| PMC3806867__F5 | High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells |
| PMC3807000__F2 | Autophagy-related common pathway in neurodevelopmental disorders |
| PMC3807052__F1 | Migration of opioid-containing immune cells and opioid release within inflamed tissue |
| PMC3807240__F1 | The NLRP3 inflammasome regulates the DNA damage response pathway |
| PMC3807489__F8 | Proposed metabolic models for syntrophic growth of D |
| PMC3807757__F1 | MyD-88 dependent TLR signaling pathway: MyD-88 (*) associates with the cytoplasmic domain of TLR, recruiting IRAK1 and IRAK4 to activate TRAF6 |
| PMC3807853__F9 | IL-33 markedly activates murine eosinophils by an NFKB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop |
| PMC3808116__F2 | Schematic overview of multiple feedback loops in the PI3K pathway |
| PMC3808153__F7 | The 5S RNP Regulates p53 Homeostasis and Its Activation in Response to Nucleolar and p14ARF OverexpressionSchematic overview showing the central role of the 5S RNP in coupling the pathway of ribosome biogenesis to cellular proliferation |
| PMC3808218__F1 | PI3K/Akt/mTOR pathway |
| PMC3808235__F1 | Pathway-guided treatment in prostate cancer |
| PMC3808414__F8 | Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy |
| PMC3808429__F6 | Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology |
| PMC3808429__F7 | Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology |
| PMC3808753__F1 | Coordinated action of glial and neuronal purinergic receptors and purines in the CNS |
| PMC3808934__F1 | RLR-mediated pathways of type I interferon and inflammatory responses |
| PMC3808934__F2 | Interplay of TLR and RLR signaling |
| PMC3809064__F1 | Targeting Mutant Fibroblast Growth Factor Receptors in Cancer. |
| PMC3809361__F1 | Metabolism of cancer cells is regulated by signaling pathways related to oncogenes and tumor-suppressor genes |
| PMC3809539__F5 | Gene Regulatory Network for cenH3 Deposition in Arabidopsis and Coexpression of KNL2 and cenH3 with Genes of the RBR-E2F Transcription Regulation Pathway and with DNA and H3 Methyltransferases.(A) Key regulator genes are indicated by yellow octagons |
| PMC3809585__F2 | TAM receptor signaling pathways |
| PMC3809585__F3 | TAM-regulated cycle of inflammation in dendritic cells |
| PMC3809754__F1 | Biogenesis and function of microRNAs |
| PMC3809843__F9 | Gremlin regulation of LOXs in TM |
| PMC3810143__F9 | Downregulation of Nuclear-Encoded Genes of Oxidative Metabolism in Dialyzed Chronic Kidney Disease Patients |
| PMC3810296__F2 | NLRP6 in Infection and Inflammation |
| PMC3810304__F1 | Potential pathways by which CKD modulates the accumulation of arterial macrophages |
| PMC3810594__F1 | Renin-angiotensin-aldosterone system and regulation of insulin signaling phosphorylation of docking protein insulin receptor substrate -1 (IRS-1) is the major converging point in insulin signaling |
| PMC3810612__F6 | Schematic diagrams of midsagittal sections through (A) the rainbow trout and (B) rat brains to summarize the contributions and interactions of the serotonergic and corticotropin-releasing factor (CRF) systems in the regulation of food intake |
| PMC3810677__F1 | Regulation of the HIF pathway by oxygen dependant and independent mechanisms (a) Under normoxia, prolyl hydroxylase domain proteins use oxygen and Alpha-ketoglutarate as substrates to hydroxylate conserved proline residues on HIFA subunits |
| PMC3811010__F3 | Target genes of CDX1 and CDX2, and the BMP/TGFB signaling pathway |
| PMC3811055__F2 | mTOR pathway |
| PMC3811159__F2 | Feedback signaling following mTORC1 inhibition |
| PMC3811932__F1 | Growth factors, insulin, nutrients and energy status regulate the activation of the PI3K/Akt/mTOR signaling network |
| PMC3812160__F7 | Transcriptome-Wide Mapping of Pea Seed Ageing Reveals a Pivotal Role for Genes Related to Oxidative Stress and Programmed Cell Death |
| PMC3812255__F2 | Serotonin Gene Variants are Unlikely to Play a Significant Role in the Pathogenesis of the Sudden Infant Death Syndrome |
| PMC3812405__F9 | Proposed Model for EtOH and PA regulation of mTORC1 and mTORC2 signaling |
| PMC3812667__F1 | Bcl-2 inhibition may act directly on tumor cells but may also target the nutrient supply to the tumor by disrupting the blood vessels that form around, and within, the tumor () |
| PMC3812807__F7 | PKCE ACTIVATION PROMOTES FGF-2 EXOCYTOSIS AND INDUCES ENDOTHELIAL CELL PROLIFERATION AND SPROUTING |
| PMC3812980__F6 | Proposed schema of how the BMP signaling axis limits neurogenic muscle wasting |
| PMC3813433__F1 | Dietary flavonoid fisetin: A novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management |
| PMC3813872__F7 | Models of Eph signaling in amphid axon guidance |
| PMC3814227__F2 | Autophagy: regulation |
| PMC3814228__F1 | Schematic diagram of the adiponectin-AMPK pathway in glomerular cells |
| PMC3814314__F5 | Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish |
| PMC3814314__F6 | Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish |
| PMC3814363__F4 | Structure-based phylogenetic tree of ATPase enzymes |
| PMC3814391__F7 | DNA end resection |
| PMC3814597__F2 | General activation of interferonB (IFNB) transcription and induction of IFN-stimulated genes |
| PMC3814599__F1 | The nuclear pore complex (NPC) and classical nuclear import pathway |
| PMC3814639__F2 | Schematic model of the Nrf2-Keap1 signaling pathway |
| PMC3814639__F3 | Cross-talk between Nrf2 and other proteins |
| PMC3814821__F8 | Proposed mechanism for the CD8+-cell-mediated suppression of HIV-1 replication |
| PMC3814888__F5 | Mitochondrial activity pathway |
| PMC3815023__F2 | Functional Networking of Human Divergently Paired Genes (DPGs) |
| PMC3815439__F13 | MicroRNAs: molecular features and role in cancer |
| PMC3815562__F1 | Outline of steps mediating androgen synthesis and metabolism in prostate cancer cells |
| PMC3815682__F1 | Comparison of typical mammalian cell citrate metabolism and the metabolic pathway for net citrate production |
| PMC3815777__F2 | Putative intracellular cascades activated by cyclic di-nucleotides |
| PMC3815941__F3 | Bacterial and host effector molecules with potential probiotic effects |
| PMC3816228__F2 | Receptors involved in allergen recognition and uptake by AECs |
| PMC3816537__F3 | Pathway based analysis of high ranking composite score genes reveals key signaling pathways associated with PDAC clinical progression |
| PMC3816662__F1 | PI3K/Akt/mTOR signaling pathway |
| PMC3816993__F2 | Combined miRNAs and transcription factor regulation of inflammation in wound healing |
| PMC3817019__F1 | How the VEGF-A signaling pathway is linked to its main biological functions.Notes: VEGF-A can bind VEGFR-2 dimer |
| PMC3817019__F2 | EGFR pathway and its main downstream effectors, PI3K/AKT and KRAS/BRAF/MEK/MERK.Notes: Activated AKT and MEK/MERK can induce cancer cell proliferation and invasion |
| PMC3817541__F1 | Mechanism of activity-dependent transcriptional repression by MeCP2 |
| PMC3817619__F7 | Infarction Induced Myocardial Apoptosis and ARC Activation |
| PMC3817717__F2 | Ingenuity Pathway Analysis (Ingenuity Systems, Inc., Redwood City, CA) of endothelial gene expression |
| PMC3817731__F3 | Activation of the EGFR pathway and the consequent engagement of the Ras/Raf/MAPK and PI3K/Akt pathways |
| PMC3817742__F7 | ABCB10 and heme synthesis pathway |
| PMC3818123__F9 | IL-22 activates oxidant signaling in pulmonary vascular smooth muscle cells |
| PMC3818842__F6 | Major apoptotic pathways in SGNs induced by oubain treatment |
| PMC3818951__F1 | steoclastogenesi |
| PMC3819010__F2 | EBPR metabolic map inferred from the Accumulibacter clade IIA genome, adapted from ) |
| PMC3819050__F2 | Wnt7a signals bi-directionally at vertebrate synapses |
| PMC3819341__F1 | Summary of therapeutic invention points in the myostatin signaling pathway |
| PMC3819657__F3 | Combined miRNA/mRNA regulatory and functional enrichment network |
| PMC3819728__F1 | Unfolded protein response and its regulation on cell activities |
| PMC3819741__F2 | Identification of the genes in the MAPK signaling pathway that harbor or are in the close proximity of SNPs associated with feed efficiency |
| PMC3819805__F11 | Folate biosynthetic pathway in Plasmodium falciparum |
| PMC3820238__F1 | Schematic overview of TGFB signaling |
| PMC3820259__F2 | Roles of lipids in the tumour microenvironment |
| PMC3820435__F3 | Cell death signaling by the ER stress response/UPR |
| PMC3820452__F2 | Working model for the signaling mechanisms that mediate the cellular functions of TRPM7 in pancreatic adenocarcinoma |
| PMC3820452__F4 | Working model for the proliferative, prosurvival, and migratory roles of TRPM8 in pancreatic adenocarcinoma cells |
| PMC3820512__F5 | Linking Transcriptional Changes over Time in Stimulated Dendritic Cells to Identify Gene Networks Activated during the Innate Immune Response |
| PMC3820535__F7 | Modeling Integrated Cellular Machinery Using Hybrid Petri-Boolean Networks |
| PMC3820561__F1 | BRCA1 domain structure and subcellular transport pathways |
| PMC3820656__F1 | Scheme of the endothelial angiopoietin (Angpt)/Tie2 system highlighting fundamental signalling pathways |
| PMC3820944__F6 | Representative Tyr phosphorylation sites affected by erlotinib in the EGFR and ErbB2 canonical pathways |
| PMC3820966__F1 | Cellular response to oxidative stress mediating by Beta-adrenergic response and sirtuins involvement |
| PMC3821079__F1 | Schematic representation and overview of PI3K/AKT/mTOR/PTEN signaling |
| PMC3821079__F3 | Several inhibitors linked to the PI3K/AKT/mTOR/PTEN signaling pathway are shown |
| PMC3821554__F1 | The TGFB signaling pathway is regulated at multiple points by ubiquitin-mediated targeting and proteasomal degradation |
| PMC3821580__F2 | Schematic representation of the functional/physical relationship between Dystrophin-Syntrophins-nNOS pathway and miRNAs involved in such signaling, both in a WT and a DMD context |
| PMC3821792__F2 | TLR-4 signaling pathway.Notes: TLR-4/MD-2 complex homodimerization activates the MyD88-dependent pathway and TRIF-dependent pathway |
| PMC3821857__F7 | DOK2 Inhibits EGFR-Mutated Lung Adenocarcinoma |
| PMC3821994__F1 | PI3K/AKT/mTOR signaling pathway showing interacting activation and regulatory feedback loops |
| PMC3822007__F1 | New developments in the Induction and Antiviral Effectors of Type I Interferon |
| PMC3822435__F3 | Molecular Pathogenesis of Endometrial and Ovarian Cancer |
| PMC3822531__F2 | Regulation of Wnt/-catenin signalling pathway.(A) Wnt forms a ternary complex with Fz and Lrp5/6, which promotes stabilization of Beta-catenin, thereby activating the pathway |
| PMC3822533__F3 | Unfolded protein response in mammalian cells |
| PMC3822617__F3 | Multifunctionality of ARC in regulating apoptosis signalling |
| PMC3822721__F3 | FHL1 isoform KyoT2 and Notch signaling |
| PMC3822800__F5 | Diagram represents the molecular cross-talk between TLR2 heterodimers with TLR6/TLR1 and GR through the participation of PI3K |
| PMC3822825__F2 | E2F1-induced apoptosis |
| PMC3822826__F2 | Canonical Wnt/Beta-catenin signalling pathway |
| PMC3822957__F11 | P60TRP signalling based on the results obtained from different systems including NSCs, PC12 cells and p60TRP transgenic mice |
| PMC3823093__F4 | Network analysis of proteomics using IPA |
| PMC3823111__F4 | Diagram of the glycolytic pathway |
| PMC3823115__F1 | TGFa/EGFR signal pathway may directly or indirectly lead to c-Met, while HGF/c-Met does not affect the phosphorylation of EGFR |
| PMC3823115__F3 | Potential mechanism of the HGF/ c-Met signal pathway hallmarks in lung cancer |
| PMC3823132__F1 | Potential mechanism(s) of endocrine-disrupting chemicals (EDC) action |
| PMC3823134__F2 | Schematic pathway of different steps of autophagy |
| PMC3823158__F1 | Canonical NFKB signalling pathway |
| PMC3823407__F8 | Proposed model of the effect of crocetin on cardiac hypertrophy, inflammation and fibrosis |
| PMC3823475__F2 | Membrane VEGF receptors expressed by astroglial tumour cells |
| PMC3823507__F1 | Post-translational regulation of iron homeostasis |
| PMC3823580__F8 | Synergistic Effect of Everolimus and Chloroquine on Endothelial Cell Number Reduction Is Paralleled by Increased Apoptosis and Reduced Autophagy Occurrence |
| PMC3823597__F7 | Hypoxia-Induced Changes in the Bioactivity of Cytotrophoblast-Derived Exosomes |
| PMC3823599__F7 | MiR-103 Controls Milk Fat Accumulation in Goat (Capra hircus) Mammary Gland during Lactation |
| PMC3823708__F9 | NFKB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma |
| PMC3823960__F6 | Summary of retinoid pathway |
| PMC3824005__F1 | Core components of the apoptotic machinery |
| PMC3824005__F3 | Canonical and noncanonical functions of the apoptotic machinery |
| PMC3824029__F1 | Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease |
| PMC3824052__F2 | Smoking-Induced CXCL14 Expression in the Human Airway Epithelium Links Chronic Obstructive Pulmonary Disease to Lung Cancer |
| PMC3824073__F2 | Outline of the Crosstalk between p53 Family Members and the mTORC1 Pathwayp53 and p63 act upstream of mTORC1 and inhibit mTORC1 activity via multiple transcriptional targets |
| PMC3824101__F1 | Mechanisms involved in type I IFN production and its receptor signaling |
| PMC3824408__F1 | Unveiling the last missing link of the cardiolipin synthetic pathway in mitochondria |
| PMC3824536__F1 | Druggable Drivers of Lung Cancer |
| PMC3824607__F1 | TNFAlpha-mediated transient IKK activation pathways |
| PMC3824607__F3 | Crosstalk in TNFR1 signaling |
| PMC3824660__F2 | Interrelations between autophagy-related signaling and cell growth control in response to stress |
| PMC3825115__F1 | Notch pathway effects on cytoskeletal plasticity |
| PMC3825194__F1 | TGFB signaling through Smad-dependent and Smad-independent pathways |
| PMC3825194__F4 | TGFB signaling pathway inhibitors under development for potential cancer therapy |
| PMC3825415__F3 | FGFR signaling pathway |
| PMC3825489__F3 | Cross talk between the coagulation and complement system |
| PMC3825518__F1 | From Evolution to Revolution: miRNAs as Pharmacological Targets for Modulating Cholesterol Efflux and Reverse Cholesterol Transport |
| PMC3825669__F3 | KEGG "cell cycle" pathway relevant to NRF1 target genes |
| PMC3825669__F4 | KEGG "Parkinson's disease" pathway relevant to NRF1 target genes |
| PMC3825669__F6 | IPA "regulation of eIF4 and p70S6K signaling" pathway relevant to NRF target genes |
| PMC3825725__F1 | Janus face of cyclophosphamide |
| PMC3825743__F5 | Quantitative Phosphoproteomic Profiling of Human Non-Small Cell Lung Cancer Tumors |
| PMC3826118__F1 | Role of Calcium, Vitamin D, and the Extrarenal Vitamin D Hydroxylases in carinogenesis |
| PMC3826168__F2 | Molecular mechanism and function of CD40/CD40L engagement in the immune system |
| PMC3826451__F2 | Toll-Like Receptors (TLR) signaling pathway involved in RSV and hMPV-induced gene expression |
| PMC3826451__F4 | Intracellular PRR signaling pathways involved in RSV and hMPV-induced gene expression |
| PMC3826456__F2 | Diagram of PI3K/Akt and Ras/Raf pathway (see text for details) |
| PMC3826519__F7 | Deregulated genes upon miR-196a overexpression in keratinocytes |
| PMC3826519__F8 | Deregulated genes upon miR-10b overexpression in FaDu cell line |
| PMC3827118__F1 | Wnt-dependent pathway responses |
| PMC3827118__F2 | Hh signaling in mammals |
| PMC3827157__F4 | Transcriptome Analysis of PPARG Target Genes Reveals the Involvement of Lysyl Oxidase in Human Placental Cytotrophoblast Invasion |
| PMC3827358__F8 | Lipopolysaccharide Induces Degradation of Connexin43 in Rat Astrocytes via the Ubiquitin-Proteasome Proteolytic Pathway |
| PMC3827506__F5 | Signaling by innate immune receptors |
| PMC3827622__F5 | Proposed genetic networks of osseointegration |
| PMC3827695__F4 | Women and Lung Cancer: What's New? |
| PMC3827721__F4 | In silico method for modelling metabolism and gene product expression at genome scale |
| PMC3827772__F4 | Dual coordinated regulation of CYP7A1 by the FXR-SHP-LRH-1 and FXR-FGF15/19-FGFR4 pathways |
| PMC3827841__F3 | Protein-protein interaction network and SPIA analysis of the 28 up-regulated genes related to positive regulation of cell proliferation and 21 down- regulated genes related to negative control of cell proliferation |
| PMC3827841__F6 | TGFB and NOTCH activation in AoSMCs stimulated with P |
| PMC3828201__F1 | ERK and PI3K signaling networks are shown, with illustrations of feedback loops and cross talk |
| PMC3828517__F7 | A model for Norrin-mediated Fz4 receptor activation |
| PMC3828559__F1 | RAS-RAF pathway and immunohistochemical staining of colorectal cancer specimens with BRAF V600E mutation specific monoclonal antibody |
| PMC3828572__F8 | mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions |
| PMC3828604__F1 | Interactions of stress proteins and cell surface TLR signaling pathways |
| PMC3828604__F3 | Stress proteins in crosstalk with cytoplasmic PRR signaling |
| PMC3828628__F1 | IL-6 Paradox: Context Dependent Interplay of SOCS3 and AMPK |
| PMC3828651__F2 | Molecular events associated with tumor suppressor gene product-induced senescence or apoptotic cell death of tissue-resident stem/progenitor cells during chronological aging |
| PMC3828821__F1 | How does the metabolism of tumour cells differ from that of normal cells |
| PMC3829115__F1 | Schematic overview of TF signaling complexes |
| PMC3829153__F8 | Molecular mechanism of DSS-induced colitis in murine model |
| PMC3829165__F9 | Schematic illustrating the signaling pathways for TGFB1-induced down-regulation of VE-cadherin and the inhibition of cell invasion in human trophoblast cells |
| PMC3829196__F2 | The p53-mediated apoptotic signaling pathways |
| PMC3829308__F1 | Interferon beta signaling pathway |
| PMC3829478__F9 | Wnt3a binds to Fz7 and cross-activate the IGF-1-PI3k-Akt pathway inducing initial axonal outgrowth and neuronal polarization |
| PMC3829599__F1 | mTOR pathway signaling cascade |
| PMC3829661__F2 | Schematic overview ofP |
| PMC3829803__F7 | Retinoid action during paramyxovirus infection |
| PMC3829921__F1 | Small GTPases as regulators of cell division |
| PMC3830198__F5 | Model showing the proposed mechanisms of lncRNA-mediated regulation of the p53 pathway |
| PMC3830525__F4 | Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells |
| PMC3830611__F1 | Circuitry and biochemical basis for Tuberous Sclerosis symptoms: From Epilepsy to Neurocognitive deficits |
| PMC3830643__F2 | Lipid Synthesis in Protozoan Parasites: a Comparison Between Kinetoplastids and Apicomplexans |
| PMC3830939__F2 | Tudor: a versatile family of histone methylation 'readers' |
| PMC3831179__F14 | Pathway databases |
| PMC3831322__F5 | Scheme illustrating potential mechanisms by which nandrolone reduces bone loss after SCI |
| PMC3832239__F2 | Mitochondrial Retrograde Signaling at the crossroads of tumor bioenergetics, genetics and epigenetics |
| PMC3832246__F1 | TNFR1 signaling of cell survival/proinflammatory and apoptosis pathways. Upon TNF receptor activation, complexes I (survival pathway) and II (apoptosis) are formed |
| PMC3832598__F7 | CD43 Promotes Cells Transformation by Preventing Merlin-Mediated Contact Inhibition of Growth |
| PMC3832913__F3 | Alternative pathway |
| PMC3833059__F7 | Scheme of the proposed LIF signaling pathway in trophoblasts |
| PMC3833184__F3 | Lineage-specific positive selection in the naked mole rat BRCA1/FANC pathway |
| PMC3834158__F3 | Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats |
| PMC3834158__F4 | Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats |
| PMC3834200__F7 | MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells |
| PMC3834244__F1 | MiRNA biogenesis and function |
| PMC3834519__F10 | FXR/NR1H4 gene |
| PMC3834580__F2 | Future of targeted agents in metastatic colorectal cancer |
| PMC3834778__F4 | Shear stress reveals the mechanisms by which OA induces PICs and MMPs in human chondrocytes |
| PMC3834778__F5 | Networks of shear stress-induced OA progression |
| PMC3835099__F2 | Schematic drawing showing the TNF-driven survival and apoptosis balance |
| PMC3835153__F2 | Cisplatin resistance.Notes: Cisplatin creates DNA adducts and activates the apoptotic pathway, thus killing rapidly dividing cells |
| PMC3835199__F4 | = Transporter, ◊ = Enzyme, ∇ = Kinase, ∆ = Phosphatase, = Transcription regulator, 〇 = Other, = Complex/group, = Peptidase |
| PMC3835203__F1 | New mechanisms of NOD-like receptor-associated inflammasome activation |
| PMC3835370__F1 | Genomic Characterization of the Inherited Bone Marrow Failure Syndromes |
| PMC3835370__F5 | Genomic Characterization of the Inherited Bone Marrow Failure Syndromes |
| PMC3835661__F1 | Cell Death in Heart Disease |
| PMC3835685__F1 | Human epidermal growth fa ctor receptor 2 (HER2) signal transduction pathways |
| PMC3836044__F1 | Canonical (Wnt/Beta-catenin) pathway |
| PMC3836075__F5 | The role of Ang II and its metabolites in the adrenal gland vasculature |
| PMC3836169__F1 | PTEN in cancer, metabolism and aging |
| PMC3836174__F5 | Hallmarks of Aging |
| PMC3836193__F1 | Role of apoptosis in colon cancer biology, therapy, and prevention |
| PMC3836209__F1 | Metabolism of adenosine |
| PMC3836362__F6 | Interaction between dietary protein and mechanical loading on skeletal muscle cell |
| PMC3836475__F4 | Gene network associated with IFN pathway signaling |
| PMC3836673__F1 | Intracellular effects of estrogen are exerted through two main pathways, genomic and non-genomic |
| PMC3836826__F3 | Stress-response pathways are altered in the hippocampus of chronic alcoholics |
| PMC3836831__F2 | Model of PfEMP1 head structure divergence |
| PMC3837032__F7 | Impaired Nrf2 activation and antioxidant gene expression in fetal endothelial cells in GDM |
| PMC3837055__F1 | Schematic view of kallistatin action in the canonical Wnt pathway |
| PMC3837137__F6 | A diverse range of signaling pathways that can lead to persistent PKC activation to support cell migration |
| PMC3837249__F1 | Toll-like receptor signaling in liver cells |
| PMC3837323__F1 | PI3K/Akt/mTOR signaling pathway |
| PMC3837380__F7 | The Potential of 11C-acetate PET for Monitoring the Fatty Acid Synthesis Pathway in Tumors. |
| PMC3837441__F7 | The Cdc42-dependent regulation of neural differentiation in P19 cells |
| PMC3837590__F3 | Macrophage infiltration in adipose tissues, oxidative stress and IR |
| PMC3838179__F11 | Proposed model for the NOTCH-ROCK pathway and its biological significance |
| PMC3839581__F1 | Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release |
| PMC3839612__F5 | A detailed model of the Rad5-mediate template switch pathway, assuming gap filling dependent on a subset of HR functions after the replication fork has passed |
| PMC3839643__F1 | Mammalian target of rapamycin (mTOR) -centric view of nutrient sensing for the induction of forkhead box P3 (FOXP3) |
| PMC3839643__F3 | Enzymes that catabolize or use essential amino acids |
| PMC3840000__F1 | A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis |
| PMC3840213__F8 | Graphic summary of factors regulating Beta-cell proliferation and size as a function of pancreas developmental stages |
| PMC3840254__F8 | Summary of proposed pathway leading from TGFB1 receptor binding to ROS generation |
| PMC3840450__F1 | The main actors intervening in the canonical and noncanonical NFKB activation pathways |
| PMC3840450__F2 | Mechanisms of NFKB activation in T-ALL leukemic cells |
| PMC3840609__F5 | Gonadotropin-releasing hormone (GnRH) signaling pathway containing genes that are represented in the Partial Correlation Information Theory (PCIT) network "growth at the onset of puberty" |
| PMC3841024__F4 | Representative ingenuity pathway analysis (IPA) of relationship between significant genes involved in the response to mechanical stretch and/or BIRB796 treatment in engineered cardiac tissues |
| PMC3841149__F9 | WNT3 Inhibits Cerebellar Granule Neuron Progenitor Proliferation and Medulloblastoma Formation via MAPK Activation |
| PMC3841208__F4 | Contradictory KRAS mutation test results in a patient with metastatic colon cancer |
| PMC3841209__F9 | Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer |
| PMC3841210__F7 | FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancer |
| PMC3841320__F4 | Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells |
| PMC3841787__F5 | Proposed signaling pathway model for VEGF-A signaling in hypoxia-stressed BM-EPCs compiled from the proteomic and gene expression analysis is highlighted here |
| PMC3841791__F9 | Predicted upstream regulators inhibited in DA rats but activated in congenics |
| PMC3842443__F2 | Molecular Targeted Drugs and Biomarkers in NSCLC, the Evolving Role of Individualized Therapy. |
| PMC3842585__F2 | Mutations in the ERK/MAPK signaling pathway and related second messenger systems |
| PMC3843001__F9 | Proposed model of mTOR myogenic signaling |
| PMC3843069__F1 | Tryptophan metabolic pathway |
| PMC3843070__F5 | Model illustrating the potential role of CRKL in recruiting NleH1 to inhibit RPS3/NFKB signaling during A/E pathogen infection |
| PMC3843161__F3 | Biomarker-guided translation of brain imaging into disease pathway models |
| PMC3843232__F1 | Causal role for JAK2 V617F in thrombosis |
| PMC3843239__F7 | Mechanism of myosin II-mediated release of microparticles from endothelial cells activated by antiB2GPI antibodies |
| PMC3843359__F2 | MAPK signaling pathway is upregulated in OSI-906 resistant CRC lines |
| PMC3843373__F4 | The PI3K pathway is the evolutionary conserved signalling pathway to ensure that growth and development is synchronised to the appropriate metabolic conditions: energy and substrate requiring processes only proceed when a 'fed state' is indicated |
| PMC3843585__F2 | The PI3K signaling pathway |
| PMC3843886__F2 | Schematic of common signalling pathways underlying activity-dependent and leptin-dependent synaptic plasticity |
| PMC3844070__F1 | The IFNG signaling pathway |
| PMC3844273__F6 | Hypothetical estrogen signaling pathways in human cerebral vascular endothelial cells |
| PMC3844392__F1 | Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses. |
| PMC3844829__F2 | Metacoreâ„¢ apoptosis signaling pathway relating to TNF receptors, NFkB and BCL-2 antiapoptotic family genes |
| PMC3844829__F3 | Metacoreâ„¢ apoptosis signaling pathway relating to mitochondrial proteins |
| PMC3844829__F4 | Metacoreâ„¢ apoptosis signaling pathway relating to caspase activation |
| PMC3844930__F1 | Defining mitochondrial dynamics |
| PMC3844930__F5 | Mitophagy pathways |
| PMC3845018__F3 | Graft-versus-host disease signaling pathway and miRNA interactions obtained using IPA |
| PMC3845023__F1 | Sulfate assimilation pathway |
| PMC3845098__F1 | N-glycoprotein biosynthesis in mammals |
| PMC3845396__F1 | Regulation of AKT signalling activation |
| PMC3845553__F1 | IGF-1R as an anti-cancer target–trials and tribulations |
| PMC3845556__F1 | Targeting the PI3K-AKT-mTOR signaling network in cancer |
| PMC3845579__F1 | Regulation of mammalian target of rapamycin (mTOR) by the LKB1/AMPK signaling pathway |
| PMC3845601__F2 | Wnt/Beta-catenin signaling pathway |
| PMC3847144__F1 | Isoprenoid and amino acid biosynthetic pathways |
| PMC3847504__F5 | Schematic illustration of the correlation in mechanisms among detected parameters |
| PMC3847559__F5 | Combining DC vaccination with immune checkpoint blockade |
| PMC3847587__F5 | Significantly affected canonical pathway "Interferon signaling", as determined by IPAâ„¢ analysis |
| PMC3847898__F1 | Wnt signaling pathways and the effects in mature synapses |
| PMC3847901__F2 | Rat sarcoma viral oncogene homolog (RAS) activation converts normal keratinocytes to an initiated phenotype through a series of potentially reversible autocrine signals |
| PMC3847901__F3 | Divergent roles of myeloid differentiation factor 88 (MyD88) in colon carcinogenesis |
| PMC3848079__F1 | Intracellular tumour necrosis factor receptor-2 (TNFR2) signalling |
| PMC3848109__F3 | TGF-ß fibrotic pathway |
| PMC3848550__F2 | Schematic representation of the sialic acid metabolism pathway in eukaryotic cells |
| PMC3848582__F5 | Schematic model demonstrating functional involvement of NPM1, RAD50 and XRCC5 in DSB-repair in the progression of ovarian cancer cells |
| PMC3849096__F4 | Predicted flux distributions during aerobic respiratory growth with succinate |
| PMC3849481__F6 | Schematic diagram showing CSFV triggers RIG-I and MDA5 dependent signaling pathway to IRF-3 and NFKB activation to promote the production of antiviral and inflammatory cytokines in porcine alveolar macrophages |
| PMC3849489__F4 | CAND1 as a substrate receptor exchange factor |
| PMC3849582__F1 | Network Diagram of the single C |
| PMC3849657__F1 | YAP/TAZ are effectors of mechanical stress, GPCR signaling, and the Wnt signaling pathway. Mechanisms of YAP and TAZ regulation by mechanical stress, GPCR signaling, and the Wnt pathway as well as YAP/TAZ as modulators of the Wnt pathway are shown |
| PMC3849893__F1 | Interferon signaling pathway |
| PMC3849943__F2 | Network of the interactions of the miRNAs and their target genes (experimental observed or highly predicted) |
| PMC3850262__F5 | Insulin signalling pathway in hepatocytes |
| PMC3850498__F1 | Inhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells |
| PMC3851046__F7 | Proposed molecular mechanism for the inhibitory effects of zinc on RANKL-induced osteoclastogenesis |
| PMC3851544__F6 | MT1G as a tumor suppressor in thyroid cancer cells through regulating the PI3K/Akt and Rb/E2F pathways.MT1G restoration inhibited phosphorylation of Akt, leading to inhibition of cell growth |
| PMC3851681__F1 | Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection |
| PMC3851681__F2 | Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection |
| PMC3851951__F4 | Microbiota impact on the epigenetic regulation of colorectal cancer |
| PMC3851989__F2 | The second module identified by iMCMC and the corresponding known pathway in the GBM data |
| PMC3851989__F3 | The fourth module identified by iMCMC in the GBM data and locations of the detected genes in known pathways |
| PMC3851989__F4 | Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data. |
| PMC3852044__F3 | MAPK signalling pathway |
| PMC3852044__F4 | Wnt signalling pathway |
| PMC3852078__F6 | BDNF-related PPI network |
| PMC3852103__F2 | Most significant GeneGO pathway map |
| PMC3852343__F3 | Oxygen-regulated COX subunit isoform switch in yeast and mammals |
| PMC3852779__F2 | Hepatic genes differentially regulated by 17Beta-trenbolone: Impacts on metabolic pathways |
| PMC3852811__F1 | Metabolic networks of longevity |
| PMC3852967__F3 | Interaction network of genes differentially expressed in response to glatiramer acetate (GA) |
| PMC3853752__F3 | Co-expression network of 106 genes associated to the FA metabolism in P |
| PMC3853754__F1 | The mitochondrial life cycle |
| PMC3854132__F1 | Systems Modeling of Anti-apoptotic Pathways in Prostate Cancer: Psychological Stress Triggers a Synergism Pattern Switch in Drug Combination Therapy |
| PMC3854201__F4 | Biological interaction networking of PSME1 and RPS12 in chronic atrophic gastritis (CAG) |
| PMC3854349__F1 | Biochemical adaptations of mammalian hibernation and naturally induced reversible insulin resistance. |
| PMC3854412__F7 | SIRT1 negatively regulates amyloid-beta-induced inflammation via the NFKB pathway |
| PMC3854789__F1 | Dexamethasone (Dex) induces the osteogenic differentiation of stem cells by increasing the transcription of FHL-2 |
| PMC3855043__F5 | IPA pathways of ChIP-Seq-based NSRF target genes in ESC |
| PMC3855069__F1 | IL-11: a prominent pro-tumorigenic member of IL-6 family |
| PMC3855091__F6 | Foxa2 deletion leading to premature aging and age-onset obesity |
| PMC3855094__F5 | Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects |
| PMC3855094__F7 | Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects |
| PMC3855094__F13 | Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects |
| PMC3855388__F4 | CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis |
| PMC3855406__F2 | Signaling pathways of NFKB activation |
| PMC3855473__F1 | Canonical NFKB activation by TCR/CD28 and HTLV1 Tax |
| PMC3855473__F2 | Tax-specific noncanonical NFKB pathway |
| PMC3855612__F4 | Human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone |
| PMC3855668__F1 | Model of the signaling pathway mediated by ATM in response to DSBs induced by IR, as proposed by Kitagawa et al |
| PMC3855681__F4 | An Integrated Immune System Pathway in Homo sapiens and Its Interaction with Superantigen Producing Expression Regulatory Pathway in Staphylococcus aureus: Comparing Behavior of Pathogen Perturbed and Unperturbed Pathway |
| PMC3856107__F3 | Roles and signaling pathways of let-7 in hypoxia- and neural stem/progenitor cells (NSPCs)-induced angiogenesis |
| PMC3856112__F7 | Combination of pathway topology and ab initio reconstructed network |
| PMC3856238__F6 | Global Proteomics and Pathway Analysis of Pressure-overload Induced Heart Failure and Its Attenuation by Mitochondrial Targeted Peptides |
| PMC3856398__F3 | Ras-dependent versus Ras-independent extracellular signal-regulated kinase (ERK) signaling |
| PMC3856408__F1 | Endogenous small RNA pathways involved in host defense and viral pathogenesis in plants and animals |
| PMC3856443__F2 | Signal pathway implicated in disk intervertebral disk degeneration |
| PMC3856587__F3 | Simplified model of the regulatory interactions between the serotonin and stress response pathways mediated by the HPA axis |
| PMC3856862__F10 | Therapeutic Strategies to Increase Human Beta-Cell Growth and Proliferation by Regulating mTOR and GSK-3/Beta-Catenin Pathways |
| PMC3857018__F1 | Potential mechanism for active DNA methylation involving TET-mediated oxidation of 5mC, followed by TDG initiated BER pathway via recognition of 5hmC and 5fC (AP is an abasic site) (adapted from ()) |
| PMC3857020__F10 | Proposed functions of Spry1 and Spry2 in regulation of eyelid closure |
| PMC3857153__F8 | Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells |
| PMC3857155__F1 | Basic depiction of the classical view of the PI3K signaling network (black arrows) as well as the novel signaling pathway revealed in the study by Tan et al |
| PMC3857355__F3 | TGFB/Smad signal transduction pathway |
| PMC3857355__F8 | Therapeutic strategies that have been used to target the TGFB signaling pathway to reduce scarring |
| PMC3857553__F2 | Summary of Tim-3 expression on different innate immune cell populations and its functions |
| PMC3857640__F5 | Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk |
| PMC3857727__F1 | NMNATs, Evolutionarily Conserved Neuronal Maintenance Factors |
| PMC3857727__F3 | NMNATs, Evolutionarily Conserved Neuronal Maintenance Factors |
| PMC3858190__F4 | Pathways involved in sensing and responding to double-stranded RNA and other pathogen-associated molecular patterns were suppressed by SMD |
| PMC3858190__F9 | Ingenuity pathway analysis of differences between LPS and LPS + SMD (300mg/kg) with regard to reproductive hormones |
| PMC3858477__F4 | Transcriptomics of Glucocorticoid Receptor Signaling in Developing Zebrafish |
| PMC3858599__F1 | NAD+ metabolism, a therapeutic target for age-related metabolic disease |
| PMC3858858__F4 | Overall PI3K and MAPK-Erk signaling is complex, but can highly influence the balance between cell survival and death |
| PMC3859141__F1 | Molecular Pathways: Sterols and receptor signaling in cancer |
| PMC3859141__F2 | Molecular Pathways: Sterols and receptor signaling in cancer |
| PMC3859188__F4 | Pancreatic cancer initiation pathway for simulation setting (III) |
| PMC3859655__F6 | Role of miR-17 Family in the Negative Feedback Loop of Bone Morphogenetic Protein Signaling in Neuron |
| PMC3859915__F2 | Signaling downstream IL-2/IL-15RB |
| PMC3860334__F7 | Different vesicle transport pathways and the functions of Rab GTPases identified from the hUCBMSC MVs |
| PMC3860372__F1 | Metabolic Homeostasis: HDACs Take Center Stage |
| PMC3860520__F3 | Toll-like receptor (TLR)-4 signaling pathway in alcoholic liver disease |
| PMC3860870__F1 | Apoptosis by HPV early proteins: A number of the interactions of viral oncoproteins with cellular proteins and their effects on apoptosis |
| PMC3861040__F5 | Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion |
| PMC3861057__F8 | Transcriptional changes in the WNT signaling pathway of E11.5 Sost-/-; Sostdc1-/- limbs |
| PMC3861317__F3 | Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data |
| PMC3861374__F4 | Mechanism of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) |
| PMC3861642__F9 | Genes in the insulin signaling KEGG pathway that are directly or indirectly regulated by EBF1 |
| PMC3861708__F7 | Proposed models for ethylene signaling networks |
| PMC3861714__F6 | Diagrammatic representation of the BZR1-co-purified proteins identified in this study and their binding positions |
| PMC3861981__F5 | A simplified schematic diagram of the neural circuitry underlying eyeblink conditioning |
| PMC3862456__F3 | Neutral AA transporters and activation of the mTORC1 signaling pathway |
| PMC3862457__F1 | Signaling pathways that modulate amino acid, insulin/IGF-I, and resistance exercise-induced activation of mTORC1 signaling |
| PMC3862694__F10 | PTEN Increases Autophagy and Inhibits the Ubiquitin-Proteasome Pathway in Glioma Cells Independently of its Lipid Phosphatase Activity |
| PMC3863339__F1 | RACK1 signaling complexes |
| PMC3863344__F2 | Downstream targets of p38 MAPK |
| PMC3863464__F6 | Putative CA-mediated inhibitory pathway of inflammatory signaling events |
| PMC3863542__F1 | UPR signaling pathways in mammalian cells |
| PMC3863730__F6 | Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma |
| PMC3863956__F1 | Using PainNetworks to reproduce the NGF-TrkA signalling pathway |
| PMC3863956__F2 | Using PainNetworks to reproduce the NRG1-ErbB signalling pathway |
| PMC3864081__F1 | DAMP signaling through different PRRs |
| PMC3864108__F1 | Schematic diagram showing the interaction between NW arenaviruses and host innate immune response |
| PMC3864579__F1 | CD4 T-cell immunotherapy for chronic viral infections and cancer |
| PMC3864900__F3 | Ubiquitylation in immune defence and pathogen evasion |
| PMC3864900__F6 | Ubiquitylation in immune defence and pathogen evasion |
| PMC3865046__F1 | Proteasome-dependent degradation of replisome components regulates faithful DNA replication |
| PMC3865646__F2 | Apoptosis by hypothermia |
| PMC3865655__F1 | Caveolin-1 is a highly versatile regulator of cell signaling |
| PMC3865857__F1 | Conversion of ω6 and ω3 series PUFA by metabolic enzymes and interaction with de novo fatty acid synthesis |
| PMC3865857__F2 | Main enzymes and G protein-coupled receptors in the cyclooxygenase pathway |
| PMC3865866__F8 | The FBXL2- and PTPL1-dependent regulation of the PI(3)K pathway |
| PMC3865984__F1 | Autophagy Pathway |
| PMC3865984__F2 | Molecular regulation of autophagy |
| PMC3866156__F1 | Proposed mechanisms of aspirin, the single nucleotide polymorphism rs6983267, and their interaction on the WNT/CTNNB1 pathway |
| PMC3866163__F11 | Global Assessment of Antrodia cinnamomea-Induced MicroRNA Alterations in Hepatocarcinoma Cells |
| PMC3866192__F1 | Polymorphisms of CYP51A1 from Cholesterol Synthesis: Associations with Birth Weight and Maternal Lipid Levels and Impact on CYP51 Protein Structure |
| PMC3866688__F5 | Targets of immunosuppressive drugs used in solid organ transplantation, according to the 3-signal model of T-cell activation |
| PMC3866828__F3 | HVJ-E-mediated apoptosis pathway in cancer cells |
| PMC3866868__F2 | Nodal pathway activity in the determination of L-R asymmetry |
| PMC3867386__F8 | Pre-Symptomatic Activation of Antioxidant Responses and Alterations in Glucose and Pyruvate Metabolism in Niemann-Pick Type C1-Deficient Murine Brain |
| PMC3867791__F6 | Regulated in DNA Damage and Development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1) |
| PMC3867867__F3 | Genetic determination of testes in Japanese medaka fish, chicken, and mouse |
| PMC3867948__F4 | Death receptors and the extrinsic pathway of apoptosis |
| PMC3868343__F2 | Molecular basis for synergistic activation through pairs of coactivation receptors on NK cells |
| PMC3868461__F7 | Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter |
| PMC3868569__F1 | TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in Caenorhabditis elegans |
| PMC3868569__F10 | TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in Caenorhabditis elegans |
| PMC3868844__F6 | Proposed signaling network involving mTORC2 and the p38 pathway |
| PMC3868890__F2 | Main synaptic signaling mechanisms of endocannabinoid and hypocretinergic systems |
| PMC3868899__F8 | Nicotine's effect on immunity via the A4 nAChR signaling pathway in T cells |
| PMC3868999__F1 | The Hippo pathway signaling cascade results in the phosphorylation and cytoplasmic retention of effector molecules YAP and TAZ |
| PMC3870072__F2 | Diagram of BA action in targeting pathways involved in cell apoptosis and death |
| PMC3870072__F3 | Two reversing pathways between the vehicle and baicalin groups |
| PMC3870072__F4 | Subnetwork 1 and 5 of 6 networks in vehicle group |
| PMC3870072__F5 | Subnetworks 1, 2, and 4 of 9 networks in baicalin group |
| PMC3870290__F1 | Proteolytic processing of the amyloid precursor protein (APP) and Notch |
| PMC3870290__F4 | Potential mechanism of AICD-mediated gene regulation |
| PMC3870411__F1 | TNF Signals through TNFR1 and TNFR2 receptors (A) but abnormalities in this signaling pathway in autoimmunity (B) can favor a pathway of selective apoptosis due to a variety of protein signaling defects |
| PMC3870464__F2 | Protein components of the pheromone response network constructed by the PCST approach |
| PMC3870610__F8 | Signaling pathway of the AMH protein |
| PMC3871217__F12 | Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways |
| PMC3871231__F2 | New and emerging HDAC inhibitors for cancer treatment |
| PMC3871277__F1 | Panitumumab and epidermal growth factor receptor (EGFR) signaling pathway |
| PMC3871617__F5 | NHE Isoform Switching and KChIP2 Upregulation in Aging Porcine Atria |
| PMC3871639__F5 | Inflammation Regulates TMPRSS6 Expression via STAT5 |
| PMC3871684__F1 | Microfluidic Generated EGF-Gradients Induce Chemokinesis of Transplantable Retinal Progenitor Cells via the JAK/STAT and PI3Kinase Signaling Pathways |
| PMC3871865__F1 | Photoreceptor cell death and rescue in retinal detachment and degenerations |
| PMC3871878__F2 | Hypoxia inducible factor pathway inhibitors as anticancer therapeutics |
| PMC3871884__F8 | Schematic diagram illustrating central role for ROS and Src in hypoxia-induced pY654-Beta-catenin/HIF1A formation and tumor EMT |
| PMC3871910__F7 | Proposed synergistic mechanisms for induction of mitotic cell death in endometrial cancer cells with mutant p53 |
| PMC3872233__F4 | Toll-like receptor 4 signaling pathway in alcohol consumption |
| PMC3872270__F2 | Many ways to inactivate the p53 pathway in cancer |
| PMC3872295__F1 | Mechanistic model to show how mechanical forces promote differentiation of fetal type II epithelial cells via release of soluble growth factors HB-EGF and TGFA with subsequent binding and activation of the EGFR and ERK signaling pathway |
| PMC3872778__F2 | Similarities between NAA synthesis and citrate synthesis |
| PMC3873541__F7 | Enriched canonical pathways of miRNA target genes |
| PMC3873642__F1 | A proposed model of the DNA-damage response pathway |
| PMC3873730__F3 | Transcriptome Analysis of Human Injured Meniscus Reveals a Distinct Phenotype of Meniscus Degeneration with Aging |
| PMC3874163__F8 | A simplified view of siRNA-enhanced DNA-mediated IFN-λ1 signalling pathway |
| PMC3874211__F4 | Network pathway analysis integrated the majority of proteins identified as changed on 2DE (), as shown in but did not include S-methyl-5`thioadenosine phosphorylase, and lamin B1 because of low scoring |
| PMC3874238__F2 | Insulin is the major hormone controlling critical energy functions such as glucose and lipid metabolism |
| PMC3874287__F1 | Deconvoluting the Obesity and Breast Cancer Link: Secretome, Soil and Seed Interactions |
| PMC3874316__F7 | Antcin C-induced upregulation of antioxidative gene expression via the Nrf2/ARE signaling pathway and suppression of AAPH-induced apoptosis in human hepatic HepG2 cells |
| PMC3874419__F1 | Signaling cross-talk at the various levels of EGFR/HER2 signaling pathways |
| PMC3874419__F4 | Cross-talk of EGFR/HER2 signaling with other pathways |
| PMC3874794__F2 | An outline of the GPI and GPI-anchored protein biosynthetic pathway |
| PMC3874812__F8 | Cav-1 phosphorylation-dependent LPS signaling pathway in mediating lung inflammation in endothelial cells |
| PMC3874981__F3 | Beta-catenin dependent and independent Wnt signaling pathways |
| PMC3874981__F4 | Schematic of Hedgehog signaling pathway |
| PMC3874981__F5 | NELL-1 signaling pathway |
| PMC3875243__F1 | Characterization of Negative Feedback Network Motifs in the TGFB Signaling Pathway |
| PMC3875397__F1 | FOXO transcription factors throughout T cell biology |
| PMC3875403__F6 | MDA-7 interferes with tumor promoting pathways |
| PMC3875462__F1 | Regulation of the mTOR signaling pathway |
| PMC3875463__F1 | MTOR pathway and epilepsy |
| PMC3875464__F3 | PKG regulation of TRPC current and signaling |
| PMC3875633__F4 | Invasion gene signaling networks (GSNs) of (A) chronic CNT-exposed and (B) chronic asbestos-exposed MeT5A cells |
| PMC3875667__F2 | Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival |
| PMC3875676__F4 | High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells |
| PMC3875720__F4 | Upregulated Genes Encode Key Enzymes in Central Carbon Metabolism.Steps in the glyoxylate cycle (A), gluconeogenesis (B), and oxidative pentose phosphate pathway (C) are shown |
| PMC3875779__F2 | Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis. |
| PMC3875780__F3 | Human intestinal innate myeloid cells |
| PMC3875822__F1 | Metabolic model of C4 assimilation, rates of reaction, and net fluxes between and |
| PMC3875828__F1 | Asp and aromatic amino acid biosynthetic pathways in plants |
| PMC3875894__F1 | Pathway Protection Loop |
| PMC3875894__F3 | mTOR signaling pathway (#hsa04150) |
| PMC3875894__F4 | Antigen processing and presentation (APP) pathway (#hsa04612) |
| PMC3875938__F1 | The mechanisms of Wnt/Beta-catenin pathway repression by 1,25(OH)2D3 in human colon carcinoma cells |
| PMC3875949__F1 | Regulation of metabolism in maligant gliomas |
| PMC3876023__F1 | Suppression of regulatory B cells identified in human and animal |
| PMC3876077__F1 | Schematic overview of the transforming growth factor (TGF)B signaling pathway |
| PMC3876432__F3 | IL-6-STAT3 signaling and premature senescence |
| PMC3876433__F1 | Oxidative metabolism in cancer |
| PMC3876437__F1 | A non-canonical JAK-STAT pathway in IFN therapy of poxvirus infection and multiple sclerosis |
| PMC3876736__F6 | TSC-mTOR pathway regulates macrophage polarization |
| PMC3876738__F2 | Therapeutic targets in cancer cell metabolism and autophagy |
| PMC3876931__F10 | Differential regulation of the REGG-proteasome pathway by p53/TGFB signalling and mutant p53 in cancer cells |
| PMC3877020__F4 | UVA and UVB Irradiation Differentially Regulate microRNA Expression in Human Primary Keratinocytes |
| PMC3877165__F2 | Schematic view of integration of TCR signal transduction with diverse components of the actin polymerization machinery |
| PMC3877388__F6 | Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling |
| PMC3877547__F9 | Schematic model of cancer-derived IgG to enhance cell growth and proliferation through inducing the production of a low level of ROS |
| PMC387762__F5 | CREB pathway and possible positions of proteins whose genes contain CREB1 binding sites |
| PMC3877660__F1 | An overview of EGFR and Wnt/Beta-catenin signaling |
| PMC3877685__F2 | Automatic Context-Specific Subnetwork Discovery from Large Interaction Networks |
| PMC3877719__F1 | Analysis with NIH DAVID, Princeton GO term finder and Ingenuity Pathway Analysis yield similar gene enrichments, biological processes and pathways.The high confidence hit list was also analyzed by IPA for biological pathway enrichment |
| PMC3877826__F9 | Model of Interaction with the b-Dependent Developmental Control Pathway.(A) Filamentous growth is triggered by bE/bW-dependent induction of rbf1 expression |
| PMC3877845__F1 | mTOR signalling pathway |
| PMC3877903__F9 | Fumigaclavine C-induced apoptosis in MCF-7 breast cancer cells through the mitochondrial pathway |
| PMC3877975__F5 | Coordinately up-regulated genes of chemokine signaling pathway in monocytes from the VIR group (VIR versus BDL) |
| PMC3878201__F4 | miR-34a mediates paclitaxel resistance via both direct and indirect mechanisms |
| PMC3878307__F1 | TMEFF2 AND SARDH COOPERATE TO MODULATE ONE CARBON METABOLISM AND INVASION OF PROSTATE CANCER CELLS |
| PMC3878444__F2 | The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro. |
| PMC3878444__F3 | The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro. |
| PMC3878444__F4 | Upstream regulators and their target molecules in datasets as identified by Ingenuity Pathway Analysis (IPA) |
| PMC3878444__F6 | The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro. |
| PMC3879068__F3 | Networks showing metabolic pathways differentially modulated between H and L groups |
| PMC3879372__F10 | Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells |
| PMC3879613__F7 | Biological functions regulated by miR-378 and miR-378* |
| PMC3879708__F2 | Upstream nutrient signaling to mTORC1 and AMPK |
| PMC3879958__F1 | Regulating the Regulator: Post-Translational Modification of Ras |
| PMC3880197__F2 | Reactive oxygen species in cancer |
| PMC3880216__F5 | Schematic diagram |
| PMC3880276__F9 | Rapamycin Ameliorates Inflammation and Fibrosis in the Early Phase of Cirrhotic Portal Hypertension in Rats through Inhibition of mTORC1 but Not mTORC2 |
| PMC3880284__F4 | Human Mammospheres Secrete Hormone-Regulated Active Extracellular Vesicles |
| PMC3880546__F1 | Physiological regulation of the mTOR pathway |
| PMC3880546__F2 | Pathological regulation of the mTOR pathway in neurological disease |
| PMC3880642__F1 | Smoking and microRNA dysregulation: a cancerous combination |
| PMC3880796__F2 | TRAIL on Trial: Preclinical advances for cancer therapy |
| PMC3880903__F8 | Fasting Induces Nuclear Factor E2-Related Factor 2 and ATP-Binding Cassette Transporters via Protein Kinase A and Sirtuin-1 in Mouse and Human |
| PMC3880999__F1 | Molecular details of BAFF/BAFFR-mediated activation of NFKB2 signaling pathway |
| PMC3881016__F5 | Pathway analysis of iron deficiency associated chlorosis |
| PMC3881294__F2 | Regulating intestinal function to reduce atherogenic lipoproteins |
| PMC3881602__F1 | Interplay between regulatory T cells and metabolism in immune regulation |
| PMC3881972__F1 | Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals: a review of recent research |
| PMC3882126__F1 | Autism genes keep turning up chromatin |
| PMC3882141__F1 | Regulatory Networks and Complex Interactions between the Insulin and Angiotensin II Signalling Systems: Models and Implications for Hypertension and Diabetes |
| PMC3882377__F6 | Schema of our hypothesis |
| PMC3882431__F6 | Schematic representation of the proposed pathway by which deficiency of FXR activates the STAT3 signaling pathway in the liver |
| PMC3882437__F4 | Perturbed pattern of genes in the peroxisome proliferation activator receptor (PPAR) signaling pathway by DEX administration (ethanol plus DEX vs |
| PMC3882527__F5 | Ingenuity pathway analysis (IPA)-identified top networks affected by Cd-induced oxidation of proteins |
| PMC3882535__F3 | Novel GPCR-based signaling mechanisms in ASM |
| PMC3882682__F8 | Canonical pathways |
| PMC3882710__F8 | The potential role of MuRF1 in atrophy induced gene expression pathways |
| PMC3882755__F8 | A Receptor-Specific Function for Notch2 in Mediating Vascular Smooth Muscle Cell Growth Arrest Through p27kip1 |
| PMC3882864__F1 | The variety of stimuli that can up-regulate NKG2D and DNAM-1 ligands |
| PMC3883113__F6 | Neurodegenerative diseases and widespread aggregation are associated with supersaturated proteins |
| PMC3883350__F1 | VIP tunes immune and inflammatory response by regulating multiple signaling pathways |
| PMC3883721__F1 | Phosphoinositide-3 kinase (PI3K) is a heterodimer consisting of p85 and p110 subunits |
| PMC3883963__F3 | HMGB1-TLR4 signaling mediates liver I/R injury |
| PMC3884200__F5 | Effects of CYP2S1 depletion on mTOR signaling |
| PMC3884575__F2 | Schematic representation of complement-mediated effects on T cells and APCs |
| PMC3884689__F7 | Modulators of the microRNA biogenesis pathway via arrayed lentiviral enabled RNAi screening for drug and biomarker discovery |
| PMC3884931__F1 | Mammalian target of rapamycin (mTOR) signaling pathway regulation |
| PMC3885718__F6 | Resveratrol Induces Vascular Smooth Muscle Cell Differentiation through Stimulation of SirT1 and AMPK |
| PMC3885992__F5 | Polarization of immune cells in the tumour environment by TGFB |
| PMC3886260__F2 | Lck is a central node in the T cell receptor signaling pathway |
| PMC3886269__F4 | Inducible antioxidant defense regulated by Nrf2/Keap1 and the antioxidant response element |
| PMC3886588__F1 | Targeting the Th17 pathway |
| PMC3886798__SF3 | Overview of the treatments in the context of previous results obtained with a test system based on the fluorescent reporter protein H 6-GFP-BD-CVIL in transgenic tobacco BY-2 cells |
| PMC3886801__F1 | STAT-3: A Molecular Hub for Signaling Pathways in Gliomas |
| PMC3886801__F2 | STAT-3: A Molecular Hub for Signaling Pathways in Gliomas |
| PMC3886813__F1 | NFKB and STAT3 signaling in glioma: targets for future therapies |
| PMC3886813__F2 | NFKB and STAT3 signaling in glioma: targets for future therapies |
| PMC3887194__F13 | Schematic modeling of the TcpB inhibition of TLR4 signaling |
| PMC3887202__F1 | De novo synthesis of steroids, oxysterols, and bile acids from cholesterol |
| PMC3887408__F1 | Interactions of the Ras/PI3K/PTEN/Akt/mTOR and Ras/Raf/MEK/ERK pathways with GSK-3 |
| PMC3887408__F5 | Novel approaches of targeting signaling pathways in leukemia |
| PMC3887453__F2 | Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress |
| PMC3887674__F1 | Factors influencing the reprogramming of unipotent SSCs into pluripotent stem cells |
| PMC3887753__F1 | Sequential pathway leading to renal ischemia-reperfusion injury |
| PMC3887856__F1 | Two branches of pathway upstream of mTORC1 |
| PMC3887856__F3 | SH3BP4 is a potential tumor suppressor functioning in the amino acid-mTORC1 pathway |
| PMC3887879__F1 | MTOR signaling pathway |
| PMC3887879__F3 | Nutrient signaling to mTORC1 |
| PMC3887911__F2 | Activation mechanism of Orai1 and STIM1 |
| PMC3887911__F3 | Interacting partners and posttranslational modification of Orai1 and STIM1 |
| PMC3887911__F4 | CRAC channel regulation by multiple Ca2+-sensing molecules in the ER and cytoplasm |
| PMC3887921__F2 | Regulation of autophagy by nutrient signals |
| PMC3887939__F1 | Signaling mechanisms proposed for the mammalian autophagy pathway |
| PMC3888279__F3 | Regulation of hypoxia-inducible factor (HIF)-A expression or stabilization by pathways other than hypoxia |
| PMC3888285__F2 | Liver responds to iron signals to regulate hepcidin production |
| PMC3888473__F3 | Top genes from SNP comparative analysis |
| PMC3888473__F4 | Pathway analysis on SNPs that affect gene expression and drug response |
| PMC3888787__F1 | Bile acid synthesis occurs by two pathways, the classic 'neutral' pathway and the alternative 'acidic' pathway |
| PMC3888837__F1 | Sphingolipid regulation of ezrin, radixin, and moesin protein families: implications for cell dynamics, |
| PMC3888876__F2 | MONOGENIC AUTOINFLAMMATORY DISEASES: DISORDERS OF AMPLIFIED DANGER SENSING AND CYTOKINE DYSREGULATION |
| PMC3888942__F6 | Axon navigation pathway targeting by miRNAs that differentially associate with Ago2 in an activity-dependent manner |
| PMC3889250__F1 | The BDNF signaling network |
| PMC3889251__F1 | BMP2 signaling pathway resulting in osteogenesis or adipogenesis |
| PMC3889251__F9 | New proposed model of BMP2-induced C2C12 cells differentiation |
| PMC3889252__F4 | TGFB1 Smad signaling pathway contributes to HTS |
| PMC3889255__F1 | CRH signaling pathway - This map represents the NetPath reactions of CRH signaling pathway |
| PMC3889256__F7 | Rsu1 is a critical component for regulation of p38 Map kinase signaling from the IPP complex |
| PMC3889478__F1 | Comparison of in vivo (left) and in vitro (right) signaling support to the intestinal stem cell |
| PMC3889557__F10 | Schematic representation of eHsp90A signaling pathway |
| PMC3889573__F1 | HOG signaling pathway in C |
| PMC3889573__F2 | Ras, cAMP/PKA, and MSIL signaling pathways in C |
| PMC3889649__F5 | GLI1 target genes converge on a regulatory pathway that suggests roles in cell proliferation, survival and genomic stability |
| PMC3889683__F3 | Schematic presentation of potential signaling network of HER2-NFKB-PI3 K-Akt-STAT3 |
| PMC3889810__F6 | Whole genome and gene set enrichment analysis of cells expressing mutants of neuroserpin show an upregulation of the cholesterol pathway when polymers are expressed |
| PMC3890408__F2 | Cooperating mutational events in MYC-driven lymphomagenesis and novel therapeutic opportunities.Notes: Continuous MYC expression is required for BL cell survival, as demonstrated by the apoptotic effect of the MYC inhibitor 10058-F4 on BL cell lines |
| PMC3890531__F4 | IGF signaling pathway |
| PMC3890531__F5 | VEGF and NOTCH signaling pathways |
| PMC3890654__F1 | Toll-like receptor-4 signaling pathway |
| PMC3890654__F2 | Negative regulators of toll-like receptor-4 signaling pathway by Lactobacillus jensenii TL2937 in porcine intestinal epithelial cells and antigen presenting cells |
| PMC3890705__F6 | Proangiogenic mechanisms activated in the omentum during transcoelomic EOC metastasis in the presence of anti-VEGF therapy |
| PMC3890716__F2 | Schematic for the putative biosynthetic pathways of three major classes of active compounds in I |
| PMC3890879__F8 | Model of mevalonate and Hippo pathways regulating YAP-controlled RHAMM transcription and cancer cell motility |
| PMC3891052__F3 | Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns to Shape the Cancer Genome |
| PMC3891116__F2 | Essential cell signaling pathways for prostate cancer (PCa) development and crosstalks between themThe interaction of circulating androgens (T/DHT) with AR is critical for PCa growth |
| PMC3891361__F8 | Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA |
| PMC3891517__F3 | Possible mechanisms of opioid receptor-mediated influence of morphine on tumor growth |
| PMC3891587__F2 | GENETIC CONTROL OF CANDIDA ALBICANS BIOFILM DEVELOPMENT |
| PMC3891682__F2 | Putative miRNAs for the diagnosis of dyslexia, dyspraxia, and specific language impairment |
| PMC3891875__F1 | Wnt signaling |
| PMC3892099__F8 | Summary of parthenolide-induced signaling pathway in NSCLC cell lines |
| PMC3892554__F2 | TRB3 at the crossroads of ER stress and mTORC function |
| PMC3892798__F1 | PD-1 in T-cell activation, exhaustion, and effector function |
| PMC3892938__F2 | A schematic representation of IL-12 family cytokines and the corresponding receptors and JAK-STAT signaling pathways |
| PMC3893124__F1 | Current and Future Therapies for Hepatitis C Virus Infection |
| PMC3893527__F4 | Signal pathways involved in renal IRI |
| PMC3893574__F1 | MiRNAs involved in the regulation of the IGF-1/Akt pathway and myostatin signaling |
| PMC3893888__F4 | Signal transduction pathways leading to increased HIF-1A protein levels |
| PMC3893930__F2 | Ewing's Sarcoma: Overcoming the Therapeutic Plateau |
| PMC3893993__F3 | RAS-mitogen-activated protein kinase signaling pathway |
| PMC3894150__F1 | Central Role of the PPARγ Gene Network in Coordinating Beef Cattle Intramuscular Adipogenesis in Response to Weaning Age and Nutrition. |
| PMC3894167__F1 | Is Non-Homologous End-Joining Really an Inherently Error-Prone Process? |
| PMC3894232__F2 | JAK2-STAT5B pathway and osteoblast differentiation |
| PMC3894232__F3 | JAK2-STAT5B pathway and osteoblast differentiation |
| PMC3894494__F7 | Proposed model of heme-induced stasis |
| PMC3894710__F2 | Autophagy: A Crucial Moderator of Redox Balance, Inflammation, and Apoptosis in Lung Disease |
| PMC3894712__F4 | Autophagy in Kidney Health and Disease |
| PMC3894810__F5 | New insights into host-pathogen interactions during Entamoeba histolytica liver infection |
| PMC3895605__F2 | Possible signalling pathways involved in enteric neurogenesis by a 5-hydroxytryptamine 4 receptor (5-HT4R) agonist mosapride citrate (MOS) |
| PMC3895844__F2 | Ephrin receptor signalling is the most significant canonical pathway in an olanzapine-treated cerebellum |
| PMC3895844__F3 | Dopamine-DARPP32 feedback in cAMP signalling is a significant canonical pathway in an olanzapine-treated hippocampus |
| PMC3895871__F1 | TWEAK/Fn14 Signaling |
| PMC3895947__F4 | Wide variety of glycoconjugates such as heparin sulfate proteoglycan (HSPG), chondrotin sulfate proteoglycan (CSPG), N-glycosylated cystatin C, and galectins-1 are involved in signaling pathways inducing proliferation and self-renewal of NSCs |
| PMC3896120__F8 | Schematic diagram of EGFR-invadopodia signaling pathways altered by Abl inhibition in HNSCC |
| PMC3896626__F1 | Interaction among differentially modulated genes in the cell cycle biochemical pathway, using KEGG, after hgf-FNDF-LC50 and SCFA-LC50 treatments |
| PMC3896626__F2 | Interaction among differentially modulated genes in the apoptosis biochemical pathway, using KEGG, after hgf-FNDF-LC50 and SCFA-LC50 treatments |
| PMC3896667__F5 | Significantly altered pathway in primary tumor |
| PMC3896749__F9 | Hypothesis for the development of tactile allodynia following nerve injury |
| PMC3896784__F8 | Model of FTO regulation of leptin action and glucose homeostasis through the LepRb-STAT3 signaling pathway |
| PMC3896945__F1 | Pharmacological approaches to restore mitochondrial function |
| PMC3897216__F2 | The possible mechanisms of action of Wu-Ling-San, Danggui-Buxue-Tang, or Danggui-Shaoyao-San on the amelioration of hyperglycemia-mediated renal injury in STZ-diabetic rats |
| PMC3897220__F9 | Concept map of Whi5 function |
| PMC3897272__F1 | Eicosanoid biosynthetic pathway |
| PMC3897553__F8 | Neural Epidermal Growth Factor-Like Like Protein 2 (NELL2) Promotes Aggregation of Embryonic Carcinoma P19 Cells by Inducing N-Cadherin Expression |
| PMC3897565__F1 | Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells |
| PMC3897622__F6 | p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line |
| PMC3897773__F7 | Regulation of Amyloid Precursor Protein Processing by Serotonin Signaling |
| PMC3898176__F2 | Toll pathway |
| PMC3898353__F1 | Complement activation pathways |
| PMC3898671__F2 | Synthesis of the C5 isoprenoid precursors IPP and DMAPP |
| PMC3898811__F7 | Schematic diagram as summary of the present investigation |
| PMC3899118__F5 | Genome Wide Expression Analysis Suggests Perturbation of Vascular Homeostasis during High Altitude Pulmonary Edema |
| PMC3899188__F1 | Regulation of lysosome biogenesis and functions in osteoclasts |
| PMC3899800__F3 | BRCA1 and its toolbox for the maintenance of genome integrity |
| PMC3899875__F4 | MiR-148b in the mTOR signalling pathway |
| PMC3899875__F5 | MiR-15a in the AD pathway |
| PMC3899918__F2 | Jak-STAT Signaling Pathway from KEGG (ID: hsa04630) overlaid with log2 fold change values using PathVisio indicating up (red) or downregulation (blue) following ART |
| PMC3899934__F2 | Farnesoid X receptor-Acting through bile acids to treat metabolic disorders |
| PMC3899946__F2 | Radiation-Induced Bystander Response: Mechanism and Clinical Implications |
| PMC3899953__F6 | A model for the role of ATP-mediated interaction between Rtg2 and Mks1 in ATP homeostasis |
| PMC3899964__F1 | Discriminating Gene Expression Signature of Radiation-Induced Thyroid Tumors after Either External Exposure or Internal Contamination. |
| PMC3899973__F1 | Canonical signaling of muscarinic receptors |
| PMC3900298__F5 | New immunological approaches in treating and diagnosing CNS diseases |
| PMC3900493__F1 | Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms |
| PMC3900493__F2 | Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms |
| PMC3900493__F3 | Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms |
| PMC3900493__F4 | Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms |
| PMC3900498__F1 | Yin and Yang of PI3K vs PTEN in the regulation of beta cell proliferation |
| PMC3900522__F3 | Fibroblast Growth Factor Receptor 3 Interacts with and Activates TGFBeta-Activated Kinase 1 Tyrosine Phosphorylation and NFKB Signaling in Multiple Myeloma and Bladder Cancer |
| PMC3900881__F3 | Sugar for the brain: the role of glucose in physiological and pathological brain function |
| PMC3901108__F3 | Summary diagram showing the role of ATG16L1 and NOD2 in the autophagy pathway and the defects observed when Crohn's disease (CD) associated mutations are present |
| PMC3901112__F1 | Autophagy is initiated by stimuli that activate the phosphatidylinositol 3-phosphate kinase, Vps34 |
| PMC3901115__F2 | Autophagy pathway: Molecular features |
| PMC3901118__F3 | Overview of the Ras/PKA pathway and relevant regulatory connections involved in the yeast pseudohyphal growth and autophagy responses |
| PMC3901146__F1 | Regulation of cellular stress-induced cell death pathways by IAPs |
| PMC3901146__F3 | Role of IAPs in DNA damage response |
| PMC3901350__F1 | Noncoding RNAs in DNA Repair and Genome Integrity |
| PMC3901523__F3 | Signaling pathways for inner ear proliferation and differentiation |
| PMC3901678__F6 | Mining Gene Expression Data for Pollutants (Dioxin, Toluene, Formaldehyde) and Low Dose of Gamma-Irradiation |
| PMC3901886__F1 | Schematic representation of ligand-activated AHR signaling |
| PMC3901996__F2 | Transmembrane signaling of IL-6, which is a major growth factor for MM |
| PMC3902114__F1 | Targeting inflammatory cytokines-androgen receptor (AR) signaling with ASC-J9® to better battle prostate cancer progression |
| PMC3902172__F7 | In vivo Mapping of Notch Pathway Activity in Normal and Stress Hematopoiesis |
| PMC3902304__F1 | TWEAK/Fn14 signaling cascade |
| PMC3902842__F3 | Molecular mechanisms involved in leptin receptor signaling in the hypothalamus |
| PMC3902845__F2 | Multiple changes in gene expression influence KRAS activity, the KRAS downstream pathway and cell growth occur during development of a "mature" PDAC cell |
| PMC3903161__F1 | Steps of autophagy pathway activation |
| PMC3903252__F7 | Schematic illustration of the TGFB/ENaC pathway in a generalized alveolar epithelial cell monolayer, described in this study |
| PMC3903278__F8 | Cofilin regulating actin dynamics and initiating HSV-1 entry |
| PMC3903477__F1 | Characterization of Cyanobacterial Hydrocarbon Composition and Distribution of Biosynthetic Pathways |
| PMC3903560__F7 | Ingenuity pathways analysis |
| PMC3903702__F1 | EZH2 takes the stage when BRCA1 loses |
| PMC3904234__F1 | Interleukin-17 (IL-17) and IL-17 receptor family members and their biological roles |
| PMC3904369__F1a | Charity begins at home: non-coding RNA contributes to DNA repair |
| PMC3904428__F1 | Ral GTPase pathway in metastatic bladder cancer: key mediator and therapeutic target |
| PMC3904431__F3 | Targeting MicroRNAs in Cancer: Rationale, Strategies and Challenges |
| PMC3904516__F8 | LPS-Stimulated Inflammatory Environment Inhibits BMP-2-Induced Osteoblastic Differentiation Through Crosstalk Between TLR4/MyD88/NFKB and BMP/Smad Signaling |
| PMC3904625__F8 | Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation |
| PMC3904630__F9 | OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness |
| PMC3904668__F1 | CD180 is a close relative of TLR4 and together with BCR signaling can promote B-cell activation and differentiation |
| PMC3905229__F2 | Wnt/GSK- 3B pathway |
| PMC3905242__F1 | MRE11 complex: starting from the ends |
| PMC3905242__F4 | MRE11 complex: starting from the ends |
| PMC3905281__F5 | Wnt signalling pathway in developing muscle-less humeri |
| PMC3905285__F4 | Possible pathways for lipoic acid attachment to mitochondrial Alpha-ketodehydrogenase apoenzymes |
| PMC3905307__F1 | Canonical (A) and noncanonical (B) Wnt signaling pathway represented by KEGG analysis |
| PMC3906243__F6 | Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets |
| PMC3906322__F2 | STAT2 and IRF9 |
| PMC3906328__F1 | IL-17 signaling and A20 |
| PMC3906332__F4 | Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells |
| PMC3906547__F1 | Reverse cholesterol transport pathway delivers free cholesterol from macrophages or other cells to the liver or intestine for excretion |
| PMC3906548__F1 | AT2R-mediated molecular pathways involved in tissue injury |
| PMC3906588__F1 | UPR response underling memory consolidation in Alzheimer's disease |
| PMC3907011__F5 | Schematic diagram of the Bcl-w-induced signaling pathway by the activation of Sp1 |
| PMC3907060__F4 | Analyses of differentially expressed genes regulated by fasting in all three tissues revealing an involvement of p53 and Srebp signaling pathway |
| PMC3907121__F1 | Cardiovascular Effects of Erythropoietin: An Update |
| PMC3907751__F1 | ROS generation and its effect on angiogenesis |
| PMC3908275__F5 | Interaction of MSCs and HSCs |
| PMC3908331__F9 | KEGG mapping for cell cycle pathway |
| PMC3908416__F8 | Panx3 signaling pathways inhibit osteoprogenitor cell proliferation and promote cell cycle exit |
| PMC3909012__F7 | Cell Surface Area and Membrane Folding in Glioblastoma Cell Lines Differing in PTEN and p53 Status. |
| PMC3909253__F9 | Bacteria Induce Prolonged PMN Survival via a Phosphatidylcholine-Specific Phospholipase C- and Protein Kinase C-Dependent Mechanism |
| PMC3909817__F4 | Potential mechanisms of TGF-Beta-induced upregulation of Nox4 gene expression |
| PMC3910266__F2 | NOD1 signaling and interactions with Rho GTPases and NFATc |
| PMC3910345__F3 | Molecular regulation of hepcidin by iron and inflammation |
| PMC3910500__F6 | Canonical PI3K and MAPK pathway activation determined by reverse phase protein arrays and compared between GBM subclasses: Proneural (P, purple, n=55) and Mesenchymal (M, red, n=45) |
| PMC3910515__F7 | TGFB signaling at the BBB during acute peripheral inflammatory pain |
| PMC3911027__F4 | Metabolic potential of Acidilobus-like populations from YNP deduced from coding sequences obtained from metagenome assemblies |
| PMC3911241__F4 | Examples of network refinements and reannotations |
| PMC3911500__F7 | Schematic model for how S6K1 inhibits TLR2- or TLR4-mediated signaling pathways |
| PMC3911547__F12 | Schematic diagram depicting the diverse outcomes of KSHV-induced 5LO and LTB4 in ECs and the consequences and roles of KSHV in viral pathogenesis |
| PMC3911663__F5 | Summary model for rAdV DNA sensing |
| PMC3912139__F6 | GNAS Mutation Found in Pancreatic Intraductal Papillary Mucinous Neoplasms Induces Drastic Alterations of Gene Expression Profiles with Upregulation of Mucin Genes |
| PMC3912166__F1 | Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs |
| PMC3912412__F6 | Interaction of CLL cells and the lymph node microenvironment |
| PMC3912487__F1 | The sphingolipid rheostat in AD context |
| PMC3912696__F1 | Role of cytokines in Th1 and Th2 differentiation of lymphocytes |
| PMC3912738__F1 | IGF signaling involvement in EMT |
| PMC3912738__F3 | The interplay between the canonical Wnt/Beta-catenin pathway and IGF signaling |
| PMC3912738__F4 | The cross-talks between the Notch and the IGF signaling |
| PMC3912738__F5 | Proposed model for the interaction between Shh and IGF signaling |
| PMC3912804__F1a | Hedgehog signaling pathways in vertebrates-without hedgehog ligand |
| PMC3912804__F2a | Hedgehog signaling pathway in cancers-Type I-Ligand-independent cancers |
| PMC3912804__F2b | Hedgehog signaling pathway in cancers -Type II- Autocrine Ligand-dependent cancers |
| PMC3912804__F2c | Hedgehog signaling pathway in cancers -Type III- Paracrine Ligand-dependent cancers |
| PMC3912804__F2d | Hedgehog signaling pathway in cancers -Type IIIb-Reverse Paracrine Ligand-dependent cancers |
| PMC3913057__F3 | ErbBs/EGFR(s) signaling pathways |
| PMC3913083__F1 | Signaling pathways involved in the control of skeletal muscle atrophy and hypertrophy |
| PMC3913210__F1 | Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction |
| PMC3913210__F2 | Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction. |
| PMC3913495__F1 | IL-6 exerts its pleiotropic activity by activation of gp130 through its binding to transmembrane or soluble IL-6 receptor |
| PMC3913524__F1 | The PI3K/Akt/mTOR pathway substrates and associated cellular functions |
| PMC3913761__F2 | Emerging roles of store-operated Ca2+ entry through STIM and ORAI proteins in immunity, hemostasis and cancer |
| PMC3913901__F2 | cIAP1/2 regulation of TNFAlpha-induced canonical NFKB pathway activation and suppression of default death pathways |
| PMC3913901__F3 | cIAP1/2 regulation of TWEAK-induced non-canonical NFKB pathway activation |
| PMC3913902__F4 | Induction of NLRP3 inflammasome complex by the inorganic crystal HZ |
| PMC3913938__F7 | Suggested mechanisms of synergistic cytotoxicity of [Gem+Clo+Ed] combination in lymphoma cells based on the previously reported data and our present results |
| PMC3913963__F5 | Beta-adrenergic signaling modulates multiple cellular processes in tumor progression and metastasis |
| PMC3913970__F1 | BCR/BTK signaling pathway |
| PMC3914023__F3 | A model of the EZH2 functional switch from a polycomb repressor to a transcriptional activator in castration-resistant prostate cancer |
| PMC3914352__F10 | Flow diagram representing the molecular interactions in the Toll-like receptor signaling pathway (from KEGG database) |
| PMC3914444__F2 | Scheme of PI3K/PTEN/AKT signaling network activated by heterodimerization of HER2/HER3 receptors induced by heregulin (HRG) and inhibited by pertuzumab, 2C4 |
| PMC3914472__F1 | Metabolic pathway of the glycine cleavage enzyme system and the synthesis of its lipoate cofactor |
| PMC3915289__F1 | The kynurenine metabolic pathway |
| PMC3915522__F5 | Ras oncogenes: split personalities |
| PMC3915736__F2 | Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy |
| PMC3916405__F1 | Distinct Antiviral Responses in Pluripotent versus Differentiated Cells |
| PMC3916571__F7 | The signaling transduction throughout integrin engagement by Cp aged under oxidative conditions |
| PMC3916982__F2 | Crosstalk of signaling pathways in breast cancer and the potential clinical therapeutic targets |
| PMC3917155__F4 | Inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to AMPK activation and anti-tumor activity |
| PMC3917325__F1 | Chondroitin sulfate and HS biosynthesis |
| PMC3917351__F1 | Ca2+ transport remodelling in promotion of cancer cell proliferation |
| PMC3917351__F2 | Ca2+ transport remodelling in conferring apoptosis resistance in cancer cells |
| PMC3917351__F3 | Ca2+ transport remodelling in the promotion of cancer cell metastasis |
| PMC3917351__F4 | Ca2+ transport remodelling in tumour vascularization |
| PMC3917352__F1 | Major metabolic pathways in tumour cells |
| PMC3917509__F1 | The multiple roles of protein ubiquitylation |
| PMC3917548__F1 | The interleukin (IL)-21 receptor signaling pathway |
| PMC3917750__F1 | Dual regulatory effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) on neuronal apoptosis |
| PMC3917856__F6 | NRF2-KEAP1 Pathway Is an Early Responsive Gene Network in Arsenic Exposed Lymphoblastoid Cells |
| PMC3918130__F5 | Adenovirus elicits IFNAB production by a novel viral induction pathway |
| PMC3918413__F4 | Transforming growth factorB (TGFB) signalling pathway |
| PMC3918842__F2 | Pathways for the synthesis of phospholipids and their interconnection |
| PMC3918861__F2 | Induction of apoptosis |
| PMC3919142__S1 | Proposed biosynthetic pathway of stenothricin |
| PMC3919163__F2 | LPS receptor signaling pathways |
| PMC3919531__F1 | The Intertwined Roles of Transcription and Repair Proteins. |
| PMC3919568__F7 | Integrated metabolic pathway of BCAA metabolism |
| PMC3919687__F5 | Kinetic changes in gene expression of selected components of the Wnt/Beta-catenin signaling pathway in aging CD8+ T cells |
| PMC3919687__F6 | Kinetic changes in gene expression of selected components of Th2 responses |
| PMC3919808__F9 | Pathophysiology of Acute Kidney Injury |
| PMC3919979__F9 | CNP action in the SRG |
| PMC3920008__F4 | Novel regulatory pathway of intracellular lipid homeostasis |
| PMC3920129__F3 | TLR ligands/DAMPs, cellular location, and signaling in the vasculature |
| PMC3920756__F6 | Single Nucleotide Polymorphisms in MicroRNA Binding Sites of Oncogenes: Implications in Cancer and Pharmacogenomics |
| PMC3920940__F7 | Diagram showing the model proposed for the association of EMT, CSCs and the PI3K/Akt/mTOR signaling pathway in CaP radioresistance and the effect of possible action of BEZ235 on radiosensitivity |
| PMC3920945__F3 | Oncogenic and tumor suppressive autophagic pathways involved in miRNAs |
| PMC3920946__F1 | Serine, one-carbon cycle, glycine synthesis (SOG) pathway |
| PMC3921546__F1 | Representation of epidermal growth factor receptor pathway in response to therapy with anti-epidermal growth factor receptor inhibitors in wild-type and mutant patients |
| PMC3921548__F1 | Overview of arachidonic acid metabolism |
| PMC3921549__F1 | Carcinogenetic pathway and classification of colorectal cancer |
| PMC3921899__F1 | Lipid signals and insulin resistance |
| PMC3922035__F5 | Protein interaction network analysis of the up-regulated proteins in M |
| PMC3922094__F2 | Pancreatic cancer pathway diagram |
| PMC3922145__F3 | Differential expression of mTOR and HIF-1A pathways between leiomyoma, HLRCC and leiomyosarcoma |
| PMC3922160__F9 | Proposed model integrating viral and host biomarkers for disease severity and the effect of IFNB in HAM/TSP |
| PMC3922885__F7 | RhoC Regulates Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma by Overexpressing IL-6 and Phosphorylation of STAT3 |
| PMC3923149__F2 | Co-regulation of hepatic wound healing and regenerative responses via TWEAK- and LTBeta-mediated cellular cross-talk |
| PMC3923157__F2 | Tumor necrosis factorA and its osteoblastogenesis paradoxical effects |
| PMC3923158__F2 | Components that determine the establishment and tolerance-inducing capacity of tolerogenic effector DCs |
| PMC3923659__F2 | Structural Pathway of Interleukin 1 (IL-1) Initiated Signaling Reveals Mechanisms of Oncogenic Mutations and SNPs in Inflammation and Cancer |
| PMC3923659__F3 | Structural Pathway of Interleukin 1 (IL-1) Initiated Signaling Reveals Mechanisms of Oncogenic Mutations and SNPs in Inflammation and Cancer |
| PMC3923671__F1 | Impairment of T Cell Function in Parasitic Infections |
| PMC3923765__F2 | BiNA: A Visual Analytics Tool for Biological Network Data |
| PMC3923981__F7 | Cytosolic Functions of MORC2 in Lipogenesis and Adipogenesis |
| PMC3924162__F2 | Signaling pathways in PCSCs |
| PMC3924201__F1 | Control of the core Hippo signaling pathway through interacting upstream modules |
| PMC3924201__F2 | Hippo pathway-mediated regulation of cell lineage and pluripotency by adhesion and epithelial polarization in the early mouse embryo |
| PMC3924201__F4 | Two mechanisms for growth-factor-mediated regulation of the Hippo pathway: activation of Ras-MAPK signaling and activation of PI3K-PDK1 signaling |
| PMC3924248__F1 | Contribution of MTHFR, MTR and MTHFD1 in the folate metabolic pathway |
| PMC3924254__F7 | A6 integrin is the upstream regulator of the IGF-1R signaling pathway that enables low levels of caspase-3 activation to signal lens epithelial cell differentiation initiation |
| PMC3924561__F1 | Functional Relevance of Biased Signaling at the Angiotensin II Type 1 Receptor. |
| PMC3924581__F1 | AEG-1/MTDH/LYRIC promotes hepatocarcinogenesis |
| PMC3924769__F6 | DAF-12, a nuclear hormone receptor regulating development and lifespan |
| PMC3924780__F1 | Scaffolding Proteins: Not Such Innocent Bystanders |
| PMC3924811__F2 | Mechanosignaling in Bone Health, Trauma and Inflammation |
| PMC3924831__F2 | Apoptosis signaling under ER stress conditions |
| PMC3924851__F2 | New Function of Type I IFN: Induction of Autophagy |
| PMC3925027__F2 | Cytokines and their receptors regulating peripheral B-cell survival |
| PMC3925034__F1 | Schematic depiction of some of the Ca2+ channels, pumps and exchangers involved in Ca2+signalling in mammalian cells |
| PMC3925144__F11 | Autophagy Pathway Is Required for IL-6 Induced Neuroendocrine Differentiation and Chemoresistance of Prostate Cancer LNCaP Cells |
| PMC3925422__F3 | Breaking bad: Manipulation of the host response by Porphyromonas gingivalis |
| PMC3925679__F2 | Bile Acid Receptors in Non-alcoholic Fatty Liver Disease |
| PMC3925772__F7 | Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module |
| PMC3925795__F1 | Simplified schematic of macroautophagy in mammals |
| PMC3925803__F5 | Model showing elevated calcium and/or phosphate up-regulate HGF secretion and c-Met activation in conjunction with activation of the PI3K/Akt signalling pathway, leading to SMC mineralisation, which can be inhibited by AdNK4 treatment |
| PMC3926427__F1 | FGF/FGFR signaling pathway |
| PMC3926427__F4a | Targeting Fibroblast Growth Factor Pathways in Prostate Cancer |
| PMC3926505__F1 | Key organelles and proteins involved in cellular Cu homeostasis |
| PMC3926505__F3 | Roles of Cu in synaptic function |
| PMC3926670__F4 | Enriched pathway of the target gene union of radiation-response miRNAs |
| PMC3926678__F5 | Repetitive hypoxic preconditioning suppresses adaptive immune responses in resident B cells prior to stroke |
| PMC3926866__F1 | Diagram of the steroid hormone biosynthetic pathway in the human adrenal cortex |
| PMC3926884__F1 | Identification of a KRAS mutation in a patient with non-small cell lung cancer treated with chemoradiotherapy and panitumumab. |
| PMC3926887__F6 | Novel antioxidants are not toxic to normal tissues but effectively kill cancer cells |
| PMC3926967__F2 | Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections |
| PMC3927127__F2 | Cytokine-induced differentiation of human B cells in vitro: requirement for IL-21 signaling in vivo |
| PMC3927937__F2 | Mixed-lineage leukemia |
| PMC3927995__F2 | NFAT proteins activate an anergy-inducing program of gene expression |
| PMC3928023__F3 | Wiring and firing neuronal networks: Endocannabinoids take center stage |
| PMC3928074__F1 | Phase II Trials of Single Agent Anti-VEGF Therapy for Patients with Chronic Lymphocytic Leukemia (CLL) |
| PMC3928130__F2 | AMP-activated protein kinase (AMPK) beyond metabolism |
| PMC3928130__F4 | AMP-activated protein kinase (AMPK) beyond metabolism |
| PMC3928158__F1 | Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells |
| PMC3928173__F4 | Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis |
| PMC3928478__F2 | Inositol phosphates and Akt/PKB inhibition, a potential Akt/PKB feedback mechanism.Note: Adapted from Cell, 143(6), Manning BD, Insulin signaling: inositol phosphates get into the Akt, 861-863 |
| PMC3928643__F3 | IFNA/B and IL-4 centred pathway analysis |
| PMC3928643__F4 | IL-12 centred network analysis |
| PMC3928651__F2 | Solving Glycosylation Disorders: Fundamental Approaches Reveal Complicated Pathways. |
| PMC3928694__F2 | TLR signalling pathways: TLRs signal through myeloid differentiation primary response gene 88 (MyD88) or/and TIR-domain-containing adapter-inducing interferonB (TRIF)-dependent pathways |
| PMC3928697__F5 | Proposed pathway of CD33 siglec-mediated suppression of cellular function in Leishmania infection |
| PMC3928701__F1 | Normal signaling pathways and alterations in aged DCs in response to lipopolysaccharide (LPS)/bacteria (A), and in response to self antigen (DNA) |
| PMC3928706__F1 | Mechanism underlying GD T cell killing of tumours: GD T cell receptor (TCR) interacts with isopentenyl pyrophosphate (IPP) generated through the mevalonate pathway in tumours |
| PMC3928842__F1 | TLRs signaling pathway |
| PMC3929000__F1 | TRAIL signalling induces the extrinsic apoptotic pathway |
| PMC3929010__F10 | Reactive Oxygen Species in Inflammation and Tissue Injury |
| PMC3929010__F12 | Reactive Oxygen Species in Inflammation and Tissue Injury |
| PMC3929107__F1 | Regulation of Hippo pathway and implications for anticancer drug development |
| PMC3929246__F1 | Contribution of toll-like receptor signaling pathways to breast tumorigenesis and treatment. |
| PMC3929252__F1 | Estrogen, HER2 signalling, and the PI3K/Akt pathway in drug-resistant breast cancer.Notes: ER can activate gene transcription by nuclear translocatin following ligand binding (1) or as a result of receptor phosphorylation in the absence of ligand (2) |
| PMC3929326__F6 | Regulation of Hippo-Yap1/Taz signaling by polarity complexes |
| PMC3929401__F1 | Deficient Phosphorylation of Stat1 in Leukocytes Identifies Neutralizing Antibodies in Multiple Sclerosis Patients Treated with Interferon-Beta |
| PMC3929501__F1 | a) Digrammatic representation of follicle growth from the non-proliferating pool of primordial follicles |
| PMC3929669__F4 | PPARG signaling pathway during high-altitude vs sea-level pregnancy |
| PMC3929784__F8 | Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia |
| PMC3929886__F8 | Model for JMJD2B silencing on tumour suppression through DNA damage |
| PMC3930365__F5 | Top ranked network of genes altered in the newborn lung at 24h post-O3 exposure |
| PMC3930365__F6 | Second ranked network of genes altered in the newborn lung at 24h post-O3 exposure |
| PMC3930409__F10 | Epidermal growth factor (EGF-EGFR) signalling pathway in hepatocellular carcinoma (HCC) inflammatory microenvironment |
| PMC3930904__F1 | Global view on the intracellular proteome profile change in P |
| PMC3930975__F1 | The unfolded protein response pathway |
| PMC3931013__F3 | Wnt signaling pathway represented by KEGG analysis |
| PMC3931066__F7 | Activation of the ATR-signaling pathway during G1/G0 or G2-M phases of the cell cycle |
| PMC3931120__F7 | In Utero Exposure to Second-Hand Smoke Aggravates the Response to Ovalbumin in Adult Mice |
| PMC3931394__F2 | Transcriptomic analysis of isolated islets from GLU+IL-infused 6-month-old rats |
| PMC3931400__F2 | Signaling by EGF and PDGF in the regulation of Beta-cell proliferation |
| PMC3931400__F3 | Signaling by leptin, Wnt, and Beta-catenin in the regulation of Beta-cell proliferation |
| PMC3931425__F1 | Diagram of known egg activation pathways in Drosophila, Xenopus, and mouse |
| PMC3931461__F1 | Progress in molecular-based management of differentiated thyroid cancer |
| PMC3931462__F8 | Proteolytic cleavage of CDCP1 contributes to enhanced tumor cell survival and motility through the FAK and Akt signaling pathways downstream of complex formation between cleaved CDCP1 and B1 integrin |
| PMC3931732__F9 | CHC-1 and EPN-1 promote actin polymerization in response to CED-1 signaling |
| PMC3931971__F1 | Simplified schematic of common mutations in the Hedgehog signaling pathway leading to basal cell carcinoma from pathway activation (a), and therapeutic targets of this pathway (b) |
| PMC3932023__F2 | Exosome secretion in a cancer cell model |
| PMC3932028__F5 | Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells |
| PMC3932036__F5 | Akt signaling pathway |
| PMC3932224__F3 | Summary of regulatory networks centered by typical 2-Cys Prxs |
| PMC3932252__F2 | Autophagy is negatively regulated by the phosphatidylinositol 3-kinase (PI3 K)/Akt signaling pathway, which activates mammalian target of rapamycin (mTOR) in response to growth factors and also phosphorylates Beclin 1 |
| PMC3932427__F1 | Schematic showing the interference of Hepatitis C virus in the insulin signaling pathway |
| PMC3932693__F2 | Abiotic stress signalings and the related E3 ligases |
| PMC3932922__F1 | Cartoon presentation of LRRK2 showing multidomain structure |
| PMC3932947__F7 | En2 modulates IGF1's pleiotropic effects in GNPs, potentially through altered S6 kinase activation |
| PMC3932967__F2 | Role of Notch signaling in the mammalian heart |
| PMC3933272__F4 | WNT signaling pathway |
| PMC3933348__F1 | Overview of tamoxifen metabolism pathway and the main enzymes involved |
| PMC3934442__F5 | Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis |
| PMC3934462__F1 | Apoptosis signaling and cell death relevant drugs |
| PMC3934763__F7 | Insulin signaling KEGG pathway in adipose tissue |
| PMC3934763__F8 | PI3K-AKT signaling KEGG pathway in adipose tissue |
| PMC3934873__F1 | Iron Transport Machinery of Human Cells: Players and Their Interactions |
| PMC3934928__F2 | Cell biological view of Toll-like receptor function: regulation through compartmentalization |
| PMC3935308__F2 | High-confidence reaction map of the TSLP signaling pathway |
| PMC3935401__F2 | PR pathways in eukaryotes |
| PMC3935732__F4 | Role of ABL Family Kinases in Cancer: from Leukemia to Solid Tumors |
| PMC3935825__F1 | Accurate measurement of nicotinamide adenine dinucleotide (NAD+) with high-performance liquid chromatography |
| PMC3936121__F7 | MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family |
| PMC3936199__F3 | Iron homeostasis in the liver |
| PMC3936289__F4 | Major crosstalks between the PI3K and the MAPK cascades |
| PMC3936406__F1 | Molecular signaling pathways mediated by MET receptor tyrosine kinase in neurons |
| PMC3936609__F6 | Redox-Mediated and Ionizing-Radiation-Induced Inflammatory Mediators in Prostate Cancer Development and Treatment |
| PMC3936609__F7 | Redox-Mediated and Ionizing-Radiation-Induced Inflammatory Mediators in Prostate Cancer Development and Treatment |
| PMC3936743__F7 | Control of the concentration of transcripts for enzymes involved in central carbon metabolism |
| PMC3936782__F2 | Neuroprotective/apoptotic intracellular cascades at baseline and as mitigated by mood stabilizers in BD |
| PMC3936888__F7 | Scheme for illustrating the effect of Naproxen on the regulation of cell cycle and apoptosis mediated through the inhibition of the PI3-K signaling pathway |
| PMC3936891__F1 | Overview of the folate-methionine metabolic pathway investigated in this study |
| PMC3936936__F1 | Network of interactions between products of candidate genes from the QTL regions |
| PMC3937030__F1 | MTOR pathway signaling pathway |
| PMC3937033__F8 | T cell PPI Network mapped to TCR, with main JAK-STAT and MAPK signaling pathways |
| PMC3937043__F5 | Ingenuity Pathway Analysis (IPA) of the 39 differentially expressed genes in MFG transcriptome at 18 hpi vs |
| PMC3937046__F7 | Neuronal circuit diagram of the light input pathway in the tadpole retina |
| PMC3937154__F5 | IPA graphic representation of the network "Cell death and survival, DNA replication, recombination, and repair, cellular response to therapeutics". Nodes represent genes and lines show the relationship between genes |
| PMC3937510__F2 | Canonical Wnt signaling () |
| PMC3937760__F4 | miR-182 plays an important role in CEBPA/miR-122/IGF1R pathway |
| PMC3938021__S3 | Dissecting the Molecular Basis of the Role of the O-Mannosylation Pathway in Disease: α-Dystroglycan and Forms of Muscular Dystrophy. |
| PMC3938170__F1 | Folate pathway |
| PMC3938254__F7 | Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis |
| PMC3938256__F1 | Genetics of lymphatic anomalies |
| PMC3938550__F5 | Comparative Genomic and Transcriptomic Analyses of LNCaP and C4-2B Prostate Cancer Cell Lines |
| PMC3938851__F1 | Insulin/IGF-1 signaling and regulation |
| PMC3939313__F1 | Quantitative Lipid Metabolomic Changes in Alcoholic Micropigs with Fatty Liver Disease |
| PMC3939323__F3 | A, JAK-STAT signaling pathway in interaction network |
| PMC3939471__F1 | Involvement of CD81 in Hepatitis C Virus (HCV) lifecycle |
| PMC3940258__F5 | Paramyxovirus inhibition of IFN signaling pathways |
| PMC3940310__F2 | Pathways for hepatic fatty acid synthesis (FASN) |
| PMC3940310__F4 | Endogenous fatty acid metabolism in the control of hepatic gene transcription |
| PMC3940357__F1 | Frizzled homolog proteins, microRNAs and Wnt Signaling in Cancer |
| PMC3940872__F7 | Synthetic Alpha-Bromo-2',3,4,4'-Tetramethoxychalcone (Alpha-Br-TMC) Inhibits the JAK/STAT Signaling Pathway |
| PMC3940969__F1 | Cytokine signaling pathways in brain preconditioning |
| PMC3940969__F2 | TLR signaling pathways in cerebral IT |
| PMC3941008__F1 | Complement activation pathways |
| PMC3941025__F1 | MAVS filaments and activation of the IFN-I pathway |
| PMC3941170__F2 | Cell cycle regulation by p16Ink4b/p14ARF |
| PMC3941198__F1 | Milk lipid secretion: recent biomolecular aspects |
| PMC3941218__F1 | Insulin- and IGF-1-signaling pathways |
| PMC3941591__F4 | Top Ingenuity networks of genes whose expression was significantly altered in the hippocampus upon FST exposure |
| PMC3941591__F5 | 'Ephrin Receptor Signaling' was the second canonical IPA pathway induced in LR rats upon FST exposure |
| PMC3941921__F2 | Highest scoring upregulated network: Cellular Assembly |
| PMC3941921__F3 | Highest-scoring downregulated network: Energy Production, Metabolism and Cell Structure |
| PMC3941921__F5 | Downregulated network of CANB1 in traumatic brain injury (TBI) |
| PMC3942026__F2 | Evolution of a Cellular Immune Response in Drosophila: A Phenotypic and Genomic Comparative Analysis |
| PMC3942330__F3 | Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms |
| PMC3942330__F4 | Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms |
| PMC3942330__F5 | Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms |
| PMC3942330__F6 | Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms |
| PMC3942330__F8 | Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms |
| PMC3942504__F1 | Molecular mechanisms of Bcl-6 expression in T cells |
| PMC3942542__F1 | Cyclic adenosine diphosphate ribose mediated Ca2+signaling |
| PMC3942726__F1 | Simplified schematic diagram of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway and proposed cellular regulation of muscle protein synthesis in response to hypoxia, caloric restriction, insulin, muscle contraction, and leucine |
| PMC3942790__F2 | Hepcidin as therapy for primary and secondary iron overload disorders: pre-clinical models and approaches |
| PMC3942836__F1 | Schematic review |
| PMC3943178__F3 | Coordination of macrophage-mediated signaling and muscle regeneration |
| PMC3943226__F1 | Apoptosis signaling pathway |
| PMC3943304__F5 | Activation of growth factor receptor protein tyrosine kinases results in autophosphorylation on tyrosine residues |
| PMC3943304__F6 | Canonical and non-canonical JAK-STAT pathway and its subversion by BCR-ABL or mutant KIT |
| PMC3943494__F3 | Ceramide Metabolic Pathway in Epidermis |
| PMC3943598__F1 | Molecular mechanisms in Carney complex (CNC) and McCune-Albright syndrome (MAS): Receptor activation (ligand binding) makes GsA to exchange GDP to GTP, GsA is then freed from the BetaG dimer and activates adenyl cyclase (AC) |
| PMC3943605__F4 | GENETICS AND EPIGENETICS OF ADRENOCORTICAL TUMORS |
| PMC3943663__F1 | Dendritic cells in progression and pathology of HIV infection |
| PMC3943763__F1 | Toll-like receptors in antiviral innate immunity |
| PMC3943767__F3 | Proteolytic pathway that controls glucose uptake in fat and muscle |
| PMC3943797__F1 | Coagulation, Protease Activated Receptors and Viral Myocarditis |
| PMC3943799__F2 | Cytosolic DNA sensing pathways |
| PMC3943829__F1 | A scheme of metabolic pathway for cholesterol biogenesis |
| PMC3944192__F1 | Kidney Regeneration: Common Themes From the Embryo to the Adult |
| PMC3944211__F1 | Bone morphogenetic protein signaling in nephron progenitor cells |
| PMC3944232__F7 | Schematic illustration of LEF1/CYLD and cIAPs in the modulation of RIP1 deubiquitination and triggering of apoptosis via caspase-8 |
| PMC3944239__F8 | Working model |
| PMC3944254__F5 | Proposed model of hypoxia-induced cellular processes presumably leading to antifolate resistance |
| PMC3944264__F6 | Proposed model for miR-542-3p-mediated suppression of osteoblast proliferation and differentiation |
| PMC3944267__F8 | Proposed mechanism for the differential response of tenocytes to oxidative stress under different extracellular glucose concentrations |
| PMC3944322__F1 | Parkinson's Disease Gene Therapy: Success by Design Meets Failure by Efficacy |
| PMC3944655__F1 | Molecular mechanisms linking ROS, antioxidants, and the insulin signalling pathway |
| PMC3944813__F4 | Depletion of the NAD cofactor leads to suppression of metabolic flux over numerous essential NAD-dependent pathways |
| PMC3944819__F7 | Schematic of ANDV N and GnGc protein regulation of TBK1 signaling |
| PMC3944966__F1 | p-Hydroxyphenylpyruvate, an Intermediate of the Phe/Tyr Catabolism, Improves Mitochondrial Oxidative Metabolism under Stressing Conditions and Prolongs Survival in Rats Subjected to Profound Hemorrhagic Shock |
| PMC3945033__F2 | Computational simulation of eicosanoid profile in ATP-stimulated BMDM |
| PMC3945331__F4 | Modules identified by functional and gene expression enrichment analysis |
| PMC3945331__F5 | Additional functional modules identified by ingenuity pathway analysis |
| PMC3945521__F7 | TRIMmunity: The roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity |
| PMC3945866__F6 | In addition to the known pathways that activate hepcidin expression, we show that Ras/RAF-triggered signals and the mTOR pathway are involved in hepcidin suppression |
| PMC3946160__F4 | Glutamate, BDNF, insulin and glucagon-like peptide 1 (GLP-1) improve neuronal bioenergetics and protect the neurons against neurodegenerative disease and traumatic injury |
| PMC3946526__F6 | The Expression and Prognostic Significance of Retinoic Acid Metabolising Enzymes in Colorectal Cancer |
| PMC3946634__F1 | Tumor suppressive signatures of miR-200 |
| PMC3946676__F1 | Changing appetites: The adaptive advantages of fuel choice |
| PMC3946676__F2 | Changing appetites: The adaptive advantages of fuel choice |
| PMC3946772__F1 | Non Alcoholic Fatty Liver Disease, Hepatic Insulin Resistance and Type 2 Diabetes |
| PMC3946959__F1 | Proposed signaling pathway for PCB detoxification in vivo |
| PMC3947043__F1 | Molecular alterations and biomarkers in colorectal cancer |
| PMC3947125__F3 | Schematic model of the autophagy pathway demonstrates several relevant markers of autophagy which are potentially influenced by a high cholesterol diet as well as possible points of regulation try resveratrol (RV) |
| PMC3947295__F1 | Scheme of the metabolic pathway of n-6 and n-3 long-chain polyunsaturated fatty acids |
| PMC3947362__F7 | The proposed model for the signaling events in mature, human oligodendrocytes in response to B. burgdorferi |
| PMC3947380__F8 | Cellular response pathways of RPE cells upon AGE stimulation |
| PMC3947439__F1 | Molecular pathways regulated by PGE2 that are inhibited by aspirin |
| PMC3947622__F1 | Molecular programming of B cell memory |
| PMC3947657__F4 | H460 non-small cell lung cancer stem-like holoclones yield tumors with increased vascularity |
| PMC3947766__F1 | Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time |
| PMC3947785__F1 | What's the Mtrr with your grandparents? |
| PMC3948174__F1 | Regulation of G protein-mediated signaling by RGS2 in the heart |
| PMC3948775__F2 | Pathway Based Analysis of Genes and Interactions Influencing Porcine Testis Samples from Boars with Divergent Androstenone Content in Back Fat |
| PMC3948775__F9 | Pathway Based Analysis of Genes and Interactions Influencing Porcine Testis Samples from Boars with Divergent Androstenone Content in Back Fat |
| PMC3949135__F1 | Schematic Ig synthesis pathway |
| PMC3949417__F1 | Sensing of transferrin-bound iron and regulation of hepcidin expression in hepatocytes |
| PMC3949429__F2 | Two major signaling pathways activated by HBV and HCV in hepatocarcinogenesis |
| PMC3949576__F2 | Effective double whammy targets DNA synthesis in leukemia |
| PMC3950316__F8 | Schematic representation of A-SMase-driven Mitf pathway |
| PMC3950548__F2 | Representation of IL-33 pathway in T-helper cells |
| PMC3950678__F6 | Causal gene network inferred from top discriminative modules at a significance level of 0.005 |
| PMC3950821__F3 | Leveraging melanocortin pathways to treat glomerular diseases |
| PMC3951427__F12 | New miRNA Profiles Accurately Distinguish Renal Cell Carcinomas and Upper Tract Urothelial Carcinomas from the Normal Kidney. |
| PMC3951765__F1 | NLRP3 inflammasome activation: CD36 serves double duty |
| PMC3951797__F6 | Postsqualene cholesterol biosynthetic pathway |
| PMC3951797__F8 | CYP enzymes involved in the synthesis and degradation of vitamin D |
| PMC3951857__F1 | Wnt/Beta-catenin signaling pathway |
| PMC3952039__F1 | To Bud or not to Bud: The RET perspective in CAKUT |
| PMC3952073__F4 | TAK1 Regulates Hepatic Cell Survival and Carcinogenesis |
| PMC3952558__F2 | TLR4 Signaling Pathway |
| PMC3952878__F4 | FAK functions in cancer stem cells |
| PMC3953130__F2 | Ack1 signaling pathway in normal and cancerous cells |
| PMC3953345__F2 | Schematic presentation of the molecular mechanisms of myogenic differentiation |
| PMC3953715__F1 | PI3K/PTEN-mTOR pathway |
| PMC3953890__F1 | EGFR-axis pathway that contributes to cyst formation and progressive enlargement in ADPKD and ARPKD |
| PMC3953959__F6 | Regulation of TFs activity by degradation modulated by H2O2 |
| PMC3954160__F1 | Insulin signaling pathway |
| PMC3954580__F2 | MEK5 regulation and downstream targets |
| PMC3954580__F5 | MEK5/ERK5 Pathway: The first fifteen years. |
| PMC3954635__F4 | Beta-catenin pathway |
| PMC3954825__F2 | DISC1 as a key lead in studying cortical development and associated brain disorders |
| PMC3954954__F6 | Tissue Factor Inflammatory Response Regulated by Promoter Genotype and p38 MAPK in Neonatal vs. Adult Microvascular Endothelial Cells |
| PMC3955095__F2 | Targeting the Bcl-2 Family for Cancer Therapy |
| PMC3955168__F3 | The unfolded protein response (UPR) pathway and its chemical modulators |
| PMC3955735__F5 | Glucose and glutamine metabolism is altered by oncogenic K-Ras |
| PMC3956136__F1 | Canonical Wnt B catenin signaling pathway |
| PMC3956502__F4 | Mechanisms underlying the inhibition of interferon signaling by viruses |
| PMC3956512__F1 | The unfolded protein response (UPR) pathway in Cryptococcus |
| PMC3956533__F7 | Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells |
| PMC3956536__F5 | Heterogenic final cell cycle of chicken retinal Lim1 horizontal cells is not regulated by the DNA damage response pathway |
| PMC3956809__F4 | Tissue-specific expression within individual functions–a case of insulin signaling pathway |
| PMC3956974__F3 | Signaling control of CAR activation |
| PMC3957180__F1 | Scheme depicting interactions of the ET and NO pathway as described in this chapter |
| PMC3957735__F2 | Short-patch base excision repair pathway |
| PMC3957914__F5 | IFN-Beta-mediated regulation of PI3K/Akt/mTOR signaling and pharmacological agents active in this pathway |
| PMC3957919__F7 | Proposed model depicting the role of IFI35 in negative regulation of RIG-I signaling |
| PMC3958036__F9 | Schematic model of how SH2B1B enhances gene expression and neuronal differentiation through STAT3 (step 1) |
| PMC3958149__F2 | Example of Janus kinase (JAK) inhibitors blocking cytokine signalling |
| PMC3958334__F3 | Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila |
| PMC3958665__F6 | KEGG pathway for Huntington's disease (proteins identified in our study of the PBMC proteome are highlighted by red stars) |
| PMC3959159__F1 | Major components of the TGF-ß signaling pathway |
| PMC3959161__F2 | Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity |
| PMC395917__F5 | BMP4 and LIF signaling in pluripotency |
| PMC3959190__F3 | Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights |
| PMC3959213__F1 | Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway |
| PMC3959213__F10 | Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway |
| PMC3959213__F6 | Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway |
| PMC3959225__F5 | Pharmacogenomics of insulin-like growth factor-I generation during GH treatment in children with GH deficiency or Turner syndrome. |
| PMC3959571__F1 | Q6 biosynthesis in S |
| PMC3959597__F7 | Cross talk between metformin, androgens, and IGF system and molecular mechanisms of metformin inhibitory effects |
| PMC3959765__F3 | RANKL-perturbed network and master regulators |
| PMC3959773__F1 | Mitochondrial respiratory chain |
| PMC3960188__F1 | mTOR pathway in colorectal cancer: an update |
| PMC3960188__F2 | mTOR pathway in colorectal cancer: an update |
| PMC3960190__F1 | Perspectives of TGFB inhibition in pancreatic and hepatocellular carcinomas |
| PMC3960348__F1 | Schematic overview of the mTOR signaling pathway with the most important factors and their action |
| PMC3960348__F2 | Schematic overview of the mTOR signaling pathway with the target position of drugs |
| PMC3960371__F4 | Autophagy Paradox and Ceramide |
| PMC3960487__F2 | Signaling pathways involved in YPP regulation |
| PMC3960720__F8 | Q43L mutant of neuregulin 2B is a pan-ErbB receptor antagonist |
| PMC3960869__F2 | Interaction of Neisserial surface molecules with the complement system |
| PMC3961361__F8 | MAVS-MKK7-JNK2 Defines a Novel Apoptotic Signaling Pathway during Viral Infection |
| PMC3961481__F1 | Novel pathway links telomeres to NK-cell activity |
| PMC3961642__F8 | TXNIP deficiency disrupts mitochondrial fuel selection |
| PMC3961644__F8 | Proposed model for the negative or positive regulation of chondrocyte maturation or apoptosis by Smpd3/nSMase2, respectively |
| PMC3961774__F5 | Role of Heme Oxygenase-1 in Postnatal Differentiation of Stem Cells: A Possible Cross-Talk with MicroRNAs. |
| PMC3961774__F7 | Role of Heme Oxygenase-1 in Postnatal Differentiation of Stem Cells: A Possible Cross-Talk with MicroRNAs |
| PMC3961794__F1 | Mononuclear Phagocyte System in Homeostasis and Disease: A Role for Heme Oxygenase-1 |
| PMC3961794__F2 | Mononuclear Phagocyte System in Homeostasis and Disease: A Role for Heme Oxygenase-1 |
| PMC3961843__F1 | Selected glucose metabolic genes and their potential roles in tumor development |
| PMC3961947__F1 | Molecular pathways altered by green tea extract |
| PMC3962044__F1 | NFKB signaling pathways in osteoclast lineage cells |
| PMC3962044__F3 | IAP antagonists and NFKB signaling in osteoclast lineage cells |
| PMC3962112__F1 | Biosensor-derived promoters upstream of modules B and C to control the expression of fadD and atfA, and the ethanol biosynthetic pathway (adhB and pdc), respectively |
| PMC3962149__F1 | Main metabolic pathways of E.coli together with transcription factors |
| PMC3962153__F2 | Products for which C |
| PMC3962195__F1 | Biological processes and genes implicated in the Parkinson's disease |
| PMC3962345__F4 | Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5-/- Mice |
| PMC3962547__F14 | Integration of metabolic control, cell growth and proliferation, and their regulation by phosphoinositides |
| PMC3962548__F4 | Controlling clot formation |
| PMC3962777__F2 | NEW STRATEGIES FOR TRIPLE NEGATIVE BREAST CANCER - DECIPHERING THE HETEROGENEITY |
| PMC3962840__F5 | Relationships between the cellular signal pathways in HAdV-36 infected human muscle cells |
| PMC3963078__F7 | HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors |
| PMC3964016__F1 | Cl- channels and proposed functions in vascular smooth muscle cells |
| PMC3964053__F4 | BMP signaling in germ cells across the Metazoa |
| PMC3964483__F1 | Outside the Box Signaling: Secreted Factors Modulate GnRH Receptor-Mediated Gonadotropin Regulation |
| PMC3964949__F3 | Motif-mediated interactions annotated in the ELM resource mapped onto the KEGG () human Phosphatidylinositol-3'-kinase-(PI3K)-Akt signaling pathway (hsa04151) |
| PMC3964957__F6 | Pathway diagram customization is available via the web interface, and lets the user control many aspects of the pathway diagram |
| PMC3965010__F1 | Example of disease curation and visualization in Reactome |
| PMC3965173__F1 | Signaling pathways that can be inhibited to increase the radiation response of tumors |
| PMC3965177__F3 | Egr-1: new conductor for the tissue repair orchestra directs harmony (regeneration) or cacophony (fibrosis) |
| PMC3965205__F1 | Hypothetical mechanisms of tolerance within the TLR4 pathway |
| PMC3965270__F8 | Integration of L-R Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2 |
| PMC3965409__F6 | Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway |
| PMC3965671__F4 | Immunopathogenesis of inflammatory bowel disease (IBD) |
| PMC3965671__F5 | The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs and Skin. |
| PMC3965671__F6 | Mechanisms by which Th17 and Th22 pathways contribute to psoriasis and atopic dermatitis |
| PMC3966314__F3 | Impact of miR-215 on cell proliferation, cell cycle, chemoresistance and EMT |
| PMC3966557__F1 | RGS proteins in the regulation of GPCR, PTH, and Wnt signaling pathways during bone remodeling |
| PMC3966620__F1 | Cl- channels in cardiac myocytes |
| PMC3966702__F7 | ABCA1 expression and function can be induced by GPR119 to protect from atherosclerosis |
| PMC3966871__F3 | High-Throughput Quantitative Proteomic Analysis of Dengue Virus Type 2 Infected A549 Cells |
| PMC3967109__F2 | Target gene set within Alzheimer's disease environmental network |
| PMC3967167__F1 | Schematic drawing of the PI3K/Akt signaling pathway |
| PMC3967171__F2 | Sex hormones and SREBP selectively regulate expression of Aldh1 |
| PMC3967813__F2 | IFNAlpha-2b signaling via JAK-STAT pathway, adapted from [] |
| PMC3967838__F1 | DNA2 Resolves Expanding Flap in Mitochondrial Base Excision Repair |
| PMC3967868__F1 | Drug resistance mediated by AEG-1/MTDH/LYRIC |
| PMC3968382__F1 | New anti-complement drugs: not so far away |
| PMC3968564__F1 | 1A: Base excision repair (BER) pathway targets DNA damaged during replication or by environmental agents |
| PMC3969038__F1 | NFKB signaling pathway and cancer related mutations |
| PMC3969039__F2 | Putative model of the mechanism of vascular homeostasis mediated by apelin-APJ signaling |
| PMC3969300__F1 | Establishment of left/right (LR) asymmetry during development |
| PMC3969565__F1 | Emergence and Evolutionary Analysis of the Human DDR Network: Implications in Comparative Genomics and Downstream Analyses |
| PMC3969740__F2 | A) Pathogen recognition receptors RIG-I and TLR3 detect HCV ds RNA and activate via their adaptor molecules IPS-1 and TRIF |
| PMC3969788__F4 | Strategies for Delivery of Therapeutics into the Central Nervous System for Treatment of Lysosomal Storage Disorders |
| PMC3969803__F2 | Summary of key changes in cancer metabolic reprogramming |
| PMC3969803__F3 | Summary of the mechanism of several important drug candidates for anti-cancer metabolism therapies |
| PMC3969850__F7 | Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness |
| PMC3969997__F7 | The hypothetical signaling pathway in pathological angiogenesis regulated by interactions of activated VEGFR2 and EPOR |
| PMC3970144__F6 | HCV assembly involves a concerted action of all viral proteins and hijacks the host lipoprotein synthesis pathway |
| PMC3970201__F2 | Self-consumption: the interplay of autophagy and apoptosis |
| PMC3970295__F4 | Wnt signaling as a pathway to increase bone formation |
| PMC3970352__F1 | Metabolic pathway of Cytokines in humans |
| PMC3970352__F2 | Metabolic pathway of Inflammatory Response in humans |
| PMC3970768__F1 | The biotin cycle and the known and putative roles |
| PMC3970924__F2 | Molecular pathology of FLS in RA |
| PMC3970925__F1 | Activation of PPRs in cardiomyocytes by DAMPs during myocardial I/R injury |
| PMC3971994__F1 | HGF/Met receptor signaling pathway |
| PMC3972113__F13 | Overexpression of miR-125a in Myelodysplastic Syndrome CD34+ Cells Modulates NFKB Activation and Enhances Erythroid Differentiation Arrest |
| PMC3972651__F2 | Schematic diagram of the transport pathways during acrosome formation |
| PMC3972652__F1 | Biosynthesis pathway for gangliosides |
| PMC3972679__F1 | The two pathways of apoptosis |
| PMC3972679__F2 | Apoptotic pathways induced in beta cells in type 2 diabetes |
| PMC3972890__F6 | CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis |
| PMC3973006__F8 | Schematic model of TGFB signaling pathways for CRP2 induction in VSMCs |
| PMC3973103__F1 | Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch |
| PMC3973207__F8 | Schematic diagram showing differences in the thyroid cancer cell lines sensitive or resistant to apoptosis |
| PMC3973216__F4 | Simplified representation of the regulation of actin cytoskeleton pathway and differentially regulated genes |
| PMC3973244__F7 | Role of RNase L and TLR3 activation during inflammation in insulin response of obese people's myotubes |
| PMC3973444__F7 | Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders |
| PMC3973632__F5 | Integrated Analysis of Copy Number Variation and Genome-Wide Expression Profiling in Colorectal Cancer Tissues |
| PMC3973656__F1 | Curbing autophagy and histone deacetylases to kill cancer cells |
| PMC3973904__F1 | Cholesterol metabolism, lipid rafts and autism spectrum disorders |
| PMC3974425__F5 | Ezrin expression and cell survival regulation in colorectal cancer |
| PMC3974512__F1 | Hepatitis C virus entry into hepatocytes |
| PMC3974514__F1 | Metabolic pathway of azathioprine/mercaptopurine metabolism |
| PMC3974768__F8 | Stem and Progenitor Cell Subsets Are Affected by JAK2 Signaling and Can Be Monitored by Flow Cytometry |
| PMC3974825__F1 | Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer |
| PMC3974856__F2 | Tolerogenic plasmacytoid DC |
| PMC3974979__F8 | Working model of critical role for GDF-15 in NE-induced myocardial hypertrophy |
| PMC3974997__F2 | Interference with the host NFKB signaling pathways by STPKs of pathogenic bacteria: LegK1, OspG, and NleH1 |
| PMC3975104__F2 | A simplified model of some of the signaling pathways leading to LTD of the pf-PC synapse |
| PMC3975365__F1 | Apoptosis induction and signaling |
| PMC3975365__F2 | Tumor's interaction with its solid microenvironment |
| PMC3975365__F3 | So-called PI3-K/Akt/mTOR survival pathway |
| PMC3975402__F2 | Apoptosis pathway |
| PMC3975429__F1 | MAPK signalling cascades leading to MK5 activation |
| PMC3975838__F1 | Janus kinase 2 (JAK2)/signal transducer and activation of transcription (STAT) and hedgehog (Hh) signaling pathways in normal development (A) and mechanisms of Hh signaling in cancer (B) |
| PMC3975884__F1 | EGFR associated signaling pathways in lung cancer |
| PMC3976145__F1 | Genes involved in the WNT signaling pathway |
| PMC3976256__F9 | Mycobacterium bovis BCG Triggered MyD88 Induces miR-124 Feedback Negatively Regulates Immune Response in Alveolar Epithelial Cells |
| PMC3976587__F7 | Post-Transcriptional Regulation of Cytokine Signaling by AU-Rich and GU-Rich Elements |
| PMC3976613__F2 | Non-selective autophagy regulation during diabetic nephropathy (DN) |
| PMC3976614__F1 | Modulation of mitochondrial dysfunction by the PINK1/PARKIN pathway |
| PMC3976626__F8 | By simultaneously inhibiting CBS activity and inhibiting GOT1, a key enzyme of the malate/aspartate shuttle, AOAA acts as an inducer of 'synthetic lethality' in cancer cells |
| PMC3976810__F2 | Molecular pathways are altered due to modulation of signaling pathway in skin cancer |
| PMC3976829__F4 | Schematic illustrations for potential signaling pathway of IMF deposition in skeletal muscles regulated by GHR and SOCS3 |
| PMC3976840__F2 | FASN related metabolic and signal transduction pathways |
| PMC3976861__F2 | Representation of the p53 signaling pathway map from KEGG |
| PMC3977149__F1 | p53 effects multiple areas of cellular metabolism |
| PMC3977151__F1 | GOLGI IN COPPER HOMEOSTASIS: A VIEW FROM THE MEMBRANE TRAFFICKING FIELD |
| PMC3977192__F8 | LTP pathway components and interacting proteins: response in hippocampus |
| PMC3977653__F1 | At Loose Ends: Resecting a Double-Strand Break |
| PMC3977809__F2 | EGAN analysis showing all the differentially expressed enriched pathway genes |
| PMC3977821__F6 | Robustness and Plasticity of Metabolic Pathway Flux among Uropathogenic Isolates of Pseudomonas aeruginosa |
| PMC3977891__F2 | Interplay between Wnt signaling and other anti-ageing pathways |
| PMC3977945__F1 | Simplified Wnt/Beta-catenin pathway |
| PMC3977945__F2 | Simplified phosphorylation-mediated regulation of the core Wnt/Beta-catenin pathway components |
| PMC3977945__F3 | Ubiquitination-mediated regulation of the core Wnt/Beta-catenin pathway components |
| PMC3978192__F2 | Pathophysiology and pharmacology of hepcidin |
| PMC3978385__F3 | NRAS mutant melanoma: biological behavior and future strategies for therapeutic management |
| PMC3978476__F4 | Major metabolites and genes contributing to the choline metabolism pathway |
| PMC3978512__F3 | Canonical WNT/Beta-catenin signaling genes marked in green are hypermethylated in parous women (suggesting down-regulation of the gene in parous women) |
| PMC3978517__F2 | The replication checkpoint pathway activated following DNA damage |
| PMC3978568__F1 | Schematic representation and overview of PTEN/PI3K/AKT signaling and a model of the mechanism of peroxisome proliferator-activated receptor (PPAR) action |
| PMC3978582__F3 | Functional gene networks identified using Ingenuity Pathway Analysis (IPA) from differentially expressed genes between the control and treated discs |
| PMC3978582__F4 | Functional gene networks identified using Ingenuity Pathway Analysis (IPA) from differentially expressed genes between the control and treated discs |
| PMC3978582__F5 | Functional gene networks identified using Ingenuity Pathway Analysis (IPA) from differentially expressed genes between the control and experimental discs |
| PMC3978635__F1 | mTOR pathway and actions |
| PMC3978635__F2 | mTOR-dependent pathways and inhibitors |
| PMC3978640__F6 | Blocking the transforming growth factor B (TGFB) signalling pathway |
| PMC3978875__F6 | Proposed signalling interactions between C-type natriuretic peptide (CNP) and mechanical loading in chondrocytes |
| PMC3979117__F1 | Schematic illustration summarizing apoptotic signaling through the death receptor pathway and the mitochondrial pathway |
| PMC3979327__F3 | MicroRNA networks regulate development of brown adipocytes |
| PMC3979452__F4 | MiRNA regulation of skin fibrosis in epithelial and fibroblast cells |
| PMC3979678__F3 | Global Changes in Gene Expression of Barrett's Esophagus Compared to Normal Squamous Esophagus and Gastric Cardia Tissues |
| PMC3979852__F8 | Chemokine Receptor CCR8 Is Required for Lipopolysaccharide-Triggered Cytokine Production in Mouse Peritoneal Macrophages |
| PMC3980079__F1 | Heart Failure and Loss of Metabolic Control |
| PMC3980263__F3 | The LNG1 data set |
| PMC3980586__F1 | Molecular Pathways: Emerging Roles of Mammalian Sirtuin SIRT7 in Cancer |
| PMC3980610__F1 | LIF/JAK/STAT3-mediated growth inhibitory signaling in medullary thyroid cancer |
| PMC3980725__F1 | PI3K pathway inhibitors for the treatment of brain metastases with a focus on HER2+ breast cancer |
| PMC3980740__F5 | Signaling circuit driving transformation and tumorigenesis |
| PMC3980848__F1 | MicroRNA Regulation of T Helper Cell Differentiation and Plasticity |
| PMC3980848__F3 | MicroRNA Regulation of T Helper Cell Differentiation and Plasticity |
| PMC3980897__F1 | Dual-view setup of the enRoute visualization technique |
| PMC3980962__F1 | Origins and implications of pluripotent stem cell variability and heterogeneity |
| PMC3981547__F3 | Structures of human IL-6/IL-6RA/gp130 hexameric complex (a), mouse LIFR in complex with human LIF (b), and human CNTF/CNTFRA/LIFR/gp130 (c) assembled from known crystallographic, biochemical, and electron microscopic data |
| PMC3981572__F9 | Integrative model of the physiogenomic adaptations in adipose and liver tissue induced by energy overfeeding during the last 45 days of pregnancy |
| PMC3981821__F4 | Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C Virus |
| PMC3981821__F6 | Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C Virus |
| PMC3982103__F1 | Astrocytic-Neuronal-Astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA. |
| PMC3982149__F6 | Antibody against CD44s Inhibits Pancreatic Tumor Initiation and Post-Radiation Recurrence in Mice |
| PMC3982454__F8 | CD44 protein-protein interaction pathways were performed by String 9.0 Web software |
| PMC3982501__F4 | Receptor tyrosine kinase (RTK) signaling pathway is frequently hit by lentiviral vector (LV) integration |
| PMC3982775__F1 | Structure of the systems model of type C4 photosynthesis |
| PMC3982803__F1 | Insulin signaling pathways that control gluconeogenesis |
| PMC3982918__F1 | Notch signaling pathway and agents in clinical development |
| PMC3983064__F9 | Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation |
| PMC3983080__F1 | Multiple Model-Informed Open-Loop Control of Uncertain Intracellular Signaling Dynamics |
| PMC3983226__F1 | Predicting Kinase Activity in Angiotensin Receptor Phosphoproteomes Based on Sequence-Motifs and Interactions |
| PMC3983408__F7 | Mechanism of immune dysfunction in Huntington's disease |
| PMC3983448__F2 | Molecular pathway for microsatellite instability+ gastric cancer |
| PMC3983448__F4 | Human epidermal growth receptor family members, the PI3K/Akt pathway, and targeted drugs |
| PMC3983488__F1 | Matricellular TSP1 via CD47 restricts NO-sGC-cGMP signaling |
| PMC3983496__F2 | The proposed intracellular signaling pathways regulated by Cx43 hemichannels in bone cells |
| PMC3983565__F4 | MAPK signalling cooperates with loss of APC to promote adenoma development |
| PMC3983570__F3 | Tau Acts as a Mediator for Alzheimer's Disease-Related Synaptic Deficits |
| PMC3983582__F2 | Nucleotide excision repair (NER): the proteins associated with human diseases are highlighted |
| PMC3983720__F8 | Diagram of putative mDA differentiation pathway based on this and other studies |
| PMC3983859__F6 | Schematic representation of the RvD1 contribution to microglia alternative activation |
| PMC3983869__F1 | Beta-Catenin is a multifunctional protein that localizes at cell-cell contacts, the nucleus, cytosol and centrosomes |
| PMC3984536__F3 | HCV life cycle and points of intervention |
| PMC3984540__F6 | S1P induced changes in epithelial ovarian cancer proteolysis, invasion, and attachment care mediated by Gi and Rac |
| PMC3984774__F4 | RB/E2F pathway |
| PMC3984876__F1 | Cilia in the nervous system: linking cilia function and neurodevelopmental disorders |
| PMC3985001__F1 | The CNS-immune system crosstalk |
| PMC3985661__F8 | Schematic representation of PARP1-TDP1 coupling for the repair of Top1-DNA covalent complexes |
| PMC3985673__F5 | Immune activation-related modules differentially correlated in NSCLC |
| PMC3986091__F3 | Pathophysiology of Lung Injury Induced by Common Bile Duct Ligation in Mice |
| PMC3986510__F1 | Ceramide de novo synthesis pathway |
| PMC3986510__F4 | Diagram demonstrating sites of interference by various small molecule agents or genetic ablation of enzymes engaged in ceramide and sphingolipid synthesis pathway |
| PMC3986533__F13 | Anabolic reaction sequences in chloroplasts (A,B) and root plastids (C,D) of wild-type (A,C) and cue1 mutant plants (B,D) |
| PMC3986565__F1 | Molecular pathways leading to cross-presentation in DCs |
| PMC3986808__F2 | Copper is passed (green arrows) to cuproproteins (dark green circles), including metallothioneins Crs5 and Cup1, in for example Saccharomyces cerevisiae, by copper metallochaperones (pale green circles, or ovals if membrane associated) |
| PMC3986830__F1 | DREAM complex: Master coordinator of cell cycle dependent gene expression |
| PMC3987972__F3 | Intracellular signalling pathways mediated by HLA class I or II antibody binding to endothelial cells |
| PMC3988238__F1 | Dendritic cells initiate T cell immunity in the lymph nodes |
| PMC3988467__F1 | Amino acid signalling upstream of mTOR |
| PMC3988522__F3 | BR biosynthetic pathway and the enzymes involved in each reaction |
| PMC3988951__F6 | Insights into TREM2-related signaling using data-driven network constructions and information provided by Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis |
| PMC3988961__F3 | Pathway analysis |
| PMC3989450__F2 | Canonical Wnt signalling |
| PMC3989450__F3 | Wnt-dependent interactions between cardiac myocytes and cardiac fibroblasts after acute myocardial infarction |
| PMC3989546__F1 | Molecular Pathways: Interleukin-15 Signaling in Health and in Cancer |
| PMC3989634__F2 | Myeloid differentiation primary-response protein 88 (MyD88)-dependent and MyD88-independent TLR-4 signaling pathway |
| PMC3989668__F2 | Ubiquitin-proteasome system maintains the balance between quiescence, self-renewal, and differentiation of HSCs.(A) The E3 ligases Itch, SCFFbxw7,CBL and SCFSkp2 maintain the quiescence of the HSC by targeting Notch, c-Myc, and STAT5, among others |
| PMC3989668__F3 | Ubiquitylation maintains the equilibrium between differentiation and transformation in adult stem cells |
| PMC3989729__F7 | A schematic diagram illustrating the interplay between TLX and the BMP-SMAD signaling pathway in the regulation of neurogenesis and astrogenesis |
| PMC3989738__F6 | Direct target genes of hypoxia-mediated hypoxia-inducible factor-1A (HIF-1A) signaling |
| PMC3989838__F1 | Insulin effects on endothelial cells |
| PMC3989895__F2 | Simplified pathway map of CCN1 and CCN2-dependent outside-in signaling pathways regulating endothelial cell function and behavior |
| PMC3989954__F1 | Crosstalk between mechanistic target of rapamycin signaling pathway and colorectal oncogenic pathways |
| PMC3989988__F1 | De novo serine biosynthesis diverges from glycolysis |
| PMC3990718__F9 | Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis |
| PMC3990910__F1 | Mammal Notch receptors, ligands, and canonical activation pathway |
| PMC3990910__F3 | Mechanisms of Notch signaling silencing in AML |
| PMC3991209__F1 | Diagram showing activation of Notch signalling |
| PMC3991464__F1 | Four pathways of androgen metabolism |
| PMC3991635__F4 | Microarray Analysis of Cell Cycle Gene Expression in Adult Human Corneal Endothelial Cells |
| PMC3991635__F6 | Microarray Analysis of Cell Cycle Gene Expression in Adult Human Corneal Endothelial Cells |
| PMC3991963__F1 | TGFB2 and Bone Morphogenetic Proteins in the Trabecular Meshwork and Glaucoma |
| PMC3991965__F2 | Prostaglandin Analogues on Aqueous Humor Outflow Pathways |
| PMC3992201__F2 | Genes identified in GWAS of Phase 1+2 AA subjects using a case-control model in the canonical pathway "calcium signaling." The gene or gene families with a significant association result are shown in orange |
| PMC3992244__F2 | Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer |
| PMC3992244__F3 | Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer |
| PMC3992320__F2 | Canonical BMP signaling pathway |
| PMC3992631__F3 | Comparison of gene expression in immobilized relative to planktonic yeast: (A) intermediary metabolism and (B) cell cycle |
| PMC3992846__F2 | Production of biosynthetic precursors during glycolytic metabolism and their putative regulation during Xenopus tail appendage regeneration |
| PMC3993104__F2 | Interplay between host and bacterial factors leads to tissue destruction, vascular leakage, and hyperinflammation in invasive GAS disease |
| PMC3993563__F8 | A model for how MARCH6 affects the cholesterol synthesis pathway |
| PMC3993568__F10 | PI3K/Akt1 pathway is a downstream effector of Jak2/Stat5 signaling in luminal mammary epithelial cells |
| PMC3993959__F3 | Bioinformatic analyses expose alterations in nucleic acid binding and regulatory proteins |
| PMC3994321__F1 | Autophagic pathways in mammalian cells |
| PMC3994404__F2 | KIT signaling pathways |
| PMC3994501__F9 | Signaling pathways for LTM formation upon associative olfactory conditioning of honeybees |
| PMC3994550__F1 | Insulin signaling pathway |
| PMC3994729__F4 | Expressional regulation of genes linked to immunity & programmed development in human early placental villi. |
| PMC3994912__F2 | Can Transcriptomics Provide Insight into the Chemopreventive Mechanisms of Complex Mixtures of Phytochemicals in Humans? |
| PMC3994981__F1 | PI3K and Cancer: Lessons, Challenges and Opportunities |
| PMC3994981__F2 | PI3K and Cancer: Lessons, Challenges and Opportunities |
| PMC3995050__F1 | The PI3K/Akt/mTOR pathway |
| PMC3995058__F4 | Mechanism of rejection of MHCIINEG myeloma cells by Id-specific CD4+ T cells |
| PMC3995081__F1 | The HOG and mating MAPK pathways in S |
| PMC3995130__F2 | mTOR Signaling in Cardiac Physiology and Disease |
| PMC3995293__F5 | Oxidative Stress-Associated Protein Tyrosine Kinases and Phosphatases in Fanconi Anemia |
| PMC3995458__F1 | Biosynthetic pathways of glycerophospholipids |
| PMC3995556__F9 | BTC-stimulated IL-8 production and bio-behaviors of lung cancer cells |
| PMC3995778__F4 | Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies |
| PMC3995778__F5 | Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies |
| PMC3995826__F2 | Pathways for (A) Maturity Onset Diabetes of the Young (hsa04950), (B) type 2 diabetes (hsa04930), and (C) Notch signaling pathway (hsa04330); adapted from Kanehisa, et al [] |
| PMC3995856__F4 | Pathway analysis and molecular interactions of focus genes AKT, CTNNB1, GAB2, and SERPINE1 (hightlighted in pink) |
| PMC3996160__F6 | A hypothetical model depicting the mechanisms used by SARS-CoV PLpro-TM to disrupt the STING-TRAF3-TBK1 complex required for activation of the IFNB production pathway |
| PMC3996455__F1 | Treg functional stability and its responsiveness to the microenvironment |
| PMC3996470__F1 | Receptor-mediated endocytic pathway in nonpolarized mammalian cells |
| PMC3996583__F2 | Construction of the FB-iPSC-CM regulatory circuit |
| PMC3996587__F1 | Extended model for the cyclin/Cdk network driving the mammalian cell cycle |
| PMC3996671__F1 | Ras and autophagy in cancer development and therapy |
| PMC3996849__F3 | Intestinal cholesterol absorption is a multistep process regulated by multiple genes |
| PMC3996895__F1 | Biogenesis of canonical and mirtron miRNAs in animal cells |
| PMC3996895__F2 | Canonical NFKB signaling network regulated by miRNAs |
| PMC3997009__F1 | Routes of presentation of viral peptides on DCs |
| PMC3997115__F1 | Caspase activation by the extrinsic (Fas-mediated) apoptosis pathway (left) vs |
| PMC3997659__F1 | Role of Ub and SUMO modification of PCNA |
| PMC3997674__F1 | Dual opposing signaling pathways of TRAIL |
| PMC3997674__F2 | Signaling pathway of TRAIL/drug combinations |
| PMC3997957__F1 | Cell cycle arrest by CDKN2A |
| PMC3998024__F2 | Top-ranked gene network |
| PMC3998120__F4 | Origins of Metastatic Traits. |
| PMC3998185__F7 | Metastatic Stem Cells: Sources, Niches, and Vital Pathways |
| PMC3998523__F1 | Sphingolipid pathway and subcellular localization of sphingolipid enzymes |
| PMC3998676__F1 | ADVANCING AGE IS ASSOCIATED WITH GENE EXPRESSION CHANGES RESEMBLING mTOR INHIBITION: EVIDENCE FROM TWO HUMAN POPULATIONS |
| PMC3998825__F1 | Alternatively Activated Macrophages Revisited: New Insights into the Regulation of Immunity, Inflammation and Metabolic Function following Parasite Infection |
| PMC3998839__F1 | mTORC1 is a component of mTOR that is directly inhibited by rapamycin and rapamycin derivatives like everolimus |
| PMC3998841__F2 | Inflammatory cytokine-associated idiosyncratic drug hepatotoxicity as a "network toxicity" |
| PMC3999155__F6 | HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1 |
| PMC3999169__F1 | Roles for TNF-Receptor Associated Factor 3 (TRAF3) in Lymphocyte Functions |
| PMC3999173__F2 | Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells |
| PMC3999200__F8 | Neuroprotective Effect of Hydrogen-Rich Saline against Neurologic Damage and Apoptosis in Early Brain Injury following Subarachnoid Hemorrhage: Possible Role of the Akt/GSK3B Signaling Pathway |
| PMC3999257__F4 | NRG1 signalling and neurite formation mediators |
| PMC3999750__F4 | PAR1 and PAR2 modulate TLR3-dependent expression of IFNB in CFs |
| PMC3999940__F3 | Case study of the RegPhos-discovered phosphorylation networks involved in BCR signaling pathway |
| PMC4000109__F2 | TGFB signalling cascade alterations that lead to prostate cancer |
| PMC4000238__F1 | Wnt pathway and its interactions with other pathways in bone |
| PMC4000238__F2 | The canonical Wnt, Ihh, Bmp and PTH/PTHrP signaling pathways in regulating the differentiation of mesenchymal precursors |
| PMC4000313__F2 | Death receptor signaling and programmed necrosis |
| PMC4000463__F1 | JAK2 receptor signaling and activation of STAT pathway |
| PMC4000654__F1 | Physiological and physiopathological UPR activated pathways in B cells |
| PMC4000931__F2 | Summary of the miRNAs and the TGFB pathway involved in HSCs |
| PMC4000931__F3 | Summary of the miRNAs and the VEGF pathway involved in HSCs |
| PMC4001025__F1 | Vpr induces G2/M arrest through activation of the SLX4 complex |
| PMC4001041__F1 | Schematic illustrating NLR attenuation of canonical and non-canonical NFKB signaling |
| PMC4001054__F1 | Proposed schematic models for the role of different lncRNAs (green) in neural development |
| PMC4001055__F2 | Spermatogenesis ROS endocrine gene transcriptional regulation |
| PMC4001295__F7 | Opposing TNFA/IL-1Beta- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation |
| PMC4001311__F6 | Schematics of the regulation of the HMOX1 expression under normal (a and b) and stress conditions (c and d) and without (a and c) or with (b and d) BRD4 knockdown |
| PMC4001324__F1 | Simplified overview of the receptor tyrosine kinase (RTK)-RAS and RAS-related RHEB signaling pathways |
| PMC4001531__F4 | Melanoma NOS1 expression promotes dysfunctional IFN signaling |
| PMC4001725__F2 | Estrogenic Steroid Hormones in Lung Cancer |
| PMC4001781__F3 | Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma |
| PMC4001841__F1 | PI3K-AKT pathway and associated cellular activities |
| PMC4001935__F7 | FoxD3 regulates cranial neural crest EMT via downregulation of Tetraspanin18 independent of its functions during neural crest formation |
| PMC4002088__F7 | Schematic representation of the proposed novel TXNIP/miR-124a/FOXA2/IAPP signaling pathway |
| PMC4002322__F1 | AMPK-p53-mTOR pathway in metabolic adaptation |
| PMC4002322__F2 | p53 regulation of energy metabolism |
| PMC4002662__F1 | Chemoprevention of Head and Neck Squamous Cell Carcinoma through Inhibition of NFKB Signaling |
| PMC4002662__F2 | Chemoprevention of Head and Neck Squamous Cell Carcinoma through Inhibition of NFKB Signaling |
| PMC4002809__F2 | Current model for NFKB signaling pathway induced by C-type lectin receptors |
| PMC4002811__F2 | Peli1 mediates IKK activation by the TRIF-dependent TLR pathway |
| PMC4002842__F2 | Network analysis of expression profiles of 10 µmol/L AA in HK-2 cells |
| PMC4002915__F2 | Signal pathways of IL-17 |
| PMC4002948__F7 | Possible molecular mechanisms by which Alpha-TOS overcomes the resistance of erbB2-expressing cells to apoptosis and sensitizes them to hrTRAIL-induced apoptosis |
| PMC4003231__F1 | Immune pathogenesis of gastric mucosa damage in H |
| PMC4003375__F1 | Nck proteins as the newly identified adaptors between the BCR complex and BCAP/PI3K/Akt pathway |
| PMC4003416__F2 | Targets of Twist proteins in the DNA damage response pathway |
| PMC4003867__F1 | Emerging role of Interleukin-22 in autoimmune diseases |
| PMC4003878__F2 | GSK3B and the control of infectious bacterial diseases |
| PMC400410__F3 | Functional associations of genes selected as differentially expressed in patients with juvenile rheumatoid arthritis (JRA) and normal controls |
| PMC400410__F4 | Functional associations of hypervariable (HV) genes in patients with juvenile rheumatoid arthritis (JRA) |
| PMC400410__F5 | Functional associations of genes identified by discriminant function analysis (DFA) in patients with juvenile rheumatoid arthritis (JRA) who were undergoing treatment |
| PMC4005015__F8 | DIETARY HYPERGLYCEMIA, GLYCEMIC INDEX AND METABOLIC RETINAL DISEASES |
| PMC4005015__F9a | DIETARY HYPERGLYCEMIA, GLYCEMIC INDEX AND METABOLIC RETINAL DISEASES |
| PMC4005337__F1 | Targeting angiogenesis for the treatment of prostate cancer. |
| PMC4005353__F1 | AGS genes cooperate to metabolize reverse transcription products of endogenous retroelements |
| PMC4005386__F2 | Signaling networks for brain, lung, and bone metastases of breast cancer |
| PMC4005604__F2 | Targeting the Mevalonate Cascade as a New Therapeutic Approach in Heart Disease, Cancer and Pulmonary Disease |
| PMC4005613__F1 | Molecular Pathways: Co-Expression of Immune Checkpoint Molecules: Signaling Pathways and Implications for Cancer Immunotherapy |
| PMC4005972__F4 | Proteins involved in the BCR signaling pathways |
| PMC4006928__F1 | DNA Damage Response, Redox Status and Hematopoiesis |
| PMC4007103__F2 | Biogenesis of Drosophila small regulatory RNAs |
| PMC4007119__F6 | ZZ primary bronchial epithelial cells show an enhanced inflammatory response dependent of the ERK/EGFR/ADAM17 pathway |
| PMC4007207__F9 | Model of the role of an epidermal barrier defect in tumour protection |
| PMC4007467__F11 | Proposed integrin signaling switch model |
| PMC4007596__F2 | Cytoscape plugin was used to analyze within Balb/c up-regulated genes, genes interaction within the same pathway and across different pathways |
| PMC4007596__F3 | Cytoscape plugin was used to analyse within C57Bl/6 up-regulated genes, genes interaction within the same pathway and across different pathways |
| PMC4007761__F2 | Secretory pathway components studied in zebrafish and implicated in human diseases |
| PMC4007780__F1 | CADBIOM model for the canonical TGFB pathway |
| PMC4007928__F1 | Key features of the phosphoinositide 3-kinase (PI3K) signaling pathway |
| PMC4007997__F4 | Molecular pathway analysis of regulated membrane protein changes in RLSCs as they undergo hepatocytic differentiation |
| PMC4007997__F5 | Upstream regulator analysis of membrane protein changes in differently regulated proteins involved in cell-to-cell signaling and interaction |
| PMC4008004__F1 | Hyperglycemia alters the expression of multiple genes of the transforming growth factor-B (TGF-B) pathway through the polyol pathway in retinal vessels |
| PMC4008226__F8 | A mechanism for integrated regulation of motility and adhesion in T cells and its role for transendothelial migration |
| PMC4008360__F3 | Ingenuity pathway network analysis of differentially expressed miRNAs |
| PMC4008387__F2 | Molecular mechanisms of hepcidin regulation |
| PMC4008642__F1 | Molecular Pathways: BRAF Induces Bioenergetic Adaptation by Attenuating Oxidative Phosphorylation |
| PMC4008712__F1 | Increases in Insulin Sensitivity among Obese Youth are Associated with Gene Expression Changes in Whole Blood |
| PMC4009339__F3 | Gene network of T-ALL (early response) derived from GeneMANIA (a) and STRING (b) (NR3C1 interaction is highlighted) |
| PMC4009396__F2 | microRNAs in cancer |
| PMC4009444__F2 | Intracellular signaling pathways for hepcidin expression |
| PMC4009476__F1 | Hepatic fibrogenesis |
| PMC4009948__F1 | Cap-dependent and elongation translational control by GNRH |
| PMC4010202__F2 | Proposed signaling mechanisms underlying the protective effects of mood stabilizing drugs against experimental stroke |
| PMC4010328__F5 | TOB1 was involved in regulation of tumor growth and metastasis via the PI3K/PTEN signaling pathway |
| PMC4010977__F1 | Metabolic pathway for thymidine production |
| PMC4011321__F8 | Putative pathway of the inhibition of LPS-activated inflammatory signaling by compound 7 |
| PMC4011580__F6 | SCFBeta-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway |
| PMC4011666__F7 | Calcineurin Signaling Regulates Neural Induction Through Antagonizing the BMP Pathway |
| PMC4011807__F1 | Pathophysiology of anthrax illustrated as a series of steps |
| PMC4011959__F3 | The initial stages of vesicle elongation in macroautophagy |
| PMC4012154__F1 | Signaling pathways involved in microglial phagocytosis |
| PMC4012261__F6 | Graphical representation of the genomic neighborhoods of SRF and ZNF350 |
| PMC4012266__F2 | The autophagy process and signaling pathway |
| PMC4012311__F11 | Regulation of TRN mechanosensation |
| PMC4012776__F1 | Trim21 negatively regulates the DDX41-mediated signaling pathway |
| PMC4012865__F9 | Activation of DCs by HKBA showing the stimulation of TLR2 and TLR9 and cross-talk between their respective signal transduction pathways |
| PMC4012889__F1 | Intricate network of TLR signaling and miRNAs |
| PMC4012967__F1 | IL-6/JAK/STAT pathway |
| PMC4012993__F6 | Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation |
| PMC4013140__F7 | The Repressive Effect of miR-148a on TGF beta-SMADs Signal Pathway Is Involved in the Glabridin-Induced Inhibition of the Cancer Stem Cells-Like Properties in Hepatocellular Carcinoma Cells |
| PMC4013180__F3 | Multiple pathways can stimulate Beta-cell replication in obesity, and there is overlap of many of the downstream activators |
| PMC4013251__F1 | Canonical microRNA (miRNA) biogenesis pathway: miRNAs are initially transcribed as long, variable-length hairpin RNA substrates called primary miRNAs (pri-miRNAs) directly off the DNA template in the nucleus by RNA polymerase II (A) |
| PMC4013402__F1 | Glucose and glutamine metabolism in cancer cells |
| PMC4013405__F3 | nAChR-mediated signaling in lung squamous cell carcinomas and adenocarcinomas |
| PMC4013413__F2 | Roles of ALK in the pathogenesis of ALK+ anaplastic large cell lymphoma (ALCL) |
| PMC4013419__F1 | Major components of Sonic hedgehog (Shh) signaling pathway |
| PMC4013446__F2 | Functional significance of differentially expressed miRNAs–miRNA-512-5p, 190a and 200b-3p (Ingenuity pathway analysis) |
| PMC4013479__F1 | A simplified working model of the c-di-GMP signaling pathway in B |
| PMC4013519__F5 | cdc-42 regulates engulfment in response to PAT-2/CED-1-UIG-1 signaling |
| PMC4013580__F6 | A schematic model presenting the pathway of BMP4 to affect foam cell formation |
| PMC4013640__F2 | Pericyte physical and biochemical interactions at the NVU |
| PMC4013649__F7 | A20 on LPS signaling pathway |
| PMC4013670__F6 | Schematic describing the proposed anti-inflammatory response resulting from resveratrol treatment and its effects on TLR4 following stimulation of chondrocytes with IL-1B |
| PMC4013678__F2 | Bayesian Brain Immune and Microglia Module |
| PMC4014333__F1 | Biosynthetic pathway of prodigiosin |
| PMC4014576__F6 | Protein Tyrosine Phosphatases PTP-1B, SHP-2, and PTEN Facilitate Rb/E2F-Associated Apoptotic Signaling |
| PMC4014746__F1 | Canonical Wnt pathway [[]] |
| PMC4014913__F2 | Metabolic pathways of fatty acid (FA) and triacylglycerol (TAG) synthesis, and mechanisms by which lipid intermediates affect hepatic insulin sensitivity |
| PMC4015186__F1 | MiRNA Regulation of the Human Glycome |
| PMC4015186__F4 | Insights into MiRNA Regulation of the Human Glycome |
| PMC4015472__F2 | Post-Transcriptional Regulation of Interferons and Their Signaling Pathways |
| PMC4015472__F3 | Post-Transcriptional Regulation of Interferons and Their Signaling Pathways |
| PMC4015830__F2 | Intersection of BC modules 143, 79 and 82 |
| PMC4016161__F1 | The succinate dehydrogenase complex (SDH), as a member of the tricarboxylic acid cycle (TCA), catalyzes the oxidation of succinate to fumarate |
| PMC4016715__F2 | Ciliary-vesicle-dependent steps of ciliogenesis, and modular organization and mechanism of the IFT machinery |
| PMC4016715__F3 | Model depicting ciliary cargo trafficking pathways |
| PMC4016833__F1 | Signaling events in murine heart development and cardiac ESC differentiation |
| PMC4016892__F6 | Schematic model illustrating the signaling pathway by which ANG suppresses the inflammatory response involving TBK1-mediated NFKB nuclear translocation in HCFs inflamed by TNFA |
| PMC4016907__F5 | Both images were created using IPA |
| PMC4017002__F8 | PPARB/D promotes HRAS-induced senescence by potentiating p-ERK and repressing p-AKT |
| PMC4017039__F1 | Intracellular signal propagation of human toll-like receptors and corresponding ligands in innate immunity |
| PMC4017408__F1 | Wnt signaling pathway |
| PMC4017424__F1 | NFKB signaling pathways |
| PMC4017424__F4 | Activation of IKK pathway |
| PMC4017430__F1 | Leptin receptor signaling |
| PMC4017641__F1 | O-glycan biosynthesis/human version pathway |
| PMC4017675__F5 | In sum, there is a critical clinical need for better understanding and treatment of inflammatory airway disease in general, and mucous cell metaplasia in particular |
| PMC4018296__F5 | Chemical Genomic-Based Pathway Analyses for Epidermal Growth Factor-Mediated Signaling in Migrating Cancer Cells. |
| PMC4018400__F4 | De Novo Characterization of the Spleen Transcriptome of the Large Yellow Croaker (Pseudosciaena crocea) and Analysis of the Immune Relevant Genes and Pathways Involved in the Antiviral Response |
| PMC4018400__F5 | De Novo Characterization of the Spleen Transcriptome of the Large Yellow Croaker (Pseudosciaena crocea) and Analysis of the Immune Relevant Genes and Pathways Involved in the Antiviral Response |
| PMC4018451__F1 | The IRS-1→PI3K→Akt insulin signaling pathway |
| PMC4018451__F2 | Schematic summary of hippocampal formation alterations in the IR→IRS-1→PI3K→Akt→mTOR signaling pathway of AD dementia cases versus age- and gender-matched controls |
| PMC4018747__F4 | Pathways leading from ssDNA-bound RPA to the recruitment of an error-prone polymerase η, ι, K or Rev1 for bypass of a potential template lesion |
| PMC4019000__F1 | Dietary Fatty Acids and the Aging Brain |
| PMC4019002__F1 | Omega-3 fatty acids and dementia |
| PMC4019040__F1 | Mutated and wild-type tyrosine kinase activation in cancer |
| PMC4019268__F1 | Proposed mechanism underlying disrupted brain insulin signaling in Alzheimer's disease (AD) |
| PMC4019409__F2 | Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease |
| PMC4019504__F5 | Integrated Analysis of Genome-wide Copy Number Alterations and Gene Expression in MSS, CIMP-negative Colon Cancer |
| PMC4019579__F8 | NAMPT-Mediated Salvage Synthesis of NAD+ Controls Morphofunctional Changes of Macrophages |
| PMC4019832__F2 | Activation, signalling and targeting of ErbB receptor family members |
| PMC4020326__F2 | Glucogen-like peptide-1 and cancer |
| PMC4020352__F1 | Noncanonical transforming growth factor B signaling in scleroderma fibrosis |
| PMC4020352__F3 | Noncanonical transforming growth factor B signaling in scleroderma fibrosis |
| PMC4020801__F3 | Proteomics of Vitreous Humor of Patients with Exudative Age-Related Macular Degeneration |
| PMC4020998__F1 | Apigenin Modulates Insulin-like Growth Factor Axis: Implications for Prevention and Therapy of Prostate Cancer |
| PMC4021040__F2 | Targeting glioma stem cells: a novel framework for brain tumors |
| PMC4021255__F3 | Ingenuity Pathway Analysis of genes negatively regulated by unliganded GR |
| PMC4021255__F4 | Ingenuity Pathway Analysis of genes positively regulated by unliganded GR |
| PMC4021393__F2 | Activation of the "Role of BRCA1 in DNA Damage Response' pathways in NCR versus CR samples |
| PMC4021462__F4 | Central metabolic pathway proteome at different growth conditions |
| PMC4021516__F7 | Wild-type p53 (WT-p53) and mutant p53 differentially regulate Nox4 expression in both TGF-Beta-dependent and independent mechanisms |
| PMC4021575__F3 | Ribosome assembly and Insulin signalling pathway |
| PMC4021685__F1 | Schematic simplified demonstration of the main mechanisms supposed to be involved in fatty acid and TNF family interaction at different levels of colon epithelial cell organisation |
| PMC4022041__F3 | Genes involved in the TGF beta signaling pathway after 5 days |
| PMC4022110__F1 | Schematic overview of MBL-dependent activation of the lectin pathway of complement |
| PMC4022192__F5 | TLR-induced signalling pathways |
| PMC4022194__F2 | Signalling pathways that were altered in the high serum [P] group |
| PMC4022581__F4 | Transcriptome Profiling of the Theca Interna in Transition from Small to Large Antral Ovarian Follicles |
| PMC4022607__F1 | Angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development |
| PMC4023029__F7 | Proposed pathway for activation/proliferation of alloantigen-specific nTreg and comparison with the non-antigen driven proliferation of nTreg that do not have a TCR specific for the antigen |
| PMC4023047__F3 | Role of POR in biosynthesis of androgens in classic and alternate pathways |
| PMC4023177__F3 | Key signaling pathways involved in the early recurrence/metastasis (R/M≤6months) and late recurrence/metastasis (R/M6-12months) of H-HCC |
| PMC4023229__F2 | Neural tube defects - recent advances, unsolved questions and controversies |
| PMC4023255__F5 | TGFB family signaling for Müllerian duct regression |
| PMC4023360__F1 | Role of Heat shock protein-27 (HSP27) and clusterin (CLU) in cancer cell survival |
| PMC4023363__F1 | PI3K-AKT-mTOR signaling pathway and therapeutic opportunities |
| PMC4023701__F5 | Crosstalk pathway |
| PMC4023801__F2 | Proposed metabolic activation pathway of GS-6620 |
| PMC4023818__F10 | Working model |
| PMC4023866__F1 | Bacterial effectors that target and manipulate the innate immune and inflammatory pathways |
| PMC4023931__F3 | Digital Expression Profiling Identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as Potential Predictive Biomarkers for Neo-Adjuvant Chemotherapy Response in Paediatric Osteosarcoma |
| PMC4024059__F1 | STAT3 and epithelial-mesenchymal transitions in carcinomas |
| PMC4024337__F4 | NFKB gene signature predicts prostate cancer progression. |
| PMC4024346__F1 | The ERK1/2 MAPK signaling network controlled by receptor tyrosine kinases and Ras |
| PMC4024417__F1 | Crosstalk between TGFB signaling and the renin-angiotensin system in fibrosis |
| PMC4025940__F1 | Roles of TGFB in the tumour microenvironment |
| PMC4025998__F2 | Mechanism of white matter damage in SHR-SP |
| PMC4026009__F3 | Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies |
| PMC4026077__F1 | Inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells |
| PMC4026305__F1 | Nox NADPH Oxidases and the Endoplasmic Reticulum |
| PMC4026364__F1 | Tumor Suppressor p53 and Estrogen Receptors in Nuclear-Mitochondrial Communication |
| PMC4026397__F2 | Role of NADPH Oxidases in Liver Fibrosis |
| PMC4026397__F4 | Role of NADPH Oxidases in Liver Fibrosis |
| PMC4026543__F2 | EPH receptors crosstalk with EMT-related signaling pathways |
| PMC4026680__F1 | Early life stress can influence development of the HPA axis, as well as regulation of satiety-related hormones, leptin, insulin, and ghrelin to alter feeding behavior long-term |
| PMC4026697__F3 | VKR signaling pathways |
| PMC4026703__F1 | Schematic diagram showing the central role of the BMP6-HJV-SMAD signaling pathway in hepcidin regulation and the proposed interaction with other hepcidin regulators |
| PMC4026741__F1 | Pattern recognition receptors in respiratory anti-viral immunity |
| PMC4026869__F6 | Gene network of 32 genes with pathway level expression change and mutation via GeneMANIA |
| PMC4026919__F1 | Wnt signaling pathway |
| PMC4027041__F1 | Hepatic S-adenosylmethionine (SAMe) metabolism |
| PMC4027049__F2 | TGFB signalling in context |
| PMC4027966__F3 | Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes |
| PMC4028332__F2 | After the banquet |
| PMC4028364__F1 | Conservation of host cells and pathogen categories in zebrafish and mammalian infection by eukaryotes |
| PMC4028717__F7 | Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor pathway |
| PMC4028786__F1 | Homocysteine metabolic pathways |
| PMC4028840__F1 | PI3K/Akt/mTOR signaling pathway [[]] |
| PMC4029299__F3 | Gene- and pathway-based connectivity map of vismodegib and Gorlin syndrome |
| PMC4029488__F1 | Basic regulation mechanisms required in the process of a cell utilizing glucose and glycogen |
| PMC4029488__F2 | HFPN model of extended center metabolism pathway in E |
| PMC4029595__F7 | Proposed breast cancer signaling pathway based on the KEGG network pathway analysis of hypoxia-activated tumor cell migration |
| PMC4029773__F1 | JAK-STAT signaling in adipose tissue function |
| PMC4029965__F7 | Predicting Response to Preoperative Chemotherapy Agents by Identifying Drug Action on Modeled MicroRNA Regulation Networks |
| PMC4030106__F1 | Roles of IL-21 and IRF4 in immune and metabolic regulation |
| PMC4030113__F2 | Abnormalities in IRS1 interaction in the KEGG PI3K-AKT signaling pathway (PI3K-AKT) |
| PMC4030113__F3 | Abnormalities in IRS1 interaction in the KEGG Oxidative Phosphorylation metabolic pathway |
| PMC4030154__F2 | Metals and cholesterol implicated in AB processing and neurotoxicity |
| PMC4030405__F1 | Complement system |
| PMC4030640__F2 | Molecular and biophysical characterization of the human blood-nerve barrier: Current concepts |
| PMC4030844__F1 | Simplified schema of interconnections between small ubiquitin-related modifier (SUMO) pathway proteins and other factors regulating androgen receptor (AR)-dependent transcription |
| PMC4030844__F2 | AR-independent promotion of prostate cancer (PCa) cell proliferation and angiogenesis by the SUMO pathway |
| PMC4030989__F1 | Sphingolipid pathway and basic structural units of sphingolipid biosynthesis |
| PMC4031100__F3 | Nutritional metabolomics: Progress in addressing complexity in diet and health |
| PMC4031321__F1 | HIV induction by PKC activators and HDAC and BET inhibitors: NFKB is sequestered in the cytoplasm by IKB |
| PMC4031445__F2 | Signal transduction by prostaglandin receptor EP2 |
| PMC4031539__F5 | Summary figure of the switch from Pu.1 interaction with coactivators to corepressors caused by Runx1 deficiency |
| PMC4031758__F2 | Wnt signaling pathway |
| PMC4031942__F13 | Anti-inflammatory mechanism of C3G is associated with upregulation of the LXRAlpha-ABCG1 pathway which results in disrupting lipid rafts by depleting cholesterol, thereby suppressing the TLR4-mediated NFKB and IRF3 signaling pathways induced by LPS |
| PMC4031983__F8 | MiRNA dependent regulation of DSB repair during cell cycle |
| PMC4032097__F9 | CNTF-induced gliosis in the retina after ONC and Pen1-C6DN + siCASP2 treatment |
| PMC4032125__F7 | Molecular Evolution of the Yap/Yorkie Proto-Oncogene and Elucidation of Its Core Transcriptional Program |
| PMC4032270__F3 | Oak Root Response to Ectomycorrhizal Symbiosis Establishment: RNA-Seq Derived Transcript Identification and Expression Profiling |
| PMC4032345__F3 | Comparative Proteomic Analyses Provide New Insights into Low Phosphorus Stress Responses in Maize Leaves |
| PMC4032603__F3 | KIBRA in Hippo pathway |
| PMC4032668__F3 | Simplified scheme of the DAF-16 signalling pathway in C |
| PMC4032983__F6 | CK1 in Wnt-signaling |
| PMC4032983__F8 | CK1 in Hippo signaling in vertebrates |
| PMC4033011__F2 | Possible pathways for LRP1-mediated AB uptake |
| PMC4033012__F2 | Schematic representation of the NALCN channelosome |
| PMC4033420__F1 | Colorectal cancer MSI and CIN signaling pathways modified from KEGG database |
| PMC4033570__F5 | Simplified network diagram showing the involvement of JNK and p38 in the system |
| PMC4033628__F2 | Synthesis of representative structures along the Golgi-centric core M1 and M2 glycan synthesis pathways |
| PMC4033628__F3 | Representative core M3 structures that are dependent on multiple initial activities based in the ER |
| PMC4034039__F5 | Proposed lignin degradation pathway in C |
| PMC4034063__F1 | Core hypothalamic energy homeostatic circuit and the dopamine reward pathway |
| PMC4034110__F1 | Mitochondrial and metabolic checkpoints of T-cell activation and apoptosis signals |
| PMC4034385__F1 | Chromatin modifications as therapeutic targets in MLL-rearranged Leukemia |
| PMC4034436__F1 | Effects of the HIF pathway on mesenchymal stem cells (MSCs) |
| PMC4035704__F3 | Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP |
| PMC4036091__F2 | Schematic diagram representing the hypothetical mechanisms of the insulin-dependent systemic (I) and insulin-independent direct (II) effects of metformin in the endometrium |
| PMC4036111__F3 | Schematic of the FGFR signaling pathway |
| PMC4036234__F2 | Cargo recognition and packaging in selective macroautophagy |
| PMC4036287__F9 | Working model for Fas signaling in cancer-related inflammation and breast cancer progression |
| PMC4036317__F11 | How PLCG1 regulates USP1 phosphorylation to mediate 20E-induced gene expression for metamorphosis |
| PMC4036353__F8 | How TAZ/YAP direct TGFBeta-induced tumorigenic events |
| PMC4036354__F1 | Cross-talk between Two Signaling Pathways Drives Aggressive Late-stage Breast Cancer♦ |
| PMC4036579__F7 | Methylcrotonyl-CoA Carboxylase Regulates Triacylglycerol Accumulation in the Model Diatom Phaeodactylum tricornutum. |
| PMC4037130__F1 | Targeting protein prenylation for cancer therapy |
| PMC4037312__F3 | PI3K/AKT/PTEN signaling, which modulate NOXs-derived ROS |
| PMC4037353__F1 | MicroRNA regulation of the germinal center response |
| PMC4037363__F3 | Trafficking of endosomal Toll-like receptors |
| PMC4037387__F2 | JAK/STAT pathway dysregulation in tumors: A Drosophila perspective |
| PMC4037811__F1 | An Inside View: VEGF Receptor Trafficking and Signaling |
| PMC4037835__F1 | The MDC-MMSET-UBC9-53BP1-BRCA1 pathway |
| PMC4037911__F1 | Bid can be activated by multiple proteases in response to a variety of pathophysiological signals |
| PMC4037924__F1 | Ancestral Ca2+ Signaling Machinery in Early Animal and Fungal Evolution |
| PMC4037996__F1 | Intracellular signalling pathway originating at EGFR and inducing the activation of proliferation, inhibition of apoptosis, and differentiation of epithelial and cancer cells |
| PMC4037996__F2 | Role of normal and mutated KRAS protein in the regulation of the signalling pathway associated with EGFR activation |
| PMC4038158__F3 | Signaling pathway initiated by Edn1-induced Ednra signaling |
| PMC4038253__F1 | Simplified scheme of the N-glycosylation pathway |
| PMC4038461__F6 | Finding Novel Molecular Connections between Developmental Processes and Disease |
| PMC4038464__F3 | Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease |
| PMC4038542__F1 | Complement activation and effector functions |
| PMC4038907__F4 | Progesterone and breast cancer |
| PMC4038991__F4 | Circadian Redox and Metabolic Oscillations in Mammalian Systems |
| PMC4039002__F9 | Aggregate-Prone R120GCRYAB Triggers Multifaceted Modifications of the Thioredoxin System |
| PMC4039115__F5 | Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another "double hit" lymphoma with very poor outcome? |
| PMC4039369__F1 | Yeast pathway map of nucleotide degradation and ribose salvage |
| PMC4039567__F8 | De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways |
| PMC4039984__F1 | Chromatin Landscape and Transcription Factors in T-Cell Programming |
| PMC4039991__F1 | Upregulation of a Steroid Synthesis Pathway in Th2 Cells In Vitro(A) Schematic representation of integrated steroid biosynthesis pathway with abbreviated metabolites (black) and protein factors (blue) |
| PMC4040260__F2 | Apoptotic cell clearance: basic biology and therapeutic potential |
| PMC4040287__F4 | SIRT1 in neurodevelopment and brain senescence |
| PMC4040351__F2 | From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling |
| PMC4040351__F4 | From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling |
| PMC4040584__F1 | Expansion of the SDF-1/CXCR4 migratory signaling network in breast cancer stem cells |
| PMC4040598__F5 | Model depicting effect of ADAM17 variant on the canonical TGFB signaling pathway |
| PMC4040611__F5 | An MAPK network downstream of SDF-1/CXCR4 signaling in breast CSCs |
| PMC4040708__F1 | HCV apoptotic signaling pathways |
| PMC4040894__F2 | Heme biosynthesis |
| PMC4040907__F6 | The impact of 5q deletion upon myeloid cell fate |
| PMC4040939__F2 | Wnt pathway, sclerostin, and DKK1; effects of monoclonal antibodies on bone.(a) Scl and DKK1 bind Wnt coreceptors LRP5/6 to inhibit Wnt binding and signaling to decrease bone formation |
| PMC4040986__F2 | An Expanded Genomic Representation of the Phylum Cyanobacteria |
| PMC4041145__F1 | Akt and NFKB signaling in drug resistance mechanism of tumor cells |
| PMC4041276__F8 | Signaling pathways mediating DON-induced RSR, including the MAPK (A, blue), NFKB (B, red), AKT and AMPK pathways (C, green) |
| PMC4041457__F4 | The SDSA (synthesis-dependent strand annealing) and DSB repair sub-pathways |
| PMC4041713__F2 | Differential Expression of MicroRNA and Predicted Targets in Pulmonary Sarcoidosis |
| PMC4041713__F4 | Differential Expression of MicroRNA and Predicted Targets in Pulmonary Sarcoidosis |
| PMC4041745__F4 | Systematic Pathway Enrichment Analysis of a Genome-Wide Association Study on Breast Cancer Survival Reveals an Influence of Genes Involved in Cell Adhesion and Calcium Signaling on the Patients' Clinical Outcome |
| PMC4041745__F5 | Systematic Pathway Enrichment Analysis of a Genome-Wide Association Study on Breast Cancer Survival Reveals an Influence of Genes Involved in Cell Adhesion and Calcium Signaling on the Patients' Clinical Outcome |
| PMC4041745__F6 | Systematic Pathway Enrichment Analysis of a Genome-Wide Association Study on Breast Cancer Survival Reveals an Influence of Genes Involved in Cell Adhesion and Calcium Signaling on the Patients' Clinical Outcome |
| PMC4041829__F1 | Overview of cellular Na+ transport mechanisms and important components of the salt stress response network in plant root cells |
| PMC4042218__F7 | Schematic representation of the blocking effect of sorafenib on development of left ventricle hypertrophy (LVH) induced by aortic banding |
| PMC4042299__F3 | The role of epigenetics in the biology of multiple myeloma. |
| PMC4042557__F4 | Graphical overview of the Canonical Pathway analysis |
| PMC4042834__F4 | An example of a KEGG pathway containing genes involved in multiple processes |
| PMC4043133__F9 | Proposed site of PEP7 inhibition of the AT1R-Erk1/2 signaling cascade |
| PMC4043215__F1 | Hypoxia-Activated Pathways Leading to Cancer Stem Cell Maintenance |
| PMC4043666__F7 | Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships |
| PMC4043736__F3 | Patterns of Gene Expression Associated with Pten Deficiency in the Developing Inner Ear |
| PMC4043860__F2 | Transcriptional control of spermatogonial maintenance and differentiation |
| PMC4043871__F2 | Testosterone signaling pathways in Sertoli cells |
| PMC4043921__F4 | Cytoskeletal proteins in cerebral cavernous malformation signaling pathways |
| PMC4044302__F1 | Sites of thyroid hormone regulation of metabolism |
| PMC4045235__F3 | CUL7-OBSL1-CCDC8 pathway and its predicted role in cell growth |
| PMC4045475__F1 | MUC1: A Novel Metabolic Master Regulator |
| PMC4045475__F3 | MUC1: A Novel Metabolic Master Regulator |
| PMC4045488__F1 | MicroRNAs in pancreatic cancer metabolism |
| PMC4046017__F4 | Inhibition of IFNg signaling by MAP |
| PMC4046121__F5a | Differential Transcription of Fathead Minnow Immune-related Genes Following Infection with Frog virus 3, an Emerging Pathogen of Ectothermic Vertebrates |
| PMC4046179__F5 | 98 proteins that showed significant changes in oxidation levels with HFHS diet were subjected to IPA |
| PMC4046186__F1 | Intrinsic and extrinsic apoptosis signaling pathways (adapted from ref |
| PMC4046345__F2 | dsRNA-Activation of TLR3 and RLR Signaling: Gene Induction-Dependent and Independent Effects |
| PMC4046519__F4 | Network analysis performed on converging genes differentially regulated in response to different stresses in mouse and between different selected Flinders lines |
| PMC4046566__F2 | Application of the algorithm to identify TNBC-associated genes |
| PMC4046645__F2 | Overview of molecular pathways of oxidative stress and potential points of intervention in T cells in SLE |
| PMC4046670__F6 | Prioritized genes in apoptosis and TNFR2 signaling pathways |
| PMC4046911__F2 | PI3K-AKT signaling is a downstream effector of retinoid prevention of murine basal cell carcinogenesis |
| PMC4047132__F2 | Cellular functions of proteins commonly mutated in uveal melanoma |
| PMC4047366__F11 | Metabolic feedback via HBP and N-glycan branching |
| PMC4047762__F6 | ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway |
| PMC4047858__F7 | Combined metabolomics-transcriptomics identification of pathways affected by MPP+ |
| PMC4048572__F8 | Exercise-Induced Skeletal Muscle Remodeling and Metabolic Adaptation: Redox Signaling and Role of Autophagy |
| PMC4048575__F1 | Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival |
| PMC4048575__F5 | Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival |
| PMC4048824__F2 | Pathways for sulfide biogenesis and clearance |
| PMC4048856__F2 | HEPCIDIN AND IRON HOMEOSTASIS |
| PMC4048895__F8 | Proposed model for the role of miR-26a in pulmonary fibrosis |
| PMC4048946__F1 | Metabolic pathways regulating oxidative stress and endosome traffic controlling the recycling of receptor and adaptor proteins between the cell surface and lysosomes |
| PMC4048950__F10 | Redox control of p53 in the transcriptional regulation of TGFB1 target genes through SMAD cooperativity |
| PMC4049336__F3 | Clinically validated resistance mechanisms to EGFR inhibitors |
| PMC4049637__F1 | Functional Conservation of Coenzyme Q Biosynthetic Genes among Yeasts, Plants, and Humans |
| PMC4049685__F2 | Colorectal cancer metastasis signaling pattern |
| PMC4049797__F4 | Multiple lesions in receptor tyrosine kinase pathway determine glioblastoma response to pan-ERBB inhibitor PF-00299804 and PI3K/mTOR dual inhibitor PF-05212384 |
| PMC4049860__F3 | CCM1 and the second life of proteins in adhesion complexes |
| PMC4049898__F2 | Wnt and planar cell polarity signaling in cystic renal disease |
| PMC4049967__F1 | IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF) |
| PMC4050127__F1 | Targeting LIM kinase in cancer and neurofibromatosis |
| PMC4050178__F1 | Brief Overview of DNA Damage Repair: Three common types of DNA damage are depicted in this image as well as an summary of the pathways/proteins that are activated in response to each type of damage |
| PMC4050248__F7 | Protein kinase C epsilon (PKCÉ›) is a major regulator of mitochondrial nicotinamide phosphoribosyltransferase (Nampt) and nicotinamide adenine dinucleotide (NAD) |
| PMC4050335__F3 | Canonical and non-canonical pathway leading to the activation of NFKB |
| PMC4050365__F5 | Single-stranded RNA loading to AGO-clade Argonaute proteins |
| PMC4050496__F2 | Notch: Architect, Landscaper, and Guardian of the Intestine |
| PMC4050971__F3 | Ingenuity Pathway Analyses: Pathway analyses were from the commercially available Ingenuity Pathway Analysis software |
| PMC4050971__F4 | Ingenuity Pathway Analyses: Details are as in |
| PMC4051134__F3 | Targeting JAK2 in the therapy of myeloproliferative neoplasms |
| PMC4051134__F5 | Targeting JAK2 in the therapy of myeloproliferative neoplasms |
| PMC4051158__F1 | Role of the CD40-CD40L pathway during the CD8 primary response |
| PMC4051158__F5 | The CD40-CD40L pathway plays a critical role in CD4 T-cell-mediated IL-21 production during the rescue of exhausted T-cell response |
| PMC4051169__F8 | Mitotic roles of Polo-like kinase pathway |
| PMC4051228__F1 | The folate/Hcy metabolic pathway |
| PMC4051248__F9 | LPS up-regulates the PhT2 signaling pathway |
| PMC4051344__F1A | Regulation of Inflammation in Cancer by Eicosanoids |
| PMC4051765__F1 | Responses of the Insulin Signaling Pathways in the Brown Adipose Tissue of Rats following Cold Exposure |
| PMC4051800__F6 | Causal BN learned from breast cancer cases for the ErbB pathway |
| PMC4051845__F1 | DNA double-strand break repair pathway choice and cancer |
| PMC4051924__F5 | Top-ranked signaling networks related to Na+/K+/2Cl- cotransporter 1 downregulation according to ingenuity pathway analysis |
| PMC4051995__F2 | Mammary Development and Breast Cancer: The Role of Stem Cells |
| PMC4052099__F1 | Predicted insulin signaling pathway in schistosomes based on the characterization of schistosome insulin receptors, the published S |
| PMC4052186__F2 | Cross-talk between mitochondrial metabolism and the IIS pathway is required to trigger the mitohormetic response in C |
| PMC4052206__F6 | Ingenuity pathway analysis (IPA) displaying regulatory relationships among highly expressed (green) and lower (red) placental transcripts in less muscular women as compared with women with high arm muscle area |
| PMC4052302__F10 | General overview of TLR4 signaling in humans |
| PMC4052347__F5 | PPI network and signaling pathway analysis |
| PMC4052589__F1 | Possible mechanisms of the opioid receptor-mediated influence of morphine on tumor growth |
| PMC4052696__F7 | Based on experimental data GDS3634, miR-205 expression effect on prostate cancer cell line, from NCBI public database browser, P value of 8 samples of Student's t-test, microarray data was applied as the link cost for predicted paths |
| PMC4052696__F9 | Pathway Bridge Based Multiobjective Optimization Approach for Lurking Pathway Prediction. |
| PMC4052759__F1 | Autophagy regulates p62/SQSTM1 levels to control multiple pro-oncogenic signaling pathways |
| PMC4052811__F2 | Deduced pathway of sterol biosynthesis in N |
| PMC4052840__F2 | Therapeutics in development that target survival pathways activated by LMP1 and LMP2a |
| PMC4053166__F1 | Meet the terminator: the phosphatase PP2A puts brakes on IRF-3 activation |
| PMC4053266__F3 | Integrative pathway analysis |
| PMC4053348__F1 | Role of MALT1 in signaling to NFKB in ABC DLBCL |
| PMC4053506__F8 | D-PDMP inhibits ox-LDL induced LCS activity and atherosclerosis development |
| PMC4054275__F11 | Proposed regulatory mechanism of protein tyrosine phosphatases in C |
| PMC4054417__F3 | Distinct regulation of apoptosis pathway genes in neurons and fibroblasts in response to VZV infection |
| PMC4054791__F1 | Schematic representation of the photorespiratory pathway (in black) and the three circumvent pathways designed to overcome the photorespiratory losses |
| PMC4054936__F2 | Tonic regulation of vascular permeability |
| PMC4055129__F1 | Inhibition mechanism of MTX in DNA synthesis pathway |
| PMC4055201__F8 | Schematic diagram illustrating the possible mechanisms responsible for CORM-2 effects on LPS-induced VCAM-1 expression in RASFs |
| PMC4055208__F8 | Scheme representing the insulin signalling pathway, the mechanisms involved in the high glucose-induced impairment of the insulin pathway and the proposed mechanism by which PPARB agonists prevent high glucose-induced insulin resistance in HUVECs |
| PMC4055569__F8 | Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference |
| PMC4055761__F3 | Chromatin Remodelling Induced by the Freshwater Cyanotoxin Cylindrospermopsin in Human Intestinal Caco-2 Cells |
| PMC4055784__F2 | The interactome space of the edible plants associated to colon cancer |
| PMC4055840__F5 | Hypothetical model illustrating possible molecular mechanisms underlying the action of the glucocorticoid receptor in the excitation-inhibition balance in NPCs |
| PMC4055851__F2 | Resistance to anti-EGFR moAbs in mCRC |
| PMC4055861__F2 | Base excision repair (BER) pathway |
| PMC4055918__F1 | Erythroid DAMPs drive inflammation in SCD |
| PMC4055924__F6 | CD28 signaling in myeloma cells |
| PMC4056054__F1 | Co-culture with M38 melanoma upregulate interferon signalling pathways |
| PMC4057083__F8 | On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio |
| PMC4057133__F6 | Summary of signaling events leading to PRKD2-dependent induction of senescence in p53wt and p53mut GBM cells |
| PMC4057522__F8 | Possible mechanism implicated in tamoxifen resistance in the TAMR cell line model |
| PMC4057583__F10 | Link between NFKBIA and EGFR pathway in Glioblastoma |
| PMC4057758__F6 | Graphical representation of two of the top score networks identified by Ingenuity Pathway Analysis (IPA) |
| PMC4057789__F1 | Cross-talk between EpCAM signaling and the Wnt pathway |
| PMC4057899__F8 | Schematic diagram |
| PMC4058004__F1 | Simplified biotransformation scheme of tamoxifen in man. Tamoxifen is mainly N-demethylated to NDM-TAM and subsequently 4-hydroxylated to endoxifen |
| PMC4058013__F3 | KLK5 protease suppresses breast cancer by repressing the mevalonate pathway |
| PMC4058194__F6 | In mTOR signaling pathway, there is the triplet of genes codes for proteins (orange nodes), and the pair (ATM and TP53) corresponds to interacting proteins in the cell cycle pathway (light blue nodes) |
| PMC4058194__F8 | RTK/RAS/PI(3)K signaling pathway |
| PMC4058364__F7 | HRG-mediated signaling via mTORC2 to mTORC1 |
| PMC4058638__F1 | Core phosphatases of the PI 3-Kinase pathway |
| PMC4058660__F1 | PI3K signaling in normal neural function and LTP induction |
| PMC4058660__F2 | PI3K signaling in neural aging and disease |
| PMC4059147__F5 | Scheme for GAG biosynthesis (chondroitin/dermatan and heparan sulfate synthesis and keratan sulfate synthesis pathway) (A) and degradation (B) |
| PMC4059167__F1 | Canonical catecholaminergic neuron is one that generates dopamine, noradrenaline or adrenaline |
| PMC4059820__F2 | Signaling through T1R2/T1R3 in type II cells of taste buds, in the gut and in the B cells of the pancreas |
| PMC4059866__F4 | Gene network generated by Ingenuity Pathway Analysis of 5 genes identified to be predicted targets of miRNAs associated with in vitro cisplatin resistance (fold change > 2, P < 0.05) in the current study |
| PMC4059942__F1 | The main Notch pathway components |
| PMC4060077__F1 | Molecular switching from apoptosis to necroptosis |
| PMC4060203__F1 | Schematic showing the details of the estrogen pathway |
| PMC4060285__F6 | Schematic showing the protein acetylation sites in metabolic pathways that are most differentially acetylated in LDKO/flox liver |
| PMC4060523__F2 | Signaling pathways that positively regulate ecdysteroidogenesis in the PG in Drosophila melanogaster |
| PMC4060531__F3 | Genetic Basis of Diffuse Large B Cell Lymphoma |
| PMC4061041__F6 | ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence |
| PMC4061161__F1 | The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment. |
| PMC4061164__F1 | Cisplatin-induced inflammation is mediated through multiple effectors including activation of NFkB, TNFA, and PARP |
| PMC4061222__F1 | Roles of Wnt5a in cancer metastasis- (A) promoting and (B) suppressive processes |
| PMC4061247__F3 | Nuclear Trafficking in Health and Disease |
| PMC4061475__F1 | Dopamine biosynthetic pathway |
| PMC4061726__F1 | Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease |
| PMC4061808__F4 | Exercise activates a wide variety of intracellular signal transduction pathways to promote neurogenesis of granule cells from neuroprogenitors in the dentate gyrus |
| PMC4061845__F2 | Sphingolipid involvement in ethanol-induced apoptosis in the P7 mouse brain |
| PMC4061877__F4 | Hypothetical outcomes for demyelinated axon.Denuded axon impermissive for myelination |
| PMC4062707__F2 | Signalling pathways activated by chemokine receptors |
| PMC4062840__F2 | Regulation of Akt phosphorylation |
| PMC4062840__F3 | Components of the two mTOR complexes |
| PMC4062952__F1 | Four androgen metabolism pathways to DHT synthesis |
| PMC4062953__F1 | Steroid hormone synthesis pathways in the adrenal gland and testis |
| PMC4062953__F2 | Classical and non-classical pathways of androgen biosynthesis |
| PMC4063317__F5 | Receptors and cellular signaling pathways implicated in the antitumor effect of ANP |
| PMC4063399__F2 | Resistance to vemurafenib |
| PMC4063414__F3 | Phosphoglycerate mutase 1 (PGAM1) controls the levels of allosteric regulators 3-phosphoglycerate and 2-phosphoglycerate |
| PMC4063500__F2 | Lithium's autophagy regulation mechanism in various neuropsychiatric diseases |
| PMC4063740__F8 | Regulation of Schistosoma mansoni Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway |
| PMC4063840__F2 | In vivo gut transcriptome responses to Lactobacillus rhamnosus GG and Lactobacillus acidophilus in neonatal gnotobiotic piglets |
| PMC4063996__F2 | ErbB Receptors |
| PMC4064057__F3 | Genotype-specific steatogenic pathways associated with hepatitis C virus infection[-] |
| PMC4064060__F1 | The Wnt/Beta-catenin signaling in epithelial cells |
| PMC4064060__F4 | Molecular interactions between Wnt/Beta-catenin and PPARG signaling in colorectal cancer cells |
| PMC4064064__F3 | MicroRNAs and Toll-like receptor signaling pathway in hepatitis B virus infection |
| PMC4064254__F2 | An atlas of genetic influences on human blood metabolites |
| PMC406426__F1 | What is the role of mTLR7 in the antiviral response? Many ssRNA viruses (including VSV and influenza viruses) engage host cell receptors that trigger endocytosis |
| PMC4064697__F2 | Schematic summary of the photoneuroendocrine control of food intake and body weight |
| PMC4064721__F1 | Scheme of participation of MC1R in regulation of melanogenesis |
| PMC4064721__F2 | Scheme of the impact of MC1R on development of melanoma |
| PMC4064789__F8 | The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer |
| PMC4064951__F2 | Resistance to BRAF inhibitors: intrinsic and extrinsic mechanisms.Notes: Multiple different mechanisms have been described in resistance to BRAF inhibitors |
| PMC4065011__F5 | Ablation of Coactivator Med1 Switches the Cell Fate of Dental Epithelia to That Generating Hair |
| PMC4065097__F1 | Simulation of Swanson's Literature-Based Discovery: Anandamide Treatment Inhibits Growth of Gastric Cancer Cells In Vitro and In Silico |
| PMC4065255__F1 | Core components of the insulin-like signaling pathway in C |
| PMC406534__F1 | Proteolytic processing of APP is divided into an amyloidogenic and an antiamyloidogenic pathway |
| PMC4065383__F2 | Origins and removal of ribonucleotides in DNA |
| PMC4065631__F2 | Ligand bias prevents class equality among beta-blockers |
| PMC4065761__F1 | Current models of the signaling pathway of the spindle assembly checkpoint (SAC) |
| PMC4065826__F2 | MAP kinase signaling in SC plasticity |
| PMC4065997__F2 | Potentiation of growth factor signaling pathways involved in cell cycle progression in liver regeneration |
| PMC4066219__F2 | IL-15: a central regulator of celiac disease immunopathology |
| PMC4066235__F3 | microRNAs in Cancer Cell Response to Ionizing Radiation |
| PMC4066235__F4 | microRNAs in Cancer Cell Response to Ionizing Radiation |
| PMC4066235__F5 | microRNAs in Cancer Cell Response to Ionizing Radiation |
| PMC4066235__F7 | microRNAs in Cancer Cell Response to Ionizing Radiation |
| PMC4066335__F3 | All diabetes drugs are likely to have indirect effects in the CNS by affecting circulating concentrations of glucose and insulin |
| PMC4066587__F2 | The stomatal signaling pathway |
| PMC4066639__F5 | Stress-signaling pathways in C |
| PMC4066640__F5 | MYC autorepression and general cellular gene repression by histone modification |
| PMC4066641__F1 | Apoptotic signaling pathways in normal and malignant cells |
| PMC4066644__F2 | Model of tumor heterogeneity |
| PMC4066667__F3 | Current understanding of molecular mechanisms regulating spermatogonial stem cell (SSC) self-renewal in mice |
| PMC4066870__F4 | Smoke mediates EGFR/Src-dependent and independent cell migration |
| PMC4066980__F4 | Model for Id1 regulation of melanocyte growth and melanoma development |
| PMC4066991__F1 | Missing Link between Itch and Inflammation in Atopic Dermatitis |
| PMC4067122__F6 | Schematic drawing of the Hippo pathway in human EC |
| PMC4067728__F3 | Molecular actions of 1,25(OH)2D3 in inflammation and energy homeostasis in adipocytes |
| PMC4067916__F1 | The Hippo pathway in mammals |
| PMC4067963__F10 | Model of Sox9, Sox10 and FGF function during lacrimal gland branching morphogenesis |
| PMC4068075__F3 | Consequences of EMT on innate signaling |
| PMC4068281__F3 | Signaling pathways and transcription factors supporting or affecting the barrier phenotype of CNS-ECs |
| PMC4068285__F4 | LM infection in microglia |
| PMC4068945__F4 | Nrf2-mediated oxidative stress response pathway is altered at multiple levels by DNA methylation in COPD airways |
| PMC4069059__F7 | Receptor Interactive Protein Kinase 3 Promotes Cisplatin-Triggered Necrosis in Apoptosis-Resistant Esophageal Squamous Cell Carcinoma Cells |
| PMC4069163__F6 | Correction: De Novo Characterization of the Spleen Transcriptome of the Large Yellow Croaker (Pseudosciaena crocea) and Analysis of the Immune Relevant Genes and Pathways Involved in the Antiviral Response |
| PMC4069269__F1 | IL-18 signaling |
| PMC4069271__F1a | Hypoxia-Inducible Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (HIF-1B): Is It a Rare Exception? |
| PMC4069315__F1 | Mechanisms of action of lactic acid bacteria via extrinsic and intrinsic pathways of apoptosis[,] |
| PMC4069674__F1 | Suppression of metastasis by mirtazapine via restoration of the Lin-7C/Beta-catenin pathway in human cancer cells |
| PMC4069681__F1 | Rho protein GTPases and their interactions with NFKB: crossroads of inflammation and matrix biology |
| PMC4070007__F1 | Simplified diagram of the TLR-mediated and interferon (IFN)-mediated immunity in response to viruses |
| PMC4070062__F1 | TLRs and autophagy |
| PMC4070062__F3 | Cytosolic nucleic acids sensors and autophagy |
| PMC4070521__F1 | Biosynthetic pathway of n3 and n6 PUFAs highlighting a set of genes known to play key roles in the biosynthesis and metabolism of LC-PUFAs in two parallel and competing pathways |
| PMC4070857__F2 | The primary mechanisms through which vitamin D-regulated dendritic cells (DCs) and T-lymphocyte function.Notes: vitamin D precursors can be further processed to their active metabolite, 1,25(OH)2D3, in DCs and T lymphocytes |
| PMC4071053__F2 | Molecular network generated by Ingenuity Pathway Analysis (IPA) of highly significant gene changes in human RPE cells after in vitro stimulation with AGE (10 µg/mL) |
| PMC4071053__F3 | Interferon Signaling Pathway identified by Ingenuity software |
| PMC4071059__F3 | Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?. |
| PMC4071201__F1 | Depiction of the systematic procedure to study drug resistance in MM |
| PMC4071201__F2 | p38 MAPK isoforms for drug resistance |
| PMC4071223__F7 | Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis |
| PMC4071401__F11 | Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis |
| PMC4072077__F1 | MicroRNAs (miRNAs) are involved in pathogenesis of multiple myeloma (MM) by targeting some signaling pathways in myeloma cells |
| PMC4072629__F3 | VPA Alleviates Neurological Deficits and Restores Gene Expression in a Mouse Model of Rett Syndrome |
| PMC4072689__F5 | Hijacking of Host Cellular Functions by an Intracellular Parasite, the Microsporidian Anncaliia algerae |
| PMC4072696__F9 | Integrative Identification of Deregulated MiRNA/TF-Mediated Gene Regulatory Loops and Networks in Prostate Cancer |
| PMC4073101__F3 | Cilia and cilia-associated proteins in cancer |
| PMC4073278__F7 | The changes that are induced in cells by a deficiency of RPs |
| PMC4073476__F3 | Bile Acids are Nutrient Signaling Hormones |
| PMC4073605__F7 | Proposed model for the formation of reactive oxygen species at mitochondria, activation of Nrf2, and regulation of phase 2 gene expression in the nucleus |
| PMC4073609__F2 | By activating Sirt1, NAD+ conjoins two feedback loops necessary for cross-talk between the circadian clock and metabolite production |
| PMC4073990__F4 | Schematic description of the signaling pathways known to be activated by CCK1R and CCK2R |
| PMC4074033__F6 | Kaposi Sarcoma Herpes Virus Latency Associated Nuclear Antigen Protein Release the G2/M Cell Cycle Blocks by Modulating ATM/ATR Mediated Checkpoint Pathway |
| PMC4074185__F3 | Hereditary leiomyomatosis and renal cell carcinoma. |
| PMC4074217__F5 | Comparison of apoptotic pathways and NLRP3 inflammasome activation |
| PMC4074399__F1 | Cell Death Pathways |
| PMC4074489__F4 | p58IPK and UPR-associated inflammatory signaling pathways |
| PMC4074565__F1 | Regulation of mTORC1 by amino acids |
| PMC4074570__F3 | Regulation of receptor-mediated endocytosis by CRL pathways |
| PMC4074572__F1 | Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology |
| PMC4074825__F3 | FHIT-substrate complex as a signaling molecule |
| PMC4075038__F3 | Signal Transduction in Vasculogenesis and Developmental Angiogenesis |
| PMC4075065__F1 | Insulin/mTOR signaling pathway and also the extrinsic modifiers that are present in diabetes |
| PMC4075129__F1 | PI3K/AKT/GSK-3B signaling pathway in neuronal cells of Alzheimer's disease |
| PMC4075164__F2 | Multiple intracellular signal transduction pathways are activated by GH |
| PMC4075245__F1 | Simplified schema showing how genes might affect clinical responses to targeted therapies |
| PMC4075250__F5 | Ingenuity network analysis of differentially regulated labeled-pairs |
| PMC4075272__F2 | Signaling pathways altered by MVNP and mutant p62 |
| PMC4075356__F6 | An Irf6-dependent pathway regulating keratinocyte migration |
| PMC4075482__F5 | Pathway Analysis |
| PMC4076091__F7 | GW1516 intervention inhibits progression of hepatic steatosis in mice |
| PMC4076637__F6 | CDK4/6 is downstream of multiple pathways |
| PMC4076814__F6 | Diagram depicting the role of GPX7 in regulating inflammation in esophageal epithelial cells |
| PMC4076815__F1 | Typical PDA cell is depicted showing schematics of representative metabolic pathways that are altered in the disease in response to oncogenic Kras |
| PMC4076843__F2 | Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders |
| PMC4076960__F8 | Muscle hypertrophy and atrophy |
| PMC4076992__F2 | Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease |
| PMC4077447__F2 | 6-Thioguanine: A Drug With Unrealized Potential for Cancer Therapy |
| PMC4077471__F3 | Examples of pathway engineering and combinatorial biosynthesis to generate new analogs: A |
| PMC4077663__F2 | Leptin-brain melanocortin system interaction |
| PMC4077717__F1 | Overview of the general innate immune response to viral infection |
| PMC4077819__F5 | Inhibition of C3 Convertase Activity by Hepatitis C Virus as an Additional Lesion in the Regulation of Complement Components |
| PMC4077879__F1 | Selective autophagy against membranous compartments |
| PMC4077896__F1 | Autophagic structures in the regulation of MAPK phosphorylation |
| PMC4077897__F1 | Emerging potential of autophagy-based therapies in the treatment of cystic fibrosis lung infections |
| PMC4077930__F3 | mTORC2 in the center of cancer metabolic reprogramming |
| PMC4077945__F1 | Lipid metabolites as metabolic messengers in inter-organ communication |
| PMC4078227__F2 | Hedgehog signal pathway |
| PMC4078240__F4 | Map of SCAP/SREBP Transcriptional Control of Cholesterol and FA Biosynthesis |
| PMC4078307__F1 | Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival |
| PMC4079355__F8 | Flavonoid Biosynthesis and Regulatory Pathways |
| PMC4079587__F5 | Interaction of kisspeptin, estrogen and BMP-4 in regulation of GnRH production by GT1-7 cells |
| PMC4079737__F1 | Molecular Pathways: Niches in Metastatic Dormancy |
| PMC4080186__F1 | Rho GTPase signaling pathway represents a convergent approach to targeting fibrosis |
| PMC4080280__F4 | Stage-specific expression of individual genes in Ras and Wnt pathway orchestrate cardiogenesis |
| PMC4081080__F3 | miR-143/145 modulate signaling through the Ras-MAPK pathway |
| PMC4081601__F3 | Proposed mechanisms of anticancer activity of digoxin |
| PMC4081624__F1 | IGF signaling pathway |
| PMC4081668__F2 | Nuclear export of hepatitis B virus mRNAs |
| PMC4081675__F1 | Signaling pathways regulating hepatic stellate cell activation in alcoholic liver disease |
| PMC4081676__F1 | Protective role and partial mechanism of peroxisome proliferator-activated receptor A in alcoholic liver disease |
| PMC4081729__F5 | Modification of the Nrf-2 and NFKB signaling pathways by phytochemicals upregulates antioxidant and detoxification enzymes and suppresses inflammation |
| PMC4081859__F2a | Complement regulation of T cell immunity |
| PMC4082184__F2 | Turning Off AKT: PHLPP as a Drug Target |
| PMC4082763__F1 | Protein Prenylation and Synaptic Plasticity: Implications for Alzheimer's Disease |
| PMC4082789__F1 | Exploiting sulphur-carrier proteins from primary metabolism for 2-thiosugar biosynthesis |
| PMC4082998__F1 | Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes |
| PMC4083090__F7 | A model of the role for ATRIP SUMOylation in the ATR pathway |
| PMC4083453__F5 | The possible mechanisms of CRI enhancing insulin action and insulin signaling were shown in figure |
| PMC4083591__F1 | Type I Interferon in the Pathogenesis of Lupus |
| PMC408363__F1 | Complexity of the CD28/CD152-B7-1/B7-2 T-cell costimulatory pathway |
| PMC4083693__F1 | Wnt signaling is required for long-term memory formation |
| PMC4083752__F1 | Unexpected targets and triggers of autoimmunity |
| PMC4083841__F1a | Beta-Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis |
| PMC4083854__F2 | Diagram showing the effects of knockout or blockade of specific elements of the alternative, classical and lectin pathways of complement activation on the pathogenesis of anti-MPO induced murine crescentic glomerulonephritis |
| PMC4084431__F1 | Genes directly related to dopamine functioning |
| PMC4084493__F2 | Non-homologous end joining: emerging themes and unanswered questions |
| PMC4084552__F1 | IL-33/ST2 signaling pathway |
| PMC4084561__F2 | Regulation of type I interferon responses |
| PMC4084561__F3 | Regulation of type I interferon responses |
| PMC4084718__F4 | Contextualizing Sharpin within the NFKB pathway by comparative analysis of mutant transcriptomes |
| PMC4084821__F3 | Irinotecan Pathway, view of a model human liver cell showing blood, bile, and intestinal compartments, indicating tissue-specific involvement of genes in the irinotecan pathway |
| PMC4084917__F7 | Fatostatin Displays High Anti-Tumor Activity in Prostate Cancer by Blocking SREBP-Regulated Metabolic Pathways and Androgen Receptor Signaling |
| PMC4084927__F10 | Acetaminophen and NAPQI are Toxic to Auditory Cells via Oxidative and Endoplasmic Reticulum Stress-dependent Pathways |
| PMC4085163__F6 | Schematic models of signalling pathways used by SDF-1/CXCR4 and GLP-1/GLP-1R in the activation of beta catenin/TCF7L2-mediated transcriptional expression of genes involved in beta cell survival and proliferation a SDF-1 activation of WNT signalling |
| PMC4085325__F4 | SphK1/S1P/S1PR1 feed-forward loop sustain signals promoting colon tumorigenesis.Notes: SphK1 produces S1P, which is kept in the cell and/or is exported in the extracellular milieu |
| PMC4085347__F3 | Diagrammatic presentation of regulation of Keap1-Nrf2-ARE pathway |
| PMC4085347__F4 | A mechanism showing tyrosine kinase receptor induced regulation of Nrf2 nuclear-cytoplasmic shuttling under redox homeostasis conditions |
| PMC4085347__F5 | Schematic presentation of MRN complex recruitment towards radiation induced DNA damage foci |
| PMC4085491__F1 | ELF4 in type I IFN signaling |
| PMC4085546__F2 | KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma |
| PMC4085722__F2 | Regulation of protein trafficking, receptor signaling, and protein clearance by ubiquitination in Alzheimer's disease |
| PMC4085879__F2 | Targets in T-ALL: PI3K/AKT/mTOR, cyclin D3:CDK4/6, BRD4/MYC |
| PMC4085981__F1 | Positive feedback in cardioprotection: Can more mechanism lead to translation? |
| PMC4085993__F4 | Iron Homeostasis in Peripheral Nervous System, Still a Black Box? |
| PMC4086337__F1 | NLRP3 inflammasome regulates the caspase-1 dependent maturation and secretion of pro-inflammatory cytokines |
| PMC4086339__F5 | Deregulated focal adhesion pathway in NSCLC cell lines |
| PMC4086377__F1 | TGFB Signaling in Wound Epithelialization |
| PMC4086428__F3 | Three commonly differentially expression MicroRNAs in pancreatic cancer tissue and patient blood: MicroRNAs 21, 155, and 200 |
| PMC4086428__F4 | Predicted network linking pancreatic cancer miRNA markers, known pancreatic cancer genetic lesions, and DAMPs |
| PMC4086465__F1 | NKT-cell subsets: Promoters and protectors in inflammatory liver disease |
| PMC4086482__F1 | Phosphoinositide-3-kinase-Akt-mTOR pathway |
| PMC4086483__F1 | NFKB signaling pathway |
| PMC4086757__F1 | Classification of resistance mechanisms to BRAF inhibitors |
| PMC4086823__F1 | Stochasticity of Intranuclear Biochemical Reaction Processes Controls the Final Decision of Cell Fate Associated with DNA Damage |
| PMC4086823__F3 | Stochasticity of Intranuclear Biochemical Reaction Processes Controls the Final Decision of Cell Fate Associated with DNA Damage |
| PMC4087127__F2 | Scheme of ErbB dimers related MAPK and PI3K pathway activation |
| PMC4087161__F2 | Phosphorylation of Foxo1 at S253 by Akt promotes Foxo1 cytoplasmic retention and ubiquitination, which serves as a central mechanism controlling Foxo1 stability and activity () |
| PMC4087218__F4 | Resveratrol on protein phosphorylation in the insulin signaling pathway and the mTOR pathway of obese mice |
| PMC4087507__F1 | NOD2/TLR4 signaling pathway |
| PMC4087671__F1 | Control of the TRAF6 signalosome by miR-146a |
| PMC4087737__F1 | A: The heme biosynthetic pathway |
| PMC4088370__F2 | KEGG MAPK signalling pathway |
| PMC4088370__F3 | KEGG Cell-cycle pathway |
| PMC4088370__F4 | KEGG Apoptosis pathway |
| PMC4088925__F3 | Summary of expression patterns of complement components in the placenta |
| PMC4088997__F5 | Rapamycin and paclitaxel nanoparticles synergistically target the PI3K/Akt/mTOR pathway by suppressing feedback loop Akt phosphorylation |
| PMC4089092__F1 | Toll-like receptor (TLR) signaling pathway |
| PMC4089153__F1 | Sooner and later |
| PMC4089392__F1 | Toward the development of podocyte-specific drugs |
| PMC4089452__F2 | Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease |
| PMC4089598__F2 | Regulatory T cells and co-stimulatory pathways |
| PMC4089899__F3 | Future directions for the management of pain in osteoarthritis |
| PMC4090103__F2 | Virulence Strategies of the Dominant USA300 Lineage of Community Associated Methicillin Resistant Staphylococcus aureus (CA-MRSA) |
| PMC4090148__F11 | Evidence that RASSF1C Stimulation of Lung Cancer Cell Proliferation Depends on IGFBP-5 and PIWIL1 Expression Levels |
| PMC4090290__F1 | Epidermal growth factor receptor (EGFR) pathway activation during HNSCC carcinogenic process |
| PMC4090390__F2 | Metabolic fluxes, NLRP3 and IL-1B |
| PMC4090493__F6 | Proposed mechanism by which [6]-shogaol inhibits melanin biosynthesis |
| PMC4090694__F1 | ADAM10 Prodomain Mutations Cause Late-Onset Alzheimer's Disease: Not Just the Latest FAD |
| PMC4090903__F2 | TLR4 intracellular signaling cascade |
| PMC4091098__F1 | Heat shock protein-CD91 pathway mediates tumor immunosurveillance |
| PMC4091179__F10 | Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells |
| PMC4091181__F10 | The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells |
| PMC4091318__F5 | The LNK1 night light-inducible and clock-regulated gene is induced also in response to warm-night through the circadian clock nighttime repressor in Arabidopsis thaliana. |
| PMC4091319__F1 | Transcription factors involved in brassinosteroid repressed gene expression and their regulation by BIN2 kinase |
| PMC4091570__F1 | Interplay of transcription factors in suppression of UV-B induced flavonol accumulation by flg22 |
| PMC4091682__F1 | EGFR/PI3K Pathway |
| PMC4091735__F1 | Evading apoptosis in cancer |
| PMC4091760__F2 | Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1A signaling node |
| PMC4091806__F1 | A New Lnc in Metastasis: Long Non-Coding RNA Mediates the Pro-metastatic Functions of TGFB |
| PMC4091817__F2 | The oxidative stress regulatory pathway in erythrocytes |
| PMC4091980__F1 | Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain |
| PMC4092039__F1 | G-Protein Coupled Receptors Engage the Mammalian Hippo pathway through F-Actin |
| PMC4092039__F2 | G-Protein Coupled Receptors Engage the Mammalian Hippo pathway through F-Actin |
| PMC4092085__F2 | Na+, K+-ATPase-mediated signal transduction |
| PMC4092141__F1 | cGMP and NHR Signaling Co-regulate Expression of Insulin-Like Peptides and Developmental Activation of Infective Larvae in Strongyloides stercoralis |
| PMC4092857__F3 | Activation of the DNA damage response upon CDT exposure |
| PMC4092924__F2 | Schematic illustration of the current working hypothesis on IFNT signaling in ovine uterine stroma and uterine glandular epithelium compared to uterine luminal (LE) and supferficial glandular (sGE) epithelia |
| PMC4092924__F3 | Proposed model of IFNT signal transduction cascades that is independent of STAT1 in the ovine uterine LE and sGE |
| PMC4093113__F2 | Pathway analysis of the candidate genes |
| PMC4094071__F8 | AEG-1 regulation of HIV-1 neuropathogenesis |
| PMC4094296__F3 | Pathogenetic Importance and Therapeutic Implications of NFKB in Lymphoid Malignancies |
| PMC4094593__F9 | Diagram of the roles of miR-206 in hepatocellular carcinoma (HCC) HepG2 cells |
| PMC4094786__F4 | Metabolic pathways for the production of the high-value products by using Z |
| PMC4095017__F2 | Signaling and cross talk of the parathyroid hormone and Wnt signaling pathways in the late osteoblast (osteocyte) |
| PMC4095565__F2 | NOD1 and NOD2 signaling cascades |
| PMC4095756__F2a | GRK2 - A Link Between Myocardial Contractile Function and Cardiac Metabolism |
| PMC4095764__F1 | Physiological anticoagulant characteristics of blood vessels on endothelial cells |
| PMC4095859__F3 | Metabolic requirements for the maintenance of self-renewing stem cells |
| PMC4095906__F3 | TLR and BCR signaling and integration in CSR and antibody responses |
| PMC4096053__F2 | Many functions of promyelocytic leukemia nuclear bodies and PML as a negative regulator of the PI3-kinase/Akt/mTOR pathway |
| PMC4096159__F2 | Emerging Role of Autophagy in Alcoholic Liver Disease |
| PMC4096794__F8 | Sumoylation Pathway Is Required to Maintain the Basal Breast Cancer Subtype |
| PMC4097023__F6 | Working model of apigenin-induced DNA damage |
| PMC4097318__F1a | Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis |
| PMC4097927__F4 | Polyamidoamine dendrimer-based gene delivery vectors |
| PMC4097957__F1 | TLR4 signaling pathway |
| PMC4098112__F1 | Regulation of muscle mass |
| PMC4098619__F1 | Schematic diagram representation of some of the pathways regulated by HNF1a |
| PMC4098898__F2 | Glutamate Metabolism and HIV-Associated Neurocognitive Disorders |
| PMC409892__F2 | Apoptotic and antiapoptotic signaling pathways |
| PMC4098942__F3 | Cancer model pathway |
| PMC4099115__F3 | Metscape gene-compounds metabolic network views of top IPA canonical pathway and biological function/disease |
| PMC4099115__F4 | IPA metabolic interaction network of plasma metabolites having a significant correlation with polyp counts in association with aGenotypebyDietinteraction effect |
| PMC4099309__F2 | TNF and MAP kinase signaling pathways |
| PMC4099309__F3 | TNF and MAP kinase signaling pathways |
| PMC4099360__F1 | Toll-like receptor 4 and hepatic fibrogenesis |
| PMC4099420__F6 | Gene Expression Profiling of the Response to Interferon Beta in Epstein-Barr-Transformed and Primary B Cells of Patients with Multiple Sclerosis |
| PMC4100108__F4 | The possible regulatory pathway of melanogesis activation |
| PMC4100111__F3 | Bioinformatics analysis by String |
| PMC4100138__F2 | Autophagic cell death in lung tumor cells |
| PMC4100143__F1 | Diagram of CD4 T cell differentiation and immunomodulation by the AhR signaling pathway |
| PMC4100211__F1 | Proposed frame work for mRNA nanoparticle mediated tumour vaccination |
| PMC4100379__F5 | The proposed mechanism underlying the inhibitory effect of MLN4924 in prostate cancer cells |
| PMC4100437__F1 | Hypothetical model of chemoresistance in human ovarian cancer cells |
| PMC4100540__F9 | Role of PTEN in PI3K/AKT/mTOR signaling and cell proliferation following growth factor binding to its receptor |
| PMC4100983__F4 | Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer |
| PMC4101819__F1 | Key signaling pathways involved in genetic methylation of lymphoid malignancies |
| PMC4101832__F2 | Processes and outcomes involving leptin, OB-R, Notch1, Notch4, IL-1R tI, JAG1, DLL4, VEGF, VEGFR2 (KDR), EGFR, AR and Ki67 (MKi67 gene) in the development of breast neoplasms |
| PMC4101967__F2 | Interference with type I IFN-activated JAK/STAT signaling pathway and antiviral ISGs |
| PMC4102070__F2 | Signal integration following BCR engagement |
| PMC4102070__F4 | Points of inhibition for ibrutinib, idelalisib, fostamatinib, and Lck-i in the BCR signaling pathway |
| PMC4102378__F2 | WNT signaling pathway |
| PMC4102553__F4 | Serum Metabolomic Response of Myasthenia Gravis Patients to Chronic Prednisone Treatment |
| PMC4102648__F2 | UV signaling pathways within the skin |
| PMC4102744__F1 | Cytoplasmic/traditional and nuclear modes of the epidermal growth factor receptor (EGFR) signalling pathway |
| PMC4102778__F3 | GSK-3 as potential target for therapeutic intervention in cancer |
| PMC4102778__F7 | GSK-3 as potential target for therapeutic intervention in cancer |
| PMC4102824__F1 | Flow diagram of the monoamine neurotransmitter biosynthesis pathway |
| PMC4103158__F3 | Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns |
| PMC4103658__F7 | GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst. |
| PMC4103865__F2 | Integrating Genomics and Proteomics Data to Predict Drug Effects Using Binary Linear Programming |
| PMC4104069__F2 | Pathways to Tumorigenesis and Persistent Infection. |
| PMC4104073__F2 | Splicing regulation of the androgen receptor (AR) and phosphoinositide 3-kinase (PI3K) signaling pathways |
| PMC4104311__F2 | Small System–High-Resolution Study of Metabolic Adaptation in the Central Metabolic Pathway to Temperate Climates in Drosophila melanogaster |
| PMC4104414__F1 | Figure shows the endothelial response to a high salt diet |
| PMC4104445__F1 | Life in the bile duct. |
| PMC4104512__F4 | Functional zonation of the rat adrenal cortex: the development and maintenance |
| PMC4104517__F2 | Cell Death and Survival Through the Endoplasmic Reticulum-Mitochondrial Axis |
| PMC4104550__F1 | ALK signaling pathway with its cross-talk with other pathways involved in the resistance to ALK-inhibitors |
| PMC4104784__F5 | RNA-seq upregulation of energy metabolism gene expression |
| PMC4105198__F8 | B3 integrin-KRAS-RalB complex drives tumor stemness and resistance to EGFR inhibition |
| PMC4105535__F4 | Molecular Changes in Pre-Metastatic Lymph Nodes of Esophageal Cancer Patients |
| PMC4105632__F1 | Nigrostriatal, mesocortical, and mesolimbic pathways |
| PMC4105941__F1 | The Self-Limiting Dynamics of TGFB Signaling In Silico and In Vitro, with Negative Feedback through PPM1A Upregulation |
| PMC4105970__F5 | Schematic model of specific KDAC targeting through pharmaco-logic modulation of its regulatory pathway |
| PMC4106090__F1 | N-glycosylation pathway |
| PMC4106090__F3 | GPI anchorage pathway |
| PMC4106164__F1 | PD-L1 expression and tumor-infiltrating lymphocytes |
| PMC4106326__F15 | Model depicting how PPARB/D promotes H-RAS-induced cellular senescence, whereas ER stress attenuates H-RAS-induced cellular senescence |
| PMC4106421__F2 | ARF impinges both on developmental processes (male germ cell development and ocular development in mice) and tumor angiogenesis |
| PMC4106657__F4 | Cancer driver genes and pathways |
| PMC4106758__F6 | Visualized Gene Network Reveals the Novel Target Transcripts Sox2 and Pax6 of Neuronal Development in Trans-Placental Exposure to Bisphenol A |
| PMC4107035__F2 | PATHOGENETIC MECHANISMS OF FOCAL CORTICAL DYSPLASIA |
| PMC4107035__F3 | PATHOGENETIC MECHANISMS OF FOCAL CORTICAL DYSPLASIA |
| PMC4107064__F1 | Progress in Central Nervous System Lymphomas |
| PMC4107103__F6 | Hypothetical model of molecular determinants of CLL cell survival, proliferation and migration in the PB, BM and LN microenvironments |
| PMC4107204__F1 | Chalcones with minor structural changes result in distinct processes of cell death |
| PMC4107230__F6 | Different mechanisms of signaling for EMT which might be induced by FGF10 |
| PMC4107319__F8 | GIV/Girdin is a central hub for pro-fibrogenic signalling networks during liver fibrosis |
| PMC4107453__F8 | Role of the SIK2-p35-PJA2 complex in pancreatic beta cell functional compensation |
| PMC4107458__F1 | Neutrophil derived S100a8/S100a9 protein potentially contributing hypertensive cardiac fibrosis induced by Ang II |
| PMC4107712__F1 | Illustration of the PI3K/Akt/mTOR pathway |
| PMC4107774__F1 | The Hippo signalling core cassette in mammals |
| PMC4107940__F1 | General interplay between the canonical TLR signaling pathway, the cytokine-mediated DNA repair feedback loop, and the growth factors-mediated signaling pathway |
| PMC4107945__F1 | RLR signaling pathway is shown |
| PMC4107957__F1 | Toll-like receptors and TLR-mediated signaling pathway |
| PMC4107983__F1 | Transcriptional programs controlling endocytosis |
| PMC4108232__F1 | Mitochondrial dysfunctions in cancer |
| PMC4108799__F3 | HMGB1 binding to receptors and activating signal transduction pathway |
| PMC4108926__F2 | Melanoma and integrated Breast cancer pathway landscape |
| PMC4109581__F2 | Necroptosis and pyroptosis both lead to the loss of cell membrane integrity |
| PMC4109688__F2 | Toward T Cell Protein-Protein Interaction Activity Relevant to Alopecia Areata |
| PMC4109802__F2 | Fibroblast growth factor-2 signaling in neurogenesis and neurodegeneration |
| PMC4110034__F1 | Microbial Egress: A Hitchhiker's Guide to Freedom |
| PMC4110160__F1 | Differential LSEC Signalling in Models of Acute or Chronic Injury |
| PMC4110175__F2 | SP600125 and BCI Inhibition in MAPK Signaling Pathway adapted from KEGG 04010 |
| PMC4110175__F5 | LDN Inhibition in TGFB Signaling Pathway adapted from KEGG 04350 |
| PMC4110182__F1 | SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease |
| PMC4110478__F1 | Hypoxia inducible factor and VEGF link the HIF/VHL and PI3K/Akt/mTOR signaling pathways |
| PMC4110479__F2 | Proinflammatory properties of plasmacytoid dendritic cells (pDCs) |
| PMC4110479__F3 | Tolerogenic properties of plasmacytoid dendritic cells (pDCs) |
| PMC4110518__F1 | Cellular origin of thyroid carcinomas is shown |
| PMC4110625__F1 | Model of ER stress-associated inflammation |
| PMC4110655__F2 | Proposed mechanism of action of the erythroid regulator ERFE |
| PMC4110660__F2 | In silico network and pathway enrichment analysis |
| PMC4110715__F5 | GeneGo graphic representation illustrates Transcription Androgen Receptor (AR) nuclear signaling |
| PMC4111284__F1 | IGF signaling pathway |
| PMC4111689__F1 | Targeting the Achilles' heel of drug-resistant cancer stem cells |
| PMC4111749__F2 | Regulation and roles of Cdc7 kinase under replication stress |
| PMC4111847__F4 | Glycolysis and the triacylglycerol biosynthetic pathway in Cp0710 |
| PMC4111852__F3 | PI3K pathway in different breast cancer subtypes |
| PMC4111858__F5 | Two-step model for OR-instructed axonal projection of OSNs |
