| Description | Sets of genes/proteins extracted from pathway figures in research publications using optical character recognition, updated for 2024 |
| Measurement | association by literature curation |
| Association | protein-pathway associations extracted from figures in published literature |
| Category | structural or functional annotations |
| Resource | Pathway Figure Optical Character Recognition |
| Citation(s) | |
| Last Updated | 2024 Sep 24 |
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Gene Attribute
Gene Similarity
Attribute Similarity
UMAP
54337 sets of proteins participating in pathways from the Wikipathways PFOCR 2024 dataset.
| Gene Set | Description |
|---|---|
| PMC100005__F11 | Formation of TrkA-src-aPKC complexes |
| PMC10003241__F3 | Metabolic Features of Osteoblasts: Implications for Multiple Myeloma (MM) Bone Disease |
| PMC10025411__F1 | Neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and neuroinflammation |
| PMC10028837__F1 | The oxidative phase of the pentose phosphate pathway including 6-phosphogluconolactonase (Pgl), that converts 6-P-gluconololactone to gluconate-6-P |
| PMC10030510__F2 | Metabolic regulation of dendritic cell activation and immune function during inflammation |
| PMC10030510__F4 | Metabolic regulation of dendritic cell activation and immune function during inflammation |
| PMC10030580__F2 | Macrophages in aseptic loosening: Characteristics, functions, and mechanisms |
| PMC10030587__F2 | Key events in cancer: Dysregulation of SREBPs |
| PMC10030840__F2 | Genetic analyses of DNA repair pathway associated genes implicate new candidate cancer predisposing genes in ancestrally defined ovarian cancer cases |
| PMC10030845__F1 | Inflammasome and pyroptosis in autoimmune liver diseases |
| PMC10030845__F2 | Inflammasome and pyroptosis in autoimmune liver diseases |
| PMC10031043__F1 | Maintenance of genome integrity by the late-acting cytoplasmic iron-sulfur assembly (CIA) complex |
| PMC10031108__F9 | Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway |
| PMC10031116__F5 | Extracellular matrix stiffness—The central cue for skin fibrosis |
| PMC10031116__F6 | Extracellular matrix stiffness—The central cue for skin fibrosis |
| PMC10031257__F3 | Focal adhesion proteins in skeleton and diseases |
| PMC10033548__F7 | SFRP1 induces a stem cell phenotype in prostate cancer cells |
| PMC10033682__F3 | Ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway |
| PMC10033682__F4 | Ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway |
| PMC10033690__F1 | Sex-differences in prostaglandin signaling: a semi-systematic review and characterization of PTGDS expression in human sensory neurons |
| PMC10034053__F2 | Immune cells and immune cell-targeted therapy in chronic pancreatitis |
| PMC10034056__F1 | Effect of Bifidobacterium on osteoclasts: TNFA/NFKB inflammatory signal pathway-mediated mechanism |
| PMC10034056__F2 | Effect of Bifidobacterium on osteoclasts: TNFA/NFKB inflammatory signal pathway-mediated mechanism |
| PMC10034899__F1 | Sirtuins in attenuating plaque vulnerability in atherosclerosis |
| PMC10035050__F6 | Sodium acetate regulates milk fat synthesis through the activation of GPR41/GPR43 signaling pathway |
| PMC10035551__F1 | Regulation of PD-1 and PD-L1 expression in sepsis |
| PMC10035756__F5 | State-of-the-art therapeutic strategies for targeting cancer stem cells in prostate cancer |
| PMC10035973__F6 | RNA-seq and microRNA association analysis to explore the pathogenic mechanism of DHAV-1 infection with DEHs |
| PMC10036181__F4 | Molecular and Cellular Crosstalk between Bone and Brain: Accessing Bidirectional Neural and Musculoskeletal Signaling during Aging and Disease |
| PMC10036296__F1 | An Evolving Understanding of the Basis and Management of Vascular Complications of COVID-19: Where Do We Go From Here? |
| PMC10036500__AF1 | MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335–5p signaling pathway |
| PMC10036590__F4 | Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications |
| PMC10036653__F8 | ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival |
| PMC10036758__F1 | The complosome in health and disease |
| PMC10037167__F1 | Myostatin silencing inhibits podocyte apoptosis in membranous nephropathy through Smad3/PKA/NOX4 signaling pathway |
| PMC10037252__F2 | Systemic treatment for metastatic colorectal cancer |
| PMC10037406__F1 | CGAS-STING signaling pathway |
| PMC10037406__F5 | Posttranslational modification in the cGAS-STING pathway |
| PMC10037512__F6 | Mechanism of STX5 involvement in HCC metastasis |
| PMC10037588__F6 | Reassessing the Abundance of miRNAs in the Human Pancreas and Rodent Cell Lines and Its Implication |
| PMC10037657__F1 | Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer |
| PMC10037657__F2 | Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer |
| PMC10037657__F3 | Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer |
| PMC10037992__F4 | Fasting: From Physiology to Pathology |
| PMC10038327__F3 | Mitochondria as disease-relevant organelles in rheumatoid arthritis |
| PMC10038327__F4 | Mitochondria as disease-relevant organelles in rheumatoid arthritis |
| PMC10039534__F2 | Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment |
| PMC10039784__F1 | Deficient radiation transcription response in COVID-19 patients |
| PMC10040131__F7 | PHF6 recruits BPTF to promote HIF-dependent pathway and progression in YAP-high breast cancer |
| PMC10040407__F8 | Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure |
| PMC10040548__F5 | Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis |
| PMC10040548__F6 | Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis |
| PMC10040549__F1 | Ferroptosis in non-alcoholic liver disease: Molecular mechanisms and therapeutic implications |
| PMC10040566__F2 | Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target |
| PMC10040566__F3 | Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target |
| PMC10040598__F1 | The inflammasome in insulin resistance and type 2 diabetes mellitus |
| PMC10040775__F5 | Low-protein maternal diet during gestation affects the expression of key pancreatic Beta-cell genes and the methylation status of the regulatory region of the MafA gene in the offspring of Wistar rats |
| PMC10040812__F8 | Signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet B cells in response to high glucose |
| PMC10040851__F6 | Single-cell atlas reveals shared and distinct immune responses and metabolic profiles in SARS-CoV-2 and HIV-1 infections |
| PMC10041388__F1 | Metabolic reprogramming in cancer: Mechanisms and therapeutics |
| PMC10041467__F1 | Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer’s Disease |
| PMC10041467__F11 | Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer’s Disease |
| PMC10041518__F1 | Biosynthetic pathways for pyrimidine and purine nucleotides, relevant inhibitors and oncogenic regulators |
| PMC10041518__F2 | Nucleotides fuel cancer cell growth and proliferation |
| PMC10041518__F3 | Altered nucleoside handling facilitates cancer cell immune evasion |
| PMC10041518__F4 | Supraphysiological GTP abundance promotes metastasis through the activation of RHO-family GTPases |
| PMC10041518__F5 | Hyperactive nucleotide synthesis confers resistance to a range of therapeutic interventions |
| PMC10041561__F15 | Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs |
| PMC10041561__F17 | Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs |
| PMC10041595__F5 | NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis |
| PMC10042294__F7 | Dark side of mRNA translation and the translation machinery in glioblastoma |
| PMC10055176__F8 | Changes in Environmental Stress over COVID-19 Pandemic Likely Contributed to Failure to Replicate Adiposity Phenotype Associated with Krtcap3 |
| PMC10085880__F7 | In silico identification of potential miRNAs -mRNA inflammatory networks implicated in the pathogenesis of COVID-19 |
| PMC10088895__F1 | PD-1/PD-L1 pathway plays a role in immunosuppression |
| PMC10093079__F5 | Baicalein in regulating the cancer signaling pathways |
| PMC10093079__F7 | Baicalein inhibits cancer cell progression by targeting P13K/FOXO pathways |
| PMC10093344__F1 | Innate immune signaling pathway that recognizes cytosolic DNA in tumor-infiltrating dendritic cells (TIDCs) |
| PMC10093344__F3 | Tumor immunosuppressive mechanism of AIM2 in TIDCs |
| PMC10094755__F6 | Metabolic pathway of 17Beta-estradiol biosynthesis |
| PMC10095454__F6 | The mechanism by which SDC3 cooperates with the regulation of milk fat synthesis and inflammatory response |
| PMC10095465__F1 | Apoptotic signaling pathway |
| PMC10095594__F1 | Canonical Wnt signaling pathway |
| PMC10100231__F7 | Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGFB1 signaling |
| PMC10121351__F8 | Schematic of the molecular mechanism underlying UA anticancer activity in NSCLC cells |
| PMC10121353__F8 | Main nodes of AGE-RAGE signaling pathway |
| PMC101242__F7 | Up-regulation of RAD51 in 8-MOP-treated cells |
| PMC10124776__F1 | Pig heart and lung xenotransplantation: Present status |
| PMC10125773__F3 | IL-1A and IL-1B synthesis and signal transduction pathways |
| PMC10125773__F5 | TNFA signalling pathway |
| PMC10131518__F2 | Primary and Secondary micro-RNA Modulation the Extrinsic Pathway of Apoptosis in Hepatocellular Carcinoma |
| PMC10135105__F3 | Activation of NRF2 signaling pathway by 4-HNE |
| PMC10135467__F2 | Illustration of the regulatory network of METTL3 in the nervous system |
| PMC10135714__F10 | Schematic illustration shows the protective effect of extract of Lonicera japonica in particulate-matter (PM)2 |
| PMC10135819__F2 | Diagram illustrating RET and RET-regulated NAD+-dependent sirtuin signaling pathway as a contributor and potential therapeutic target for aging, age-related diseases, and ischemic stroke |
| PMC10135928__F7 | Lipid synthesis in adipocyte differentiation and functions |
| PMC10136030__F1 | Structure and functions of telomeres |
| PMC10136030__F2 | Classification of BCL-2 family proteins and their role in the regulation of the internal pathway of apoptosis |
| PMC10136030__F3 | TERT is involved in major signaling pathways and participates in regulation of gene expression |
| PMC10136030__F4 | In the nucleus, TERT performs both canonical (elongates telomeric ends) and non-canonical functions (participates in the regulation of gene expression) |
| PMC10136283__F7 | KEGG pathway map for Wnt signaling pathway |
| PMC10136307__F2 | Inhibition and induction of autophagy |
| PMC10136307__F4 | Proposed ER-related mechanisms in the induction of autophagy and UPR in B cells |
| PMC10136495__F2 | TGFB signaling pathway in LC development and metastasis |
| PMC10136495__F3 | Targeting TGFB signaling pathway in LC |
| PMC10136533__F2 | Regulatory network of OTUD5 in immune response and DNA damage repair |
| PMC10136533__F3 | OTUD5 is involved in the development of cancer (see also Table 1) |
| PMC10136584__F1 | WNT signaling pathways |
| PMC10136628__F1 | Metabolic pathway of tetrahydrobiopterin (BH4) |
| PMC10136831__F1 | Biosynthesis of prostaglandins |
| PMC10136831__F3 | Crosstalk between PGE2 and EGFR |
| PMC10136857__F1 | Canonical and non-canonical Wnt signaling pathways in cholangiocytes and the role of the primary cilia in modulating these pathways |
| PMC10136927__F3 | Targeting Wnt signaling pathway by the latest technologies |
| PMC10136970__F3 | Pan-pathway inhibition |
| PMC10137108__F1 | Contribution of various long non-coding RNAs and microRNAs in osteogenic pathways |
| PMC10137108__F2 | Bone formation by miRNAs |
| PMC10137108__F3 | Long non-coding RNA that regulates osteosarcoma invasion and metastasis |
| PMC10137169__F1 | One Carbon Metabolism and S-Adenosylmethionine in Non-Alcoholic Fatty Liver Disease Pathogenesis and Subtypes |
| PMC10137218__F4 | WNK kinases regulate HCO3− versus Cl− secretion across human airway epithelia |
| PMC10137236__F1 | TGFB signaling pathway |
| PMC10137309__F1 | Extravasation steps in breast cancer brain metastasis |
| PMC10137309__F2 | Extravasation steps in melanoma brain metastasis |
| PMC10137309__F3 | Extravasation steps in lung cancer brain metastasis |
| PMC10137494__F2 | Steroid synthesis pathway |
| PMC10137601__F7 | Working model illustrating the mechanism that underlies the role of RA in regulating LH-induced oocyte meiotic resumption |
| PMC10137778__F8 | Whole Transcriptome Analysis of Differentially Expressed Genes in Cultured Nile Tilapia (O. niloticus) Subjected to Chronic Stress Reveals Signaling Pathways Associated with Depressed Growth |
| PMC10137778__F9 | Whole Transcriptome Analysis of Differentially Expressed Genes in Cultured Nile Tilapia (O. niloticus) Subjected to Chronic Stress Reveals Signaling Pathways Associated with Depressed Growth |
| PMC10138370__F6 | GCN2/eIF2A/ATF4 Pathway in the Liver and Induction of FGF21 in Young Goats Fed a Protein- and/or Phosphorus-Reduced Diet |
| PMC10138520__F2 | Compounds secreted by adipocytes support tumor growth, angiogenesis and metastasis |
| PMC10138520__F3 | Glycolysis and its relationship with other metabolic pathways in TNBC |
| PMC10138520__F5 | Lipid metabolic reprogramming in TNBC |
| PMC10138595__F1 | Cytokine Storm and ALI/ARDS Induced by Influenza Virus Infection |
| PMC10138595__F3 | PGE2 Promotes Immunoregulation through Cross-Regulation between Beta-catenin and NFKB by Activating the Wnt-Beta-catenin Signaling Pathways |
| PMC10138623__F6 | TLR4–RAGE crosstalk participates in the HG-enhanced LPS-induced inflammation in BAMs (created with BioRender |
| PMC10138709__F2 | Hedgehog signalling pathway |
| PMC10138709__F3 | Canonical and non-canonical Wnt signalling |
| PMC10138709__F5 | Hippo pathway and its crosstalk with other signalling pathways |
| PMC10138803__F7 | MicroRNA-146b-5p Suppresses Pro-Inflammatory Mediator Synthesis via Targeting TRAF6, IRAK1, and RELA in Lipopolysaccharide-Stimulated Human Dental Pulp Cells |
| PMC10138871__F7 | NpPP2-B10, an F-Box-Nictaba Gene, Promotes Plant Growth and Resistance to Black Shank Disease Incited by Phytophthora nicotianae in Nicotiana tabacum |
| PMC10138908__F7 | Which OBHS remodels abnormal glycometabolism, referring the experiment results |
| PMC10138955__F5 | Comparative Genomic Analysis of a Methylorubrum rhodesianum MB200 Isolated from Biogas Digesters Provided New Insights into the Carbon Metabolism of Methylotrophic Bacteria |
| PMC10139027__F5 | Scheme of LDLR activity signaling pathway for follicular development with lovastatin stimulates steroidogenesis in ovaries |
| PMC10139073__F2 | S1PR function in osteogenic cells |
| PMC10139073__F3 | Ying and Yang of Sphingosine-1-Phosphate Signalling within the Bone |
| PMC10139088__F5 | Metabolic plasticity regulation on tumour microenvironment |
| PMC10139088__F6 | Metabolic regulation on tumour metastasis |
| PMC10139189__F1 | Migration and invasion of GBM cells is related to the inherent capacity and the cellular interactions that occur on the migratory front |
| PMC10140933__F12 | Pathways of protein synthesis and transport activated by CsRALF34 overexpression (based on the KEGG signal pathway database) |
| PMC10140937__F4 | Mitochondrial DNA Supplementation of Oocytes Has Downstream Effects on the Transcriptional Profiles of Sus scrofa Adult Tissues with High mtDNA Copy Number |
| PMC10140952__F4 | Selected molecular targets of resveratrol |
| PMC10141502__F1 | Nutrigenomic profiling of reduced specification diets and phytogenic inclusion effects on critical toll-like receptor signaling, mitogen-activated protein kinase-apoptosis, and PI3K-Akt-mTOR gene components along the broiler gut |
| PMC10141515__F5 | Differentially expressed proteins of the glutamine metabolic pathway in ovarian cancer |
| PMC10141515__F6 | Differentially expressed proteins of the serine metabolic pathway in ovarian cancer |
| PMC10141597__F1 | Profiling Germinal Center-like B Cell Responses to Conjugate Vaccines Using Synthetic Immune Organoids |
| PMC10142234__F1 | Graphical representation of JAK-STAT signaling pathway and therapeutic compounds suppressing it through the inhibition of one or several members of the family |
| PMC10142331__F1 | Mechanisms by which SFTS inhibits key immune signalling pathways and promotes inflammation |
| PMC10142331__F2 | SFTSV mediates cell cycle, apoptosis, and the cGAS-STING pathway to achieve immune escape |
| PMC10142983__F6 | Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2 |
| PMC10143138__F2 | Osteoblast cellular cholesterol homeostasis |
| PMC10143456__F7 | Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease |
| PMC10143509__F3 | Involvement of p53 in activation of interferon genes, of interferon-stimulated genes, and in feedback loops regulating these processes |
| PMC10143579__F1 | Brain Kynurenine Pathway Metabolite Levels May Reflect Extent of Neuroinflammation in ALS, FTD and Early Onset AD |
| PMC10144233__F1 | Heme b biosynthesis pathway |
| PMC10144233__F2 | Formation of uroporphyrinogen III (UPG III) and the branching of the heme b biosynthesis |
| PMC10144535__F7 | Classical MAPK signaling pathway altered by 15 μM 7KCh treatment in mRPE cells and reversion effect exerted by 10 μM SA over this modulation |
| PMC10145126__F2 | PD-L1 regulation by IFNG |
| PMC10145673__F1 | G-protein-coupled receptor (GPCR) signaling pathway |
| PMC10145673__F2 | Molecular pathways involved in pituitary tumorigenesis |
| PMC10145676__F1 | Main metabolic pathways related to myo-inositol transformation inside the cell |
| PMC10147314__F2 | NEDD8 regulates the ubiquitin-proteasome degradation pathways related to CRL and MDM2, and it realizes the regulation of proteins by promoting the NFKB, PI3K/AKT/mTOR, Hippo-YAP and receptor tyrosine kinase signaling pathways |
| PMC10147314__F3 | Several signaling pathways are closely related to NEDD8 |
| PMC10147314__F4 | Several signaling pathways are closely related to NEDD8 |
| PMC10147314__F5 | NAE inhibitor MLN4924 has utility in the treatment of lung cancer |
| PMC10148080__F4 | NAT10 as ac4C writer in diseases |
| PMC10148099__F7 | Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease |
| PMC10148646__F1 | Molecular and Clinical Features of Hepatocellular Carcinoma in Patients with HBV-HDV Infection |
| PMC10149254__F5 | Chemical composition of pigeon crop milk and factors affecting its production: a review |
| PMC10149902__F12 | Endothelial METRNL determines circulating METRNL level and maintains endothelial function against atherosclerosis |
| PMC10149906__F1 | Building on the backbone of CD47-based therapy in cancer: Combination strategies, mechanisms, and future perspectives |
| PMC10149907__F5 | Regulatory mechanisms and inhibitors of isocitrate dehydrogenase 1 in cancer |
| PMC10149931__F9 | Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction |
| PMC10149936__F14 | Cofilin activation in pancreatic acinar cells plays a pivotal convergent role for mediating CCK-stimulated enzyme secretion and growth |
| PMC10149954__F2 | Receptors that bind to PEDF and their therapeutic roles in retinal diseases |
| PMC10149994__F1 | Reprogramming viral immune evasion for a rational design of next-generation vaccines for RNA viruses |
| PMC10150004__F1 | Infection routes, invasion mechanisms, and drug inhibition pathways of human coronaviruses on the nervous system |
| PMC10150162__F9 | Progress in non-viral localized delivery of siRNA therapeutics for pulmonary diseases |
| PMC10150574__F3 | Signaling through the phosphatidylinositol 3-kinase (PI3K)/AKT pathway |
| PMC10150895__F2 | Emerging role of long non-coding RNA JPX in malignant processes and potential applications in cancers |
| PMC10151263__F8 | Grain-sized moxibustion at Zusanli (ST36) promotes hepatic autophagy in rats with hyperlipidemia by regulating the ULK1 and TFEB expression through the AMPK/mTOR signaling pathway |
| PMC10151377__F3 | Insights into the pharmacological and therapeutic effects of apigenin in liver injuries and diseases |
| PMC10151533__F2 | Developmental origin of tendon diversity in Drosophila melanogaster |
| PMC10151556__F1 | An update on the role of thioredoxin-interacting protein in diabetic kidney disease: A mini review |
| PMC10151763__F1 | Klotho’s impact on diabetic nephropathy and its emerging connection to diabetic retinopathy |
| PMC10151763__F2 | Klotho’s impact on diabetic nephropathy and its emerging connection to diabetic retinopathy |
| PMC10151765__F2 | Generation, activation, and polarization of monocyte-derived macrophages in human malignancies |
| PMC10151830__F7 | Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy |
| PMC10152377__F1 | Somatic Variants Activating Ras/Raf/Mitogen-Activated Protein Kinase (MAPK) Pathway Genes in Mesial Temporal Lobe Epilepsy |
| PMC10152446__F7 | Structure Elucidation and Biosynthesis of Nannosterols A and B, Myxobacterial Sterols from Nannocystis sp. MNa10993 |
| PMC10152798__F5 | HDAC inhibitors on neuroblastoma SH-SY5Y cell differentiation into mature neurons via the Wnt signaling pathway |
| PMC10152985__F15 | Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications |
| PMC10153444__F2 | Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders |
| PMC10153643__F2 | Thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans |
| PMC10158029__F12 | The regulator mechanism of S100A16 in Glioma |
| PMC10158519__F7 | Schematic diagram by GroA promotes of expressions of inflammatory mediator TNFA and COX-2 by activating NOD1/RIPK2-mediated JNK, ERK and p38 MAPK pathways in HNSCC progression and metastasis |
| PMC10159521__F9 | miR-613 suppresses renal cell carcinoma proliferation, invasion and migration by regulating the AXL/AKT pathway |
| PMC10173380__F7 | Schematic diagram illustrating the mechanisms through which VNN1 in PC cells induces Beta-cell dedifferentiation by inhibiting the AMPK/GAPDH/Sirt1/FoxO1 signaling pathway |
| PMC10177044__F2 | Ratio of p38 signaling to ERK determines whether cancer cells enter a dormant state or undergo proliferation |
| PMC10177097__F9 | Effects induced by Exe plus CBD in MCF-7aro cells |
| PMC10177107__F1 | Different signaling pathways and epigenetic mechanisms that have been deregulated during TNBC progression and growth, contributing to stemness |
| PMC10177184__F6 | Evolutionary chart of human molecular pathway Akt |
| PMC10177184__F7 | Evolutionary chart of human molecular pathway of EGFR signaling (A), Notch (B), and Hedgehog (C) pathways |
| PMC10177184__F9 | Evolutionary chart of human molecular pathway of WNT signaling |
| PMC10177463__F3 | BRAF V600-Mutated Metastatic Melanoma and Targeted Therapy Resistance: An Update of the Current Knowledge |
| PMC10177541__F9 | Effects and mechanisms of SQSTM1/p62 on migration and invasion of HCC |
| PMC10178209__F4 | Biosynthetic pathway to produce patchoulol and Alpha- and Beta-santalol in S |
| PMC10178416__F2 | Schematic drawing presenting signaling pathways affected by ferulic acid |
| PMC10178434__F2 | D+ synthesis pathways |
| PMC10178469__F2 | Downstream signaling pathway of TLRs |
| PMC10178682__F1 | Simplified picture of cancer metabolism |
| PMC10178712__F5 | RNA-sequencing analysis revealed the role of trimethylamine-N-oxide (TMAO)-mediated signaling in vascular dementia |
| PMC10178966__F3 | Potential biotargets associated with the CI−AKI |
| PMC10179184__F2 | Mechanism of CYLD function in oxidative stress-induced DNA damage |
| PMC10179295__F2 | Paxillin participates in Wnt, integrin-FAK, and TGFB signaling pathways |
| PMC10179295__F3 | Paxillin participates in MAPK and PI3K/AKT signaling pathways |
| PMC10179314__F1 | PI3K/AKT/mTOR Dysregulation and Reprogramming Metabolic Pathways in Renal Cancer: Crosstalk with the VHL/HIF Axis |
| PMC10179536__F9 | Proposed diagram for the therapeutic effect of PRP improved bladder overactivity induced by OHD in rat model |
| PMC10179549__F10 | HMGB2 in the development of the diseases |
| PMC10179672__F4 | Ligands, receptors, and transcriptional regulators of Hedgehog signaling pathway |
| PMC10179672__F5 | Key components involved in the regulation of activation/inactivation of the canonical or Wnt/Beta-catenin pathway |
| PMC10179893__F5 | PS inhibits macrophage M2 polarization via IL-4/STAT6 signaling pathway, and in turn suppresses TAM-induced tumor progression |
| PMC10180405__F3 | BMP-2 and Wnt/Beta-catenin signaling pathways participate in the pharmacological activity of naringin in mediating osteogenic differentiation |
| PMC10180667__F4 | “Components-targets-pathways” network |
| PMC10180667__F5 | Effect of FS on toll-like receiver signaling pathway |
| PMC10181252__F1 | Wnt/Beta-catenin signaling pathway in tumor progression |
| PMC10181252__F2 | Various flavonoids on the Wnt/Beta-catenin pathway |
| PMC10181312__F2 | Circadian clock system involved in regulating photoperiodic flowering in Arabidopsis, soybean, and rice |
| PMC10187169__F2 | Pathways included in the model |
| PMC10189743__F5 | Involvement of ITGA and ITGB receptors in ‘focal adhesion’ and ‘ECM receptor interaction’ from the Kyoto Encyclopaedia of Genes and Genomes pathway database |
| PMC10189745__F1 | IL-36 signaling pathway |
| PMC101920__F1 | Late steps of AdoCbl biosynthesis in S |
| PMC10193374__F1 | In wound healing, CTHRC1 can recruit additional M2 macrophages to the wound site to promote skin repair and activate the TGFB and Notch pathways |
| PMC10193376__F4 | Protein network encoded by jointly regulated genes |
| PMC10197881__F9 | Proposed mechanisms |
| PMC10198048__F7 | Working model of how Cas regulates osteoclastogenesis |
| PMC10198710__F2 | m6A methylases that participate in cancer glycolytic metabolic pathways |
| PMC10198710__F3 | m6A methylases that participate in ferroptosis |
| PMC10203752__F3 | Mechanisms of proanthocyanidins in treatment of HSP |
| PMC10215085__F9 | Hypothetical molecular mechanism model was developed for the influence of starch on the growth and proliferation of B |
| PMC10215119__F1 | Mechanisms involved in the regulation of macrophage polarization by exosomal ncRNA in AS |
| PMC10215262__F1 | Canonical Wnt pathway |
| PMC10215262__F2 | Studies related to the role of the Wnt/Beta-catenin signaling pathway in Acute Myeloid Leukemia |
| PMC10215516__F2 | PI3K/AKT/mTOR signaling pathway activation in HPV-positive HNCs |
| PMC10215584__F5 | PPI network analysis according to STRING database and KEGG pathway enriched in DEPs in the groups of (A) MRC vs |
| PMC10215600__F1 | Nrf2 and SIRT1 signaling pathways regulation by antioxidants |
| PMC10215719__F7 | Proposed mechanisms of the effect of Ptn overexpression (A) and the pharmacological inhibition of RPTPB/ζ with MY10 (B) on some of the principal signaling pathways implicated in ethanol and/or LPS acute response in adolescent mice |
| PMC10215824__F3 | Obesity-altered adiponiche and tumour development: some novel proposed mechanisms in mature adipocytes and precursor cells |
| PMC10215861__F3 | Roles of RONSs during skeletal muscle pathologies |
| PMC10216079__F3 | Main signaling pathway in rheumatoid arthritis |
| PMC10216084__F8 | TRPV4 and TRPM8 signalling pathways relevant to the present study |
| PMC10216109__F2 | Melatonin antioxidant properties and tryptophan metabolic pathway |
| PMC10216286__F1 | The TRAIL apoptosis pathway |
| PMC10216286__F2 | TRAIL resistance |
| PMC10216337__F2 | Schematic representing the suspected roles of and molecular pathways involving MeCP2 in colorectal-cancer progression |
| PMC10216337__F3 | Schematic representing the suggested roles of and molecular pathways involving MeCP2 in pancreatic cancer |
| PMC10216337__F6 | Schematic representing the suspected roles of and molecular pathways involving MeCP2 in prostate-cancer progression |
| PMC10216404__F2 | Effects of RSV on activation of SIRT1 signalling pathway |
| PMC10216404__F4 | Effects of RSV on the regulation of microRNAs and BMP2 signalling in protecting bone |
| PMC10216440__F2 | CGRP cellular pathway |
| PMC10216514__F5 | Ferroptosis signaling pathway |
| PMC10216531__F1 | The fundamental parts of TLR4 signaling |
| PMC10216619__F2 | Adiponectin paradox and its related pathways during COVID-19 infection |
| PMC10216619__F4 | Possible neurological and mental COVID-19 outcomes related to the angiotensin-converting enzyme 2/Mas/brain-derived neurotrophic factor (ACE2\Mas\BDNF) signaling pathway occupation by SARS-CoV-2 |
| PMC10216727__F2 | Role and function of FOXM1 in pulmonary fibrosis |
| PMC10216727__F3 | Proposed mechanism of vagus-mediated liver regeneration |
| PMC10216727__F6 | EGFR/mTOR signaling pathways that regulate FOXM1 are involved in Beta-cell proliferation |
| PMC10216802__F2 | LPS (TLR4)-mediated inflammation and its interplay with RhoA activation and the downstream ROCK signaling pathways |
| PMC10217168__F14 | Graphical summary of the protective effect of Lactiplantibacillus plantarum Lac16 against enterohemorrhagic E |
| PMC10217556__F1 | Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain |
| PMC10217562__F5 | KEGG diagram of plant hormone signal transduction pathway under salt stress |
| PMC10217757__F1 | Specific Features of Focal Cortical Dysplasia in Tuberous Sclerosis Complex |
| PMC10217969__F5 | Transcriptome and Metabolome Reveal Distinct Sugar Accumulation Pattern between PCNA and PCA Mature Persimmon Fruit |
| PMC10218028__F2 | SNPs affecting NET formation |
| PMC10218067__F7 | Rhein Induces Oral Cancer Cell Apoptosis and ROS via Suppresse AKT/mTOR Signaling Pathway In Vitro and In Vivo |
| PMC10218387__F3 | Major pathways of carbon and energy metabolism in M382 |
| PMC10218397__F9 | TASE and thymol supplementation in neuronal differentiation and outgrowth effect |
| PMC10218668__F1 | Therapeutic peptides for lung diseases |
| PMC102186__F9 | Ras-mediated signaling pathways |
| PMC10218870__F1 | Schematic diagram showing the main molecular targets of luteolin during the initial steps of the metastatic cascade |
| PMC10221447__F3 | Natural Products Targeting PI3K/AKT in Myocardial Ischemic Reperfusion Injury: A Scoping Review |
| PMC102215__F1 | Pathways to Lignin Monomers.The "metabolic grid" shown in this scheme incorporates the results of recent studies suggesting previously unexpected substrate specificities for F5H and COMT (; ; ) |
| PMC10221877__F8 | Response of DA metabolic pathway to Cd stress in duckweed |
| PMC10222038__F1 | Vitamin D metabolic pathway |
| PMC10222048__F3 | KEGG pathway analysis of glycolysis and gluconeogenesis |
| PMC10222229__F2 | Roles of protein phosphatases in liver regeneration |
| PMC10222578__F5 | Networks of interactions between the genes affected by the production of sfRNA in ZIKV infection of human brain organoids |
| PMC10222578__F6 | Interconnection between sfRNA-affected biological processes in ZIKV-infected human brain organoids |
| PMC10223558__F5 | Networking among differentially expressed genes (DEGs) and pathways identified via GSEA |
| PMC10223558__F6 | Identification of key hub genes |
| PMC10223558__F8 | Expression analysis of genes involved in PI3-AKT-mTOR pathway post MMTV expression |
| PMC10223772__F5 | Proteins related to resistance in HIGS lines infected with A. flavus |
| PMC10224166__F3 | Anti-inflammatory effect and mechanism of atractylenolide I and III |
| PMC10224166__F4 | Anti-cancer effects and mechanism of atractylenolide I, II, and III |
| PMC10224264__F3 | Hypothesized mechanism of coronavirus-induced neuronal damage via oxidative stress and mitochondria dysfunction |
| PMC10224264__F5 | Anti-apoptotic and anti-inflammatory effects of Ginkgo biloba extract (EGb) and its constituents |
| PMC10229232__F1 | Krüppel-homologue 1 regulates the development of Tuta absoluta and its cascade regulation pattern in the juvenile hormone signalling pathway |
| PMC10232107__F2 | Compound-gene targets-signaling pathway network of the eight phytochemicals related to neuroinflammation |
| PMC10236263__F6 | Models of the positive regulatory feedback loop of p65/miR-27a-3p/TAB3/NFKB axis |
| PMC10237023__F2 | Intratumour microbiome of pancreatic cancer |
| PMC10237620__F1 | MTOR signaling pathway in cardiac aging |
| PMC10239166__F1 | Transcriptional regulation on effector T cells in the pathogenesis of psoriasis |
| PMC10239240__F5 | Mettl3 Mediated m6A Methylation Involved in Epithelial-Mesenchymal Transition by Targeting SOCS3/STAT3/SNAI1 in Cigarette Smoking-Induced COPD |
| PMC10239259__F2 | Association Between Sarcopenia and Diabetes: From Pathophysiology Mechanism to Therapeutic Strategy |
| PMC10239456__F3 | Interaction graph and dynamic behavior of the PanNETs Boolean model |
| PMC10239497__F10 | Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6 |
| PMC10239510__F7 | Paradigm summarizing the thermogenic and anti-inflammatory properties of YJT via the gut microbiota and related multiple signaling pathways |
| PMC10239578__F4 | Differential molecular pathway expression according to chemotherapeutic response in ovarian clear cell carcinoma |
| PMC10239798__F7 | Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A |
| PMC10239817__F1 | Peptides in reversing chemoresistance of breast cancer: current facts and future prospects |
| PMC10239924__F1 | Raptor in lymphocytes differentiation and function |
| PMC10241773__F2 | Epigenetic regulation and therapeutic targets in the tumor microenvironment |
| PMC10242022__F1 | Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis |
| PMC10242070__F5 | Transcriptomic signatures reveal a shift towards an anti-inflammatory gene expression profile but also the induction of type I and type II interferon signaling networks through aryl hydrocarbon receptor activation in murine macrophages |
| PMC10242111__F4 | Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations |
| PMC10242157__F7 | Versatile role of Serpina3c in physiological and pathological processes: a review of recent studies |
| PMC10242177__F1 | Myostatin: a potential therapeutic target for metabolic syndrome |
| PMC10242330__F2 | Autophagy: A challengeable paradox in cancer treatment |
| PMC10242642__F1 | SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia |
| PMC10242764__F5 | Construction of drug-compound-target-pathway network |
| PMC10242764__F7 | Molecular Mechanisms of Notopterygii rhizoma Et Radix for Treating Arrhythmia Based on Network Pharmacology |
| PMC10242860__F4 | Ferritin in cancer therapy: A pleiotropic tumoraffin nanocage‐based transport |
| PMC10242999__F2 | Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer |
| PMC10242999__F3 | Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer |
| PMC10243030__F7 | NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway |
| PMC10243112__F7 | Machine Learning Reveals Lipidome Remodeling Dynamics in a Mouse Model of Ovarian Cancer |
| PMC10243463__F1 | BMP4 signaling in trophoblast emergence from pluripotency |
| PMC10243706__F1 | Necrotizing enterocolitis in premature infants—A defect in the brakes? Evidence from clinical and animal studies |
| PMC10243716__F2 | Ferroptosis as a vulnerability in cancer |
| PMC10243851__F1 | Clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis |
| PMC10244093__F9 | Linc00662 m6A promotes the progression and metastasis of pancreatic cancer by activating focal adhesion through the GTF2B-ITGA1-FAK pathway |
| PMC10244098__F2 | N7-methylguanosine modification: from regulatory roles to therapeutic implications in cancer |
| PMC10244118__F8 | Ly6D facilitates chemoresistance in laryngeal squamous cell carcinoma through miR-509/Beta-catenin signaling pathway |
| PMC10244546__F1 | Potential of epigallocatechin gallate in the chemoprevention and therapy of hepatocellular carcinoma |
| PMC10244677__F1 | Integrated high-throughput analysis identifies super enhancers in metastatic castration-resistant prostate cancer |
| PMC10244678__F9 | Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway |
| PMC10244910__F10 | Neferine attenuates development of testosterone-induced benign prostatic hyperplasia in mice by regulating androgen and TGFB/Smad signaling pathways |
| PMC10245950__F10 | TCA cycle is affected by oxaliplatin |
| PMC10245950__F12 | Glycolysis in cardiomyocytes is upregulated in the oxaliplatin treated mice |
| PMC10245950__F13 | Effect of oxaliplatin on NAD+ and NADP+ synthesis and salvage pathways |
| PMC10245950__F9 | ß-oxidation pathway for fatty acids is strongly downregulated by oxaliplatin |
| PMC10251820__F1 | Modern Management and Diagnostics in HER2+ Breast Cancer with CNS Metastasis |
| PMC10252036__F2 | Various mechanisms that have been reported to regulate epithelial–mesenchymal transition (EMT) in SACC patients |
| PMC10252624__F1 | Mechanisms of VEGF (receptor) inhibitors-induced cardiovascular complications |
| PMC10252624__F2 | Primary mechanisms of ICIs-associated cardiotoxicity |
| PMC10252649__F1 | mTOR Signaling Pathway in Bone Diseases Associated with Hyperglycemia |
| PMC10253150__F6 | Wnt signaling pathway, including the canonical pathway, the pathway associated with cell polarity determination (Wnt/PCP), and an increase in intracellular Ca2+ (Wnt/Ca2+), whose genes were significantly regulated in the ZG zone |
| PMC10253150__F7 | Biogenic amine synthesis signaling pathway, whose genes were characterized by expression significantly regulated in the adrenal medulla |
| PMC10253263__F6 | Signaling pathway of PNPLA3-I148M-induced activation of LX-2 cells |
| PMC10253306__F2 | Interactions found in polyQ-containing ID hub proteins located in both cytoplasm and nucleus using protein interaction annotation of HPRD |
| PMC10253306__F3 | Splicing Modulators Are Involved in Human Polyglutamine Diversification via Protein Complexes Shuttling between Nucleus and Cytoplasm |
| PMC10253382__F3 | Anti-inflammatory pathways induced by baicalin |
| PMC10253447__F1 | Notch signaling pathway inhibition leads to intestinal differentiation |
| PMC10253447__F2 | Hedgehog signaling pathway in the development of intestinal metaplasia in the distal esophagus |
| PMC10253478__F1 | Action of probiotics |
| PMC10253673__F1 | Potential mechanisms by which alcohol modulates Alzheimer’s disease (AD) pathology |
| PMC10254162__F11 | FAK/Src signaling pathway |
| PMC10254355__F4 | CIN and MSI signaling pathways in colorectal epithelial cancer: A modified cartoon from KEGG depicts known activated pathways in colorectal epithelial cells |
| PMC10255413__F2 | Biosynthetic pathway of chlorophyll |
| PMC10255416__F7 | Supplementation affects metabolic reprogramming of cumulus cells in aging ovarian patients |
| PMC10255599__F2 | Vitamin D and resveratrol immune response against SARS-CoV-2 infection |
| PMC10255599__F3 | Anti-oxidant and anti-thrombotic activity of Vitamin D and Resveratrol in COVID-19 |
| PMC10258460__F1 | Novel Metabolic Detour for Pancreatic Cancer Survival |
| PMC10260623__F1 | Schematic of the clock pathway |
| PMC10266770__F1 | STAT2 deficiency and other inborn and acquired defects of type I IFN signaling result in susceptibility to viral infections |
| PMC10266771__F1 | Proposed mechanism for the regulation of NRAS mutation-driven hematopoietic malignancies involves the CBL/JAK2/RAB27B signaling axis |
| PMC10272955__F8 | Graphical summary of the signaling pathway that mediates fenofibrate (FF)-induced cytoprotection against cisplatin toxicity |
| PMC10273736__F2 | Review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies |
| PMC10273736__F3 | Review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies |
| PMC10273736__F5 | Review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies |
| PMC10275075__F5 | Population response of intestinal microbiota to acute Vibrio alginolyticus infection in half-smooth tongue sole (Cynoglossus semilaevis) |
| PMC10276824__GA | FOXO1 regulates Th17 cell-mediated hepatocellular carcinoma recurrence after hepatic ischemia-reperfusion injury |
| PMC10278599__F2 | CAR T cell cytolytic mechanisms and paracrine effects |
| PMC10280140__F11 | TGF‐B‐induced PI3K/AKT/mTOR pathway |
| PMC10281733__F10 | LPS-antagonist potential of Q3G on pulmonary injury |
| PMC10286592__F1 | How TBI altered calcium dependent PLC pathways, oxygen species scavenging system and p53 signalling |
| PMC10286592__F3 | Alteration of mTOR signalling pathway post TBI |
| PMC10286596__F1 | Mitochondrial biogenesis in neurons |
| PMC10286596__F2 | Resveratrol-modulated mitochondrial biogenesis in neurodegenerative diseases |
| PMC10288531__F2A | Differential Pathway Expression of Cardiac Muscle Contraction Pathway |
| PMC10288531__F3A | Differential Pathway Expression of Antigen Processing and Presentation |
| PMC10295080__F1 | Nrf2 signalling pathway |
| PMC10295928__F5 | MiRNA-assisted targeted therapy |
| PMC10295928__F6 | MiRNA-assisted immunotherapy |
| PMC10296091__F1 | A2AR effects in microglia, astrocytes, and synapses under physiological conditions |
| PMC10296498__F1 | IL-33/ST2 signaling pathway activation |
| PMC10296674__F3 | Canonical pathways derived using the IPA tool |
| PMC10296705__F2 | Biosynthesis pathways of isoprenoids and the biosensors that are responsive to isoprenoids and their precursors |
| PMC10296711__F10 | Molecular Basis and Clinical Consequences of Chronic Inflammation in Prostatic Diseases: Prostatitis, Benign Prostatic Hyperplasia, and Prostate Cancer |
| PMC10296711__F12 | Schematic illustration of the IL1-R/TLR/NFKB pathway with emphasis on activation of different NFKB subunits via the IRAK1/TRAF6-mediated pathway |
| PMC10296711__F5 | Schematic illustration of the activation process of TLR receptors and their downstream signaling molecules upon activation forming the TLR-MYD88-IRAK1/4-TRAF6-NFKB/IRF or TLR3/TLR4-TRIF-IRF/NFKB signaling pathways |
| PMC10296711__F8 | Schematic illustration of the TLR/IL1/IRAK/NFKB inflammatory signaling pathway axis |
| PMC10296830__F1 | The Hippo pathway and YAP/TAZ mechanosignaling |
| PMC10297006__F2 | Ezrin controls several major cellular functions through the regulation of downstream signaling transduction pathways |
| PMC10297110__F5 | The effects of inhibiting TGFB signaling pathways on hCECs in vitro |
| PMC10297136__F3 | Signal pathways associated with lung adenocarcinoma |
| PMC10297136__F5 | Glioblastoma multiforme (GBM)-related signal pathways |
| PMC10297376__F2 | PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds |
| PMC10297881__F12 | Apoptosis and p53 signaling pathway in the control compared to adipocytes, chondrocytes, neural-like cells and osteoblasts |
| PMC10297881__F13 | Apoptosis and p53 signaling pathway in all analyzed groups |
| PMC10298151__F7 | Diagram showing the mechanisms involved in D2R Beta-arrestin-dependent pathway-mediated ERK activation |
| PMC10298332__F4 | The TNF signalling pathway by M-glucans |
| PMC10298332__F5 | The C-type lectin pathway by M-glucans |
| PMC10298332__F6 | The IL-17 signalling pathway by M-glucans |
| PMC10298365__F5 | Neonatal Meningitis-Causing Escherichia coli Induces Microglia Activation which Acts as a Double-Edged Sword in Bacterial Meningitis |
| PMC10298409__F11 | Integrated Transcriptomics and Metabolomics Analysis of the Fructan Metabolism Response to Low-Temperature Stress in Garlic |
| PMC10298860__F11 | Albino phenotype of ‘HJY’ might be modulated by a plastid retrograde signaling pathway |
| PMC10299014__F1 | IL-17RA/RC signalling pathways (Figure adapted from Monin and Gaffen , and from Chung ) |
| PMC10299070__F3 | Core pathways involved in development of Peyronie’s disease and their interrelationships |
| PMC10299133__F1 | HGF/MET signaling pathway and most frequent alterations in NSCLC |
| PMC10299161__F4 | Oxidative stress promotes the activation of programmed cell death initiated by intrinsic apoptotic signaling in the mitochondria or extrinsic apoptotic signaling by death receptor pathways in CRC cells |
| PMC10299206__F2 | TGFB signaling pathway |
| PMC10299206__F3 | Relationship between genes related to TGFB signaling pathway and pathogenesis of oral cancers |
| PMC10299455__F2 | NOTCH signaling pathway, ligands, and inhibitors |
| PMC10299596__F1 | BCR signaling pathway and BTKis resistance in CLL |
| PMC10299676__F1 | Mechanisms for activation of the JAK-STAT signaling pathway |
| PMC10300409__GA1 | Oncolytic therapy with recombinant vaccinia viruses targeting the interleukin-15 pathway elicits a synergistic response |
| PMC10300974__F5 | Hypericum perforatum L. and the Underlying Molecular Mechanisms for Its Choleretic, Cholagogue, and Regenerative Properties † |
| PMC10300995__F2 | Altered amino acid metabolism and potential drugs in DLBCL |
| PMC10300995__F3 | Altered fatty acid metabolism and potential drugs in DLBCL |
| PMC10300995__F4 | Influence of altered tumor metabolism on immune cells |
| PMC10301029__F1 | Tyrosine kinase (EGF pathway) and Wnt/Beta-catenin pathways |
| PMC10301029__F2 | Overlap between the tyrosine kinase pathway, Wnt/Beta-catenin, and prostaglandin inflammation pathways |
| PMC10301029__F3 | EMT transition pathway |
| PMC10301361__F4 | Involvement of the cytoskeleton in the immune response to viral infections |
| PMC10302309__F2 | Resistance to EGFR-TKIs in Non-Small Cell Lung Cancer: From Molecular Mechanisms to Clinical Application of New Therapeutic Strategies |
| PMC10302777__F2 | Betaine as a Functional Ingredient: Metabolism, Health-Promoting Attributes, Food Sources, Applications and Analysis Methods |
| PMC10302997__F1 | Emerging role of autophagy in colorectal cancer: Progress and prospects for clinical intervention |
| PMC10304117__F1 | ASFV proteins modulating the cGAS/STING and NFKB signaling pathway (Created with BioRender |
| PMC10304248__F2 | Mycobacterium tuberculosis and apoptosis modulation |
| PMC10304248__F3 | Mycobacterium tuberculosis and the necrotic-like cell death modulation |
| PMC10304357__F1 | Targeting cGAS/STING signaling-mediated myeloid immune cell dysfunction in TIME |
| PMC10304636__F4 | Schematic diagram representing cardioprotective molecular mechanisms of GLP-1 analogs in cardiomyocytes |
| PMC10304648__F1 | Detection of influenza A virus infection by pattern recognition receptors (PRRs) and NLRP3 inflammasome |
| PMC10304713__F2 | SARS-CoV-2 employs different mechanisms to activate the host’s innate immune system |
| PMC10305000__F6 | Reconstructed fatty acid synthesis pathway of ST7-B |
| PMC10305525__F2 | Three major H2S synthesis pathways are of enzymatic, non-enzymatic, and gut microbial origin |
| PMC10305623__F1 | 11-oxygenated androgens in prostate cancer |
| PMC10307880__F2 | Viral-mimicry response induced by DNMTis |
| PMC10308077__F2 | Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective |
| PMC10308129__F2 | Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes |
| PMC10308129__F4 | Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes |
| PMC10308129__F7 | Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes |
| PMC10308132__F1 | Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies |
| PMC10308135__F4 | Mechanistic insight into lysyl oxidase in vascular remodeling and angiogenesis |
| PMC10308199__F3 | Cysteine dioxygenase type 1 (CDO1): Its functional role in physiological and pathophysiological processes |
| PMC10308384__F5 | Therapeutic strategies to recover ependymal barrier after inflammatory damage: relevance for recovering neurogenesis during development |
| PMC10308384__F9 | Therapeutic strategies to recover ependymal barrier after inflammatory damage: relevance for recovering neurogenesis during development |
| PMC10308444__F5 | Integrated transcriptome and microRNA sequencing analyses reveal gene responses in poplar leaves infected by the novel pathogen bean common mosaic virus (BCMV) |
| PMC10308667__F1 | Comprehensive insight into the correlation between ncRNAs and the Wnt/Beta-catenin signalling pathway in gastric cancer pathogenesis |
| PMC10308667__F2 | Comprehensive insight into the correlation between ncRNAs and the Wnt/Beta-catenin signalling pathway in gastric cancer pathogenesis |
| PMC10308667__F3 | Comprehensive insight into the correlation between ncRNAs and the Wnt/Beta-catenin signalling pathway in gastric cancer pathogenesis |
| PMC10308769__F1 | First reported double drug–drug interaction in a cancer renal patient under everolimus treatment: therapeutic drug monitoring and review of literature |
| PMC10309183__F4 | Ether lipids and a peroxisomal riddle in sperm |
| PMC10309513__F2 | Triggering receptor expressed on myeloid cells 2–apolipoprotein E signaling pathway in diseases |
| PMC10309559__F2 | IFNB expression: focusing on the role of its promoter and transcription regulators |
| PMC10310354__F2 | Function of Akkermansia muciniphila in type 2 diabetes and related diseases |
| PMC10310766__F2 | Canonical pathway of p53 that regulates ferroptosis |
| PMC10310766__F3 | Noncanonical pathway of p53 that regulates ferroptosis |
| PMC10310781__F1 | Amyloid Beta-based therapy for Alzheimer’s disease: challenges, successes and future |
| PMC10310980__F1 | Circadian clocks in cancer: Mechanisms and clinical implications |
| PMC10310985__F4 | DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer |
| PMC10310986__F5 | Histone post-translational modification and the DNA damage response |
| PMC10311025__F8 | Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response |
| PMC10311035__F1 | Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders |
| PMC10311035__F2 | Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders |
| PMC10311035__F3 | Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders |
| PMC10311107__F7 | Metabolic and transcriptomic analyses elucidate a novel insight into the network for biosynthesis of carbohydrate and secondary metabolites in the stems of a medicinal orchid Dendrobium nobile |
| PMC10311114__F2 | Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges |
| PMC10311176__F3 | Transcriptome analysis of CD4+ T cells from HIV-infected individuals receiving ART with LLV revealed novel transcription factors regulating HIV-1 promoter activity |
| PMC10311182__F1 | Key piece of the airway remodeling puzzle revealed—LIGHT signaling in the lung |
| PMC10311254__F1 | Unlocking the power of precision medicine for pediatric low-grade gliomas: molecular characterization for targeted therapies with enhanced safety and efficacy |
| PMC10311505__F3 | YAP at the progression of inflammation |
| PMC10311566__F1 | Recent progress of peptide regulators for the Wnt/Beta-catenin signaling pathway |
| PMC10311568__F2 | Research progress of sophoridine’s pharmacological activities and its molecular mechanism: an updated review |
| PMC10311615__F11 | 18Beta-glycyrrhetinic acid inhibits proliferation of gastric cancer cells through regulating the miR-345-5p/TGM2 signaling pathway |
| PMC10311769__F2 | Revealing of a novel double bond reductase related to perilla ketone biosynthesis in Perilla frutescens |
| PMC10311893__F5 | MRI-based breast cancer radiogenomics using RNA profiling: association with subtypes in a single-center prospective study |
| PMC10312032__F2 | Research progress on the kynurenine pathway in the prevention and treatment of Parkinson’s disease |
| PMC10312162__F4 | Changes in the metabolic pathways of young and old leaves in the two soybean ecotypes |
| PMC10312928__F5 | Protein-protein interaction network and functional enrichment analysis of proteins with acetylation, carbamylation and phosphorylation sites regulated by bacterial lipopolysaccharide |
| PMC10312929__F8 | Wnt signaling pathway |
| PMC10312956__F3 | Networks of the rare-variant genes associated with suicidal behaviors in AI |
| PMC10313199__F3 | Advances in epigenetic modifications of autophagic process in pulmonary hypertension |
| PMC10313304__F9 | Exploring the active ingredients and mechanism of Shenzhi Tongxin capsule against microvascular angina based on network pharmacology and molecular docking |
| PMC10313365__F8 | Roadmap of molecular changes and cellular phenotypes when cells lose MLL3/4-COMPASS |
| PMC10313451__F6 | Imipramine mechanism of action in breast cancers |
| PMC10316197__F2 | Inflammation on NAFLD progression |
| PMC10316197__F3 | Apoptosis in NAFLD patient |
| PMC10318600__F1 | Signaling pathway of ferroptosis |
| PMC10334824__F5 | Prospective application of lncRNAs in the treatment of diabetic wounds |
| PMC10336275__F3 | CREB-induced immune response |
| PMC10340243__F5 | The main metabolic pathways of unsaturated fatty acids |
| PMC10340761__F4 | Gene interaction pathways and their regulation in cancer |
| PMC10340792__F2 | Targeting transcription factor YY1 for antitumor therapy |
| PMC10341168__F9 | Ginsenoside Rh4 Improves Hepatic Lipid Metabolism and Inflammation in a Model of NAFLD by Targeting the Gut Liver Axis and Modulating the FXR Signaling Pathway |
| PMC10341274__F2 | Contrasting roles of AGRP and POMC neurons in glucose and lipid homeostasis |
| PMC10341343__F2 | Glucose metabolism in cancer cells |
| PMC10341567__F1 | Main pathways involved in cholesterol transport involved in Alzheimer’s Disease |
| PMC10341567__F3 | Major pathways and interactions regulated by GSK3B: (A) Wnt/B-catenin pathway and (B)PI3K/Akt/mTor pathway |
| PMC10341567__F4 | Major pathways and interactions regulated by BACE1: (A) Notch signaling pathway, (B) Amyloidogenic pathway, and (C) NFKB pathway |
| PMC10341567__F5 | Major signaling pathways that regulate SREBP2 activation during cholesterol synthesis: (A) P53 pathway, and (B) Akt pathway |
| PMC10341567__F6 | Major pathways in which ABCA1 plays an important role for cholesterol transport in brains: (A) Reverse cholesterol transport pathway, (B) LXR/RXR pathway, and (C) SREBP2 pathway |
| PMC10341567__F7 | TREM2/DAP12 pathway |
| PMC10341681__F2 | Signaling pathways and targets of AB metabolism regulation by saponins |
| PMC10341681__F3 | Signaling pathways and targets of saponin-regulated tau protein phosphorylation |
| PMC10341681__F4 | Signaling pathways and targets of saponins against neuroinflammation in AD |
| PMC10341681__F5 | Signaling pathways and targets of saponins against oxidative stress in AD |
| PMC10341681__F6 | Signaling pathways and targets of saponins against apoptosis in AD |
| PMC10341762__F1 | One-carbon metabolism |
| PMC10341911__F3 | Syntenic analysis of genes in the Moso bamboo and rice cytokinin pathway families |
| PMC10341927__F10 | Identification of Moesin (MSN) as a Potential Therapeutic Target for Colorectal Cancer via the Beta-Catenin-RUNX2 Axis |
| PMC10341937__F2 | Canonical Wnt signal transduction pathway |
| PMC10341943__F3 | Role of the Notch pathway in cell-fate decisions in the somite |
| PMC10341994__F8 | Mechanism of AM polarization toward M1 phenotype and early apoptosis induced by rLLB exposure |
| PMC10342783__F9 | Phenylalanine metabolism (a) and neuroactive ligand-receptor interaction (b) KEGG pathway |
| PMC10342868__F8 | Regulatory mechanism of lncRNA 220 |
| PMC10343257__F10 | Therapeutic Effects and Molecular Mechanism of Chlorogenic Acid on Polycystic Ovarian Syndrome: Role of HIF-1alpha |
| PMC10343400__F6 | Glycosides and UC-related receptors AND transcriptional regulation |
| PMC10343815__F5 | Differentially expressed genes in the cAMP metabolic pathway suggested that upregulated genes were dominant in this pathway |
| PMC10343931__F4 | Possible mechanisms by which exercise upregulates NAD+ to improve mitochondrial autophagy |
| PMC10344634__F10 | Graphical abstract |
| PMC10346248__F11 | Schematic models of the NRF2 signaling pathway and its regulatory mechanisms in human skeletal muscle |
| PMC10346484__F2 | Key metabolic pathways for the biosynthesis of NEAAs, the enzymes in each pathway, and the main functions of each AA [54,173] |
| PMC10346897__F4 | Mechanism by which PUFAs suppress cholesterol synthesis via inhibition of the signaling pathway of sterol regulatory element-binding protein-1 (SREBP-1) [74] |
| PMC10348770__F1 | Treg-mediated immunosuppression and resolution of lung inflammation |
| PMC10353343__F4 | Gene expression changes for genes in the Toll-like receptor 4 (TLR4) Signaling Pathway |
| PMC10357943__F3 | Shining a light on the dark proteome: Non‐canonical open reading frames and their encoded miniproteins as a new frontier in cancer biology |
| PMC10367548__F8 | The mechanism by purinergic receptor P2Y12 drives ConA-mediated autoimmune hepatitis through hexokinase 2-dependent glycolysis pathway |
| PMC10367551__F8 | Mechanism by which miR-552-3p alleviates liver fibrosis and inflammation |
| PMC10367567__F1 | CXCL12-CXCR4/CXCR7 signaling pathway |
| PMC10369979__F1 | An oligonucleotide-based cGAS agonist for cancer immunotherapy |
| PMC10372241__F1 | New insights into regulatory cell death and acute pancreatitis |
| PMC10372325__F6 | Transcriptomic and physiological analyses reveal temporal changes contributing to the delayed healing response to arterial injury in diabetic rats |
| PMC10372646__F1 | Pomegranate-specific natural compounds as onco-preventive and onco-therapeutic compounds: Comparison with conventional drugs acting on the same molecular mechanisms |
| PMC10373067__F2 | Bispecific antibody targeting TGFB and PD-L1 for synergistic cancer immunotherapy |
| PMC10373097__S1 | Rationally designed cancer vaccine based on NIR-II fluorescence image-guided light-triggered remote control of antigen cross-presentation and autophagy |
| PMC10373120__F5 | Regulatory pathway involving lncRNA H19, miR-124-3p and ITGB3 in modulating ectopic endometrial cell proliferation and invasion in endometriosis |
| PMC10373173__F2 | Matrix metalloproteinases in rheumatoid arthritis and osteoarthritis: a state of the art review |
| PMC10373932__F5 | Insights into the physiological and genomic characterization of three bacterial isolates from a highly alkaline, terrestrial serpentinizing system |
| PMC10374032__F1 | Genome-scale metabolic modeling and in silico analysis of opportunistic skin pathogen Cutibacterium acnes |
| PMC10374212__F3 | NLRP3: a new therapeutic target in alcoholic liver disease |
| PMC10374481__F7 | HAMLET effect on cell death and mitochondrial respiration in colorectal cancer cell lines with KRAS/BRAF mutations |
| PMC10374575__F6 | GHS-R1a/D2R heterodimers activation in dopaminergic neurons |
| PMC10374588__F2 | Pathways controlling pyroptosis, apoptosis, ferroptosis, and cuproptosis |
| PMC10374588__F4 | Graphical depiction of the mechanism of classical pyroptosis pathway and non-classical pyroptosis pathway |
| PMC10374606__F8 | Prx II knock-down HaCaT cells are sensitive to H2O2 stimulation |
| PMC10374640__F5 | Pharmacological mechanism of Beta-elemene in the treatment of esophageal cancer revealed by network pharmacology and experimental verification |
| PMC10374743__F2 | Warburg effect: a score for many instruments in the concert of cancer and cancer niche cells |
| PMC10374777__F2 | Molecular mechanism of ferulic acid and its derivatives in tumor progression |
| PMC10375050__F2 | Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease |
| PMC10375050__F3 | Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease |
| PMC10375321__F1 | One-carbon metabolism comprising the transmethylation pathway, nucleotide synthesis pathway, transsulfuration pathway and remethylation pathway |
| PMC10375449__F8 | Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis |
| PMC10375641__F5 | Super-enhancers complexes zoom in transcription in cancer |
| PMC10375653__F2 | Involvement of the SIRT1-NLRP3 pathway in the inflammatory response |
| PMC10375783__F2 | Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy |
| PMC10375783__F3 | Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy |
| PMC10375937__F1 | Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway |
| PMC10375937__F13 | Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway |
| PMC10375937__F14 | Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway |
| PMC10376127__F1 | Coenzyme Q functions |
| PMC10376127__F2 | New Insights on the Uptake and Trafficking of Coenzyme Q |
| PMC10376142__F1 | Cancer Drug Delivery Systems Using Bacterial Toxin Translocation Mechanisms |
| PMC10376170__F2 | Targeting Triple-Negative Breast Cancer by the Phytopolyphenol Carnosol: ROS-Dependent Mechanisms |
| PMC10376197__F2 | TRP Channels in Tumoral Processes Mediated by Oxidative Stress and Inflammation |
| PMC10376197__F3 | TRP Channels in Tumoral Processes Mediated by Oxidative Stress and Inflammation |
| PMC10376197__F4 | TRP Channels in Tumoral Processes Mediated by Oxidative Stress and Inflammation |
| PMC10376369__F5 | Alzheimer’s Disease and Green Tea: Epigallocatechin-3-Gallate as a Modulator of Inflammation and Oxidative Stress |
| PMC10376369__F7 | Alzheimer’s Disease and Green Tea: Epigallocatechin-3-Gallate as a Modulator of Inflammation and Oxidative Stress |
| PMC10376516__F4 | Recent Advances in Nanomaterials-Based Targeted Drug Delivery for Preclinical Cancer Diagnosis and Therapeutics |
| PMC10376673__F1 | Breaking Bad: Inflammasome Activation by Respiratory Viruses |
| PMC10376827__F1 | Dissecting the Protective Effect of CD8+ T Cells in Response to SARS-CoV-2 mRNA Vaccination and the Potential Link with Lymph Node CD8+ T Cells |
| PMC10376943__F4 | FGF1 Protects MCF-7 Cells against Taltobulin through Both the MEKs/ERKs and PI3K/AKT Signaling Pathway |
| PMC10376991__F8 | An Autophagy-Associated MITF–GAS5–miR-23 Loop Attenuates Vascular Oxidative and Inflammatory Damage in Sepsis |
| PMC10377020__F1 | ER Stress, the Unfolded Protein Response and Osteoclastogenesis: A Review |
| PMC10377020__F2 | ER Stress, the Unfolded Protein Response and Osteoclastogenesis: A Review |
| PMC10377024__F2 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377024__F3 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377024__F4 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377024__F5 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377024__F6 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377024__F7 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377024__F8 | Landscape of Genetic Mutations in Appendiceal Cancers |
| PMC10377042__F2 | Potential Influence of Uremic Toxins on the Homeostasis of Bones and Muscles in Chronic Kidney Disease |
| PMC10377067__F7 | Metabolic Profiles Point Out Metabolic Pathways Pivotal in Two Glioblastoma (GBM) Cell Lines, U251 and U-87MG |
| PMC10377123__F3 | Pharmacological Potential of Betulin as a Multitarget Compound |
| PMC10377129__F9 | Active Estrogen–Succinate Metabolism Promotes Heme Accumulation and Increases the Proliferative and Invasive Potential of Endometrial Cancer Cells |
| PMC10377333__F1 | Indoleamine 2,3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy |
| PMC10377462__F10 | Molecular Basis of Transglutaminase-2 and Muscarinic Cholinergic Receptors in Experimental Myopia: A Target for Myopia Treatment |
| PMC10377491__F1 | Landscape of Small Leucine-Rich Proteoglycan Impact on Cancer Pathogenesis with a Focus on Biglycan and Lumican |
| PMC10377498__F5 | Mitophagy: A Bridge Linking HMGB1 and Parkinson’s Disease Using Adult Zebrafish as a Model Organism |
| PMC10377641__F3 | Leptin: A Heavyweight Player in Obesity-Related Cancers |
| PMC10377897__F3 | KV Channel-Interacting Proteins in the Neurological and Cardiovascular Systems: An Updated Review |
| PMC10377916__F2 | Revisiting Estrogen for the Treatment of Endocrine-Resistant Breast Cancer: Novel Therapeutic Approaches |
| PMC10377929__F7 | Escin Activates Canonical Wnt/Beta-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3B in Cultured Human Dermal Papilla Cells |
| PMC10378139__F2 | Ferroptosis in Cancer Progression |
| PMC10378150__F1 | STAT3 deficiency prevents GVHD in target organs while preserving GVL activity in lymphohematopoietic tissues |
| PMC10378342__F2 | Intravenous Immunoglobulin in Kawasaki Disease—Evolution and Pathogenic Mechanisms |
| PMC10378552__F2 | Exploring the Molecular Complexity of Medulloblastoma: Implications for Diagnosis and Treatment |
| PMC10378680__F5 | The Piezo1 Mechanosensitive Channel in Heart Failure |
| PMC10378789__F2 | Revisiting the Role of Autophagy in Cardiac Differentiation: A Comprehensive Review of Interplay with Other Signaling Pathways |
| PMC10379122__F1 | Unravelling the Role of P300 and TMPRSS2 in Prostate Cancer: A Literature Review |
| PMC10379125__F5 | Transcriptome-Wide Identification and Response Pattern Analysis of the Salix integra NAC Transcription Factor in Response to Pb Stress |
| PMC10379139__F2 | Genetic Risk Factors Related to Coronary Artery Disease and Role of Transforming Growth Factor Beta 1 Polymorphisms |
| PMC10379230__F5 | Isoflurane Anesthesia’s Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model |
| PMC10379333__F3 | Pulmonary Sarcoidosis: Experimental Models and Perspectives of Molecular Diagnostics Using Quantum Dots |
| PMC10379376__F2 | Pluripotency-Associated microRNAs in Early Vertebrate Embryos and Stem Cells |
| PMC10379376__F5 | Pluripotency-Associated microRNAs in Early Vertebrate Embryos and Stem Cells |
| PMC10379484__F2 | Endothelin-1 in Health and Disease |
| PMC10379601__F5 | Hypocholesterolemic Potential of the Edible Algae Fucus vesiculosus: Proteomic and Quantitative PCR Analysis |
| PMC10379778__F1 | ARHGAP1 in Rho GTPase Inactivation during Metastasizing of Breast Cancer Cell Line MCF-7 after Treatment with Doxorubicin |
| PMC10379778__F2 | ARHGAP1 in Rho GTPase Inactivation during Metastasizing of Breast Cancer Cell Line MCF-7 after Treatment with Doxorubicin |
| PMC10379831__F1 | Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis |
| PMC10380015__F2 | Challenges and Future Trends in Atopic Dermatitis |
| PMC10380015__F3 | Activation of the adaptive immune system via various receptors, different interleukins and its receptors, and the Janus kinases (JAK) STAT pathway |
| PMC10380201__F7 | Small-Extracellular-Vesicle-Derived miRNA Profile Identifies miR-483-3p and miR-326 as Regulators in the Pathogenesis of Antiphospholipid Syndrome (APS) |
| PMC10380285__F1 | Influence of Single Nucleotide Polymorphisms on Vitamin D Receptor Protein Levels and Function in Chronic Liver Disease |
| PMC10380296__F5 | Significantly DEGs identified by KEGG in protein digestion and absorption pathways (ko04974) |
| PMC10380296__F6 | Transcriptional Modulation Reveals Physiological Responses to Temperature Adaptation in Acrossocheilus fasciatus |
| PMC10380296__F7 | Transcriptional Modulation Reveals Physiological Responses to Temperature Adaptation in Acrossocheilus fasciatus |
| PMC10380440__F2 | Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis |
| PMC10380440__F3 | Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis |
| PMC10380468__F2 | Investigation of the Effects of Metallic Nanoparticles on Fertility Outcomes and Endocrine Modification of the Hypothalamic-Pituitary-Gonadal Axis |
| PMC10380517__F2 | CDK4/6 Inhibitor Resistance in Hormone Receptor-Positive Metastatic Breast Cancer: Translational Research, Clinical Trials, and Future Directions |
| PMC10380530__F1 | Comprehensive Review: Unveiling the Pro-Oncogenic Roles of IL-1ß and PD-1/PD-L1 in NSCLC Development and Targeting Their Pathways for Clinical Management |
| PMC10380532__F2 | mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy |
| PMC10380532__F3 | mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy |
| PMC10380571__F2 | Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies |
| PMC10380572__F2 | Fc Epsilon RI–Neuroimmune Interplay in Pruritus Triggered by Particulate Matter in Atopic Dermatitis Patients |
| PMC10380638__F5 | Schematic presentation of low-dose IR-induced immune effects in the spleen of mice, according to Cho et al |
| PMC10380640__F4 | Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology |
| PMC10380707__F2 | Inflammation, Dopaminergic Brain and Bilirubin |
| PMC10380727__F2 | Bioactive Compounds and Cardiac Fibrosis: Current Insight and Future Prospect |
| PMC10380735__F1 | Molecular Mechanisms of Neuroinflammation in Alzheimer’s Disease, the Consequence of Neural Cell Death |
| PMC10380759__F2 | Clinical Significance of CD73 in Cancer |
| PMC10380785__F3 | Lignin, the Lignification Process, and Advanced, Lignin-Based Materials |
| PMC10380881__F1 | Genetic Modulation of the Erythrocyte Phenotype Associated with Retinopathy of Prematurity—A Multicenter Portuguese Cohort Study |
| PMC10380887__F1 | MTOR Signaling: Emerging Role of Cyclic Nucleotide-Dependent Protein Kinases and Implications for Cardiometabolic Disease |
| PMC10380929__F3 | PINNet: a deep neural network with pathway prior knowledge for Alzheimer's disease |
| PMC10380946__F1 | Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer |
| PMC10380946__F2 | Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer |
| PMC10380946__F3 | Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer |
| PMC10380946__F4 | Illustrates the apoptosis mechanisms triggered by DHA |
| PMC10380946__F5 | Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer |
| PMC10380946__F6 | Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer |
| PMC10380946__F7 | ARA on apoptotic death pathways |
| PMC10381003__F2 | The TLR signalling pathways with highlighted gene polymorphisms involved in OA susceptibility |
| PMC10381408__F3 | Compound K Production: Achievements and Perspectives |
| PMC10381408__F4 | Compound K Production: Achievements and Perspectives |
| PMC10382028__F1 | Plant-derived extracts and metabolic modulation in leukemia: a promising approach to overcome treatment resistance |
| PMC10382180__F3 | Immunity by tryptophan microbial metabolites |
| PMC10382489__F3 | PTMs involve some mechanisms in CVDs |
| PMC10382538__F7 | Schematic model of the anti-inflammatory effects of IL4I1 on LPS induced-ALI |
| PMC10382901__F5 | Genetic alterations in MED12 promote castration-resistant prostate cancer through modulation of GLI3 signaling |
| PMC10382948__F1 | Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology |
| PMC10383069__F2 | Understanding the Roles of Very-Long-Chain Polyunsaturated Fatty Acids (VLC-PUFAs) in Eye Health |
| PMC10383192__F1 | Peptide Vaccine Design Targeting KIT Mutations in Acute Myeloid Leukemia |
| PMC10383295__F2 | High levels of ROS promote cancer cell growth, proliferation, invasion, and metastasis |
| PMC10383295__F3 | Cancer Metabolism: The Role of ROS in DNA Damage and Induction of Apoptosis in Cancer Cells |
| PMC10383317__F3 | Neuroendocrine Effects on the Risk of Metabolic Syndrome in Children |
| PMC10383966__F1 | Pellino Proteins in Viral Immunity and Pathogenesis |
| PMC10383966__F4 | Pellino Proteins in Viral Immunity and Pathogenesis |
| PMC10383978__F3 | Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer |
| PMC10384200__F4 | Association between High Interferon-Gamma Production in Avian Tuberculin-Stimulated Blood from Mycobacterium avium subsp. paratuberculosis-Infected Cattle and Candidate Genes Implicated in Necroptosis |
| PMC10384322__F2 | Free Radical and Viral Infection: A Review from the Perspective of Ferroptosis |
| PMC10384352__F2 | Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections |
| PMC10384352__F3 | Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections |
| PMC10384366__F1 | Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells |
| PMC10384366__F11 | Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells |
| PMC10384495__F2 | Molecular and Genetic Interactions between Obesity and Breast Cancer Risk |
| PMC10384750__F1 | Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer |
| PMC10384750__F2 | Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer |
| PMC10384750__F3 | Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer |
| PMC10384750__F6 | Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer |
| PMC10384765__F6 | Exploring the Molecular Basis of Vesicular Stomatitis Virus Pathogenesis in Swine: Insights from Expression Profiling of Primary Macrophages Infected with M51R Mutant Virus |
| PMC10384840__F9 | Natural Flavonoids Quercetin and Kaempferol Targeting G2/M Cell Cycle-Related Genes and Synergize with Smac Mimetic LCL-161 to Induce Necroptosis in Cholangiocarcinoma Cells |
| PMC10385272__F5 | Key gene expression patterns in carbohydrate metabolism and lipid metabolism pathways in the pulp and seeds of Symplocos paniculate |
| PMC10385528__F3 | Anticancer mode of action of melittin on the essential molecular targets in different carcinomas |
| PMC10385841__F4 | Rotavirus interactions with the host innate immune system |
| PMC10385841__F5 | Top networks associated with lipid metabolism identified in PIEs infected with G9P[13] |
| PMC10385841__F6 | Top networks associated with lipid metabolism identified in PIEs infected with G5P |
| PMC10385932__F1 | Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies |
| PMC10385954__F13 | Putative mechanism of artemisinin neuroprotective action against 6-OHDA and MPP+-induced neuronal injury |
| PMC10387486__F4 | Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets |
| PMC10388466__F7 | Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NFKB activation via disrupting multiple-site ubiquitination of NEMO |
| PMC10388482__F9 | SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression |
| PMC10388552__F6 | Aberrations in ion channels interacting with lipid metabolism and epithelial–mesenchymal transition in esophageal squamous cell carcinoma |
| PMC10388730__F6 | Influence of cold-stimulated adipocyte supernatant on the expression of adhesion-related molecules in Schwann cell line |
| PMC10389819__F6 | C-Phycocyanin Ameliorates the Senescence of Mesenchymal Stem Cells through ZDHHC5-Mediated Autophagy via PI3K/AKT/mTOR Pathway |
| PMC10389822__F2 | Intersection of COVID-19 and Rheumatoid Arthritis: Shared Mechanisms, Treatment Challenges, and Potential Therapeutic Approaches |
| PMC10389832__F1 | CGAS-STING in Age-Related Diseases from Mechanisms to Therapies |
| PMC10389832__F4 | CGAS-STING in Age-Related Diseases from Mechanisms to Therapies |
| PMC10389837__F3 | Research Progress on the Etiology and Pathogenesis of Alzheimer's Disease from the Perspective of Chronic Stress |
| PMC10390051__F3 | Enteric nervous system as a target and source of SARS-CoV-2 and other viral infections |
| PMC10390225__F2 | Mononuclear phagocyte system in IgA nephropathy: pathogenesis and prognosis |
| PMC10390316__F1 | Cellular mechanisms of fibrin (ogen): insight from neurodegenerative diseases |
| PMC10394732__F2 | Mechanisms involved in mutant p53 exerting GOF effects |
| PMC10398793__F4 | In the IPA data software the disease and function analysis of the RNA sequencing data from Primbio |
| PMC10407612__F8 | Ghrelin in promotion of ADMSCs cardiomyocyte differentiation |
| PMC10411462__F8 | Function and mechanism of PARP inhibitor in thyroid cancers |
| PMC10411465__F2 | Gut microbiota-derived metabolites in AAD |
| PMC10411465__F3 | Major amino acid metabolic pathway involves AAD |
| PMC10411465__F4 | Alterations of polyunsaturated fatty acids metabolic pathways in AAD |
| PMC10413047__F2 | LncRNAs regulating the proliferation and apoptosis of NSCLC |
| PMC10413047__F3 | CASC9 and lncRNA UCA1 in drug resistance in NSCLC |
| PMC10417115__F2 | miRNA binding sites at the rs8720 and rs12587 variants of the KRAS gene and their function in tumor regulation |
| PMC10417163__F2 | Signaling pathways play an essential role in organizing the Golgi apparatus and maintaining neuronal polarity during neurogenesis |
| PMC10417430__F4 | Interruption of p53-MDM2 Interaction by Nutlin-3a in Human Lymphoma Cell Models Initiates a Cell-Dependent Global Effect on Transcriptome and Proteome Level |
| PMC10417430__F8 | Synergistic effect of N3a with HSPs and mTOR inhibitors in lymphoma cells: Summary of the therapeutic scheme followed in our study, with major findings highlighted in bold |
| PMC10417677__F3 | Anti-inflammatory mechanism of MBPs |
| PMC10417792__F1 | The MET signaling pathway and the sites of action for MET targeted therapies |
| PMC10418437__F1 | Signaling pathways activated by free mtDNA in the pathogenesis of metabolic syndrome |
| PMC10418475__F1 | Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects |
| PMC10418609__F8 | Expression of the DBNDD1 signaling pathway in prostate cancer (MetaCore) |
| PMC10418722__F12 | Study on the Regulation Mechanism of Quality Deterioration Due to Chilling Stress and Dry Exposure during Anhydrous Storage and Transportation of Yesso Scallop Patinopecten yessoensis |
| PMC10418793__F6 | Major pathways involved in retinal inflammation |
| PMC10418884__F10 | Regulatory pathway of GR |
| PMC10418941__F2 | Molecular crosslinks produced by the interaction of the HSCs and LSCs |
| PMC10418941__F3 | LSCs’ microenvironment in relation to epigenetic modification |
| PMC10418941__F4 | LSCs mechanism that employs fat as fuel |
| PMC10419059__F2 | Insulin and IGF-1 signalling pathway |
| PMC10419059__F3 | Wnt/Beta-catenin signalling pathway |
| PMC10419152__F1 | MAPK signaling pathways in mammalian cells: The MAPK signaling pathways are mediated by highly conserved MAPKs, which are activated sequentially |
| PMC10419152__F2 | Mammalian MAPK pathways by effector proteins: This figure depicts the various components of MAPK pathways targeted by the bacterial effector proteins |
| PMC10419312__F2 | Macrophages in CTD-ILD |
| PMC10419312__F3 | Agents to target macrophages in CTD-ILD |
| PMC10419760__F1 | TLR2 MyD88-dependent signaling pathway |
| PMC10419859__F2 | ATX/LPA signaling pathway in different inflammatory diseases |
| PMC10420029__F11 | Fanconi anemia pathway of P |
| PMC10420029__F12 | mTOR signaling pathway of P |
| PMC10420029__F8 | Transcription related pathways in the seminal tissues of P |
| PMC10420159__F1 | Immune checkpoints in a tumor microenvironment (TME) |
| PMC10420321__F8 | Molecular mechanism underlying the beneficial effects of FJE in the OVA-induced CARAS mouse model |
| PMC10421513__F10 | Structure Characterization and Immunomodulatory Activity of Misgurnus anguillicaudatus Carbohydrates |
| PMC10433440__F6 | (A and B) Illustration of classical and non-classical Wnt/Beta-catenin signaling pathways |
| PMC10439834__F1 | IL-17 signaling pathway: transduction and amplification |
| PMC10443056__F1 | Different interventions enhance nerve regeneration for the treatment of AD |
| PMC10447124__F8 | Mapping of Rap1 signaling pathway in NI vs |
| PMC10450211__F1 | An Illustration of the circRNAs that directly or through specific miRNA sponges activate the Wnt signaling pathway and play a role in the progression of lung cancer |
| PMC10450211__F2 | Circular RNAs: novel actors of Wnt signaling pathway in lung cancer progression |
| PMC10451182__F2 | Intrinsic and extrinsic apoptotic pathways and confirmed target genes of miR-106a |
| PMC10451232__F4 | Transcriptomic changes in p53-associated apoptotic signaling in burn-wound-healing pathway |
| PMC10451275__F3 | Changes in subcellular localization of Ras upon S-nitrosylation |
| PMC10451380__F1 | Scheme of the NRF2 signaling pathway |
| PMC10451660__F3 | AhR signaling pathway |
| PMC10451954__F1 | Primary Coenzyme Q10 Deficiency: An Update |
| PMC10451996__F12 | Mechanism by which fibroblast upregulation of VDR suppresses lung fibroblast proliferation and activation during pulmonary fibrosis |
| PMC10452344__F1 | Influence of microRNAs on the hippo signaling pathway in gliomas |
| PMC10452461__F2 | Fusobacterium affects chemotherapy drugs |
| PMC10452661__F1 | PI3K/AKT/mTOR pathway-related gene alterations involved in the pathogenesis of Endometriosis and Endometriosis-Associated Ovarian Cancer |
| PMC10452661__F2 | Crosstalk between IL-6 signaling and the PI3K/AKT/mTOR pathway in EAOC |
| PMC10452677__F1 | Relevance network of genes, transcription factors, small molecules, functional classes, miRNA, and biological processes that are shared between DMD and HMB (based on Pathway Studio Web Mammalian) |
| PMC10452754__F2 | The molecular interaction between HLA-G and decidual NK cells at the maternal–fetal interface |
| PMC10452836__F7 | Reconstructed network using StringDB of the dynamic interactome of KRASG12C (grey halo) in HEK293 cells identified in the AP-MS screen |
| PMC10453069__F1 | Clonal evolution of plasma cell dyscrasias |
| PMC10453069__F2 | ATM- and ATR-mediated pathways in the presence of damaged DNA |
| PMC10453069__F3 | Excision repair pathways of DNA single-strand breaks |
| PMC10453069__F4 | DNA repair pathways of DNA double-strand breaks |
| PMC10453169__F2 | Schematic model of the canonical HH signaling pathway |
| PMC10453169__F5 | Hedgehog Signaling Pathway in Head and Neck Squamous Cell Carcinoma |
| PMC10453317__F2 | GAB1 recruitment modes to activated receptors and major GAB1 signaling pathways |
| PMC10453365__F1 | Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling |
| PMC10453526__F2 | Nodes and tracks of the cholinergic anti-inflammatory pathway |
| PMC10453554__F1 | Cyclin K-CDK12/13 complexes affect important biological processes and contribute to cancer development by phosphorylating different targets |
| PMC10454035__F2 | Hedgehog (Hh) signaling pathway, normal and with Gorlin syndrome |
| PMC10454115__F4 | Mechanisms of Pi, Tf, Td, and Cr in AS |
| PMC10454149__F1 | MiRNA-146a—A Key Player in Immunity and Diseases |
| PMC10454149__F2 | MiRNA-146a—A Key Player in Immunity and Diseases |
| PMC10454149__F3 | MiRNA-146a—A Key Player in Immunity and Diseases |
| PMC10454457__F2 | Genes of the TLR signaling pathway observed in chicken thrombocytes |
| PMC10454457__F3 | Constitutively expressed genes of class I and II major histocompatibility complex processes of endogenous and exogenous antigen processing pathways found in chicken thrombocytes |
| PMC10454494__F3 | Prostate cancer pathways [112] |
| PMC10454639__F11 | Regulatory pathway map of roots suffering Mn poisoning in soybean |
| PMC10454700__F3 | Molecular Regulatory Mechanism in Multipotency and Differentiation of Wharton’s Jelly Stem Cells |
| PMC10454700__F4 | Molecular Regulatory Mechanism in Multipotency and Differentiation of Wharton’s Jelly Stem Cells |
| PMC10454712__F2 | Diagram of genes and metabolite pathways associated with the major secondary metabolites of tea plants |
| PMC10454862__F10 | S100A4 Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NFKB/NLRP3 Inflammasome Signaling Pathway |
| PMC10458348__F4 | Histone Modification of Colorectal Cancer by Natural Products |
| PMC10458543__F5 | Protein interaction network created using STRING database based on Bos taurus genome |
| PMC10458661__F2 | TLR and RLR signaling pathways present in airway epithelial cells in response to viral infections |
| PMC10458925__F1 | EGFR/PI3K/AKT/mTOR signaling pathway |
| PMC10458946__F6 | STING signaling pathway inhibition by STINGB in various ways and at various steps |
| PMC10459054__F1 | Typical pathway of miRNA formation |
| PMC10459054__F2 | Anti-cancer mechanisms of five agents (1) resveratrol induces growth inhibition and apoptosis in colon cancer DLD-1 cells by reducing miRNA-96 expression through MAPK/ERK1/2 signaling pathway activation |
| PMC10459054__F4 | Natural Products Treat Colorectal Cancer by Regulating miRNA |
| PMC10459190__F2 | Molecular mechanisms involved in atherogenic effects of Cd exposure |
| PMC10459248__F2 | Cellular pathways modulated by ASFV |
| PMC10459989__F5 | Schematic diagram of the plant hormone signal transduction pathway and its correlation with DEGs in response to B |
| PMC10463219__F6 | Resveratrol ameliorates insulin resistance by improving insulin signaling via the DDIT4/mTOR/IRS-1/PI3K/AKT/GLUT4 pathway |
| PMC10466072__F9 | Schematic diagram |
| PMC10467107__F7 | Cardiac Toxicity Induced by Long-Term Environmental Levels of MC-LR Exposure in Mice |
| PMC10468807__F1 | lncRNAs are involved in tumor cell lipid metabolism by targeting different signaling pathways |
| PMC10468808__F2 | Activation of NFKB and MAPK signaling pathways regulates the expression of catabolic factors |
| PMC10471462__F1 | Hippo pathway is a signaling pathway that regulates the self-renewal and differentiation of hematopoietic stem cells (HSCs) |
| PMC10471462__F2 | Hippo pathway is involved in T cell development |
| PMC10471462__F3 | Hippo pathway is involved in megakaryopoiesis (upper panel) and erythropoiesis (bottom panel) |
| PMC10472599__F8 | Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML |
| PMC10472646__F1 | Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application |
| PMC10472646__F3 | Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application |
| PMC10472888__F3 | GPX4 in cell death, autophagy, and disease |
| PMC10473100__F1 | Necroptosis and Alzheimer’s Disease: Pathogenic Mechanisms and Therapeutic Opportunities |
| PMC10473100__F3 | Necroptosis and Alzheimer’s Disease: Pathogenic Mechanisms and Therapeutic Opportunities |
| PMC10473115__F1 | Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease |
| PMC10473115__F2 | Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease |
| PMC10473115__F3 | Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease |
| PMC10473115__F4 | Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease |
| PMC10473144__F2 | Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer’s Disease |
| PMC10473144__F3 | Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer’s Disease |
| PMC10473147__F2 | Neuroinflammation: A Common Pathway in Alzheimer’s Disease and Epilepsy |
| PMC10473154__F1 | Understanding the Involvement of microRNAs in Mitochondrial Dysfunction and Their Role as Potential Biomarkers and Therapeutic Targets in Parkinson’s Disease |
| PMC10473156__F3 | DNA Damage Response-Associated Cell Cycle Re-Entry and Neuronal Senescence in Brain Aging and Alzheimer’s Disease |
| PMC10473922__F9 | Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NFKB pathway |
| PMC10473946__F1 | Impact of inhaled and intranasal corticosteroids on glucose metabolism and diabetes mellitus: A mini review |
| PMC10474042__F2 | Calcium signaling in efferocytosis |
| PMC10474047__F8 | Neurod1/4-Ntrk3-Src pathway regulates gonadotrope cell motility during gonadotrope differentiation |
| PMC10474053__F3 | PI3K-AKT pathway and major upstream effectors in the signaling network |
| PMC10474053__F5 | Dysregulation of Ca2+ channels and pumps in metabolic diseases |
| PMC10474053__F6 | Ca2+-mediated inhibition of membrane localization of PIP-binding proteins |
| PMC10474074__F2 | Kennedy pathway and Lands cycle in ferroptosis |
| PMC10474083__F1 | Detailed kinetic model of glycolysis in Plasmodium falciparum-infected red blood cells for antimalarial drug target identification |
| PMC10474093__F9 | Working model |
| PMC10474116__F3 | Pathways of mitochondrial quality control |
| PMC10474116__F4 | Apoptotic signaling pathways |
| PMC10474119__F9 | Mechanistic diagram summarizing the regulatory effect of TGR5 in mitochondrial dysfunction and neuroinflammation in Müller cells |
| PMC10474147__F14 | Mechanism underlying oxeiptosis |
| PMC10474147__F2 | Necrosis and apoptosis: morphological features and signaling pathways |
| PMC10474176__F6 | NEDD8-activating enzyme E1 UBA3 orchestrates the immunosuppressive microenvironment in lung adenocarcinoma via the NF-кB pathway |
| PMC10474200__F4 | Interconnectivity between prioritized high confidence transcription factors |
| PMC10474200__F5 | Prolactin signaling pathway |
| PMC10474437__F2 | Differentially expressed non-coding RNAs and their regulatory networks in liver cancer |
| PMC10474666__F4 | FBXW7 in breast cancer: mechanism of action and therapeutic potential |
| PMC10474740__F2 | Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization |
| PMC10474740__F3 | Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization |
| PMC10474743__F4 | Advances in immunotherapy for triple-negative breast cancer |
| PMC10474868__F1 | Polyhydroxylated Fullerene C60(OH)40 Nanofilms Promote the Mesenchymal–Epithelial Transition of Human Liver Cancer Cells via the TGFB1/Smad Pathway |
| PMC10475367__F2 | Kyoto Encyclopedia of Genes and Genomes pathway of target genes in CRC |
| PMC10476361__F6 | HDAC5 regulates MEF2A expression by influencing the ERK/EGR1 signaling pathwayVentricular remodeling induces cytoplasm translocation of HDAC5 |
| PMC10476430__F2 | Underlying upstream and downstream mechanisms of cardiokines that mediate the heart-to-adipose tissue communication |
| PMC10476815__F6 | Predicted targets of Ruxian Shuhou prescription in the PI3-Akt signaling pathway |
| PMC10478265__F1 | The cGAS-STING pathway in radiotherapy for non-small cell lung cancer |
| PMC10478265__F2 | The cGAS-STING pathway in radiotherapy for non-small cell lung cancer |
| PMC10478283__F8 | Mechanism diagram |
| PMC10478443__F4 | Functional enrichment analysis of IGF2BP1 regulated pathways in B-ALL |
| PMC10478470__F2 | HMGB1 and TLRs signaling pathway |
| PMC10478475__F8 | Hypothesized mechanism by which Ex-4 reduces tau hyperphosphorylation via Wnt/Beta-catenin/NeuroD1 signalling in T2D models |
| PMC10478613__F2 | Structure and function of kartogenin |
| PMC10478980__F1 | Process of necroptosis |
| PMC10478980__F4 | Process of apoptosis |
| PMC10480466__F7 | Lenvatinib inhibition of EMT in ICC cells |
| PMC10483736__F1 | Combining old and new concepts in targeting telomerase for cancer therapy: transient, immediate, complete and combinatory attack (TICCA) |
| PMC10483926__F7 | Illustration of a hypothetical model in which TgESPs regulate aerobic glycolysis to promote osteogenic differentiation through the Wnt/Beta-catenin signaling pathway |
| PMC10484181__F3 | Potential mechanism of P2X7R overexpression causing tumor progression |
| PMC10484649__F4 | Mitogen-activated protein kinase (MAPK) signal pathway in subchondral bone |
| PMC10484658__F2 | Schematic diagram of ERS in renal resident cells in LN |
| PMC10484938__F7 | Metabolic remodeling in the brain and liver following STF |
| PMC10485805__F1 | Intestinal flora regulates tumor microenvironment components |
| PMC10486522__F1 | Leptin and a schematic representation of leptin-induced signaling pathways |
| PMC10486522__F2 | Adiponectin and a schematic representation of adiponectin-induced signaling pathways |
| PMC10486640__F8 | Identification of the expression of key genes of the TLR signaling pathway |
| PMC10486691__F6 | Association of EN2 with ERBB, insulin, BCR-ABL and JAK signaling |
| PMC10486718__F1 | Schematically representing the signal transduction and biological activities induced by androgen in ER-positive breast cancer cells |
| PMC10486718__F2 | Schematically representing the signal transduction and biological activities induced by androgen in ER-negative breast cancer cells |
| PMC10486718__F3 | Diagram illustrating the androgen-mediated signal transduction via integrins and the resulting biological activities |
| PMC10486880__F4 | Anti-cancer mechanisms of leeks and their active compounds |
| PMC10487526__F9 | Proinflammatory immune response in BV-2 microglial cells induced by NfEVs |
| PMC10487821__F9 | Activation of the Wnt/Beta-catenin signaling pathway via lithium released from the IPN-Li hydrogel |
| PMC10487916__F3 | miRNA–mRNA network based on the target genes of miR-141-3p, miR-150-5p, miR-182-5p, and miR-661 (obtained from the Integrated Breast Cancer Pathway (Wikipathways)) |
| PMC10487928__F4 | Gamma interactome of the top 20 most connected differentially expressed genes (DEGs), defense response to virus genes, angiogenesis genes, adaptive and innate immune genes, and SARS-CoV-2 proteins |
| PMC10487928__F5 | Delta interactome of the top 20 most connected differentially expressed genes (DEGs), defense response to virus genes, angiogenesis genes, adaptive and innate immune genes, and SARS-CoV-2 proteins |
| PMC10487929__F10 | Network connectivity pathway map of ACE2’s downstream effects of simulated SARS-CoV-2 infection on predicted activity of the NISP |
| PMC10487929__F11 | Downstream effect analysis of molecules downstream ACE2 and upstream of the NISP in the network connectivity pathway map of ACE2’s downstream effects of simulated SARS-CoV-2 infection on predicted activity of SNCA and PD |
| PMC10487929__F6 | Influence of COVID-19 on SNCA expression and PD |
| PMC10487929__F7 | Network connectivity pathway map of ACE2’s downstream effects of simulated SARS-CoV-2 infection on predicted activity of SNCA and PD |
| PMC10487929__F9 | Network connectivity pathway map of the downstream effects of simulated SARS-CoV-2 infection on the predicted activity of the NISP |
| PMC10487967__F2 | CGAS–STING pathway in cell death, autophagy, and senescence |
| PMC10487967__F3 | Different roles of the cGAS–STING pathway in host defense and various diseases |
| PMC10488162__F3 | The Nrf2 signaling pathway in age-related ovarian aging |
| PMC10488162__F4 | The Nrf2 signaling pathway in environmental pollutant-related ovarian aging |
| PMC10488294__F3 | AML cell differentiation by S100A9 |
| PMC10489316__F10 | Targets-pathways network |
| PMC10489316__F9 | Details of KEGG pathways of Ras, PI3K-Akt, and MAPK signaling pathway |
| PMC10489547__F3 | Main signaling pathway of cell division cycle 20 homologue (CDC20) in cancers |
| PMC10489936__F4 | Polysaccharides modulate liver bile acids (BAs)-related signaling pathways of metabolic associated fatty liver disease (MAFLD) |
| PMC10490091__F7 | Anti-Inflammatory Effect of Meriania hexamera Sprague by Targeting Syk Kinase in NFKB Signaling |
| PMC10491753__F5 | Pictorial model of intracellular redox balance facilitated by compartmentalization of amino acid biosynthesis enzymes within optimally sized peroxisomes |
| PMC10492287__F9 | The metabolic pathway in placental cells |
| PMC10492386__F10 | EVs interacting with immune cells |
| PMC10493031__F3 | Schematic illustration of the CRC-derived exosome mechanisms for CRC metastasis |
| PMC10493031__F5 | Schematic illustration of key molecular signaling pathways in metastasis |
| PMC10494486__F7 | Signaling model for late-phase IP-10 induction by MRP8/14 in endotoxic mice |
| PMC10494518__F1 | Insulin signaling pathway |
| PMC10495336__F6 | Working model of the oncogenic potential of SGG UCN34 |
| PMC10495361__F5 | Joint analysis of Chinese yew seed transcriptome, proteome, and metabolome |
| PMC10495361__F6 | Summary diagram of specific metabolic pathways involved in Chinese yew seed germination |
| PMC10495745__F1 | Activation of the NF‐KB signaling pathway in macrophages |
| PMC10495745__F2 | Activation of the JAK‐STAT signaling pathway in macrophages |
| PMC10495745__F3 | Activation of PI3K/Akt and Notch signaling pathways in macrophages |
| PMC10495745__F4 | Activation of MAPK and TGF‐B‐SMAD signaling pathways in macrophages |
| PMC10495745__F5 | Activation of GPCR signaling pathway in macrophages |
| PMC10495754__F1 | RIPK3-CaMKII-mPTP signaling pathway |
| PMC10497558__F3 | BCAAs metabolism in Cancer |
| PMC10497558__F5 | Aspartate, Arginine and Methionine metabolism |
| PMC10497558__F6 | Aspartate metabolism in solid tumor |
| PMC10497558__F8 | Arginine metabolism in tumor cells |
| PMC10498433__F8 | Lactate-induced oxidative stress |
| PMC10498649__F2 | Lipid metabolic alterations induced by oncogenic events and TME cues |
| PMC10499775__F1 | Illustration of the Fas-FasL pathway |
| PMC10500222__F1 | CELF2 affects ferroptosis through the MAPK signalling pathway |
| PMC10500222__F2 | CELF2 affects ferroptosis through the PI3K/AKT signalling pathway |
| PMC10500222__F5 | CELF2 affects ferroptosis via the Wnt/Beta-catenin pathway |
| PMC10500222__F6 | CELF2 is the upstream regulation factor of MAPK signalling pathway, PI3K/AKT signalling pathway, autophagy and ERAD pathway, which can promote cancer cell ferroptosis through these pathways |
| PMC10501637__F5 | PPI network analysis of total DEGs in ELMOD3mut and ELMOD3corrected iPSCs |
| PMC10502012__F5 | Proposed mechanism for PHT1 mode of action |
| PMC10502204__F2 | ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma |
| PMC10502727__F1 | Basic research on chordoma |
| PMC10502988__F8 | Following CARNIVAL analysis (or re-uploading previous results) the user can carry out pathway enrichment and visualisation on the inferred signalling network |
| PMC10503159__F9 | Proposed model depicting the possible mechanism of bta-miR-223 on mediating inflammatory injuries and oxidative stress via regulation of NLRP3 inflammasome and Keap1/Nrf2 pathway |
| PMC10505163__F9 | Hallmarks of severe asthma and the possible role of the identified mRNAs by artificial intelligence methods |
| PMC10505224__F0 | By hindering hnRNPA2B1 from binding to the E3 ubiquitin ligase TRIM21, whose mediated ubiquitin-dependent degradation was thereby inhibited, CRNDE protected the stability of hnRNPA2B1’s high protein expression in CRC |
| PMC10505339__F1 | Interaction of Wnt/Beta-catenin and Wnt/Ca2+ signalling pathways in an inflammatory environment |
| PMC10505339__F2 | NFKB signalling pathway |
| PMC10505339__F4 | BMP signalling pathway |
| PMC10505605__F1 | Extranodal lymphoma: pathogenesis, diagnosis and treatment |
| PMC10506040__F2 | Schematic representation showing downstream signaling events in cross-talk between adiponectin signal transduction and insulin signaling pathway[67] |
| PMC10506215__F3 | PTM of PGK1, including acetylation, phosphorylation, ubiquitination and O-GlcNAcylation |
| PMC10506243__F5 | Protein-protein interaction network and functional enrichment analysis of proteins with acetylation, carbamylation and phosphorylation sites regulated by bacterial lipopolysaccharide (LPS) |
| PMC10506410__F1 | MTOR Signaling Network (A) Overview of the mTOR signaling pathway (B–D) mTORC1 signaling in mRNA translation, metabolism, and protein turnover (E) mTORC2 signaling function |
| PMC10506410__F3 | Vitamin D receptor deficiency may induce alopecia through the Ddit4/mTOR signaling pathway |
| PMC10506516__F6 | Schematics of proposed pathway for beneficial effects of L-carnitine on lipid parameters |
| PMC10507626__F2 | Molecular mechanism of inducing cognitive impairment in OSA patients through intermittent hypoxia (IH) |
| PMC10507829__F1 | Extracellular matrix-induced signaling pathways in mesenchymal stem/stromal cells |
| PMC10507829__F4 | Illustration of contributing factors of the signaling pathway for DDR1 in human adipose-derived MSC (A), (B), (C), which generated using ReactomeFIPlugIn in Cytoscape (B and C—enlarged parts of the image A) |
| PMC10508215__F1 | AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3B,17Beta-Diol |
| PMC10508518__F5 | KEGG simulated signaling pathway analysis |
| PMC10509026__F1 | Schematic view of vitamin D (VD) signaling pathway mediated VD receptor (VDR) |
| PMC10510267__F8 | MCL’s protection against PD-related peritoneal fibrosis |
| PMC10511167__F7 | MiR-143/145 cluster induced by TGFB1 suppresses Wilms’ tumor 1 expression in cultured human podocytes |
| PMC10511904__F3 | Diagram illustrates how IMD activates various downstream signaling pathways through different CLR/RAMP receptor complexes |
| PMC10511911__F5 | Regulation of insecticide resistance mechanisms involves epi-transcriptome signals, detoxification signaling pathways, and long non-coding RNAs (lncRNAs) |
| PMC10512452__F6 | IL-10 Exerts anti-inflammatory effects through STAT3 signaling pathway |
| PMC10512581__F1 | Hippo signaling pathway and therapeutic targets |
| PMC10513393__F5 | Cytokine-mediated signaling in T-cell lymphoma metabolic reprogramming |
| PMC10513492__F7 | Lipid and atherosclerosis and (B) AGE-RAGE signaling pathway in diabetic complications map of Chaihu Anxin Capsule for their potential treatment of depression |
| PMC10514503__F2 | S1P maintains the intestinal intraepithelial EC barrier |
| PMC10514503__F3 | S1P protects the intestinal barrier through multiple means |
| PMC10514522__F2 | Microglial metabolism shifts from OXPHOX to glycolysis in the inflammatory state |
| PMC10514522__F3 | Lipid metabolism in microglia in the inflammatory state |
| PMC10515252__F4 | m6A modifications interact with the CRC inflammatory microenvironment |
| PMC10516898__F15 | Mechanism of D-TT-BMSCs inhibiting ferroptosis to repair the wound |
| PMC10517567__F8 | Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression |
| PMC10518103__F9 | DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress |
| PMC10518396__F7 | Overcoming the therapeutic limitations of EZH2 inhibitors in Burkitt’s lymphoma: a comprehensive study on the combined effects of MS1943 and Ibrutinib |
| PMC10518420__F3 | An emerging research: the role of hepatocellular carcinoma-derived exosomal circRNAs in the immune microenvironment |
| PMC10518439__F2 | Pyroptosis and inflammasomes in cancer and inflammation |
| PMC10519146__F10 | Intracellular innate immune response to avian influenza |
| PMC10519225__F5 | Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles |
| PMC10519534__F8 | DZP active constituents on myopia through the “AGE-RAGE diabetic complication signaling” pathway |
| PMC10520073__F7 | Graphical representation of the regulation mechanism underlying ABC variant rs4810856 and CRC risk |
| PMC1052008__F1 | Activation of PI3K/Akt signaling in adaptive versus maladaptive hypertrophy |
| PMC1052008__F3 | GSK-3 as a convergence point in hypertrophic signaling |
| PMC10520362__F3 | Mammalian Intestinal Development and Differentiation—The State of the Art |
| PMC10520536__GA1 | Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the Wnt/Beta-catenin signaling pathway |
| PMC10520667__F7 | LncRNA DLX6-AS1/miR-16-5p axis regulates autophagy and apoptosis in non-small cell lung cancer: A Boolean model of cell death |
| PMC10520679__F1 | Exosomal non-coding RNAs: Blueprint in colorectal cancer metastasis and therapeutic targets |
| PMC10520679__F3 | An illustration demonstrates the involvement of ncRNAs and oncogenic signaling pathways in CRC metastasis |
| PMC10520719__F11 | ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer |
| PMC10520786__F2 | Nrf2-mediated therapeutic effects of dietary flavones in different diseases |
| PMC10520786__F3 | Nrf2 modulates inflammation and apoptosis |
| PMC10520882__F7 | Biased M3 mAChR ligand PD 102807 mediates qualitatively distinct signaling to regulate airway smooth muscle phenotype |
| PMC10520887__F9 | Porcine IKKE is involved in the STING-induced type I IFN antiviral response of the cytosolic DNA signaling pathway |
| PMC10520974__F3 | Noncoding RNAs as an emerging resistance mechanism to immunotherapies in cancer: basic evidence and therapeutic implications |
| PMC10520974__F4 | Regulatory mechanisms of lncRNAs in cancer cell antigen presentation |
| PMC10520974__F7 | Noncoding RNAs as an emerging resistance mechanism to immunotherapies in cancer: basic evidence and therapeutic implications |
| PMC10521506__F10 | Milk thistle nano-micelle formulation promotes cell cycle arrest and apoptosis in hepatocellular carcinoma cells through modulating miR-155-3p /SOCS2 /PHLDA1 signaling axis |
| PMC10521544__F4 | Luteolin-target-pathway network |
| PMC10521544__F6 | Network pharmacology and experimental verification-based strategy for exploring the mechanisms of luteolin in the treatment of osteosarcoma |
| PMC10522371__F7 | KIF18A improves migration and invasion of colorectal cancer (CRC) cells through inhibiting PTEN signaling |
| PMC10522861__F7 | Analysis of the response mechanisms of Pinellia ternata to terahertz wave stresses using transcriptome and metabolic data |
| PMC10522874__F2 | Mature white adipocyte plasticity during mammary gland remodelling and cancer |
| PMC10522995__F1 | CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF1 |
| PMC10523190__F1 | Progress in the research of cuproptosis and possible targets for cancer therapy |
| PMC10523328__F2 | Tactile twist: decoding the phenomena of mechanical itch and alloknesis |
| PMC10523725__F7 | Gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis |
| PMC10525124__F2 | Oxidative Stress in Liver Pathophysiology and Disease |
| PMC10525260__F3 | Multi-Faceted Role of Cancer-Associated Adipocytes in Colorectal Cancer |
| PMC10525272__F4 | Vascular smooth muscle contraction pathway confirmed in the KEGG pathway analysis |
| PMC10525272__F5 | Canine Somatic Mutations from Whole-Exome Sequencing of B-Cell Lymphomas in Six Canine Breeds—A Preliminary Study |
| PMC10525272__F6 | Platelet activation pathway confirmed in the KEGG pathway analysis |
| PMC10525295__F1 | Review of the Relationship between the Immune Response, Inflammation, Oxidative Stress, and the Pathogenesis of Sickle Cell Anaemia |
| PMC10525362__F1 | Calcium, Phosphorus and Magnesium Abnormalities Associated with COVID-19 Infection, and Beyond |
| PMC10525517__F2 | RUNX1-Regulated Signaling Pathways in Ovarian Cancer |
| PMC10525526__F1 | Phenotype Alterations in the Cecal Ecosystem Involved in the Asymptomatic Intestinal Persistence of Paratyphoid Salmonella in Chickens |
| PMC10525531__F7 | High Hepcidin Levels Promote Abnormal Iron Metabolism and Ferroptosis in Chronic Atrophic Gastritis |
| PMC10525532__F4 | Thioredoxin/Glutaredoxin Systems and Gut Microbiota in NAFLD: Interplay, Mechanism, and Therapeutical Potential |
| PMC10525645__F1 | Abnormalities in Copper Status Associated with an Elevated Risk of Parkinson’s Phenotype Development |
| PMC10525645__F2 | Simplified scheme for the conversion of food-derived copper into biovaluable copper |
| PMC10525672__F3 | Stress Urinary Incontinence: An Unsolved Clinical Challenge |
| PMC10525949__F6a | Transcriptomics Reveal the Effects of Breeding Temperature on Growth and Metabolism in the Early Developmental Stage of Platax teira |
| PMC10525998__F10 | Transcriptomic Analysis of Light-Induced Genes in Nasonia vitripennis: Possible Implications for Circadian Light Entrainment Pathways |
| PMC10526115__F3 | Why Is Iron Deficiency/Anemia Linked to Alzheimer’s Disease and Its Comorbidities, and How Is It Prevented? |
| PMC10526140__F4 | Understanding the Clinical Use of Levosimendan and Perspectives on its Future in Oncology |
| PMC10526161__F1 | Integrated Multi-Omics Profiling of Young Breast Cancer Patients Reveals a Correlation between Galactose Metabolism Pathway and Poor Disease-Free Survival |
| PMC10526229__F1 | Notch Signaling by Small-Molecular Compounds and Its Potential in Anticancer Studies |
| PMC10526236__F4 | MicroRNAs in the Regulation of RIG-I-like Receptor Signaling Pathway: Possible Strategy for Viral Infection and Cancer |
| PMC10526250__F1 | Changes in the Acetylcholinesterase Enzymatic Activity in Tumor Development and Progression |
| PMC10526262__F2 | Importance of M1-and M2-Polarized Macrophages in Glioma and as Potential Treatment Targets |
| PMC10526343__F1 | Comprehensive Review on Neuroimmunology: Insights from Multiple Sclerosis to Future Therapeutic Developments |
| PMC10526378__F1 | Angiogenesis in Lung Cancer: Understanding the Roles of Growth Factors |
| PMC10526378__F3 | Angiogenesis in Lung Cancer: Understanding the Roles of Growth Factors |
| PMC10526380__F3 | Molecular Classifiers in Skin Cancers: Challenges and Promises |
| PMC10526485__F2 | Mitochondrial Calcium Uniporter (MCU): Molecular Identity and Role in Human Diseases |
| PMC10526530__F2 | What General Neurologists Should Know about Autoinflammatory Syndromes? |
| PMC10526800__F3 | Diverse Roles of Protein Palmitoylation in Cancer Progression, Immunity, Stemness, and Beyond |
| PMC10526805__F2 | Phosphoinositide Signaling by Scaffolds at Cytoplasmic Membranes |
| PMC10526805__F3 | Phosphoinositide Signaling by Scaffolds at Cytoplasmic Membranes |
| PMC10526836__F1 | Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential |
| PMC10526871__F3 | Nuclear Estrogen Receptors in Prostate Cancer: From Genes to Function |
| PMC10526873__F1 | G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology |
| PMC10526873__F2 | G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology |
| PMC10527059__F4 | Predicted function of miRNAs interacting with circPSEN1s is summarized in this picture |
| PMC10527059__F8 | Presenilin-1-Derived Circular RNAs: Neglected Epigenetic Regulators with Various Functions in Alzheimer’s Disease |
| PMC10527326__F2 | The Biomarkers, Molecular Targets and Mechanisms of Non-Alcoholic Steatohepatitis-Driven Hepatocarcinogenesis |
| PMC10527328__F1 | Exploring the Molecular Landscape of Myelofibrosis, with a Focus on Ras and Mitogen-Activated Protein (MAP) Kinase Signaling |
| PMC10527779__F3 | Biochemical and Molecular Pathways in Neurodegenerative Diseases: An Integrated View |
| PMC10527795__F1 | Wnt signaling pathway |
| PMC10528086__F1 | When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex |
| PMC10528086__F2 | When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex |
| PMC10528301__F3 | An Overview of CD133 as a Functional Unit of Prognosis and Treatment Resistance in Glioblastoma |
| PMC10528430__F1 | Microglial responses in Alzheimer’s Disease |
| PMC10528641__F2 | Regulatory Mechanisms That Guide the Fetal to Postnatal Transition of Cardiomyocytes |
| PMC10528955__F1 | Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer’s disease, and Depression |
| PMC10529739__F3 | Signalling pathways and transcription factors involved in MSC senescence |
| PMC10529747__F3 | TGFB as A Master Regulator of Aging-Associated Tissue Fibrosis |
| PMC10529750__F6 | Oxidative Stress in Multiple Exercise-Regulated Bone Homeostasis |
| PMC10529884__F1 | Report from the 24th Annual Western Canadian Gastrointestinal Cancer Consensus Conference on Colorectal Cancer, Richmond, British Columbia, 28–29, October 2022 |
| PMC10530375__F3 | Anti-Inflammatory Effects of Peripheral Dopamine |
| PMC10530385__F1 | Tet1 regulates pathways responding to PM2.5-induced oxidative stress |
| PMC10530547__F3 | Transcription Factor Zbtb20 as a Regulator of Malignancy and Its Practical Applications |
| PMC10530558__F1 | Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells |
| PMC10530558__F2 | Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells |
| PMC10530558__F6 | Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells |
| PMC10530615__F1 | Starving the Beast: Limiting Coenzyme A Biosynthesis to Prevent Disease and Transmission in Malaria |
| PMC10530616__F15 | Schematic illustration for the effects of Actinidia deliciosa (kiwi) extract on pathways related to T2DM |
| PMC10530670__F5 | Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Apoptosis, TNF Alpha and Interferon Gamma Response Gene mRNA Expression in T Lymphocytes |
| PMC10530696__F1 | Deciphering the Enigmatic Influence: Non-Coding RNAs Orchestrating Wnt/Beta-Catenin Signaling Pathway in Tumor Progression |
| PMC10530916__F8 | Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer |
| PMC10530945__F1 | Remodeling of Tumor Microenvironment by Nanozyme Combined cGAS–STING Signaling Pathway Agonist for Enhancing Cancer Immunotherapy |
| PMC10530962__F2 | Progress in Regenerative Medicine: Exploring Autologous Platelet Concentrates and Their Clinical Applications |
| PMC10531003__F2 | Pathway from Acute Kidney Injury to Chronic Kidney Disease: Molecules Involved in Renal Fibrosis |
| PMC10531041__F2 | Stress Response in Autophagy Processes and Aging-Related Diseases |
| PMC10531058__F1 | Lnc-RNAs in the Pathogenesis and Development of Diabetic Retinopathy |
| PMC10531058__F2 | SIRTI 1 pathway |
| PMC10531058__F4 | TGFB pathway |
| PMC10531058__F5 | Nuclear factor erythroid 2 related factor 2 (NRF2) pathway |
| PMC10531065__F8 | Antitumor Effect of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomics Approach |
| PMC10531073__F3 | Fluconazole-Induced Protein Changes in Osteogenic and Immune Metabolic Pathways of Dental Pulp Mesenchymal Stem Cells of Osteopetrosis Patients |
| PMC10531214__F3 | Exploring the JAK/STAT Signaling Pathway in Hepatocellular Carcinoma: Unraveling Signaling Complexity and Therapeutic Implications |
| PMC10531214__F4 | Exploring the JAK/STAT Signaling Pathway in Hepatocellular Carcinoma: Unraveling Signaling Complexity and Therapeutic Implications |
| PMC10531306__F2 | Exon 3-Deleted Growth Hormone Receptor (d3GHR) Polymorphism—A Favorable Backdoor Mechanism for the GHR Function |
| PMC10531420__F6 | Seasonal Developing Xylem Transcriptome Analysis of Pinus densiflora Unveils Novel Insights for Compression Wood Formation |
| PMC10531449__F3 | Transcriptomics of Canine Inflammatory Mammary Cancer Treated with Empty Cowpea Mosaic Virus Implicates Neutrophils in Anti-Tumor Immunity |
| PMC10531451__F6 | Heatmap of DEPs participated in the mevalonate (MEV) and methylerythritol phosphate (MEP) pathways of terpenoid biosynthesis |
| PMC10531730__F1 | Depiction of Branched-Chain Amino Acids (BCAAs) in Diabetes with a Focus on Diabetic Microvascular Complications |
| PMC10531820__F6 | Regulatory T Cells in Cancer Treatment Resistance |
| PMC10531837__F1 | Melanin production |
| PMC10531837__F2 | Exploring the Complex and Multifaceted Interplay between Melanoma Cells and the Tumor Microenvironment |
| PMC10531837__F4 | Phenotype switching in melanoma |
| PMC10531892__F8 | Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC Patients |
| PMC10531892__F9 | Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC Patients |
| PMC10532049__F1 | Angiogenesis—An Emerging Role in Organ Fibrosis |
| PMC10532080__F8 | Knockdown of BAP31 Downregulates Galectin-3 to Inhibit the Wnt/Beta-Catenin Signaling Pathway to Modulate 5-FU Chemosensitivity and Cancer Stemness in Colorectal Cancer |
| PMC10532123__F6 | Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells |
| PMC10532319__F7 | Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS–Mediated Signaling in Colorectal Cancer Cell Lines |
| PMC10532419__F3 | LOXL2 in Cancer: A Two-Decade Perspective |
| PMC10532419__F4 | LOXL2 in Cancer: A Two-Decade Perspective |
| PMC10532491__F2 | Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer |
| PMC10532491__F3 | Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer |
| PMC10532491__F5 | EGFR signal transduction pathway—an overview (modified after [94]) |
| PMC10533046__F3 | Recent Advances in the Biosynthesis of Natural Sugar Substitutes in Yeast |
| PMC10533267__F7 | sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway |
| PMC10534279__F3 | Growth differentiation factor 15 in cancer cachexia (Review) |
| PMC10534279__F4 | Growth differentiation factor 15 in cancer cachexia (Review) |
| PMC10534417__F1 | Putative biosynthesis pathway of limonin |
| PMC10534675__F1 | Recent Advances in the Treatment of Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases |
| PMC10534731__F2 | Possible Mechanisms of Dark Tea in Cancer Prevention and Management: A Comprehensive Review |
| PMC10534805__F9 | Lonicera Caerulea Juice Alleviates Alcoholic Liver Disease by Regulating Intestinal Flora and the FXR-FGF15 Signaling Pathway |
| PMC10534826__F2 | Impact of Opioids on Cellular Metabolism: Implications for Metabolic Pathways Involved in Cancer |
| PMC10534925__F3 | Epidermal Growth Factor Receptor-Targeted Neoantigen Peptide Vaccination for the Treatment of Non-Small Cell Lung Cancer and Glioblastoma |
| PMC10534927__F3 | Could Natural Products Help in the Control of Obesity? Current Insights and Future Perspectives |
| PMC10534981__F1 | Biomedical engineering approaches for the delivery of JAGGED1 as a potential tissue regenerative therapy |
| PMC10535041__F5 | Antagonistic Activity of Oroxylin A against Fusariumxa0graminearum and Its Inhibitory Effect on Zearalenone Production |
| PMC10535221__F7 | HAs induced LoVo cell apoptosis and inhibited the phosphorylation of Akt |
| PMC10535706__F8 | Akkermansia muciniphila inhibits tryptophan metabolism via the AhR/Beta-catenin signaling pathway to counter the progression of colorectal cancer |
| PMC10535809__F2 | Host and HBV Interactions and Their Potential Impact on Clinical Outcomes |
| PMC10535870__F9 | Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats |
| PMC10536053__F3 | Targeting DNA Damage Repair and Immune Checkpoint Proteins for Optimizing the Treatment of Endometrial Cancer |
| PMC10536053__F4 | Targeting DNA Damage Repair and Immune Checkpoint Proteins for Optimizing the Treatment of Endometrial Cancer |
| PMC10536099__F6 | Interferon-λ Activates a Differential Response in Peripheral Neurons That Is Effective against Alpha Herpesvirus Infections |
| PMC10536258__F2 | Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke |
| PMC10536258__F3 | Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke |
| PMC10536292__F9 | Theabrownin from Dark Tea Ameliorates Insulin Resistance via Attenuating Oxidative Stress and Modulating IRS-1/PI3K/Akt Pathway in HepG2 Cells |
| PMC10536424__F3 | Anti-cancer mechanisms of PDE5 inhibitors |
| PMC10536747__F2 | Liver and Muscle Transcriptomes Differ in Mid-Lactation Cows Divergent in Feed Efficiency in the Presence or Absence of Supplemental Rumen-Protected Choline |
| PMC10536768__F2 | Innate Immune Response to Viral Vectors in Gene Therapy |
| PMC10536768__F3 | Innate Immune Response to Viral Vectors in Gene Therapy |
| PMC10536768__F4 | Innate Immune Response to Viral Vectors in Gene Therapy |
| PMC10537080__F2 | Critical role of platelet in cancer progression and metastasis |
| PMC10537261__F3 | Ghrelin as a Biomarker of “Immunometabolic Depression” and Its Connection with Dysbiosis |
| PMC10537408__F8 | miRNAs in the HSV-2 infection of macrophages |
| PMC10537413__F4 | Unraveling MYC’s Role in Orchestrating Tumor Intrinsic and Tumor Microenvironment Interactions Driving Tumorigenesis and Drug Resistance |
| PMC10537516__F1 | IL-15 and N-803 for HIV Cure Approaches |
| PMC10537735__F10 | Modified Curcuminoid-Rich Extract Liposomal CRE-SDInhibits Osteoclastogenesis via the Canonical NFKB Signaling Pathway |
| PMC10537781__F9 | African swine fever virus I10L protein inhibits the NFKB signaling pathway by targeting IKKB |
| PMC10537991__F4 | Quantitative Differences in Rumen Epithelium Proteins in Lambs Fed Wheat, Perennial Wheat, or Perennial Wheat plus Lucerne |
| PMC10538272__F5 | Irreversible repolarization of tumour‐associated macrophages by low‐Pi stress inhibits the progression of hepatocellular carcinoma |
| PMC10538533__F1 | Updated roles of cGAS-STING signaling in autoimmune diseases |
| PMC10538549__F1 | cGAS-STING signaling pathway in intestinal homeostasis and diseases |
| PMC10538549__F2 | cGAS-STING signaling pathway in intestinal homeostasis and diseases |
| PMC10538549__F3 | cGAS-STING signaling pathway in intestinal homeostasis and diseases |
| PMC10538627__F1 | Research progress on the role of the Wnt signaling pathway in pituitary adenoma |
| PMC10538627__F2 | Research progress on the role of the Wnt signaling pathway in pituitary adenoma |
| PMC10538757__F2 | STRING analysis of protein–protein interactions |
| PMC10539095__F2 | Molecular Basis of Wnt/Beta-Catenin Signaling Pathways in Neurodegenerative Diseases |
| PMC10539319__F1 | Systemic iron sources and metabolism |
| PMC10539319__F3 | Testicular iron metabolism and ferroptosis |
| PMC10539544__F1 | GLUL gene knockdown and restricted glucose level show synergistic inhibitory effect on the luminal subtype breast cancer MCF7 cells’ proliferation and metastasis |
| PMC10539668__F8 | TNFA counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes |
| PMC10539698__F3 | Emerging roles of metabolism in the crosstalk between breast cancer cells and tumor-associated macrophages |
| PMC10539878__F3 | Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease |
| PMC10539942__F1 | Ferroptosis in effects of anesthetics on multiple organ diseases: A literature review |
| PMC10539948__F1 | IFNG signalling pathway |
| PMC10539950__F2 | Innate immune signalling in response to cytosolic DNA and DNA damage |
| PMC10540075__F8 | Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights |
| PMC10540234__F8 | Sulforaphane and bladder cancer: a potential novel antitumor compound |
| PMC10540332__F7 | Combined transcriptomic and metabolomic analysis of alginate oligosaccharides alleviating salt stress in rice seedlings |
| PMC10540347__F10 | SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3B signaling pathway through P53 |
| PMC10540449__F1 | BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications |
| PMC10540449__F3 | BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications |
| PMC10540449__F4 | BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications |
| PMC10540641__F9 | Schematic representing the manufacturing process of a targeted delivery system |
| PMC10540768__F2 | Unleashing the power of complement activation: unraveling renal damage in human anti-glomerular basement membrane disease |
| PMC10540835__F1 | Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe? |
| PMC10541724__F7 | Schematic illustration showing that CSSC-EVs mediated the LESC phenotype by regulating the Notch1 pathway through miRNAs |
| PMC10542901__F1 | Endothelium as initiator and target of type I IFN responses |
| PMC10542959__F3 | FOXM1 is involved in regulation of diabetes-related inflammatory responses |
| PMC10542959__F4 | FOXM1 may be involved in diabetic nephropathy by regulating signaling pathways such as NFKB/NLRP3 and Wnt/Beta-catenin |
| PMC10544979__F8 | The MyD88 and TRIF signaling pathways and downstream responses by the protein-based adjuvants rSIP and FLH in APCs |
| PMC10545718__F1 | Bioactive lipid-mediated regulation of insulin downstream signaling and lipid metabolism in adipocytes: mechanistic overview |
| PMC10545718__F2 | Genetic deletion of lipid biosynthetic and metabolic enzymes on adipocyte metabolism |
| PMC10545783__F1 | Bacterial PSAs transduce signals through innate receptors to modulate immune responses |
| PMC10545798__F1 | Landscape of cholesterol homeostasis regulation |
| PMC10545798__F6 | Internal and external factor regulation of cholesterol metabolism |
| PMC10545798__F8 | Cholesterol affects tumor cells by modulating immune responses, ferroptosis, tumor cell stemness, and the DNA damage response |
| PMC10546030__F2 | Methionine biosynthesis and metabolism: Diagram of metabolic pathway showing aspartate family pathway, metabolism of methionine and cysteine biosynthesis |
| PMC10546379__F4 | SIK1 inhibits tumor cell EMT by suppressing Beta-catenin signaling pathway and the expression of Twist 1 |
| PMC10546379__F7 | SIK2 on Wnt/Beta-catenin signaling pathway |
| PMC10548138__F1 | Transduction and regulatory pathways of PI3K/Akt pathway |
| PMC10548138__F2 | PI3K /Akt in COPD regulation |
| PMC10548218__F1 | FGF effects in breast cancer cells |
| PMC10550586__F4 | Representation of the KEGG TNF Signaling Pathway, showing up-regulated (red boxes) and down-regulated (green boxes) genes |
| PMC10551140__F7 | Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway |
| PMC10551637__F1 | Targets and applications of nanodrug targeting myeloid cells in osteosarcoma for the enhancement of immunotherapy |
| PMC10551897__F11 | KEGG pathway diagram for PI3K-AKT signalling pathway |
| PMC10551897__F12 | KEGG pathway diagram for EGFR tyrosine kinase inhibitor resistance pathway |
| PMC10551897__F13 | KEGG pathway diagram for MAPK signalling pathway |
| PMC10551897__F8 | SX Components-Targets-Pathways Network (Green hexagon node shows SX, pink diamond nodes show the components, blue rectangle nodes show target genes, orange ellipse-shape nodes show pathways and edges show the interaction between two nodes) |
| PMC10551897__F9 | SX Components-top 8 Targets-Pathways Network (Green hexagon node shows SX, pink circle nodes show the components, purple rectangle nodes show target genes, orange V-shape nodes show pathways and edges show the interaction between two nodes) |
| PMC10552298__F1 | , Hypothetical VOC production pathway originated from lipid peroxidation of membrane lipids |
| PMC10552500__F3 | Nutraceutical-mediated signaling pathways underlying some neuroprotective processes |
| PMC10552637__F1 | Metabolic cycle of tetrahydrofolate (THF) and the one-carbon (C1) metabolic pathway |
| PMC10552782__F2 | Regulatory Mechanism of Iguratimod on Signaling Pathway (IFN, interferon; TNF, Tumor necrosis factor; IL, Interleukin; Th, helper T cells; Treg, Regulatory T cells) |
| PMC10555535__F1 | Metabolic pathway of exogenous and endogenous lipoproteins |
| PMC10555542__F4 | Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial |
| PMC10556370__F3 | Mechanisms underlying TAX-mediated neuroprotection against AD or CAA |
| PMC10556387__F1 | Neuroprotection targeted to oxidative stress and induced mitochondrial dysfunction and ferroptosis in ischemic stroke |
| PMC10556387__F2 | Neuroprotection targeting to signal transduction of apoptosis, necroptosis, and autophagy in ischemic stroke |
| PMC10556522__F1 | Pathogenic signaling pathways in ALK+ ALCL () represents deregulated T-cell receptor signaling pathways mediated by NPM::ALK |
| PMC10556522__F2 | Genomic rearrangements that contribute to pathogenesis of ALK- ALCL () represents ALK- ALCL harboring DUSP22-rearrangement and associated signaling pathways |
| PMC10556577__F1 | TGFB signaling pathways (Activin and Bone Morphogenetic Protein) |
| PMC10558021__F2 | Cyclophosphamide metabolic pathway |
| PMC10558228__F1 | NFKB signaling pathway and targets of inhibitors against neuroinflammation in AD |
| PMC10558228__F3 | NLRP3 signaling pathway and targets of inhibitors against neuroinflammation in AD |
| PMC10558228__F4 | PPAR, STAT3 and PI3K/Akt signaling pathways and targets of inhibitors against neuroinflammation in AD |
| PMC10558228__F5 | Targeting inflammatory signaling pathways with drugs shows promise in AD treatment |
| PMC10558709__F7 | The main findings on HMEC-1 |
| PMC10559578__F2 | Production of IL-1B and its transduction signaling pathway |
| PMC10559873__F6 | Detail of pathways |
| PMC10559929__F5 | Explain the correlation among the chemical components, candidate targets, involved pathways and corresponding pharmacological effects of AGNHW |
| PMC10559930__F1 | Mechanism involved in ZNF703 including the signaling pathway, upstream regulation network and downstream targets |
| PMC10559995__F1 | Signaling Pathway of Estrogen Receptor |
| PMC10559995__F3 | Estrogen metabolism pathway in humans |
| PMC10560454__F1 | tFNAs improve hUMSC chondrogenic potential through the regulation of the PI3K/AKT pathway |
| PMC10561274__F2 | Inflammation associated signaling activated by fractalkine |
| PMC10561294__F7 | Construction of PPI networks |
| PMC10562563__F1 | Toll-Like Receptors (TLRs) signaling pathways, intra-, and inter-signaling crosstalk circuits, and their regulatory loops |
| PMC10564417__F7 | Schematic diagram showing the proposed mechanisms by which exosomal miR-486-5p derived from M2 macrophages regulates the osteogenic and adipogenic differentiation of BMMSCs |
| PMC10564423__F8 | Schematic diagram illustrated how core fucosylation regulated alveolar epithelial cells senescence in pulmonary fibrosis through TGFB/Smad2/3 pathway in vivo and in vitro |
| PMC10564428__F8 | Myeloid-specific knockout of SHP2 regulates PI3K/PLCG signaling pathway to protect against early myocardial infarction injury |
| PMC10565042__F1 | Diverse types and molecular mechanisms of the Wnt signaling pathway |
| PMC10565042__F2 | Involvement of ncRNAs in modulating the Wnt signaling pathway in prostate cancer |
| PMC10565042__F3 | Wnt signaling pathway-related ncRNAs in the regulation of invasion and migration in prostate cancer |
| PMC10565042__F4 | Wnt signaling pathway-related ncRNAs in the regulation of EMT, apoptosis, stemness, and CRPC formation in prostate cancer |
| PMC10565453__F2 | Organelle-level mechanisms of mitochondrial quality control |
| PMC10565453__F3 | Altered mitochondrial quality control in renal tubule cells under high glucose conditions |
| PMC10568034__F2 | Manner in which the studied product acts on the Wnt pathway in lung cancer |
| PMC10568316__F1 | Multifunctional role and mechanism of IMφs in NEC pathogenesis |
| PMC10568316__F2 | Mφ-related inflammatory signaling pathways in NEC |
| PMC10570508__F2 | PITX1 acts as a core gene that regulates the p53 signaling pathway |
| PMC10570830__F2 | PIFs are the key regulators of skotomorphogenesis |
| PMC10571545__F5 | TF–FVIIa–driven PAR2 activation triggers EV generation from human TNBC cells, which promotes EMT in non–metastatic breast cancer cells, leading to the induction of proliferation, migration, invasion, and anti–apoptosis |
| PMC10571577__F1 | HGF/c-MET signaling pathway |
| PMC10571577__F3 | Acquired mechanisms of resistance to MET-Is |
| PMC10571651__F1 | Normal physiologic MET receptors form dimers upon HGF signaling, and Cbl binding leads to ubiquitination |
| PMC10571700__F5 | Gene expression (CAMs) |
| PMC10571713__F1 | Lipid sources include the de novo fatty acid synthesis pathway and exogenous lipid uptake |
| PMC10571764__F1 | Therapeutic mechanisms involving elotuzumab and Anti-SLAMF3 in multiple myeloma (MM) |
| PMC10571814__F8 | Oxytocin signalling pathway, with yellow boxes representing proteins identified in this study and green circles representing metabolites identified in this study |
| PMC10571979__F8 | Norrin signals through DVL1 to stimulate barrier properties |
| PMC10572085__F2 | Signaling pathways of the CD44 intracellular domain (CD44-ICD) under hypoxia |
| PMC10572085__F3 | Signaling pathway activated by HA-CD44 interaction |
| PMC10572085__F5 | HA-CD44 binding-activated signaling pathways |
| PMC10572156__F7 | Beta-Sitosterol Suppresses Lipopolysaccharide-Induced Inflammation and Lipogenesis Disorder in Bovine Mammary Epithelial Cells |
| PMC10572209__F7 | Molecular pathways in Hep3B cell line |
| PMC10572466__F6 | Schematic drawing illustrating the action mechanisms underlying the effects of baicalin on cytoskeleton rearrangement induced by PVL in BMECs |
| PMC10572524__F7 | DEGs in NOD/Toll-like receptor signaling pathway |
| PMC10572622__F3 | Representation of part of phenylpropanoids and oleuropein biosynthetic pathway in olive fruits |
| PMC10572663__F2 | Signaling pathways regulating EMT |
| PMC10572663__F3 | Hypothetical contribution of EMT-like process to the pathophysiology of RA |
| PMC10572663__F4 | Hypothetical contribution of EMT to the pathophysiology of pSS |
| PMC10572708__F12 | Lipid and atherosclerosis metabolic pathway |
| PMC10572711__F2 | Major and other possible molecular pathways associated with NLRs in IBD |
| PMC10572723__F3 | Interacting compounds and PTMs of PPARG that regulate its function in the endothelium |
| PMC10573125__F1 | The JAK-STAT signaling pathway by LNK in hormone receptor-positive breast cancer and non-tumor cells |
| PMC10573127__F1 | Airway epithelial differentiation pathways |
| PMC10573127__F2 | Molecular pathways involved in multiciliogenesis |
| PMC10573127__F3 | Secretory cell (SC) differentiation programs |
| PMC10573510__F6 | Asthma pathway |
| PMC10573607__F4 | Soluble sugar, cellulose, and lignin contents |
| PMC10573612__F2 | Exploring the Cellular and Molecular Mechanism of Discoidin Domain Receptors (DDR1 and DDR2) in Bone Formation, Regeneration, and Its Associated Disease Conditions |
| PMC10573925__F1 | Effect of sclerostin on the Wnt/Beta-catenin pathway |
| PMC10578286__F1 | Insulin signaling pathway schematic |
| PMC10583183__F11 | Mechanism that HRF prompts pyroptosis via CaSR/NLRP3/caspase1 signaling pathway under MI/R conditions |
| PMC10584331__F1 | Ferroptosis mechanisms |
| PMC10584331__F2 | Reverse of liver fibrosis by inducing ferroptosis by bioactivated compounds in HSCs |
| PMC10586346__F3 | Osteogenic differentiation-related signal pathway diagram |
| PMC10586807__SF3_1. | Correlation between CRISPR KO and CRISPRa screen gene hits within certain pathways |
| PMC10590753__F11 | Differentially expressed proteins and metabolites KEGG annotation and visual analysis in the purine metabolism pathway |
| PMC10594068__F3 | Bone is a tissue that consists of diverse cell types (osteoblasts, osteoclasts) that interact in a complex manner |
| PMC10603888__F10 | Signal path analysis: (A) thyroid hormone synthesis (Calcium ions within the cell are transported outside the cell via the transmembrane, as indicated by the red boxes |
| PMC10603966__F5 | Schematic view showing melatonin-mediated actions in stroke |
| PMC10603981__F1 | Signaling pathways involved in ferroptosis |
| PMC10603981__F2 | Necroptosis signaling pathways |
| PMC10604135__F6 | Mutated proteins in four patients colored with red, green, cyan, and brown with arrangements of their roles on Wnt and mTOR signaling pathways |
| PMC10604364__F3 | Illustration depicting the formation and fate of hybrid cells |
| PMC10604560__F3 | Lipid metabolism |
| PMC10604902__F1 | Oxidative stress from dysregulated NOX activation and mitochondrial dysfunction regulates the signaling pathways involved in initiating and maintaining AF |
| PMC10604974__F2 | Autophagy in viral infection |
| PMC10604974__F3 | Activation mechanism of the NLRP3 inflammasome |
| PMC10604999__F1 | Scheme illustrating the main hippocampal mechanisms observed in the diabetes-related depression |
| PMC10605176__F1 | Neuroprotection by the volatile anesthetics sevoflurane and isoflurane |
| PMC10605176__F3 | Noble gas-induced neuroprotection |
| PMC10605254__F4 | PDLIMs and integrin signaling pathway |
| PMC10605254__F5 | PDLIMs and TGFB signaling pathway |
| PMC10605254__F6 | PDLIMs and MAPK and NFKB signaling pathway |
| PMC10605306__F1 | Interleukin-33 signaling pathway |
| PMC10605590__F7 | The potential non-genomic P4 action in colorectal cancer |
| PMC10605613__F3 | Cellular regulatory pathways involving PrPC protein in cancer |
| PMC10605634__F1 | Tumor intrinsic factors related to immune evasion and ICI resistance |
| PMC10606123__F1 | Underlying mechanism of histone deacetylases in regulating ovarian cancer metastasis |
| PMC10607207__F1 | Neuroprotective intracellular signaling pathways in the central nervous system involving TRPC6 activation |
| PMC10607277__F9 | Compound–disease–therapeutic targets-core pathways network; red triangles represent diseases, blue triangles represent compounds, purple ovals represent pathways, and green ovals represent targets |
| PMC10607347__F3 | The anti-apoptotic action of MSCs in the hepatocyte–MSC co-cultures |
| PMC10607693__F5 | Fatty acid biosynthesis and TAG assembly pathway reconstruction |
| PMC10607711__F2 | Propagation of pressure in the epidermis and certain mechanotransducers involving the modulation of mechanical stimuli in keratinocytes |
| PMC10608450__F5 | Protein–protein interactions between 341 members of antimicrobial peptides in Trachinotus ovatus |
| PMC10608541__F13 | Pathways and localization of astaxanthin biosynthesis and esterification in Haematococcus algae |
| PMC10608708__F7 | Mapping of the top targets in the PI3K-AKT signaling pathway |
| PMC10609794__F2 | The PRG4-CD44 axis in mitigating the pro-inflammatory and pro-fibrotic signaling pathways in DJDs |
| PMC10609905__F1 | Vitamin D synthesis pathway |
| PMC10609929__F2 | Modeled DDIs for phenytoin |
| PMC10610064__F1 | ABL Kinase Activation and Signaling in Solid Tumors |
| PMC10610100__F2 | Protein–protein interaction (PPI) network map of the KEGG enriched signal pathway of differential genes |
| PMC10610144__F7 | SBP effects on BMP2-Smad1/5/9-Runx2 signaling pathway |
| PMC10610204__F4 | Activation of DNA damage-induced checkpoint signaling pathway in ATM-deficient cells and mechanism of ATR inhibitor and ATM defect-induced synthesis and lethality (by Figdraw) |
| PMC10610204__F5 | WEE1 and TP53 synthetic lethal interaction mechanism (by Figdraw) |
| PMC10610230__F7 | Mechanism underlying the therapeutic effect of PT on IDD |
| PMC10610499__F2 | TLR4 downstream signaling pathways |
| PMC10610499__F3 | Liver manages a complex antigenic load from the blood, relying on immune tolerance mechanisms and mainly LPS tolerance |
| PMC10610499__F5 | Interplay between EVs and the TLR4 signaling pathway in the context of HCC |
| PMC10610897__F7 | Interaction network of genes and co-expressed lncRNAs involved in IAV replication regulation in MDCK cells |
| PMC10616926__F1 | Schematic drawing of the major neuroprotective signaling pathways regulated by ghrelin and GHS |
| PMC10618387__F3 | Apoptosis is mediated by intrinsic and extrinsic pathways |
| PMC10618387__F5 | Crosstalk between the signaling pathway of pyroptosis, apoptosis, and autophagy |
| PMC10619560__F4 | Biosynthetic pathway of caproic acid and other organic acids in C. butyricum GD1-1 |
| PMC10620037__F3 | IL-37 inhibits liver fibrosis |
| PMC10620037__F4 | IL-37 inhibits hepatocellular carcinoma (HCC) |
| PMC10620831__F8 | PRMTs regulate antiviral innate immunity |
| PMC10622988__F4 | Tumor-associated signaling pathways influenced by lncRNA SOX21-AS1 in breast cancer, lung adenocarcinoma, and glioma |
| PMC10622993__F2 | Common signaling pathways and ALDH1 expression in CCA |
| PMC10623083__F7 | CFH knockdown suppresses the stemness of breast cancer cells through regulation of the EPB41L3/MAPK axis |
| PMC10623085__F7 | Proposed signaling pathway by which NE mediates HepG2 cell proliferation |
| PMC10625490__F2 | HIV infection induces intestinal mucosal barrier damage and immune cell dysfunction, which aggravates the inflammatory response |
| PMC10627266__F5 | CEBPB increases inflammation/SASP independent of DDR pathway to promote senescence |
| PMC10631767__F1 | Interactions between CAFs and CCA cells |
| PMC10631767__F2 | Associations between CCA, TAMs and TANs |
| PMC10635689__F8 | BJ-5ta Exo exert a protective effect against UVB-induced photoaging |
| PMC10635949__F5 | Effect of BD exposure during adolescence on skeletal muscle metabolism and myokine secretion |
| PMC10636769__F2 | IORT regulates the proliferation of microRNA-223, thereby reducing EGF levels and ultimately attenuating the EGFR signaling pathway |
| PMC10644365__F2 | Signaling pathways associated with ERA |
| PMC10647353__F2 | Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and Prognosis |
| PMC10647353__F4 | Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and Prognosis |
| PMC10647353__F6 | Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and Prognosis |
| PMC10647460__F7 | Regulatory mechanism of cis-9, trans-11 CLA on milk fat synthesis |
| PMC10647618__F1 | Canonical Hedgehog Signaling Pathway |
| PMC10647767__F1 | Developments in Genetics: Better Management of Ovarian Cancer Patients |
| PMC10647767__F4 | Developments in Genetics: Better Management of Ovarian Cancer Patients |
| PMC10647767__F5 | Developments in Genetics: Better Management of Ovarian Cancer Patients |
| PMC10647767__F6 | Developments in Genetics: Better Management of Ovarian Cancer Patients |
| PMC10647767__F8 | Developments in Genetics: Better Management of Ovarian Cancer Patients |
| PMC10648005__F1 | Main molecular consequences of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway activation |
| PMC10648128__F5 | DEGs belonging to the gap junction signaling pathway in the hippocampus (magenta) and frontal cortex (red) of OXYS rats at PND3 and PND10 |
| PMC10648403__F6 | Expression profiles of genes involved in the phenylpropanoid biosynthesis pathway |
| PMC10648512__F3 | Effect of exosomes derived from glioma stem cells and containing miR-26a on the BBB |
| PMC10648520__F8 | Brief Review of Bone Cell Function and Importance |
| PMC10648679__F1 | PSCs have emerged as a promising candidate for stem cells in PDAC |
| PMC1064894__F3 | Toll-like receptor (TLR) signaling pathways |
| PMC10648981__F3 | Jasmonates in coordinating secondary with primary metabolism |
| PMC10649278__F6 | Diagram of IL-17 signaling pathway |
| PMC10649670__F6 | Central illustration |
| PMC10650070__F2 | NFKB, MAPK and Oct-1 pathways for expression of Beta-defensins |
| PMC10650444__F8 | Compound 6b for promoting apoptosis of HepG2 cells |
| PMC1065305__F1 | Components of the AhR-mediated lacZ reporter assay |
| PMC10657592__F1 | Connective tissue growth factor: Role in trabecular meshwork remodeling and intraocular pressure lowering |
| PMC10665998__F6 | Long non‑coding RNA PEG13 regulates endothelial cell senescence through the microRNA‑195/IRS1 axis |
| PMC10669090__F2 | The influence of risk factors on the formation of peak bone mass |
| PMC10669195__F1 | Unleashing the Potential of Nrf2: A Novel Therapeutic Target for Pulmonary Vascular Remodeling |
| PMC10669226__F3 | Cardiac Hypertrophy Signaling pathway is predicted to be upregulated in EVPs from aged animals |
| PMC10669226__F4 | Production of Nitric Oxide and Reactive Oxygen Species in Macrophages signaling pathways is predicted to be upregulated in EVPs from aged animals |
| PMC10669348__F3 | Schematic and simplified overview of the intracellular transduction cascades induced by 5-HT2AR TrkB and Sig-1R receptor activation by psychedelics |
| PMC10669501__F2 | Interplay of NRF2 in Kupffer cells and HSCs during the progression of chronic liver disease |
| PMC10669528__F4 | Process of GSDMD in the pathogenesis of systemic onfection |
| PMC10669584__F1 | APE1/Ref-1 role in inflammatory bowel disease and the potential of redox signaling inhibition |
| PMC10669635__F2 | PI3K-Akt signalling pathway |
| PMC10669635__F3 | Partial epithelial to mesenchymal transition (p-EMT) and full EMT with associated biological markers |
| PMC10669822__F6 | “PPAR signaling pathway” was an upregulated KEGG pathway for the transcriptomics profiling of HMEC-1 treated with MPE (0 |
| PMC10670053__F1 | Most common signalling pathways active in muscle and adipocytes during cancer-associated cachexia |
| PMC10670187__F1 | LncRNA MIR4435-2HG is involved in signaling pathways for cancer progression |
| PMC10670368__F2 | SHP2 is critical in regulating RAS/ERK, PI3K/Akt, and JAK/STAT signaling pathways in cancer cells |
| PMC10670380__F3 | Multi-level functional integration of extended regions of the human genome, above and beyond individual noncoding RNAs |
| PMC10670414__F8 | Anticancer Effects of 6-Gingerol through Downregulating Iron Transport and PD-L1 Expression in Non-Small Cell Lung Cancer Cells |
| PMC10670481__F6 | Analysis of KEGG pathway and interactive enrichment networks |
| PMC10671144__F1 | Carboplatin molecular network in cancer |
| PMC10671144__F3 | Upstream regulator analysis of cisplatin revealed the upregulation in FAS, PRKCA, and CDKN1A, and involvement of tumor microenvironment pathway (lung adenocarcinoma (LUAD) [lung] cisplatin 9800) |
| PMC10671144__F7 | Network analysis of oxaliplatin revealed that oxaliplatin as a master regulator was predicted to be inhibited and the SPINK1 pancreatic cancer pathway was inactivated in ischemic cardiomyopathy |
| PMC10671169__F7 | NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1B Signaling Pathway |
| PMC10671302__F4 | Roles and Future Perspectives of Chitinase 3-like 1 in Macrophage Polarization and the Development of Diseases |
| PMC10671441__F2 | Wnt Signaling pathway |
| PMC10671441__F4 | IPA Core analysis of the Epithelial Adherens Junctions Signaling in SW480 AHCY deficient cells with increased expression of LEF1 protein |
| PMC10671441__F8 | S-Adenosylhomocysteine Hydrolase Downregulation on Wnt Signaling Pathway in SW480 Cells |
| PMC10671441__F9 | Human Embryonic Stem Cell Pluripotency Signaling |
| PMC10671474__F1 | Current endocrine and targeted treatment of metastatic ER+ breast cancer |
| PMC10671474__F2 | Common mechanisms of secondary endocrine resistance in advanced ER+ breast cancer |
| PMC10671516__F1 | Paracrine-mediated signaling between granulosa cells and oocytes |
| PMC10671516__F3 | Granulosa cell glucose and lipid metabolism on oocytes |
| PMC10671577__F3 | MAPK signaling pathway containing T |
| PMC10672284__F1 | Multifaceted functions of (AMPs): (A) Depiction of the signaling pathway involved in Gram-negative bacteria-induced infection caused by lipopolysaccharides (LPS) |
| PMC10672452__F1 | LPS-induced inflammatory response of the innate immune system and the anti-inflammatory effect of LPS-binding peptides/proteins from marine invertebrates |
| PMC10672974__F13 | Recent Advances in Drug Discovery for Triple-Negative Breast Cancer Treatment |
| PMC10673274__F1 | Sites of cellular PPi formation and details of galactose metabolism |
| PMC10674583__F1 | Nrf2-keap1/ARE signaling pathway |
| PMC10674663__F7 | Comparative Analysis of Cd Uptake and Tolerance in Two Mangrove Species (Avicennia marina and Rhizophora stylosa) with Distinct Apoplast Barriers |
| PMC10674800__F6 | Transcriptomics and Physiological Analyses Reveal Changes in Paclitaxel Production and Physiological Properties in Taxus cuspidata Suspension Cells in Response to Elicitors |
| PMC10675221__F2 | Results of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis |
| PMC10675221__F3 | Direct targets of the ethyl acetate extract from decoction of Sargentodoxa cuneata (EAdSc) action on the NOD-like receptor signaling pathway |
| PMC10675562__F6 | HS potential inhibitory mechanism of GA via TGFB/Smad signaling pathway |
| PMC10685161__F1 | Major UPR pathways initiated from the ER and the potential role of AGR2 in interacting with EGFR and MUC2 |
| PMC10685161__F2 | Role of AGR2 as a critical regulator of maintaining intestinal barrier function by affecting the intestinal goblet cell differentiation, maturation, and secretion of MUC2 |
| PMC10685161__F3 | Effect of UPR-AGR2 signaling pathways on goblet cells during ETEC infection |
| PMC10686715__F2 | Exosomes from different MSCs mediate PCD in myocardial cells after myocardial infarction |
| PMC10686715__F4 | Angiogenic effect of exosomes released by different MSCs after MI |
| PMC10686715__F5 | Exosomes secreted by different sources of MSCs regulate the inflammatory microenvironment after myocardial infarction |
| PMC10686798__F1 | Wnt/Bcatenin signaling pathway |
| PMC10688450__F4 | Link between U2AF1 and NFKB signalling in MDS and AML |
| PMC10688769__F2 | Cell-produced SASP affects OA |
| PMC10688769__F4 | miRNA alterations affect cartilage synthesis |
| PMC1069556__F6 | Effect of NS5A on the Beta-catenin signaling pathway |
| PMC1069621__F5 | Two models for coupling of circadian and cell cycles |
| PMC107042__F1 | Diagram showing the relationships among the regulatory factors governing srf transcription initiation |
| PMC10704547__F1 | AhR ligand-activated pathways mediate anticancer activities in breast cancer cells |
| PMC10704547__F2 | AhR ligand-activated pathways mediate pro-cancer activities in breast cancer cells |
| PMC10704547__F4 | AhR ligand-activated pathways/genes exhibit anticancer or pro-cancer activity in breast cancer cells |
| PMC10705282__F2 | Exogenous pathway is a process for delivering triglycerides to peripheral tissues using chylomicrons and VLDLs |
| PMC10705282__F4 | In PTC, glycolysis is crucial for tumor growth |
| PMC10705325__F13 | Study on the Effect of Oleic Acid-Induced Lipogenic Differentiation of Skeletal Muscle Satellite Cells in Yanbian Cattle and Related Mechanisms |
| PMC10705747__F6 | CBD’s neuroprotective mechanism in ABeta-induced impairments |
| PMC10705753__F1 | Illustration of semaphorin 6A–D signaling pathways and their interaction with the cellular molecular network in cancer cells |
| PMC10705753__F3 | Illustration of the mTOR–Sema6D–PPARG signaling pathway in controlling macrophage polarization toward anti-inflammatory (antitumorigenic) phenotype M2 via regulation of fatty acid uptake and metabolic reprogramming |
| PMC10705939__F2 | Schematic diagram of the regulatory pathways of K+ channels or transporters in Arabidopsis and rice |
| PMC10706216__F16 | Activation of UPR signaling pathways during ER-stress, caused by TAA injections, in liver cells |
| PMC10706414__F1 | Interleukin (IL)-37 maintains its anti-inflammatory outcomes by limiting IL-18RA from adhering to IL-18 and by attracting the orphan decoy IL-1R8 to the IL-18R/IL-37/IL-1R8 complex |
| PMC10706418__F5 | Analysis of hormone signaling transduction in response to CGMMV infection |
| PMC10706592__F1 | TRAIL signaling pathway |
| PMC10706592__F3 | TRAIL signaling pathway indicating the therapeutic targets modulated by flavonoid compounds |
| PMC10706690__F6 | CPNE7 study schema related to EMT |
| PMC10706706__F6 | DEGs expression pattern diagram of JA biosynthetic pathway in mustard leaves after beet armyworm larvae chewing |
| PMC10706788__F10 | Pathway of purine metabolism by EHP in the early stages of infection |
| PMC10706788__F11 | Pathway of glutathione metabolism by EHP in the early stages of infection |
| PMC10706788__F13 | Pathway of glutathione metabolism by EHP in the late stages of infection |
| PMC10706934__F1 | Hypothetic signalling pathway triggered by FK506 |
| PMC10707303__F5 | Fibrotic factors in the development of DKD |
| PMC10707854__F2 | Mechanism and Progress of Natural Products in the Treatment of NAFLD-Related Fibrosis |
| PMC10707854__F3 | Mechanism and Progress of Natural Products in the Treatment of NAFLD-Related Fibrosis |
| PMC10708062__F10 | Analysis of DEGs involved in citrate cycle pathway in roots under osmotic stress |
| PMC10708062__F8 | Analysis of DEGs involved in carbon fixation under osmotic stress |
| PMC10708146__F2 | GSDMD-mediated pyroptosis in DCM |
| PMC10722483__F6 | Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse |
| PMC10723408__F1 | Workflow and methodology used in this work |
| PMC10723546__F3 | Biological pathways in ccRCC |
| PMC10725447__F0 | Upregulation of FAM83F by c-Myc promotes cervical cancer growth and aerobic glycolysis via Wnt/Beta-catenin signaling activation |
| PMC10728021__F5 | Proposed combination treatment strategy to tackle p53‐mutant esophageal squamous cell carcinoma (ESCC) tumors with a WEE1 inhibitor |
| PMC10728906__F4 | Inflammatory activation of astrocytes and microglia by Alpha-Syn and phenotypic switching between astrocytes and microglia |
| PMC10728939__F3 | Signaling pathways regulated by BAMBI |
| PMC10731584__F7 | Simplified de novo sphingolipid biosynthesis pathway |
| PMC10733979__F1 | Key cellular metabolic pathways in which NAD(P)H and FAD are involved, including glycolysis, the TCA cycle, oxidative phosphorylation, fatty acid oxidation and synthesis, and the glutathione pathway |
| PMC10739988__F2 | Advance of the third‑generation EGFR‑TKI in the treatment of non‑small cell lung cancer (Review) |
| PMC10740436__F3 | Comparative Serum Proteome Profiling of Canine Benign Prostatic Hyperplasia before and after Castration |
| PMC10740485__F7 | The proposed mechanism of Nrf2 in osteoporosis |
| PMC10740511__F4 | Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer |
| PMC10740511__F5 | Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer |
| PMC10740567__F1 | Signaling pathways involved in the inhibition of apoptosis by Apicomplexan protozoa |
| PMC10740672__F10 | Oncogenic signaling pathway plays a crucial role in tumor suppression in vivo |
| PMC10740672__F8 | Growth suppression mediated by p53 |
| PMC10740823__F9 | Graphical abstract of the mechanism |
| PMC10740873__F2 | Ihh signaling pathway in regulating osteoblast differentiation (refer to Pan et al |
| PMC10740933__F3 | (Left) Initial biosynthetic pathway for the formation of a lipofuscin fluorophore A2E in photoreceptor outer segment (OS) and its structure as a component of lipofuscin (LF) in the RPE cell |
| PMC10741038__F5 | PC biosynthesis in S |
| PMC10741130__F6 | Oleocanthal, an Antioxidant Phenolic Compound in Extra Virgin Olive Oil (EVOO): A Comprehensive Systematic Review of Its Potential in Inflammation and Cancer |
| PMC10741569__F1 | Viruses modulate the EGFR signaling network |
| PMC10741648__F1 | Reelin signaling pathway |
| PMC10741662__F1 | WNT/Beta-catenin signaling pathway |
| PMC10741690__F2 | Mitophagy pathway |
| PMC10741879__F7 | Schematic model showing the tumor-progression-promoting interaction between CRC cells and TAMs |
| PMC10741975__F5 | Compound-pathway network has 41 points and 151 lines |
| PMC10741975__F7 | Chemokine signaling pathway and PI3K-Akt signaling pathway influenced by esaxerenone |
| PMC10742113__F1 | Comparative signaling pathways mediated by adiponectin, leptin and resistin |
| PMC10742113__F2 | Comparative signaling pathways of IL-6, PAI-1 and MCP-1 |
| PMC10742113__F3 | Signaling pathway mediated by Escherichia coli lipopolysaccharides (LPSs) |
| PMC10742113__F5 | Bacterial degradation of trimethylamine (TMA) for trimethylamine N-oxide (TMAO) formation |
| PMC10742271__F4 | Signaling pathway involved in the osteogenesis process due to Mg effect |
| PMC10742340__F1 | Molecular signaling pathways associated with Mn neurotoxicity |
| PMC10742434__F1 | Gut microbiota–host interplays in tryptophan and tyrosine metabolism, which affect mood and emotional states |
| PMC10742465__F7 | The proposed cardioprotective mechanism of hydrogen after CIH exposure |
| PMC10742473__F4 | Canonical and alternative signaling pathways in B-cells |
| PMC10743075__F10 | n-3-PUFA administration decreased mRNA expression of pro-inflammatory cytokines, as documented in the TNF signaling pathway |
| PMC10743075__F9 | N-3-PUFAs decreased mRNA expression of key enzymes of fatty acid biosynthetic pathway |
| PMC10743093__F3 | Schematic illustration highlighting targets of senotherapeutics including senolytics and senomorphics |
| PMC10743408__F3 | Mechanistic illustration of downregulation of interferon-responsive genes and JAK/STAT1/2 signaling pathway |
| PMC10743522__F3 | The signaling pathways regulated by phase separation during development |
| PMC10743556__F2 | Keap1/Nrf2/ARE signaling pathway |
| PMC10743592__F2 | Presentation of the action of ghrelin on autophagy |
| PMC10743592__F3 | Presentation of association between apoptosis and necroptosis |
| PMC10743660__F1 | Key molecular events of EMT |
| PMC10743660__F3 | Nexus of Inflammation-Induced Epithelial-Mesenchymal Transition and Lung Cancer Progression: A Roadmap to Pentacyclic Triterpenoid-Based Therapies |
| PMC10743660__F4 | Immune component of inflammation-induced EMT in lung cancer |
| PMC10743660__F6 | Inhibition of inflammation-induced EMT by PTs |
| PMC10743660__F7 | Inhibition of stemness by PTs |
| PMC10743675__F3 | Osteobiologies for Spinal Fusion from Biological Mechanisms to Clinical Applications: A Narrative Review |
| PMC10743675__F4 | Bone morphogenetic proteins (BMPs) signaling pathways |
| PMC10743706__F2 | Biosynthetic pathways of BR |
| PMC10744232__F3 | Pomegranate (Punica granatum L.) and Its Rich Ellagitannins as Potential Inhibitors in Ulcerative Colitis |
| PMC10744266__F1 | Action of warfarin relevant to pharmacogene identification (further details provided in the Data Supplement) |
| PMC10744281__F1 | Interconnection of glycolysis with other metabolic pathways |
| PMC10744281__F3 | Apoptotic process by glycolysis and lipid metabolism in glioma |
| PMC10744281__F4 | Autophagy by glycolysis, lipid metabolism, and glutamine in glioma |
| PMC10744776__F4 | Anticancer properties of glycyrrhizinic acid in cervical cancer models |
| PMC10744863__F1 | Pathophysiology of acquired aplastic anemia (AA) |
| PMC10745077__F6 | Pro-apoptotic Bax-induced release of cytochrome stimulates the caspase signaling pathway in the mitochondria, resulting in enhanced hepatic cell apoptosis |
| PMC10745105__F6 | Working model of GAH-dependent vascular repair |
| PMC10745682__F2 | Potential association between the ER stress signaling pathway and obesity |
| PMC10745821__F9 | Proposed model of the signaling pathway induced by the CSHE treatment |
| PMC10746942__F1 | SAMMSON via different mechanisms exerts its oncogenic roles in melanoma |
| PMC10746942__F2 | The function of SAMMSON in different cancers |
| PMC10747773__F4 | HCV-induced ROS/JNK/Itch signaling pathway promotes VSP4A polyubiquitylation, leading to enhancement of VPS4A ATPase activity, thereby upregulating the release of HCV particles |
| PMC10748092__F2 | Colorectal Cancer Stem Cells and Targeted Agents |
| PMC10748259__F6 | Molecular mechanisms leading to the detection of viral genome |
| PMC10748259__F7 | Involvement of metabolism in viral genome detection |
| PMC10748259__F8 | Antiviral effectors and cell metabolism interactions |
| PMC10748332__F5 | Signaling pathways involved in neuroprotective mechanisms |
| PMC10749620__F2 | NRF2 peptide with its seven Neh domains and their roles |
| PMC10749620__F3 | KEAP1-NRF2-ARE pathway |
| PMC10749620__F4 | KEAP1-NRF2 by P62 non-canonical pathway |
| PMC10750202__F2 | Regulatory mechanisms of circular RNAs during human mesenchymal stem cell osteogenic differentiation |
| PMC10750205__F2 | Endosialin in Cancer: Expression Patterns, Mechanistic Insights, and Therapeutic Approaches |
| PMC10750275__F1 | YAP Signaling in Regulation of Programmed Cell Death and Drug Resistance in Cancer |
| PMC10750275__F7 | YAP Signaling in Regulation of Programmed Cell Death and Drug Resistance in Cancer |
| PMC10750282__F2 | CGAS-STING Signalling in Metabolic Diseases: from Signalling Networks to Targeted Intervention |
| PMC10750282__F3 | CGAS-STING Signalling in Metabolic Diseases: from Signalling Networks to Targeted Intervention |
| PMC10750283__F4 | Nuclear Receptors in the Pathogenesis and Treatment of Non-alcoholic Fatty Liver Disease |
| PMC10750287__F4 | Cross-Communication of Cuproptosis and Regulated Cell Death in Human Pathophysiology |
| PMC10750287__F6 | Molecular mechanisms of autophagy triggered by excess Cu |
| PMC10750291__F4 | Biological mechanism and emerging therapeutic interventions of liver aging |
| PMC10750291__F5 | Biological mechanism and emerging therapeutic interventions of liver aging |
| PMC10750291__F6 | Biological mechanism and emerging therapeutic interventions of liver aging |
| PMC10750294__F8 | MANF Promotes Unexplained Recurrent Miscarriages by Interacting with NPM1 and Downregulating Trophoblast Cell Migration and Invasion |
| PMC10751671__F1 | Impact of Physical Exercise on Melanoma Hallmarks: Current Status of Preclinical and Clinical Research |
| PMC10751671__F2 | Impact of Physical Exercise on Melanoma Hallmarks: Current Status of Preclinical and Clinical Research |
| PMC10751868__F5 | H19: An Oncogenic Long Non-coding RNA in Colorectal Cancer |
| PMC10751872__F3 | Advances in Regulating Cellular Behavior Using Micropatterns |
| PMC10751873__F2 | High expression level of CRNDE contributes to CRC by upregulating the signaling pathways such as Ras/MAPK, Wnt/Beta-catenin |
| PMC10751873__F4 | CRNDE: A Pivotal Oncogenic Long Non-Coding RNA in Cancers |
| PMC10751873__F5 | CRNDE: A Pivotal Oncogenic Long Non-Coding RNA in Cancers |
| PMC10754983__F7 | Current insight on the mechanisms of programmed cell death in sepsis-induced myocardial dysfunction |
| PMC10755185__F6 | Transcriptome Changes and Metabolic Outcomes After Bariatric Surgery in Adults With Obesity and Type 2 Diabetes |
| PMC10755271__F6 | Network pharmacology and experimental evidence: MAPK signaling pathway is involved in the anti-asthma roles of Perilla frutescens leaf |
| PMC10755469__F2 | Crosstalk between neutrophil extracellular traps and immune regulation: insights into pathobiology and therapeutic implications of transfusion-related acute lung injury |
| PMC10755684__F2 | Neuroinflammation in the transition of acute to chronic pain and the opioid-induced hyperalgesia and tolerance |
| PMC10755915__F6 | Soluble CD83 modulates human-monocyte-derived macrophages toward alternative phenotype, function, and metabolism |
| PMC10756743__F5 | Transcription Analysis of the THBS2 Gene through Regulation by Potential Noncoding Diagnostic Biomarkers and Oncogenes of Gastric Cancer in the ECM-Receptor Interaction Signaling Pathway: Integrated System Biology and Experimental Investigation |
| PMC10756743__F6 | Transcription Analysis of the THBS2 Gene through Regulation by Potential Noncoding Diagnostic Biomarkers and Oncogenes of Gastric Cancer in the ECM-Receptor Interaction Signaling Pathway: Integrated System Biology and Experimental Investigation |
| PMC10757071__F5 | Significance of long non-coding RNAs in the pathogenesis, diagnosis and treatment of inflammatory bowel disease |
| PMC10757365__F3 | Immune checkpoints in antitumor response: a potential antitumor immunotherapy |
| PMC10757641__F1 | G protein-coupled receptors and obesity |
| PMC10757967__F1 | Advances in the regulatory mechanisms of mTOR in necroptosis |
| PMC10757967__F2 | Advances in the regulatory mechanisms of mTOR in necroptosis |
| PMC10757967__F3 | Advances in the regulatory mechanisms of mTOR in necroptosis |
| PMC10758056__F8 | NRF2 promotes radiation resistance by cooperating with TOPBP1 to activate the ATR-CHK1 signaling pathway |
| PMC10758146__F1 | Lithium exerts neuroprotective effects in ischemic stroke through multiple mechanisms |
| PMC10758155__F6 | Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis |
| PMC10758279__F2 | In Vitro and In Vivo Analysis of Neurotrophin-3 Activation of Arf6 and Rac-1 |
| PMC10758458__F1 | Advances in the role of microRNAs associated with the PI3K/AKT signaling pathway in lung cancer |
| PMC10758458__F2 | Advances in the role of microRNAs associated with the PI3K/AKT signaling pathway in lung cancer |
| PMC10758458__F3 | Advances in the role of microRNAs associated with the PI3K/AKT signaling pathway in lung cancer |
| PMC10758489__F1 | Metabolic reprogramming in the tumor microenvironment: unleashing T cell stemness for enhanced cancer immunotherapy |
| PMC10758544__F9 | Byakangelicol suppresses TiPs-stimulated osteoclastogenesis and bone destruction via COX-2/NFKB signaling pathway |
| PMC10758606__F1 | NFKB signaling system in the generation of B-cell subsets: from germinal center B cells to memory B cells and plasma cells |
| PMC10758851__F1 | Development and Clinical Applications of PI3K/AKT/mTOR Pathway Inhibitors as a Therapeutic Option for Leukemias |
| PMC10758887__F16 | Current biomarkers and treatment strategies in Alzheimer disease: An overview and future perspectives |
| PMC10758965__F2 | Regulatory mechanisms of one-carbon metabolism enzymes |
| PMC10758965__F3 | Regulatory mechanisms of one-carbon metabolism enzymes |
| PMC10758965__F5 | Regulatory mechanisms of one-carbon metabolism enzymes |
| PMC10759256__F1 | DMMIC derivatization-assisted liquid chromatography-mass spectrometry method for metabolite profiling of the glutathione anabolic pathway in esophageal cancer tissues and cells |
| PMC10759355__F1 | Helicobacter pylori infection and Parkinson’s Disease: etiology, pathogenesis and levodopa bioavailability |
| PMC10759449__F8 | Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway |
| PMC10759521__F9 | DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma |
| PMC10759702__F7 | Leukocyte differential gene expression prognostic value for high versus low seizure frequency in temporal lobe epilepsy |
| PMC10759737__F6 | RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding |
| PMC10760828__F9 | Schematic representation of overall outcome of the study |
| PMC10761042__F8 | PTP1B-Cdk3 Signaling Axis Promotes Cell Cycle Progression of Human Glioblastoma Cells through an Rb-E2F Dependent Pathway |
| PMC10770036__F0 | Novel dual inhibitors of PARP and HDAC induce intratumoral STING-mediated antitumor immunity in triple-negative breast cancer |
| PMC10770335__F3 | Regulation mechanisms of KCC2 in mature neurons |
| PMC10774482__F1 | Canonical signaling pathways of cGAS |
| PMC10777970__F7 | Hedgehog (Hh) signaling pathway |
| PMC10778012__F1 | Oncogenic signaling can drive changes in the transcription of tRNA genes |
| PMC10778012__F5 | tRF-mediated translational regulation |
| PMC10778111__F3 | Non-coding (nc)RNA-regulated signaling pathways involved in gastric cancer invasion |
| PMC10778204__F2 | Representation of the important miRNAs that effectively regulate the Notch signaling pathway in glioblastoma |
| PMC10778207__F4 | Src intracellular signaling pathway and various cellular processes controlled by each pathway |
| PMC10778261__F8 | Modulation of PI3K/AKT/TORC1 signaling pathway and AMPK activity downstream of M2 mAChR activation by APE or N8 in U251 and GB7 cell lines |
| PMC10778290__F7 | Schematic diagram shows that tumor-derived ESM1 combines with the c-Met expressed by endothelial cells to promote GC peritoneal metastasis by inducing angiogenesis |
| PMC10778465__F1 | The antitumor effect of SST receptors after ligand binding |
| PMC10778515__F6 | The Rap1 signaling pathway |
| PMC10778571__F3 | Pathways regulated by DKK-3: insights into DKK-3 functions |
| PMC10778705__F3 | cGAS-STING antitumoral and protumoral mechanisms |
| PMC10778733__F3 | Visualization of CAC-related genes and their functional cross-talks |
| PMC10778733__F7 | PPI is related to adipocytokine signaling |
| PMC10778864__F2 | VEGF-VEGFR signaling pathway |
| PMC10779012__F1 | Metabolism of cholesterol within an ovarian cancer cell |
| PMC10779012__F2 | Insulin-like growth factor 1 (IGF1) signaling pathway and major downstream effects on cancer cells |
| PMC10779012__F3 | Mechanisms by which pitavastatin and metformin act to (A) turn cancer cells sensitive to chemotherapy and (B) help to revert the exhaustion state of CD8+ T cells |
| PMC10779100__F1 | Regulation of osteoclast formation by MERTK and TYRO3 |
| PMC10779100__F2 | TAM receptors and their downstream signaling pathways in osteoblasts |
| PMC10779133__F1 | Ketogenic and ketolytic pathways in the liver and brain cells |
| PMC10779133__F2 | Neuroprotective effects of KBs and KD by providing energy source and improving mitochondrial dysfunction in the brain |
| PMC10779133__F3 | Signaling functions of KBs and KD for anti-apoptosis, antioxidant defense, and epigenetic and post-translational modifications |
| PMC10779133__F4 | Signaling functions of KBs and KD for anti-neuroinflammation and autophagic flux |
| PMC10779157__F3 | SHP-1-mediated inhibition of the JAK/STAT signaling pathway |
| PMC10779188__F1 | BRAF signaling pathway and targeted therapies in the BRAF pathway |
| PMC10779236__F4 | Main molecular mechanisms regulated by sialic acid |
| PMC10779236__F5 | Possible action mechanisms of sialic acid mediated by the signaling pathway and gut environment |
| PMC10779351__F2 | NADPH Production Pathways in Cells |
| PMC10779351__F3 | NADPH in Insulin Secretion from Pancreatic Beta-Cells |
| PMC10779351__F4 | Illustration of Insulin Signaling and Resistance Pathways |
| PMC10779351__F5 | Illustration of Ferroptosis in Pancreatic Beta Cells and Its Relation to NADPH |
| PMC10779434__F2 | The actin cytoskeleton within the foot processes |
| PMC10779699__F2 | Proposed model for the pathogenic role of the NLRP3 inflammasome signaling pathway in RA and its clinical implications as the therapeutic potential |
| PMC10779870__F11 | KEGG TNFA signaling and its association with the PI3K-AKT signaling pathway |
| PMC10779870__F13 | Proposed molecular effects of fucoxanthin through modulation of genes and proteins of the PI3K-AKT signaling pathway in TNF-Alpha-stimulated MDA-MB-231 and MDA-MB-468 cells |
| PMC10779880__F4 | Mechanisms of treatment of neurodegenerative diseases (NDs) using capsaicin and N-oleoyldopamin (OLDA) |
| PMC10780299__F3 | Saponins activate the TLRs signaling pathway through TLRs, upregulate class I and II MHC molecules in APCs, and promote antigen capture, processing, and presentation |
| PMC10780299__F4 | Activation of the NFKB/MAPK signaling pathway by saponins regulates the expression of a series of immune-related cytokines, NO, surface-stimulating factors, and mRNAs and/or proteins of the cell cycle |
| PMC10780960__F3 | Comparative analysis of differentially methylated regions and differentially expressed genes in the metabolism pathways related to sink-source regulation |
| PMC10784739__F7 | TIFA regulating the inflammatory and osteoclast differentiation in the RAW264 |
| PMC10788715__F5 | MiRNA-766-3p inhibited gastric cancer via targeting COL1A1 and regulating the PI3K/AKT signaling pathway |
| PMC10789540__F5 | IFITM3-mediated activation of TRAF6/MAPK/AP-1 pathways induces acquired TKI resistance in clear cell renal cell carcinoma |
| PMC10792990__F4 | Mechanism of GB on independent risk factors for atherosclerosis |
| PMC10796096__F1 | cGAS-STING signaling pathway in amyotrophic lateral sclerosis (ALS) |
| PMC10796102__F3 | Possible mechanisms of co-occurring neuroinflammatory response and brain edema in patients with hepatic encephalopathy and potential therapeutic targets for hepatic encephalopathy |
| PMC10796102__F4 | Binding of CCL19/CCL21 to CCR7 activated signaling pathways in tumor cells, including PI3/Akt, MAPK/ERK and Jak/STAT, which enhanced the expression of VEGF-C and thus promoted lymphangiogenesis |
| PMC10796102__F5 | Communication between the gastrointestinal tract and cerebral lymphatic system is mediated directly and indirectly by immune, neural and endocrine pathways |
| PMC10796102__F6 | Action of cerebral lymphatic system in brain diseases due to impaired renal function |
| PMC10796104__F1 | Mechanisms of Janus Kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) in chronic pain |
| PMC10804064__F2 | Comprehensive Review of the Key Characteristics of the Genus Mentha, Natural Compounds and Biotechnological Approaches for the Production of Secondary Metabolites |
| PMC10807637__F6 | HDAC inhibitors target IRS4 to enhance anti-AR therapy in AR-positive triple-negative breast cancer |
| PMC10809359__F7 | PPI network of the signalling molecules regulating macrophage activity and HIF-1 signalling pathways |
| PMC10812436__F3 | Main anti-inflammatory properties of HDLs |
| PMC10813042__F3 | Antioxidant mechanism of estrodiol |
| PMC10813163__F1 | Schematic illustration of leptin-induced signaling pathways |
| PMC10813482__F1 | DNA modification of MSCs in SONFH |
| PMC10813560__F8 | Heatmaps were generated to visualise the notable pathways identified as significant by DIANA-miRPath (v |
| PMC10813911__F3 | Astroglial Cells: Emerging Therapeutic Targets in the Management of Traumatic Brain Injury |
| PMC10814071__F4 | Regulatory Gene Network Associated with the Ameliorative Effect of Oat Antibacterial Peptides on Rat Colitis |
| PMC10814159__F3 | MDM2 and CDK4 pathway regulation |
| PMC10814159__F5 | Activation of the Hh/GLI signaling pathway |
| PMC10814280__F1 | RABV-induced incomplete autophagy |
| PMC10814280__F2 | : promotion : inhabition |
| PMC10814950__F8 | Key signalling pathways targeted by a combination of PI3Ki (PIK-75) and CDKi (dinaciclib) |
| PMC10814963__F2 | Common mechanisms of melanoma progression and treatment resistance |
| PMC10814963__F4 | Proposed model for Fyn-CD133 signaling to the PI3K pathway induces melanoma intrinsic and acquired resistance to anti-cancer agent in melanoma cells |
| PMC10815168__F1 | Schematic diagram depicting the miRNA signaling pathways activated by aldosterone through the MR |
| PMC10815231__F2 | Therapeutic implications of miRNAs and lncRNAs in AKI |
| PMC10815231__F3 | Action of ncRNAs in CKD |
| PMC10815231__F4 | Graphical summary of the mechanisms of action of miRNAs and lncRNAs in DKD |
| PMC10815231__F5 | Graphical summary of the mechanisms of action of microRNAs and lncRNAs in renal fibrosis |
| PMC10815326__F7 | Different patterns of inflammatory gene activation in cerebral cortex and cerebellum of Npc1−/− mice |
| PMC10815547__F8 | Scheme of the ginsenoside biosynthetic pathway in ginseng according to Li et al |
| PMC10815595__F1 | HBV-HCC pathways of top 10 downregulated miRNAs |
| PMC10815595__F2 | HBV-HCC pathways of top 10 upregulated miRNA |
| PMC10815665__F2 | CXCR signaling pathway |
| PMC10815665__F3 | Proposed conceptual framework for the involvement of CXCR signaling in modulating Th1/Th17-driven pathologies |
| PMC10815772__F1 | FGF/FGFR and downstream signaling pathway |
| PMC10815772__F2 | Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers |
| PMC10816037__F1 | Different signaling pathways affected by the probiotic strains with anti-obesity or anti-diabetic properties in C |
| PMC10816189__F5 | Cell cycle metabolic pathway, with Zhuansihao serving as the control and 071113 as the experimental group |
| PMC10816189__F6 | Plant hormone signal transduction pathway, with Zhuansihao serving as the control and 071113 as the experimental group |
| PMC10816220__F1 | Transforming growth factor B (TGFB) and bone morphogenetic proteins (BMP) signaling pathway |
| PMC10816282__F6 | Transcription response to APS of the JNK/MAPK (A), JAK/STAT (B), Toll and Imd (C) signaling pathway genes in the control and GagrRNAi females and males |
| PMC10816282__F7 | Proposed scheme for transcriptome stress response to APS |
| PMC10816399__F2 | IL-6R interaction with gp130 for Stat3-mediated inflammatory target gene expression |
| PMC10816532__F3 | Potential mechanisms underlying the inhibitory effects of magnesium on vascular calcification |
| PMC10816780__F15 | Transgenerational Transmission of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Effects in Human Granulosa Cells: The Role of MicroRNAs |
| PMC10816924__F7 | KLF10 in cardiac fibrosis |
| PMC10818625__F1 | Mechanism by which pathogenic infection causes cell necroptosis |
| PMC10818625__F2 | Pharmacological interventions against necroptosis in pneumonia |
| PMC10818876__F2 | Signaling pathways triggered by traditional medicine-derived SCFAs |
| PMC10819295__F2 | Possible signaling pathways activated by ORF8 |
| PMC10819745__F3 | Pattern diagram of immune cell response process triggered by PRR signal triggered by HSV-1 infection |
| PMC10819970__F8 | Engineering CXCL12 biomimetic decoy-integrated versatile immunosuppressive nanoparticle (VIN) for the management of overactivated brain immune microenvironment |
| PMC10820115__F3 | Canonic polyamine biosynthetic pathway of mammals (hosts of trypanosomatids) |
| PMC10820555__F3 | Study on the Pharmacological Mechanism of Icariin for the Treatment of Alzheimer’s Disease Based on Network Pharmacology and Molecular Docking Techniques |
| PMC10820593__F5 | Common adjuvants and proposed mechanisms |
| PMC10820833__F2 | Cellular senescence pathways affected by Tax |
| PMC10821092__F1 | Pharmacology of Veratrum californicum Alkaloids as Hedgehog Pathway Antagonists |
| PMC10825793__F3 | EBV-miRNAs modulating inflammatory signaling pathways |
| PMC1082717__F1 | The mTOR pathway and the potential intersection with LMP2A-activated PI3-kinase/Akt signaling |
| PMC10831399__F3 | NRP-1 gene expression generating axis of stem-cell properties |
| PMC10831402__F2 | Suggested PML/RARA-related signaling pathway that leads to cell proliferation and the evasion of apoptosis |
| PMC10834963__F8 | Proposed signaling mechanism for the effects of amlexanox on LPS-induced neuroinflammation in BV2 microglial cells |
| PMC10834974__F5 | Novel preliminary metabolomic panel for IHD diagnostics and pathogenesis |
| PMC10835843__F8 | Expression heat map of related genes and metabolites in phenylpropane biosynthesis, ascorbic acid, succinic acid and glutamic acid metabolic pathway |
| PMC10835878__F10 | Mechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells |
| PMC10836028__F9 | Schematic figure showing that melatonin attenuates mechanical trauma-induced hepatic injury by inhibiting IP3R1-mediated MAMs formation via activating the melatonin receptor-ERK1/2-FoxO1 pathway |
| PMC10836493__F3 | Mechanism by which GPX3 is involved in maintaining the stemness of OCSCs in the TME |
| PMC1083688__F2 | Curbing the nuclear activities of Beta-catenin |
| PMC10837142__F5 | Terpenoid biosynthesis pathway in T |
| PMC10837142__F6 | Common symbiosis signalling pathway in T |
| PMC10837142__F7 | Peroxisome biogenesis pathway in T |
| PMC10838060__F1 | Molecular mechanism of the cGAS-STING pathway |
| PMC10838060__F10 | CGAS-STING by metal ions |
| PMC10838060__F2 | cGAS-STING pathway and the NFKB pathway |
| PMC10838060__F3 | cGAS-STING and JAK–STAT pathways |
| PMC10838060__F4 | Other media for activating STING |
| PMC10838060__F6 | cGAS-STING and pyroptosis |
| PMC10838060__F7 | cGAS-STING pathway and metabolic reprogramming |
| PMC10838060__F8 | cGAS-STING and cell senescence in diabetes |
| PMC10838060__F9 | CGAS-STING pathway in diabetic complications |
| PMC10838202__F5 | mRNA-seq results of KEGG pathway enrichment analysis and western blot results |
| PMC10838448__F2 | RANKL/RANK signaling pathway activates NFATc1 |
| PMC10838672__F1 | VEGF protein family and receptor signaling pathway |
| PMC10838672__F2 | RTKs and its related downstream signaling pathways and their targeted therapies for hepatocellular carcinoma |
| PMC10838672__F3 | PI3K/AKT/mTOR signaling pathway and targeted inhibitors |
| PMC10838672__F4 | Wnt on and Wnt off state of Wnt/B‐catenin signaling pathway and therapeutic strategies based on them |
| PMC10838672__F5 | JAK/STAT signaling and targeted inhibitors |
| PMC10838672__F6 | Smo‐driven canonical Hh signaling pathway and targeted inhibitors |
| PMC1083933__F2 | Cell cycle trials in Salamanca |
| PMC10840486__F9 | Schematic illustration showing synergistic calcium supplementation and SIM delivery strategy for osteoporosis |
| PMC10840489__F3 | Endosomal and cytoplasmic viral RNA sensing by RLRs and TLRs |
| PMC10840523__F1 | Therapeutic Potential of Fingolimod in Diabetes Mellitus and Its Chronic Complications |
| PMC10843903__F6 | Increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development: A pilot study |
| PMC10844198__F2 | Putative NFKB signaling pathway data mined from Euprymna scolopes reference transcriptome and genome |
| PMC10844364__F1 | Main functions and metabolic origins of novel acylations |
| PMC10844364__F2 | Novel acylations participate in head and neck cancer metastasis |
| PMC10844364__F4 | Novel acylations act as significant regulators in HCC metastasis |
| PMC10845297__F3 | Fibroblasts of metastatic organ in PMN formation |
| PMC10845554__F1 | IL-17-producing Treg differentiation |
| PMC10845654__F8 | Working model |
| PMC10845928__F1 | Immunologic properties of cancer stem cells (CSCs) |
| PMC10845928__F2 | Ferroptosis in CSCs |
| PMC10845928__F3 | Mechanisms underlying radio-resistance in CSCs |
| PMC10845928__F4 | Mechanisms underlying chemoresistance in lung CSCs |
| PMC10846380__F6 | CK1A degradation by FPFT-2216 and subsequent p53 pathway activation and CBM complex/NFKB pathway inhibition |
| PMC10846991__F3 | Interleukin-6 (IL-6) signaling pathway |
| PMC10846991__F4 | Overall signaling pathways between podocytes and glomerular endothelial cells (GECs) |
| PMC10848377__F2 | Koetjapic acid molecular mechanism in curbing carcinogenesis |
| PMC10850140__F7 | Exploring the mechanism of action of Sparganii Rhizoma-Curcumae Rhizoma for in treating castration-resistant prostate cancer: a network-based pharmacology and experimental validation study |
| PMC10850268__F1 | Signaling pathway of insulin action and the selective impairment of insulin receptor substrate (IRS)-protein kinase B (Akt) signaling pathway in insulin resistance |
| PMC10850749__S1 | Garcinone C attenuates RANKL-induced osteoclast differentiation and oxidative stress by activating Nrf2/HO-1 and inhibiting the NF-kB signaling pathway |
| PMC10851565__F3 | Autophagy’s dual-edge effect on NF-KB and PI resistance |
| PMC10851593__F4 | Lignin synthesis pathway map |
| PMC10853261__F8 | Proposed model of GC-induced adiposity |
| PMC10853543__F4 | SOX TFs acts as the hub of signaling pathways in the tumorigenesis |
| PMC10853571__F2 | The pharmacological mechanism of fluoxetine in astrocytes |
| PMC10853571__F3 | Molecular signaling schematic of cytokine hypothesis in the pathogenesis of MDD |
| PMC10853571__F6 | Molecular mechanisms of tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin/norepinephrine reuptake inhibitors (SNRIs) and ketamine |
| PMC10853679__F7 | Graphical abstract to present metabolic heterogeneity in central and peripheral tumour areas of LumA and LumB |
| PMC10854112__F10 | Schematic showing the preliminary mechanism of Gnao1 in SCs regulating SC differentiation and myelination |
| PMC10854459__F8 | Anticancer role of JAC in AGS cells |
| PMC10854592__F2 | STAT3 signaling pathway: STAT3 activation is initiated by upstream activity including ligand binding by (a) cytokines (IL-6 and non-IL-6 family members), (b) growth factors (EGF, FGF, etc |
| PMC10854597__F8 | FAK signaling in FLNC cardiomyopathy |
| PMC10854678__F9 | Arf6 signaling pathway, the inhibitors used in this study, and a model of MuLV Gag release |
| PMC10854699__F2 | Cachexia-related pathways in skeletal muscle: The mTOR (mechanistic Target of Rapamycin) signaling pathway, which is initiated by activated Akt and inhibits the phosphorylation of FoxO, facilitates the process of protein synthesis |
| PMC10854713__F3 | Phosphorylation regulates EMT and other functions of CRC cells |
| PMC10854713__F5 | Glycosylation regulates the metastasis of CRC cells |
| PMC10854734__F5 | SADS-CoV infection induces apoptosis and complete autophagy |
| PMC10854812__F10 | Selected agents targeting the Fyn/CD133/PI3K/Akt/mTOR pathway |
| PMC10854812__F5 | Function of CD133 protein |
| PMC10854812__F8 | Models of both non-receptor tyrosine kinase- (NRTKs) and receptor tyrosine kinase-mediated signaling pathways in tumor progression and drug resistance |
| PMC10854812__F9 | Downstream effectors of RTK-mediated pathways and their biological consequences |
| PMC10854888__F1 | HSP in biochemical functions of cells |
| PMC10854933__F2 | An illustration of the theoretical modes of action of the MRGPRX2 signaling pathway inhibitors |
| PMC10855445__F3 | Interaction between ALR, NLR, and cGLR (cGAS/STING signaling pathway) |
| PMC10855599__F2 | JAK-STAT signaling pathway and PI3K-AKT signaling pathway that affect AD |
| PMC10855920__F2 | Innate and adaptative immune systems |
| PMC10855920__F4 | Molecular pathways hypothesized to be involved in the pathogenesis of nonspecific orbital inflammation |
| PMC10855951__F5 | Transcriptomic Analysis Provides Insights into Candidate Genes and Molecular Pathways Involved in Growth of Mytilus coruscus Larvae |
| PMC10856016__F2 | Phosphatidylinositol 3-kinase (PI3K) protein kinase B (AKT)/mammalian target of rapamycin (mTOR), PI3K/AKT/mTOR, and mitogen-activated protein kinase (MAPK) signaling pathway activation in gastric cancer (GC) |
| PMC10857159__F6 | Expression of DEGs involved in the plant hormone signal transduction pathway of M |
| PMC10857240__F1 | Proteins and genes involved in chlorophyll synthesis pathway |
| PMC10857877__F6 | RND3 induction and interaction with TLR4 and IFNG receptor signaling in activated proinflammatory macrophages |
| PMC10859375__F5 | Lipid laden macrophage accumulation in the p |
| PMC10860311__F1 | Ovarian clear cell cancer carcinogenesis |
| PMC10860821__F1 | Three types of pyroptosis pathway |
| PMC10860821__F3 | OA is a condition that involves the breakdown of cartilage in the joints |
| PMC10861537__F7 | Summary: impact of chemotherapy on CAF-S1 and CD8 T cell density in HGSOC |
| PMC10861954__F3 | Unfolded Protein Response |
| PMC10861954__F4 | Apoptosis and Inflammatory Signal Pathways Associated with Unremitted ER Stress and UPR |
| PMC10862883__F5 | Acceleration within PREs widely affects the Notch signaling pathway |
| PMC10864729__F6 | Predicted downstream pathway of MIR17HG |
| PMC10865100__F1 | Classical model of G1–S transition regulated by cyclins and cyclin-dependent kinases (CDK) |
| PMC10865172__F3 | Roles and mechanisms of ESM1 in tumor angiogenesis |
| PMC10865418__F5 | Schematic diagram illustrating the hypothesis of signaling regulation in aGVHD |
| PMC10865529__F5 | Phenolic metabolic pathways and associated network diagrams |
| PMC10865661__F15 | Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IKKB/NFKB p65 signaling pathway: insights from in silico and in vivo investigations |
| PMC10866157__F6 | Schematic diagram depicting the mechanisms of 5-aza-dC treatment in inhibiting choroidal neovascularization in a laser-induced mouse model |
| PMC10866657__F2 | BMP9-10/ENG/ALK1/SMAD4 signaling pathway maintains vascular quiescence by repressing angiogenic pathways |
| PMC10866932__F7 | SALL4 promotes cancer stem-like cell phenotype and radioresistance in oral squamous cell carcinomas via methyltransferase-like 3-mediated m6A modification |
| PMC10867181__F3 | Hypoxia regulates the metastatic cascade |
| PMC10867724__F4 | Demonstration of the TNF signaling pathway and the target to be tested |
| PMC10869077__F9 | TNF signaling pathway |
| PMC10869406__F5 | Relationship between major genes and the PI3K/AKT/mTOR signaling pathway |
| PMC10869479__F3 | P2X7-mediated signaling pathway |
| PMC10869786__F7 | The mechanism by which FXR promotes NSCLC metastasis |
| PMC10869798__F2 | Microglial activation and neurodegeneration |
| PMC10869801__F0 | Macrophage TSC1-mediated AKT/MST1/NRF2 signaling pathway in I/R-triggered liver inflammation |
| PMC10870057__F1 | Molecular regulatory mechanism of dormant cancer cells |
| PMC10870057__F2 | Molecular regulatory mechanisms of dormant PGCCs |
| PMC10870461__F16 | Signal pathways related to CALD1 mapped by KEGG database |
| PMC10871146__F1 | Hydrogen maintains an anaerobic environment in the intestine and reduces oxidative damage via selective antioxidant effects |
| PMC1087229__F8 | Signaling pathway of NGF-induced neurite outgrowth in PC12 cells |
| PMC10873211__F9 | Nasal Administration of bFGF-Loaded Nanoliposomes Attenuates Neuronal Injury and Cognitive Deficits in Mice with Vascular Dementia Induced by Repeated Cerebral Ischemia‒Reperfusion |
| PMC10873402__F4 | Enrichment analysis for leading target genes |
| PMC10873402__F5 | JAK-STAT signaling pathway |
| PMC10873884__F3 | Different self-incompatibility systems |
| PMC10874285__F1 | HCV inhibits the innate immune response |
| PMC10874285__F2 | Interplay between HCV-induced autophagy and host innate immune response |
| PMC10874461__F2 | X-linked osteoporosis in males |
| PMC10874461__F5 | Pathological mechanisms of osteoporosis induced by diabetes, glucocorticoids, and psychological stress |
| PMC10874556__F1 | Mechanical cue-dependent scarring |
| PMC10874560__F3 | Representative bacterial-origin immunostimulants signaling pathway |
| PMC10874582__F2 | Immune-related signalling pathways in mosquitos |
| PMC10874752__F13 | miR-140-y targets TCF4 to regulate the Wnt signaling pathway and promote embryonic feather follicle development in Hungarian white goose |
| PMC10875024__F6 | CCN3 involvement in cell apoptosis and FGFR2 signaling pathways |
| PMC10875024__F8 | Key signaling pathways regulating stem cell pluripotency |
| PMC10875036__F5 | IAV NS1 and SARS-CoV-2 Nsp1 antagonism of innate immune responses |
| PMC10875059__F1 | Metabolic pathway of risperidone |
| PMC10875059__F3 | Pharmacogenomics and non-genetic factors affecting drug response in autism spectrum disorder in Thai and other populations: current evidence and future implications |
| PMC1087506__F8 | IRAK1 functions in the TLR and IL-1B pathway upstream of convergence with the TNFA pathway |
| PMC10875085__F1 | Mechanisms for S protein-induced lung injury |
| PMC10875085__F2 | Mechanisms for E protein-induced lung injury |
| PMC10875826__F1 | (i) ERBB/HER family members and their cognate ligands (ii) Structural difference of various (I-VI) types of NRG1 |
| PMC1087583__F5 | The secretory pathway and UPR under different conditions |
| PMC10875894__F8 | VNP-shCCDC25 blocking CCDC25-NET-DNA and remodeling immunity in B16F10-bearing mice and 4T1-bearing mice |
| PMC10876307__F5 | Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells |
| PMC10876676__F2 | Upon infection with HIV, the virus infiltrates cluster differentiation positive (CD4+) T-lymphocytes and induce pro-inflammatory intracellular micro-environment marked by increased ILB |
| PMC10876703__F7 | TEAD1 promotes the fibroblast-to-myofibroblast transition during TAC or Ang-II-induced pathological cardiac remodelling through the Wnt signalling pathway |
| PMC1087795__F1 | Schematic depiction of the S |
| PMC10878139__F3 | Cross-talk between glucocorticoid receptor and YAP/TAZ signaling pathways |
| PMC10878139__F4 | Cross-talk between glucocorticoid receptor and Wnt signaling pathways |
| PMC10878139__F5 | TGFB signaling pathway mediates the effect of the GR signaling pathway in the TM |
| PMC10878147__F1 | Illustration represents the polyphenols targeting the NFKB pathway associated with Alzheimer's disease |
| PMC10878151__F1 | Structure of the SMAD family and overview of TGFB/SMAD and BMP/SMAD signaling pathway |
| PMC10878151__F2 | Crosstalk between TGF‑B/SMAD and other pathways |
| PMC10878151__F4 | Phosphorylated SMAD2/3 signaling pathways regulate the process of HCC |
| PMC10878789__F10 | Schematic diagram illustrating the occurrence of asthma |
| PMC10879038__F3 | GSK‐3B as a converging point in key signaling pathways regulating BBB integrity post‐stroke |
| PMC10879038__F4 | Programmed endothelial cell death pathways |
| PMC10879340__F4 | Zebrafish Studies on TGFB Signaling and Pharyngeal Arch Patterning |
| PMC10879484__F7 | Predicted activation of macrophage classical activation signaling pathway in parenteral nutrition piglets |
| PMC10879484__F8 | Therapeutics identified as strongly inhibited upstream regulators in Ingenuity Pathway Analysis |
| PMC10879531__F6 | Mechanism of action of Gal-3 in the A-ED through the TLR4/MyD88/NFKB pathway |
| PMC10879685__F2 | NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy |
| PMC1088000__F4 | In Silico Analysis of the L |
| PMC10880550__F1 | Effect of acetylcholine released from cholinergic neuron on heart, visceral smooth muscles and the brain |
| PMC10880550__F5 | Complex interactions among GIRK, TRPC1/4/5 and KCNQ channels with GPCRs via G proteins A or BG subunits and PIP2 in neurons |
| PMC10881233__F2 | Action of cryoablation combined with immune checkpoint blockers |
| PMC108819__F8 | Signalling pathways for EGF activation of c-jun |
| PMC10882078__F7 | TNF signaling pathway in atherosclerosis-related and non-related to CKD |
| PMC10882095__F5 | Immune molecule interaction network in the blood and heart tissues of chronic Chagas disease (CCC) patients |
| PMC10882314__F2 | Emerging role of SENP1 in tumorigenesis and cancer therapy |
| PMC10883245__F8 | DOCK7 in EVs mediates intercellular communication between TAMs and CRC cells |
| PMC1088370__F1 | Topologies of the three networks |
| PMC10884126__F8 | Interaction networks of “pathways-differentially expressed lncRNAs-target genes” |
| PMC10884763__F3 | Illustrative representation of molecular mechanisms of obesity-induced non-communicable diseases |
| PMC10884763__F5 | WATME-specific immunotherapy for obesity-induced coronary heart disease (CHD) |
| PMC10884928__F1 | NAD metabolic therapy in metabolic dysfunction-associated steatotic liver disease: Possible roles of gut microbiota |
| PMC10884928__F3 | Prevotella along with NR supplements improving the signaling pathway of BCAA metabolism in MASLDNAD precursor supplements can affect fatty acid oxidation and lipid synthesis as well as the TCA cycle and insulin sensitivity |
| PMC10885697__F2 | MAPKs signaling is obligatory for male reproductive function in a development-specific manner |
| PMC10885964__F2 | Advancements in Genetic Marker Exploration for Livestock Vertebral Traits with a Focus on China |
| PMC10886007__F2 | Mitochondria-dependent apoptosis pathway |
| PMC10886007__F3 | TGFB/SMAD signaling pathway |
| PMC10886007__F4 | AMPK/SIRT1/PGC-1A signaling pathway |
| PMC10886007__F5 | PI3K/Akt/mTOR signaling pathway |
| PMC10886030__F4 | Oxidative inactivation of PTEN in insulin-related metabolism and muscle differentiation |
| PMC10886137__F4 | JNK and p38 MAPK signaling pathway of filefish upon Cd exposure |
| PMC10886137__F5 | Glycolysis pathway of filefish upon Cd exposure |
| PMC10886137__F6 | Fatty acid degradation-related pathways of filefish upon Cd exposure |
| PMC10886137__F7 | Citrate cycle (TCA cycle) pathway of filefish upon Cd exposure |
| PMC10886236__F4 | Heatmap of the pathway of glycolysis, antioxidant enzymes, and ascorbate–glutathione cycle |
| PMC10886332__F3 | Co-expression network for the PP group based on lncRNA key regulators |
| PMC10886467__F1 | Relevant signaling pathway potentially being involved in the pathogenesis of polycystic kidney disease (PKD) and/or chronic kidney disease (CKD) |
| PMC10886467__F2 | An illustrative representation and overview of PINK1, Parkin, and related molecules in the regulatory pathway for mitophagy |
| PMC10886574__F2 | The SIRT1–c-Myc axis in the control of stem cells |
| PMC10886574__F3 | Sirtuins Affect Cancer Stem Cells via Epigenetic Regulation of Autophagy |
| PMC10886582__F3 | Pathways related to activation of pyroptosis |
| PMC10886582__F4 | Necroptosis signaling pathway |
| PMC10886830__F7 | Toll-like receptor (TLR) signaling pathway with a focus on TLR4 |
| PMC10886920__F1 | Signaling Pathways of AXL Receptor Tyrosine Kinase Contribute to the Pathogenetic Mechanisms of Glioblastoma |
| PMC10887009__F4 | MR suppresses gastric cancer development by inhibiting GSCSs |
| PMC10887023__F2 | Gene interaction network of dyslexia and stress-associated genes |
| PMC10887079__F1 | Nrf2 signaling pathway |
| PMC10887103__F5 | Defective PI3K/Akt pathway in T2DM results in insulin resistance and the activation of the pro-inflammatory, pro-apoptotic inhibition of eNOS and glycogen production |
| PMC10887144__F1 | In vitro liver organoid model creation |
| PMC10887252__F5 | Molecular mechanisms for the involvement of the JNK pathway in insulin resistance |
| PMC10887283__F2 | Therapeutic potential of anti-IL-1 agents in hidradenitis suppurativa |
| PMC10887358__F2 | Signaling pathways of B cell receptor (BCR) |
| PMC10888037__F8 | Schematic diagram showing the potential pathways which were more active in non-mucilage BS |
| PMC10888202__F6 | Comparative analysis of DEGs at different growth stages |
| PMC10888344__F9 | Molecular mechanism that drives the positive impact of CSE in OVA-induced AR mouse model |
| PMC10888452__F1 | The PI3K/AKT signaling pathway and its activation |
| PMC10888650__F1 | Potassium’s (K+) Role in Various Cellular Processes |
| PMC10888650__F4 | ABCC8 Expression in Hypoxic and Inflammatory Conditions |
| PMC10888664__F2 | Evolution of CRC |
| PMC108887__F9 | The CD5-induced signaling pathway, which is mediated by PI 3-kinase and Vav, resulting in the activation of Rac1 |
| PMC10889086__F1 | Bruton’s Tyrosine Kinase Inhibitors: Recent Updates |
| PMC10889199__F1 | Endothelial cell senescence |
| PMC10889208__F1 | Heterogeneity of the dermal fibroblast population |
| PMC10889501__F4 | Postulated relationship between IL-1B/IL-1RA axis and autophagy signaling pathway in invasive bladder cancer |
| PMC10889522__F6 | Schematic illustration of YTHDF2 mediating the action of BDNF stimulating the proliferation of porcine follicle granulosa cells |
| PMC10889780__F9 | Putative roles of glutathione and AP-1 in the cooperation between VDDs and Nrf2 activators in inducing differentiation of AML cells |
| PMC10889827__F1 | BMP signaling represents a fundamental signaling profile in periosteal effects |
| PMC10889827__F2 | PDGF signaling mediates periosteal activation and blocks BMP2-induced osteogenesis |
| PMC10889827__F3 | Ihh signaling plays a critical role in periosteal bone biology and shows complex interaction with other molecules |
| PMC10889827__F4 | Wnt signaling has important indirect as well as direct effects on PDCs |
| PMC10891054__F9 | PART1/AC007728 |
| PMC10891274__F1 | YAP/TAZ activity is tightly regulated via Hippo signaling |
| PMC10891274__F2 | YAP/TAZ in fibroblast-like synovial cells (FLS) and its related signaling pathway involved in RA |
| PMC10891858__F1 | Investigating the Role of Non-Coding RNA in Non-Alcoholic Fatty Liver Disease |
| PMC10891858__F4 | Major signaling pathways by ncRNA in NAFLD/NASH as discussed in the text (Created with BioRender |
| PMC10892304__F6 | Protein–protein interaction (PPI) network in biosynthesis of plant hormones and signal transduction pathways |
| PMC10892344__F6 | Schematic diagram generated by IPA of the death receptor signaling pathway with which the DEPs with |FC| ≥ 1 |
| PMC10892479__F1 | NFKB signaling (canonical and non-canonical) pathways |
| PMC10892479__F2 | Activation of the NF-kB signaling pathway induced by SARS-Co-V-2 and mediated by RIP/TRAF-dependent pathways or RIP-dependent/TRAF-independent IKKB activation |
| PMC10892479__F4 | Cytokine storm induced by SARS-CoV-2 proteins (ORF7a, ORF3A, M, and N proteins) mediated by the activation of NF-kB |
| PMC10892479__F5 | Illustrates a diagrammatic representation of the intracellular signaling pathways activated by SARS-CoV-2 infection |
| PMC10892755__F1 | Cholesterol and isoprenoid synthesis pathway illustrating how statins inhibit the enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase |
| PMC10893548__F7 | NMN promotes hair growth by regulating the paracrine system of cells |
| PMC10893629__F4 | Frequently altered signaling pathways in SCLC |
| PMC10894496__F8 | Optimized New Shengmai Powder modulation of cAMP/Rap1A signaling pathway attenuates myocardial fibrosis in heart failure |
| PMC10894836__F2 | MiRNAs on gliogenesis |
| PMC10894836__F4 | MiRNAs in Müller cells on retinal regeneration |
| PMC10895590__F6 | Immunorecognition of RNA/DNA fiber NANPs via the cGAS-STING signaling pathway can be regulated through functionalization with aptamers |
| PMC10896604__F4 | Metabolic pathways involved in rectal cancer radioresistance, including significantly upregulated (marked in red) and downregulated (marked in green) abundances of proteins and metabolites in poor responders tumor tissues |
| PMC10896652__F1 | Relationship between NGF/TrKA signaling pathway and KOA peripheral hyperalgesia |
| PMC10896898__F3 | Recreated RAS signaling pathway |
| PMC10896898__F4 | Mixed and gene only representations of the original KEGG pathway |
| PMC10897204__F6 | Newly identified APA-linked cancer susceptibility genes are enriched in metabolic reprogramming and apoptosis-related pathways |
| PMC10897999__F1 | Roles of circRNAs involving interaction with RBPs or other proteins in GC |
| PMC10897999__F3 | CircRNAs work as translational templates to contribute to the proliferation and progression of GC |
| PMC10898159__F1 | Gene and epigenetic regulations of KIT expression in GIST |
| PMC10898159__F2 | Regulations in KIT protein and signaling pathway |
| PMC10898159__F3 | Mechanism of action of existing drugs targeting KIT expression and mutations |
| PMC10898168__S1 | Inhalable hybrid nanovaccines (NVRBD-MLipo) with virus-biomimetic structure against SARS-CoV-2 infection |
| PMC10898204__F5 | KLF participates in the pyroptosis process of ulcerative enteritis through positive regulation of TXNIP/NLRP3 pathway |
| PMC10899349__F1 | IGF1/IGF1R axis and its downstream signaling pathway |
| PMC10900617__F8 | ZnONPs disrupt lysosome activity and impair autophagic flux to facilitate exosome secretion in keratinocytes and macrophages |
| PMC10902128__F4 | TGFB signaling pathway |
| PMC10902464__F1 | Galactose metabolism and CG pathophysiology |
| PMC10902513__F2 | TGFB/Smad signaling pathway involved in radiation skin fibrosis |
| PMC10903154__F1 | Hippo signaling pathway and its network |
| PMC10903154__F4 | Hippo pathway dysregulation from pancreas precursor lesions to malignancy |
| PMC10903931__F1 | Hepatic phospholipid biosynthesis pathways |
| PMC10903931__F4 | Apoptosis model induced by fatty acid metabolism |
| PMC10903931__F5 | LXR-LPCAT3-ERS signaling pathway |
| PMC10904539__F2 | AhR in tumor energy metabolism |
| PMC10905161__F2 | Nrf2/Keap1 signaling pathway |
| PMC10905894__F4 | Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation |
| PMC10906782__F8 | Different biological activities of DCV-derived soluble CPE and sEV-CPE |
| PMC10907440__F2 | Positive effects of SGK1 in embryogenesis |
| PMC10907606__F8 | Hypothetical model showing the role of OAT in IPF pathogenesis |
| PMC10907749__F1 | Host immune responses to T. gondii infection |
| PMC10907749__F2 | Antagonizing the host immune response by T. gondii |
| PMC10907749__F4 | T. gondii antigen alters the signaling pathway of the host cell |
| PMC10908104__F2 | ALS disease pathological signaling pathway |
| PMC10909944__F9 | Mechanistic schematic model of action of circRNA_SLC8A1 in macrophages against Mtb infection |
| PMC10909982__F5 | Wnt/Beta-catenin signaling pathway potentially contributes to PTC progress |
| PMC10910037__F2 | Crosstalk between NFKB signaling and other signaling pathways |
| PMC10910240__F7 | Mechanism of aerobic exercise combined with canagliflozin therapy against ISO-induced CHFCanagliflozin combined with aerobic exercise therapy modulates protein kinase activity |
| PMC10910709__F9 | Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis |
| PMC10910747__F8 | Working model: BMP9/BMP10/ALK1/SMAD4 Signaling drives the regulation of direct and indirect pathways in ECs |
| PMC10910758__F1 | Simplified diagram of the canonical pathway and alternative pathway of the NFKB signalling pathway (Created with BioRender |
| PMC10910758__F4 | NFKB signalling during chondrogenesis in endochondral ossification |
| PMC10910758__F6 | Scheme of FOP pathogenesis and the involvement of NFKB signalling |
| PMC10910758__F7 | Therapeutics of endochondral ossification and FOP targeting NFKB signalling |
| PMC10910842__F2 | Roles of the kinesin-2, 3, 4 family members in HCC |
| PMC10910842__F3 | Roles of the kinesin-5, 6 family members in HCC |
| PMC10910842__F5 | Roles of the kinesin-12, 13, 14 family members in HCC |
| PMC10911275__F4 | FlyBase Pathway Report pages |
| PMC10911341__F9 | Potential mechanisms of inhibiting Perk-ATF4-P21 pathway to enhance the efficacy of MPPAlpha-PDT |
| PMC10912430__F1 | Signaling pathways that may be triggered by cellular oxidation or inflammation during intestinal I/R |
| PMC10912430__F3 | Signaling pathways that may be triggered by cellular apoptosis and necrosis during intestinal I/R |
| PMC10912430__F4 | Signaling pathways that may be triggered by cellular pyroptosis during intestinal I/R |
| PMC10912430__F5 | Signaling pathways that may be triggered by cellular ferroptosis during intestinal I/R |
| PMC10912430__F6 | Signaling pathways that may be triggered by cellular autophagy during intestinal I/R |
| PMC10912471__F1 | Notch signaling pathway |
| PMC10912471__F2 | Notch signaling pathway in tumor immune microenvironment |
| PMC10912719__F2 | DNPNB pathway |
| PMC10912719__F7 | Regulation of DNPNB enzyme clustering and purinosome assembly-disassembly under the control of regulatory proteins and signaling pathways |
| PMC10914313__F7 | The mechanism by which ARM promotes chemoresistance via PPARG/ABCG2 pathway |
| PMC10915131__F6 | Working model for the role of the mechanistic target of rapamycin complex 1 (mTORC1) and its regulated macroautophagy in the induction of cardiomyocyte necroptosis by large doses of isoproterenol (ISO) |
| PMC10915323__F1 | Leveraging molecular targeted drugs and immune checkpoint inhibitors treat advanced thyroid carcinoma to achieve thyroid carcinoma redifferentiation |
| PMC10915378__F6 | Neurodevelopmental and thalamocortical processes involved in epistasis driving spike‐and‐wave discharge (SWD) phenotypes in mice |
| PMC10915940__F1 | Canonical signaling pathway of interferon-gamma |
| PMC10915952__F2 | Small molecule compounds inducing the osteogenic differentiation of mesenchymal stem cells |
| PMC10915952__F3 | The crosstalk between the Wnt and bone morphogenetic protein signaling pathways in osteogenesis |
| PMC10915960__F1 | Preconditioned mesenchymal stem cells with high therapeutic potential in various pathologies |
| PMC10916191__F8 | Working model of lipid synthesis induces by PPAR and cell cycle regulation in GCs after MLN4924 treatment |
| PMC10916417__F6 | Relationship between PS, PC, and PE in the glycerophospholipid metabolic pathway |
| PMC10917537__F1 | Fundamental ferroptosis-related intracellular pathways and mitochondrial regulation |
| PMC10917541__F3 | NMN-mediated longevity and the main reasons for decreasing NAD+ level with age |
| PMC10917649__SF6 | Mapping of the identified gene classes of MetaCyc PWYG-321 mycolate biosynthesis to the KEGG ko00061 fatty acid biosynthesis pathway |
| PMC10917885__F1 | UST treatments specifically target the IL-12/IL-23 signaling pathway |
| PMC10917925__F2 | Pathways included in the model |
| PMC10917928__F1 | TCM polysaccharides’ role in regulating tumor innate immune response |
| PMC10917928__F2 | TCM polysaccharides’ role in regulating tumor adaptive immune response |
| PMC10917964__F3 | Schematic diagram illustrating the promotion of bone formation by incorporating Sr2+ on the surface of titanium-based materials |
| PMC10917983__F2 | Biogenesis and mechanism of miRNAs |
| PMC10917983__F3 | Acrylamide promoted cell apoptosis via the miR-27a-5p-Btf3-ATM-p53 signaling pathway, adapted from Zhang et al |
| PMC10918650__F1 | l-isoleucine biosynthetic pathway in E |
| PMC10918892__F5 | Schematic diagram illustrating the role of miR-223-3p on NLRP3 inflammasome signaling pathway in LPS-induced HTR8/SVneo cells |
| PMC10918910__F1 | Mechanisms through which the gut microbiome contributes to oncogenesis |
| PMC10918910__F2 | AhR activation by microbiome in the tumor microenvironment |
| PMC10919309__F4 | Elucidating the role of Rhodiola rosea L. in sepsis-induced acute lung injury via network pharmacology: emphasis on inflammatory response, oxidative stress, and the PI3K-AKT pathway |
| PMC10919760__F3 | Targeted and immunotherapeutic agents screened in GC PDX and PDO models |
| PMC10920255__F1 | Macrophages participate in mediating inflammatory pain in GA |
| PMC10920255__F2 | Gut bacteria and their metabolites can reach blood vessels, exert local effects in joints, modify macrophage-mediated inflammation and influence GA pain through breaches in the intestinal barrier |
| PMC10920326__F2 | Differential cellular components within the bone marrow microenvironment involved in immune evasion of MM |
| PMC10920911__F3 | Glucose metabolic reprogramming on CRC |
| PMC10920911__F4 | Lipid metabolic reprogramming on CRC |
| PMC10921469__F9 | TRPM4 and TRPM5 mediate Na+ influx upon stimulation with bitter compounds and carbachol (acetylcholine) in parietal cells from the cell line HGT-1 as major signaling pathway |
| PMC10921668__F8 | The early ATL80-dependent response to WDS and its presumed function in retrograde signaling pathways |
| PMC10921743__F10 | AMPK involvement in central sensitization of chronic migraine |
| PMC10922197__F9 | Mechanism by which NBP inhibits osteoclastogenesis is demonstrated |
| PMC10925712__F1 | Schematic biosynthetic pathways of tocopherol and tocotrienol synthesis |
| PMC10925886__F3 | Myeloid cell behaviors and functions by the circadian clock |
| PMC10925886__F4 | Lymphocyte behaviors and functions by the circadian clock |
| PMC10925900__F7 | Amyloid-Beta-Induced Dendritic Spine Elimination Requires Ca2+-Permeable AMPA Receptors, AKAP-Calcineurin-NFAT Signaling, and the NFAT Target Gene Mdm2 |
| PMC10926087__F1 | Activated hedgehog gene pattern correlates with dismal clinical outcome and tumor microenvironment heterogeneity in hepatocellular carcinoma |
| PMC10926276__F5 | Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRB/PI3K/AKT pathway |
| PMC10926624__F2 | Molecular mechanisms of Trp metabolism in gastric cancer |
| PMC10926848__F4 | BCR signaling pathway and BCR-associated CXCR4 signaling in CLL |
| PMC10928192__F1 | TNF/TNFR1 signalling through complex I |
| PMC10928192__F2 | TNF/TNFR1 signalling through complex II |
| PMC10928192__F3 | Interplay between TNF/TNFR1 complex I and complex II signalling pathways |
| PMC10928970__F1 | BRAF gene signaling pathway |
| PMC10929194__F1 | Canonical pathways downstream of KRAS mutations |
| PMC10929194__F3 | Signaling pathways in the TME |
| PMC10929203__F1 | Exosomes in psoriasis pathogenesis |
| PMC10929826__F8 | MUC1 promotes RIF by regulating macrophage ROS-SHP2 signaling pathway to up-regulate inflammatory response and inhibit angiogenesis |
| PMC10930675__F8 | RUNX2 and CXCR4 effects on melanoma cells |
| PMC10930821__F1 | Common intrinsic and extrinsic apoptotic signaling pathways induced by anticancer drugs |
| PMC10930821__F3 | Summary model for the c-Jun N-terminal kinase (JNK)/c-Jun/activator protein 1 (AP-1)-mediated signaling pathway in anticancer drug-induced cell death |
| PMC10930821__F5 | Molecular mechanisms of immunogenic cell death and tumor-specific immune activation via unfolded protein response (UPR) activation by anticancer drugs |
| PMC10930821__F6 | Enhancement of drug sensitivity via molecular therapies targeting tumor growth and antitumor immunity |
| PMC10930964__F1 | Discrete Mechanistic Target of Rapamycin Signaling Pathways, Stem Cells, and Therapeutic Targets |
| PMC10931026__F1 | The polyamine synthesis pathway |
| PMC10931359__F3 | S1PR signaling pathways in liver regeneration and HCC progression |
| PMC10931375__F5 | miRNAs targeting different components of the WNT signaling pathway to promote tumorigenicity |
| PMC10931375__F6 | miRNAs targeting different components of the WNT signaling pathway to inhibit tumorigenicity |
| PMC10931536__F4 | Selected epigenetic changes and host-virus interactions perpetrated by EBV nuclear antigens and latent membrane proteins |
| PMC10931608__F11 | Signaling pathways involving MISP |
| PMC10931645__F2 | Systematic Review of the Advances in the Study of T Lymphocyte Suppressor Receptors in HBV Infection: Potential Therapeutic Targets |
| PMC10931645__F3 | Systematic Review of the Advances in the Study of T Lymphocyte Suppressor Receptors in HBV Infection: Potential Therapeutic Targets |
| PMC10931690__F9 | Diagram depicting the mechanism of neuroprotective effect of siponimod/BAF312 |
| PMC10931763__F8 | “Component–gene–pathway” network |
| PMC10931770__F2 | Positive and negative regulation of osteoclast differentiation |
| PMC10931919__F1 | Origins and intracellular sensors of self-nucleic acids promoting the IFN-I signaling pathway |
| PMC10932085__F1 | TRPs modulate inflammation in immune cells |
| PMC10932085__F2 | TRPs modulate anti-inflammation in immune cells |
| PMC10932453__F2 | Non-coding RNAs in the host response to M |
| PMC10932453__F3 | Immune response of the tracheal mucosa to M |
| PMC10932467__F2 | Possible effects of IL-6 signaling on energy intake and energy expenditure under non-obesogenic conditions |
| PMC10932966__F1 | Two Sphks play different roles |
| PMC10932966__F3 | Distribution of S1P is strictly controlled and involved in innate and adaptive immunity |
| PMC10933033__F1 | Adaptor proteins mediating the signaling of TLR receptors |
| PMC10933033__F2 | TOLLIP-mediated regulation of IL-1R signaling |
| PMC10933033__F3 | Pro-inflammatory cytokine expression by interleukin receptors via STAT and IRF transcription factors |
| PMC10933033__F4 | Adaptor protein SLAP-2 regulates CSF1R-mediated differentiation and survival of macrophages |
| PMC10933339__F9 | Schematic model of the contributor and potential mechanism of KAL in the occurrence and development of NAFLD |
| PMC10933439__F1 | Canonical Activin-, BMP-, and IFN-mediated signaling pathways |
| PMC10933445__F6 | Model depicting the reciprocal interplay between miR-579-3p and MITF in BRAF-mutant melanoma cells through the modulation of MAPK signaling pathway |
| PMC10933535__F1 | Metabolic reprogramming and signalling cross-talks in tumour–immune interaction: a system-level exploration |
| PMC10933834__F9 | Biosynthesis pathway and gene cluster of erythromycin |
| PMC10934027__F6 | Metabolic pathway of terpene biosynthesis |
| PMC10934115__F1 | Genome-wide DNA methylation profiling identifies hypermethylated genes that are linked to regulation of multiple oncogenic signaling pathways in response to resveratrol (RSV) in breast cancer cells |
| PMC10934612__F3 | Gene regulation in fatty acid metabolism pathways by GFIPO compared to WEGG |
| PMC10935043__F7 | Diagram picturing two alternative pathways of sorting damaged mitochondrial components into mitochondrial-derived vesicles |
| PMC10935119__F9 | Enzastaurin, midostaurin, and lestaurtinib |
| PMC10935121__F8 | DEG pathways involved in the sesquiterpene synthesis pathway |
| PMC10935305__F9 | Graphical illustration of the interaction between the gut microbial SCFA-induced Nrf2 redox signaling pathway and LPS/ROS facilitated systemic inflammatory cytokines |
| PMC10935410__F4 | Protein-to-protein subnetworks involved in prolactin, leptin, BDNF, and neurotrophin signaling pathways in CD4+ lymphocytes |
| PMC10937114__F3 | Hypoxia affects adenosine signaling pathways in erythrocytes(A) AMPK-BPGM signaling pathway |
| PMC10937367__F3 | Effect of uridine on disease through O-GlcNAcylation |
| PMC10937391__F9 | Hypotheses on the mechanistical/functional involvement of each microRNA and its potential mRNA targets on OPC differentiation |
| PMC10937431__F3 | Signalling pathways and targets of botanical medicine flavonoids against CIRI-induced autophagy |
| PMC10937431__F4 | Signalling pathways and targets of botanical medicine flavonoids against CIRI-induced PANoptosis and ferroptosis |
| PMC10937442__F8 | Off-label use of Baricitinib improves moderate and severe atopic dermatitis in China through inhibiting MAPK and PI3K/Akt/mTOR pathway via targeting JAK-STAT signaling of CD4+ cells |
| PMC10937455__F1 | The intrinsic immune system in the pathogenesis of GN |
| PMC10937592__F3 | Mechanism of SCFAs madiate a decrease in cholesterol levels |
| PMC10937592__F4 | SCFAs bind with FFAR2, FFAR3 and GPR109A to improve hepatic steatosis, respectively |
| PMC10937592__F5 | Possible mechanisms of SCFAs-induced epigenetic modifications to improve NAFLD |
| PMC10937645__F8 | Proposed model of the recognition of bacteriophage DNA by the animal immune system |
| PMC10937991__F8 | Graphical abstract |
| PMC10938139__F1 | Research progress of periostin and osteoporosis |
| PMC10938139__F2 | Research progress of periostin and osteoporosis |
| PMC10938783__F7 | Multifaceted mechanism of KTC1101 in anti-tumor therapy and immunomodulation |
| PMC10938947__F2 | Introduction of pathways related to bone regeneration, like WNT signaling pathway |
| PMC10938947__F3 | Introduction of pathways related to bone regeneration, like Hedgehog signaling pathway, Notch signaling pathway and FGF signaling pathway |
| PMC10938947__F4 | Introduction of pathways related to bone regeneration, like BMP/TGFBsignaling pathway |
| PMC10939994__F2 | Correlation of HDAC7 and three signaling pathways |
| PMC10940030__F4 | Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases |
| PMC10940142__F1 | Schematic overview describing the target pathway and overall metabolic strategies for heme production |
| PMC10940489__F7 | STAT3 influences cardiac fibrosis through multiple pathways |
| PMC10940631__F3 | Compensatory relationship between the ubiquitin‒proteasome pathway and the autolysosome pathway |
| PMC10940682__F10 | Glycosylphosphatidylinositol anchor proteins (GPI-APs) play a role in several cellular signal transduction pathways |
| PMC10940682__F4 | S-palmitoylation is involved in the regulation of multiple cellular signal transduction pathways |
| PMC10940682__F6 | N-myristoylation is involved in the regulation of multiple cellular signal transduction pathways |
| PMC10940682__F8 | S-prenylation is involved in the regulation of multiple cellular signal transduction pathways |
| PMC10941343__F12 | Elucidating the anti-hypertensive mechanisms of Uncaria rhynchophylla-Alisma plantago-aquatica L: an integrated network pharmacology, cluster analysis, and molecular docking approach |
| PMC10941343__F9 | Elucidating the anti-hypertensive mechanisms of Uncaria rhynchophylla-Alisma plantago-aquatica L: an integrated network pharmacology, cluster analysis, and molecular docking approach |
| PMC10941471__F7 | Graphical abstract |
| PMC10942021__F9 | Crosstalk between mTOR and AMPK |
| PMC10942463__F10 | Nucleotide metabolism associated with purine and pyrimidine pathways |
| PMC10942825__F6 | Signaling pathways of DUSP22 in EndMT |
| PMC10943178__F10 | The effects of EC‐EVs in sepsis‐related ALI/ARDS |
| PMC10943832__F2 | Metabolic pathway of tryptophan (Trp) |
| PMC10943832__F5 | AhR signaling pathway |
| PMC10943956__F2 | SASP regulation of aging intervertebral disc cells converges on the p53/p21 and p16/Rb pathways |
| PMC10944040__F1 | Molecular mechanisms of IL‐1 release |
| PMC10944040__F2 | IL‐1 signaling pathway |
| PMC10944040__F3 | Antagonism of IL‐1 signaling pathway |
| PMC10944225__F8 | Schematic summary of the mechanism of the role of BMP2 and the BMPR/Smad1 signaling pathway in the modulation of CGRP expression and progression of BCP |
| PMC10944245__F10 | Cytotoxic effect of flavonoids resulted from nuclear factor erythroid 2 (Nerf-2), Ak strain transforming (Akt), and nuclear factor kappa B (NFƙB) pathways |
| PMC10944245__F9 | Cytotoxic effect of flavonoids related to MAPK and PI3KAkt pathways |
| PMC10944252__F2 | Enrichment analysis of KEGG signaling pathway, hub gene screening and PPI network analysis based on Genemania database |
| PMC10944288__F1 | chemokine signaling pathway (hsa04062) as outlined in the KEGG database |
| PMC10944957__F1 | TGFB superfamily signaling pathway and the potential therapeutic targets in pancreatic cancer |
| PMC10945197__F1 | Function and mechanism of exosomes derived from different cells as communication mediators in colorectal cancer metastasis |
| PMC10945197__F3 | Function and mechanism of exosomes derived from different cells as communication mediators in colorectal cancer metastasis |
| PMC10945329__F10 | Exosomes generated from human adipose mesenchymal stem cells reduce hepatic fibrosis by suppressing the PI3K/Akt/mTOR signaling pathway and altering choline metabolism |
| PMC10945329__F13 | MSC-EV effect on bone regeneration |
| PMC10945329__F9 | ADSCs-Exo pathway reduces pyroptosis and improves tissue regeneration in the liver, which has been injured by ischemia-reperfusion and partial resection |
| PMC10946266__F6 | MgH2 protects against APAP-AKI by inhibiting TXNIP/NLRP3/NFKB pathway |
| PMC10946270__F3 | Classical and alternative pathways of NF-KB signalling are mediated by a variety of receptors and signalling molecules, including TLR, CD30L, CD40L, RANKL, etc |
| PMC10948231__F2 | PPARG and the PTEN-PI3K/AKT Signaling Axis May Cofunction in Promoting Chemosensitivity in Hypopharyngeal Squamous Cell Carcinoma |
| PMC10948527__F2 | SHP2 signaling pathways: SHP2-dependent signaling in both developing and established cancer cells is illustrated, with arrows denoting positive regulators and T-bars indicating negative regulators |
| PMC10948527__F4 | Immune cell-specific roles of SHP2 |
| PMC10948547__F1 | Molecular mechanisms of TLR4 in osteoporosis development |
| PMC10949532__F1 | Non-canonical NFKB pathway and its regulation: The non-canonical signaling pathway may be initiated through the binding of a variety of exogenous ligands to their cognate receptors (top right) |
| PMC10949534__F10 | KEGG pathway analysis: (A) PI3K-AKT signaling pathway and (B) MAPK signaling pathway |
| PMC10949534__F11 | Integrating network pharmacology with molecular docking to rationalize the ethnomedicinal use of Alchornea laxiflora (Benth.) Pax & K. Hoffm. for efficient treatment of depression |
| PMC10949727__F2 | FOXO3a regulating apoptosis and cell cycle in breast cancer |
| PMC10949727__F3 | FOXO3a regulating EMT and drug resistance in breast cancer |
| PMC10949864__F2 | Cancer-associated alterations of Ca2+ fluxes at acidic tumor microenvironment and targets |
| PMC10949864__F3 | Mechanisms for the extracellular acidification inducing alterations of Ca2+ fluxes |
| PMC10950698__F9 | IL-13 facilitates ferroptotic death in asthmatic epithelial cells via SOCS1-mediated ubiquitinated degradation of SLC7A11 |
| PMC10950852__F9 | Paradigm illustrates the beneficial efficacy of ginseng extracts in modulating circadian rhythm and inflammation |
| PMC10950892__F2 | Shows the benefits of Warburg and molecular signaling |
| PMC10950925__F2 | Visualization of the extrinsic and intrinsic apoptosis pathway |
| PMC10950925__F5 | Ferroptosis Signaling Pathway |
| PMC10950953__F4 | Immune cells interacted with jaw stem cells by signaling pathways |
| PMC10950953__F5 | Cellular interaction of immune cells and stem cells in the jaw |
| PMC10951222__F5 | Tumor evolutionary analysis and clinical vignettes for patients who derived clinical benefit from palbociclib, everolimus, and exemestane triplet therapy |
| PMC10951359__F6 | CGRP-induced anxiety-like behavior through epigenetic regulation of the p-HP1G–KLF11–MAOB–dopamine pathway |
| PMC10951504__F5 | Underlying mechanism of obesity and hyperuricemia |
| PMC10951504__F6 | Associations between obesity and hyperuricemia combing mendelian randomization with network pharmacology |
| PMC10952045__F4 | Various molecular mechanism of the osteogenic and osteoclastogenic function through cellular uptake of GNPs and functionalized GNPs |
| PMC10952836__F1 | Signaling pathways involved in ferroptosis regulation |
| PMC10953212__F1 | Lipid metabolism in NAFLD |
| PMC10953212__F2 | Glucose–insulin signaling pathway |
| PMC10953212__F4 | Relationship between inflammation and NASH disease progression |
| PMC10954797__F2 | Graphical representation of stress signal-mediated dysregulation of p53 expression during progression from colitis to cancer |
| PMC10954797__F4 | ERCC4 may serve as an important regulatory factor for the upregulation of PD-L1 expression induced by DNA damage signals and DDR defects |
| PMC10955039__F6 | Hippo signalling pathway in ferroptosis |
| PMC10955158__F5 | FLRT3 and TGF‐B/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia |
| PMC10956371__F1 | UPR signaling pathway |
| PMC10957538__F1 | Impact of particulate air pollution on airway injury and epithelial plasticity; underlying mechanisms |
| PMC10957538__F2 | Epithelial plasticity and impact of particulate matter (PM): Exposure to PM in short term, leads to inhibition of Notch1 by stimulating STAT3 and aryl hydrocarbon receptor (AhR) activation in basal epithelial cells |
| PMC10957538__F3 | Impact of particulate matter (PM) on airway remodelling |
| PMC10957552__F1 | Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis |
| PMC10957566__F2 | Protective effect of the Notch signaling pathway on B cells under irradiation exposure |
| PMC10957617__F3 | Versatile Mechanisms of STING |
| PMC10957658__F1 | AA metabolism |
| PMC10957658__F3 | COX-2-PGE2 signalling pathway in RCC |
| PMC10957658__F4 | Membrane receptor mechanism of EET in RCC |
| PMC10958678__F6 | Functional activities of mut‐p53 in cancers |
| PMC10958678__F7 | P53 and mut‐p53 in the TME during cancer development |
| PMC10958717__F2 | Oxidized lipids and cholesterol affect MSC differentiation |
| PMC10959754__F4 | Ubiquitination in TNF signaling |
| PMC10960062__F5 | Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity |
| PMC10960062__F6 | Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity |
| PMC10960062__F7 | Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity |
| PMC10960420__F12 | Patterns of effectiveness of C |
| PMC10960729__F2 | Triggers of cGAS–STING signaling pathway |
| PMC10960729__F3 | Signal transduction mechanism of cGAS–STING |
| PMC10960729__F4 | Activation and inhibition of the cGAS–STING signaling pathway in viral infection |
| PMC10960729__F5 | Tumor suppression and promotion of the cGAS–STING signaling pathway |
| PMC10960729__F6 | Activation of cGAS–STING signaling pathway in autoimmune diseases, neurological diseases, and visceral inflammations |
| PMC10960765__F2 | Ubiquitination enzymes in the Wnt/Beta-catenin signaling pathway of CRC |
| PMC10960957__F5 | Ferrihydrite-mediated methanotrophic nitrogen fixation in paddy soil under hypoxia |
| PMC10960969__F8 | Metabolic pathway of methanotrophs |
| PMC10961392__F2 | Recent advances of myotubularin-related (MTMR) protein family in cardiovascular diseases |
| PMC10962118__F9 | Mechanistic map of PELI1 ubiquitination of RPS3 activating the PI3K/AKT/GSK3B signaling pathway, promoting p53 degradation, and thus facilitating progression in PC |
| PMC10962462__F2 | Novel molecular targets in endometrial cancer (EC) |
| PMC10963404__F6 | Mode of action of DMXAA and its derivative HHMX in human and mice |
| PMC10963420__F1 | Mechanism of astrocyte regulation of Lcn-2 |
| PMC10963452__F2 | Schematic plots illustrate the signaling mechanism of various adipokines in intervertebral disc cells |
| PMC10963452__F3 | Schematic plots illustrate the signaling mechanism of various osteokines in intervertebral disc cells |
| PMC10963452__F4 | Schematic plots illustrate the signaling mechanism of other organokines in intervertebral disc cells |
| PMC10963904__F2 | Metabolic map of the l‐methionine synthesis pathway of E |
| PMC10963904__F3 | Metabolic map of the l‐methionine synthesis pathway of E |
| PMC10963904__F4 | Metabolic map of the L‐methionine synthesis pathway of E |
| PMC10963930__F0 | An active form of vitamin D, calcitriol, directly enhances the expression of Rspo2 by binding to the vitamin D receptor (VDR) |
| PMC10964526__F8 | Potential pathways of exercise training to improve pulmonary function |
| PMC10965438__F1 | Nanomaterials modulating TAMs for the treatment of GC |
| PMC10965438__F13 | Nanomaterials modulating TAMs polarization for the treatment of pancreatic cancer |
| PMC10965438__F15 | Macrophage membrane-coated nanomaterials and macrophage-based microrobot for the treatment of digestive system tumor |
| PMC10965438__F6 | Nanomaterials modulating TAM polarization for the treatment of HCC via the STAT signaling pathway |
| PMC10965438__F7 | Nanomaterials modulating TAMs polarization for the treatment of HCC via the NFKB signaling pathway |
| PMC10966134__F8 | Schematic illustrating the proposed mechanism by which the PERK pathway modulates autophagy during RACK1‐mediated neuroprotection after TBI |
| PMC10966608__F4 | EcDNA in drug resistance |
| PMC10967111__F8 | RTEL1/JNK/ELK-1 signaling-induced tumorigenesis of glioma |
| PMC10967197__F10 | The role of the IGF2BP2-TRPM2-AS/PABPC1-NUMB-NOTCH1 axis in GBC angiogenesis |
| PMC10967338__F2 | EGFR wild type and EGFRvIII mutated comparison |
| PMC10967338__F3 | Therapeutic tyrosine kinase inhibitors and anti-EGFR monoclonal antibodies in glioblastoma anti-EGFR mAbs bind the EGFR extracellular domain, preventing EGFR dimerization and subsequent activation |
| PMC10967338__F4 | IL13RA1/IL4RA JAK-STAT6 pathway, IL13RA2, and single-domain vNAR coupled to IL13RA2 |
| PMC10967338__F5 | Allosteric inhibition of Aurora-A kinase by the vNAR-D01 intrabody |
| PMC10967338__F7 | TGFB canonical intracellular pathways and single-domain vNAR T1 coupled to TGFB1 |
| PMC10967382__F5 | Altered sphingolipid metabolism and signaling in monocytes and neutrophils during pneumonia |
| PMC10967436__F7 | ROS modulation of the Keap1-Nrf2-ARE signaling pathway |
| PMC10967781__F1 | Functional connections between the IR and IGF-R signaling axis |
| PMC10967781__F2 | Insulin-like Growth Factor-1 Receptor in Tobacco Smoking-Associated Lung Cancer Development |
| PMC10967848__F1 | Representation of metabolic pathways of lipoprotein |
| PMC10968029__F1 | Illustration of GRB2 in humans and other organisms, highlighting its role in signal transduction and depicting the subcellular localization of GRB2 |
| PMC10968029__F3 | Diagrammatic portrayal of GRB2 splicing variants, particularly GRB3-3, in signal transduction |
| PMC10968029__F4 | Configuration of GRB2 in Protein Interaction and Signal Transduction |
| PMC10968114__F6 | TSG-6 Inhibits the NFKB Signaling Pathway and Promotes the Odontogenic Differentiation of Dental Pulp Stem Cells via CD44 in an Inflammatory Environment |
| PMC10968131__F5 | EFNA4, FGFR4, SLC3A2, and HNF1A are involved in signaling pathways that may promote carcinogenesis |
| PMC10968226__F2 | TRPV4 channels in osteoarthritis |
| PMC10968558__F2 | Mitochondrial dysfunction in the pathogenesis of SCA3 |
| PMC10968558__F3 | Alteration of DNA damage response in the pathogenesis of SCA3 |
| PMC10968558__F6 | Oxidative Stress in Spinocerebellar Ataxia Type 3 and Its Attenuation by Herbal Remedies in Traditional Chinese Medicine: A Systematic Review |
| PMC10968822__F3 | Upregulation and downregulation of PD-L1 by YY1 through various factors |
| PMC10968836__F2 | Comparison of the signalling pathways triggered by TNFR1, Fas and TRAIL agonist receptors |
| PMC10968836__F3 | TRAIL canonical signalling pro-apoptotic pathway |
| PMC10968836__F4 | DR5 non-apoptotic signalling pathways |
| PMC10968836__F5 | TRAIL-induced non-canonical pro-tumoral signalling via DR5 secondary complex formation |
| PMC10969083__F4 | Regulated genes in the Adrenergic signaling in cardiomyocyte KEGG-constructed pathway |
| PMC10969083__F5 | Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways |
| PMC10969083__F6 | Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways |
| PMC10969083__F7 | Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways |
| PMC10969160__F1 | Summary of potential therapeutic targets |
| PMC10970066__F1 | Major components and auxiliary factors of the Notch signaling pathway (modified from ) |
| PMC10970097__F1 | The PI3K/Akt/mTOR signaling pathway |
| PMC10970167__F1 | The protein interactome of PDE4A, B, C and D with their interconnecting protein neighbors |
| PMC10970237__F5 | Zein-Derived Peptides from Corn Promote the Proliferation of C2C12 Myoblasts via Crosstalk of mTORC1 and mTORC2 Signaling Pathways |
| PMC10970282__F8 | Construction of the potential miRNA-target negative correlation regulatory network involved in the FoxO signaling pathway following G |
| PMC10970410__F12 | LncRNAs potentially involved in the immaturity-stemness regulation processes in the human keratinocyte lineage |
| PMC10970410__F8 | Transcriptional Regulatory Networks (TRNs) based on DE pcRNAs common to KLF4KD and MXD4KD cells, in association with lncRNAs |
| PMC10970480__F2 | Lipid metabolism-related proteins and pathways involving mitochondria-associated membranes |
| PMC10970480__F3 | Potential mechanisms by which exercise intervenes in insulin resistance through mitochondria-associated membranes |
| PMC10970955__F1 | Systematic engineering for the de novo biosynthesis of genistein and glycosylated derivatives |
| PMC10971110__F3 | Immune response and gene expression through the NF-kB signaling pathway in sepsis |
| PMC10971231__F1 | Interplay of signaling pathways: cellular dynamics within the pancreatic ductal adenocarcinoma microenvironment |
| PMC10971231__F2 | Pivotal role of the NGF/TrkA signaling pathway in PDAC |
| PMC10971254__F10 | Binding of IL-33 to its receptor induces the MyD88/IRAK1/IRAK4/TRAF6/NFKB- dependent signaling pathway and the TRAF6/MAPK/AP-1-dependent signaling pathway |
| PMC10971254__F8 | Binding of IL-25 to its receptor induces the transcription of IL-25 responsive genes via the TRAF6/NFKB-dependent signaling cascade and TRAF4/MAPK/AP-1-dependent signaling pathway |
| PMC10971338__F1 | General schemes of the NAD+ metabolic pathway |
| PMC10971967__F6 | Proteomics analysis of gastrocnemius and soleus muscle in the ET group |
| PMC10973144__F2 | Protein glycosylation is closely interconnected with glycolysis and other metabolic pathways |
| PMC10973144__F3 | Pathological macrophages that promote inflammation or fibrosis have altered metabolism as a results of lung injury |
| PMC10973673__F1 | Crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy |
| PMC10974036__F12 | Recent Advances in the Nutritional Value, Chemical Compositions, Pharmacological Activity, and Application Value of Orychophragmus violaceus: A Comprehensive Review |
| PMC10974426__F1 | Virus-activated intracellular signaling pathways |
| PMC10975175__F2 | Heat stress triggers nitric oxide (NO) production and increases calcium levels |
| PMC10975212__F1 | TGFB/SMAD signaling pathway |
| PMC10975212__F5 | Non-SMAD, non-canonical TGFB pathways |
| PMC10975235__F2 | Type I IFN signaling |
| PMC10975298__F1 | Mechanisms of drug resistance in cancer cells |
| PMC10975298__F4 | Signaling pathways against resistant cancer |
| PMC10975450__F2 | Signaling pathway molecular mechanisms: Several signaling pathways play a major role in tissue development and thus in PSC differentiation, specifically into cardiac tissue |
| PMC10975841__F4 | Dietary Factors on DNA Methylation Levels of TNF-Alpha Gene and Proteome Profiles in Obese Men |
| PMC10975890__F1 | MAPK signaling pathway (KEGG: 04010) enriched in bovine fibroblasts infected with B |
| PMC10976354__F2 | KEGG enrichment analysis of the SGNI targets |
| PMC10976388__S1 | Depiction of Wnt Signaling Dysregulation in TNBC Cells When Compared to Healthy, Noncancerous Cells |
| PMC10976710__F4 | Molecular connection between the mTOR signaling pathway and polyploid giant cancer cells: (A)xa0The interplay between polyploidy, senescence and mTOR signaling |
| PMC10976794__F2 | Schematic overview of the Hippo signaling pathway |
| PMC10976794__F3 | Schematic overview of LMNA mutant pathways and MAPK3/1 (ERK1/2) initiated changes in cardiac remodeling |
| PMC10976824__F2 | Infection of endothelial cells by pathogenic microorganisms triggers the activation of the NFKB pathway, resulting in increased levels of HIF-1A |
| PMC10977403__F2 | Dependence receptors have two properties: when the ligand is present, binding to the ligand promotes cell survival, migration or differentiation |
| PMC10977553__F6 | Mechanism through which agarwood against RAS |
| PMC10977574__F7 | Core pathway of AP intervened by SHG (PI3K-Akt signaling pathway) |
| PMC10977574__F8 | Compound-key target-core pathway |
| PMC10977574__F9 | Core-compound-core key target-core pathway |
| PMC10978726__F3 | SKP2-p27 axis |
| PMC10978726__F4 | Involvement of SKP2 in hematological malignanices |
| PMC10978763__F3 | Polyphenols and immunomodulation: a mitochondria-centered multi-modal approach |
| PMC10979123__F7 | Schematic diagram illustrates the multifaceted role of the redox-sensitive GSK3B in podocyte injury upon type 2 diabetic insult and the protective effect of targeting GSK3B |
| PMC10979625__F8 | Brief figure summarizes the FGF2-FGFR1-p21 regulatory pathway in FGFR1 amplified ERu2009+u2009BC cells |
| PMC10979751__F3 | Macrophages in osteosarcoma cell proliferation and metastasis |
| PMC10980228__F6 | H. Model for the BCM mode of action |
| PMC10980521__F7 | Main pathways of reproductive candidate genes for follicular growth and ovulation in Tibetan sheep |
| PMC10981134__F1 | Main alterations in TCR signaling pathway and accessory molecules associated with autoimmunity/immunodeficiency |
| PMC10981339__F3 | Anti-inflammatory effects of SIRT in IVDD |
| PMC10981749__F8 | Model for the induction of proinflammatory SASP by typhoid toxin |
| PMC10981756__F7 | Mechanism of the antineoplastic role of PQR309 and gemcitabine in nasopharyngeal carcinoma |
| PMC10982327__F2 | Molecular pathways involved in animal glaucoma models at the level of retinal ganglion cell |
| PMC10982379__F1 | Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer |
| PMC10982379__F2 | Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer |
| PMC10982379__F3 | Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer |
| PMC10982379__F4 | Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer |
| PMC10982379__F5 | Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer |
| PMC10982379__F6 | Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer |
| PMC10982391__F1 | Direct immunomodulatory function of TDEs on CD8+ T cells |
| PMC10982391__F2 | TDEs indirectly regulate CD8+ T cells via the TME cells |
| PMC10982457__F1 | Viral RNA‐driven peripheral serotonin reduction impairs neurocognition by directly dampening vagal signaling |
| PMC10982647__F8 | Metabolic rewiring mechanisms in drug-resistant breast cancer cells |
| PMC10982685__F1 | Integration of Psat1 into glycolysis and the serine biosynthetic pathway and its contribution to additional signaling mechanisms |
| PMC10983073__F3 | Diagram of the inhibition of TSLP Signaling by HZ-1127 and TEZE |
| PMC10984535__F6 | Pathway dynamics of islets during diabetes progression |
| PMC10984988__F9 | Insights from bioinformatics analysis reveal that lipopolysaccharide induces activation of chemokine-related signaling pathways in human nasal epithelial cells |
| PMC10985004__F5 | Construction of signaling pathway between DEPs |
| PMC10985007__F1 | HIFs and NRF2, adaptive response systems to variable oxygen availability |
| PMC10985098__F3 | Skeletal interoception in the aberrant subchondral bone remodeling of OA |
| PMC10985190__F2 | Nerves promote tumour cell growth and survival The neural impact on tumors is mediated through sympathetic, parasympathetic, and sensory nerves, as indicated by solid lines in the diagram |
| PMC10985190__F4 | Communication between tumor cells and nerves facilitates tumor perineural invasion |
| PMC10985261__F12 | The VDR-mTOR Signaling Pathway in DKD Development |
| PMC10985914__F2 | Endogenous estrogen metabolites as oxidative stress mediators and endometrial cancer biomarkers |
| PMC10985960__F10 | Hypothesis of possible IFN-I signaling pathway regulatory mechanism based on our findings in PD |
| PMC10985998__F8 | Expression of genes in carbon, ATP, NADPH metabolism in C |
| PMC10986035__F5 | Pattern diagram for the role of NCAPD3 in NSCLC cell proliferation and apoptosis |
| PMC10986082__F1 | Targeting TFs in CSC from multiple perspectives Axa0Directly blocking the combination of TFs and DNA: mainly through epigenetic mechanisms |
| PMC10986082__F2 | Multiple mechanisms of environmental stress regulating CSC transcription Axa0The immune cells in TME activate the STAT, Wnt, AKT and Notch pathway of CSC by mainly releasing cytokines (IL-6) and inducing contact |
| PMC10987301__F3 | visually outlines the RAS/microRNAs (miRNAs) pathway in cancer metastasis, emphasizing the pivotal role of the Ras signaling pathway, particularly in tumor initiation and metastasis |
| PMC10987302__F1 | Crosstalk between lncRNAs and Wnt/Beta-catenin signaling pathways in lung cancers: From cancer progression to therapeutic response |
| PMC10987323__F10 | MtETC in M2 macrophage polarization |
| PMC10987323__F7 | MtETC in regulating bacterial infection |
| PMC10987323__F9 | MtETC in M1 macrophage polarization |
| PMC10987652__F7 | GSK3B inhibition inhibits microtubule dynamics |
| PMC10987721__F2 | Akkermansia muciniphila: a potential candidate for ameliorating metabolic diseases |
| PMC10987773__F3 | Hepatic glucose metabolic pathway during pregnancy |
| PMC10987773__F4 | Hepatic lipid metabolic pathway during pregnancy |
| PMC10987773__F5 | Hepatic protein and amino acid metabolic pathway during pregnancy |
| PMC10987845__F1 | Glycan biosynthesis mutants were screened for immune stimulatory properties |
| PMC10989355__F1 | Pivotal signaling cascades in peripheral nerve regeneration (PNR) |
| PMC10989355__F2 | Regulatory signaling pathways activating Schwann cells (SCs) response in peripheral nerve regeneration (PNR) |
| PMC10989355__F4 | Molecular signaling pathways affected by electrical stimulation (ES) of peripheral nerves |
| PMC10989365__F6 | CALD1 facilitates epithelial-mesenchymal transition progression in gastric cancer cells by modulating the PI3K-Akt pathway |
| PMC10990278__F1 | The Wnt signaling pathway |
| PMC10990754__F1 | Various intracellular signaling molecules and pathways involved in HSCR |
| PMC10990754__F3 | NcRNAs related to cell apoptosis, proliferation, migration, and differentiation in HSCR |
| PMC10990851__F8 | Metabolic pathway map of biosynthesis related to photosynthesis |
| PMC10990851__F9 | Integrated transcriptomic and metabolomic analysis reveals the regulation mechanism of early bolting and flowering in two cultivars of Angelica sinensis |
| PMC10991369__F6 | Comparative transcriptome analysis of Trichoderma reesei reveals different gene regulatory networks induced by synthetic mixtures of glucose and Beta-disaccharide |
| PMC10991391__F2 | Integrin receptors influence cellular metabolism through ECM sensing |
| PMC10991391__F3 | TGFB influences cellular metabolism through canonical and non-canonical pathways |
| PMC10991391__F5 | Cellular metabolism and myofibroblast contraction cascades |
| PMC10991915__F4 | Physiological and transcriptome analysis elucidates the metabolic mechanism of versatile Porphyridium purpureum under nitrogen deprivation for exopolysaccharides accumulation |
| PMC10991944__F1 | Metabolic engineering of methylotrophic Pichia pastoris for the production of Beta-alanine |
| PMC10992393__F1 | De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica |
| PMC10992410__F2 | Metabolic engineering strategies for de novo biosynthesis of sterols and steroids in yeast |
| PMC10992626__F2 | Simplified illustration showing key pathways involved in disc degeneration |
| PMC10993167__F2 | Related regulators of N6‐methyladenosine (m6A), 5‐methylcytosine (m5C) and N7‐methylguanosine (m7G) are involved in the signalling pathways of drug resistance during tumour treatment |
| PMC10993167__F5 | Molecular mechanism of action of the FTO inhibitor 18097 |
| PMC10993167__F6 | FTO, ALKBH5 and pseudouridine synthase partial inhibitors and their inhibitory pathways are introduced |
| PMC10993426__F1 | Metabolites, metabolic pathways and related metabolic genes that play the roles in apoptosis |
| PMC10993426__F2 | Metabolites, metabolic pathways and related metabolic genes that take part in necrosis and necroptosis |
| PMC10993426__F3 | Metabolites, metabolic pathways and related metabolic genes that play the roles in ferroptosis |
| PMC10993426__F4 | Metabolites, metabolic pathways and related metabolic genes that play the roles in pyroptosis |
| PMC10993426__F7 | Metabolites, metabolic pathways and related metabolic genes that work in autophagy |
| PMC10993482__F4 | Gal-1- and Gal-3 pathways promoting EMT in fibrosis |
| PMC10993482__F5 | Gal-1 pathways promoting EMT in cancer |
| PMC10993482__F6 | Gal-3, Gal-4 and Gal-8 pathways to EMT in cancer |
| PMC10993494__F9 | Extracellular vesicles-coupled miRNAs from oviduct and uterus modulate signaling pathways related to lipid metabolism and bovine early embryo development |
| PMC10994423__F5 | Advances in the application of traditional Chinese medicine during the COVID-19 recovery period: A review |
| PMC10995224__F2 | Signaling pathway that was affected by ridaforolimus |
| PMC10995332__F2 | Underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma |
| PMC10995332__F3 | Underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma |
| PMC10995332__F4 | MiRNAs affect the occurrence and development of EMT in liver cancer cells by activating the TGFB signaling pathway and cross-talking multiple signaling pathways including PI3 K and MAPK |
| PMC10995332__F5 | Underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma |
| PMC10995750__F3 | Genes enriched in plasma membrane estrogen receptor signalling pathway |
| PMC10995981__F2 | CircRNAs play a pivotal role in the advancement of esophageal cancer by modulating the Wnt pathway through diverse mechanisms |
| PMC10995981__F3 | circRNAs play a pivotal role in the initiation and progression of liver cancer by regulating the Wnt pathway through diverse mechanisms |
| PMC10996061__F2 | Impact of amotosalen/UVA treatment on phosphoproteome signaling and platelet pathways |
| PMC10996135__F6 | Distribution of common targets in the two most associated pathways |
| PMC10996278__F5 | Major TCR signalling pathways |
| PMC10996278__F6 | Critical genes and signalling pathways engage in T cell anti-tumour responses |
| PMC10998350__F5 | Pyrroloquinoline quinone promotes human mesenchymal stem cell-derived mitochondria to improve premature ovarian insufficiency in mice through the SIRT1/ATM/p53 pathway |
| PMC10999050__F3 | Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis |
| PMC10999489__F2 | Personalized treatment concepts in extraocular cancer |
| PMC10999569__F3 | PIAS family in cancer: from basic mechanisms to clinical applications |
| PMC10999658__F7 | Molecular mechanism underlying CE accumulation in ccRCC and suppression of cancer progression upon CE depletion |
| PMC11000312__F1 | Mechanisms underlying SALL4 regulation and function in esophageal cancer |
| PMC11000312__F2 | Mechanisms underlying SALL4 regulation and function in gastric cancer |
| PMC11000312__F3 | Mechanisms underlying SALL4 regulation and function in colorectal cancer |
| PMC11000312__F4 | Mechanisms underlying SALL4 regulation and function in liver cancer |
| PMC11000535__F3 | STAT3, EMT-TFs, miRNAs and lncRNAs form complex network to regulate EMT |
| PMC11001198__F5 | Age-related changes after intracerebral hemorrhage: a comparative proteomics analysis of perihematomal tissue |
| PMC11001198__F6 | Age-related changes after intracerebral hemorrhage: a comparative proteomics analysis of perihematomal tissue |
| PMC11002130__F4 | tsRNAs as inhibitors of MAPK pathway activation via targeting MAPK-related proteins |
| PMC11002443__F6 | Putrescine Upregulates Melanogenesis Through Modulation of MITF Transcription Factor in B16F1 Mouse Melanoma Cells |
| PMC11002873__F3 | Working model for the Wnt, TGFB, and Pax6 signalling in the regulation of ciliary body development |
| PMC11002909__F2 | Antiviral role of ubiquitination in enterovirus infection |
| PMC11003173__F10 | Hypothetical modules and cold response pathways of eggplant |
| PMC11003173__F5 | Metabolic pathways of glutathione and expression profile of related genes |
| PMC11003275__F1 | Schematic chart for molecular mechanisms of metabolic dysregulation in DCM |
| PMC11003747__SF3_1 | I-ASD p-proteome network analysis |
| PMC11003747__SF3_2 | I6pDel p-proteome network analysis |
| PMC11003748__F1 | Matrix-derived coupling factors |
| PMC11003748__F2 | Clastokines produced by osteoclasts and osteoclast precursors and interaction with their receptors on cells from the osteoblast lineage |
| PMC11003766__F5 | The BTN2A1-BTN3A1-BTN3A2 complex regulation |
| PMC11003951__F8 | Inflammatory Factor IL1A Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca2+/CaMK2b Pathway |
| PMC11003953__F2 | Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic |
| PMC11003953__F3 | Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic |
| PMC11004224__F5 | PM2.5, component cause of severe metabolically abnormal obesity: An in silico, observational and analytical study |
| PMC11004224__F7 | PM2.5, component cause of severe metabolically abnormal obesity: An in silico, observational and analytical study |
| PMC11004224__F8 | KEGG network diagram of cytokine-cytokine receptor interactionLarge white box: biological pathway map |
| PMC11004261__F3 | Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions |
| PMC11004261__F4 | Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions |
| PMC11004261__F5 | Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions |
| PMC11004450__F1 | Single cell and bulk RNA expression analyses identify enhanced hexosamine biosynthetic pathway and O-GlcNAcylation in acute myeloid leukemia blasts and stem cells |
| PMC11004450__F6 | Single cell and bulk RNA expression analyses identify enhanced hexosamine biosynthetic pathway and O-GlcNAcylation in acute myeloid leukemia blasts and stem cells |
| PMC11004819__F3 | Pharmacogenomics-based systematic review of coronary artery disease based on personalized medicine procedure |
| PMC11004986__F8 | Autotaxin and lysophosphatidic acid deficiencies on depression-like behaviors in mice exposed to chronic unpredictable mild stress |
| PMC11005058__F2 | Adipocyte leptin promotes lymphocyte activation and TH17 differentiation |
| PMC11005242__F7 | GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathway |
| PMC11005288__F5 | Compound Shenma Jingfu granule alleviates cerebral ischemia via HIF-1Alpha-mediated promotion of angiogenesis |
| PMC11005695__S1 | Thermosensitive Bi‐Adjuvant Hydrogel Triggers Epitope Spreading to Promote the Anti‐Tumor Efficacy of Frameshift Neoantigens |
| PMC11005958__F1 | Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo |
| PMC11006178__F12 | Proposed schematic model of METTL14 in TLR4-mediated innate immunity and promoting CSFV replication |
| PMC11006482__F9 | Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice |
| PMC11006730__F4 | Acid-sensing ion channels and downstream signalling in cancer cells: is there a mechanistic link? |
| PMC11006979__F2 | Unveiling the impact of CDK8 on tumor progression: mechanisms and therapeutic strategies |
| PMC11007064__F6 | Enhanced GATA4 expression in senescent systemic lupus erythematosus monocytes promotes high levels of IFNA production |
| PMC11007101__F2 | Therapeutic prospects of nectin-4 in cancer: applications and value |
| PMC11007187__F1 | Decoding the secrets of longevity: unraveling nutraceutical and miRNA-Mediated aging pathways and therapeutic strategies |
| PMC11007187__F4 | Decoding the secrets of longevity: unraveling nutraceutical and miRNA-Mediated aging pathways and therapeutic strategies |
| PMC11007890__F5 | Polycomb repressive complex 2 and its core component EZH2: potential targeted therapeutic strategies for head and neck squamous cell carcinoma |
| PMC11008418__F8 | Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis |
| PMC11008420__F1 | MicroRNAs: A novel signature in the metastasis of esophageal squamous cell carcinoma |
| PMC11008420__F2 | MicroRNAs: A novel signature in the metastasis of esophageal squamous cell carcinoma |
| PMC11008464__F1 | New insight into arginine and tryptophan metabolism in macrophage activation during tuberculosis |
| PMC11008728__F2 | Fine-tuning tumor- and allo-immunity: advances in the use of immune checkpoint inhibitors in kidney transplant recipients |
| PMC11009036__F1 | Nonsense-mediated RNA decay pathway |
| PMC11009184__F7 | Translatability of mouse muscle-aging for humans: the role of sex |
| PMC11009220__F2 | Interplay of aging, adipose tissue, and COVID-19: a potent alliance with implications for health |
| PMC11009445__F1 | Emerging role of lncRNAs as mechanical signaling molecules in mechanotransduction and their association with Hippo-YAP signaling: a review |
| PMC11010095__F8 | The pivotal role of CTRP9 in reendothelialization of EPCs and the protective mechanisms of AMPK‐mediated Akt/eNOS signaling involved in adipoR1 and N‐cadherin receptor |
| PMC11010261__F1 | YAP/TAZ‐TEAD signalling axis: A new therapeutic target in malignant pleural mesothelioma |
| PMC11010636__F2 | Exploring the regulatory mechanism of intestinal flora based on PD-1 receptor/ligand targeted cancer immunotherapy |
| PMC11010822__F7 | MTA1/mTOR pathway in prostate cancer |
| PMC11011033__F3 | NDRGs in Breast Cancer: A Review and In Silico Analysis |
| PMC11011055__F7 | Targeting Siglec–Sialylated MUC1 Immune Axis in Cancer |
| PMC11011165__F1 | Inappropriate STAT activation in cancer cells |
| PMC11011199__F2 | Prediction of Response to Anti-Angiogenic Treatment for Advanced Colorectal Cancer Patients: From Biological Factors to Functional Imaging |
| PMC11011352__F1 | Regulating Protein–RNA Interactions: Advances in Targeting the LIN28/Let-7 Pathway |
| PMC11011407__F2 | Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies |
| PMC11011407__F3 | Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies |
| PMC11011407__F4 | Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies |
| PMC11011430__F5 | Signaling pathways upregulated in higher Gleason grade groups |
| PMC11011430__F6 | Analysis of the Gene Networks and Pathways Correlated with Tissue Differentiation in Prostate Cancer |
| PMC11011519__F2 | NFKB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury |
| PMC11011684__F3 | Gene Expression Patterns Associated with Survival in Glioblastoma |
| PMC11011857__F3 | Genetic Signature of Human Pancreatic Cancer and Personalized Targeting |
| PMC11011897__F3 | Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature |
| PMC11011983__F1 | Alterations in Proteostasis Mechanisms in Niemann–Pick Type C Disease |
| PMC11012077__F2 | Chemokine Fractalkine and Non-Obstructive Coronary Artery Disease—Is There a Link? |
| PMC11012138__F3 | Oxygen sensing and HIF pathway activation in embryonic neurogenesis |
| PMC11012149__F2 | Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease |
| PMC11012151__F2 | Exercise in Diabetic Nephropathy: Protective Effects and Molecular Mechanism |
| PMC11012151__F7 | Exercise in Diabetic Nephropathy: Protective Effects and Molecular Mechanism |
| PMC11012155__F1 | Endocrine Disruption Chemical-Regulated Aryl Hydrocarbon Receptor Activity in the Pathogenesis of Pancreatic Diseases and Cancer |
| PMC11012292__F1 | Epigenetics, Nutrition, and the Brain: Improving Mental Health through Diet |
| PMC11012314__F7 | Boosting Clear Cell Renal Carcinoma-Specific Drug Discovery Using a Deep Learning Algorithm and Single-Cell Analysis |
| PMC11012409__F1 | Agnostic Administration of Targeted Anticancer Drugs: Looking for a Balance between Hype and Caution |
| PMC11012486__F1 | Identification of PTPN12 Phosphatase as a Novel Negative Regulator of Hippo Pathway Effectors YAP/TAZ in Breast Cancer |
| PMC11012558__F3 | Calcium and Neural Stem Cell Proliferation |
| PMC11012558__F4 | TRPVs and neural stem cell proliferation |
| PMC11012558__F6 | RTK pathways |
| PMC11012607__F4 | Understanding the Impact of Polyunsaturated Fatty Acids on Age-Related Macular Degeneration: A Review |
| PMC11012648__F1 | Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways |
| PMC11012648__F3 | Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways |
| PMC11012680__F2 | Synthetic Routes and Clinical Application of Representative Small-Molecule EGFR Inhibitors for Cancer Therapy |
| PMC11012756__F5 | Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer |
| PMC11012798__F2 | C and N metabolisms affected by N sources |
| PMC11013124__F1 | Neuroinflammation of Microglial Regulation in Alzheimer’s Disease: Therapeutic Approaches |
| PMC11013310__F6 | Our results are summarized in this diagram |
| PMC11013731__F6 | Sea Cucumber and Blueberry Extracts Suppress Inflammation and Reduce Acute Lung Injury through the Regulation of NFKB/MAPK/JNK Signaling Pathway in Lipopolysaccharide-Treated C57BL/6 Mice |
| PMC11014460__F1 | Responses of HIFs to hypoxia or hyperoxia |
| PMC11014885__F4 | Endosymbiont Tremblaya phenacola influences the reproduction of cotton mealybugs by regulating the mechanistic target of rapamycin pathway |
| PMC11015223__F9 | OMA1 competitively binds to HSPA9 to promote mitophagy and activate the cGAS–STING pathway to mediate GBM immune escape |
| PMC11015399__F1 | Hippo signalling pathway and its impact on eye diseases |
| PMC11015457__F9 | Compound-target-pathway network |
| PMC11015576__F8 | PREX2 contributes to radiation resistance by inhibiting radiotherapy-induced tumor immunogenicity via cGAS/STING/IFNs pathway in colorectal cancer |
| PMC11015656__F1 | Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review |
| PMC11015656__F2 | 20S proteasome inhibitors and their targets |
| PMC11015710__F2 | Rosacea: Pathogenesis and Therapeutic Correlates |
| PMC11015775__F1 | Treatment algorithms of relapsing multiple sclerosis: an exploration based on the available disease-modifying therapies in China |
| PMC11015925__F4 | Circulating Levels of HOTAIR- lncRNA Are Associated with Disease Progression and Clinical Parameters in Type 2 Diabetes Patients |
| PMC11016009__F4 | B7-H3 at the crossroads between tumor plasticity and colorectal cancer progression: a potential target for therapeutic intervention |
| PMC11016017__F3 | Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling |
| PMC11016256__F1 | Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis |
| PMC11016256__F2 | Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis |
| PMC11016256__F3 | Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis |
| PMC11016256__F4 | Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis |
| PMC11016262__F2 | Intestinal Mucosal Immune Barrier: A Powerful Firewall Against Severe Acute Pancreatitis-Associated Acute Lung Injury via the Gut-Lung Axis |
| PMC11016262__F3 | Immune cells along the gut-lung axis |
| PMC11016524__F2 | Understanding PI3K/Akt/mTOR signaling in squamous cell carcinoma: mutated PIK3CA as an example |
| PMC11016731__F2 | Mechanism of tumor cell genesis induced by hypoxia inducible factor (HIF) |
| PMC11016731__F3 | Rationale for immune checkpoint inhibitors plus targeted therapy for advanced renal cell carcinoma |
| PMC11016796__F2 | Proteomic analyses on chicken breast meat with white striping myopathy |
| PMC11016919__F1 | Trimetazidine May Potentially Confer Neuroprotective Effects against COVID-19-Induced Neurological Sequelae via Inhibition of Death-Associated Protein Kinase 1 (DAPK1) Signaling Pathways: An Evidenced-Based Hypothesis |
| PMC11017435__F1 | NcRNAs: A synergistically antiapoptosis therapeutic tool in Alzheimer's disease |
| PMC11018134__F7 | FBL Promotes LPS-Induced Neuroinflammation by Activating the NFKB Signaling Pathway |
| PMC11018843__F1 | Main cytosolic DNA sensors and their downstream pathways |
| PMC11018843__F2 | Alzheimer’s disease (AD) and cytosolic DNA sensors |
| PMC11018843__F3 | Parkinson’s disease (PD) and cytosolic DNA sensors |
| PMC11018843__F4 | Amyotrophic Lateral Sclerosis (ALS) and cytosolic DNA sensors |
| PMC11018997__F6 | Multiple functions of the nonstructural protein 3D in picornavirus infection |
| PMC11019011__F3 | Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity |
| PMC11019011__F4 | Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity |
| PMC11019011__F5 | Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity |
| PMC11019011__F6 | Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity |
| PMC11019012__F2 | Natural products targeting autophagy and apoptosis in NSCLC: a novel therapeutic strategy |
| PMC11019147__F1 | Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging |
| PMC11019147__F3 | Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging |
| PMC11019147__F4 | Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging |
| PMC11019464__F2 | Chemoprophylaxis of precancerous lesions in patients who are at a high risk of developing colorectal cancer (Review) |
| PMC11019495__F3 | Recent advances of nanoparticles on bone tissue engineering and bone cells |
| PMC11019510__F5 | Role and mechanism of TXNDC5 in disease progression |
| PMC11019597__F3 | Heterologous fibrin biopolymer as an emerging approach to peripheral nerve repair: a scoping review |
| PMC11019653__F7 | Effect of 23‑hydroxybetulinic acid on lung adenocarcinoma and its mechanism of action |
| PMC11019658__F1 | Mechanistically, DHM inhibits tumour cell proliferation |
| PMC11019658__F2 | DHM induces apoptosis in tumour cells and induces the associated signalling pathway |
| PMC11019658__F3 | Mechanisms by which DHM inhibits tumour cell invasion and metastasis |
| PMC11019719__F2 | Exercise induction at expression immediate early gene (c-Fos, ARC, EGR-1) in the hippocampus: a systematic review |
| PMC11019826__F8 | Utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction–associated steatohepatitis |
| PMC11019835__F1 | Canonical and non-canonical function of CD55 |
| PMC11020452__F4 | Regulatory mechanism of tsRNAs in cancers |
| PMC11020458__F4 | Direct osteogenic effects and mechanisms of RE NMs |
| PMC11021402__F5 | Fe and S binding by ISCU2 at consecutive stages of de novo [2Fe-2S] cluster biosynthesis |
| PMC11021430__F5 | Representative scheme illustrating regulatory mechanisms of PTEN in BMSCs |
| PMC11021430__F6 | Representative scheme illustrating regulatory mechanisms of PTEN in RPCs |
| PMC11021430__F7 | Representative scheme illustrating regulatory mechanisms of PTEN in HSCFs, SCs, ISCs and SSCs |
| PMC11021710__F3 | Cell cycle signaling pathway (A) and cellular senescence (B) |
| PMC11022384__F3 | Metabolic characteristics of microglia |
| PMC11022384__F4 | Metabolic interactions between tumor cells and GAMs |
| PMC11022384__F5 | Therapeutic strategies targeting metabolism between GAMs and Gliomas |
| PMC11022503__F8 | Proposed mechanism of erroneous differentiation of TSPCs under high glucose |
| PMC11022604__F1 | Wnt/Beta-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic target |
| PMC11023816__F1 | Vitamin A metabolic pathway and the enzymes involved in retinoid metabolic flux in human liver |
| PMC11023816__F9 | Proposed pathways by which paracrine and autocrine cytokine signaling modulates vitamin A metabolism across stellate cell activation phenotypes |
| PMC11023972__F1 | DNA-damage response pathways |
| PMC11023972__F2 | DDR components regulate IFNs signaling pathways |
| PMC11023972__F3 | DDR components regulate cytosolic RNA sensors-dependent IFNs and NFKB signaling pathways |
| PMC11023972__F4 | DDR components regulate NFKB signaling pathways |
| PMC11023972__F5 | DDR components regulate JAK-STAT signaling pathways |
| PMC11024162__F9 | TGFB signaling pathway |
| PMC11024251__F2 | Signaling pathway of EGF |
| PMC11024365__F9 | Proposed modeling of antioxidant mechanisms in H |
| PMC11024688__F4 | Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway of the PI3K-AKT (A, B) and mitogen-activated protein kinase (MAPK) (C, D) signaling pathway was mapped by fold changes |
| PMC11024860__F9 | Working Model: HDAC6 maintains primordial follicle dormancy |
| PMC11025274__F2 | Mechanisms by which the gut microbiota promotes CRC metastasis by targeting seeds |
| PMC11027102__F3 | Blockade of the CD47-SIRPA signaling pathway initiates an adaptive immune response to kill tumor cells |
| PMC11027554__F2 | "hit and run" mechanism posits a potential role for H |
| PMC11028018__F5 | Proposed model illustrating the inhibitory effects of GBE on TGFB downstream signaling pathways |
| PMC11029991__F7 | Bioinformatics-based discovery of biomarkers and immunoinflammatory targets in children with cerebral palsy: An observational study |
| PMC11032202__F3 | Oncogenes versus tumour suppressor genes in glioblastoma |
| PMC11032202__F6 | Intratumoural heterogeneity informs intertumoural heterogeneity |
| PMC11032739__F7 | Musashi2 affecting radiosensitivity of lung cancer by modulating DNA damage repair |
| PMC11033207__F1 | Redox signaling and skeletal muscle adaptation during aerobic exercise |
| PMC11033207__F10 | Redox signaling and skeletal muscle adaptation during aerobic exercise |
| PMC11033207__F6 | Redox signaling and skeletal muscle adaptation during aerobic exercise |
| PMC11033252__F5 | Mechanisms of human NLRP3 inflammasome activation and regulation |
| PMC11033252__F6 | Mechanisms of human NLRP6 inflammasome activation |
| PMC11033278__F8 | PPI interaction network |
| PMC11033413__F2 | Progress of medicinal plants and their active metabolites in ischemia-reperfusion injury of stroke: a novel therapeutic strategy based on regulation of crosstalk between mitophagy and ferroptosis |
| PMC11033433__F2 | Research progress on radiation resistance of cervical cancer |
| PMC11033433__F4 | Research progress on radiation resistance of cervical cancer |
| PMC11033433__F6 | Research progress on radiation resistance of cervical cancer |
| PMC11033433__F7 | Non-coding RNAs involved in the regulation of radiation tolerance in cervical cancer (A) the relationship between lncRNAs and radiotherapy resistance in cervical cancer |
| PMC11033467__F5 | Immunomodulatory effects of a probiotic combination treatment to improve the survival of Pacific oyster (Crassostrea gigas) larvae against infection by Vibrio coralliilyticus |
| PMC11033503__F1 | C/EBPB regulates signaling pathways associated with brain inflammation in AD |
| PMC11033503__F2 | C/EBPB: A transcription factor associated with the irreversible progression of Alzheimer's disease |
| PMC11033503__F4 | C/EBPB: A transcription factor associated with the irreversible progression of Alzheimer's disease |
| PMC11034122__F6 | Comparative physiological, biochemical, metabolomic, and transcriptomic analyses reveal the formation mechanism of heartwood for Acacia melanoxylon |
| PMC11034122__F7 | Different pathways activated in A |
| PMC11034130__F2 | Lipid metabolism in tumor-infiltrating regulatory T cells: perspective to precision immunotherapy |
| PMC11034130__F3 | Lipid metabolism in tumor-infiltrating regulatory T cells: perspective to precision immunotherapy |
| PMC11034130__F4 | Lipid metabolism in tumor-infiltrating regulatory T cells: perspective to precision immunotherapy |
| PMC11034170__F3 | Updated mechanisms of MASLD pathogenesis |
| PMC11034561__F2 | HTRA1 can affect BrM morphology through cleavage of ECM (Fibronection) |
| PMC11034561__F3 | Progress in the Study of the Role and Mechanism of HTRA1 in Diseases Related to Vascular Abnormalities |
| PMC11034608__F7 | p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model |
| PMC11035622__F8 | Mitochondrial enzyme FAHD1 reduces ROS in osteosarcoma |
| PMC11035635__F2 | Core molecular mechanisms of different types of RCD and the potential CAF-derived molecules that regulate RCD |
| PMC11035723__F1 | Early dynamic changes to monocytes following major surgery are associated with subsequent infections |
| PMC11036006__F13 | Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation |
| PMC11036006__F4 | Diagram of “component-target-pathway” |
| PMC11036065__F2 | Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications |
| PMC11036351__F1 | Hyper-Responsive Chemiluminescent Probe Reveals Distinct PYRase Activity in Pseudomonas aeruginosa |
| PMC11036658__F9 | Targeted inhibition of the PI3K/AKT/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer |
| PMC11036733__F6 | Dengue virus pathogenesis and host molecular machineries |
| PMC11037034__F3 | Novel milestones for early esophageal carcinoma: From bench to bed |
| PMC11037416__F1 | Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages |
| PMC11037416__F2 | Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages |
| PMC11037416__F3 | Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages |
| PMC11037416__F5 | Pyroptosis mediates macrophage reprogramming of the tumour immune microenvironment |
| PMC11039397__F7 | Mechanism diagram of SR1 alleviating bone lossIn the natural environment, air pollutants contain different AhR ligands |
| PMC11039397__GA1 | StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NFKB/p-ERK MAPK-NFATc1 signaling pathway |
| PMC11039815__F1 | Harnessing the cGAS-STING pathway to potentiate radiation therapy: current approaches and future directions |
| PMC11039819__F2 | Interplay between autophagy and cGAS-STING signaling and its implications for cancer |
| PMC11039848__F2 | How traditional Chinese medicine can prevent recurrence of common bile duct stones after endoscopic retrograde cholangiopancreatography? |
| PMC11039944__F2 | Alpha-fetoprotein in the tumor microenvironment of hepatocellular carcinoma |
| PMC11039990__F7 | Genomic overview of INA-induced NPR1 targeting and transcriptional cascades in Arabidopsis |
| PMC11039994__F8 | Levels of p53 govern the hierarchy of DNA damage tolerance pathway usage |
| PMC11040167__F6 | Nrf2/ARE pathway as a potential target to ameliorate atrazine-induced endocrine disruption in granulosa cells |
| PMC11040290__F1 | Emerging role of galectin 3 in neuroinflammation and neurodegeneration |
| PMC11040299__F1 | Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease |
| PMC11040302__F1 | Application of artificial hibernation technology in acute brain injury |
| PMC11040350__F1 | Platelet Membrane Nanocarriers Cascade Targeting Delivery System to Improve Myocardial Remodeling Post Myocardial Ischemia–Reperfusion Injury |
| PMC11040418__F2 | Network pharmacological analysis of chondrocyte apoptosis modulation by RJNTF |
| PMC11040904__F2 | Regulatory pathways governing PD-L1 via phosphorylation and ubiquitination |
| PMC11040904__F3 | Negative regulatory pathways of PD-L1 mediated by other posttranslational modifications |
| PMC11040904__F4 | Regulatory pathways of PD-L1 via deubiquitination |
| PMC11040904__F5 | Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways |
| PMC11040904__F6 | Positive regulatory pathways of PD-L1 mediated by other posttranslational modifications |
| PMC11040904__F7 | Posttranslational modification of PD-1 |
| PMC11040941__F6 | C6orf15 promotes liver metastasis via WNT/Beta-catenin signalling in colorectal cancer |
| PMC11042021__F7 | KEGG pathway diagram for graft-vs.-host disease depicting the complex interplay of cellular and molecular interactions involved in the pathogenesis of graft-vs.-host disease (GVHD) |
| PMC11042021__F8 | KEGG pathway diagram for antigen processing and presentation illustrating the central processes involved in antigen processing and presentation, which are essential for immune system function |
| PMC11042222__F4 | Loss of Ffar4 is associated with decreased AMPK signaling and increased cellular senescence in the infarcted myocardium |
| PMC11042502__F2 | Fructose impairs fat oxidation: Implications for the mechanism of western diet-induced NAFLD |
| PMC11042538__F2 | Cellular senescence in cancer: molecular mechanisms and therapeutic targets |
| PMC11043956__F7 | SSYYJN ameliorates CKD-induced muscle atrophy by inhibiting ferroptosis in tibialis anterior muscle cell via HIF-1A/SLC7A11 pathway |
| PMC11043957__F1 | Signaling pathways in radiation-induced lung injury |
| PMC11043957__F2 | Nrf-2 and signaling pathways |
| PMC11044150__F10 | Modulating the MAPK signaling pathway of LQZ against AD |
| PMC11044490__F6 | DEGs in plant hormone signal transduction pathway |
| PMC11045263__F1 | Mechanisms underlying enhanced immunotherapy efficacy through exercise |
| PMC11045904__F2 | Inflammatory signaling pathway involved in AD is depicted in the figure |
| PMC11045904__F3 | Intricate relationship between the gut and brain axes in PD is delineated by the schematic signaling pathway, with a focus on the inflammatory cascade triggered by dysbiosis at the gut lumen and BBB |
| PMC11046063__F1 | NRF2 signalling pathway |
| PMC11046441__F3 | Diversity of metabolic arrangements for Alpha-glucan and disaccharide pathways in the context of prokaryotes |
| PMC11046830__F2 | Glycocalyx degradation in LPS or septic conditions |
| PMC11046830__F3 | Oxidative stress response in ECs |
| PMC11046830__F4 | Cascade of effects resulting from the release of IL-33 under the action of endothelial injury and other factors |
| PMC11046856__F1 | Canonical Wnt/Beta-catenin signaling pathway |
| PMC11046856__F2 | Non-canonical Wnt signaling pathways |
| PMC11046856__F4 | Crosstalk between Wnt/Beta-catenin, Notch, and TGFB signaling pathways during wound healing |
| PMC11046879__F2 | Illustrates the functions of PTEN in the cytoplasm and nucleus |
| PMC11046940__F2 | Mechanisms by which autophagy modulation affects chemosensitivity are multifaceted and involve multiple signaling pathways |
| PMC11046940__F3 | Regulation of autophagy to affect radiosensitivity involves a complex network of signaling pathway |
| PMC11047590__F1 | Redox systems involved in microglia |
| PMC11047590__F2 | Redox regulation of immunometabolism in the polarization of microglia in DR |
| PMC11048169__F1 | Main signaling pathways within cancer cells |
| PMC11048169__F3 | Information exchange and signal transmission between cells within the tumor microenvironment |
| PMC11048214__F5 | IPA canonical pathway analysis in genes containing prioritised variants |
| PMC11048239__F1 | Flux-independent signaling pathways activated by AMPARs in neurons |
| PMC11048239__F4 | Flux-independent signaling by NMDARs in neurons |
| PMC11048329__F2 | Schematic presentation of current evidence on Cx32 association with EMT and the HCC chemotherapeutic resistance with oxaliplatin or doxorubicin |
| PMC11048329__F3 | Schematic presentation of current evidence on Cx32 association with signaling pathways regulating proliferative and cell death processes |
| PMC11048425__F5 | Proposed metabolic routes associated with lipid and Beta-carotene biosynthetic pathways in ΔcarRP WJ11 in comparison with the WJ11 strain |
| PMC11048531__F2 | Combination of DSF/Cu and chemotherapeutic drugs sensitizes breast cancer (BC) cells and their stem cells by targeting various cellular and signaling mechanisms |
| PMC11048596__F4 | Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma |
| PMC11048596__F5 | Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma |
| PMC11048596__F6 | Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma |
| PMC11048686__F1 | Vitamin D synthesis pathway |
| PMC11048799__F5 | Mechanism by which GAA promotes muscle development and growth through mirNA-targeted gene regulatory signaling pathway [27,43,44,47,48,49,50,51] |
| PMC11049012__F1 | BCG-driven activation of the bladder cancer TME involves the NFKB/TNFA signaling pathway and IRFs/IFN pathway |
| PMC11049046__F5 | KEGG pathway of the MAPK signaling pathway with target genes of our known miRNAs shown in red stars and targets of novel miRNA NC_060925 |
| PMC11049046__F6 | KEGG pathway of the PI3K-Akt signaling pathway with target genes of our known miRNAs shown in red stars and targets of novel miRNA NC_060925 |
| PMC11049059__F8 | CCN1-mediated signaling pathway in pregnant women with SARS-CoV-2-infection |
| PMC11049089__F1 | Signaling cascades of TLR4 and TLR2 receptors |
| PMC11049334__F2 | Polyphenol-target network and associated signaling pathway and biological function |
| PMC11049451__F3 | Estrogen biosynthesis pathway from cholesterol to estetrol with the enzymes involved |
| PMC11049850__F3 | Molecular mechanisms of LPS bacterial interaction with dental stem cells |
| PMC11049885__F2 | Network comprised of the IRs affecting ecdysone synthesis |
| PMC11049885__F3 | Network comprised of the IRs that compete with ecdysone synthesis |
| PMC11049885__F6 | Key IRs significantly affecting ecdysone synthesis |
| PMC11049926__F4 | General model of neuroinflammation in epilepsy |
| PMC11049935__F5 | Plant hormone signaling pathways and related DEGs |
| PMC11050151__F2 | Representative scheme of the 15 genes shared by the selected pathways using pathway enrichment analysis |
| PMC11050151__F3 | Gene association networks that result from entering the list of eight genes—PIK3CG, PTGS2, FOS, PTPRC, VAV1, ITPR3, NFATC2, and PIK3R2—as input into the GeneMANIA software |
| PMC11050203__F1 | Activated signaling pathways: (a) the Wnt signaling pathway is activated in the presence of Wnt |
| PMC11050207__F4 | Significantly altered KEGG pathways in LAPST versus CPG group comparison |
| PMC11050207__F5 | Significantly altered KEGG pathways in LAPST vs |
| PMC11050257__F2 | Androgen receptor structure and signaling pathway in PCa |
| PMC11050257__F3 | Representation of the diversity of the AP-1 family of TF |
| PMC11050257__F5 | MYC protein and its signaling pathway |
| PMC11050262__F14 | Cytotoxic effect of cisplatin on the HT-29 cell line based on gene expression and pathway analysis |
| PMC11050262__F8 | Gene expression changes in GO terms: (A) base excision repair, (B) mismatch repair, and (C) homologous recombination pathways in response to high–THC extract #18 compared to DMSO control in the HT–29 CRC cell line |
| PMC11050296__F10 | Scheme showing the mechanism of olive-derived secoiridoids that regulate melanogenesis signaling pathway |
| PMC11050413__F10 | Mechanistic map illustrates the role of NDUFA6-DT as a sponge for miR-455-3p in gliomas, disrupting its ability to suppress YWHAH/YWHAG expression |
| PMC11052371__F3 | Pathogenesis of acne and the mechanism of action of P |
| PMC11052502__F4 | Results of PPI, KEGG, Reactome, and GO analysis of 19 common proteins that were targets of 1-MNA and RA-associated gene targets |
| PMC11053014__F1 | Model of Hippo sinaling pathway in mammalian cells and the activity of Hippo sinaling pathway controls the dynamic localization of YAP/TAZ between nucleus and cytoplasm |
| PMC11053014__F2 | Molecular mechanism by which mechanical cues regulate YAP/TAZ |
| PMC11053446__F10 | KEGG pathway analysis for DE mRNAs in tracheal tissues from chickens infected with IBV DMV/1639 or IBV Mass41 |
| PMC11053446__F6 | KEGG pathway analysis for DE mRNAs from cTECs infected with IBV DMV/1639 or IBV Mass41 |
| PMC11053566__F10 | Proposed mechanisms of action of eudesmane-type sesquiterpene lactones on the TNF-Alpha-induced NFKB signaling pathway |
| PMC11053710__F2 | Cross-talk of Dyrk1B in signaling pathways in development and disease |
| PMC11053886__F2 | Signaling related to flowering |
| PMC11053956__F6 | JAK/STAT signaling pathway mapper |
| PMC11054193__F7 | DEGs and DMs change following exogenous ABA therapy and UV-B stress in the R |
| PMC11054595__F2 | Mechanisms or pathways associated with sepsis-induced ALI |
| PMC11054859__F5 | KEGG pathway (hsa05200 pathway in cancer) |
| PMC11054859__F6 | KEGG pathway (hsa05226 gastric cancer) |
| PMC11054859__F7 | KEGG pathway (hsa04151 P13K-AKT signaling pathway) |
| PMC11055311__F1 | Main signaling pathways involved in TPL in cancer |
| PMC11055549__F3 | Construction of the prognostic target-ingredient network |
| PMC11055915__F4 | Mitochondrial quality control regulates cell death induced by copper and iron |
| PMC11055934__F1 | Depicts the eicosanoid inflammatory pathway |
| PMC11055934__F4 | illustrates the various components of the p53 regulatory pathway and relevant polymorphisms associated with ISFO |
| PMC11056316__F9 | Schematic illustration outlining the mechanism by which PIN operates during osteoclastogenesis |
| PMC11056518__F3 | IL-23 and IL-12 and their receptors, with summary of associated effector cells, cytokines, and immune function |
| PMC11056704__F8 | Graphic illustration for role of oestrogen‐induced exosomal SNHG17‐CCL13‐CCR2‐M2 macrophage axis in ovarian cancer |
| PMC11056900__F1 | Molecular mechanism of mitochondrial dysfunction modulating the relationship between chronic liver disease |
| PMC11056900__F2 | Endoplasmic reticulum dysfunction modulates chronic liver disease |
| PMC11056900__F3 | Mitochondrial and endoplasmic reticulum-associated signaling regulates the molecular mechanism of chronic liver disease |
| PMC11057055__F5 | Identification of microRNA (miRNA) target genes |
| PMC11058197__F6 | Proposed model of the Notch-ROCK pathway and its biological significance |
| PMC11058230__F7 | A hypothetic model for signaling pathway alterations and cellular phenotypes in MPS II neurons |
| PMC11058355__F2 | Functions of Mincle |
| PMC11058607__F2 | Pathways in HNSCC cells involving growth factor receptors like TGFB causing cell migration and invasion leading to metastasis |
| PMC11058799__F7 | Gene network crosstalk between selected DEGs (TYK2, STAT1 and TLR7) created with NetworkAnalyst software [44] |
| PMC11058998__F3 | Piezo1 affects the occurrence and development of diseases through multiple signaling pathways |
| PMC11058998__F4 | Pleiotropic physiological functions of Piezo1 in human body and its effect on malignant behavior of tumors |
| PMC11060011__F8 | Molecular action schematic |
| PMC11061161__F1 | T cell activation and subset differentiation and function by lipid metabolism |
| PMC11061161__F3 | Amino acid metabolism modulates T cell survival and lineage commitment |
| PMC11061361__F2 | LIPUS holds potential as an effective approach to counteract synovial inflammation and fibrosis |
| PMC11061361__F3 | LIPUS regulates chondrocyte function via multiple pathways |
| PMC11062136__F1 | Graphical model illustrating the complex roles of Cytokinin Response Factors (CRFs) in the trade-off between abiotic stress response and plant developmental processes |
| PMC11062289__F5 | ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency |
| PMC11062983__F7 | pDNA-tachyplesin treatment stimulates the immune system and increases the probability of apoptosis in MC4-L2 tumor cells |
| PMC11063341__F1 | Mechanism of Hippo pathway and the hippo targets of ncRNAs |
| PMC11063389__F2 | Therapeutic targets and inhibitors targeting JAK2/STAT3 signaling pathway for TNBC treatment |
| PMC11063508__F1 | Schematic diagram of the entire study |
| PMC11063913__F1 | Regulatory mechanisms of cytokines in male sex determination in mice |
| PMC11063913__F2 | Regulatory mechanisms of WT1 in sex differentiation |
| PMC11063913__F4 | Regulatory mechanisms of SOX9 in sex differentiation |
| PMC11063913__F5 | Graphical summary During sex determination in the male embryo, the expression of numerous cytokines at specific times and spaces act together to regulate the lineage differentiation of Sertoli cells |
| PMC11064142__F10 | TLR signalling leads to apoptosis in tumour cells |
| PMC11064142__F8 | A) Interaction of mir15a/16-5p cluster and mir-7641 with targeted genes involved in intrinsic and extrinsic signalling pathways of apoptosis |
| PMC11064393__F1 | CGAS-STING signaling pathway |
| PMC11064406__F3 | Intracellular copper distribution pathways |
| PMC11064406__F4 | Molecular mechanisms of cuproptosis |
| PMC11064802__F1 | Action of TCM prescriptions and natural bioactive molecules in atherosclerosis therapy by targeting peroxisome proliferator-activated receptors (PPARs) |
| PMC11064802__F7 | Action of carbohydrates in atherosclerosis therapy |
| PMC11065696__F7 | Mechanistic scheme of UBB in ccRCC |
| PMC11065698__F1 | 5-LO-dependent oxylipin formation from ARA, EPA and DHA |
| PMC11068999__F2 | Wnt/Beta-catenin pathway |
| PMC11068999__F4 | Hh signaling pathway |
| PMC11074409__F2 | Activity of probiotics, synbiotics and postbiotics |
| PMC11074473__F3 | M5C methylation in innate immunity (By figdraw |
| PMC11074996__F1 | The multi-modular engineering and efflux strategies for lycopene synthesis in Saccharomyces cerevisiae |
| PMC11076649__F8 | JCYSTLF exerted an anti-senescence effect through regulating the HIF-1A/autophagy pathway in diabetic kidneys |
| PMC11076692__F1 | Genes and mechanisms of sex determination |
| PMC11076692__F2 | 46,XX Testicular and ovotesticular DSD |
| PMC11076696__F2 | GLP-1RAs in protecting endothelial cell function |
| PMC11076696__F3 | GLP-1RAs in reducing macrophage inflammation and foam cell formation |
| PMC11076710__F9 | Nrf2/ARE signaling pathway, mitochondrial ROS, and NLRP3 inflammasome in renal tubular epithelial cells under high lipid conditions |
| PMC11076713__F8 | Schematic model: The interferon and interleukin 27-dependent JAK-STAT signaling pathway |
| PMC11076734__F4 | PINs-mediated auxin transport regulation during salt stress |
| PMC11076791__F4 | Proposed regulatory network |
| PMC11077368__F11 | Schematic diagram explains the mechanism underlying by which SP protects against colitis |
| PMC11077374__F1 | LncRNAs in modulating the Wnt/Beta-catenin signaling pathway in pancreatic cancer |
| PMC11077374__F3 | HuR during Wnt/Beta-catenin signaling pathway, autophagy and drug resistance in pancreatic cancer |
| PMC11077374__F4 | FOXO1 and FOXO3 in regulating Wnt/Beta-catenin signaling pathway and autophagy in pancreatic cancer |
| PMC11077374__F5 | FOXM1 in regulating Wnt/Beta-catenin signaling pathway and autophagy in pancreatic cancer |
| PMC11077374__F7 | HIF in regulating Wnt/Beta-catenin signaling pathway and autophagy in pancreatic cancer |
| PMC11077374__F8 | FOXO3-FOXM1 axis in regulating drug resistance in pancreatic cancer |
| PMC11077380__F2 | Mechanism diagram illustrates the crosstalk between Se-AA metabolism and various cell types in the TME |
| PMC11077380__F3 | Antitumor application of Se-AAs |
| PMC11077654__S1 | Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus |
| PMC11079205__F1 | Bone remodeling is a dynamic process that is completed with the participation of BMU |
| PMC11079205__F2 | The GM and gut hormones on bone metabolism |
| PMC11079205__F3 | GLP-1 effects on bone |
| PMC11079205__F4 | Incretin hormones’ effect on bone |
| PMC11079208__F3 | HER-2/EGFR signaling pathway in breast cancer |
| PMC11079208__F5 | Mapping the function of MicroRNAs as a critical regulator of tumor-immune cell communication in breast cancer and potential treatment strategies |
| PMC11079285__F2 | TREM2, as an oncogene, promotes the progression of PTC, GC, PRAD, RCC, EAC, and BCC by activating the PI3K/Akt, NFKB, and JAK/STAT3 signaling pathways, respectively |
| PMC11079285__F3 | TREM2 mediated immunosuppression and regulation of cancer progression |
| PMC11079312__F8 | Proposed lipogenic pathway regulated by MUL1 during conditions of HFD |
| PMC11079401__F2 | MiRNAs in EMT regulation via TGFB signaling pathway in pancreatic tumor cells |
| PMC11079401__F3 | MiRNAs in EMT regulation via PI3K/AKT signaling pathway in pancreatic tumor cells |
| PMC11079401__F4 | MiRNAs in EMT regulation via WNT and JAK/STAT signaling pathways in pancreatic tumor cells |
| PMC11082402__F5 | Riboflavin metabolic pathway |
| PMC11082748__F4 | Graphical representation of the CREB signaling pathway downregulated in the control group (see Figure 3A) |
| PMC11082748__F5 | Genes (N = 21) detected by IPA as involved in the neuroimmune pathway were entered into a representation using the GeneMANIA algorithm |
| PMC11083344__F4 | BCAR3 in cell cycle progression |
| PMC11083345__F5 | DEGs and DEPs involved in Alpha-linolenic acid metabolism, terpenoid biosynthesis and phenylalanine metabolism pathway |
| PMC11083429__F1 | When a DNA single-strand break (SSB) happens, poly (ADP-ribose) polymerase (PARP) guides SSB repair through NAD+poly(ADP-ribosyl)ation (PARylation) of histones and chromatin remodeling enzymes |
| PMC11083431__F6 | Possible gene expression changes from enhanced NRF2 signaling and depleted NOTCH signaling in the bile acid synthetic pathway from cholesterol in Keap1F/F::RbpjF/F::AlbCre liver at 3 W of age |
| PMC11083511__F1 | Subsets and functions of CD4+ T cells |
| PMC11083682__F2 | Influenza viral degradation of cellular proteins involved in the interferon responses |
| PMC11083682__F3 | Influenza viral degradation of cellular proteins that do not directly regulate IFN signaling |
| PMC11083695__F1 | Canonical hedgehog signaling pathway acts after the hedgehog (HH) ligands join the Patched-1 (PTCH-1) to release Smoothened (SMO) and enhance the translocation of glioma-associated oncogene (GLI) into the nucleus |
| PMC11083695__F2 | Reappraisal of the Roles of the Sonic Hedgehog Signaling Pathway in Hepatocellular Carcinoma |
| PMC11083860__F8 | FGF23/FGFR1cAklotho signalling pathway which mediates phosphorylation of NHERF1 |
| PMC11084201__F18 | Mechanisms of MPs’ impacts on the liver |
| PMC11084272__F7 | Action of multifunctional FYD in preventing cancer metastasis |
| PMC11084413__F5 | KEGG pathway analysis of carnosic acid downregulated proteins associated with glycolysis/gluconeogenesis |
| PMC11084446__F8 | Brief diagram of the proposed therapeutic effect of the LiESWT in improving detrusor hyperactivity via TRPV channels and the cellular signaling pathway involved in regulating intracellular Ca2+ oscillation in a rat model of OHD-induced DHIC |
| PMC11084561__F3 | Two consecutive signals are requisite for inflammasome activation |
| PMC11084589__F2 | Inhibition of pathway activity induces microglial cell state transition |
| PMC11084589__F3 | Increased pathway activity induces a shift from a neurotoxic to a neuroprotective state in microglia |
| PMC11084589__F4 | Possible targeting pathway of ABA in PD |
| PMC11085123__F1 | Biosynthetic pathway of terpenoids (A), alkaloids (B), and phenylpropanoids (C) in plants |
| PMC11085166__F2 | Keap1-Nrf2 signalling pathway for gene expression control |
| PMC11085255__F1 | Molecular structure and signaling pathway activation mechanism of Nrf2 |
| PMC11085255__F2 | Regulation mechanism based on Nrf2 signal pathway |
| PMC11085255__F3 | Effects of natural products targeting Nrf2-related signaling pathway on myocardial ischemia |
| PMC11085419__F5 | Gallic Acid Can Promote Low-Density Lipoprotein Uptake in HepG2 Cells via Increasing Low-Density Lipoprotein Receptor Accumulation |
| PMC11087094__F3 | Four most related metabolic pathways in digestive system tumors |
| PMC11087094__F4 | Three greatly important metabolic pathways in digestive system tumors |
| PMC11087106__F7 | High-dose Vitamin C injection ameliorates against sepsis-induced myocardial injury by anti-apoptosis, anti-inflammatory and pro-autophagy through regulating MAPK, NFKB and PI3K/AKT/mTOR signaling pathways in rats |
| PMC11087724__F1 | AMPK/mTOR signaling pathway involved in regulation of feed intake in chickens (created with BioRender |
| PMC11087724__F2 | Leptin and insulin signaling pathways in the hypothalamus of chickens regulating neuropeptide genes (created with BioRender |
| PMC11087724__F3 | Detailed leptin signaling pathway in the hypothalamus of chickens (adapted from “Cytokine Signaling through the JAK-STAT Pathway”, by BioRender |
| PMC11087971__F4 | The ECM-receptor interaction pathway and (B) the IL-17 signaling pathway |
| PMC11088339__F2 | The transforming growth factor B (TGFB) signaling pathway in cardiac fibrosisTGFB regulate phenotypes of the cells through activation of mothers against decapentaplegic (SMAD)-related pathway together with p38 pathway |
| PMC11088339__F5 | Therapeutic application of adipose-derived stromal vascular fraction in myocardial infarction |
| PMC11088914__F3 | The interaction of the lipid pathway with other signaling pathways for the regulation of pluripotency |
| PMC11089157__F3 | Transcriptional regulation of FOXK2 |
| PMC11089157__F4 | Post-translational regulation of FOXK2 |
| PMC11089157__F5 | Emerging roles of FOXK2 in cancers and metabolic disorders |
| PMC11089204__F5 | Proposed metabolic pathway of psilocybin and its active metabolite psilocin |
| PMC11091328__F1 | Regulatory mechanisms of SIRT1 on ER stress and NFKB signaling pathways |
| PMC11091639__F8 | PD-L1 regulatory signaling pathway [23] |
| PMC11092382__F2 | Antitumor effects of sophocarpine through multiple signaling pathways |
| PMC11092636__F3 | Exercise activates the EGFR/insulin signaling |
| PMC11095602__F2 | Senescence-associated lymphoma progression and drug resistance |
| PMC11095605__F2 | Activation and inhibition of the Wnt/Beta-catenin signaling pathway |
| PMC11097647__F6 | B cell receptor signaling pathway-enriched Module_01 |
| PMC11098157__F1 | Metabolic pathway for S‐warfarin |
| PMC11098888__F4 | CCL1/CCR8, CCL3/CCR5, CXCL6/CXCR2, and CXCL12/ CXCR4 axes in esophageal squamous cell carcinoma |
| PMC11099588__F1 | Biological functions of Amot family proteins and associated signal transduction pathways |
| PMC11099600__F4 | KEGG Pathway Analysis of ultravist-treated mast cells |
| PMC11101339__F4 | KRAS pathway and KRAS inhibitors |
| PMC11101339__F5 | Main mechanisms of therapy targeting TME in SMARCA4-UT |
| PMC11103046__F1 | Cardioprotective Mechanisms of SGLT2 Inhibitors Against Cancer Treatment–Induced CardiotoxicitySodium-glucose cotransporter-2 (SGLT2) inhibitors protect against cardiovascular toxicity induced by anticancer drugs via multiple mechanisms |
| PMC11103046__F2 | The Anticancer Effects of SGLT2iSGLT2 inhibitors (SGLT2i) inhibit glucose uptake by inhibiting SGLTs (SGLT-1 and SGLT-2) and glucose transporters (GLUTs) |
| PMC11103502__F9 | Pharmacological activation of the HIF pathway improves the ischemic tolerance of brain-resident cells by reprogramming of glucose metabolism |
| PMC11103679__F1 | Direct and indirect mechanisms of androgen signalling |
| PMC11106351__F9 | Anti-hepatitis B virus mechanism of dopamine |
| PMC11106741__F1 | Esc in cancer cells was revealed to be related to apoptosis, which is governed by the mitochondrial pathway, ER stress and ferritinophagy |
| PMC11106741__F2 | Esc, a compound with potential anticancer properties, promotes apoptosis and inhibits the proliferation of tumor cells |
| PMC11107893__F1 | Molecular targets and therapeutic interventions in non-small cell lung cancer treatment |
| PMC11116266__F2 | JAK STAT signaling proteins in spondyloarthropathy and possible mechanisms of action of the JAK inhibitors |
| PMC111167__F1 | BR biosynthesis pathway |
| PMC11117599__F1 | Anti-fibrosis and fibrogenesis mechanisms of NO/NOS system |
| PMC11117599__F2 | Anti-fibrosis mechanisms of CO |
| PMC11117599__F3 | Anti-fibrosis mechanisms of H2S |
| PMC11117599__F4 | Anti-fibrosis mechanisms of H2 in fibrotic diseases |
| PMC11117599__F5 | SO2 exerts its antifibrotic effects by modulating key intracellular signaling cascades |
| PMC11117611__F3 | NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases |
| PMC11117611__F4 | NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases |
| PMC11117611__F5 | NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases |
| PMC11117611__F6 | NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases |
| PMC11117676__F2 | The nuclear signaling pathway of RIP-mediated EpCAM |
| PMC11117695__F9 | MAs protect IPEC-1 cells from H2O2-induced oxidative stress, inflammation and tight junction protein disruption via activating the Nrf2 pathway to inhibit the ROS/NLRP3/IL-1B signaling pathway |
| PMC11117976__F1 | TLR and NOD receptor-mediated immune response |
| PMC11117976__F3 | NETosis in neutrophils |
| PMC11117976__F5 | M2 macrophage polarization |
| PMC11117976__F8 | Immune suppression during bacterial infection |
| PMC11118191__F2 | Overview of USP36-mediated signaling pathways |
| PMC11118937__F1 | Nrf2 signaling in mitigating heat stress and xenobiotic-induced oxidative distress and apoptosis |
| PMC11118972__F5 | Effect of pteF deletion on cell metabolism |
| PMC11119514__F1 | RDNVs reverse osteoporosis by potentiating osteogenic differentiation of hBMSCs via targeting estrogen receptor A (ERA) signaling |
| PMC11119800__F1 | Involvement of OGT in hepatic cellular stress |
| PMC11119800__F2 | OGT is required for the development of infectious liver diseases |
| PMC11119800__F3 | OGT contributes to the progression of NAFLD |
| PMC11119800__F4 | OGT has dual effects on liver fibrosis |
| PMC11119800__F5 | Biological function of OGT in HCC |
| PMC11119900__F3 | PAI-1 alters TME and regulates tumor cell migration and invasion |
| PMC11120013__F2 | Comparing Redox and Intracellular Signalling Responses to Cold Plasma in Wound Healing and Cancer |
| PMC11120013__F4 | CP-derived RONS promote cancer cell autophagy and death by activating the mitogen-activated protein kinase (MAPK) family signalling pathways |
| PMC11120279__S1 | FDT vaccine with the ability to activate systemic immunity for tumor inhibition |
| PMC11120359__F1 | Representation of the signaling pathway in the activation of CXCR4 (left) and ACKR3 (right) |
| PMC11120609__F1 | Metabolic pathway of cyclophosphamide |
| PMC11120667__F11 | Proposed model of the mechanisms of action of male M |
| PMC11120667__F12 | Proposed model of the mechanisms of action of female M |
| PMC11121000__F1 | Insights into Salinity Tolerance in Wheat |
| PMC11121022__F1 | Systemic sclerosis, recognized as a prototypical autoimmune disease, is intricately governed by a myriad of autoimmune mechanisms |
| PMC11121230__F2 | SHIP1 and SHIP2 in the PI3K/AKT signaling pathway (created with BioRender |
| PMC11121235__F8 | N-glycan metabolic pathway |
| PMC11121248__F7 | Two separate mechanisms for the role of MerTK and ENG in TNBC progression |
| PMC11121563__F1 | Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review |
| PMC11121563__F2 | Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review |
| PMC11121563__F3 | Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review |
| PMC11121563__F4 | Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review |
| PMC11121637__F1 | Schematic representation illustrates the role of miRNAs in the regulation of FOSL1 |
| PMC11121637__F4 | FOSL1 in promoting drug resistance and radio resistance |
| PMC11123779__F5 | Protein–protein gene network in RA-infected ducks |
| PMC11123998__F5 | Supplementation influences the metabolic reprogramming of cumulus cells in aging ovarian patients |
| PMC11124330__F17 | This study |
| PMC11124422__F2 | Mechanism by which APS induces apoptosis in cancer cells by interfering with the cell cycle, inhibiting signal transduction pathways, and inducing apoptosis |
| PMC11124422__F3 | APS on ICIs, CAR-T therapy, and DC cancer vaccines within the TME |
| PMC11125340__F7 | Platelet-Derived Growth Factor Receptor Beta and JAK2/STAT3 Pathway |
| PMC11125634__F3 | Schematic representation for DOCK11 and its partner AGAP2 regulating ARF1 activity to facilitate HBV retrograde trafficking |
| PMC11125634__F4 | Proposed hypothesis explains the mechanism for the role of DOCK11 in HBV cccDNA formation and its modulation of histone modifications and RNA Pol II on HBV cccDNA |
| PMC11125669__F1 | Pattern recognition receptors (PRRs) involved in intracellular viral sensing and downstream signaling |
| PMC11125855__F1 | Intracellular DNA sensors involved in the activation of IFN signaling and the NFKB pathway |
| PMC11125855__F3 | Inhibition of DNA-sensing pathways by KSHV viral proteins |
| PMC11125956__F11 | Osteoblasts in Rheumatoid Arthritis Pathway |
| PMC11125956__F13 | B Cell Receptor Signaling Pathway, KEGG |
| PMC11125956__F7 | T helper 1 Activation Pathway |
| PMC11125956__F8 | T helper 2 Activation Pathway |
| PMC11126050__F7 | KIT structure and signalling |
| PMC11126064__F8 | Hepatoprotective Effects of Allicin on Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Inhibiting Oxidative Stress, Inflammation, and Apoptosis |
| PMC11126125__F4 | Immune response induced by DTMUV infection and its immune evasion |
| PMC11126959__F2 | Biosynthesis of O-GlcNAc |
| PMC11126959__F3 | Autophagy pathway |
| PMC11126959__F4 | Impact of sustained changes in cardiac O-GlcNAcylation |
| PMC11127239__F2 | Cytotoxic effects of deoxynivalenol (DON) and mechanisms of diarrhea induction |
| PMC11130833__F1 | Molecular activity of BTK- and BCL2- inhibitors in CLL |
| PMC11130840__F1 | PCP-mediated signaling pathway in Drosophila and mouse |
| PMC11130926__F1 | Bacterial Q de novo and salvage pathways |
| PMC11132832__F5 | Hub target-pathway network (67 nodes and 95 edges) |
| PMC11134594__F2 | TGFB signaling pathway: Integrins release TGFB by binding to LLC on ECM |
| PMC11141153__F6 | AMPK signaling pathway depicted using KEGG in tissue lysate fractionThe levels of upregulation of the proteins observed in AMPK pathway are as follows: CAB39/MO25 log2 0 |
| PMC11141639__F1 | Winer et al |
| PMC11144369__F1 | Outlines of the AhR signaling pathway |
| PMC11144369__F2 | FICZ-induced, AhR-mediated skin carcinogenesis from UV radiation |
| PMC11147929__F6 | LSS affects endothelial cell pyroptosis through IKKE/STAT1/NLRP3 signaling pathway |
| PMC11148314__F4 | Emerging Perspectives of YAP/TAZ in Human Skin Epidermal and Dermal Aging |
| PMC11149107__F1 | HER3 targeted therapies in the clinic and HER3 downstream signaling pathways |
| PMC11153983__F6 | Illustration of the mechanism of DHA inhibiting T-ALL cell viability, inducing ferroptosis by modulating the SLC7A11-GPX4 signaling pathway and provoking ER stress |
| PMC11155398__F2 | Biological significance manipulated by SUMOylation in tumors |
| PMC11155398__F4 | Biological functions of SUMOylation cascade in tumors |
| PMC11161882__F3 | Differentially regulated pathways obtained from IPA analysis A |
| PMC11165723__F3 | Journey of a generation: advances and promises in the study of primordial germ cell migration |
| PMC11170970__F6 | SH alleviates DSS‐induced colitis via the “SH‐gut microbiota‐5HIAA‐AhR axis |
| PMC11171322__F8 | Graphical overview of representative exclusively differentially expressed genes from our RNA sequencing data in the myeloid and lymphoid group that are clearly assigned to the BMP/TGFB signaling pathway |
| PMC11171484__F4 | Systemic inhibition of TGFB signaling in the fibrotic lung by pirfenidone and localized inhibition of TGFB signaling in the fibrotic niche by bexotegrast (A,B) |
| PMC11171594__F1 | TLR-mediated signaling |
| PMC11171836__F11 | Mechanism by which Pin1 regulates NAFLD |
| PMC11172074__F1 | Effect of miR-21 on the PTEN/AKT Signaling Pathway |
| PMC11172187__F1 | Gliogenic switch during brain development |
| PMC11172217__F10 | FGF5 promoting secondary hair follicle growth |
| PMC11172503__F1 | Nrf2 and NFKB signaling pathways by royal jelly (RJ) |
| PMC11172503__F2 | Anti-senescence effect and molecular mechanisms of royal jelly (RJ) and its components on cellular senescence, healthy aging, and longevity induced by endogenous and exogenous factors |
| PMC11172514__F1 | The mechanism regulating NLRP3 inflammasome activation in canonical, non-canonical, and alternate pathway |
| PMC11172598__F1 | Gene interaction network map of each group |
| PMC11172744__F7 | After TCR stimulation, two signaling pathways are induced via 3,4,5-triphosphate (IP3) and diacylglycerol (DAG) |
| PMC11172800__F3 | Significantly, DE genes (identified by KEGG) were involved in the bacterial invasion of epithelial cells signaling pathway during 8-week S |
| PMC11172918__F3 | Different signaling pathways activated by the binding of CGs and ROS to NKS |
| PMC11172918__F4 | Ouabain–NKA-induced changes in epithelial cultured cells MDCK |
| PMC11172960__F1 | Signaling pathways in psoriasis pathogenesis in keratinocytes |
| PMC11172960__F2 | Putative molecular targets and their associated signaling pathways for psoriasis in keratinocytes |
| PMC11172960__F4 | Molecular targets of natural product-derived compounds for psoriasis treatment |
| PMC11172987__F2 | Host Cell Death and Modulation of Immune Response against Mycobacterium tuberculosis Infection |
| PMC11173086__F9 | Proposed regulatory network of bulbil initiation in P |
| PMC11173094__F3 | Natural products that modulate specific proteins in the molecular pathway of inducing and inhibiting ferroptosis |
| PMC11173095__F3 | VEGF signaling pathway |
| PMC11173247__F8 | Wound-induced genes involved in plant–insect interactions in arabidopsis WT and lox2 mutants |
| PMC11173325__F1 | The mTOR signaling pathway and the cellular functions driven by the formation of its two main complexes, mTORC1 and mTORC2 |
| PMC11173325__F2 | Roles of mTORC1 and mTORC2 in regulating metabolic diseases, cancer, and aging |
| PMC11173950__F3 | Oxidative stress: Nrf2 signaling pathway (adapted from Hammad et al |
| PMC11174581__F1 | Promotion mechanisms of microecologics on sports performance |
| PMC11174683__F3 | Mechanistic map of signaling pathways associated with NPs for liver cancer treatment |
| PMC11174684__F5 | Schematic representation of the hypothetical signaling pathway activated under PEG-6000 treatment in Saragolla and Svevo cultivars |
| PMC11174690__F3 | Fas/Fasl signaling pathway by active ingredients in goji berries |
| PMC11174690__F4 | PI3K-Akt signaling pathway by active ingredients in goji berries |
| PMC11174690__F5 | SIRT signaling pathway by active ingredients in goji berries |
| PMC11174838__F3 | Resistance Exercise and Essential Amino Acid Intake on Muscle Quality, Myokine, and Inflammation Factors in Young Adult Males |
| PMC11174978__F3 | Understanding Fibrous Tissue in the Effective Healing of Rotator Cuff Injury |
| PMC11174998__F1 | One-carbon metabolism |
| PMC11175075__F1 | Jasmonic Acid on Stress Response and Quality Formation in Vegetable Crops and Their Underlying Molecular Mechanisms |
| PMC11177111__F0 | miR-1202 regulates BPH-1 cell proliferation, apoptosis, and epithelial-to-mesenchymal transition through targeting HMGCL |
| PMC11177172__F5 | Regulatory associations between protein-protein networks, based on the IPA Knowledge Base |
| PMC11177995__F8 | Schematic diagram for the mechanism underlying the apoVs-mediated rescue of the impaired OVX MSCs biological function and their capacity to improve osteoporosis |
| PMC11185840__F2 | Sphingolipid metabolic pathway |
| PMC11185840__F3 | Activation of the complement system and its functions |
| PMC11185840__F4 | Sphingolipids and complement components signaling in glioblastoma |
| PMC11186353__F3 | Illustration representing the sites of action of different polyphenols in asthma pathway |
| PMC11186353__F4 | Illustration representing the sites of action of different polyphenols in cancer pathway |
| PMC11186359__F8 | Schematic diagram showing how PM increases AREG-dependent glutamine metabolism and lung cancer proliferation |
| PMC11186373__F8 | Sodium chloride promotes macrophage pyroptosis and aggravates rheumatoid arthritis by activating SGK1 through GABA receptors Slc6a12 |
| PMC11186432__F4 | Different regulatory functions of F-box proteins in gastric cancer |
| PMC11187367__F6 | Summary of the findings |
| PMC11187369__F4 | Druggable toll-like receptor (TLR) cascades |
| PMC11187922__F9 | The main findings in this study |
| PMC11188434__F0 | GUP can effectively inhibit the activation of cGAS-STING pathway induced by multiple stimuli and reduce the expression of type I interferon and pro-inflammatory cytokines |
| PMC11192764__F1 | TGFB complex and TGFBR signaling pathways |
| PMC11192909__F0 | Mechanism of NGR1 in alleviating colitis |
| PMC11194209__F1 | Major abnormal signaling pathways in TNBC |
| PMC11195429__F1 | cGAS-STING and cell death pathways |
| PMC11195429__F2 | CGAS-STING signaling pathway |
| PMC11195429__F3 | Antitumor therapies awake the cGAS-STING signaling to accelerate the antitumor immunity |
| PMC11200706__F2 | Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes |
| PMC11200741__F1 | Canonical pathway (WNT/Beta-catenin pathway) |
| PMC11200741__F3 | Outline of the Hippo signalling pathway |
| PMC11200880__F1 | Oxytocin signaling brain pathway |
| PMC11200984__F6 | Action of Isoflavone Derived from Soy-Based Tempeh as an Antioxidant and Breast Cancer Inhibitor via Potential Upregulation of miR-7-5p: A Multimodal Analysis Integrating Pharmacoinformatics and Cellular Studies |
| PMC11201201__F2 | VEGFR activation by the VEGF family of growth factors and resulting downstream signaling pathways to angiogenesis and lymphangiogenesis |
| PMC11201249__F2 | Schematic presentation of mTOR modulation pathways |
| PMC11201617__F1 | Molecular Mechanisms in Tumorigenesis of Hepatocellular Carcinoma and in Target Treatments—An Overview |
| PMC11201617__F2 | Canonical activation of the WNT/Beta-catenin pathway |
| PMC11201617__F3 | Molecular Mechanisms in Tumorigenesis of Hepatocellular Carcinoma and in Target Treatments—An Overview |
| PMC11201617__F4 | Hippo signaling pathway |
| PMC11201617__F6 | Notch signaling pathway |
| PMC11201619__F2 | Targets to Search for New Pharmacological Treatment in Idiopathic Parkinson’s Disease According to the Single-Neuron Degeneration Model |
| PMC11201634__F1 | Canonical Wnt signaling pathway |
| PMC11201634__F2 | Wnt/Beta-Catenin Signaling Pathway in Pediatric Tumors: Implications for Diagnosis and Treatment |
| PMC11201634__F4 | An illustration of the specific Wnt signaling pathway associated inhibitors that have been studied in preclinical and clinical trials for pediatric tumors |
| PMC11201817__F2 | The influence of curcumin on mammalian DHA synthesis pathway and its neuroprotective effect [61] |
| PMC11201820__F1 | Relevant pathways and their targeted inhibitors (in red) for the EC |
| PMC11201820__F2 | Interaction between activated ECs and pericytes/vascular smooth-muscle cells (vSMCs) and their targeted inhibitors in red |
| PMC11201890__F2 | USP5 participates in immune regulation through a variety of signaling pathways |
| PMC11201989__F8 | Working model for PD-L1 in the regulation of ciliogenesis |
| PMC11202056__F8 | STRING pathway analysis depicting protein–protein interaction (PPI) networks |
| PMC11202101__F1 | Interleukin-17 signaling pathway (Kyoto Encyclopedia of Genes and Genomes (KEGG) ID: Human (Homo sapiens), hsa04657) |
| PMC11202107__F1 | Suppressor of Cytokine Signaling Proteins 3 and 5 Potentially Delineate Polarization of Th cells in Chronic Rhinosinusitis |
| PMC11202427__F1 | BMP pathway in cardiomyocyte differentiation |
| PMC11202427__F2 | WNT signaling pathway |
| PMC11202538__F1 | Canonical Shh signalling pathway |
| PMC11202538__F2 | Crosstalk with the Shh signalling pathway |
| PMC11202538__F3 | Targeting the Shh signalling pathway regulators |
| PMC11202552__F2 | Simplified diagram of the insulin signaling pathway |
| PMC11203016__F10 | Illustration of the Toll-like receptor signaling and apoptosis pathways in M |
| PMC11203611__F4 | Diagram of endocannabinoid biosynthesis and mode of action of the endocannabinoid system within a neuron |
| PMC11203709__F3 | VHL-mediated signaling/regulatory pathways in ccRCC with respect to PAX involvement |
| PMC11203986__F10 | DAXX-associated pathway |
| PMC11203986__F6 | CAF-1-associated pathway |
| PMC11203986__F7 | HIRA-associated pathway |
| PMC11203986__F8 | NAP1L1-associated pathway |
| PMC11204038__F1 | Schematic diagram showing the NAD+ metabolic pathway |
| PMC11204099__F8 | Chlorogenic acid and cinnamaldehyde synergism on Akt-mediated signaling pathway downstream target proteins |
| PMC11204236__F11 | Proposed model illustrating the network of molecular mechanisms governed by miR-1 during early differentiation of the cardiac sinoatrial region |
| PMC11204528__F8 | Dicerandrol C Suppresses Proliferation and Induces Apoptosis of HepG2 and Hela Cancer Cells by Inhibiting Wnt/Beta-Catenin Signaling Pathway |
| PMC11204910__F1 | Heme biosynthetic pathway in erythroid cells and the role of ATP-binding cassette transporter B7 (ABCB7 gene): The first enzyme of heme synthesis is 5-aminolevulinate synthase (ALAS2), which is the rate-limiting enzyme |
| PMC11205484__F2 | Biosynthetic Pathways of Protectins and Maresins in Macrophages and MaR-2 in Brown Adipose Tissue Activation |
| PMC11206024__F3 | TLR4 signaling pathway |
| PMC11206339__F1 | Common synthesis pathway for testosterone from cholesterol and its subsequent conversion into estrogenic and androgenic active metabolites |
| PMC11206395__F3 | Therapeutic mechanism of polyphenols for anxiety disorder |
| PMC11206589__F1 | Synergic Role of Dietary Bioactive Compounds in Breast Cancer Chemoprevention and Combination Therapies |
| PMC11206589__F2 | Suggested anticancer molecular mechanisms of bromelain |
| PMC11206589__F3 | Suggested anticancer molecular mechanisms of sulforaphane |
| PMC11206721__F1 | Nutrition-related signaling pathway leading to diabetic nephropathy |
| PMC11206879__F3 | Alterations in major signaling pathways that have been identified in OS development and metastasis: PI3K/AKT/mTOR, JAK/STAT, Wnt/Beta-catenin, NOTCH, Hedgehog/Gli, TGFB, MAPK, and receptor tyrosine kinases (RTKs) |
| PMC11206888__F7 | Diagram of PI3K–AKT signaling pathway |
| PMC11208122__F12 | Scutellarin alleviates microglia‐mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3B signaling pathway |
| PMC11208996__F1 | Schematic graph illustrating the TGFB/Smad signaling pathway and its roles in the regulation of various biological processes during chronic kidney disease |
| PMC11209433__F5 | Interactions among genes involved in the type 1 interferon signaling pathway using STRING (Search Tool for the Retrieval of Interacting Genes/Proteins) |
| PMC11210699__F2 | Therapeutic effects of baicalin and baicalein |
| PMC11210699__F3 | Therapeutic effects of baicalin and baicalein |
| PMC11210914__F1 | Ferroptosis |
| PMC11210914__F5 | Mitophagy in ferroptosis |
| PMC11210914__F7 | CMA- or TAX1BP1-mediated GPX4 degradation in ferroptosis |
| PMC11211258__F1 | Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment |
| PMC11211395__F2 | Dual role of sirtuins in cancer: biological functions and implications |
| PMC11211395__F3 | Dual role of sirtuins in cancer: biological functions and implications |
| PMC11211608__F2 | Understanding copy number variations through their genes: a molecular view on 16p11.2 deletion and duplication syndromes |
| PMC11211685__F4 | Fusarium mycotoxins: The major food contaminants |
| PMC11211685__F5 | Fusarium mycotoxins: The major food contaminants |
| PMC11211753__F6 | Possible mechanisms of action of TR for altering ECM turnover |
| PMC11212332__F7 | Characterisation of sRNAs enriched in outer membrane vesicles of pathogenic Flavobacterium psychrophilum causing Bacterial Cold Water Disease in rainbow trout |
| PMC11212664__F8 | Suppression of MyD88 disturbs gut microbiota and activates the NLR pathway and hence fails to ameliorate DSS-induced colitis |
| PMC11212700__F1 | From macroautophagy to mitophagy: Unveiling the hidden role of mitophagy in gastrointestinal disorders |
| PMC11212700__F2 | From macroautophagy to mitophagy: Unveiling the hidden role of mitophagy in gastrointestinal disorders |
| PMC11213636__F7 | Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGFB/Smad Signaling Pathway |
| PMC11214299__F3 | Exploiting the potential of the ubiquitin-proteasome system in overcoming tyrosine kinase inhibitor resistance in chronic myeloid leukemia |
| PMC11214400__F6 | Inflammatory loop involving Staphylococcus aureus, IL-36G, and cathepsin S drives immunity disorders in familial acne inversa keratinocytes |
| PMC11214488__F8 | GSK2334470 attenuates high salt-exacerbated rheumatoid arthritis progression by restoring Th17/Treg homeostasis |
| PMC11214942__F4 | Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions |
| PMC11214942__F5 | Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions |
| PMC11215075__F5 | Ezetimibe, Niemann-Pick C1 like 1 inhibitor, modulates hepatic phospholipid metabolism to alleviate fat accumulation |
| PMC11215092__F1 | Molecular pathways and targeted therapies in head and neck cancers pathogenesis |
| PMC11215396__F1 | CXCL8 and its cognate receptors CXCR1/CXCR2 in primary myelofibrosis |
| PMC11215460__F1 | Overexpression of Plakophilin2 Mitigates Capillary Leak Syndrome in Severe Acute Pancreatitis by Activating the p38/MAPK Signaling Pathway |
| PMC11215755__F1 | PI3K pathway in non-malignant cells and cancer |
| PMC11215755__F3 | Signalling and epigenetic mechanisms limiting the efficacy of PI3K inhibitors |
| PMC11216096__F1 | Wnt signaling in gastric cancer: current progress and future prospects |
| PMC11216096__F2 | Wnt signaling in gastric cancer: current progress and future prospects |
| PMC11216939__F2 | Interplay between the PI3K/AKT pathway and circadian rhythm regulators |
| PMC11220218__F1 | Metabolic reprogramming in thyroid cancer and therapeutic resistance |
| PMC11222861__F8 | Brief proposal model of altered epigenetic regulation mechanisms of histone H3K27 acetylation causing FLHS and a summarized workflow of comparative analysis of fatty liver disease among different species |
| PMC11223907__F1 | Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics |
| PMC11225869__F1 | In alveolar general capillary endothelial (gCap) cells, IGFBP7 prevents FBXW2-dependent ubiquitination and degradation of NFKB1/2 |
| PMC11232665__F2 | Intervertebral disc degeneration |
| PMC11232665__F3 | Mechanism of metformin in intervertebral disc degeneration |
| PMC11232665__F4 | Metformin likely acts on intervertebral disc degeneration through SIRT-related signalling pathways |
| PMC11232677__F7 | KEGG pathway analysis of differentially expressed genes on cell cycle pathway in AML patient group with high beta-catenin levels vs controls |
| PMC11232677__F8 | KEGG pathway analysis of differentially expressed genes on signaling pathways regulating pluripotency of stem cells in AML patient group with low beta-catenin levels vs controls |
| PMC11234204__F1 | Canonical mechanism of ferroptosis |
| PMC11234204__F3 | NRF2 is involved in preventing lipid peroxidation and ferroptosis in HCC |
| PMC11234204__F4 | Metabolic dysregulation mediates ferroptosis in HCC |
| PMC11234204__F5 | Regulatory factors involved in sensitivity and resistance to ferroptosis in HCC patients treated with sorafenib |
| PMC11234216__F3 | Signal mapping of transcription factors regulating the fate of HPCs |
| PMC11234281__F2 | Piezo1 located in different cells regulates bone formation |
| PMC11240352__F1 | Genetic and nongenetic mechanisms of CRC resistance to cetuximab |
| PMC11240352__F4 | Cetuximab mechanism of action and summary of how RAC1 and RAC1B could contribute to the known mechanisms of cetuximab resistance in CRC |
| PMC11240421__F13 | CK1A interplay in the NFKB pathway |
| PMC11240502__F1 | Effects of UVA and UVB radiation on skin tryptophan lead to pro-inflammatory pathways |
| PMC11240502__F2 | Tryptophan metabolites interact with AhR and potentially interfere with serotonin and melatonin synthesis |
| PMC11240630__F1 | Pathways associated with the signaling of BCSCs |
| PMC11240772__F1 | Active Canonical Wnt/Beta-Catenin Signaling Pathway |
| PMC11240772__F2 | Inactive Canonical Wnt/Beta-Catenin Signaling Pathway |
| PMC11240800__F2 | Abnormal signaling pathways contribute to the pathogenesis of uLMS |
| PMC11241178__F8 | Target pathway analysis of cordycepin combined with doxorubicin against breast cancer |
| PMC11241191__F7 | Schematic illustration of SRI regulating apoptosis in HCC |
| PMC11241432__F3 | MyD88-independent signaling pathway |
| PMC11241496__F2 | Targeted therapies in RAS-RAF-MAPK pathway |
| PMC11241496__F3 | Targeted therapies in the vascular endothelial growth factor (VEGF) pathway |
| PMC11241568__F2 | The JAK–STAT Pathway in Childhood B-Cell Acute Lymphoblastic Leukemia |
| PMC11242417__F1 | Macrophage origins and biological functions |
| PMC11242417__F3 | Signaling pathways of macrophage polarization |
| PMC11242587__F1 | Association of type 2 diabetes mellitus with cancer, for example, pancreatic cancer |
| PMC11242595__F2 | TGFB Modulated Pathways in Colorectal Cancer: New Potential Therapeutic Opportunities |
| PMC11244889__F8 | T3SS triggered LTB4 synthesis differs between neutrophils and macrophages |
| PMC11247318__F1 | Action in lymphoma |
| PMC11247557__F9 | Pyroptotic macrophages promote proliferation and chemotherapy resistance of peripheral T‐cell lymphoma via TLR4 signaling pathway |
| PMC1124928__F4 | Coagulation, fibrinolysis, and angiogenesis in cancer |
| PMC11251740__F1 | Clinically relevant dysregulated pathways in GBM |
| PMC11252768__F8 | Working summary of the study |
| PMC11257078__F1 | Species differences in bile acid synthesis |
| PMC11257078__F3 | Bile acid regulation of the autophagy-lysosome axis |
| PMC11257078__F4 | Bile acid crosstalk with sulfur amino acid metabolism |
| PMC11257964__F1 | Molecular machinery of apoptosis, pyroptosis, and necroptosis |
| PMC11257964__F4 | Targeting PANoptosis for cancer therapy |
| PMC11262449__F1 | Genes involved in glucose sensing, the reward system, sweet taste receptors, the endocannabinoid system, and insulin mediated glucose uptake found to have SNP associations with dietary sugar intake and/or cardiometabolic risk factors in children |
| PMC11263586__F5 | HPV perturbs DNA damage response signalling pathway |
| PMC11265800__F6 | Signaling pathways in melanoma cells and tissue |
| PMC11266911__F2 | Molecular mechanism of antitumoral properties of 6‐shogaol |
| PMC11273247__F11 | Sodium sulphate ameliorates hypercholesterolemia and hepatic insulin resistance in mice fed an HCD |
| PMC11273248__F1 | Flavonoid compounds exerting protective effects against brain injury after ICH |
| PMC11273248__F2 | Flavonoid compounds exerting protective effects on SAH |
| PMC11274024__F6 | Different cellular events in RG7388-resistant CLL samples |
| PMC11274073__F11 | Therapeutic Potential of Dalbergia pinnata (Lour.) Prain Essential Oil in Alzheimer’s Disease: EEG Signal Analysis In Vivo, SH-SY5Y Cell Model In Vitro, and Network Pharmacology |
| PMC11274091__F3 | Interrelationship of major pathways and coexisting inflammatory mediators between oxidative stress and inflammatory process in excisional skin wound healing |
| PMC11274159__F2 | EBV-affected signaling pathways associated with ferroptosis |
| PMC11274312__F6 | PPI network of the DEGs in immune-related pathways |
| PMC11274344__F6 | The cancer antioxidant regulation system in therapeutic resistance and scientific questions to be solved |
| PMC11274390__F1 | Zn and Cu in the synapse under physiological and pathophysiological conditions: (A) Roles of Zn and Cu under normal physiological conditions |
| PMC11274428__F1 | The PI3K/Akt/mTOR Axis in Head and Neck Squamous Cell Carcinoma |
| PMC11274491__F7 | Proposed scheme for the anti-angiogenic activities of PZ-DHA |
| PMC11274515__F1 | Signaling cascades of autophagy in hepatocellular carcinoma cells (HCCs) |
| PMC11274515__F3 | Various natural compounds (EGCG, emodin, quercetin and crocin) inhibit HCC through interconnected signaling pathways |
| PMC11274597__F1 | Outline of the HH signaling pathway [16] |
| PMC11274695__F3 | Interacting proteins in the classical cell signaling pathway validated using BiFC |
| PMC11274695__F4 | Protein interactions in plant hormone pathways confirmed using BiFC |
| PMC11274826__F3 | OPN in the regulation of various signaling pathways |
| PMC11274826__F4 | Diagrammatic representation of multifaceted function of OPN in various tumors |
| PMC11274826__F6 | Osteopontin: A Key Multifaceted Regulator in Tumor Progression and Immunomodulation |
| PMC11275100__F1 | PARPi effect in cancer cells and immune cells |
| PMC11275360__F3 | Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation |
| PMC11275360__F4 | lncRNA regulates adipocyte differentiation through TGFB/BMPs/Smad signaling pathway |
| PMC11275360__F5 | Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation |
| PMC11275360__F6 | Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation |
| PMC11275499__F1 | Antidepressant potential of ghrelin, which exerts neuroprotective effects by promoting neuronal proliferation and neurotrophic factor production in the brain |
| PMC11276060__F3 | LncRNAs in autophagy, apoptosis response, and inflammation of cells to bacterial invasion |
| PMC11276560__F5 | DEGs in selenium metabolic pathways of KEGG metabolic pathway map |
| PMC11276702__F7 | Gene expression of plant hormone biosynthesis pathway in the intraspecific hybrid fruit of H |
| PMC11276752__F1 | Deciphering Drug Resistance: Investigating the Emerging Role of Hyaluronan Metabolism and Signaling and Tumor Extracellular Matrix in Cancer Chemotherapy |
| PMC11276987__F10 | Lipids as signaling molecules that regulate metabolism |
| PMC11276987__F2 | Schema of pathways producing and utilizing endoplasmic reticulum (ER)-derived H2O2 |
| PMC11276987__F3 | Maladaptive UPR and endoplasmic reticulum (ER) stress-mediated inflammation |
| PMC11276987__F4 | Unfolded protein response signaling with their regulating microRNAs |
| PMC11276987__F5 | Cellular Senescence and Extracellular Vesicles in the Pathogenesis and Treatment of Obesity—A Narrative Review |
| PMC11276987__F7 | Adiponectin signal transduction [118] |
| PMC11277110__F2 | Roles of miRNAs involved in the developmental growth and apoptosis of Drosophila |
| PMC11277110__F4 | Signaling pathways regulated by miRNAs in wing development |
| PMC11277296__F2 | Mechanisms of mitochondrial dysfunction |
| PMC11277918__F2 | cGAS-STING can transform a cold tumor into a hot tumor and promote tumor cell apoptosis |
| PMC11278003__F5 | KEGGs pathway and GO molecular function (MF) analysis based on AD correlated interactors of Apaf-1 and TNFA |
| PMC11278074__F1 | Therapeutic approaches to vascular Ehlers–Danlos syndrome |
| PMC11278107__F3 | Antifibrotic activity of EchA in SSc model |
| PMC11278853__F1 | Schematic illustration depicting the potential anti-inflammatory effects of hypolipidemic agents primarily targeting LDL-C reduction |
| PMC11278853__F2 | Emerging evidence regarding the anti-cancer features of novel lipid-lowering treatments, including CETP inhibitors, bempedoic acid, and PCSK9 inhibitors |
| PMC11278952__F3 | Alterations of bile acids involved in the synthesis pathway in HD |
| PMC11279058__F2 | Mycoplasma hyopneumoniae generates immune evasion by modulating the host immune system |
| PMC11279438__F1 | Vitamin D’s role in skeletal muscle |
| PMC11279438__F2 | Relationship between oxidative stress and weakness of muscle |
| PMC11279438__F3 | Antioxidative role of vitamin D in muscle dysfunction |
| PMC11279831__F1 | IL-36 signaling pathway |
| PMC11279976__F2 | Common metabolic pathways of NAD+ and NMN |
| PMC11280061__F6 | Auxin-regulated TFRN attenuates lignin biosynthesis |
| PMC11280061__F7 | Auxin-regulated TFRN attenuates ABA transport, conjugation and signaling |
| PMC11280205__F5 | Mechanism in the development of a higher 2D:4D ratio |
| PMC11280308__F3 | Mechanisms of action of the A |
| PMC11280316__F8 | Suggested schematic illustration of the mechanism by which crocin could induce cell survival and exert anti-oxidative and anti-inflammatory effects in stressed cardiomyocytes |
| PMC11280978__F1 | Mechanism of action by which MNPs cause neurotoxicity |
| PMC11281156__F6 | Proposed cellular signal transduction pathway of TCBPA-induced cell inflammation in Jurkat cells |
| PMC11281541__F10 | Hypothetical schema of the protective role of MIN in TBEV-infected Vero cells |
| PMC11281550__F6 | Changes in metabolites in PI3K/AKT/FOXO signaling pathway after TeA, PAT alone, and combined exposure |
| PMC11281655__F2 | RIG-I-like receptor signaling pathway in antiviral immunity |
| PMC11281666__F9 | Deoxynivalenol and Its Acetylated Derivatives on Lipid Metabolism in Human Normal Hepatocytes |
| PMC11284386__F1 | Systemic and renal iron homeostasis |
| PMC11284857__F3 | Disturbance of DFC signaling pathways results in disorders of osteoclast differentiation |
| PMC11284857__F4 | Depicted regions primarily reside within the dental follicle tissue surrounding the root apex |
| PMC11287639__F1 | SMAD4 in the transforming growth factor-beta (TGFB) signalling pathway |
| PMC11292300__F2 | WNT signaling pathway in CMTC |
| PMC11292300__F4 | The rationale for possible targeted therapies in CMTC |
| PMC11292615__F0 | This review seeks to offer a comprehensive look at how salidroside impacts gut microbiota and its potential therapeutic role in treating atherosclerosis |
| PMC11294417__F10 | Schematic diagram for NEK2 functions during porcine embryonic development |
| PMC11294427__F2 | S100A9 binds to Toll‐like receptor 4 (TLR4) to activate downstream pathways for biological effects |
| PMC11294427__F3 | The S100A9‐receptor for advanced glycation end products (RAGE) signalling pathway in cardiovascular disease |
| PMC11302569__F3 | Four key mechanisms of gut microbiome associated with the occurrence and progression of colorectal cancer a |
| PMC11302868__F2 | Four main defense pathways in ferroptosis |
| PMC11302957__F1 | Core components of the Hippo pathway in mammals |
| PMC11302957__F3 | Crosstalk of Hippo signal pathway with other signaling pathways to regulate YAP1 |
| PMC11307123__F6 | Mechanism of diabetes promoting myocardial fibrosis via AMP-activated protein kinase (AMPK)/enhancer of zeste homolog 2 (EZH2)/peroxisome proliferator-activated receptor G (PPARG) signaling pathway |
| PMC11307883__F3 | Metabolic pathways of the microRNAs and their target genes |
| PMC11310285__F1 | Hypoxia signaling pathway |
| PMC11310285__F2 | Hypoxia pathway proteins-microRNA-phosphodiesterase crosstalk in steroidogenesis regulation |
| PMC11311281__F4 | PAR2-induced Beta-catenin stabilization and targets of RNF43 |
| PMC11311379__F9 | Regulatory effects of novel-m0230-3p on cell TJs and adhesion via CSF1/CSF1R/Ras signaling pathway in yak SCs |
| PMC11311387__F4 | Involvement of p53 in cell stress responses and glycosylation-related pathways and the relationship between p53 glycosylation and cancer progression |
| PMC11311579__F1 | Metabolic pathway of vitamin D and the role of VDR (Vitamin D Receptor) in signaling based on Płomiński et al |
| PMC11311808__F2 | Genetic and Signalling pathway dysregulation in AC |
| PMC11312265__F1 | Molecular mechanisms of inhibited and activated canonical Wnt/Beta-catenin signaling pathway |
| PMC11312265__F2 | Signaling cascade of non-canonical Wnt/PCP and Wnt/Ca2+ pathway |
| PMC11312265__F5 | Non-canonical Wnt/PCP and Wnt Ca2+ signaling and their implications in cancer |
| PMC11312279__F9 | Ceramide Ehux-C22 Targets the miR-199a-3p/mTOR Signaling Pathway to Regulate Melanosomal Autophagy in Mouse B16 Cells |
| PMC11312684__F1 | GSH synthesis and transport of precursor amino acids: (a) Gamma-Glutamyl cycle of GSH synthesis |
| PMC11312684__F2 | GPx4 in the ferroptosis regulatory pathway: (a) GPx4 catalytic cycle representation |
| PMC11312688__F2 | Radiation Induced Skin Fibrosis (RISF): Opportunity for Angiotensin II-Dependent Intervention |
| PMC11312688__F3 | Proposed Rearticulation of the Mechanism for Radiation-Induced Fibrosis: Initial radiation exposure initiates at least three distinct pathways |
| PMC11312736__F7 | Glycolysis/gluconeogenesis, pentose phosphate pathway, photosynthesis and sucrose and starch metabolism in zygotic embryos of Yucatan green dwarf and Mexican Pacific tall cultivars |
| PMC11312736__F8 | Saturated and unsaturated fatty acid metabolic pathways and mevalonate and isoprenoid biosynthesis at intermediate and mature stages of YGD and MPT zygotic embryos |
| PMC11313175__F2 | RNA methylation in the development of muscle and fat in livestock |
| PMC11313179__F7 | Illustration of the most significant regulated target genes related to PPAR signaling pathway |
| PMC11313500__F2 | Molecular pathway mechanisms of cytokines and chemokines associated with inflammation for the progression of pulmonary hypertension |
| PMC11313706__F6 | Regulatory mechanism of bone injuries induced by fluoride |
| PMC11314049__F5 | Schematic illustration of reactive oxygen species (ROS)-mediated activation of various cell signaling pathways in the skin |
| PMC11314424__F3 | Diagram summarizing the effects of salidroside (SAL) on cellular signaling pathways |
| PMC11314475__F5 | Investigating the Molecular Mechanisms of Resveratrol in Treating Cardiometabolic Multimorbidity: A Network Pharmacology and Bioinformatics Approach with Molecular Docking Validation |
| PMC11315658__F5 | Synergism between TMEM16A and EGFR in mediating the proliferation of tumors |
| PMC11316721__F1 | Molecular mechanisms of RBP4 in insulin resistance |
| PMC11316721__F2 | Molecular mechanisms of RBP4 in pancreatic Beta-cell function |
| PMC11317487__F0 | Graphical abstract and proposed pathway of rhMFGE8 administration attenuate hippocampal injury by improving neurogenesis in SAH models |
| PMC11324288__F1 | SLC44A2 mediates the VSMC phenotypic switch in aortic aneurysm |
| PMC11326265__F7 | The effect of miR-1 loss on glycolytic and pentose phosphate enzymes and intermediates |
| PMC11332896__F2 | Signaling pathways involved in muscle atrophy during cachexia |
| PMC1133795__F3 | Functions of NFKB1 and NFKB2 in immune cell biology |
| PMC11338244__F2 | Tamoxifen resistance |
| PMC11338244__F4 | Methylation of the PI3K/AKT/mTOR signaling pathway on tamoxifen |
| PMC1133850__F10 | Vaccinia virus-stimulated mitogen-activated protein kinase (MAPK) pathway is required for virus multiplication |
| PMC11343602__F8 | Schematic diagram illustrating the mechanism and intervention strategies of the IL-27/Blimp-1 axis in regulating Tim-3 expression on Tregs |
| PMC11347096__F2 | Phospholipids and their binding proteins mediate normal or malignant B cell activation |
| PMC11347096__F3 | Cholesterol metabolism is necessary to defend against foreign antigens |
| PMC11347096__F4 | Sphingolipid metabolism |
| PMC11347096__F5 | Schematic diagram summarizes the regulation of lipid metabolism in normal or malignant B cells |
| PMC11347096__F6 | Schematic diagram summarizes the potential therapeutic targets of different lipid species and related pathways to treat inflammatory disease or B cell malignancy |
| PMC1134761__F4 | Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit |
| PMC1134985__F3 | Exploring the functions of RNA interference pathway proteins: some functions are more RISCy than others? |
| PMC11350665__F7 | Main biological pathway responses to acute Cd exposure in oysters |
| PMC11350703__F18 | PDK1-mediated TGFB/Smad signaling pathway by hypoxia in yellow cattle and yak PASMCs |
| PMC11351389__F2 | Mechanistic Insights and Therapeutic Strategies in Osteoporosis: A Comprehensive Review |
| PMC11351389__F3 | Mechanistic Insights and Therapeutic Strategies in Osteoporosis: A Comprehensive Review |
| PMC11351392__F3 | Targeting the Nrf2/HO-1 axis for the treatment of IBD |
| PMC11351413__F2 | Biosynthetic pathway of cordycepin |
| PMC11351628__F1 | PPAR targets and contributing factors in MASLD/MASH |
| PMC11351691__F4 | Hub proteins were obtained and verified by molecular docking |
| PMC11351712__F7 | Graphical abstract |
| PMC11351910__F3 | PI3K/AKT signaling pathway and miRNAs in pancreatic cancer |
| PMC11351910__F4 | KRAS signaling pathway and miRNAs in pancreatic cancer |
| PMC11351910__F5 | JAK/STAT signaling pathway and miRNAs in pancreatic cancer |
| PMC11351910__F6 | TGFB signaling pathway and miRNAs in pancreatic cancer |
| PMC11351910__F7 | Wnt/Beta-Catenin signaling pathway and miRNAs in pancreatic cancer |
| PMC11352233__F7 | HER2/epidermal growth factor receptor (EGFR) signalling pathway in breast cancer |
| PMC11352355__F2 | Cell functions of K6, K16, and K17 |
| PMC11352684__F4 | TRIM proteins in the cellular signaling pathway of MAFLD |
| PMC11352841__F1 | Bacterial induced mastitis via activating TLR2/TLR4/NFKB signaling pathways in mammary gland cells |
| PMC11352841__F2 | Bioactive compounds targeting NFKB signaling pathway to prevent inflammatory changes and mastitis |
| PMC11352841__F3 | Probiotic targetingTLR2/TLR4 /NFKB signaling pathway to prevent inflammatory changes and mastitis |
| PMC11352994__F7 | Schematic overview of the B7-H4-mediated signalling pathway in trophoblast cells in patients with early-onset PE |
| PMC11353016__F2 | Molecular drivers regulating hair follicle fate specification and the initiation of its growth |
| PMC11353125__F1 | Receptor tyrosine kinases (RTKs), epidermal growth factor receptor (EGFR), and its variant EGFRvIII activate the PI3K/AKT signaling pathway, subsequently influencing mTOR activity |
| PMC11353167__F1 | FCERI signaling pathway |
| PMC11353167__F2 | MAPK signaling pathway |
| PMC11353192__F7 | Lactate and LOX regulation of the HCAR1-RAS/PI3K signaling cascades |
| PMC11354414__F3 | Cell signaling pathway involving TNFA in activating NFKB |
| PMC11354507__F1 | SARS-CoV-2 entry, mitochondrial damage sensing and innate immune dysregulation |
| PMC11354507__F2 | Inflammation triggered by macrophage after SARS-CoV-2 infection |
| PMC11354542__F6 | Neurotrophin-signaling pathways in the high-intensity exercise group (blue: downregulation) |
| PMC11354572__F1 | Serum TLR2 and TLR9 in Prostate Cancer Patients in Relation to EBV Status |
| PMC11354614__F2 | Glucose and stress metabolism |
| PMC11354688__F5 | Process of human steroidogenesis |
| PMC11354764__F1 | Insulin signaling pathway |
| PMC11354764__F2 | Main pathways involved in the development of insulin resistance |
| PMC11354764__F3 | Three main UPR pathways induced by ER stress |
| PMC11354767__F6 | GPR30 signaling pathway |
| PMC11354818__F12 | Integrative Analyses Reveal the Physiological and Molecular Role of Prohexadione Calcium in Regulating Salt Tolerance in Rice |
| PMC11354818__F14 | Integrative Analyses Reveal the Physiological and Molecular Role of Prohexadione Calcium in Regulating Salt Tolerance in Rice |
| PMC11354872__F2 | Short chain fatty acids (SCFAs) and antioxidant roles against CRC development |
| PMC11355043__F1 | Current model of the blood coagulation cascade, depicting NOACs’ mechanism of action |
| PMC11355432__F7 | Proposed model for the protective mechanism of CPE against CKD-induced HAS |
| PMC11355545__F8 | Schematic depicting the signaling pathway ROS/PARP/TRPM2 that causes SiNPs-induced lung inflammation in mice |
| PMC11356322__F3 | Metabolic pathway interaction network of Cluster-0 metabolite (4-hydroxybenzoic acid) |
| PMC11356641__F4 | Signaling pathway involved in probiotics recognition |
| PMC11356816__F9 | Interactions between BAs and Other Viruses |
| PMC11356869__F1 | Signaling pathways in osteogenesis and osteoclastogenesis |
| PMC11356869__F2 | East Asian Herbal Medicine (EAHM) effect on bone to prevent osteoporosis |
| PMC11356883__F4 | Outline of the DTSAs biosynthetic pathway in Dendrobium species |
| PMC11356930__F2 | MEHTCMPs on the signaling pathway of TLRs |
| PMC11356930__F3 | MEHTCMPs on the MAPK signaling pathway |
| PMC11356930__F4 | MEHTCMPs on the NLRP3 signaling pathway |
| PMC11356930__F5 | MEHTCMPs on intestinal flora |
| PMC11357136__F2 | Several modulator molecules linked to the signaling of GLP-1 receptor within the PI3K/AKT/mTOR pathway are demonstrated |
| PMC11357158__F1 | Biological pathways and interactions of three ncRNAs |
| PMC11357158__F2 | TGFB1/Smad pathway mediated by identified ncRNAs |
| PMC11357158__F3 | Hippo and Hedgehog pathways mediated by identified ncRNAs |
| PMC11357158__F5 | Wnt/Beta-catenin pathway and associated ncRNAs |
| PMC11357207__F4 | Working model to propose ABC-transporter mediated cholesterol efflux reduces the pro-inflammatory immune response that initially occurs from T |
| PMC11357267__F3 | Pathways altered in chickens vaccinated with GII |
| PMC11357512__F2 | Signalling pathway in a cardiomyocyte with lamin A/C variant factors such as pERK1/2, pSmad1/2, and TEAD1 affect the gene expression of LMNA mutant cells |
| PMC11359136__F2 | HCMV regulates the classical Wnt/Beta-catenin signaling pathway |
| PMC11359136__F3 | HCMV regulates the Notch signaling pathway |
| PMC11360076__F4 | Protein–protein interaction map of the upstream regulators that significantly altered after the exposure to V |
| PMC11360082__F2 | Catechol estrogens synthesis pathway in humans and the possible homologs identified in schistosome species |
| PMC11360101__F13 | Actin Dysregulation Mediates Nephrotoxicity of Cassiae Semen Aqueous Extracts |
| PMC11360101__F7 | Cytoscape shows the interactions between 9 major components of CSAEs and 4 known kidney injury pathways |
| PMC11361845__F5 | Analysis of changes in the proteome and phosphoproteome according to DNK72 treatment in patient derived glioblastoma cells |
| PMC11361850__F3 | Mechanism by which mesenchymal stem cells-derived exosomes (MSCs-Exos) regulate the immune response |
| PMC11361850__F5 | Mechanism by which mesenchymal stem cells-derived exosomes (MSCs-Exos) regulates apoptosis and autophagy |
| PMC11361850__F6 | Mechanism by which mesenchymal stem cells-derived exosomes (MSCs-Exos) promotes axonal growth and neuronal regeneration |
| PMC11364386__F1 | Blockade of secretory vesicle biogenesis provides a therapeutic strategy for targeting cancer |
| PMC1140402__F2 | The central carbon metabolism of E |
| PMC1140591__F7 | Signaling model for hypoxic activation of HIF-1 |
| PMC1140638__F8 | Proposed model of Tiam1 and IRSp53 signaling |
| PMC1143566__F2 | A schematic diagram for the hedgehog (HH) signaling pathway |
| PMC1143566__F4 | Schematic diagram for the Wnt signaling pathway |
| PMC114459__F1 | Mechanisms of ISG induction |
| PMC115962__F5 | IFNG signaling pathway showing the defects in the human fibroblast mutants B3, B9, and B10 |
| PMC1160519__F6 | Cardiac glycosides inhibit TNFA/NFKB signaling by blocking recruitment of TRADD to the TNFR |
| PMC116060__F6 | Proposed signal transduction pathways involved in PKC-mediated SRE activation |
| PMC1168613__F1 | Comparison of the D |
| PMC1168814__F8 | The regulation of replication-dependent histone H4 genes at the G1/S phase cell cycle transition via the cyclin E/CDK2/p220/HiNF-P pathway relative to the E2F/pRB pathway |
| PMC1169236__F2 | Metabolic reconstructions of the polyamine pathway based upon pam and sam analyses of poor-prognosis human NE tumors |
| PMC1172066__F8 | Model depicting how inner ear polarity is generated in response to extracellular signals |
| PMC1173149__F10 | TAp63Alpha-induced apoptosis |
| PMC1174965__F4 | Regulation of lipopolysaccharide (LPS) signaling by suppressor of cytokine signaling 1 (SOCS1) |
| PMC1175050__F1 | NFKB pathway regulates inflammation, dendritic cell (DC) development and function, and thymic selection and regulatory T cell production |
| PMC1176393__F2 | Regulatory network of stress responses to drought, salt, and cold: specificity and cross-talk |
| PMC1176468__F9 | Crosstalk model of ATF3 and c-myc in serum induction |
| PMC118037__F6 | Model depicting direct and indirect regulation of clock output genes involved in conidiation |
| PMC1180390__F5 | Signaling pathways implicating p120-RasGAP |
| PMC1183194__F4 | Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin |
| PMC1183194__F5 | Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin |
| PMC1183194__F6 | Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin |
| PMC1183420__F1 | Simplified 13-hydroxylation pathway of GA biosynthesis in vegetative tissue of pea |
| PMC1183479__F8 | Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2) |
| PMC1186689__F1 | Interferon-Gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes |
| PMC1186734__F6 | Glucocorticoid Receptor-Dependent Gene Regulatory Networks |
| PMC1190322__F10 | CdGAP mediates cross talk between the Ras/MAPK pathway and the regulation of Rac1 activity |
| PMC1190355__F8 | A model of IRAK1c regulation of inflammation |
| PMC1193534__F1 | Comparative Genomics of Natural Killer Cell Receptor Gene Clusters |
| PMC1193608__F8 | Model of HAV interaction with the dsRNA-induced IRF-3 activation pathway |
| PMC1195384__F2 | Folate pathway in Plasmodium falciparum and the proposed mode of action of the diaminopteridines, analogs of folate precursors |
| PMC1195968__F1 | RSV binding and triggering of cellular responses |
| PMC1197416__F6 | Several signaling pathways converge to drive actin polarization |
| PMC1199368__F5 | Candidate genes that are involved with the metabolism of androgen and estrogen |
| PMC1201250__F7 | Mechanism of TgHSP70 tolerance in PMs from WT mice |
| PMC1201344__F4 | Fasting effects on fatty acid composition |
| PMC1201361__F6 | Anandamide as an intracellular messenger inducing Ca2+ influx via TRPV1 |
| PMC1201394__F4 | Cell Cycle Arrest and Cell Death Are Controlled by p53-dependent and p53-independent Mechanisms in Tsg101-deficient Cells |
| PMC1201514__F1 | Regulation of the PIS1-encoded Phosphatidylinositol Synthase in Saccharomyces cerevisiae by Zinc |
| PMC120783__F7 | GPI biosynthetic pathways in T |
| PMC120784__F11 | Upper part of the glycolytic pathway and pathways for production of glycerol, trehalose, and glycogen, with all proteins and their isoforms indicated |
| PMC120784__F8 | Outline of the cell integrity pathway |
| PMC1215521__F7 | Possible gene regulation in macrophage THP-1 stimulated by theophylline |
| PMC1216340__F10 | Schematic model depicting potential mechanism that might contribute to epithelial-specific regulation of the CFTR gene |
| PMC122866__F4 | The pathway of PUFA synthesis in C |
| PMC1234333__F7 | Knockdown of Smad4 affects only a subset of TGF-Beta-regulated target genes and functions |
| PMC1235815__F7 | Possible ATM pathways contributing to polyomavirus replication (see Discussion) |
| PMC1236692__F3 | Caspase signaling and its modulation |
| PMC1236696__F1 | IKK/NFKB signaling pathways |
| PMC1236698__F2 | Molecular mechanisms of autophagy |
| PMC1236700__F2 | Regulation of the extrinsic pathway by Hsps |
| PMC123677__F3 | The action of S-phase checkpoints in the suppression of spontaneous genome instability |
| PMC1237009__F1 | Will the Real Cholesterol Transporter Please Stand Up |
| PMC1237076__F7 | Wnt-NLK pathway inhibits the activity of Myb family of proteins by two different mechanisms |
| PMC125566__F1a | Negative regulation of the Wnt–Beta-catenin pathway by the transcriptional repressor HBP1 |
| PMC125566__F7 | Negative regulation of the Wnt–Beta-catenin pathway by the transcriptional repressor HBP1 |
| PMC125938__F8 | An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype |
| PMC126023__F7 | Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae |
| PMC126171__F5 | Different telomere damage signaling pathways in human and mouse cells |
| PMC1262766__F1 | The kynuric pathway of melatonin metabolism |
| PMC1262773__F4 | Endocrine regulation of the testis |
| PMC1265881__F1 | An integrated model of signal transduction via the AT1R and resultant physiologic effects within the cardiovascular system |
| PMC1280267__F7 | Model schema for the phosphorylation of CRMP-2 by Rho kinase, Cdk5, and GSK-3B |
| PMC128142__F1 | Proposed biosynthetic pathway of GPI in the ER of P |
| PMC1287678__F9 | Putative signaling pathway of the evolutionarily conserved Toll/NFKB pathway utilizing the E |
| PMC1287992__F6 | Induction of cell death by NO-ASA |
| PMC1288263__F2 | Mammalian sex determination: a molecular view |
| PMC1288546__F1 | Human SHH-PTCH-GLI pathway (left) and its links to human diseases (right) |
| PMC128926__F2 | Activation of the NFKB pathway by IL-1 |
| PMC1297264__F3 | Interaction of the Wnt, BMP, and sclerostin pathways |
| PMC129737__F5 | Model for repair of camptothecin-induced replicative damage |
| PMC1297571__F6 | Simplified diagram of the proposed signalling events leading to Cyp7b gene transcription in synovial fibroblasts |
| PMC1297590__F2 | Ubiquitination of key signaling in anergic T cells |
| PMC1297640__F1 | Systems and molecular complexity in glycobiology |
| PMC1297683__F3 | Final network resulting from applications of our integration method to the 18 types of evidence for yeast galactose utilization and a set of network analysis tools |
| PMC1304358__F3 | Examples of extreme signaling pathways of the JAK-STAT signaling network |
| PMC1304643__F2 | Probability flux distributions for human red blood cell |
| PMC1312313__F8 | NO• regulation of the cell cycle |
| PMC1315804__F1 | NFKB signalling pathways in different cell systems |
| PMC1315902__F2 | Multiple roles for kinases in DNA replication |
| PMC1316260__F6 | Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway |
| PMC1317640__F9 | GA12-mediated activation of PDGFRA signaling pathway |
| PMC1322299__F1 | Tweaking Microtubules to Treat Scleroderma |
| PMC1323499__F1 | New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor |
| PMC1326326__F3 | Proposed regulation of Cdc25A at the G1 and intra-S-phase checkpoints |
| PMC1327675__F3 | Interactive map (pathway) of 46 genes/proteins created in PathwayAssist® from the list of transcripts up-regulated in the testes of ABP-transgenic mice |
| PMC1327682__F3 | Schematic overview of the Saccharomyces cerevisiae central carbon metabolism |
| PMC133602__F6 | The yeast glyoxylate bypass pathway and its possible connection with other predicted changes |
| PMC134648__F8 | Role of Axin2 in Wnt signal transduction |
| PMC1350949__F7 | Proposed model of the HCMV-induced apoptotic signaling pathways |
| PMC1351030__F8 | Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. |
| PMC1351175__F11 | Proposed Receptor Ck - dependent signaling pathway involved in hTERT gene regulation at the transcriptional level |
| PMC1351245__F1 | Delayed Dark Adaptation in 11-cis-Retinol Dehydrogenase-deficient Mice |
| PMC1356091__F4 | Signal Processing in the TGFB Superfamily Ligand-Receptor Network |
| PMC1356334__F7 | Alignment of sequences adjacent to Y200 for human TRPV1-4 |
| PMC1359062__F1 | Ciliated cell differentiation into goblet cells requires 2 signals |
| PMC1360652__F6 | Working model for the effects of 15d-PGJ2 and thiazolidinediones on TNF-stimulated NFKB activation and COX2 expression |
| PMC1361319__F1 | Scheme of branch pathways of phenylpropanoid metabolism in plants leading to the synthesis of anthocyanins, flavonols, PAs, and lignin |
| PMC1361361__F7 | Shp-1 mediates the anti-proliferative activity of TIMP-2 in human microvascular endothelial cells |
| PMC136456__F7 | The modulation of cellular signaling pathways by NS5A |
| PMC1369209__F3 | Models for ECT-2 activation and its role in activating the EGFR/RAS/MAPK pathway |
| PMC137069__F1 | Hh-signaling pathway |
| PMC1371031__F4 | Model on Bcr effects on Beta-catenin |
| PMC137498__F6 | Regulation of Cdc25A by Chk1 |
| PMC1375233__F2 | Association between human TLRs and adaptors determine each TLR-specific signaling pathway |
| PMC1375233__F5 | Two signaling pathways of TLR in myeloid DCs |
| PMC1380241__F1 | CoQ10biosynthetic pathway with eight known biosynthetic enzymes denoted as COQ1-COQ8 |
| PMC1383482__F1 | Tumor Necrosis Factor by Microbial Pathogens |
| PMC1383515__F6 | Proposed tentative mechanism underlying MAFA-mediated selective inhibition of FcɛRI-induced cytokine gene transcription |
| PMC1383550__F2 | Two branches of the class I PI3K pathway |
| PMC1383660__F5 | Intracellular signalling pathways activated by leptin |
| PMC1383660__F6 | Intracellular signalling pathways activated by leptin |
| PMC1386115__F3 | Integration of lipid metabolic and inflammatory signaling in macrophages by LXRs |
| PMC1386711__F4 | MAPK signaling pathway mapping |
| PMC138687__F1 | The TGFB signaling pathway, showing the activation cascade and points of inhibition (??) |
| PMC138693__F2 | Phosphoinositide 3-kinase (PI3K) signalling and cancer |
| PMC138699__F1 | Simplified diagram of the canonical Wnt/Beta-catenin signaling pathway |
| PMC138773__F1 | EGFR transactivation by GPCRs and cytokine receptors |
| PMC138773__F2 | Triple membrane-passing signal mechanism of EGFR transactivation |
| PMC138838__F1 | Signaling through mammalian and Drosophila Toll-family receptors (TLRs) |
| PMC1389768__F1 | The Challenge of Characterizing Operations in the Mechanisms Underlying Behavior |
| PMC139100__F8 | Gelsolin-induced epithelial cell invasion is dependent on Ras-Rac signaling |
| PMC139401__F2 | TLR signal transduction pathways |
| PMC139432__F1 | Transforming growth factor (TGF)Beta-induced growth inhibition |
| PMC139433__F2 | Cell cycle arrest by transforming growth factor (TGF)B and their deregulation in cancer |
| PMC1395315__F1 | Methionine-Homocysteine metabolism and related pathways |
| PMC1395315__F5 | Elevated Homocysteine is associated with atherosclerosis |
| PMC1397816__F1 | Inhibition of canonical Wnt signalling pathway in the absence of Wnt signals |
| PMC1397816__F2 | Activation of canonical Wnt signalling pathway in the presence of Wnt signals |
| PMC1397816__F5 | Inhibition of Wnt signalling by a Fz-dependent pathway |
| PMC139817__F7 | Regulatory interactions between SRF and TCF |
| PMC139865__F12 | Innate immunity pathways in Drosophila |
| PMC140043__F8 | RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF |
| PMC140098__F7 | A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer |
| PMC140192__F7 | Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF |
| PMC140507__F1 | The PI 3-kinase pathway by RNAi |
| PMC140665__F8 | Interaction between the Wnt/Beta-catenin and Wnt/Ca2+ pathways |
| PMC1409799__F4 | MAPK signaling pathways |
| PMC1410736__F1 | Disposition of 17Beta-estradiol (E2) and metabolites |
| PMC1410746__F3 | Genmapp view of the epidermal growth factor (EGF) signaling pathway |
| PMC1410804__F7 | Cdc42 regulates HF differentiation and cell-cell contacts in keratinocytes by modulating the turnover of Beta-catenin and plakoglobin |
| PMC1413672__F6 | Activation of PI3K signaling by PV |
| PMC1413813__F8 | The signaling pathway regulating the expressions of SMAlpha-actin, SM-MHC, and calponin in SMCs on polymerized collagen in response to PDGF-BB/IL-1B costimulation |
| PMC1415320__F6 | The proposed TGFB1 signaling mechanism that promotes EMT |
| PMC1420312__F5 | Impact of SV40 ST on the Notch, Wnt, and Hedgehog Pathways |
| PMC1421301__F1 | Interferon Regulatory Factor Expression in Human Breast Cancer |
| PMC1421310__F1 | High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells |
| PMC1431703__F5 | Comparison of results with the known response pathway |
| PMC1431720__F7 | Cytokine release in RAW 264.7 macrophages |
| PMC1431720__F8 | Combined network of signaling components required for the production of cytokines |
| PMC1434604__F1 | Sites of action for reactive oxygen species in the regulation of the insulin signaling pathway |
| PMC1435694__F1 | Chemistry of the retinoid cycle reactions in the vertebrate retina |
| PMC1435944__F6 | Graphical Interface for the KnowledgeNet of candidate genes for hypertension |
| PMC1436016__F7 | The JNK pathway promotes and maintains mitosis until the mitotic-to-endocycle transition point |
| PMC1436036__F12 | Core signaling pathway downstream from V2R occupation in IMCD |
| PMC1440308__F6 | Alternative Th network |
| PMC1440308__F7 | Alternative Th network |
| PMC1440398__F2 | CDC maturation upon virus infection |
| PMC1440856__F1 | Omega-6 and -3 fatty acids & Prostate Cancer |
| PMC1446957__F5 | In vitro keratinocyte mitosis |
| PMC1447421__F10 | Hypothetical model describing the roles of Rad18 and PolK in the BPDE-induced S-phase checkpoint |
| PMC1448211__F7 | Real time pathway analysis of cell-cycle related genes mediated via TS overexpression in HCT-C18 (TS+) cells using actual gene expression data |
| PMC1449579__F1 | F igure 1.— |
| PMC1449579__F5 | F igure 5.– |
| PMC1449730__F2 | F igure 2.— |
| PMC1450137__F4 | Proposed mechanisms underlying the control of Mesp2 expression |
| PMC1456930__F5 | The molecular pathways controlling AB generation during aging |
| PMC1456973__F6 | Aspartate and aspartate transport in the pathway of prostate citrate production |
| PMC1458968__F4 | Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin |
| PMC1464269__F1 | Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies |
| PMC1475580__F1 | Sequence of events in ATM→ATR dependent signaling of DSBs in S/G2 cells |
| PMC1475884__F2 | TNF receptor (TNFR) pathway of signaling |
| PMC1479092__F1 | The mitochondrial generated ROS-mediated activation of the p38 MAPK stress response pathway |
| PMC1479345__F3 | Pathway analysis |
| PMC1479345__F4 | Pathway analysis |
| PMC1479345__F5 | How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome. |
| PMC1479345__F6 | Pathway analysis |
| PMC1479345__F7 | Pathway analysis |
| PMC1479816__F3 | Pathways involved in mesenchymal cell proliferation and differentiation induced by G protein coupled receptors (GPCRs) |
| PMC1480427__F1 | ω3 LC-PUFA and ω6 LC-PUFA biosynthetic pathways |
| PMC1480599__F7 | Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response |
| PMC1481516__F2 | Metabolic pathway and bioenergetics of net citrate production in prostate cells |
| PMC1481658__F11 | Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity |
| PMC1482580__F4 | EDA signaling in hair follicle development |
| PMC1482699__F5 | GenMAPP growth hormone (Gh) signaling pathway |
| PMC1483059__F10 | Peculiar structure of the juxtanuclear actin network |
| PMC1483149__F1 | Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony |
| PMC1483167__F1 | Liver X receptor opens a new gateway to StAR and to steroid hormones |
| PMC1487177__F7 | AKT-1/PKB Signaling |
| PMC1489534__F3 | Regulation of cell wall gene expression during the cell cycle (A) and in response to external stimuli (B) |
| PMC14940__F10 | A signaling pathway of c-Met for cell scattering |
| PMC149906__F5 | A model to explain the effects of varying Fgf8 dosage on cell survival |
| PMC1501017__F2 | Different pathways involved in apoptosis |
| PMC1501125__F1 | WNT Pathway in Colorectal Carcinomas Stratified by Microsatellite Instability |
| PMC1502028__F4 | EGFR and mTOR signaling network, and signaling mediator effects associated with rapamycin and/or EKI-785 treatments |
| PMC1502396__F1 | The interaction between the AR and the ErbB/MAPK pathway |
| PMC1502426__F1 | Chromophore regeneration in vertebrate and invertebrate photoreceptors |
| PMC1502453__F5 | Hoxc8-regulated transcriptional network in vivo |
| PMC1502529__F6 | Network modeling |
| PMC1502564__F3 | Model diagrams indicating regulation and function of E47 activity |
| PMC150381__F2 | Interplay of the major genetic alteration in pancreatic carcinoma with the cell cycle |
| PMC150458__F3 | Known Wnt signaling pathways |
| PMC1507568__F3 | The p53 response is triggered by many different stresses involving both DNA-damaging and non-DNA-damaging agents |
| PMC1508148__F1 | Pathway diagram of genes tested for association |
| PMC150988__F1 | JAK-STAT signaling and the generation of Th1 and Th2 cells |
| PMC151039__F1 | The classical pathway for bile acid synthesis begins with CYP7A1, which converts cholesterol into 7Alpha-hydroxycholesterol |
| PMC151063__F9 | p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop |
| PMC151138__F1 | Signaling and transcriptional pathways of Th1 differentiation and the potential role of c-Rel |
| PMC151300__F2 | Model of the S |
| PMC151358__F5 | JNK-dependent apoptosis signaling pathway |
| PMC151800__F1 | Putative interactions between relaxin receptor signaling and intrinsic NO pathway |
| PMC151822__F2 | Signaling UPR-mediated cell death |
| PMC1522081__F7 | Involvement of MACF1 in the Wnt/Beta-catenin signaling pathway |
| PMC152295__F1 | The PI metabolic pathway and wortmannin sensitivity |
| PMC1525002__F4 | Sequence logo [41] of putative regulatory motif |
| PMC1525228__F9 | Diagram depicting the mechanism by which NGF may inhibit GSK-3B and promote axon growth |
| PMC1525234__F6 | Working model of regulatory mechanisms controlling cell death in response to mating pheromones |
| PMC1526464__F8 | Bile acid and cytokine inhibition of CYP7A1 gene transcription |
| PMC1526532__F1 | Genomic Analysis of the Opi- Phenotype |
| PMC1526546__F1 | Innate model of lupus pathogenesis: central role of TLR-activated MZ-B cells and pDCs |
| PMC1526596__F1 | P38 mitogen-activated protein kinase (MAPK) signaling cascade in T cells |
| PMC1526619__F1 | Wnt/Beta-catenin signaling pathway |
| PMC1526619__F2 | The canonical transforming growth factor (TGF)B/Smad signaling pathway |
| PMC152905__F6 | Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line |
| PMC1531665__F4 | TGFB1-induced Erk activation and EMT being blocked by U0126 |
| PMC1533821__F2 | Recognition of pathogens by cytosolic PRRs |
| PMC153558__F3 | Model of the maternal Radar signaling pathway mediating early steps of dorsoventral axis formation |
| PMC153613__F4 | Highlights of key changes in cell cycle, differentiation, and metabolism-related transcripts |
| PMC1538848__F3 | Expression data analysis and visualization on the PANTHER website |
| PMC154144__F2 | Canonic Wnt signaling pathway molecules can induce a similar phenotype |
| PMC154424__F3 | Schematic showing the mevalonate pathway |
| PMC1550314__F1 | Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells |
| PMC1551980__F1 | Ubiquitin Signaling in the NFKB Pathway |
| PMC1551980__F3 | Ubiquitin Signaling in the NFKB Pathway |
| PMC1551980__F4 | Ubiquitin Signaling in the NFKB Pathway |
| PMC155294__F4 | Representation of the cell cycle control pathway within TIGR Orthologous Gene Alignment (TOGA) |
| PMC1553197__F8 | Model of CISK-mediated inhibition of CXCR4 sorting and degradation |
| PMC155330__F7 | slpr, encoding Drosophila MLK, is the MKKK for the Jun kinase pathway during dorsal closure in the fly |
| PMC1553448__F7 | Transcript expression of BMP signaling pathway members |
| PMC155355__F7 | Model outlining the roles of GAI/RGA-like GA-signaling components in the plant life cycle |
| PMC155392__F3 | Predicted pathways for degradation, transport, and metabolism of chitin by M |
| PMC1555658__F2 | Cholesterol precursors and facial clefting |
| PMC155638__F1 | MAP kinase signalling pathways |
| PMC155638__F3 | Hypoxic activation of apoptosis pathways |
| PMC1557712__F2 | Molecular control of alveolar morphogenesis |
| PMC1557825__F4 | Ordering and correlation network diagrams for the significant pathways |
| PMC1559555__F1 | GSH metabolic pathway |
| PMC1559676__F1 | The unfolded protein response |
| PMC1560089__F7 | Proposed LITAF signaling pathway |
| PMC1560097__F3 | Light-cycle of rhodopsin |
| PMC156240__F1 | Xu-5-P is the signal for the coordinated control of lipogenesis |
| PMC1564158__F2 | Predicting Essential Components of Signal Transduction Networks: A Dynamic Model of Guard Cell Abscisic Acid Signaling |
| PMC1564204__F6 | Schematic pathway of lipid turnover induced by Pi stress |
| PMC156758__F1 | NEW EMBO MEMBER'S REVIEW |
| PMC156764__F1 | NEW EMBO MEMBER'S REVIEW |
| PMC1569532__F1 | Different types of regulatory T cells |
| PMC1570177__F1 | Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability |
| PMC1571066__F2 | TGFB superfamily signalling pathway (see text for explanation) |
| PMC1571066__F5 | Model of SMAD7 role in control of blood vessel calibre (see text for explanation) |
| PMC1571327__F6 | FGF, Wnt and Tbx3 in epithelial-mesenchymal interactions regulating mammary gland initiation |
| PMC1572165__F3 | Schematic drawing that shows the importance of cell-to-cell and cell-to-matrix-interactions in endothelial cell survival |
| PMC1573858__F1 | AT1 receptor signal transduction pathways that result in transcriptional NA neuromodulation (a) and increased firing rate (b) in neuronal cultures |
| PMC1574111__F3 | Proposed mechanism for FK506-potentiated neurite outgrowth |
| PMC1579207__F3 | Cadmium-induced regulation of SCFMet30 |
| PMC1584297__F9 | Cross-talk between the NFKB and the STAT3 pathways |
| PMC15871__F3 | PI3'K signaling modules in mammals and nematodes have implications for cancer |
| PMC1592599__F1 | TNFA signaling pathway leading to apoptosis or proliferation of the cells |
| PMC1592643__F3 | An altered balance of proapoptotic and antiapoptotic molecules in trauma patients' T cells could indicate specifically increased vulnerability to apoptotic depletion |
| PMC1594921__F5 | Presymptomatic and symptomatic infections including the inflammatory cytokines TNFA, IFNG, and ILB |
| PMC1594921__F6 | Immunological regulatory IL-10 and MAP kinase pathways |
| PMC15973__F7 | c-Src and PDGFR are connected functionally to each other and provide links to cell-cycle regulators in Gq-coupled 5-HT2B receptor mitogenic signaling |
| PMC1599906__F3 | TGFB signaling pathway |
| PMC1599931__F1 | Phosphatidylinositide 3'-OH kinase/Akt/mTOR signaling pathway |
| PMC1600679__F7 | Summary of changes in the Wnt/Beta-catenin pathway in pancreatic adenocarcinoma |
| PMC1601944__F1 | HIF-dependent VHL pathways in oncogenesis |
| PMC1601945__F1 | Model of RNF11 interactions in the TGFB receptor signaling pathway |
| PMC1601946__F1 | E3 ubiquitin ligases regulating the TGFB signaling pathway |
| PMC1602337__F9 | TWEAK-Fn14 signaling system may play a role in stroke pathophysiology |
| PMC1603434__F6 | TSC1/TSC2 in the canonical Beta-catenin signaling pathway |
| PMC1603666__F9 | Erk- and PI3K-Akt-dependent cascades regulating mTOR signaling |
| PMC1609106__F8 | Regulation of insulin pathway phenotypes by AKT-1 and PDK-1 activation |
| PMC1609340__F1 | Outline of the TLR signalling pathway |
| PMC1617297__F2 | Cell-signaling networks induced by Pichinde virus infection as analyzed using the Ingenuity pathway analysis knowledge base |
| PMC1618798__F2 | Intrinsic apoptotic signaling pathway |
| PMC1618798__F3 | Extrinsic apoptotic signaling pathway |
| PMC1622797__F5 | Proposed molecular model of dietary omega-3 fatty acid interference with IL-1 signaling pathways leading to COX-2 induction in EC |
| PMC1622889__F1 | Anti-apoptosis of families of HSPs |
| PMC1635984__F3 | MRNA expression levels in TGFBeta-treated T84 epithelial cells compared to control cell culture |
| PMC1636614__F8 | Schema of Ang II-induced NFAT activation in cardiac myocytes |
| PMC1636619__F8 | Oncogene cooperation in malignant rasV12, scrib-/- tumors |
| PMC1636849__F8 | Schematic summary of the signaling pathway leading to Nanog repression |
| PMC164216__F5 | TLR signaling pathways |
| PMC165090__F8 | Schematic model for the roles of p120 catenin in the signaling pathways leading to growth factor-induced RhoA stimulation and cell migration |
| PMC16561__F6 | The signaling pathway from the upstream protein-tyrosine kinases, Lyn/Syk/Btk, to cytokine gene expression through intermediate signaling proteins, PKCBI/JNK |
| PMC1664647__F1 | Schematic representation of the Fas pathway used in the mechanistic model |
| PMC1664664__F2 | Neurotrophin signalling |
| PMC1664665__F2 | Regulation of the axon cytoskeleton by PI3K signalling |
| PMC1664665__F3 | ECM-integrin signalling coordinates with growth factor signalling to regulate efficient axon growth |
| PMC1665458__F7 | Proteins differentially regulated in RCC involved in carbohydrate metabolism are shown overlaid on the glycolysis and gluconeogenesis pathway KEGG #00010 diagram |
| PMC1667087__F9 | F igure 9.– |
| PMC166813__F1 | The GA biosynthetic pathway in pea |
| PMC1679905__F6 | Signalling routes emanating from the epidermal growth factor receptor (EGFR) |
| PMC1681468__F5 | Ellipsis in drawing association states of proteins using an 'address' |
| PMC1681468__F6 | Combinations of multiple states of complexes |
| PMC1681473__F1b | (B) The bow-tie architecture also exists at the signal transduction level |
| PMC1681476__F1 | An SBGN process diagram (A) and a molecular interaction map (B) of a signaling pathway triggered by ligand binding to EGFR molecules |
| PMC1682009__F1 | Activation of the Akt pathway through binding of a ligand to a receptor, tyrosine kinase |
| PMC1682015__F2 | Example pathway structures based on Z-scores of reactions, which demonstrate the metabolomic response of the selected reactions in the reported case studies, namely, the effect of an altered redox metabolism and aerobic/anaerobic growth |
| PMC1682017__F4 | Effect of increased HER2 expression on phosphorylation sites within the EGFR signaling network |
| PMC1682017__F5 | Effect of HRG stimulation versus EGF stimulation in high HER2-expressing cells |
| PMC1683566__F5 | Integration of gene expression with the proposed mechanistic pathway initiated by comfrey treatment leading to tumorigenesis |
| PMC1698511__F3 | PKR is an intermediary component in TLR signaling |
| PMC1698524__F5 | Model linking HSP70 induction to p33ING1b-induced apoptosis |
| PMC1698527__F10 | Model for the transduction of DNA damage signals to the splicing machinery |
| PMC1698636__F6 | F igure 6.– |
| PMC1698952__F4 | Aspects of PRLR signaling as related to mammary gland function |
| PMC1705513__F1 | Inflammatory pathway in psoriasis |
| PMC1705980__F2 | Schematic model of autophagic regulation |
| PMC171388__F7 | Model of Cripto’s inhibition of Act B signaling through the Smad2 pathway |
| PMC1716201__F1 | Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737 |
| PMC1716221__F1 | Dominant role for glucose in B cell compensation of insulin resistance |
| PMC1728094__F1 | The receptor for IL-6 consists of the ligand binding component (IL-6R) and the signal-transducing gp130 |
| PMC17314__F1 | An integrated view of the biology of Halobacterium NRC-1 |
| PMC1751079__F1 | Inhibitory signals of the Toll-like receptor (TLR)4-induced MyD88-dependent signaling pathway |
| PMC1751493__F2 | In normal prostate epithelial cells (a), TGFB binds to the TBRI and TBRII receptors, activating the SMAD signalling pathway and inducing the transcription of IGFBP-3 and other regulatory genes |
| PMC1754372__F2 | Th1- and Th2-like lymphocytes, and the key regulatory cytokines and their interactions in SS |
| PMC1756898__F1 | Unraveling the Genetics of Human Obesity |
| PMC175791__F10 | Differential regulation of NFAT and SRF by the B cell receptor via a PLCG-Ca2+-dependent pathway |
| PMC1761701__F10 | Proposed model of lacritin mitogenic signaling pathway lacritin signaling suggested by data outlined in the text |
| PMC1763171__F2 | The inflammatory, coagulation, and fibrinolytic pathways are linked at many levels, leading to organ failure and eventually death |
| PMC1764624__F1 | Synthesis and breakdown of proteins by amino acids |
| PMC1766317__F5 | Model: A similar CARMA-Bcl10-MALT1 signaling pathway mediates NFKB activation in response to antigen receptor stimulation in lymphocytes and AT1R stimulation in liver cells |
| PMC1766780__F2 | Cytokine signalling and the pathogenesis of severe combined immunodeficiency (SCID) |
| PMC1766919__F1 | Signalling footprints of the TNF/TNF-R superfamily |
| PMC1767116__F3 | Mitochondrial death signalling pathways |
| PMC1768457__F1 | CD14/toll-like receptor 4 (TLR4) intracellular signalling complex |
| PMC1769518__F1 | Complement system consists of about 30 proteins that can be activated by 3 different cascades |
| PMC1769521__F2 | Senescence via tumor suppressor pathways |
| PMC1770611__F2 | Axin in Wnt signalling |
| PMC1770897__F4 | Model of TRD: The t haplotype encodes several Distorters (only two are shown), which are expressed in all sperm cells derived from a t/+ male and act on two opposing Rho signaling pathways regulating Smok1 |
| PMC1773546__F3 | The key proinflammatory pathway induced by enteric pathogens results in nuclear factor kappa B (NFKB) mediated transcription of interleukin 8 (IL-8) |
| PMC1773942__F1 | Flow chart summarising the cholesterol biosynthetic pathway, together with the structures and sites of action of the Tu 2208 and Ro 48-8071 inhibitors employed in this study |
| PMC1774081__F6 | Math1 signalling pathway |
| PMC1774101__F4 | Proposed framework for recruitment of T cells into the gut mucosa by activated CD40L+ platelets |
| PMC1774275__F1 | Simplified diagram of the Wnt/APC pathway |
| PMC1774275__F2 | Intrinsic, or mitochondrial, pathway (after Danial and Korsmeyer) |
| PMC1774275__F4 | The chromosomal instability (CIN) pathway (see text for details) |
| PMC1774275__F5 | Mitogenic signals are transduced by Ras which inhibits the retinoblastoma (Rb) protein allowing E2F and Myc to promote cell cycle progression |
| PMC1774279__F1 | Two major intracellular pathways cause apoptosis |
| PMC1774601__F2 | Death receptor mediated (extrinsic) pathway of apoptosis |
| PMC1774670__F2 | Interaction of JC virus (JCV) T-antigen with key growth regulatory pathways |
| PMC1774670__F6 | P53 pathway |
| PMC1774677__F1 | Diagrammatic indication of the cytokines, transcription factors, and signalling molecules which polarise virgin CD4 cells into T helper cell type I cells |
| PMC1774725__F1 | Tumour necrosis factor related apoptosis inducing ligand (TRAIL) receptor signalling |
| PMC1775040__F4 | WNT Pathways |
| PMC1779520__F3 | Signaling pathways activated by serum and GF treatments |
| PMC1779567__F6 | Functional dissection of signaling modules in human TReg cells |
| PMC1779623__F8 | Hmgcr in the Corpus Allatum Controls Sexual Dimorphism of Locomotor Activity and Body Size via the Insulin Pathway in Drosophila |
| PMC1779657__F2 | Recent observations on the regulation of fetal metabolism by glucose |
| PMC1779900__F6 | Some signaling pathways that could mediate long-term changes in cellular plasticity as a function of sexual experience |
| PMC1780025__F2 | Heterogeneity of Pacemaking Ability among SCN Neurons Robust rhythm generation in SCN neurons |
| PMC1781062__F1 | CCM2 as a Scaffold for p38 MAPK Activation |
| PMC1781473__F3 | Exploitation of Eukaryotic Ubiquitin Signaling Pathways by Effectors Translocated by Bacterial Type III and Type IV Secretion Systems |
| PMC1781924__F1 | Thy-1-associated signaling pathways |
| PMC1782125__F2 | (a)Signal transduction of TNFRI |
| PMC1782192__F2 | Direct and indirect activation of human natural killer (NK) cells |
| PMC1782267__F1 | TGFB1-Smad pathway |
| PMC1782267__F2 | TGF-TAK1 pathway |
| PMC1782438__F2 | Role of adaptors in T-cell signalling |
| PMC1782564__F6 | Hypothesized asthma cascade in hapten immune contact sensitized mice, consist of B-1 cell- to immunoglobulin M- (IgM) to complement-driven airway responses |
| PMC1782589__F2 | Signalling cascades of the LPS pathway and reported sites of IL-10 intervention |
| PMC1782796__F7 | Affinity maturation, a turning point between life and death for germinal centre (GC) B cells: a working hypothesis |
| PMC1783068__F1 | Proximal B-cell receptor-mediated signalling pathways |
| PMC1783401__F6 | Integration of Runx1 and the BMP signaling pathway into the SCL transcriptional network |
| PMC1783691__F1 | Differential Roles of Costimulatory Signaling Pathways in Type 1 Diabetes Mellitus |
| PMC1783813__F3 | Physiology and immunology of the cholinergic antiinflammatory pathway |
| PMC1785270__F6 | A model illustrating the positive and negative regulation of PanK2 activity |
| PMC1785339__F4 | Human and mouse mutations and the cognitive disorders affecting specific NRC/MASC signaling pathways and other postsynaptic proteins |
| PMC1794588__F3 | Small subnetwork identified for the shift from glucose to ethanol as carbon source |
| PMC1796761__F1 | Pathway of double-stranded break repair by homologous recombination and the factors involved |
| PMC1797319__F1 | Shewanella oneidensis MR-1 anaerobic carbon metabolism pathway |
| PMC1797585__F9 | Working model for NS action |
| PMC1797633__F1 | Strategies of the different HCV proteins to antagonize IFN therapy |
| PMC1798432__F8 | Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages |
| PMC1800873__F1 | Progression pathway network with w = 0.8, E = 0.8 and the LH algorithm |
| PMC1804347__F4 | Systemic sclerosis: a prototypic multisystem fibrotic disorder |
| PMC1804379__F7 | Aldosterone-induced Sgk1 relieves Dot1a-Af9–mediated transcriptional repression of epithelial Na+ channel A |
| PMC1805736__F6 | Pathways for synthesis of adrenal steroids |
| PMC1808970__F3 | AIRE expression is controlled by the lymphotoxin pathway |
| PMC1815248__F5 | Co-option of a developmental pathway by invasive tumors |
| PMC1817784__F2 | Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders |
| PMC1817805__F2 | AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer |
| PMC1817809__F1 | AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues |
| PMC1817809__F2 | AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance |
| PMC1819569__F6 | The signalling pathways involved in Pam3Cys-induced degranulation and cytokine/chemokine production in human LAD 2, MLMC and BMMC |
| PMC1820632__F1 | Cytokine-Effects on Glucocorticoid Receptor Function: Relevance to Glucocorticoid Resistance and the Pathophysiology and Treatment of Major Depression |
| PMC1820751__F3 | Ras signaling pathway relays growth signals from activated growth factor receptors to the nucleus |
| PMC182218__F2 | Osteoblasts express components necessary for coordinating mineralization of ECM and phosphate handling by the kidney |
| PMC1828067__F7 | Osteopontin/AvB3 signaling in the regulation of prostate cancer cell migration |
| PMC1828071__F1a | Intracellular Signaling in Insulin-mediated Regulation of Drug Metabolizing Enzyme Gene and Protein Expression |
| PMC1828071__F2 | Insulin-mediated activation of PI3K signaling pathways |
| PMC1828071__F3 | Diagrammatic representation of insulin on growth factor signaling through the Ras-Raf, MEK-ERK signaling pathway with downstream effects on gene transcription through ERK translocation |
| PMC1828075__F2 | Diagram showing several factors involved in lens development |
| PMC1828403__F1 | Representation of TLR4-signaling through the MyD88-dependent and MyD88-independent pathways |
| PMC1828869__F2 | Regulation of induction and vesicle nucleation |
| PMC1829400__F5 | TGFB signaling pathway |
| PMC1829419__F4 | Hypothetical regulatory network influencing honeybee pollen foraging behavior modulated by insulin-like signaling and its effects on ovarian development |
| PMC1832150__F1 | CoQ10biosynthetic pathway with eight known biosynthetic enzymes denoted as COQ1-8 |
| PMC1832185__F2 | Dose-dependent entry routes for the EGFR |
| PMC183833__F2 | Canonical Wnt/Beta-catenin pathway |
| PMC1838411__F1 | Roles of p16INK4a/RB-pathway in senescence cell cycle arrest |
| PMC1838573__F1 | Mitochondrial pathway through Bcl-2 family members |
| PMC1839882__F9 | Schematic illustration of the principal signaling pathways that are affected by sodium arsenite (As) treatment |
| PMC1839891__F1 | Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery |
| PMC1839891__F10 | In this model, the tumor growth process is replaced with the cell cycle model from figure 7 |
| PMC1847380__F14 | Signaling pathways leading to pseudohyphal growth |
| PMC1847380__F15 | Signaling pathways mediating the roles of Rho1 in cell wall assembly and actin organization |
| PMC1847401__F4 | Genes of the insulin/IGF-2 signaling pathway are required for induced stress resistance and induced life extension |
| PMC1847591__F1 | Drugs that regulate hepatic bile acid and other organic solute uptake, synthesis, detoxification and secretion |
| PMC1849962__F5 | Regulatory networks model of GSL biosynthetic pathway in Arabidopsis accession Columbia |
| PMC1850660__F1 | Summary of established Beta-catenin pathways |
| PMC1850774__F5 | Convergence of signaling pathways |
| PMC1851054__F6 | SFK-dependent PI3K-ERK2 and phospholipase CG-JNK1 pathways |
| PMC1851929__F8 | Proposed model for the activation of oligodendrocyte apoptosis by MHV infection |
| PMC1851974__F2 | Regulation of cyclin D1 degradation |
| PMC1852210__F1 | Diagram of folate and one-carbon metabolism in mammalian organisms |
| PMC1852238__F1 | Role of the glutathione pathway and ABC-transporter family in drug elimination and defense from ROS-mediated oxidative stress |
| PMC185249__F3 | Sprouty is a rapidly inducible negative regulator of fibroblast growth factor (FGF) pathway signaling |
| PMC185249__F4 | Signal transduction in the Transforming Growth Factor B(TGFB) family pathway is finely regulated at many levels |
| PMC1852551__F4 | Multiple estrogen-regulated steps in the metabolisms of prostaglandin J2 and retinoic acid are implicated in estrogen-dependent growth of human uterine fibroids |
| PMC1852708__F6 | Illustration of key proteins in the Rho GTPase signal-transduction pathway, focusing on the KALRN, CDGAP, and MYLK genes |
| PMC1852756__F2 | The small nuclear ribonucleoprotein biogenesis pathway |
| PMC1852792__F6 | A hypothetical model for association of four subcomplexes in the FA core complex |
| PMC1852964__F2 | Tyrosine phosphorylation of Beta-catenin, which transiently inactivates the E-cadherin-mediated cell adhesion system and may stimulate the APC-Beta-catenin-Tcf (Wingless-Wnt signaling) pathway, in streak lesions at the invading front of a colorectal cancer |
| PMC1853294__F10 | Cell injury to wound closure, including P2Y activation, intracellular Ca2+ release and EGFR signaling |
| PMC1854955__F7 | Schematic depiction of the molecular mechanism for the progression from HPS to chronic active disease or T-cell lymphoma in EBV-infected T cells |
| PMC1855985__F1 | Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4 |
| PMC1855986__F9 | ATM-Mediated Transcriptional and Developmental Responses to Gamma-rays in Arabidopsis . |
| PMC1855990__F2 | Identification of Key Processes Underlying Cancer Phenotypes Using Biologic Pathway Analysis |
| PMC1856251__F3 | Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine |
| PMC1856765__F3 | Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications |
| PMC1856765__F7 | Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications |
| PMC1856802__F2 | Canonical Wnt signalling pathway and its APC partner in colon cancer development |
| PMC1856802__F5 | Canonical Wnt signalling pathway and its APC partner in colon cancer development |
| PMC1857250__F2 | Tregs and rethinking cancer immunotherapy |
| PMC1857267__F2 | Altered macrophage differentiation and immune dysfunction in tumor development |
| PMC1857308__F9 | The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones |
| PMC1859939__F5 | Signal transduction pathways involved in Ha-ras-mediated AEG-1 induction |
| PMC1860011__F2 | PPARG as a new therapeutic target in inflammatory bowel diseases |
| PMC1860037__F1 | Role of interleukin 6 in a murine model of Crohn's ileitis: are cytokine/anticytokine strategies the future for IBD therapies? |
| PMC1860592__F2 | Biologic therapies: what and when? |
| PMC1862519__F1 | Intracellular signaling cascades activated by BDNF-stimulated autophosphorylation of TrkB receptors may affect prominent pathways responsible for elevations of intracellular Ca2+ levels in neurons |
| PMC186326__F7 | Model for Fgf18 regulation of long bone growth |
| PMC186370__F1 | Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon |
| PMC1866211__F1 | Hedgehog signalling pathway |
| PMC1866250__F7 | Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance |
| PMC1867237__F3 | ErbB/Ras pathway and Wnt pathway |
| PMC1867370__F9 | Root Phenotypes of Wild-Type, noxy2, and coi1-1 Plants Responding to Oxylipins.Ten-day-old seedlings grown on MS medium and in the presence of 9-HOT (25 μM), 9-oxo-C9 (15 μM), or JA (10 μM) |
| PMC1868540__F1 | Canonical Wnt Signaling Pathway |
| PMC1869626__F2 | Pathway analysis was performed using PathwayStudio software by importing three of the 32-up-regulated genes in our list |
| PMC1869627__F2 | Pathway diagram developed using the Ingenuity Pathways Analysis and Knowledge Base in which all genes changed by more than 1.5 fold were queried |
| PMC1874671__F2 | Genomic organization of the CDKN2A locus and description of involvement of its transcripts (p16INK4a and p14ARF) in the Rb and p53 pathways |
| PMC187486__F8 | Effects of Cdk4 disruption on the pathways controlling senescence and transformation |
| PMC1876599__F3 | Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR |
| PMC1876696__F1 | Pathways for the synthesis of the major phospholipids in S |
| PMC1876750__F2 | Focal Adhesions Regulate AB Signaling & Cell Death in Alzheimer’s Disease |
| PMC1877048__F1 | Nutritional Route Affects ERK Phosphorylation and Cytokine Production in Hepatic Mononuclear Cells |
| PMC1877091__F15 | PDCD10/MST4 signaling pathway and CCM protein function |
| PMC1878539__F1 | Unchecked thrombin is bad news for troubled arteries |
| PMC1884140__F11 | Schematic representation of the differentially expressed genes and how they are induced upon injection by (A) pristane or (B) phytol |
| PMC1885790__F3 | Diagram illustrating how the Rb and p53 pathways are linked to form a complex tumor suppressor network |
| PMC1885811__F4 | Web-accessible pathway navigator |
| PMC1885837__F6 | Obstructive nephropathy: insights from genetically engineered animals |
| PMC1885990__F1 | Scheme depicting a molecular pathway by which cell-cycle-related molecules promote cell death in neurons in development and disease |
| PMC1890373__F2 | Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands |
| PMC1890551__F1 | Eumelanin synthesis pathway and gene duplications in vertebrates |
| PMC1890551__F4 | Pteridine synthesis pathway and gene duplications in vertebrates |
| PMC1891745__F1 | Diagram illustrating Functional JAK STAT PathwayThis "JAK STAT" pathway appears to be ubiquitous amongst vertebrates |
| PMC1892100__F1 | Image showing the human insulin signaling pathway from BioCarta |
| PMC1892626__F3 | Regulation of hypoxia-inducible factor-1A (HIF-1A) and drug interventions currently in use |
| PMC1894940__F5 | Inhibition of COX-2 modulates multiple functional pathways during acute inflammation and pain |
| PMC1894978__F5 | The secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed |
| PMC1895551__F1 | Prosurvival signaling pathways and their downstream targets |
| PMC1895802__F1 | TGFB signaling pathway and mechanisms of inhibition during leukemogenesis |
| PMC1895816__F2 | Identification of a Bcr-Abl kinase signature |
| PMC1896004__F4 | Signaling pathways downstream of the Toll/TLRs |
| PMC1899305__F7 | GM-CSF Regulates a PU.1-Dependent Transcriptional Program Determining the Pulmonary Response to LPS |
| PMC1899380__F1 | Late steps in corrin ring biosynthesis in serovar Typhimurium |
| PMC1899878__F1 | Regulation of dimorphism in C |
| PMC1899901__F6 | A schematic model depicting the role of Artemis in the cellular response to IR |
| PMC1899924__F8 | Signaling pathways activated by mitogenic concentrations of TNFA and roles of furin, MT1-MMP, and MMP2 in the activation of the nSMase in mesenchymal cells |
| PMC1899931__F8 | Theoretical model depicting potential interactions in the intra-S checkpoint signaling pathway |
| PMC1899986__F8 | A model for cyclin E degradation regulated by two E3 ligases |
| PMC1900064__F7 | Proposed model for the signaling pathway by which leptin stimulates fatty acid oxidation and PPARA gene expression in C2C12 cells |
| PMC1900132__F1 | HCMV MIE promoter/enhancer and its cis-acting elements |
| PMC1904229__F12 | Schematic model of Zfra/WOX1 involvement in TNF signaling |
| PMC1904333__F2 | Hepcidin regulation: ironing out the details |
| PMC1904449__F3 | In silico modeling derived from Pathway Assist software analysis of differential gene expression in JRA neutrophils compared with healthy control subjects |
| PMC1905066__F5 | CRP and mannan-binding lectin (MBL) on complement activation |
| PMC1905373__F7 | Mechanism of complement-dependent haemolysis via the lectin pathway: role of the complement regulatory proteins |
| PMC1905729__F1 | Binding of IL-12 to the IL-12RB1 and B2 chains induces phosphorylation of the kinases Tyk2 and Jak2, which associate with the cytoplasmic tails of the B1 and B2 chains, respectively |
| PMC1905845__F1 | Schematic representation showing the plausible signaling events from uPAR integrin complex |
| PMC1913098__F1 | Sensitivity Analysis of Intracellular Signaling Pathway Kinetics Predicts Targets for Stem Cell Fate Control |
| PMC1913583__F1 | The methionine and folic acid cycles and the metabolic pathway of arsenic |
| PMC1914109__F8 | The p110D →RhoA →PTEN signalling pathway described in the text |
| PMC1919358__F5 | WNT signalling KEGG pathway consisting of three subpathways with the genes on the microarray encircled (A) and expression profiles of genes during porcine myogenesis (B) |
| PMC1924866__F5 | Striped view of multiple time-point comparisons |
| PMC1924866__F6 | Striped view of multiple data types |
| PMC1929113__F6 | Upregulation of cyclins and CDKs in melanoma cells |
| PMC1933158__F6 | A hypothetical model for the dual roles of insulin signaling in human brain |
| PMC1933372__F3 | RAN regulation pathway constituents exhibiting abundance changes, with a figure adapted from the GeneGo MetaCore database |
| PMC1934395__F2 | Combined Effects of Thrombosis Pathway Gene Variants Predict Cardiovascular Events |
| PMC1934514__F2 | Mechanisms of Action of GLP-1 in the Pancreas |
| PMC1934514__F4 | Schema outlining the signaling mechanisms reported to be involved in GLP-1R-induced differentiation/neogenesis of pancreatic precursor cells, proliferation and in the prevention of apoptosis |
| PMC1934518__F2 | Ligands identified for EpCAM and possible functions related to them |
| PMC1936363__F1 | Epidermal growth factor receptor pathway |
| PMC1937523__F3 | Comparison between the gene expression profiles and predicted substrate uptake rates |
| PMC1937548__F4 | Comparison of nonsynonymous substitution rates among members of RB and p53 signaling pathways |
| PMC19384__F10 | A model of thymic differentiation |
| PMC1939900__F6 | Different signaling pathway mediated by A3(IV)NC1 |
| PMC1940036__F6 | Wnt/Axin1/Beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries |
| PMC1940051__F2 | TGFB signaling pathway |
| PMC1948012__F10 | Action for AICAR in human leukemia ALL cells |
| PMC1949901__F1 | Current understanding of the pathways of fatty acid synthesis which are known to occur within the Brassicaceae |
| PMC1951379__F6 | IFN signaling during the clinical evolution of SARS |
| PMC1951533__F14 | Proline-Rich Tyrosine Kinase 2 Mediates Gonadotropin-Releasing Hormone Signaling |
| PMC1951772__F8 | PI3K activation by eIF2A kinases |
| PMC1952166__F1 | Signaling cascades required for TCR-mediated integrin activation |
| PMC1952230__F1 | Regulation of CXCR4 Signaling |
| PMC1952634__F4 | Evolving biology and treatment of prostate cancer |
| PMC1952636__F9 | Beta-Arrestin-mediated B1-adrenergic receptor transactivation of the EGFR confers cardioprotection |
| PMC1952644__F1 | Alternative signaling: cardiomyocyte B1-adrenergic receptors signal through EGFRs |
| PMC1952649__F2 | Two tales concerning skeletal muscle. |
| PMC1955177__F3 | Cell death in the cardiovascular system |
| PMC1955758__F2 | How both apoptotic death and immunity may be triggered by dsRNA |
| PMC1958996__F2 | Transcriptional control of adipocyte formation |
| PMC1959234__F1 | Schematic model for the "error-free" BRCA double strand break repair pathway Brief overview of components within the BRCA pathway used here as a working model that was tested here |
| PMC195990__F5 | A model of Hip1's role in lung branching morphogenesis |
| PMC196255__F1a | Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway |
| PMC1963413__F1 | Oval of iNOS-inducing signaling pathways |
| PMC1963416__F1 | Signaling mechanisms for the activation of HAT and HDAC |
| PMC1964512__F3 | Type I IFN innate immune response to adenovirus-mediated IFNG gene transfer contributes to the regression of cutaneous lymphomas |
| PMC1964754__F6 | Furin in development, homeostasis and disease |
| PMC1964795__F5 | INHIBITION OF MAPK AND STIMULATION OF AKT KINASE SIGNALING PATHWAYS: TWO APPROACHES WITH THERAPEUTIC POTENTIAL IN THE TREATMENT OF NEURODEGENERATIVE DISEASE |
| PMC1965265__F6 | A schematic representation of differential testosterone action on morphoregulatory gene expression in the rat VP and LP lobes |
| PMC1971124__F4 | BDCA2/FcERIG Complex Signals through a Novel BCR-Like Pathway in Human Plasmacytoid Dendritic Cells. |
| PMC1974867__F9 | Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis |
| PMC1974879__F1 | Transcriptional profile of Rous Sarcoma Virus transformed chicken embryo fibroblasts reveals new signaling targets of viral-src |
| PMC1974887__F1 | Endogenous Synthesis of Coenzyme Q in Eukaryotes |
| PMC1975829__F1 | Viral infections: beneficial role of eosinophils |
| PMC1976272__F7 | Hypothetical role of Hsp72 in the regulation of oxidative stress-induced HMGB1 cytoplasmic translocation and release |
| PMC1978064__F4 | MiR-103/107 and PANKs may constitute coordinated transcription units with synergistic cellular effects concerning cellular acetyl-CoA levels and other metabolic pathway elements |
| PMC198547__F8 | Leptin action on the TRH neuron |
| PMC1986651__F1 | Regulation of cell proliferation and cell death by PKCE |
| PMC1988867__F7 | Ingenuity pathway analysis showing regulatory relationships among differentially expressed transcripts |
| PMC1991338__F1 | ZIP1 expression and zinc accumulation in the pathway and bioenergetics of citrate production and citrate oxidation in normal versus malignant prostate cells |
| PMC199174__F9 | Models for the function of Ser307 phosphorylation |
| PMC199181__F2 | Proposed mechanisms of NFKB activation in HIV-1-infected cells |
| PMC199181__F3 | The NFKB pathway by viruses |
| PMC1992444__F3 | Interaction map of the Notch signaling pathway |
| PMC1992519__F2 | Signaling on the endocytic pathway |
| PMC1993849__F7 | Ischemic/hypoxic effects on cardiac myocytes and stem cells |
| PMC1993861__F7 | Model summarizing the hypothesis on narciclasine-mediated apoptosis |
| PMC1993906__F13 | The G12/13 signaling pathway |
| PMC1993906__F16 | Adenylyl cyclases are targets of multiple regulatory signaling pathways and respond differently, depending on which group they belong to |
| PMC1994616__F1 | New molecularly targeted therapies for lung cancer |
| PMC1994616__F2 | New molecularly targeted therapies for lung cancer |
| PMC1995566__F7 | Oxidative stress initiates a cascade of reactions leading to cell death via one or more sequences of molecular events |
| PMC1995599__F2 | MOLECULAR AND CELLULAR MECHANISMS OF THE ANABOLIC EFFECT OF INTERMITTENT PTH |
| PMC1998879__F2 | Molecular pathway associated with neuronal migration |
| PMC1998884__F1 | Pathways involved in GSIS |
| PMC1999497__F2 | Flow diagram of the P53/apoptosis pathway |
| PMC2000831__F3 | Proliferation induced by androgen independent pathways |
| PMC2002564__F1 | Arterial-venous specification in the developing embryo |
| PMC20092__F5 | A model for the v-Crk-mediated signaling pathway |
| PMC2013735__F4 | GenMapp pathway showing the impact of 1 week of STZ-DM on transcription in pathways related to cytokines and the inflammatory response |
| PMC2013861__F4 | Signalling pathways activated by the RXFPs |
| PMC2014644__F2 | PGE2-EP receptor signaling pathways |
| PMC2039930__F7 | Signal transduction pathways involved in Ha-ras-mediated AEG-1 induction |
| PMC2040031__F1 | INTERLINKING INTERLEUKIN-7 |
| PMC2040891__F5 | UVB acts at both the switch and the switched pathway to trigger UV-induced apoptosis |
| PMC2042021__F6 | Contrasting Infection Strategies in Generalist and Specialist Wasp Parasitoids of Drosophila melanogaster |
| PMC2042025__F3 | Notch pathway is a frequent target of insertion |
| PMC2042178__F2 | PTEN/PI3K/mTOR/STAT3 signaling involved in breast cancer stem-like cell survival and proliferation |
| PMC2043390__F9 | Biphasic expression and up-regulation of HWP1 at the bud-hypha transition |
| PMC2043401__F1 | Schematic outline of fatty acid synthesis in apicomplexans |
| PMC20438__F5 | Schematic diagram of possible Rad6-mediated metabolic pathways |
| PMC204456__F5 | Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans |
| PMC20445__F6 | Schematic diagram showing steps in the signaling pathway by which P |
| PMC2045534__F6 | Schematic model of the role played by GADD34 and the mTOR pathway in the suppression of viral replication |
| PMC2045624__F1 | OX40 signaling directly triggers the antitumor effects of NKT cells |
| PMC2048738__F1 | Reactions of the Calvin cycle, starch synthesis, photosynthetic carbon oxygenation pathway, triose-P export, and Suc synthesis represented in the model (Supplemental Appendix S1, A and B) |
| PMC2062474__F3 | From Endosymbiont to Host-Controlled Organelle: The Hijacking of Mitochondrial Protein Synthesis and Metabolism |
| PMC2063509__F1 | AUTOPHAGY: HIGHLIGHTING A NOVEL PLAYER IN THE AUTOIMMUNITY SCENARIO |
| PMC2063513__F6 | Gene Expression in Human Hippocampus from Cocaine Abusers Identifies Genes which Regulate Extracellular Matrix Remodeling |
| PMC2063536__F7 | ES cell-based model describing the ontogeny of NSCs |
| PMC2063755__F1 | Signaling events during EMT |
| PMC2063819__F7 | The newly identified NT3-activated signaling pathway |
| PMC2064427__F10 | Schematic diagram illustrating the signaling mechanisms that control the bidirectional responses of the growth cone to BMP7 gradients |
| PMC2064670__F5 | Model integrating calcium mobilization into the Fas signaling pathway |
| PMC2064799__F9 | New calpain-dependent switch that controls cell spreading and retraction |
| PMC2064840__F9 | Divergent TGFB signaling pathways induce transcriptional regulation through Smads and translational regulation through the mTORC1 pathway |
| PMC2066195__F10 | IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice |
| PMC206993__F9 | SPARC-mediated regulation of and coupling to the TGFB signaling system |
| PMC2071927__F2 | TUNING IMMUNE TOLERANCE WITH VASOACTIVE INTESTINAL PEPTIDE: A NEW THERAPEUTIC APPROACH FOR IMMUNE DISORDERS |
| PMC2074956__F3 | Schematic representation of the carbon catabolic pathway, the bifid shunt, and oxalic acid degradation |
| PMC2075035__F2 | Scheme of the Leloir pathway |
| PMC2075035__F4 | Scheme of the LNB/GNB pathway in B |
| PMC2075101__F1 | 5-HT2A receptor agonists cause activation of GAq/11 proteins which in turn activate the second messenger enzyme PLC |
| PMC2075270__F1 | Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle |
| PMC2077852__F3 | Dmp1 links the Rb and p53 pathways |
| PMC2077853__F9 | Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation |
| PMC2078333__F1 | Summary of known actions of activated ras-p21 in cells, beginning (top, left) when a growth factor binds to its cell receptor |
| PMC2080843__F5 | Simulation of the Apoptosis pathway under FasL stimulation (black starred line), bacterial only (red circled line) and both (blue triangled line) |
| PMC2080907__F8 | Myc and Ca2+signaling events downstream of the pre-BCR/BCR |
| PMC2082051__F5 | Networks of pathways unique in the HIV-1 regulated mPBMCs |
| PMC2082128__F7 | Biosynthetic pathway for the ganglio-series of glycosphingolipids |
| PMC2083698__F6 | Promiscuous Mutations Activate the Non-Canonical NF-kB Pathway in Multiple Myeloma |
| PMC208733__F1 | Regulation of the Foxa and Foxo transcription factors through PI3-kinase signaling |
| PMC2089068__F3 | Relative transcript levels for genes from carbon central metabolism for PB12 (first value) and PB13 (second value), as compared to JM101 |
| PMC2089068__F4 | Relative transcript levels for genes from carbon central metabolism for L-Phe overproducing strains |
| PMC209288__F1 | The biosynthetic pathway for the fibrillar collagens expressed in skin, identifying steps that are affected in different forms of EDS |
| PMC2093951__F9 | NOVEL VIP SIGNALING PATHWAY IN T CELLS cAMP→Protein Tyrosine Phosphatase (SHP-2?)→JAK2/STAT4→Th1 differentiation |
| PMC209410__F1 | The EXT proteins and HS biosynthesis |
| PMC209410__F2 | A working model of mammalian bone development |
| PMC2094118__F1 | The HIF1 pathway in normoxia (A) and hypoxia (B) |
| PMC2094129__F2 | Respective balance between Gi- and Gs-dependent signalling pathways and their roles in the modification of FcARI-mediated mast cell degranulation |
| PMC209413__F1 | The TGF-&bgr;/Smad pathway and its interrelationship with mediators of inflammatory signals |
| PMC209477__F2 | gp130 cytokine family pathways on anterior pituitary cells |
| PMC209479__F1 | Corticotroph SOCS-3 as an intracellular suppressor of cytokine signaling |
| PMC209479__F2 | Inhibitory effects of SOCS-3 and SHP-1 on LIF-mediated gene expression |
| PMC2096753__F1 | Summary of purinergic pathways involved in microglial response |
| PMC2097959__F2 | INTEGRATING RADIOTHERAPY WITH EGFR ANTAGONISTS AND OTHER MOLECULAR THERAPEUTICS FOR THE TREATMENT OF HEAD AND NECK CANCER |
| PMC2099483__F1 | Circadian oscillation in leptin signaling pathway in mouse brown fat |
| PMC2099624__F9 | Schematic model of Nrf2 regulation by Keap1 |
| PMC2100073__F6 | Filamentation signaling pathway recovered completely |
| PMC2100342__F3 | Activation of NFKB via the classical and the alternative pathway |
| PMC2100400__F2 | Innate and Adaptive Immune Response to Apoptotic Cells |
| PMC2100434__F2 | Growth hormone-mediated JAK/STAT signal transduction |
| PMC2106361__F1 | Current model of the Fanconi anemia pathway |
| PMC2106369__F1 | Schematic overview of the RANK-NFKB signalling pathway |
| PMC2118167__F7 | Proposed model for the intersection of innate and adaptive immunity during polysaccharide-induced abscess formation in the peritoneal cavity |
| PMC2118421__F7 | Proposed model of RasGRP1 in FcɛRI-mediated signaling |
| PMC2121320__F2 | MTA family of coregulators in nuclear receptor biology and pathology |
| PMC2128044__F12 | Hierarchical representation of the JAK-STAT pathway with SOCS1 subsystem as a coordinator |
| PMC2131730__F4 | LPS signals the TLR4 pathway on an APC (i.e., monocyte or dendritic cell) |
| PMC2133067__F8 | Working model of the PTEN regulatory network |
| PMC2133163__F6 | Anchorage-dependent cell growth |
| PMC2133187__F8 | A proposed functional role for PKC BII in colon carcinogenesis |
| PMC2134838__F2 | ALTERNATE ROUTES FOR DRUG DELIVERY TO THE CELL INTERIOR |
| PMC2134904__F7 | Schematic representation of the effects of RhoA/ROCK signaling pathway inhibition on membrane FasL expression and lymphocytes apoptosis |
| PMC2134905__F2 | The p53 pathway and IGFBP3 |
| PMC2136409__F7 | Genetic and epigenetic mechanisms of gene regulation during lens development |
| PMC2136409__F8a | Genetic and epigenetic mechanisms of gene regulation during lens development |
| PMC213796__F7 | EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer |
| PMC2147077__F4 | A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety. |
| PMC2147675__F1 | Antimalarial therapy prevents Myc-induced lymphoma |
| PMC2148057__F5 | GenMAPP view of energy production pathway in MCF-7 and ZR75-1 cells |
| PMC2148057__F6 | Sugar metabolism pathways in MCF-7 and ZR75-1 cells profiled by GenMAPP |
| PMC2148057__F8 | Proteosomal degradation pathway |
| PMC2148066__F6 | GenMAPP pathway showing changes in expression of the transcription factor PPARA and fatty-acid degrading enzymes upon fasting |
| PMC2149843__F1 | A pro-adhesive PPARGamma-mediated chemokine receptor switch, CCR2→CX3CR1, in atherosclerosis |
| PMC2150790__F9 | The signaling pathways activated by N |
| PMC2151350__F2 | Model for renal pathology in Dent's disease (due to a loss of ClC-5) The small peptide PTH (parathyroid hormone) and various forms of vitamin D (VitD; bound to their binding protein) pass the glomerular filter into the early proximal tubule (A) |
| PMC2151384__F2 | CON and NR samples; black/white boxes denote genes not detected on the human genechip with baboon RNA generated probe |
| PMC2151841__F4 | Signal transduction pathway in the UPR |
| PMC2151969__F4 | Genes up-regulated and down-regulated by FGF-2 in IGF-I signaling pathway |
| PMC2151969__F5 | Genes up-regulated and down-regulated by FGF-2 in TGFB signaling pathway |
| PMC2153436__F4 | Immune Response and Cell Cycle Networks |
| PMC2153443__F8 | TGFB SIGNALING BY PROINFLAMMATORY CYTOKINES IN ARTICULAR CHONDROCYTES |
| PMC2168342__F7 | Matrilysin and stromelysin-2 differentially control apoptotic transcriptional response |
| PMC2168724__F1 | Coenzyme B12 biosynthesis in serovar Typhimurium |
| PMC2168916__F7 | Regulation of the AHR-XRE pathway by NRF2 |
| PMC2169053__F6 | Model for SCF-mediated regulation of hFBH1 and Srs2 turnover in response to DNA damage |
| PMC2169177__F10 | Schematic view of Ras- and calcineurin-dependent pathways in T cells |
| PMC2171390__F7 | Calcium-independent microtubule-dependent pathway is required for FcɛRI-mediated degranulation in mast cells |
| PMC2171731__F9 | Invadopodium formation |
| PMC2171933__F7 | The control of cell migration by integrin-specific regulation of Rho GTPases |
| PMC2172299__F8 | A hypothetical model showing the roles of Fak and paxillin in motile HeLa cells |
| PMC2172491__F1 | The PI3K–Akt–TSC–TOR pathway and feedback regulation of insulin/IGF-I signaling |
| PMC2172900__F9 | A model of how the Tor1/2 and Lst8 proteins affect amino acid biosynthesis and Gap1p sorting |
| PMC2173020__F1 | Cross-talk between growth factors and integrins in endothelial cells |
| PMC2173691__F7 | Mechanisms of E-cadherin regulation in sparse and dense cultures of colon cancer cells |
| PMC2173816__F3 | Down-regulation of the inflammatory response |
| PMC2173906__F7 | Hypothetical scheme of the mechanism by which Dkk1 promotes osteolytic lesions in vivo |
| PMC2174913__F2 | Checkpoints activated upon rereplication |
| PMC2174972__F7 | The Viral Oncoprotein LMP1 Exploits TRADD for Signaling by Masking Its Apoptotic Activity |
| PMC2175095__F10 | Model depicting the role of CAS/Crk and ERK signaling pathways in mediating cell migration and suppressing apoptosis during invasion of the ECM |
| PMC2175514__F5 | Transcription regulatory network indicates utilization of various transcription factors following activation of TLR7 |
| PMC2175514__F9 | Protein regulatory network indicates importance of ISGylation pathway in TLR7-mediated activation of pDC |
| PMC2176131__F7 | Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor-B Signaling |
| PMC2180215__F1 | Comparison of the protein kinase/phosphatase signaling pathways in flies, worms, and humans (see text for description) |
| PMC2180420__F9 | Co-coculture system reveals the involvement of intercellular pathways as mediators of the lutropin receptor (LHR)-stimulated ERK1/2 phosphorylation in Leydig cells |
| PMC219066__F1 | Tocopherol biosynthesis in plants |
| PMC2192627__F1 | Signaling mechanisms involved in lifespan regulation and the cellular response to genotoxic stress |
| PMC2193446__F7 | The hypothesized biochemical pathway responsible for the hyperproliferative phenotype of Nf1 +/- mast cells in response to SCF |
| PMC2193492__F1 | Pathways initiating transcription from pIV of the CIITA gene |
| PMC2194036__F8 | Biosynthetic scheme proposed for resolvins: aspirin-triggered omega-3-derived products |
| PMC2194080__F1 | Proposed mechanism of CD4+ T cell priming after Leishmania major infection |
| PMC2194118__F6 | Molecular dissection of the signaling cascade underlying BCR-controlled integrin A4B1-mediated adhesion |
| PMC2194763__F5 | Cell cycle pathway diagram obtained from GenMAPP (Gene Map Annotator and Pathway Profiler, Gladstone Institutes, University of San Francisco, San Francisco, CA [38] |
| PMC219483__F1 | Biochemical pathways of TSH and folate metabolism in Leishmania |
| PMC2195651__F1 | Fas (death receptor) signaling pathway and its inhibition |
| PMC2195768__F6 | Proposed signaling pathway of the purinergic receptor: regulation of cardiac autonomic activity |
| PMC2195865__F1 | Extrinsic and intrinsic cell death signaling pathways |
| PMC2195905__F10 | Hypothetical model for the role of c-FLIPL in affinity maturation of the Ab response |
| PMC2195911__F10 | A molecular mechanism whereby cAMP inhibits T cell function |
| PMC2196031__F8 | Schematic presentation of the proposed sites of inhibition of the ceramide pathway by CrmA and Bcl-2 |
| PMC2196458__F7 | Fas-signaling pathways in relation to the cytoskeletal networks, the Golgi-sorting compartment, and the surface membrane |
| PMC2198843__F1 | Adhesion regulation of nucleocytoplasmic trafficking of signaling molecules |
| PMC2202913__F1 | Control of Food Intake by the Hypothalamic Leptin-Melanocortin PathwayThe hypothalamus receives and integrates neural, metabolic, and hormonal signals to regulate energy homeostasis |
| PMC2203613__F10 | Functional interacteome of all parietal cortex proteins |
| PMC2206000__F2 | Molecules and pathways implicated in sulfur mustard (SM)-induced apoptosis |
| PMC2206598__F4 | Regulatory networks sensitive to tyrosine kinase inhibitors in H3255 and MKN45 cells revealed by PhosphpScan-SILAC study |
| PMC2211634__F3 | Models for the dual roles of KLF4 and KLF5 in tumor suppression and oncogenesis |
| PMC2212135__F6 | Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2 |
| PMC2212277__F6 | Model to illustrate how SHP-2 regulates coupling of the TCR to the Ras/MAPK pathway |
| PMC2212359__F5 | HToll and TNFR-1 signaling pathways |
| PMC2212850__F2 | Major signaling pathways for type I IFN gene transcription |
| PMC2213034__F8 | Our model for the mechanism of anti-CD63 inhibition |
| PMC2213056__F1 | AID-initiated SHM pathways |
| PMC2213208__F1 | Activation of the vagus nerve leads to the release of acetylcholine (Ach) that binds to Alpha-7 nicotinic receptors (A7 nAChR) on cytokine producing cells |
| PMC2213224__F8 | Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion |
| PMC2214701__F3 | Building bone to reverse osteoporosis and repair fractures |
| PMC2215060__F1a | WE GATHER TOGETHER: INSULATORS AND GENOME ORGANIZATION |
| PMC2215765__F1 | Schematic overview of the LPS TLR4 signaling pathway |
| PMC2217489__F4 | F igure 4 |
| PMC2219351__F1 | Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients |
| PMC2219551__F7 | Signaling Pathway Involved in Neutrophil Elastase-Stimulated MUC1 Transcription |
| PMC2220082__F2 | Rosilitazone stimulates NSCLC proliferation by affecting the Akt/mTOR pathway through PPARGamma-dependent and PPARGamma-independent mechanisms |
| PMC2223843__F2 | TLR3 signaling pathways |
| PMC2224366__F9 | Innate immune modulation of CTL response to LCMV through MyD88 signaling |
| PMC2224586__F3 | HCMV regulates the expression of multiple components of the NFKB signaling pathway (see Table and Table S1 in the supplemental material for abbreviations) |
| PMC2224766__F3 | Proposed metabolic pathway for PSI-6130 |
| PMC2225459__F2 | Schema illustrating the effects of (a) metformin- or AICAR-induced AMPK activation, (b)adiponectin, and (c) TZDs or PPAR alpha ligands on the rat granulosa cell steroidogenesis |
| PMC2225983__F3 | PI3K-AKT pathway is transcriptionally regulated throughout the lactation cycle |
| PMC2228275__F3 | A signaling network links genes regulated by GCs in CEM cells |
| PMC2230579__F10 | Left, the mechanism, described by , for the proapoptotic function of TSP1 or 2 |
| PMC2233667__F6 | Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens |
| PMC2233890__F4 | Multiple ERK scaffold regulate growth factor and adhesion signaling |
| PMC2234347__F2 | CNX/CRT cycle |
| PMC2234366__F1 | Alternative models for selective Th1/Th2 induction by DCs |
| PMC2234385__F10 | Model of TLR ligand activation of Kupffer cell-NK cell cross talk in co-culture |
| PMC2234434__F3 | Genes involved in apoptotic pathways were altered in type II cells isolated from Stat3ÃŽâ€/Άmice |
| PMC2235195__F1 | RA synthesis pathway |
| PMC2235216__F1 | Arsenic-induced acquired androgen independence |
| PMC22365__F5 | Evolutionary conservation of the DNA damage and the replication checkpoints |
| PMC2238720__F2 | Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions |
| PMC2238789__F2 | a Cell processes predicted to be influenced by the top up-regulated priority genes (164 genes showing a differential expression >1 log2) based on in silico analysis employing the ResNet database (PathwayStudio 5.0, Ariadne) |
| PMC2238789__F3 | Hypothetical 'super pathway' not stratified for cell type illustrating known direct interactions between the 892 PD priority genes (regulation, expression and promoter binding only) |
| PMC2238789__F4 | Neuronal pathway containing proteins found in Lewy bodies [] |
| PMC2238789__F5 | Interactions of known PD genes (marked yellow) with the priority genes of this study |
| PMC2238877__F4 | PharmGKB Irinotecan Pathway |
| PMC2241839__F3 | Cholesterol biosynthesis pathway |
| PMC2242658__F8 | Wingless and integration site growth factor (WNT)-induced epidermal growth factor receptor (EGFR) transactivation |
| PMC2242712__F1 | Phenolic lipid synthesis in A |
| PMC2242750__F1 | Schematic representation of GADS-related signaling in T cells |
| PMC2242778__F5 | Canonical pathway analysis |
| PMC2242820__F5 | Modeling Cancer Progression via Pathway Dependencies |
| PMC2245955__F5 | Gene expression changes observed in Sema3A signaling pathway |
| PMC2246131__F7 | Schematic diagram showing the possible effects of the reelin pathway in protection from CM |
| PMC2246264__F9 | Proposed mechanism for MnSOD-mediated mitochondria to nucleus signaling and crosstalk with the IIS pathway |
| PMC22464__F5 | Metabolic reaction network analyzed from the human erythrocyte containing 29 metabolites and the related 51 fluxes (37 internal and 14 exchange fluxes) |
| PMC2247392__F2 | Growth factors trigger local and long distance signalling |
| PMC2248159__F2 | A part of the yeast cell cycle pathway available from KEGG [26] |
| PMC2253531__F5 | Induction of immune response to Wolbachia infection in S2 cells |
| PMC2254178__F1 | Vital Elements of the Wnt-Frizzled Signaling Pathway in the Nervous System |
| PMC2254474__F1 | P2Y receptor-mediated signalling cascades in C6 cells |
| PMC2254485__F5 | Tumour growth and metastasis: Role of NPP2-catalyzed reactions |
| PMC2254585__F5 | In silico knockout of PLCG1 in the HGF stimulated signalling network |
| PMC2254980__F3 | Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice |
| PMC2254980__F4 | Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice |
| PMC2257939__F2 | Bimodal genes highlighted in KEGG ECM-receptor interaction diagram |
| PMC2258259__F1 | Metabolic pathways involved in pyrimidine metabolism |
| PMC2258669__F1 | Genomic and functional context of glycerate kinase enzymes in bacteria |
| PMC2258669__F3 | Enzymatic reactions and assays |
| PMC2258989__F6 | Schematic presentation of the signaling pathway induced by HCV core protein for insulin resistance in human hepatocytes |
| PMC2259254__F2 | Balance between muscle hypertrophy and atrophy depends on whether protein synthesis is more active than degradation or vice versa |
| PMC2259386__F1 | Prototypical myelin-derived neurite growth inhibitors, their receptors and intracellular signaling pathway |
| PMC2259464__F2 | TGFB signaling pathway |
| PMC2262896__F4 | TCR signaling pathway |
| PMC2262896__F6 | Interferon signaling |
| PMC2263022__F6 | Superposition of 'omics' data on maps |
| PMC2265304__F1 | Idiopathic Pulmonary Fibrosis: Aberrant Recapitulation of Developmental Programs? |
| PMC2266095__F2 | Schematic presentation of the NFKB signaling network in radiation-induced adaptive radioresistance |
| PMC2266794__F4 | Integrative Genome-Wide Expression Analysis Bears Evidence of Estrogen Receptor-Independent Transcription in Heregulin-Stimulated MCF-7 Cells |
| PMC22667__F1 | Pheromone response pathway in yeast and summary of epistatic interactions with STE4 and STE11 |
| PMC2267252__F2 | Apoptosis map |
| PMC2267299__F1 | Age-associated perturbations in glutathione synthesis in mouse liver |
| PMC22672__F8 | Orb6 kinase is proposed to be part of a regulatory cascade contributing to the mitotic control and responding to the Ras1 and Cdc42-dependent morphological control pathway via the Pak1/Shk1 kinase |
| PMC2267714__F3 | Gene expression changes detected in selected pathways in M group |
| PMC2267731__F2 | BL module: A network visualization of the top 25 scoring genes in BL |
| PMC2268054__F1 | Role of glycoprotein 130 (gp130) downstream signalling in the heart |
| PMC2268054__F2 | Mutations in the glycoprotein 130 (gp130) receptor lead to an imbalance in downstream signalling pathways |
| PMC2268064__F2 | Signalling pathways leading to the phosphorylation and inhibition of glycogen synthase kinase 3 (GSK3) |
| PMC2268064__F3 | Regulation of the transcriptional co-regulator Beta-catenin |
| PMC2268661__F2 | The diagram of GSH redox cycle |
| PMC2268699__F1 | p38 MAPK canonical signalling pathway |
| PMC2268699__F2 | FGF canonical signalling pathway |
| PMC2268740__F1 | Neuroarchitecture of Aminergic Systems in the Larval Ventral Ganglion of Drosophila melanogaster |
| PMC2268796__F6 | The signaling pathways regulating cell cycle and differentiation in tumor cells in response to shear stress |
| PMC2268956__F3 | The major pathways leading to apoptosis |
| PMC2268988__F3 | Life and death decisions by the E2F transcription factors |
| PMC2269037__F3 | PI3K/AKT signaling pathway activated by 3Alpha-diol |
| PMC2269652__F12 | Purinoceptor-coupled Cl− channels in mouse heart: a novel, alternative pathway for CFTR regulation |
| PMC2270259__F3 | Central metabolism |
| PMC2270353__F4 | NPTX2 pathway obtained by means of the Resnet 5.0 eukaryotic database of molecular interactions (Ariadne) overlayed with microarray expression values |
| PMC2270852__F5 | Schematic of signaling pathways in PDAC |
| PMC2274947__F6 | Acrolein-Activated Matrix Metalloproteinase 9 Contributes to Persistent Mucin Production |
| PMC22753__F6 | A signal transduction pathway leading to the phosphorylation and activation of mTOR in response to insulin |
| PMC2275788__F2 | Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast |
| PMC2276341__F3 | Network analysis of target genes |
| PMC2276649__F8 | GSK-3B Targets Cdc25A for Ubiquitin-Mediated Proteolysis and GSK-3B Inactivation Correlates with Cdc25A Overproduction in Human Cancers |
| PMC2276852__F7 | Schematic representation of the proposed events triggered by exposure to replication inhibitors such as APH |
| PMC2276871__F1 | Steroid receptor expression in postnatal day 5-10 developing prostates from oil-treated control rats (A) and neonatally estrogenized rats (B) |
| PMC2277216__F1 | Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history |
| PMC2277398__F1 | MAP kinase pathway analysis of the meta-modes |
| PMC2277413__F4 | Gene Network A |
| PMC2277413__F5 | Gene Network B |
| PMC2277498__F3 | Pharmokinetic Limitations of Antioxidant Treatment for COPD |
| PMC2278039__F2 | FIP200, a key signaling node to coordinately regulate various cellular processes |
| PMC2278091__F1 | F igure 1.– |
| PMC2279152__F1 | Apoptosis signalling pathways |
| PMC2279300__F6 | Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors |
| PMC2287275__F2 | Mesenchymal stem cell dysfunction in HGPS |
| PMC2287285__F7 | Comparison models summarizing how eIF4E is not only downstream of the PI3K–AKT pathway (left) but can modulate this PI3K–Akt axis through NBS1 (right) |
| PMC2288663__F6 | Nucleotide excision repair pathway |
| PMC2290973__F2 | Pathway Studio diagram of common regulators of differentially expressed genes |
| PMC2291030__F3 | EGF signaling pathway generated by the Ingenuity Pathway Analysis (IPA) software |
| PMC2291100__F1 | Proposed biosynthetic pathway of Tcm PKS and a comparison of hypothetical intermediates for two possible folding pathways |
| PMC2291295__F1 | Keratinocyte Apoptosis in Epidermal Development and Disease |
| PMC2291295__F2 | Keratinocyte Apoptosis in Epidermal Development and Disease |
| PMC2292467__F6 | DNA replication and damage checkpoint regulation |
| PMC2292640__F1 | SARS CORONAVIRUS AND INNATE IMMUNITY |
| PMC2293084__F8 | PARP-1 in NFAT signaling pathway |
| PMC2293256__F4 | Reannotation processes |
| PMC230332__F7 | Extracellular and intracellular antagonism of BMP signaling by myostatin and TGFB |
| PMC2311275__F4 | Following biological functions (central carbon pathway, redox and respiration coordination, phosphate starvation, nitrogen gestion, carbohydrates, nucleotide and amino acids metabolism, ribosome activity) |
| PMC2311292__F2 | Pathway representation of all the tryptophan related genes analyzed |
| PMC2311419__F1 | P. gingivalis accelerates gingival epithelial cell progression through the cell cycle |
| PMC23119__F3 | Roles of INH-induced genes in the context of a proposed pathway for mycolic acid biosynthesis |
| PMC2312359__F4 | Composite list of expressed genes and enriched transcription factors implicates specific regulatory networks |
| PMC2315681__F8 | Leptin's roles in the endocardial cushion |
| PMC2315691__F1 | Complement system and complement regulatory proteins (CRegs) |
| PMC2322867__F2 | Rapid Signaling Mechanisms of Estrogens in the Developing Cerebellum |
| PMC2323197__F1 | Immunosuppression in islet transplantation |
| PMC2323406__F4 | Stimulus Design for Model Selection and Validation in Cell Signaling |
| PMC2329845__F2 | IPA of the genes encompassed by the conserved 166 signatures and belonging to the Wnt signal transduction pathway |
| PMC2330230__F9 | Candidate interactors and their putative postion in the Frizzled signaling pathway |
| PMC2330246__F1 | Overview of NAD biosynthesis and salvage pathways and a link with other metabolic pathways via ADP-ribose |
| PMC2330263__F2 | Integration of Progesterone Receptor Action with Rapid Signaling Events in Breast Cancer Models |
| PMC2342468__F1 | Cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice |
| PMC2346559__F1 | An Allosteric Mechanism for Switching between Parallel Tracks in Mammalian Sulfur Metabolism |
| PMC2349095__F2 | Triggering and amplification of the Wnt/Beta-catenin pathway in osteocytes in response to load |
| PMC2349985__F1 | Role of Leukotriene B4 Receptors in Rheumatoid Arthritis |
| PMC2358943__F1 | Metabolism of PtdIns(4,5)P2 by PLCG and PI3K |
| PMC2358953__F2 | Network diagram showing the checkpoint response to uncapped telomeres |
| PMC2359939__F9 | Proposed mechanism for RES induced apoptosis in LNCaP and PC-3 human prostate tumour cells |
| PMC2360215__F1 | Activation of the RAS–RAF–MEK pathway in thyroid cancer |
| PMC2360352__F1 | Schematic depicting the central role of HER3 in mediating PI3K/Akt signalling downstream of the HER family |
| PMC2360544__F2 | Novel therapeutic targets and proposed mechanisms of androgen resistance (text in red) in hormone refractory prostate cancer |
| PMC2360674__F8 | Schematic of porphyrin-synthetic pathway to illustrate potential control points for increased PpIX accumulation |
| PMC2361115__F1 | Cytoplasmic/traditional and nuclear modes of the EGFR signalling pathway |
| PMC2361340__F5 | Differential targets of copy number-induced expression changes in key biochemical pathways between SCLC and NSCLC |
| PMC2364238__F1 | SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer. |
| PMC2366099__F1 | Folate and one-carbon metabolic pathway |
| PMC2373983__F1 | Human T-Cell Leukemia Virus Type 1 Blunts Signaling by Interferon Alpha |
| PMC2374452__F5 | Molecular pathways of rheumatoid arthritis-related cartilage destruction as reflected by the in vitro model |
| PMC2374589__F1 | Programmed cell death can be executed via extrinsic and intrinsic pathways depending on the stimulus leading to apoptosis |
| PMC2374711__F5 | Proposed model of APL pathogenesis induced by PML-RARA |
| PMC2374962__F2 | Regulation of glycolysis and fatty acid synthesis |
| PMC2375563__F1 | Muscle growth: no IGFs, ands, or buts |
| PMC2375600__F2 | From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy |
| PMC2376243__F8 | Schematic mechanism of AB oligomer-mediated aberrant PAK activation and translocation in Alzheimer disease pathogenesis |
| PMC2376838__F8 | LRG-Accelerated Differentiation Defines Unique G-CSFR Signaling Pathways Downstream of PU.1 and C/EBPE That Modulate Neutrophil Activation |
| PMC2377014__F10 | BDNF enhancement of glutamate-induced phase shifting in the SCN, and potential locations in the signaling pathway where ethanol could inhibit this process |
| PMC2383880__F1 | Manual layout of Type II interferon signalling (IFNG) taken from the integrated pathway diagram (Figure 2) |
| PMC2383880__F7 | A logic-based diagram of signalling pathways central to macrophage activation. |
| PMC2383925__F9 | MiRNA model for the molecular pathogenesis of recurrent ovarian cancer |
| PMC2384123__F8 | Possible model for CCL5-mediated mRNA translation in CD4+ T cells |
| PMC2386254__F11 | A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage |
| PMC2386284__F5 | The mechanism of retinoic acid stimulation of NIS expression by modifying signal transduction pathways in breast cancer and thyroid cells, based on the results of the inhibitor studies |
| PMC2386416__F1 | Illustrations of the 5 Alpha-reductase action and the pathway of androgen action on target gene expression |
| PMC2386920__F7 | IRF-5 in the innate antiviral response |
| PMC2387053__F2 | Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit? |
| PMC2387183__F4 | Autocrine/paracrine induction of osteogenesis in hMSCs by PKA signaling |
| PMC2390552__F11 | ERK1 and ERK2 knockdown differently affect signals involved in patterning of the early embryo |
| PMC2390552__F6 | Analysis of Nodal signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390552__F7 | Analysis of FGF signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390552__F8 | Analysis of Wnt signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390552__F9 | Analysis of BMP signaling processes in ERK1MO and ERK2MO gene expression profiles |
| PMC2390572__F10 | MCF10A Pathway 2 affected by TFIIS knockdown |
| PMC2390572__F8 | Major pathways affected by TFIIS knockdown in MCF7 |
| PMC2390572__F9 | MCF10A Pathway 1 affected by TFIIS knockdown |
| PMC2391069__F1 | Overindulgence and metabolic syndrome: is FoxO1 a missing link? |
| PMC2391280__F1 | A signaling pathway AKTing up in schizophrenia |
| PMC2393790__F3 | Citrate cycle genes are up-regulated in the brains of nurse bees |
| PMC2394659__F3 | Aged Retinal Pigment Epithelium/Choroid: A Potential Substratum for the Pathogenesis of Age-Related Macular Degeneration |
| PMC2394714__F10 | TGFB1-induced PAI-1 expression in VSMC |
| PMC2394752__F4 | Contextual organization of the NFKB positive modulators |
| PMC2394768__F4 | Network diagram comprising genes and functional processes associated with regulated AS events in the CNS |
| PMC2395050__F1 | PG-recycling pathway of the wild type (A) and trapping of anhMurNAc-tripeptide in an ampD mutant (B) |
| PMC2395193__F3 | Gene networks identified in both recEbo-VP35/WT- and recEbo-VP35/R312A-infected cells compared to mock-infected and irradiated controls |
| PMC2395337__F1 | 5-Fuorouracil drug pathway demonstrating the interaction of multiple gene products |
| PMC2396219__F2 | PPARA and AMPK activities in the cancer cells exposed to energetic stress |
| PMC2396493__F1 | P53 on the IGF-1 signaling pathway |
| PMC2396785__F2 | Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle |
| PMC2397440__F8 | Possible role of AICAR and compound C on the AMPK pathway and on glycolysis in CT-2A and astrocytes under low glucose conditions |
| PMC2398704__F3 | High and low pollen-hoarding strain bees |
| PMC239898__F6 | Activation of the MAPK signaling pathway by FSH, ATP and GnRH in ovarian cancer |
| PMC2405801__F2 | Description of possible involved signalling pathways |
| PMC2405914__F4 | Catenins: Keeping Cells from Getting Their Signals Crossed |
| PMC2408406__F1 | Microvasculature in the pathogenesis of inflammatory bowel disease |
| PMC2408433__F1 | Glucose transport regulation by the Akt/TSC pathway |
| PMC2408857__F6 | Signaling and bipolar cell reprogramming |
| PMC2408969__F8 | Deciphering the Ubiquitin-Mediated Pathway in Apicomplexan Parasites: A Potential Strategy to Interfere with Parasite Virulence |
| PMC2409614__F3 | Development of tamoxifen (TAM)-resistant breast cancer and the changing role of oestradiol (E2) in the life and death of ER-positive cancer cells |
| PMC2409816__F1 | Schematic representation of the major pathways of ganglioside biosynthesis |
| PMC2410042__F2 | Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival |
| PMC2410087__F1 | Example of EGFR-mediated signaling changes, a commonly disrupted pathway in lung cancer |
| PMC2410298__F1 | TOLL-LIKE RECEPTORS REGULATION OF VIRAL INFECTION AND DISEASE |
| PMC2413058__F7 | Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor |
| PMC2413267__F1 | Wnt Signaling and Skeletal Development |
| PMC2413330__F3 | Working hypothesis on the mechanism by which plasminogen activator inhibitor-1 (PAI-1) causes hepatic steatosis |
| PMC2417166__F8 | Wnt signaling pathways in INS-1 cells |
| PMC2417187__F7 | Activation of the UPR in the absence of H6PD |
| PMC2417189__F8 | Inhibition of neurogenesis and axis duplication by mkrn2 via PI3K/Akt signaling pathway |
| PMC2423292__F6 | Musashi1 signaling in mammary progenitor cell proliferation |
| PMC2423294__F8 | The PKD1/class II HDAC/MEF2 signaling pathway in skeletal muscle |
| PMC2423297__F9 | The role of cAMP-stimulated adipogenesis via PKA- end Epac1-dependent processes |
| PMC2423434__F5 | Dynamically asserted instances of interactions |
| PMC2423668__F1 | Two branches of TLR downstream signaling |
| PMC2424193__F6 | Chemical Rescue of ÃŽâ€F508-CFTR Mimics Genetic Repair in Cystic Fibrosis Bronchial Epithelial Cells |
| PMC2424235__F1 | Auxin signaling |
| PMC2424294__F2 | Induction and lifetimes of signal transduction proteins (and their mRNAs) at various positions in signal transduction networks |
| PMC2424295__F2 | Feedback loops in NFKB signaling |
| PMC2427336__F9 | A schematic summarizing ER stress response pathways in cells compensating for deficiency of the ER stress response kinase, PERK |
| PMC2427358__F8 | Summary of GRTH impact in apoptotic pathways in germ cells |
| PMC2430503__F1 | Resistance to ErbB-targeted cancer therapeutics |
| PMC2430594__F1 | Cartoon of two of the most promising DNA repair pathways for cancer therapeutics |
| PMC2430620__F1 | Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate |
| PMC2430694__F2 | Inflammatory Pain: The Cellular Basis of Heat Hyperalgesia. |
| PMC2430908__F8 | Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity |
| PMC2432084__F9 | p27Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells |
| PMC2432088__F1 | WNT SIGNALING PATHWAY: AGING GRACEFULLY AS A PROTECTIONIST? |
| PMC2433332__F3 | T-cell polarizing factors |
| PMC2435243__F9 | Several signaling pathways work together in the TGFB1-induced expression of CCN2/CTGF in primary human gingival fibroblasts |
| PMC2435278__F2 | The Aedes aegypti Toll Pathway Controls Dengue Virus Infection |
| PMC2435380__F1 | Methionine metabolic pathway |
| PMC2435382__F11 | Hypothetical scheme illustrates the putative intracellular signaling cascades serving as the context for the data collected in the current study |
| PMC2435603__F8 | Potentiation of Nerve Growth Factor-Induced Neurite Outgrowth by Fluvoxamine: Role of Sigma-1 Receptors, IP3 Receptors and Cellular Signaling Pathways |
| PMC2435618__F2 | Pathways involved in cell differentiation, homeostasis and apoptosis in the adult intestinal epithelium, Beta-catenin and TCF4 are expressed in the proliferative compartment, where are located the intestinal epithelial stem cells |
| PMC2438299__F6 | Regulation of G1/S transition by the Cdh1/APC-Skp2-p27 cascade in colon cancer Cdh1/APC is critical in regulating Skp2-p27-cyclin E/CDK2 axis, resulting in averting abnormal entry of S phase |
| PMC2440410__F3 | Regulation of post-cushion valve maturation to thin fibrous leaflets also includes EGF receptor signalling in addition to differential signalling of the pathways in c |
| PMC2440498__F1 | Signaling cascades initiated via TLR2- and TLR4-dependent activation |
| PMC2441985__F3 | The regulation of the insulin signaling pathway by miRNA cluster mmu-mir-183-96-182 |
| PMC2442829__F1 | Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations |
| PMC2442829__F2 | Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations |
| PMC2442833__F1 | Metabolic network of oryza sativa L |
| PMC2443667__F1 | Connections between the SAM cycle, transsulfuration pathway, and glutathione production |
| PMC2443854__F1 | The Essential Components of Nodal SignalingTGFB proteins are synthesized as pre-pro-proteins requiring cleavage of the signal peptide (black) and prodomain (orange) prior to dimerization of active ligand (red diamonds) |
| PMC2446520__F1 | The GNB/LNB pathway and related enzymes |
| PMC2447903__F8 | TWEAK killing |
| PMC2448841__F5 | Proposed model of arrest of maturation/activation of DCs via ILT4 receptor and HLA-G ligand |
| PMC2453072__F3 | The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant |
| PMC2453100__F7 | The activated PI3K-AKT pathway and its downstream effectors that contribute to the tumorigenesis of TSHomas in TRBPV/PV mice |
| PMC2453756__F1 | Pathway of murine Th17 differentiation |
| PMC2455793__F1 | Interaction between two known Egr1 target genes, PTEN and fibronectin achieves a delicate balance between attachment and apoptosis of detached cells (anoikis) |
| PMC24579__F6 | Integration of tyrosine kinase signaling to both cAMP and MAPK 1,2 pathways, resulting in cell cycle arrest and the reduction of MAPK 1,2 triggered proliferation |
| PMC2464594__F4 | Oct-4 Targets in the Wnt Signalling Pathway |
| PMC2464747__F1 | Molecular mechanisms of androgen action |
| PMC2469272__F2 | LPS signaling [modified from O'Neill and Bowie () with permission] |
| PMC2474812__F1 | Classical and back-door pathways of androgen biosynthesis |
| PMC2474943__F4 | Points of action of flavonoids within JNK pathway |
| PMC2474943__F5 | Points of action of flavonoids within p38 pathway |
| PMC2474943__F7 | Points of action of flavonoids within PI3K/Akt signalling pathway |
| PMC2474948__F1 | Integration of the TGFB1 apoptotic signal by the lipid oxidation end-product 4-hydroxynonenal |
| PMC2475726__F10 | F igure 10.— |
| PMC2476215__F3 | Brick by brick: metabolism and tumor cell growth |
| PMC2477698__F1 | Examples of the molecular mechanisms by which phytochemicals activate hormetic stress response pathways |
| PMC2480606__F1 | An outline of major signaling pathways leading to NFKB activation |
| PMC2480606__F2 | NFKB pathway in skeletal muscles |
| PMC2481274__F2 | Type I Interferon: Potential Therapeutic Target for Psoriasis? |
| PMC2483283__F2 | Coexpression of genes within three core metabolic pathways |
| PMC2483283__F4 | Coexpression of the genes for fatty acid biosynthesis |
| PMC2483283__F5 | Leucine degradation pathway in mitochondria |
| PMC2483757__F1 | Kinetic model of the EpoR/GATA-1 network implicated in erythrocyte progenitor commitment |
| PMC2484121__F2 | Small Integrin-Binding LIgand N-linked Glycoproteins (SIBLINGs): Multifunctional proteins in cancer. |
| PMC2490739__F8 | Scheme summarizing the differential effect of PARP-1 inhibition versus silencing on SSB repair via the BER pathway |
| PMC2490815__F3 | Regulation of NFKB pathway by PPAR agonists in CNS diseases |
| PMC2490815__F4 | IL-12, IL-23 and IL-27 are heterodimeric cytokines signals through Jak-Stat pathway and induce Th1/Th17 differentiation and T-bet expression in T cells |
| PMC2491599__F2 | Wnt canonical signaling pathway |
| PMC2491599__F3 | Wnt signaling pathwhay in cervical cancer |
| PMC2491602__F6 | TNFA signaling pathway |
| PMC2491640__F5 | Regulatory network of important genes involved in EBV-dependent NPC |
| PMC2491704__F3 | Recycling pathway of acetylcholine (ACh) synthesis, release, action and breakdown at a cholinergic nerve terminal |
| PMC2491722__F4 | Gdnf signaling pathways within the mammalian spermatogonial stem cell niche |
| PMC2491722__F6 | Gdnf signaling pathways within the mammalian spermatogonial stem cell niche |
| PMC2492871__F4 | Networks top-ranked by Ingenuity Pathway analysis after knockdown of TP53 (A) and LSR1+TP53 (B) |
| PMC2492871__F5 | Networks top-ranked by Ingenuity Pathway analysis after knockdown of LSR1 (A-B) |
| PMC2492871__F6 | Networks top-ranked by Ingenuity Pathway analysis after knockdown of LSR2 (A-B) |
| PMC2493210__F1 | Schematic diagrams of small intestine mucosa in normal and infected intestines |
| PMC2494567__F10 | Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure |
| PMC2494582__F1 | Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus |
| PMC2494808__F3 | Graphical representation of connections between receptors and pathways implicated in NTS baroreflex modulation by pharmacological studies |
| PMC2494844__F2 | Genomic dissection of the cytokine-controlled STAT5 signaling network in liver |
| PMC2495063__F3 | Germline Mutations and Variants in the Succinate Dehydrogenase Genes in Cowden and Cowden-like Syndromes. |
| PMC2496917__F1 | Interfering the PI3K/mTOR/p70S6K signaling pathway |
| PMC2500163__F4 | HIV Replication Enhances Production of Free Fatty Acids, Low Density Lipoproteins and Many Key Proteins Involved in Lipid Metabolism: A Proteomics Study |
| PMC2504032__F8 | Mechanism for the Inhibition of Neural Progenitor Cell Proliferation by Cocaine |
| PMC2504760__F1 | Mechanisms by which diabetes increases cardiovascular disease |
| PMC2515131__F2 | Signal transduction events initiated by Kit and FcERI leading to specific mast cell responses, and the integration of these pathways for the synergistic enhancement of mast cell mediator release |
| PMC2515306__F1 | Wnt signaling pathway and its inhibition by AB aggregates |
| PMC2515336__F2 | Representation of the two NFKB signaling pathways |
| PMC2515553__F1 | Ischemic Preconditioning And Myocardial Infarction: An Update and Perspective |
| PMC2515871__F2 | Roles of cis- and trans-Changes in the Regulatory Evolution of Genes in the Gluconeogenic Pathway in Yeast |
| PMC2516358__F7 | Time ordered sequential events control cellular decision of migration |
| PMC2516423__F1 | The control of erythropoietin synthesis by the oxygen sensing pathway.In the presence of oxygen HIFalpha is hydroxylated by the prolyl hydroxylase PHD2 and once modified the von Hippel Lindau (VHL) protein is able to bind |
| PMC2516940__F2 | Sepsis and insights from clinical trials |
| PMC2516985__F8 | Cross-talk pathway in RSV infection |
| PMC2517145__F1 | PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells |
| PMC2517296__F1 | The co-ordinated activation of pro-inflammatory signalling pathways by TLR ligands and the pro-inflammatory cytokines TNFA, IL-1 and IFN |
| PMC2517590__F2 | Schematic overview of the integrin signaling |
| PMC2517664__F2 | A simplified diagram of the key type-1 cytokine/receptor interactions relevant for immunity against intracellular bacteria, derived from published gene knockout mouse studies |
| PMC2517702__F3 | Signal transduction in the CD95 pathway |
| PMC2517789__F1 | Cytokines and their receptors in cardiovascular diseases |
| PMC2517789__F2 | Two pathways from gp130 to hypertrophic gene expression |
| PMC2518073__F8 | Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer |
| PMC2518078__F1 | Cotargeting survival signaling pathways in cancer |
| PMC2518081__F3 | The pathways involved in polycystic kidney disease |
| PMC2518463__F2 | Binding of specific signalling proteins to phosphorylated tyrosine residues on KIT following receptor activation and the subsequent signalling events leading to mast cell responses |
| PMC2518924__F9 | The CEBPD network |
| PMC2519092__F2 | Cellular responses after six hours exposure to L |
| PMC2519122__F1 | Role of mTOR in anticancer drug resistance |
| PMC2519541__F2 | Integration of the AinS-AinR and LuxI-LuxR quorum sensory pathways |
| PMC2519632__F6 | Proposed model of KSHV-induced lymphatic reprogramming of endothelial cells |
| PMC2522268__F1 | Interferon-inducible antiviral effectors |
| PMC2522278__F2 | Comparative Analysis of mRNA Targets for Human PUF-Family Proteins Suggests Extensive Interaction with the miRNA Regulatory System |
| PMC2525561__F4 | Schematic diagram of in vivo n3 VLC-PUFA biosynthetic pathway mediated by ELOVL4 and other ELO families [modified after Suh and Clandinin ()] |
| PMC2526691__F2 | Focal adhesion pathway interaction map |
| PMC2527273__F2 | The signaling pathway of Type II, FasL signaling-induced apoptosis, adapted from Bagci et al |
| PMC2527618__F4 | Graphic illustrating the roles of 8 genes implicated in the present study in lithium-sensitive signaling pathways |
| PMC2528242__F1 | Peroxisome proliferator-activated receptorG and ligands: pathways and functions |
| PMC2528845__F2 | Intracellular signaling activated through FGFRs |
| PMC2528845__F4 | Opposing signals regulate sex determination in the bipotential gonad |
| PMC2528847__F2 | Integration of genomic and nongenomic/rapid ER signaling and its crosstalk with growth factor receptor and cell kinase pathways in endocrine resistance: a working model |
| PMC2528859__F2 | The UPR sensors PERK, IRE1A, and ATF6 control mRNA translation and transcriptional induction of UPR-regulated genes |
| PMC2529154__F4 | Four components to yield MDP chromophore |
| PMC2529314__F7 | Interactions of KEGG pathways for differentially expressed genes in different stages of PAD |
| PMC2529314__F8 | Over-representation of Toll-like receptor signaling pathway genes |
| PMC2530034__F1 | Transcriptional regulation and the pathway of RNA polymerase II transcription |
| PMC2531163__F3 | Developmental signaling pathways |
| PMC2533023__F5 | Response of A549 cells exposed to crocidolite |
| PMC2533092__F1 | Metabolic pathways for the synthesis of phospholipids and neutral lipid classes in S |
| PMC2533145__F10 | Rap1 and glycolytic/TCA cycle reaction |
| PMC2533280__F1 | Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood |
| PMC2533786__F9 | PI 3-kinase/AKT-dependent pathways involved in IL-1 induction of IL-6 |
| PMC2533793__F10 | Model for negative regulation of Wnt signaling pathway by corepressors SMRT and NCoR |
| PMC2536507__F2 | Pathogen recognition systems |
| PMC2536824__F4 | Ingenuity Pathway Analysis (IPA) of genes specifically overexpressed in B1-Arg389 transgenic mouse hearts |
| PMC2536868__F7 | Pathways for major lipid metabolism |
| PMC2537559__F3 | Glycolysis pathway |
| PMC2537559__F4 | Alterations in extraceullular matrix and secreted proteins associated with metastatic cancer |
| PMC2537559__F5 | Alterations in adhesion-mediated signaling and cytoskeleton remodeling in metastatic cancer |
| PMC2537575__F5 | NFKB canonical signaling pathway from IPA |
| PMC2538513__F2 | The involvement of death receptor pathway (right half) and mitochondrial pathway mediated (left half) apoptosis in nurse cell formation |
| PMC2538513__F4 | Schematic illustration of the involvement of c-Ski and TGFB signaling pathway in nurse cell formation |
| PMC2538516__F1 | Biosynthetic relationships between amino acids, as defined by their biosyntheses and their relationships with the glycolytic pathway and the citric acid cycle |
| PMC2542903__F6 | Proposed EphB2 signaling network |
| PMC2543934__F5 | PPARG in Type 1/Type 2 T (NK) cell differentiation |
| PMC2546860__F2 | Glycerol biosynthesis and other major pathways contributing to cytosolic NAD+/NADH balance in S |
| PMC2546905__F4 | Predicted targets of miR-100 and miR-101 in the 3′-UTR of members of the mTOR pathway |
| PMC2546909__F1 | Signal transduction pathway elicited by Env interaction with CCR5 required for Rac-1 activation and membrane fusion |
| PMC2547860__F6 | Networks among genes involved in milk fat synthesis |
| PMC2547880__F6 | Average rate constants and flux distribution of apo B lipoproteins in response to the diet high in complex carbohydrate (CHO diet; A) and in response to the diet high in monounsaturated fat (MUFA diet; B) in 12 subjects |
| PMC2548289__F1 | Hereditary Hemochromatosis in the Post HFE Era |
| PMC2552992__F9 | Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease |
| PMC2553363__F1 | Extrinsic and intrinsic pathways of hepatocyte apoptosis |
| PMC2553363__F2 | ER stress pathway |
| PMC2553572__F2 | DSB repair pathways |
| PMC2553712__F1 | Design, Synthesis and Characterization of A Potent, Non-Peptide, Cell-Permeable, Bivalent Smac Mimetic that Concurrently Targets both the BIR2 and BIR3 Domains in XIAP |
| PMC2556095__F4 | TGFBeta-related signalling pathway controlling Myc activity in keratinocytes |
| PMC2556095__F6 | In the canonical TGFB signalling pathway, ligands signal through type I and II transmembrane protein kinase receptors |
| PMC2556249__F2 | Insulin receptor signaling |
| PMC2556276__F1 | Display of differentially expressed genes in the uterine cervix after term spontaneous labor mapped on the PLAU signaling pathway |
| PMC2556568__F2 | Molecular processes that handle – and mishandle – dietary lipids |
| PMC2556866__F1 | Telomere structure and DSB processing |
| PMC25571__F9 | A model of cnxPg action |
| PMC2559887__F2 | Ingenuity pathway analysis on AP-1 related gene network |
| PMC2559887__F3 | Ingenuity pathway analysis on NFKB related gene network |
| PMC2559911__F7 | Model for the function of SHC-1 in IIS and JNK signaling |
| PMC2561291__F1 | Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions |
| PMC2561291__F5 | Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions |
| PMC2561962__F1 | Ischemia induces cell death by several distinct pathways, and Hsp70 reduces all of these |
| PMC2562925__F8 | Schematic depicting the roles of p53 and wnt7b in proposed pathway for NGF-mediated neurite outgrowth in PC12 differentiation |
| PMC2562939__F1 | The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin |
| PMC2563180__F3 | The cardiofaciocutaneous syndrome |
| PMC2563957__F1 | Phospholipase A2 (PLA2) catalyzes phosphatidylcholine into AA in response to agonist stimulation of a G-protein–coupled cell surface receptor |
| PMC2564730__F3 | Use of MIMO models to infer regulatory interactions in breast cancer cells |
| PMC2564829__F7 | Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells |
| PMC2564980__F5 | Genes with differential expression in the carcinoma and papillary adenocarcinoma tumors were assembled into distinct metabolic pathways |
| PMC2564980__F7 | Higher expression of genes involved in O-glycan synthesis in the carcinoma compared to the papillary adenocarcinoma tumors |
| PMC2565686__F6 | Merger of the interaction maps for the three human proteins ING1, MEKK, and p38a (p38MAPK) based on empirical data retrieved from the STRING database |
| PMC2566006__F2a | A Defect in Menadione Biosynthesis Induces Global Changes in Gene Expression in Staphylococcus aureus . |
| PMC2566525__F8 | Schematic view of part of the IGF-1 and integrin signaling pathway genes transcribed by hNCC |
| PMC2566927__F2 | Essence of retrograde signaling in model organisms |
| PMC2567351__F1 | T Cell Receiptor Signaling Pathway |
| PMC2567351__F2 | MAPK Signaling Pathway |
| PMC2567408__F8 | NCAM upregulation leads to a functional switch |
| PMC2567511__F1 | The tetrapyrrole pathway in plants showing intermediates and genes analyzed in this study |
| PMC2570214__F8 | Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2-/- Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM |
| PMC2570299__F3 | Role of GalGlyNAcPVv in V |
| PMC2570545__F2 | EGFR signalling pathway in lipid rafts |
| PMC2570554__F4 | Anti-apoptotic mechanism of survival and growth of serum-starved 5637 human bladder carcinoma cells |
| PMC2570606__F6 | Proposed model for the effects of hypoxia-induced energy stress on them TOR pathway in HNSCC cells |
| PMC2570700__F1 | MOLECULAR TARGETED THERAPIES FOR PANCREATIC CANCER |
| PMC2571037__F1 | Anticancer therapy: boosting the bang of Bim |
| PMC2572128__F1 | Simplified model of translation initiation |
| PMC2572856__F1 | Aging of signal transduction pathways, and pathology |
| PMC2572865__F1 | Hematopoietic niche and bone meet |
| PMC2573957__F1 | Association of Interacting Genes in the Toll-Like Receptor Signaling Pathway and the Antibody Response to Pertussis Vaccination |
| PMC2574011__F1 | Store-operated Ca2+ entry in T cells |
| PMC2574638__F8 | Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer’s Disease |
| PMC2574672__F2 | Iron-sulfur (Fe-S) cluster biogenesis in eukaryotes |
| PMC2574814__F7 | Oxysterol-Induced Osteogenic Differentiation of Marrow Stromal Cells is Regulated by Dkk-1 Inhibitable and PI3-Kinase Mediated Signaling |
| PMC2574839__F2 | Androgen synthesis pathway and therapeutic targets |
| PMC2574996__F12 | We then examined the Pd-catalyzed oxidative kinetic resolution of hydroxyester (±)-15 |
| PMC2574996__F15 | Our difficulty in suppressing epimerization at the bis-benzylic stereocenter bearing the ester in the azide displacement led us to pursue an alternate route to amurensinine via intermediates with attenuated acidity at the bis-benzylic carbon () |
| PMC2575183__F7 | Proposed signaling mechanism that stimulates EMT |
| PMC2575400__F2 | MiRNA Signature of Prion Induced Neurodegeneration |
| PMC2575467__F5 | A model of KCNQ1/KCNE1 function in embryogenesis |
| PMC2575513__F2 | Diversification of the innate immune arsenal in amphioxus |
| PMC2575530__F2 | Insulin-like growth factor-I signaling pathway involved in breast cancer |
| PMC2575612__F3 | Inter-individual mRNA expression variances in the transforming growth factor-beta (TGFB) signaling pathway in rheumatoid arthritis (RA) compared with normal control (NC) |
| PMC2575612__F4 | Inter-individual mRNA expression variances in the mitogen-activated protein kinase (MAPK) signaling pathway in rheumatoid arthritis (RA) compared with normal control (NC) |
| PMC2575629__F3 | Alternative pathway of NFKB activation |
| PMC2575728__F2 | Following the cytokine signaling pathway to leukemogenesis: a chronology |
| PMC2575803__F1 | Most prominently involved biological pathways in OSCC |
| PMC2575825__F4 | Glutathionine (GSH) redox network |
| PMC2575825__F9 | Redox-sensitive steps in hypothetical redox signaling pathways |
| PMC2575845__F1 | RLR signaling pathway and its negative regulatory molecules |
| PMC2575905__F1 | Current concepts of the amino acid signaling pathway leading to protein synthesis |
| PMC2576041__F9 | The role of the IGF-1/phosphatidylinositol 3-kinase (PI3K)/Akt pathway and atrogin-1 and MuRF-1 in SI-induced atrophy and in the amelioration of atrophy by high-load isometric contractions |
| PMC2576557__F10 | Schematic diagram showing the pathway involved in high glucose- and high insulin-induced extracellular matrix protein synthesis mediated by GSK3B and eIF2BE |
| PMC2576563__F7 | Tight regulation of MUC5AC mucin induction by pneumolysin via PAK4-JNK and MKP1 signaling pathways |
| PMC2577004__F1 | Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-ALL |
| PMC2577137__F1 | Cross talk between PKA, PI3K/AKT and WNT/CTNNB1 intracellular signaling pathways |
| PMC2577427__F9 | Model depicting signaling pathways for TPR-mediated modulation of OLG development and function |
| PMC2577435__F9 | Signaling from LMP1 and TLR to IRF7 activation |
| PMC2577687__F1 | Metabolic scheme |
| PMC2577715__F15 | Notch, Wnt, and SHH signaling pathways |
| PMC2577715__F4 | NFKB signaling and MDR gene expression |
| PMC2577715__F9 | Nrf2 and transcriptional regulation of Gamma-GCSh expression |
| PMC2577730__F6 | Influenza A Virus Inhibits Alveolar Fluid Clearance in BALB/c Mice |
| PMC2577794__F1 | Uncovering cryptic genetic variation in C |
| PMC2578840__F8 | Proposed signaling pathway |
| PMC2579334__F3 | Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure |
| PMC2579774__F4 | HIV-1 infected astrocytes and the microglial proteome |
| PMC2581553__F7 | The PpsB product and the proposed interaction between the PDIM and FAS-II pathways |
| PMC2581573__F1 | The IL-1 signaling pathway |
| PMC2581748__F2 | Activation of the mammalian target of rapamycin (mTOR) pathway can result from numerous glioma-associated genetic changes |
| PMC2581764__F3 | Roles of lipid peroxidation products in cytoprotective response of cell upon exposure to laminar shear stress |
| PMC2581770__F3 | TNFR and LTBR signaling pathways for NFKB activation |
| PMC2581785__F1 | Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum |
| PMC2581798__F3 | Information flow through the JNK network |
| PMC2582196__F2 | Classic renin-angiotensin-aldosterone system (RAAS) pathway and angiotensin II (Ang II)/insulin signaling in the vascular smooth muscle cell |
| PMC2582800__F1 | General scheme of insulin signaling |
| PMC2582809__F1 | Role of cytokines in DC and T-cell interactions |
| PMC2582888__F8 | Two parallel pathways are required for Abl-dependent cell detachment |
| PMC2583327__F10 | Transcriptional and Translational Regulation of Transforming Growth FactorB Production in Response to Apoptotic Cells |
| PMC2583357__F1 | ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY |
| PMC2583357__F3 | ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY |
| PMC2583496__F2 | Global regulation of the E |
| PMC2583931__F1 | Migrating D-loop model of recombination |
| PMC2584013__F23 | TNF-induced and ROS-dependent events in target cells: the role of JNK activation in mediating cell death |
| PMC2584013__F25 | ER stress and ROS in NAFLD/NASH |
| PMC2584165__F2 | Highly simplified diagram of signaling pathways involving Beta-catenin that may be relevant for RPE cell morphogenesis and susceptibility to age-related oxidative stress |
| PMC2584809__F6 | Schematic model illustrating constitutive vs |
| PMC2585009__F4 | HIV-1 Activates Macrophages Independent of Toll-Like Receptors |
| PMC2585009__F7 | HIV-1 Activates Macrophages Independent of Toll-Like Receptors |
| PMC2585593__F1 | Diagrammatic representation of pathways associated with aroma production and links to associated metabolic activities |
| PMC2585609__F1 | A schematic representation of the functional domains of Stim and Orai proteins |
| PMC2586079__F1 | COMPLEMENT ACTIVATION FRAGMENT Bb IN EARLY PREGNANCY AND SPONTANEOUS PRETERM BIRTH |
| PMC2586109__F1 | Protein kinase C isozymes as therapeutic targets for treatment of human cancers |
| PMC2586270__F6 | Furin action in pituitary gonadotrope cells |
| PMC2586335__F1 | Ras signalling pathways |
| PMC2586899__F4 | The involvement of TNFAlpha-mediated signaling pathways in insulin resistance |
| PMC2586935__F4 | TGFB pathway as affected by IGF2 administration based on Pathway-Express |
| PMC2587085__F1 | Targeting EGFR and Src Pathways in Head and Neck Cancer |
| PMC2587278__F1 | Oxidative and alkylation DNA damage is effectively repaired by the DNA BER pathway |
| PMC2587303__F1 | mTOR inhibition as a Therapeutic Strategy in the Management of Urologic Malignancies |
| PMC2588608__F2 | Pathway Annotation and Summary Hit Table |
| PMC2590699__F1 | Current model for Okazaki fragment maturation |
| PMC2592633__F1 | RNAi pathways in Drosophila |
| PMC2592774__F1 | TLR signalling pathways |
| PMC2592794__F1 | Monosodium urate (MSU) crystals activate monocytes via the Toll-like receptor (TLR) pathway and the inflammasome |
| PMC2592809__F9 | Scheme summarises different intracellular pathways during osteoblast differentiation which include promoting (blue) and inhibiting (red) factors and are mainly mediated by Smad proteins |
| PMC2593006__F3 | Signalling pathways underlying neuronal survival and cognitive performance |
| PMC2593012__F2 | Gene expression data mapped on the Mus musculus fatty acid synthesis pathway |
| PMC2593012__F3 | Gene expression data mapped on the mouse insulin signaling pathway |
| PMC2593023__F1 | Unexpected pieces to the senescence puzzle |
| PMC2593077__F2 | Hepatitis C and Innate Immunity - Recent Advances |
| PMC2593123__F1 | A simplified schematic of the core left-right signaling pathway in the e8.5 (6 somite) mouse embryo |
| PMC2593438__F7 | AKT reduces the growth-inhibitory function of TGFB1 |
| PMC2593440__F3 | Network of differentially expressed genes in the cell cycle control pathway in sorted R1/R2 Eklf-/- E13.5 fetal liver cells |
| PMC2593475__F1 | PI3K/PTEN/Akt/mTOR Pathway |
| PMC2593508__F8 | Fasudil inhibits the myogenic response in the fetal pulmonary circulation |
| PMC2593565__F3 | Epithelial barrier function by lactobacilli |
| PMC2593566__F3 | JAK/STAT signaling pathway and SARS-CoV |
| PMC2593676__F6 | Gene expression and metabolite levels in the distal network pathways related to Met- and Trp-derived GS biosynthesis |
| PMC2594010__F2 | Regulation of metastasis in colorectal adenocarcinoma: A collision between development and tumor biology |
| PMC2596245__F3 | EET- or sEHI-mediated antihyperalgesia occurs through 2 distinct mechanisms |
| PMC2596750__F8 | TNFR1 and LTBR ligation-induced signaling in vascular EC |
| PMC2596919__F2 | Obesity and Free Fatty Acids (FFA) |
| PMC2597184__F2 | Nuclear Factor-kappa B Signaling in Skeletal Muscle Atrophy |
| PMC2597223__F1 | Pathways of apoptosis |
| PMC2597498__F2 | TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway |
| PMC2597498__F4 | TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway |
| PMC2597730__F7 | Cascade between VEGFA, a direct target of BP1, and its downstream target genes in cell proliferation |
| PMC2597811__F1 | Molecular Genetics of Colorectal Cancer: An Overview |
| PMC2597859__F1 | Role of Programmed Cell Death in the Immunopathogenesis of Sepsis |
| PMC2600462__F5 | Morphoproteomic Evidence of Constitutively Activated and Overexpressed mTOR Pathway in Cervical Squamous Carcinoma and High Grade Squamous Intraepithelial Lesions. |
| PMC2600469__F4 | Genes regulated by SHP in PPAR signaling pathway |
| PMC2600644__F4 | Pathway schematic of significantly regulated genes in (A) NFKB signalling and (B) MAP kinase signalling |
| PMC2600878__F6 | Syk signaling is necessary for E-selectin-induced LFA-1-ICAM-1 association and rolling but not arrest |
| PMC2601639__F1 | Membrane Recruitment as a Cancer Mechanism: A Case Study of Akt PH Domain |
| PMC2601664__F1 | Membrane-initiated Estrogen Signaling in Hypothalamic Neurons. |
| PMC2601665__F1 | Hh-Gli pathway and the Gli code in tissue patterning and stem-cell lineages |
| PMC2603035__F3 | Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease |
| PMC2603135__F5 | Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data |
| PMC2603135__F6 | Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data |
| PMC2603427__F5 | Hierarchical layout of the EGFR1 pathway downloaded from the HPRD pathway database [] |
| PMC2603427__F6 | Hierarchical layout of the B-cell receptor pathway downloaded from the HPRD pathway database [] |
| PMC2603471__F1 | Ageing, oxidative stress and cancer: paradigms in parallax |
| PMC2603552__F10 | Role of oxysterol sulfation in lipid metabolism |
| PMC2604897__F2 | Putative biochemical pathways involving MGAT3 |
| PMC2605486__F3 | Progressive changes in progenitor cells during motor neuron development |
| PMC2605486__F4 | Olig2 and the transcription factor network controlling motor neuron differentiation |
| PMC2605487__F2 | Signalling pathways involved in the induction of astrocyte specification/differentiation |
| PMC2605641__F2 | Nrf2-ARE Pathway: An Indicator and Modulator of Oxidative Stress in Neurodegeneration |
| PMC2605957__F7 | Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway |
| PMC2606015__F9 | Schematic view of the Vav family-regulated signaling pathways of DT40 B-cells |
| PMC2606944__F9 | Role of Small GTPases and AvB5 Integrin in Pseudomonas aeruginosa–Induced Increase in Lung Endothelial Permeability |
| PMC2607021__F4 | Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease |
| PMC2607114__F1 | TFPI anti-coagulant and anti-inflammatory activities |
| PMC2607479__F1 | Comparing and Contrasting the Roles of AMPK and SIRT1 in Metabolic Tissues |
| PMC2610122__F1 | Classical view of three independent Wnt signalling pathways |
| PMC2610259__F1 | Chronic colon colitis model |
| PMC2610366__F1 | Pathways involved in folate-dependent methionine transmethylation and transsulfuration |
| PMC2610675__F6 | Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells |
| PMC2612083__F1 | Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder |
| PMC2612524__F7 | A potential model for contributions of F-BAR-containing adaptor proteins and PTKs in regulating FcɛRI signaling during internalization |
| PMC2612755__F5 | A theoretical pancreatic endocrine tumor cell, smooth muscle cell (pericyte) or endothelial cell demonstrating the sites and mechanism of action of novel agents for the management of metastatic PETs |
| PMC2612938__F2 | Pathways by which Mgrn1-mediated ubiquitination could modulate melanocortin receptor regulation of pigment production and energy metabolism |
| PMC2613033__F1 | Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study |
| PMC2613125__F6 | Interleukin-6 and Neural Stem Cells: More Than Gliogenesis. |
| PMC2613471__F1 | Revisiting Notch in remyelination of multiple sclerosis lesions |
| PMC2613484__F3 | Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways |
| PMC2613484__F7 | Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways |
| PMC2613883__F1 | Simplified schematic drawing of the TGF-Beta-Smad pathway |
| PMC2613930__F4 | Genes that contain the 100 most differentially methylated CpG sites between normal and lung cancer tissue samples (p-value < 0.005) |
| PMC2614485__F6 | A simplified Hh signaling pathway, constructed from combined Drosophila and mammalian data |
| PMC2615236__F1 | Regulation of IGF-I Function by Proinflammatory Cytokines: At the Interface of Immunology and Endocrinology |
| PMC2615463__F1 | Arc function in mGluR-LTD |
| PMC2615542__F2 | Luteolin, a flavonoid with potentials for cancer prevention and therapy |
| PMC2615558__F4 | Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus |
| PMC2617762__F6 | Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia |
| PMC261890__F8 | T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression |
| PMC2620272__F4 | Bimodal genes that were switched "on" as a result of HIV infection in KEGG T-cell receptor signalling pathways |
| PMC2621116__F2 | Representative plasmids used in this study |
| PMC2623309__F1 | Multiple feedback loops of p53 pathway |
| PMC2624576__F1 | Alternative splicing in the NFKB signaling pathway |
| PMC2626169__F1 | A simplified view of the sex-determination pathway in XX animals (A) and XO animals (B) |
| PMC2627520__F2 | Biosynthesis of Natural and Hyperelongated Chondroitin Sulfate Glycosaminoglycans: New Insights into an Elusive Process |
| PMC2627788__F5 | Wnt/Beta-catenin signaling pathway in leukemia |
| PMC2627792__F11 | Proposed pathway |
| PMC2627893__F2 | GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments |
| PMC2628375__F7 | Hypothetical scheme of activation of the murine Hamp1 promoter |
| PMC2628394__F15 | Biological network representing the schizophrenia p-value ranking |
| PMC2628394__F16 | Biological network representing the bipolar disorder p-value ranking |
| PMC2629585__F7 | Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response |
| PMC2629979__F1 | Molecular Mechanisms in COPD pathogenesis and potential therapeutic targets |
| PMC2630276__F7 | Model for the role of Hedgehog in the recovery of the BMP4-dependent stress erythropoiesis pathway in the spleen |
| PMC2630373__F1 | Regulation of G1/S transition by growth factor (insulin and IGF-I) signaling in Beta-cells |
| PMC2630379__F2 | FoxO proteins employ multiple signal transduction pathways that affect cell proliferation, survival and immune system function |
| PMC2630471__F5 | DAF-2 Insulin-like Signaling Pathway Independently Regulates Aging and Immunity |
| PMC2631022__F1 | ECM-receptor interaction pathway enriched by human switch-like genes |
| PMC2631022__F2 | KEGG Focal adhesion pathway enriched by human switch-like genes |
| PMC2631033__F1 | Tumor necrosis factor and cancer, buddies or foes? |
| PMC2631307__F1 | Glucocorticoids and neonatal brain injury: the hedgehog connection |
| PMC2631308__F1 | Insulin resistance |
| PMC2631376__F3 | Hypothalamic Malonyl-Coenzyme A and the Control of Energy Balance. |
| PMC2631402__F4 | The Legionella pneumophila replication vacuole: making a cozy niche inside host cells |
| PMC2631405__F1 | Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models |
| PMC2631600__F1 | The HMGCR pathway |
| PMC2632675__F3 | Cell cycle pathways in S |
| PMC2633067__F2a | Beyond Good and Evil in the Oral Cavity: Insights into Host-Microbe Relationships Derived from Transcriptional Profiling of Gingival Cells |
| PMC2633249__F3 | Enzymatic function of multiple origins regulates the progression of colorectal cancer and the development of metastases |
| PMC2633299__F11 | UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes |
| PMC2633398__F9 | An epistatic pathway and genetic model for replication slowing in fission yeast |
| PMC2633485__F8 | Proposed mechanism of PDGF signaling in the lens epithelial cells |
| PMC2633625__F2 | Toll-like receptors in skin |
| PMC2633716__F1 | Genetic Variation in Calcium Sensing Receptor (CASR) and Risk of Colon Cancer |
| PMC2634101__F1 | Model summarizing some of the pathways described in this review leading to chemotaxis and cell motility |
| PMC2634254__F2 | Embryonic liver development |
| PMC2634254__F4 | Upstream regulators and downstream targets of Beta-catenin during embryonic liver development |
| PMC2634257__F1 | Simplified schemes of the three Wnt signaling cascades |
| PMC2634657__F2 | Leptin Neuroprotection in the Central Nervous System: Mechanisms and Therapeutic Potentials |
| PMC2634670__F1 | Strategies to inhibit the VEGF signalling pathway |
| PMC2634812__F3 | Stepwise respecification of ETP and DN2 cells by GATA-3 overexpression |
| PMC2634812__F4 | Myeloid diversion pathways for advanced pro-T cells by re-introduction of C/EBPA or PU.1 |
| PMC2634812__F5 | Schematic of counterbalancing and dose-dependent regulatory forces that act on T-cell precursors through the ETP and DN2 stages |
| PMC2634840__F1 | Qualitative network showing mutual antagonism between AKT and p53 |
| PMC2634968__F2 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling. |
| PMC2634968__F5 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling |
| PMC2634968__F6 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling |
| PMC2634968__F7 | Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling |
| PMC2634987__F1 | The GEP100-Arf6 pathway to invasion |
| PMC2635018__F1 | Amino acid transporters and nutrient sensing mechanisms |
| PMC2635020__F1 | CATHEPSIN D - MANY FUNCTIONS OF ONE ASPARTIC PROTEASE |
| PMC2635127__F1 | Erk non-Smad pathway |
| PMC2635127__F2 | JNK/p38 non-Smad pathway |
| PMC2635127__F3 | Small GTPase non-Smad pathway |
| PMC2635127__F4 | PI3K/Akt non-Smad pathway |
| PMC2635340__F2 | Kinetic Scheme for the 5-HT1AR and 5-HT2AR mediated MAP kinase activation pathway |
| PMC2635620__F2 | Inhibition of each signaling molecules by natural products in insulin signaling |
| PMC2635670__F1 | Apoptosis pathways: The extrinsic or death receptor pathway (left) is triggered by members of the death receptor superfamily such as Fas |
| PMC2636986__F1 | Adaptor protein containing pleckstrin homology (PH) domain, phosphotyrosine-binding (PTB) domain, and leucine zipper motif (APPL1)-mediated adiponectin and insulin-signaling pathways |
| PMC2637179__F2 | Role of IRS-1 in insulin and IGF-1 signaling |
| PMC2637184__F1 | New central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9 |
| PMC2637474__F7 | Hypothetical pathway involved in general cerebellum-mediated motor learning |
| PMC2637482__F2 | Crosstalk between Robo4/Slit2 and VEGF signaling pathways |
| PMC2637651__F3 | Transcriptomes in Healthy and Diseased Gingival Tissues |
| PMC2637758__F5 | Pathways and networks associated with HSPA9, PHB, and ABCB6 |
| PMC2637783__F1 | Toll-like receptor (TLR) signaling |
| PMC2637898__F2 | EGFR signaling pathways |
| PMC2637898__F3 | EGFR signal transduction pathways |
| PMC2637898__F4 | VEGF signaling pathways |
| PMC2638772__F9 | Model whereby increased Fgfr3 signaling in chondrocytes causes premature synchondrosis closure and unification of ossification centers |
| PMC2639036__F1 | Single-strand break repair pathways |
| PMC2639448__F1 | Intrafollicular predictors and regulators of oocyte quality within the oocyte-somatic cell regulatory loop |
| PMC2639705__F9 | Two Chromogranin A-Derived Peptides Induce Calcium Entry in Human Neutrophils by Calmodulin-Regulated Calcium Independent Phospholipase A2 |
| PMC2639747__F1 | Smad3 in TGFB-induced antiproliferative transcriptional responses |
| PMC2639747__F2 | Smad3 in TGFB-mediated proapoptotic transcriptional responses |
| PMC2639789__F9 | Summary diagram of E2 regulation of Wnt/Beta-catenin signaling pathway after cerebral ischemia and proposed role in E2 ischemic neuroprotection |
| PMC2640319__F1 | Insulin and amino acid signaling pathway leading to the stimulation of translation initiation |
| PMC2640456__F1a | Meta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes |
| PMC2640984__F3 | Distribution between short and long flap removal pathways |
| PMC2641000__F4 | Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary |
| PMC2642591__F1 | Retinoic acid dependent regulation of immune responses by dendritic cells and macrophages |
| PMC2642659__F2 | Visualization of molecular interaction and reaction networks in the KEGG database |
| PMC2642890__F2 | Posttranscriptional regulation of gene networks by GREs |
| PMC2643067__F1 | De novo purine biosynthesis pathway |
| PMC2643306__F1 | Structure-function relationships in methionine adenosyltransferases |
| PMC2643336__F3 | From the diet to the nucleus: Vitamin A and TGFB join efforts at the mucosal interface of the intestine |
| PMC2643928__F1 | Activation of the transcription factors IRF3 and NFKB in response to infection with a single-stranded RNA virus |
| PMC2643977__F4 | Proposed integrated model for local water transport inhibition by activation of P2Y2 and adenosine A1 receptors (A1R) in inner medullary collecting duct principal cell |
| PMC2644070__F2 | Homologies between mammalian and insect immune defense pathways |
| PMC2645295__F1 | Airway Smooth Muscle Cell as an Inflammatory Cell |
| PMC2645305__F3 | Airway Smooth Muscle Growth in Asthma |
| PMC2645306__F2 | Migration of Airway Smooth Muscle Cells |
| PMC2645343__F2a | Drug development against metastasis-related genes and their pathways: A rationale for cancer therapy |
| PMC2645538__F5 | Possible neuroprotective mechanisms of mild mitochondrial uncoupling and caloric restriction in neurodegenerative diseases |
| PMC2645860__F2 | Pathogenetic mechanisms of CCAAT enhancer binding protein alpha (C/EBPA) dysfunction |
| PMC2645904__F3 | Schematic representations of potential signaling pathways involved in serum-deprived retinal ganglion cell-5 cells |
| PMC2645908__F5 | Model showing RBR3 role in the RBR/E2F pathway controlling the expression of MCM2-7 genes, DNA replication, and cell transformation |
| PMC2646065__F8 | Proposed model involving GSK-3 inhibition and the mTOR pathway to stimulate human Beta-cell growth and proliferation |
| PMC2646147__F6 | A model for three pathways of TLS in mammalian cells |
| PMC2646278__F5 | Pathways of global genome nuclear excision repair (GG-NER) and transcription-coupled nuclear excision repair (TC-NER) |
| PMC2647163__F3 | Advances on the Understanding of the Origins of Synaptic Pathology in AD. |
| PMC2647539__F5 | FasL proteolytic processing |
| PMC2647614__F2 | Novel Insights into Lung Transplant Rejection by Microarray Analysis |
| PMC2647628__F1 | CATERPILLER (NLR) Family Members as Positive and Negative Regulators of Inflammatory Responses |
| PMC2647704__F5 | Schematic of selenoprotein synthesis |
| PMC2647780__F1 | Signaling Logic of Activity-Triggered Dendritic Protein Synthesis |
| PMC2647860__F7 | p53, Cyclin-dependent Kinase and Abnormal Amplification of Centrosomes |
| PMC2648232__F6 | Pathway mapping of OPC differentiation inducer genes |
| PMC2648516__F1 | SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification |
| PMC2648546__F8 | A new feedback loop for p53 pathway |
| PMC2648620__F2 | Insights into the Roles of Gut Microbes in Obesity. |
| PMC2649086__F7 | KLF14-mediated TGFBRII silencing |
| PMC2649208__F2 | Molecular interaction map displaying the functional interaction of genes in the MEK/ERK output profile with established roles in ERK signaling |
| PMC2649265__F8 | Insulin-PI3K-Akt signaling in AD |
| PMC2649302__F2 | Wnt/-catenin signaling pathway |
| PMC2649302__F3 | Conversations between Wnt/Beta-catenin and MAPK signaling pathways |
| PMC2649571__F7 | Beta-Catenin-Dependent Wnt Pathway Mediates Anteroposterior Axon Guidance in Motor Neurons |
| PMC2649725__F7 | Model showing the activation of the JNK pathway upon challenge by UVB |
| PMC2649808__F5 | Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions |
| PMC2649968__F4 | Participation of DNA repair in the response to 5-fluorouracil |
| PMC2650010__F1 | Akt-dependent and independent mechanisms of mTOR regulation in cancer |
| PMC2650010__F2 | Akt-dependent and independent mechanisms of mTOR regulation in cancer |
| PMC2650010__F3 | Akt-dependent and independent mechanisms of mTOR regulation in cancer |
| PMC2650409__F6 | c-Src Regulates Akt Signaling in Response to Ghrelin via Beta-Arrestin Signaling-Independent and -Dependent Mechanisms |
| PMC2650609__F6 | Top network of upregulated genes in quadriceps muscles of COPD patients, compared with control subjects |
| PMC2651172__F7 | Possible site for alcohol-induced inhibition of muscle protein synthesis |
| PMC2651433__F2 | A nuclear SIRT1 mechanism for delaying NAD-ATP depletion through inhibition of PARP-1 is presented |
| PMC2651433__F4 | The Importance of NAD in Multiple Sclerosis. |
| PMC2651582__F1 | Metabolic reprogramming in tumor cells |
| PMC2651818__F3 | Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network |
| PMC2652039__F8 | Tumor Necrosis Factor-like Weak Inducer of Apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta activated kinase 1 |
| PMC2652310__F1 | Anaerobic metabolic pathways in C |
| PMC2652397__F1 | Dual Roles of Nrf2 in Cancer |
| PMC2652403__F1 | Signalling through the phosphatidylinositol 3-kinase (PI3K) affects cell growth, apoptosis and cell cycle regulation |
| PMC2652645__F1a | Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning |
| PMC2652867__F1 | PML regulon model is used to explain the effects of the PML protein and PML nuclear bodies on survival signaling as described in the text |
| PMC2653092__F5 | Basic Helix-Loop-Helix Factor Hand2 Regulates Autonomic Nervous System Development |
| PMC2653380__F3 | Schematic representation of bile acid synthesis by the classical neutral pathway |
| PMC2653622__F2 | PRIMARY CILIUM: AT THE CROSSROADS OF MAMMALIAN HEDGEHOG SIGNALING |
| PMC2654353__F5 | From nutrients to HIF and from HIF to metabolism |
| PMC2654353__F7 | From the extracellular matrix to HIF and from HIF to the extracellular matrix |
| PMC2654411__F3 | Time-course Comparison of Xenobiotic Activators of CAR and PPARα in Liver |
| PMC2654411__F6 | Time-course Comparison of Xenobiotic Activators of CAR and PPARA in Mouse Liver |
| PMC2654418__F6 | Crosstalk between the Androgen Receptor and Beta-Catenin in Castrate Resistant Prostate Cancer |
| PMC2654747__F2 | Summary of enzyme-catalyzed thyronamine deiodinase reactions |
| PMC2654975__F1 | Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease |
| PMC2655244__F8 | Proposed model for the signaling pathway of Cao-induced keratinocyte differentiation |
| PMC2655360__F7 | Pathway maps generated using GenMapp depicting increased glycolytic protein expression in differentiated intestinal epithelial cells relative to crypt cells |
| PMC2655379__F8 | Potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle |
| PMC2655678__F1 | ATM activation in response to DNA DSBs |
| PMC2655983__F3 | Simplified version of colorectal-cancer biological pathway in KEGG database for genes with mutation data in COSMIC |
| PMC2656226__F6 | Mitochondrial regulation of the apoptotic pathway is altered in disease and modulated by sirolimus treatment |
| PMC2656226__F9 | Complement pathway altered in disease |
| PMC2656900__F1 | Working model for Eph receptor function in tumor promotion and tumor suppression |
| PMC2657106__F1 | Activation of the G2/M checkpoint after DNA damage |
| PMC2657110__F2 | HIV-1 modulates the interferon-induced antiviral host mechanisms, protein kinase R and 2',5'-oligoadenylate synthesis |
| PMC2657476__F1 | ErbB Receptors in the Biology and Pathology of the Aerodigestive Tract |
| PMC2657775__F6 | Enrichment of Wnt signaling pathway |
| PMC2657775__F7 | Enrichment of TGF-beta signaling pathway |
| PMC2657775__F9 | Enrichment of Jak-STAT signaling pathway |
| PMC2657945__F1 | The TSC-mTOR signaling |
| PMC2657945__F2 | Regulation of the mTORC1 pathway by two distinct small GTPases |
| PMC2658537__F1 | Sample signalling scheme showing pathways known to be active in melanoma |
| PMC2658594__F4 | AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration |
| PMC2658783__F2 | The erbB family and the IGF/IGF-1R system |
| PMC2659375__F2 | MET as a target for treatment of chest tumours |
| PMC2659383__F3 | SHH signaling pathway components that have been employed in the production of genetically engineered mouse models |
| PMC2659402__F3 | Interleukin-31 acts through three signaling pathways: Jak/STAT pathway, PI3K/AKT pathway and MAPK pathway |
| PMC2659592__F7 | Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor A2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells |
| PMC2660327__F2 | Network analysis using Ingenuity pathway analysis (IPA) software |
| PMC2660380__F3 | Lysophosphatidic Acid Signaling in Airway Epithelium: Role in Airway Inflammation and Remodeling |
| PMC2660752__F6 | Metabolic origin of glyoxylate in M |
| PMC2660918__F2 | Hypothetical model for the end-joining mechanisms during CSR |
| PMC2661541__F1 | Transforming growth factor-beta (TGFB) signaling pathway |
| PMC2661568__F6 | Schematic model of sequential hippocampal aging changes |
| PMC2661789__F1 | In endothelial cells, after activation, VEGFR2 is able to stimulate the AKT/mTOR signalling pathway through PI3K |
| PMC2661888__F3 | Hypergraph representation of the Boolean model for yeast glucose repression |
| PMC2661962__F1 | Where Do MAIT Cells Fit in the Family of Unconventional T Cells? |
| PMC2662295__F5 | TRAF6- and MEKK1-mediated signal for IFNB production in the RLH/IPS-1 signaling pathway |
| PMC2662368__F2 | T cell differentiation proceeds along distinct pathways following antigen presentation by DCs |
| PMC2662467__F6 | Cell proliferation and apoptosis |
| PMC2662565__F3 | Bipolar disorder: from genes to behavior pathways |
| PMC2662567__F2 | Genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders |
| PMC2662567__F3 | Genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders |
| PMC2662580__F1 | Wnt therapy for bone loss: golden goose or Trojan horse? |
| PMC2662697__F6 | Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88 Dependent and Independent Signaling and is Reciprocally Modulated by LXR Activation |
| PMC2663056__F3 | Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling. |
| PMC2663056__F4 | Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling |
| PMC2663399__F2 | DNA Damage Tolerance: When It's OK to Make Mistakes |
| PMC2663399__F5 | DNA Damage Tolerance: When It's OK to Make Mistakes |
| PMC2663408__F15 | The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification |
| PMC2663527__F1 | The formation of leukotrienes (LTs) through the 5-lipoxygenase pathway of arachidonic acid metabolism, and the effects of LT inhibitors in different contexts |
| PMC2663816__F1 | Single-Cell Profiling Reveals the Origin of Phenotypic Variability in Adipogenesis |
| PMC2663984__F5 | Expanded canonical Wnt/GSK3 signaling pathway |
| PMC2664743__F4 | Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity |
| PMC2664745__F1 | Molecular and cellular biology of enhanced cognition |
| PMC2665046__F3 | Multivalency-Assisted Control of Intracellular Signaling Pathways: Application for Ubiquitin-Dependent N-End Rule Pathway |
| PMC2665727__F5 | Ty retrotransposition cycle |
| PMC2665757__F6 | EXT/HSPG pathway involved in both peripheral and central chondrosarcomas |
| PMC2665873__F1 | Fatty acid synthesis pathways in C |
| PMC2666018__F12 | Differential Requirement for MEK/ERK and SMAD Signaling in PAI-1 and CTGF Expression in Response to Microtubule Disruption |
| PMC2666381__F1 | TLR signaling and the role of epithelium in corneal innate defense |
| PMC2666387__F7 | Proposed Src involvement in HCEC wound healing |
| PMC2666388__F1 | DHA, NPD1, and BAPP-derived AB peptide signaling circuits in homeostatic aging and in AD |
| PMC2666391__F2 | Toll-Like Receptors and Corneal Innate Immunity |
| PMC2666503__F1 | F igure 1.– |
| PMC2666541__F1 | (panel A) ODC expression is regulated by a number of signaling pathways |
| PMC2666548__F1 | Reactions and proteins of the mitochondrial FAS pathway |
| PMC2666844__F3 | In the absence of Wnt stimulation, the APC (adenomatous polyposis coli) forms a trimeric complex, known as the "destruction complex," with glycogen synthase kinase-3B (GSK) and Axin |
| PMC2666844__F5 | Simplified schematic of hepatocyte growth factor (HGF)/MET signaling pathway |
| PMC2666844__F6 | Simplified schematic diagram of transforming growth factor-alpha/epidermal growth factor receptor signaling pathway (TGFA/EGFR) |
| PMC2667382__F8 | Phosphorylation of the Translation Initiation Factor eIF2A Increases BACE1 Levels and Promotes Amyloidogenesis |
| PMC2667705__F7 | Regulation of hepatic HNF4A expression by insulin: involvement of SREBPs and proposed liver impairments |
| PMC2667750__F8 | Proposed pathway for polyoxin biosynthesis |
| PMC2667769__F5 | Defective respiration of Δisc1 in the post-diauxic phase |
| PMC2667788__F3 | Paracrine mechanisms in adult stem cell signaling and therapy |
| PMC266780__F7 | Scheme to illustrate the separate functions and regulation of conventional nonsarcomeric myosin IIA and myosin IIB |
| PMC2667897__F1 | TGFB superfamily signaling: notes from the desert |
| PMC2667932__F1 | Model for TGFB1-induced PAI-1 expression |
| PMC2667944__F1 | Angiotensin converting enzyme 2 in the brain |
| PMC2667983__F4 | Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern Asia. |
| PMC2668232__F5 | Principles in TLR signaling |
| PMC2668236__F2 | Major pathway and inflammatory mediators of sepsis and its related conditions |
| PMC2668371__F9 | The proposed model |
| PMC2668926__F1 | EGFR Signaling Pathway |
| PMC2668954__F4 | Mechanotransduction gone awry |
| PMC2668982__F2 | CCN1 signaling and crosstalk with TNFA |
| PMC2669301__F1 | Tyrosine kinase network regulating mast cell activation |
| PMC2669548__F1 | Generalized schematic presentation of signaling pathways targeted by molecular therapies in malignant glioma |
| PMC2670002__F7 | Pathway in colorectal cancer (CRC) progression from normal colon to late-stage cancer |
| PMC2670022__F1 | Pharmacological targeting of the serotonergic system for the treatment of obesity |
| PMC2670105__F1 | IMP impedes Ras mitogenic signaling by limiting KSR1 complexes |
| PMC2670521__F9 | New Microbicidal Functions of Tracheal Glands: Defective Anti-Infectious Response to Pseudomonas aeruginosa in Cystic Fibrosis |
| PMC2670612__F2 | Tumor resistance to EGFR-targeted therapies |
| PMC2670830__F4 | Signaling in pterygium |
| PMC2670967__F2 | Schematic (simplified) representation of enzymatic and metabolite components of the liver methionine metabolic pathway, and the influence of ethanol consumption |
| PMC2670969__F4 | PBT-1 induced genes in different pathways according to the KEGG and BIOCARTA pathway databases |
| PMC2671025__F6 | Role of adiponectin in human skeletal muscle bioenergetics |
| PMC2671376__F7 | Signaling in the PI3K/Akt pathway and deregulations detected in GRMD skeletal muscle |
| PMC2671566__F7 | Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor |
| PMC2671631__F1 | The L-arginine biosynthetic pathway and its association to proline and polyamine biosynthesis |
| PMC2671642__F5 | Comprehensive genomic characterization defines human glioblastoma genes and core pathways |
| PMC2671717__F7 | Schematic Overview of Pyrimidine de Novo Synthesis, Salvage, and Degradation.Nucleotides synthesized de novo enter the nucleotide pool and become further converted to nucleic acids and other metabolic intermediates |
| PMC2671802__F1 | ALPS and CEDS illustrate signaling pathways for lymphocyte apoptosis and activation |
| PMC2671916__F6 | Novel functional modules with dynamic gene expression changes potentially linked to prion pathophysiology: (A) androgen metabolism, (B) iron metabolism, (C) arachidonate/phospholipid metabolism |
| PMC2671988__F2 | Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder. |
| PMC2672206__F7 | Regulation of osteogenic differentiation of MC3T3-E1 cells by substrate rigidity |
| PMC2672430__F2 | Prodeath or Prosurvival: Two Facets of Hypoxia Inducible Factor-1 in Perinatal Brain Injury |
| PMC2672887__F1 | Model for the regulation of type 1 interferon signalling by filamin B |
| PMC2672935__F2 | Regulated molecules in canonical signalling pathways identified by IPA |
| PMC2673236__F1 | Schematic illustration of one-carbon metabolism pathway |
| PMC2673242__F1 | Loss of PTEN function results in accumulation of PIP3, which activates a cascade of signaling molecules |
| PMC2673277__F7 | The assembly of 14-3-3:Shc scaffolds |
| PMC2673422__F6 | Hypoxia-invoked response of the glycolysis gene network |
| PMC2673547__F8 | Oncogenic Function of ATDC in Pancreatic Cancer Through Wnt Pathway Activation and Beta-catenin Stabilization |
| PMC2673908__F2 | Unifying model of Wnt signaling with regard to cardiomyogenesis |
| PMC2673912__F6 | Activin Modulates the Transcriptional Response of LBT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation |
| PMC2673912__F8 | Activin Modulates the Transcriptional Response of LBT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation |
| PMC2673958__F1 | Role of Adenomatous Polyposis Coli (APC) and Microtubules in Directional Cell Migration and Neuronal Polarization |
| PMC2674015__F2a | Toll-like Receptors: Novel Pharmacological Targets for the Treatment of Neurological Diseases |
| PMC2674123__F10 | Signaling cascade of PI3K/AKT pathway |
| PMC2674225__F2 | Repression of TGFB-RII and abrogated signaling through the Smad pathway |
| PMC2674579__F1 | GST-MDA-7 causes PERK-dependent vacuolization and JNK pathway activation in transformed cells that leads to cell death |
| PMC2674698__F1 | Structures and metabolic pathway of gangliosides () |
| PMC2674702__F1 | Metabolism of extracellular and intracellular bioactive lipids |
| PMC2674738__F1 | Circulating blood monocytes adhere to activated endothelium at sites of disease or injury |
| PMC2674743__F2 | Altered insulin signaling by lipid intermediates |
| PMC2674747__F1 | Illustration of differences in the expression of genes for early steps of sphingolipid metabolism using a KEGG-based microarray analysis tool (GenMapp v2.1) that has been modified to display this pathway more completely (www.sphingomap.org) |
| PMC2674807__F2 | Common polymorphisms in the genes associated with Alzheimer's Disease (AD) |
| PMC2675004__F1 | Crosstalk via the NFKB Signaling System |
| PMC2675030__F3 | Steps in the generation of Th17 cells |
| PMC2675492__F1 | Biochemical schematics: This figure maybe regarded as the biochemical underpinning of our model |
| PMC2675552__F3 | Mechanism of action of toll-like receptors (TLRs) |
| PMC2675653__F1 | CART analysis of NER pathway and esophageal cancer risk |
| PMC2675709__F5 | Comparison of metabolites and transcripts in glycolysis, tricarboxylic acid (TCA) cycle, and pH-regulating pathways between the wild type (WT) and the stop1 mutant |
| PMC2675865__F7 | Bile acids and FGF19 increase stability of hepatic SHP by inhibiting ubiquitin–proteasomal degradation and activating ERK pathway |
| PMC2675987__F1 | Calmodulin-dependent nuclear import and disease |
| PMC2676108__F3 | INHIBITOR OF APOPTOSIS (IAP) PROTEINS IN EUKARYOTIC EVOLUTION AND DEVELOPMENT: A MODEL OF THEMATIC CONSERVATION |
| PMC2676302__F5 | Major trends in mRNA expression at 56 days on experimental diets and summary network analysis among genes |
| PMC2676316__F2 | Isoprenoid Metabolism and the Pleiotropic Effects of Statins |
| PMC2676446__F1 | Regulation of p53 and MDM2 and the outcomes of p53 activation |
| PMC2676714__F4 | Pathways analysis on the set of genes contained in the SNP component |
| PMC2676730__F5 | The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies |
| PMC2676892__F3 | Chronic Lymphocytic Leukemia and B and T Cells Differ in Their Response to Cyclic Nucleotide Phosphodiesterase Inhibitors |
| PMC2676994__F1 | Schematic model illustrating multiple signaling pathways in regulating StAR gene transcription |
| PMC2677061__F1 | Postnatal Roles of GDNF Family Members in Nociceptors Plasticity. |
| PMC2677203__F7 | Signaling via the TgfB type I receptor Alk5 in heart development |
| PMC2677387__F1 | mTORC1 activation by nutrients and growth factors |
| PMC2677399__F2 | Nuclear Factor KB, Airway Epithelium, and Asthma |
| PMC2677410__F2 | Novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell |
| PMC2677440__F7 | Rhinovirus-Induced Major Airway Mucin Production Involves a Novel TLR3-EGFR-Dependent Pathway |
| PMC2677552__F3 | PharmGKB pathway diagrams |
| PMC2677752__F1 | Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development |
| PMC2677763__F7a | Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways |
| PMC2678071__F1 | Graphical representation of the gp130/JAK/STAT pathway |
| PMC2678157__F9 | The steroid synthesis pathway showing genes regulated in this study |
| PMC2678244__F1 | Abl Tyrosine Kinases in T-cell signaling |
| PMC2678599__F7 | Filia's role in ensuring euploidy of early cleavage embryos |
| PMC2678718__F1 | Conversion of subendothelial macrophages into cholesterol-laden foam cells is believed to constitute the foundation of the atherosclerotic lesion |
| PMC2678983__F4 | IFN-gamma signaling pathway |
| PMC2679052__F7 | Diagram summarizing differences in expression of interaction genes enriched within the KEGG p53 signaling pathway, and possible interactions of corresponding proteins with the androgen receptor |
| PMC2679127__F2 | PRRs and their corresponding ligands |
| PMC2679155__F1 | Integrin-RTK signaling |
| PMC2679172__F1 | Crosstalk at the initial encounter: Interplay between host defense and ameba survival strategies |
| PMC2679302__F2 | Network contains downregulated genes and identified around NFKB gene |
| PMC2679364__F6 | OVARIAN CANCER |
| PMC2679427__F1 | Regulation of rat GSTA2 and NQO1 gene expression |
| PMC2679427__F3 | Proposed Nrf2-ARE signaling pathway |
| PMC2679749__F3 | Control of autophagy |
| PMC2679751__F7 | Proposed model for functional interaction between Ncs-1a, Pi4kB, and Arf1 in trafficking and secretion |
| PMC2679770__F3 | Proposed saxitoxin biosynthetic pathway |
| PMC2679904__F1 | TLR mediated signaling |
| PMC2679989__F1 | Function of Nod-like Receptors in Microbial Recognition and Host Defense |
| PMC2680003__F1 | Proposed pathway for the NDP-sugar donor substrate of glycosyltransferase GilGT |
| PMC2680180__F1 | Mitochondria–A Nexus for Aging, Calorie Restriction, and Sirtuins? |
| PMC2680287__F1 | Unraveling the complexities of the interferon response during SARS-CoV infection |
| PMC2680291__F1 | Illustration of some of the key enzymes involved in the metabolism of methotrexate (MTX) |
| PMC2680466__F3 | Pathway representation of relative expression levels by tissue |
| PMC2680597__F1 | Methylobacterium Genome Sequences: A Reference Blueprint to Investigate Microbial Metabolism of C1 Compounds from Natural and Industrial Sources |
| PMC2680672__F2 | Regulation mechanisms for Itch-mediated Th2 differentiation.TCR triggering plus CD28-mediated costimulation results in the activation of MEKK1-JNK signaling pathway, which induces the serine/threonine phosphorylation of Itch |
| PMC2681001__F1 | Biosynthetic Pathway of Coenzyme Q10 |
| PMC2681266__F1 | NFKB activation in cancer |
| PMC2681728__F8 | Proposed model of the role of p47 in E |
| PMC2682019__F9 | A link between glucose and insulin signaling in Beta-cells |
| PMC2682028__F9 | Changes in metabolism in Prx1-Cre; PORlox/lox limb bud cells and levels of cholesterol |
| PMC2682038__F8 | An integrated model for the function of TopBP1 in the normal cell cycle and in cancer cells |
| PMC2682371__F2 | ErbB proteins are type I transmembrane receptor tyrosine kinases |
| PMC2682514__F1 | Nodes with the highest relative betweenness centrality (in orange) and their interacting partners (blue) in the pancreatic cancer pathway |
| PMC2682636__F4 | The comorbidity of HIV-associated neurocognitive disorders and Alzheimer's disease: a foreseeable medical challenge in post-HAART era |
| PMC2683106__F5 | Promoting cell proliferation and repressing differentiation |
| PMC2683291__F4 | Mammalian target of rapamycin (mTOR) signalling cascade |
| PMC2683382__F2 | Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites |
| PMC2683584__F1 | Control of Cell Number in the Sexually Dimorphic Brain and Spinal Cord |
| PMC2683622__F9 | Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway |
| PMC2683667__F4 | Induction of IFN-signaling pathways in HCV-infected uPA-SCID mice (A) and patients (B) |
| PMC2683723__F6 | Insulin-EGF signal integration |
| PMC2683871__F6 | p53-regulated pathway analysis using the Ingenuity Pathway Knowledge Base (IPKB) |
| PMC2684021__F1 | The fungal cell wall and downstream cellular responses following engagement of Dectin-1 and TLRs on antigen presenting cells (APC) |
| PMC2684140__F9 | Schematic representation of the S |
| PMC2684375__F1 | Factors involved in the regulation of corporal smooth muscle tone |
| PMC2684527__F2 | Stochasticity in Protein Levels Drives Colinearity of Gene Order in Metabolic Operons of Escherichia coli |
| PMC2684550__F2 | In MSTN-null mice, regulators of the PI3K pathway and cell survival/apoptosis likely contribute to muscle hypertrophy |
| PMC2684656__F1 | Diagrammatic representation of the signalling pathways activated in the unfolded protein response following ER stress |
| PMC2684849__F3 | Transcriptional regulation of human small nuclear RNA genes |
| PMC2684867__F1 | VHL Loss of Function and Its Impact on Oncogenic Signaling Networks in Clear Cell Renal Cell Carcinoma |
| PMC2684977__F2 | Biologic actions of isoprenoids |
| PMC2685460__F7 | Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae |
| PMC2685579__F1 | Synthetic pathways for polar lipids |
| PMC2685661__F10 | NO/cGMP and calcium signaling in osteoblast mechanotransduction |
| PMC2685877__F1 | Combined Yeast-derived Beta-Glucan with Anti-tumor Monoclonal Antibody for Cancer Immunotherapy. |
| PMC2685917__F9 | Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells |
| PMC2685981__F1 | Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis |
| PMC2685981__F3 | Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis |
| PMC2686112__F1 | VHL gene complex targets hypoxia-inducible factors (HIF) for ubiquitin-mediated degradation |
| PMC2686461__F1 | BCR signaling pathway |
| PMC2686679__F12 | Signaling pathway leading to Egr-1 biosynthesis in thrombin or carbachol-stimulated 39M1-81 cells |
| PMC2686735__F5 | Map of BCR-pathway |
| PMC2687355__F7 | The signaling pathway MyD88 ‡’ p38 ‡’ EGR-1/AP-1 is essential for GBS-induced transcriptional activation of TNF |
| PMC2688381__F4 | Azithromycin Treatment Alters Gene Expression in Inflammatory, Lipid Metabolism, and Cell Cycle Pathways in Well-Differentiated Human Airway Epithelia |
| PMC2688528__F7 | Model of stress -signalling to PRC1: In the nucleus of resting cells, a sub-population of MK2 (and MK3) is associated to PRC1 via specific interaction to Edr2 (and/or Edr1) |
| PMC2688657__F1 | Antigrowth signaling pathway and cluster around SMAD proteins |
| PMC2688657__F3 | Apoptosis pathway |
| PMC2688657__F5 | Growth signal pathway |
| PMC2688747__F4 | Fgf and Sdf-1 Pathways Interact during Zebrafish Fin Regeneration |
| PMC2688755__F2 | Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen |
| PMC2688935__F3 | Networks used to generate simulated data |
| PMC2689134__F4 | Pathogenesis of holoprosencephaly |
| PMC2689231__F6 | Purine biosynthetic pathway, showing protein abundance changes for the P |
| PMC2689776__F7 | Proteomics and Pathway Analysis Identifies JNK Signaling as Critical for High Linear Energy Transfer Radiation-induced Apoptosis in Non-small Lung Cancer Cells |
| PMC2689781__F7 | Grade-dependent Proteomics Characterization of Kidney Cancer |
| PMC2690004__F3 | Metabolic reconstruction of H |
| PMC2690394__F2 | Molecular targets of natural chemopreventive agents |
| PMC2690586__F1 | Maintenance of the G1/S DNA damage checkpoint in the presence and absence of Cdk2 |
| PMC2690992__F2 | Signaling control of mesenchymal and amoeboid cell phenotypes |
| PMC2691147__F1 | Hh signalling–a simplified model |
| PMC2691592__F7 | Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-Induced Apoptosis |
| PMC2691779__F1 | Schematic overview of the human tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) apoptosis pathway |
| PMC2691965__F2 | Toll-like receptor (TLR) activation |
| PMC2692221__F1 | BER subpathways for damaged bases and DNA strand breaks |
| PMC2692251__F2 | HuR and/or AUF1 differentially regulate mRNAs encoding cell cycle and Erk1/Erk2 Mapk signaling-related genes in MCT-1-transformed cells |
| PMC2692400__F1 | Hormone and nutrient signaling pathways modulating leptin translation |
| PMC2692402__F1 | Glycerol phosphate pathway for de novo triacylglycerol (TAG) and glycerophospholipid synthesis |
| PMC2692422__F7 | IL-1Beta-induced upregulation of RGS4 expression in colonic SMCs via canonical IKK2/IKBA/NFKB signaling is differentially modulated by the MAPK and PI3K/Akt/GSK3B pathways |
| PMC2692634__F1 | THE ENZYMES OF THE 10-FORMYL-TETRAHYDROFOLATE SYNTHETIC PATHWAY ARE FOUND EXCLUSIVELY IN THE CYTOSOL OF THE TRYPANOSOMATID PARASITE LEISHMANIA MAJOR |
| PMC2692823__F2 | Hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem |
| PMC2693146__F8 | Model depicting the dual role of cGKI in BMP signalling pathway cGKI regulates BMP signalling through (light blue) modulation of BMP receptors at the cell surface and enhancement of R-Smad phosphorylation and thus Smad activation |
| PMC2693232__F2 | Unifying model of TGFB signaling in breast epithelium |
| PMC2693384__F2 | Regulation of Vascular Permeability by Sphingosine 1-Phosphate |
| PMC2693450__F3 | Lipodystrophies: Disorders of adipose tissue biology |
| PMC2694412__F6 | Somatic mutations affect key pathways in lung adenocarcinoma |
| PMC2694443__F8 | BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway |
| PMC2694487__F5 | Human presenilin 1 and 2 (PSEN1 and PSEN2) subnetworks |
| PMC2694555__F3 | Response to pathway inhibitors of tumor cells depends on the mechanism of pathway activation |
| PMC2694580__F2 | Biological actions of isoprenoids |
| PMC2694616__F1 | Genomic Strategy to Elucidate Modules of Oncogenic Pathway Signaling Networks |
| PMC2694804__F2 | Summary of the pathways transduced by the primary cilium |
| PMC2694829__F6 | HIV-1 TAT T cell receptor signaling pathway |
| PMC2694962__F1 | Schematic illustration of overview of one-carbon metabolism pathway, linking to methylation reactions and nucleotide synthesis |
| PMC2695202__F2 | Emerging anti-inflammatory therapy |
| PMC26952__F7 | Activation of specific target genes by TGFB and Wnt pathways |
| PMC2695499__F10 | Changes in OSM signaling |
| PMC2695762__F2 | Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity |
| PMC2695822__F10 | Display of genes with high expression in CT embryos |
| PMC2695822__F9 | Display of genes with high expression in IVF embryos |
| PMC2695826__F1 | Ingenuity pathway analysis identified a network of genes down regulated in response to 60 minutes of ischemia in aged mouse liver |
| PMC2695826__F2 | Age-Related Decrease in Proteasome Expression Contributes to Defective NFKB Activation during Hepatic Ischemia/Reperfusion |
| PMC2695927__F4 | Bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease |
| PMC2696125__F2 | Docosanoids are multifunctional regulators of neural cell integrity and fate: significance in aging and disease |
| PMC2696130__F3 | Liquid Movement Across the Surface Epithelium of Large Airways |
| PMC2696130__F4 | Liquid Movement Across the Surface Epithelium of Large Airways |
| PMC2696288__F7 | Protein Acetylation Microarray Reveals NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis |
| PMC2696318__F1 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F3 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F4 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F5 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F6 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696318__F7 | ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE |
| PMC2696319__F1 | Sites of mutation which can result in activation of the Raf>MEK>ERK pathway |
| PMC2696328__F5 | Proposed model for the effect of HPTE in the granulosa cell |
| PMC2696359__F1 | TNF-Induced MAP Kinase Activation Oscillates in Time |
| PMC2696553__F1 | Store-operated Ca2+ entry in T cells |
| PMC2696566__F1 | Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy |
| PMC2696566__F2 | Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy |
| PMC2696814__F1 | Autophagy in the Pathogenesis of Disease |
| PMC2697061__F2 | Endoplasmic reticulum stress in disorders of myelinating cells |
| PMC2697172__F8 | Sub-network associated with the Wnt signaling pathway |
| PMC2697290__F1 | Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart |
| PMC2697617__F1 | Live Longer Sans the AT1A Receptor |
| PMC2697619__F5 | Proposed signaling pathways by which the Tec kinases regulate JNK activation, actin polymerization, and cytokine expression in LPS-stimulated neutrophils |
| PMC2697682__F1 | Interaction of AEA with CB and TRPV1 receptors and its metabolism by FAAH and COX-2 |
| PMC2697824__F3 | Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: A review |
| PMC2698215__F4 | Salivary and Intestinal Complement System Inhibitors in the Midgut Protection of Triatomines and Mosquitoes |
| PMC2698322__F3 | Complex relationship between PI3-K, mTOR and PKB signalling |
| PMC2698322__F4 | Key proteins regulated by PKB that are involved in metabolism (yellow); cell cycle progression (green); cellular growth (red); cell survival and apoptosis (blue); angiogenesis (orange) and neurological processes (purple) |
| PMC26984__F1 | Proposed pathway of EGF-induced cell proliferation of ER- breast cancer cells |
| PMC2698574__F9 | The VACV- and CPXV-stimulated PI3K/Akt pathway of biological relevance in spontaneously immortalized A31 and MEF cells |
| PMC2698645__F1 | Simplified schematic representation of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway driven by muscle contraction, insulin, essential amino acids (leucine), and/or energy |
| PMC2698645__F2 | Simplified schematic representation of the interaction between the mTORC1 and ERK1/2 signaling pathways following muscle contraction and/or insulin stimulation |
| PMC2698768__F9 | Model of CD28 signaling pathways initiated by the distal and proximal motifs |
| PMC2698936__F2 | Integrins in Lens Development and Disease |
| PMC2699281__F2 | Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease |
| PMC2699281__F3 | Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease |
| PMC2699361__F1 | The ER-mitochondria apoptotic signalling pathway operating in cells devoid of mitochondrial BAK and BAX, and of ER-located BAX |
| PMC2699768__F1 | Aryl hydrocarbon receptor (AhR) pathway as a regulatory pathway for cell adhesion and matrix metabolism |
| PMC2699768__F3 | Aryl hydrocarbon receptor (AhR) pathway as a regulatory pathway for cell adhesion and matrix metabolism |
| PMC2699853__F1 | Diabetes alters the expression of multiple genes of the TGFB pathway (left side of the panel) and BMPs pathway (right side) in rat retinal vessels |
| PMC2699904__F7 | Inter-relationships of genes associated with apoptosis differentially expressed in the lacrimal glands of C57BL/6.NOD-Aec1Aec2 mice |
| PMC2699904__F8 | Schematic showing inter-relationships of clustered genes associated with fatty acid, lipid and lipoprotein homeostasis based on differentially-expressed genes identified in lacrimal glands of C57BL/6.NOD-Aec1Aec2 mice |
| PMC2699967__F2 | Signaling pathways initiated by TLR-2 and TLR-4 activation |
| PMC270001__F2 | Chemoresistance in Human Ovarian Cancer Cells |
| PMC2700035__F6 | Load-driven signaling pathways predicted with ankle loading at 1 h after the last loading |
| PMC2700095__F10 | Alternative kinetic model incorporating unknown transcription factor (TFx) activation by Eda/Edar signaling |
| PMC2700213__F1 | Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians |
| PMC2700405__F1 | The canonical Wnt/Beta-catenin signaling pathway |
| PMC2700428__F2 | Some cellular processes implicated in the pathogenesis of PAH |
| PMC2701191__F4 | Regulation of cell junction dynamics by cytokines in the testis - a molecular and biochemical perspective |
| PMC2701885__F2 | Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence |
| PMC2702150__F3 | FIBROTIC DISEASE AND THE TH1/TH2 PARADIGM |
| PMC2702319__F4 | Distributions of the orthologous gene groups containing duplicate genes that arose through 3R-WGD (shown as gray boxes) in the network diagrams |
| PMC2702500__F1 | Metabolic reconstruction of Db |
| PMC2702690__F9 | Molecular Mechanisms of HIF-1A Modulation Induced by Oxygen Tension and BMP2 in Glioblastoma Derived Cells |
| PMC2702844__F2 | Cell biology of autophagy in metazoans: a developing story |
| PMC2703803__F1 | The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target |
| PMC2703816__F3 | Identification of neuronal target genes for CCAAT/Enhancer Binding Proteins. |
| PMC2704234__F3 | Immune activation induced by Beta-glucans |
| PMC2704241__F5 | Hepatic methionine metabolism and GSH synthesis |
| PMC2704251__F1 | Porphyromonas gingivalis-Host Interactions: Open War or Intelligent Guerilla Tactics? |
| PMC2704458__F2 | Histone Acetylation in Drug Addiction |
| PMC2704469__F8 | Scheme indicating expression of Tcf4 proteins and effects of Wnt-Beta-catenin signaling to inhibit the transition from premyelinating to mature oligodendrocyte |
| PMC2704571__F2 | Diagrammatic representation of hormone therapy-induced changes in gene expression in the dorsal raphe block |
| PMC2704572__F1 | Complement effectors generated during activation contribute to various mechanisms that limit tumor growth |
| PMC2704572__F2 | Some complement proteins can accelerate tumor growth |
| PMC2704819__F2 | Catabolic pathways encoded by the T |
| PMC2704867__F5 | Darpp-32 and Its Truncated Variant t-Darpp Have Antagonistic Effects on Breast Cancer Cell Growth and Herceptin Resistance |
| PMC2705117__F3 | Role of peroxisome-proliferator-activated receptor B/D (PPARB/D) in gastrointestinal tract function and disease |
| PMC2705893__F1 | Protein kinase Cι: human oncogene, prognostic marker and therapeutic target |
| PMC2705999__F3 | Castration-Adapted Prostate Cancer: Targeting Androgen Metabolic Pathways in Recurrent Disease |
| PMC2706143__F2 | The Endoplasmic Reticulum and the Unfolded Protein Response |
| PMC2706143__F3 | Endoplasmic Reticulum and the Unfolded Protein Response |
| PMC2706303__F2 | Bioelectric mechanisms in regeneration: unique aspects and future perspectives |
| PMC2706609__F1 | ERK1/2 pathway in airway epithelial cell responses to cigarette smoke |
| PMC2707240__F2 | Proposed model for As2O3-dependent activation of the mTOR pathway in a negative feedback regulatory manner in malignant cells |
| PMC2707261__F1 | Regulation of glycolysis, glutaminolysis and de novo nucleotide biosynthesis in tumor cells |
| PMC2707271__F5 | Proposed mechanism for MAP4K3 cell death signaling |
| PMC2707344__F4 | Metabolic implication of leaf mitochondria during water stress |
| PMC2707511__F6 | DNA Topoisomerase I Inhibitors: Chemistry, Biology and Interfacial Inhibition |
| PMC2707763__F6 | PROK1 induction of RCAN1-4 and IL-8 |
| PMC2708714__F2 | Direct targets of WT1 identified in the Wnt signaling pathway |
| PMC2708980__F8 | Proposed signaling pathway |
| PMC2709066__F1 | De novo purine synthesis pathway |
| PMC2709272__F1 | Wnt/Beta-catenin signaling in adipogenesis and metabolism |
| PMC2709380__F7 | Hypothetical model of transcriptional regulation of the p21 gene and p53 pathway |
| PMC2709429__F11 | Production of Superoxide Anions by Keratinocytes Initiates P. acnes-Induced Inflammation of the Skin |
| PMC2709717__F1 | IGF system: receptors, ligands, and signaling pathways |
| PMC2709856__F1 | It's all in the family: multiple Toll-like receptors offer promise as novel therapeutic targets for stroke neuroprotection |
| PMC2710138__F1 | Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is an antagonist of class I phosphatidylinositol 3—kinase (PI3K) signaling |
| PMC2710138__F2 | Phosphatidylinositol 3–kinase (PI3K) signaling pathway |
| PMC2710138__F4 | Mechanistic model of enhanced activation induced by the E545K mutation in p110A |
| PMC2710138__F8 | Feedback inhibition of the phosphatidylinositol 3–kinase (PI3K) pathway |
| PMC2710522__F1 | Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data |
| PMC2710681__F4 | Model describing TLS across CPD in human cells |
| PMC2711321__F2 | Wiring diagrams for a three-module decomposition of the intrinsic apoptotic pathway |
| PMC2711664__F1 | Signal transduction mechanisms implicated in leptin action |
| PMC2711774__F2 | Proposed biosynthetic pathway for the disorazoles |
| PMC2712099__F2 | The aryl hydrocarbon receptor (AHR) signalling pathway |
| PMC2712453__F2 | G1-phase signaling pathways inferred with different heuristics |
| PMC2712453__F3 | S-phase signaling pathways inferred with different heuristics |
| PMC2712453__F5 | Erb-associated signaling pathways |
| PMC2712453__F6 | TLR-mediated innate immune signaling pathway |
| PMC2712453__F7 | Signaling pathway inferred from a gene regulatory network |
| PMC2712597__F1 | Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways |
| PMC2712597__F6 | Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways |
| PMC2712626__F1 | The Double Life of Irs |
| PMC2712666__F3 | TNF superfamily: costimulation and clinical applications |
| PMC2712749__F1 | T cell receptor signalling canonical pathway obtained by IPA obtained in comparison MM8_PM8 |
| PMC2712786__F1 | Pathways of extrinsic and intrinsic apoptosis, highlighting roles of Bcl-2 family members |
| PMC2713013__F3 | MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES |
| PMC2713013__F7 | MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES |
| PMC2713123__F6 | Early- and late-phase platelet aggregation regulated through PAR1 |
| PMC2713245__F1 | Signal transduction through activin receptors |
| PMC2713319__F1 | Apoptosis and Epithelial Injury in the Lungs |
| PMC2713319__F3 | Apoptosis and Epithelial Injury in the Lungs |
| PMC2713330__F1 | Innate Immunity in the Lungs |
| PMC2713346__F1 | Crz1 enters the nucleus in short stochastic bursts lasting about 2 min after undergoing dephosphorylation in the cytoplasm by the calcium-activated phosphatase calcineurin (Cn) (, ) |
| PMC2713381__F8 | MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway |
| PMC2713566__F1 | Mitochondrial pathways of electron flow resulting from the substrates and inhibitors used in this study |
| PMC2713571__F1 | Proposed cuticle pigmentation and sclerotization metabolic pathway in T |
| PMC2713831__F5 | Local Network Topology in Human Protein Interaction Data Predicts Functional Association |
| PMC2714185__F1 | Role of ATM in cellular responses |
| PMC2714185__F3 | Major regulatory steps in the process of DNA damage response (DDR) |
| PMC2714639__F6 | MT1-MMP expression in first trimester trophoblasts is stimulated by insulin, IGF1 and IGF2 by different signalling pathways |
| PMC2714846__F6 | Estradiol-17B, prostaglandin E2 (PGE2) and the prostaglandin E2 receptor are involved in PGE2 positive feedback loop in the porcine endometrium |
| PMC2715000__F8 | Summary of caspase 2-mediated signaling cascades in heat-induced germ cell apoptosis |
| PMC2715236__F6 | Model for the role of FANCM in the DNA damage response |
| PMC2715245__F7 | Comparison of models for FRAXA and APC-inducible chromosome fragility |
| PMC2715501__F1 | Study background |
| PMC2715808__F8 | Regulation of mTORC1 signaling by mTOR S1261 phosphorylation |
| PMC2715810__F7 | Model of PERK pathway controlling rRNA transcription and translation in comparison to mTOR |
| PMC2715958__F1 | One possible pathway which regulates cell proliferation in response to strain on collagen |
| PMC2715958__F2 | One possible pathway which regulates cell migration in response to strain on fibronectin |
| PMC2715971__F2 | Interaction between insulin and interferon-alfa signaling pathway |
| PMC2716493__F1 | Two main pathways involved in apoptosis regulation |
| PMC2716541__F6 | Apoptosis of CD4+CD25high T Cells in Type 1 Diabetes May Be Partially Mediated by IL-2 Deprivation |
| PMC2716750__F1 | Gene regulatory networks in kidney development |
| PMC2716751__F2 | The concept of angiotensin II-growth factor cross-talk in ureteric bud morphogenesis |
| PMC2716793__F3 | Spatial complexity and control of a bacterial cell cycle |
| PMC2716801__F1 | Schematic illustration of the Warburg effect in tumor cells and in early asymptomatic endothelial cell dysfunction |
| PMC2717566__F7 | Proposed model of p,p′-DDE-induced signaling pathways leading to apoptosis |
| PMC2717887__F2 | Clusterin as a critical signaling node |
| PMC2718282__F8 | The role of Mal connecting PI3K to TLR2/6 |
| PMC2718437__F2a | Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor B |
| PMC2718437__F4a | Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor B |
| PMC2718491__F3 | Multiple regulatory pathways for N-WASP and WAVE2 activation |
| PMC2718502__F1 | The NADP-ME type of C4 pathway in sorghum and maize |
| PMC2718504__F5 | Predicted general metabolism and solute transport in T |
| PMC2718747__F10 | A model of EGF/EGFR-induced inhibition of a Luminal-A phenotype in MCF-7 cells |
| PMC2719108__F2 | Schematic representation of the renin angiotensin system |
| PMC2719424__F8 | DUOX1 involvement in TLR-mediated IL-8 production in response to bacterial stimuli |
| PMC2719559__F2 | Paracrine and autocrine mechanisms of Akt-mediated tumor-stromal interactions |
| PMC2719801__F2 | Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways |
| PMC2719801__F3 | Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways |
| PMC2719943__F1 | Reduced levels of neurotransmitter-degrading enzyme PRCP promote obesity |
| PMC2720031__F1 | GR signal transduction pathway |
| PMC2720036__F1 | Selective Raf Inhibition in Cancer Therapy |
| PMC2720036__F5 | Selective Raf Inhibition in Cancer Therapy. |
| PMC2720065__F8 | Proposed signaling pathway of mmLDL-induced, TLR4/Syk-dependent ROS generation and proinflammatory cytokine expression |
| PMC2720262__F1 | Summary of consequences on signal transduction and brain architecture of conditional Pten or Pdk1 deletion, alone or in combination |
| PMC2720375__F7 | Genome-Wide Screen of Genes Required for Caffeine Tolerance in Fission Yeast |
| PMC2720436__F1 | Hippo pathway, a vital growth regulator of cell proliferation and apoptosis was initially identified by mosaic screens in Drosophila melanogaster (,) |
| PMC2720607__F2 | Principal enzymes and substrates of the folate pathway involved in formation of tetrahydrofolate (THF) and its utilisation in the thymidylate cycle |
| PMC2720726__F1 | IFNB activated pathway |
| PMC2721253__F2 | Modes of neurite growth inhibition of molecules expressed on CNS myelin and oligodendrocytes |
| PMC2721285__F1 | RAS/MAP kinase signaling pathway |
| PMC2721360__F2 | Colorectal cancer cells share the WNT pathway in response to growth suppression by APHS-mediated COX-2 inhibition |
| PMC2721377__F1 | Molecular toll-like receptors (TLRs) of the human gastrointestinal (GI) tract which act as sensors and are the first responders in the major pathway by which the immune system detects infection or damaged tissue |
| PMC2721397__F2 | Key pathways in hepatocarcinogenesis and molecularly targeted agents currently under investigation in treatment of advanced HCC |
| PMC2721475__F1 | Downstream targets of IGF-1R |
| PMC2721684__F1 | Signaling pathways triggered by TLR3, TLR4 and TLR1-TLR2 |
| PMC2721689__F1 | Structural and functional modules in RNA interference |
| PMC2721821__F6 | Graphical representation of the Hh signaling pathway in its activated state and possible sites of HPI action |
| PMC2721971__F3 | EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis†|
| PMC2721971__F4 | The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis† |
| PMC2722023__F4 | Genome-Wide mRNA Expression Analysis of Hepatic Adaptation to High-Fat Diets Reveals Switch from an Inflammatory to Steatotic Transcriptional Program |
| PMC2722148__F1 | MAPK transduction signaling pathway |
| PMC2722219__F1 | The TSC/mTOR signaling pathway |
| PMC2722250__F2 | Silent chromatin assembly in budding and fission yeast |
| PMC2722335__F1 | Adipocyte lineage commitment and terminal differentiation |
| PMC2722510__F7 | Proposed pathway involved in the regulation of the osteoblast F-actin cytoskeleton, based upon previous literature and the current experimental results |
| PMC2722767__F3 | Application of SysPTM tools |
| PMC2722780__F8 | Putative BK-BKAP interactions derived from the BK interactome in mouse cochlea |
| PMC2723150__F1 | Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is central for physiological responses to extracellular and intracellular signals |
| PMC2723760__F4 | HERPUD1 Ingenuity Pathway Analysis illustrates interactions between indicated proteins |
| PMC2723786__F1 | BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells |
| PMC2723817__F1 | Targeting lung inflammation: novel therapies for the treatment of COPD |
| PMC2723867__F1 | Dynamics of Membrane Trafficking Downstream of B and T Cell Receptor Engagement: Impact on Immune Synapses |
| PMC2724002__F2 | Controlling Hair Follicle Signaling Pathways through Polyubiquitination |
| PMC2724029__F4 | Signaling networks upregulated in migrating neuroblasts |
| PMC2724029__F5 | Signaling networks upregulated in migrating neuroblasts |
| PMC2724047__F5 | Major cell signaling pathways activated by bile acids in hepatocytes |
| PMC2724047__F6 | Activation of the Akt (insulin signaling pathway) and FXR by bile acids in hepatocytes |
| PMC2724105__F2 | The postreceptor insulin signaling pathway and insulin-independent 5'-adenosine monophosphate kinase (AMPK) beginning from insulin binding to its receptor to GLUT4 translocation via vesicular trafficking |
| PMC2724271__F4 | Metabolic map of HIF-target genes |
| PMC2724309__F2 | Steroidogenesis pathway: Steroids are in bold; enzymes and cholesterol transport proteins are in italics |
| PMC2724396__F1 | Modified Lee-Heinrich model of wnt pathway |
| PMC2724661__F1 | Complement system in AD |
| PMC2724778__F3 | Hypothesis-driven two-factor common pathway model path diagram of the metabolic syndrome |
| PMC2724779__F1 | Complexity of sphingolipid biosynthetic pathways |
| PMC2724780__F1 | Bile acid modulation of death and survival transduction pathways |
| PMC2724975__F6 | Illustrating expansion results with ambiguity networks |
| PMC2724989__F1 | Macrophage activation by endogenous danger signals |
| PMC2725207__F3 | Tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1 |
| PMC2725405__F6 | Regulation of IFN response genes by TLR3 signaling |
| PMC2725943__F7 | A model of mammalian Hh signaling |
| PMC2725945__F1 | Stabilization, degradation, and activation of the Ci/Gli proteins by the Hh signaling pathway |
| PMC2726075__F1 | EGFR signaling pathway |
| PMC2726710__F2 | Intracellular signaling consequences of calpain-mediated substrate cleavage |
| PMC2726720__F3 | Interplay of TGFB, Wnt/Beta-catenin, Hedgehog, and Notch in stem cell differentiation and tumorigenesis |
| PMC2726781__F1 | Retromer sorting pathway is made up of a coat complex that binds and transports transmembrane receptors between the endosome and the trans-Golgi network (TGN) |
| PMC2726954__F2 | Quest for genetic determinants of human longevity: challenges and insights |
| PMC2727126__F1 | Noteworthy, the inhibition of this pathway through COX-inhibitors leads to induction of apoptosis and tumor growth reduction (Figure ) |
| PMC2727282__F7 | Proposed coloboma mechanism in Lrp6-null eyes and a possible signaling network during early eye development |
| PMC2727431__F1 | Various states of pluripotency |
| PMC2727567__F1 | Unwelcome Complement |
| PMC2727709__F1 | Multiple previously established signaling cascades in activated mast cells with quantitative proteomic data from MCP5 cells represented as heatmap bars beside individual proteins |
| PMC2727866__F1 | EGFR-dependent MAPK activation |
| PMC2727867__F1 | Representation of some zinc-induced apoptotic pathways |
| PMC2727884__F2 | Mechanism of action of sorafenib |
| PMC2727910__F1 | Map of arachidonic acid (AA) cascade |
| PMC2727911__F1 | Activation pathways of the complement system and complement regulatory proteins |
| PMC2727921__F1 | Genetic polymorphisms, their allele combinations and IFNB treatment response in Irish multiple sclerosis patients |
| PMC2728081__F2 | Regulation of B-cell entry into the cell cycle |
| PMC2728144__F6 | Schematic diagram depicting our findings on the post-transcriptional regulation of CXCR4 in MCF7-HER2 cells as a result of estrogen and HER2 cross-talk and the involvement of activated PI3K and MAPK pathways and TSC2 (tuberin) |
| PMC2728430__F1 | How ERK1/2 Activation Controls Cell Proliferation and Cell Death Is Subcellular Localization the Answer? |
| PMC2728515__F6 | All-trans retinoic acid promotes neural lineage entry by pluripotent embryonic stem cells via multiple pathways |
| PMC2728746__F7 | Proposed model for the mitogen-activated protein kinase kinase 4 (MEK4) regulation of human prostate cell motility and for its inhibition by genistein |
| PMC2728865__F2 | Transcriptional Regulation of Metabolism Associated With the Increased Desiccation Resistance of the Cactophilic Drosophila mojavensis. |
| PMC2729268__F2 | Map of protein interactivity (binding, regulation, modification) between genes revealed to be significantly associated with bladder cancer in urothelial cell samples |
| PMC2729314__F2 | Wnt signaling network |
| PMC2729321__F3 | Is NFKB a good target for cancer therapy? Hopes and pitfalls |
| PMC2729336__F3 | Transcriptional control of HC and amacrine cell development |
| PMC2729380__F6 | Expression and Functional Studies of Ubiquitin C-Terminal Hydrolase L1 Regulated Genes |
| PMC2729687__F2 | Immunological synapse or the interface between an antigen presenting cell and a T-cell |
| PMC2729812__F1 | Proposed pathway from pressure overload to LV hypertrophy and fibrosis |
| PMC2729932__F2 | ES-EB system has made possible the identification of multipotent progenitors for both hemato-vascular and cardio-vascular derivatives |
| PMC2729995__F1 | Apoptosis and the main anti-apoptotic molecules: Binding of death receptors (Fas, TNF-R, TRAIL-R) to their ligands (Fas-L, TNF, TRAIL) initiates the extrinsic apoptotic pathway |
| PMC2730119__F3 | Scheme showing the role of different signaling pathways in mediating the effect of high K intake on ROMK and BK channels in the CCD |
| PMC2730524__F3 | Translating insights from the cancer genome into clinical practice |
| PMC2730725__F1 | Nm23-H1suppression of tumor metastasis may depend on at least three pathways |
| PMC2730990__F2 | TGFB can leave you breathless |
| PMC2730992__F1 | Cross-species activation of trypanosome S-adenosylmethionine decarboxylase by the regulatory subunit prozyme |
| PMC2731131__F10 | Schematic summary of LPS-triggered programmed cell death in human endothelial cells |
| PMC2731164__F7 | Embryonic Stem Cell Differentiation |
| PMC2731267__F1 | Some putative molecular mechanisms that underlie the antineoplastic activity of mesalazine |
| PMC2731675__F3 | FOLLICULAR HELPER T CELLS: LINEAGE AND LOCATION |
| PMC2731678__F3 | PAK Signaling in Oncogenesis |
| PMC2731733__F5 | Cytoskeletal Remodeling: FAK Signaling pathway is enriched for HeLa and TOV edge hits using PIPA but not node hits using HGA enrichment |
| PMC2732336__F1 | Outline of the major cell surface receptor-mediated signaling pathways important in the differentiation, survival, and function of melanocytes |
| PMC2732416__F5 | Roles of the ILS pathway and HSF1 in aggregation toxicity and longevity |
| PMC2732569__F2 | The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics |
| PMC2733081__F4 | MAPK Signaling Cascade is a Central Hub in the Regulation of Cell Cycle, Apoptosis and Cytoskeleton Remodeling by Tripeptidyl-Peptidase II |
| PMC2733082__F2 | InterferonG signaling pathway and mutations in its components found in human uterine leiomyosarcoma |
| PMC2733092__F4 | Intersection sets of the differentially expressed miRNAs constitute complex interaction networks.A Venn diagram illustrating the production of intersection sets from three miRNA target prediction algorithms |
| PMC2733244__F2 | Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity |
| PMC2733795__F4 | Regulation of STAT3 signal transduction pathway |
| PMC2733936__F1 | Targeting the ASK1/MKK4/JNK pathway upstream of mitochondrial prodeath signaling |
| PMC2734294__F3 | Several molecular features in the cell body of an oxidatively stressed neuron |
| PMC2734563__F2 | Possible mechanisms of UbcH7 regulation of Chk1 levels sand S phase |
| PMC2735047__F3 | Graft-versus-Host Disease |
| PMC2735125__F7 | HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Non-Overlapping Mechanisms |
| PMC2735334__F1 | Carcinogenesis of Bcr-Abl in CML |
| PMC2735462__F3 | Ubiquitin in NFKB Signaling |
| PMC2735600__F7 | Contribution of Rho to canonical Wnt3A signaling |
| PMC2735864__F1 | Genetic Variation in TNF and the NFKB Canonical Pathway and Risk of Non-Hodgkin Lymphoma |
| PMC2735908__F8 | Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway |
| PMC2736107__F2 | In addition to the hypothesis outlined in , a number of other mechanistic pathways could potentially lead to the formation of products 3-5 () |
| PMC2736203__F2 | Impact of a mixed microbial challenge on cell cycle control in HIGK |
| PMC2736291__F2 | Diagram shows the cell signaling pathways, which were involved in postconditioning |
| PMC2736328__F2 | Transcriptional regulation of cytokine function in airway smooth muscle cells |
| PMC2736391__F2 | Simplified model of the leptin signaling pathway |
| PMC2737000__F4 | TNF-induced NFKB and apoptosis pathways |
| PMC2737000__F5 | Arachidonic acid metabolism pathway |
| PMC2737000__F6 | Androgen receptor pathway |
| PMC2737093__F6 | Schematic view of PPARG activation in VSMCs |
| PMC2737270__F1 | Autophagy pathway and machinery.A |
| PMC2737513__F1 | IMP Dehydrogenase: Structure, Mechanism and Inhibition |
| PMC2737689__F2 | Multiple isoforms catalyze each step in the glycerol-3-phosphate pathway of TAG synthesis |
| PMC2737697__F2 | Genetic Susceptibility to Lupus: New Insights from fine mapping and genome-wide association studies |
| PMC2737901__F1 | Putative biosynthetic pathway of PUFAs in Mortierella alpina 1S-4 |
| PMC2738133__F3 | Molecular Aspects of Moraxella catarrhalis Pathogenesis |
| PMC2738707__F1 | Regulatory pathways in hepcidin expression |
| PMC2739091__F8 | Schematics of the effect IL-1B on the alveolar capillary barrier |
| PMC2739295__F6 | Gene Expression Profiling in Cells with Enhanced Gamma-Secretase Activity |
| PMC2739389__F2 | Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape |
| PMC2739389__F3 | Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape |
| PMC2739756__F1 | Bile acid synthesis |
| PMC2739756__F3 | FXR regulation of enterohepatic circulation of bile acid |
| PMC2739756__F4 | FXR-independent and bile acid-activated cell signaling pathways in regulation of CYP7A1 transcription |
| PMC2740411__F8 | Transcriptional regulation of cell cycle arrest gene p21 by ZBTB5 |
| PMC2740793__F2 | TGFB signaling pathway |
| PMC2741134__F2 | Inteferons pen the JAK-STAT pathway |
| PMC2741489__F5 | Known components of the IFN signalling pathway and explanation of observed results |
| PMC2741634__F2 | How location governs Toll like receptor signaling |
| PMC2742086__F2 | Functional and structural organization of migratory mesenchymal cells |
| PMC2742089__F3 | A biochemical pathway of secreted proteins that regulate D-V patterning in Xenopus |
| PMC2742090__F4 | Negative feedback loops in the SHH signaling pathway driven by SHH-binding proteins |
| PMC2742301__F7 | Interactions of Methoxyacetic Acid with Androgen Receptor |
| PMC2742468__F1 | Metabolic cooperativity between oocytes and cumulus cells, and the role of oocyte-derived paracrine factors in promoting metabolism in cumulus cells |
| PMC2742584__F7 | Interaction networks of As sensitivity in yeast |
| PMC2742684__F1 | Key signaling pathways between amino acids, inflammatory cytokines, and tumor-specific factors gr1Amino acids stimulate muscle protein synthesis through the mTOR pathway |
| PMC2742785__F8 | Cluster 2 genes significantly overlapped with those in the eicosanoid signaling pathway (P = 4.6E-05) |
| PMC2743116__F1 | Ras/mitogen-activated protein kinase (MAPK) signaling pathway and associated developmental syndromes (indicated by dashed lines) |
| PMC2743144__F1 | mTORC1 signaling governs hematopoietic stem cell quiescence |
| PMC2743241__F1 | Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents |
| PMC2743272__F1 | Mechanisms underlying the pleiotropic effects of statins in stroke |
| PMC2743399__F3 | Improved readability and performance with multi-scale information integrated in pathway visualization using metagraph |
| PMC2743781__F3 | NAD biosynthetic pathways from nicotinamde and nicotinic acid in yeast, invertebrates, and mammals |
| PMC2743934__F8 | Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD |
| PMC2743935__F5 | Calcium signalling and cell-fate choice in B cells |
| PMC2744278__F3 | Phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling pathways |
| PMC2744356__F1 | Toll-like receptors in skin infectious and inflammatory diseases |
| PMC2744640__F4 | Regulation of Mitochondrial Respiratory Chain Biogenesis by Estrogens/Estrogen Receptors and Physiological, Pathological and Pharmacological Implications |
| PMC2744654__F5 | ProMeTra visualization of relative metabolite pools and transcript abundances during fermentation of the l-lysine producer C |
| PMC2744676__F2 | Diagram depicting proliferative and survival signaling pathways in cells |
| PMC2745153__F2 | Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling |
| PMC2745200__F4 | Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination |
| PMC2745384__F6 | RCAN1 mediated regulation of cell proliferation and apoptosis: Schematic shows that GC-dependent GR activation and subsequent MAP kinase-dependent phosphorylation enables GR binding to GRE sequences on target genes |
| PMC2745643__F1 | Beta-catenin signaling and its regulation |
| PMC2745765__F3 | Linking the MGI and MouseCyc databases |
| PMC2745891__F6 | Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mTOR activity and p27Kip1 localization |
| PMC2746202__F1 | Pathway from PI3K to TOR |
| PMC2746238__F2 | Induction of autoimmunity by pristane and other naturally-occurring hydrocarbons |
| PMC2746245__F2 | Toll-like receptor (TLR) pathway |
| PMC2746245__F6 | Injury-induced changes in the nociceptive pathway |
| PMC2746247__F1 | Pathway Engineered Enzymatic de novo Purine Nucleotide Synthesis |
| PMC2746747__F1 | Molecular ablation of TGFB signaling pathways by tyrosine kinase inhibition: The coming of a promising new era in the treatment of tissue fibrosis |
| PMC2746948__F1 | Apoptosis pathway |
| PMC2747008__F12 | Induction of IFNB and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7 |
| PMC2747034__F1 | MTDH/AEG-1 promotes tumor progression through the integration of multiple signaling pathways |
| PMC2747168__F1 | Acp-group transfer catalyzed by PhTYW2 |
| PMC2747343__F1 | Ingenuity pathway analysis shows 17 genes from the 180 genes associated with the NF-E2-related factor-2 (NRF-2)-mediated oxidative stress response pathway |
| PMC2747759__F1 | Monoclonal antibodies in the treatment of pancreatic cancer |
| PMC2747760__F1 | Leptin signaling: A key pathway in immune responses |
| PMC2748726__F1 | Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas |
| PMC2748802__F18 | Hypothesized descending pathway for translating emotional states or appetitive need for food, salt or water into goal-directed motor tasks |
| PMC2749258__F3 | Approaches to biomarkers in human colorectal cancer |
| PMC2749259__F2 | Hypothetical diagram of possible sites of action of non-opioids in the regulatory pathway of IL-6 |
| PMC2749270__F1 | Sphingosine-1-phosphate synthesis and functions in mast cells |
| PMC2749448__F1 | Transcriptional Regulation of Carbohydrate Metabolism in the Human Pathogen Candida albicans |
| PMC2749675__F1 | Scheme of the Wnt signaling pathway |
| PMC2749695__F4 | Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target |
| PMC2749695__F5 | Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target |
| PMC2749725__F1 | Coverage of the insulin receptor signaling pathway |
| PMC2749862__F5 | Most prominently affected gene network in response to DEX in TM 86 cells |
| PMC2749862__F6 | Most prominently affected gene network in response to FA in TM 93 cells |
| PMC2749881__F1 | Proposed mechanism for formation of Hb monoadducts and cross-links derived from the S-oxidase and Beta-lyase metabolic pathways of DCVC |
| PMC2750148__F2 | NFKB signal transduction |
| PMC2751538__F7 | Proposed VEGF-C/D cell signaling pathway to transduce LAM cell proliferation |
| PMC2751986__F7 | Rev-erbA/PGC-1A pathway regulating heme homeostasis |
| PMC2751999__F6 | LPA effect and signal transduction pathway |
| PMC2752022__F2 | FoxO factors in endothelial cells |
| PMC2752022__F3 | Akt-FoxO pathway in regulation of heart size |
| PMC2752361__F3 | MOLECULAR CONSTITUTION OF BREAST BUT NOT OTHER REPRODUCTIVE TISSUES IS RICH IN GROWTH PROMOTING MOLECULES |
| PMC2752373__F1 | Selected transformation pathways of tamoxifen and the main CYP enzymes involved |
| PMC2752535__F4 | Common features of host-Flaviviridae interactions |
| PMC2752832__F7 | Scheme for up-regulation of the PAI-1 gene by EGF in glioblastoma |
| PMC2752847__F1 | Type I interferon production by dendritic cells in host defense |
| PMC2753670__F3 | Integration of ITAM and cytokine Jak-STAT signaling |
| PMC2753833__F4 | Transition to endocycles in Drosophila |
| PMC2753863__F1 | Examination of Association of Genes in the Serotonin System to Autism |
| PMC2754046__F1 | Hypothetical schematic of a DAergic synapse |
| PMC2754156__F3 | LPS signal transduction via the MyD88-dependent pathway |
| PMC2754156__F4 | LPS signal transduction via the MyD88-independent pathway |
| PMC2754444__F5 | T-Cell Activation Pathways Generated by HIV-Modulated Proteins |
| PMC275444__F7 | Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility |
| PMC2754694__F1 | Transcriptional regulation of human CYP17 |
| PMC2754696__F1 | CIE and CDE pathways showing lipid content and regulatory molecules |
| PMC2754915__F1 | Schematic illustration of different pathways of glucose metabolism in cancer cells |
| PMC2754915__F3 | Signalling events which determine glucose utilization within the cell |
| PMC2754932__F6 | Model of Udu function in DNA damage response |
| PMC2755611__F1 | Regulation of aging: does autophagy underlie longevity? |
| PMC2755790__F1 | Network analysis of differentially expressed proteins (red symbols) involved in arteriogenesis |
| PMC2755866__F9 | Diagram for the non-canonical MEK/ERK signaling pathway regulating autophagy via regulating Beclin 1 |
| PMC2756021__F3 | Neuroprotective Effects of the Complement Terminal Pathway During Demyelination: Implications for Oligodendrocyte Survival |
| PMC2756025__F1 | The polyamine metabolic pathway |
| PMC2756045__F2 | LKB1-AMPK pathway: metabolism and growth control in tumor suppression |
| PMC2756045__F3 | LKB1-AMPK pathway: metabolism and growth control in tumor suppression |
| PMC2756045__F4 | LKB1-AMPK pathway: metabolism and growth control in tumor suppression |
| PMC2756058__F1 | Pathway of cellular processing of cobalamin (OH-cbl) and location of main enzyme defects in the pathway leading to methylmalonic acidemias and cobalamin metabolic disorders |
| PMC2756316__F5 | Proposed model for the interaction between PyVmT and IR or IGF-IR |
| PMC2756331__F1 | Trk receptor tyrosine kinases and major signal transduction pathways |
| PMC2756474__F7 | CREB Mediates Prostaglandin F2Alpha-Induced MUC5AC Overexpression |
| PMC2756491__F8 | PPARA/p16INK4a Pathway inhibits Vascular Smooth Muscle Cell Proliferation by repressing Cell Cycle-dependent Telomerase Activation |
| PMC2756538__F3 | A model for the role of eEF-2K in the induction of autophagy during amino acid starvation and ER stress |
| PMC2756670__F3 | Potential mechanisms of estrogen-mediated signaling through estrogen receptor (ESR) and G protein-coupled receptor 30 (GPR30) |
| PMC2756670__F4 | The proposed model underlying the potential lithogenic mechanisms of estrogen through the estrogen receptor 1 (ESR1) pathway in the liver |
| PMC2756763__F1 | Aromatase: synthesis of estrogen in postmenopausal women and its inhibition by aromatase inhibitors |
| PMC2756767__F2 | Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer |
| PMC2756767__F3 | Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer |
| PMC2756960__F8 | Effect of DLK1 and RTL1 but Not MEG3 or MEG8 on Muscle Gene Expression in Callipyge Lambs |
| PMC2757047__F3 | Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity |
| PMC2757120__F1 | Canonical PI3K signaling pathway |
| PMC2757135__F1 | Cholesterol transport in steroid biosynthesis: Role of protein-protein interactions and implications in disease states |
| PMC2757186__F9 | Working model for the biochemical cascade leading to the AR |
| PMC2757227__F1 | Regulation of ENaC and CFTR by SGK1/Nedd4-2 |
| PMC2757291__F6 | The SLAM-Associated Protein (SAP)/Fyn/PKCθ Pathway is Required for Thymocyte-mediated CD4 T Cell Development |
| PMC2757293__F2 | Innate immune evasion by hepatitis C virus and West Nile virus |
| PMC2757632__F1 | O-GlcNAc cycling: Implications for Neurodegenerative disorders |
| PMC2757648__F3 | Interferon response genes are coordinately upregulated relative to the rs17445836[G] allele of IRF8 |
| PMC2757699__F1 | Metabolic fate of the 13C-label from [1-13C]-glucose |
| PMC2757940__F2 | Major components of FGF and HH signaling pathways |
| PMC2757945__F9 | Molecular pathways by which WNT-Beta-Catenin and FGF regulate lung mesenchymal development |
| PMC2757955__F10 | Proposed model of IGFBP-3 modulation of growth factor receptor activation mediated by S1P |
| PMC2758233__F2 | P75NTR-mediated signal transduction pathways |
| PMC2758290__F1 | The SIAE (sialic acid acetylesterase)-Siglec pathway for inhibitory signaling |
| PMC2758293__F2 | An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: A biochemical and molecular perspective |
| PMC2758485__F1 | Wnt/PCP signaling and its effects on organogenesis |
| PMC2758524__F7 | Increased radio-resistance and accelerated B-cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA damage-activated kinases |
| PMC2758611__F6 | Schematic presentation of the proposed TGFB signaling alteration that promotes HNSCC in mice |
| PMC2758708__F2 | Diagrammatic representation of non-canonical Wnt signalling in a mammalian cell |
| PMC2759052__F1 | Signal transduction pathway mediated by epidermal growth factor receptor (EGFR) |
| PMC2759127__F5 | Hypothetical mechanism of glucose sensing in the heart in response to hemodynamic or metabolic stress |
| PMC2759143__F2 | Distinct signaling pathways induced by A2(IV)NC1 |
| PMC2759143__F3 | Different signaling pathway mediated by A3(IV)NC1 |
| PMC2759144__F4 | Model depicting the E2Fs-FA/BRCA axis in the control of cell fate |
| PMC2759177__F3 | Survival signals generated by PI3K and PLD that target mTOR |
| PMC2759942__F5 | Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity. |
| PMC2759974__F1 | MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer |
| PMC2760069__F1 | Brothers and Sisters: Molecular insights into arterial-venous heterogeneity |
| PMC2760340__F2 | Representation of NF1 interactions with the Ras and PI3K pathways |
| PMC2760836__F2 | New concepts in herpes simplex virus vaccine development: notes from the battlefield |
| PMC2760938__F13 | Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase CD, Lyn Kinase, and Matrix Metalloproteinases |
| PMC2761008__F2 | Minimum spanning tree of the network associated with cancer pathway genes |
| PMC2761008__F3 | Cliques or near cliques from the cancer pathway related network Gp |
| PMC2761106__F8 | BMP7 signaling in the NZ |
| PMC2761108__F8 | Roles of BMP signaling pathways during SNS development |
| PMC2761115__F2 | Gonad function and sexual differentiation |
| PMC2761207__F1 | Major pathway of the conversion of propionyl-CoA into succinyl-CoA in human cells |
| PMC2762009__F1 | The Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders |
| PMC2762102__F5 | Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis |
| PMC2762604__F11 | Proteomic and Phospho-Proteomic Profile of Human Platelets in Basal, Resting State: Insights into Integrin Signaling |
| PMC2762706__F3 | Hypoxia signaling pathway in DM patients 4d post-CPB/C |
| PMC2762943__F1 | Epidermal growth factor receptor (EGFR) pathway |
| PMC2762943__F3 | P53 pathway |
| PMC2763047__F2 | The Fibroblast Growth Factor Receptor Signaling Pathway in Non-Small Cell Lung Cancer. |
| PMC2763047__F3 | Fibroblast Growth Factor Receptor Signaling Pathway as a Mediator of Intrinsic Resistance to EGFR-specific Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer |
| PMC2763495__F1 | Metabolic pathways of growth and proliferation |
| PMC2763495__F4 | AMPK-p53 pathway in metabolic adaptation |
| PMC2763507__F1 | Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses |
| PMC2763943__F2 | Nox proteins in signal transduction |
| PMC2764428__F4 | MiRNA/TF-mediated regulatory pathway associated with tumorigenesis |
| PMC2764635__F1 | The EGF activated ERK pathway: This is a schematic of the EGF activated ERK pathway beginning at the level of EGF binding to EGFR and finishing at the level of ERK; see the text for more details on the features and functions of the pathway |
| PMC2764635__F3 | New model of EGF activated ERK pathway: This is a schematic of our new model of the EGF activated ERK pathway which was developed from the original [] EGF model |
| PMC2764635__F7 | Experimental results of Rap1 pathway knockout from Falco et al |
| PMC2764635__F8 | Comparison of growth factor receptor signalling: This figure shows a comparison of ERK signalling from the EGF and Insulin receptors |
| PMC2765277__F3 | Scheme of part of the central metabolism of E |
| PMC2765277__F5 | Amino acid producing elementary flux patterns |
| PMC2765788__F6 | STRIATAL NEUROPROTECTION WITH METHYLENE BLUE |
| PMC2765790__F7 | Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes |
| PMC2766052__F8 | The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation |
| PMC2766659__F4 | Signaling molecules and pathways regulating the fate of spermatogonial stem cells |
| PMC2766677__F7 | Proposed scheme of the signaling pathway leading to immature dendritic cell chemotaxis upon exposure to M-tropic gp120 |
| PMC2766863__F2 | Signalling crosstalk in B cells: managing worth and need |
| PMC2766922__F2 | Signaling pathways downstream of HVEM, LIGHT, and their binding partners are shown |
| PMC2767105__F2 | Intracellular ascorbate (Asc) modulates redox-sensitive signaling pathways in microvascular endothelial cells during sepsis |
| PMC2768039__F2 | Genetic Basis for Kidney Cancer. |
| PMC2768066__F8 | Thrombospondin-1-CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO-cGMP pathway activation |
| PMC2768486__F10 | Possible mechanism by which BMPs and estrogen regulate GNRH production by GT1-7 cells |
| PMC2768529__F8 | Proposed interplay between IL-15 and TNFA signaling in skeletal muscle |
| PMC2768581__F2 | Role of Cross Talk between PI3-Kinase and ERK/MAP Kinase Pathways in Artery-Vein Specification |
| PMC2768836__F1 | Role of clathrin adaptor proteins in melanosome biogenesis |
| PMC2768990__F2 | BANs of differentially expressed genes in common between cell lines |
| PMC2768997__F1 | Human protein-protein interaction network of aging-associated genes |
| PMC2769052__F9 | Schematic representation of a potential mechanism of IFN-Gamma- and STAT3-dependent cell growth modulated by TSC2/mTOR signaling pathway |
| PMC2769196__F4 | Acromegaly pathogenesis and treatment |
| PMC2769198__F2 | Smad4: gatekeeper gene in head and neck squamous cell carcinoma |
| PMC2769199__F8 | Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice |
| PMC2769250__F3a | Trafficking of Heme and Porphyrins in Metazoa |
| PMC2769253__F1 | MicroRNAs in cancer |
| PMC2769253__F3 | MicroRNAs in cancer |
| PMC2770326__F2 | Mammalian sialic acid metabolism |
| PMC2770326__F4 | Pathway options for sialic acid glycoengineering |
| PMC2770326__F6 | Selective pathway utilization of analogs is ensured by the nonpermissivity of enzymes at critical junctures |
| PMC2770656__F4 | The tyrosine metabolism pathway where the differentially expressed genes of lung cancer were annotated |
| PMC2770887__F1 | ER stress-induced signaling pathways that mediate autophagy |
| PMC2770888__F2 | Targeting EGFR resistance networks in Head and Neck Cancer |
| PMC2771153__F9 | Schematic presentation of a model of induction of beta cell apoptosis during viral infections |
| PMC2771222__F1 | Recent reports have suggested that the Hedgehog (Hh) pathway is activated in lesional psoriatic skin (; ; ; ), and that pharmacological inhibition of this pathway using cyclopamine may lead to rapid resolution of the disease (; ; ) |
| PMC2771360__F4 | Microglia Are Mediators of Borrelia burgdorferi-Induced Apoptosis in SH-SY5Y Neuronal Cells |
| PMC2771724__F3 | Dopamine Receptor Signaling: Genes differentially expressed in the NAC of LE vs |
| PMC2771724__F4 | Synaptic Long-Term Potentiation: Genes differentially expressed in the NAC of LE vs |
| PMC2771939__F1 | Spatial Segregation of Phosphatidylinositol 4,5-Bisphosphate (PIP2) Signaling in Immune Cell Functions |
| PMC2772137__F4 | Temporal Profiling of Rat Transcriptomes in Retinol-Replenished Vitamin A-Deficient Testis |
| PMC2772702__F6 | The PI3k/Akt signaling pathway depicting the possible sites of action by the PI3k inhibitors LY294002 and wortmannin and the Akt inhibitors Akt-VIII, Akt-V, and Akt-IV |
| PMC2772826__F1 | Apoptosis in animal models of virus-induced disease |
| PMC2772842__F1 | Major mechanisms of leukocyte cell loss in AIDS |
| PMC2773299__F2 | Schematic representations of the activated RAS-MAPK, RASSF1A/NORE1A, and Dab2IP/ASK1 pathways, iNOS signalling, and FOXM1-related pathways involved in the dysregulation of cell growth and apoptosis in HCC |
| PMC2773416__F6 | Diagrammatic representation of intracellular pathways that lead to the production of IL-12p40 and the mechanisms of azithromycin (AZM) to inhibit the expression of IL-12p40 upon the stimulation of LPS/IFNG |
| PMC2773630__F6 | Molecular interactions during pheromone induced cell polarization |
| PMC2773638__F4 | Coordination of extracellular and intracellular signaling regulates cytoskeletal dynamics and axon formation |
| PMC2773646__F1 | Nodal signaling pathway |
| PMC2773711__F1 | Canonical TCR signaling pathway |
| PMC2773833__F3 | Drivers of senescence and therapeutic opportunities in WS and HGPs |
| PMC2773962__F6 | Model of Tbx2 function for the EC formation in the AVC |
| PMC2774072__F7 | Proposed consequences of impaired insulin signaling in AD brain and in the STZ-injected rat brain |
| PMC2774076__F7 | Current working model of the signaling pathway components (shaded areas) that are differentially regulated in C57 and CD-1 pup brain tissues and cultured NSCs under normoxic and hypoxic (Hx) conditions |
| PMC2774487__F2 | Pathway showing genes involved in Parkinson's disease (Courtesy: KEGG pathway) |
| PMC2774576__F1 | Diagram illustrating the biosynthetic pathway of n-3 and n-6 fatty acids from dietary precursors |
| PMC2774738__F3 | Specification of cell fate in the mammalian cochlea |
| PMC2774752__F1 | Puzzles, promises and a cure for ageing |
| PMC2774770__F1 | IL-4 induces an alternate pathway for BCR signalling |
| PMC2774790__F6 | Proteome Profile of Functional Mitochondria from Human Skeletal Muscle Using One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS |
| PMC2774854__F1 | Schematic overview about TCR-dependent signalling pathways |
| PMC2774878__F2 | The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. |
| PMC2775047__F1 | TLR Mediated Immune Responses in the Urinary Tract |
| PMC2775119__F3 | Ciliary functions of cystoproteins: mechanosensation and cell cycle control |
| PMC2775177__F1 | Branches of the UPR signalling pathway |
| PMC2775236__F1 | The effect of neuronal activity on the function of the miR379-410 cluster member miR-134 |
| PMC2775805__F6 | Molecular pathway analysis of genes regulated in the NAc by the HDAC inhibitor MS-275 after chronic social defeat stress |
| PMC2775888__F2 | Cellular mechanisms by which flavonoids and their metabolites protect against neuroinflammation and neuronal injury induced by 5-S-Cys-DA, DHBT-1 and related ROS |
| PMC2775948__F2 | Integrated Proteomic Analysis of Human Cancer Cells and Plasma from Tumor Bearing Mice for Ovarian Cancer Biomarker Discovery |
| PMC2776288__F2 | Crosstalk between ionizing radiation-induced apoptosis and NFKB pathway |
| PMC2776288__F3 | Crosstalk between apoptosis and NFKB signaling by IAP-antagonist |
| PMC2776679__F7 | Egr-1 and Hipk2 are required for the TrkA to p75NTR switch that occurs downstream of IGF1-R |
| PMC2776723__F6 | Integration of activated transcription factors with the upstream signaling network during CB1R-induced neurite outgrowth |
| PMC2776748__F1 | A, Schematic diagram showing intra-cellular functions of the Bcl family of proteins |
| PMC2776915__F1 | A genetic model for sex determination, controlled by a balance of antagonistic pathways |
| PMC2777122__F2 | Step 2: T-cell activation and costimulation |
| PMC2777340__F4 | Drosophila insulin signaling pathway |
| PMC2777383__F1 | Predictive Phosphorylation Signature of Lung Cancer |
| PMC2777399__F1 | Regulatory mechanism of the Rho/ROCK pathway activated by angiotensin II (ANG II) in vascular smooth muscles cells (VSMCs, see text) |
| PMC2777484__F1 | Folate-mediated 1-carbon metabolism |
| PMC2777795__F2 | Negative-feedback loop linking NAD+/SIRT1 with the Clock network |
| PMC2778015__F3 | Master regulator miRNA of oncogenic and tumor suppressor |
| PMC2778230__F3 | Apoptotic signaling in aging muscles |
| PMC2778287__F6 | Schematic representation of a dualistic model depicting the development of ovarian cancer |
| PMC2778342__F2 | Roles of the selected genes in the DSBR pathway |
| PMC2778660__F6 | Network representation of p53, NFKB and cell cycle interactions |
| PMC2778684__F1 | Canonical and non-canonical Wnt signaling pathways |
| PMC2778737__F4 | Nephron development and cell lineages |
| PMC2778955__F10 | Expression of an IKKG Splice Variant Determines IRF3 and Canonical NFKB Pathway Utilization in ssRNA Virus Infection |
| PMC2779044__F4 | Model describing the regulation of protein synthesis by AMPK, Ca++ and Akt -signaling pathways |
| PMC2779188__F1 | Genes involved in the vitamin D pathway |
| PMC2779759__F7 | Schematic model illustrating how Jun proteins regulate the TIMP-3, TACE, and TNFA pathway: Jun proteins transcriptionally activate TIMP-3 expression, which is responsible for TACE inhibition |
| PMC2780394__F7 | The signaling network of differentially expressed proteins |
| PMC2780838__F1 | The complement cascade |
| PMC2780914__F3 | Transmigration causes differential expression of genes in the apoptosis pathway |
| PMC2781055__F3 | Ingenuity pathway analysis (IPA) of microarray data generated several genetic networks |
| PMC2781329__F4 | Schematic diagram for HO-1 modulation of signaling pathway and adiponectin, EET levels, and vascular function |
| PMC2781394__F8 | HGF-mediated inhibition of gluconeogenesis in primary hepatocytes |
| PMC2781439__F7 | Speculative model depicting mono-ubiquitination-dependent and independent functions of the FA-BRCA pathway in DNA replication-associated repair processes |
| PMC2781509__F1 | Folate-mediated one-carbon metabolism |
| PMC2781822__F2 | Resolution of immune activation defines nonpathogenic SIV infection |
| PMC2782081__F1 | An overview of miRNA biogenesis |
| PMC2782433__F1 | COPPER ACTIVATION OF NFKB SIGNALING IN HEPG2 CELLS |
| PMC2782452__F1 | Different views of the Akt pathway/network |
| PMC2782488__F1 | Cytokine signaling modules in inflammatory responses. |
| PMC2782488__F3 | Cytokine signaling modules in inflammatory responses |
| PMC2782644__F5 | Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs |
| PMC2782690__F3 | Is cancer a disease of abnormal cellular metabolism? |
| PMC2782725__F2 | Cell cycle and acute kidney injury |
| PMC2782733__F2 | EGFR signaling through the PI3K/Akt pathway |
| PMC2783241__F2 | Kidney development: from ureteric bud formation to branching morphogenesis |
| PMC2783351__F2 | "Toll" of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia |
| PMC2783472__F1 | Impaired DNA Damage Response - an Achilles' Heel Sensitizing Cancer to Chemotherapy and Radiotherapy |
| PMC2783472__F2 | Impaired DNA Damage Response - an Achilles' Heel Sensitizing Cancer to Chemotherapy and Radiotherapy |
| PMC2783518__F1 | Wnt signaling and senescence: a tug of war in early neoplasia? |
| PMC2783576__F2 | Mitotic removal of cohesin in humans: In humans, cohesins (pink) are removed from chromosome arms in prophase in a Plk1-dependent pathway |
| PMC2783774__F4 | miRNA process pathway |
| PMC2783837__F2 | TRAIL-R1/-R2 apoptotic signaling pathway |
| PMC2783859__F3a | Identification of Actively Translated mRNA Transcripts in a Rat Model of Early Stage Colon Carcinogenesis |
| PMC2783967__F6 | Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin |
| PMC2784025__F8 | Proposed model of the underlying mechanism by which NeuroD6 may bridge neuronal differentiation to survival |
| PMC2784121__F6 | NPM-ALK oncogenic tyrosine kinase controls T cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells |
| PMC2784255__F1 | Examination of Tetrahydrobiopterin Pathway Genes in Autism |
| PMC2784308__F1 | An illustration of the MC1R pigmentation pathway and the loci implicated in melanoma risk |
| PMC2784662__F1 | mTOR Signaling Cascade |
| PMC2784766__F3 | Complex role of the PLAU-PLAUR pathway in the airways |
| PMC2784807__F1 | IL-10 and IL-6 signaling pathways among 2,102 DEG due to IMI with Streptococcus uberis |
| PMC2784807__F3 | Cyclin-dependent kinase (CDK) 5 (A) and Insulin-like growth factor (IGF)-1 signaling pathways (B) among 2,102 differentially expressed genes due to intramammary infection with Streptococcus uberis |
| PMC2784807__F5 | Ingenuity Pathway Analysis® network depicting relationships among genes involved in immune and metabolic responses due to IMI with Streptococcus uberis |
| PMC2784899__F7 | Model to account for responsiveness to cAMP level in activation but not inactivation of eumelanin synthesis |
| PMC2785127__F5 | Putative targets of common changes in gene expression with single and repeated IMO stress |
| PMC2785342__F8 | A proposed model for HA-CD44-mediated PKCE activation and Nanog signaling in the regulation of miRNA-21 production, oncogenesis, and chemoresistance in breast tumor cells |
| PMC2785474__F2 | TLR signaling (an example in macrophages and dendritic cells) |
| PMC2785474__F4 | TLR4 and chemokine receptor cross-talk |
| PMC2785475__F4 | Expression-Based Network Biology Identifies Alteration in Key Regulatory Pathways of Type 2 Diabetes and Associated Risk/Complications |
| PMC2785495__F3 | Response of heterogeneous ribonuclear proteins (hnRNP) to ionizing radiation and their involvement in DNA damage repair |
| PMC2785525__F1 | The Anticoagulant APC Pathway |
| PMC2785525__F2 | Cytoprotective APC pathway |
| PMC2785619__F2 | Up-regulation of TGFB signaling in Timp3-/--AB hearts |
| PMC2785637__F1 | Schematic overview of hepatic lipid biosynthetic pathways |
| PMC2785769__F7 | Proposed pathways for promotion (A) and progression genes (B) influenced by TLR4 |
| PMC2785881__F3 | Sialic Acid Utilisation and Synthesis in the Neonatal Rat Revisited |
| PMC2785932__F3 | Four pathways by which the EBV latent membrane protein 1 (LMP1) is thought to signal inside cells |
| PMC2786169__F4 | Topology of leukemia-related BCR-ABL pathway |
| PMC2786705__F8 | Continued defect in IRF-3-deficient BMDCs |
| PMC2786808__F8 | Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice |
| PMC2786873__F9 | Model of amino acid starvation-induced AARE-dependent transcription in human cells |
| PMC2787458__F9 | Wnt3a stimulates Src docking to, activation by, and phosphorylation of Dvl2 |
| PMC2787631__F7 | Working model of PKA's role in trastuzumab resistance |
| PMC2787666__F1 | Base excision repair (BER) pathway |
| PMC2787666__F2 | The complex network of protein-protein interactions of Ape1 |
| PMC2787730__F10 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the focal adhesion pathway |
| PMC2787730__F11 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the apoptosis pathway |
| PMC2787730__F12 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the cell-adhesion pathway |
| PMC2787730__F9 | TNF- A-inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the cytokine and cytokine-receptor interaction pathway |
| PMC2787898__F1 | TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice |
| PMC2788007__F1 | Simplified representation of the complement cascade |
| PMC2788021__F3 | A model for torpor induction in mammals that links reduced availability of food in the environment with the energy status of the cell, the mammalian circadian clock, and response to oxidative stress |
| PMC2788154__F1 | Signaling pathways that lead from activated KIT and aggregated FcERI to mast cell responses |
| PMC2788159__F1 | Regulation of mTORC1 mTORC1 is a multiprotein complex composed of Raptor, mLST8, PRAS40, and FKBP38 and regulates protein synthesis and cell growth by phosphorylating S6K1 and 4EBP1 |
| PMC2788159__F2 | Current proposed mechanisms of amino acid sensing by mTORC1 Amino acids are imported into the cells via various amino acid transporters and activate mTORC1 either by amino acid metabolites or by undefined membrane/intracellular amino acid sensor(s) |
| PMC2788213__F4 | Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages |
| PMC2788255__F6 | Wnt signalling pathway downregulated in osteosarcoma |
| PMC2788512__F7 | Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway. |
| PMC2788597__F3 | Metabolic pathway of pitavastatin |
| PMC2788936__F3 | Signaling and regulation of PRR-induced autophagy |
| PMC2789270__F1 | TGFB: A New Role for an Old AktTOR |
| PMC2789271__F1 | Gene selection in the TGFß signaling pathway |
| PMC2789488__F3 | Schema of major signaling pathways involved in renal development (for space and clarity, not all factors in each pathway shown) |
| PMC2789670__F5 | Summary of glutathione (l-Gamma-glutamyl-l-cysteinylglycine, GSH) homeostasis pathway identified in C |
| PMC2789784__F2 | Signaling pathway downstream of PI3K affect cell death and cell survival |
| PMC2789789__F6 | Scheme of the biosynthesis pathways for PC, PE, and PS in human P |
| PMC2790076__F5 | Comparative Analysis of Gene Expression Patterns and Cell Phenotypes between Cervical and Peripheral Blood Mononuclear Cells |
| PMC2790152__F3 | A model of the inhibitor of growth (ING) 2 signaling pathway |
| PMC2790217__F17 | Akt regulates growth by phosphorylating and inhibiting the TSC1-TSC2 complex in drosophila |
| PMC2790273__F1 | Possible cross-talk between Nod2, TCR, Cd28, TLR and TNFR family members in regulating NFKB |
| PMC2790404__F2 | Viral infection elicits a variety of antiviral cellular responses |
| PMC2790417__F10 | Summary of proposed role for Foxa2, Nodal and Hh signalling pathways in ventral CNS development |
| PMC2790539__F1 | Apoptosis in cerebral ischemia and reperfusion |
| PMC2790720__F2 | IRF4: Immunity. Malignancy! Therapy? |
| PMC2790753__F1 | Microarray data for the genes in the pathway coined from the central genes in the KEGG pathways 'insulin signaling pathway' and 'adipocytokine signaling pathway' |
| PMC2790850__F2 | Aberrant Myc expression causes mammary cancer |
| PMC2791157__F3 | Decomposition of Gene Expression State Space Trajectories |
| PMC2792482__F3 | Integration of lipid metabolic and inflammatory signaling in macrophages by LXRs |
| PMC2792912__F6 | Model of Six2 function during mouse pyloric sphincter development |
| PMC2793049__F2 | Leptin signaling and leptin resistance |
| PMC2793058__F10 | IFNG signaling pathway in retinal pigment epithelium |
| PMC2794539__F5 | Gene Expression Signature of Invasive Potential in Metastatic Melanoma Cells |
| PMC2794543__F8 | Activation of Wnt/Beta-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells |
| PMC2794560__F1 | Metabolic pathways of tamoxifen |
| PMC2794709__F2 | O-GlcNAc and phosphate regulate the insulin signaling pathway at the plasma membrane |
| PMC2795248__F3 | Anti-inflammatory effects of EPAC in VECs |
| PMC2795398__F1 | Endotoxin binds to CD14 and Toll-like receptor 4 (TLR4) on the surface of monocytes and endothelial cells |
| PMC2795439__F1 | Androgen-receptor signalling in normal prostate and PCa |
| PMC2795506__F5 | Dopamine D1–D2 receptor heteromer signaling pathway |
| PMC2796113__F2 | Models of Merlin-dependent membrane receptor distribution in flies and mammalian cells |
| PMC2796172__F2 | Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics |
| PMC2796182__F4 | Regulation of nitric oxide signaling by thrombospondin-1: implications for anti-angiogenic therapies |
| PMC2796203__F1 | Targeting the Transforming Growth FactorB Signaling Pathway in Human Cancer |
| PMC2796203__F2 | Targeting the Transforming Growth FactorB Signaling Pathway in Human Cancer |
| PMC2796930__F7 | FGF-receptor signalling in the generation of hindbrain neural cell diversity |
| PMC2796982__F3 | Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway |
| PMC2796989__F1 | Interleukin (IL)-13/transforming growth factor (TGF)B signalling pathways |
| PMC2797270__F8 | Summary of Trif-biased signaling and selective p38 activation by sMLA |
| PMC2797318__F2 | Promising bone-related targets for rheumatoid arthritis therapy |
| PMC2797409__F3 | Reconstructed CCM of S |
| PMC2797439__F1 | Class IA PI3K signalling pathway |
| PMC2797892__F10 | Pathway induction after pathophysiologic stimulation of BSMC by three coordinate stimuli: strain, hypoxia, and damaged matrix |
| PMC2798195__F9 | Proposed mechanism for pathogenesis due to H |
| PMC2798273__F1 | Role of CobT in the late steps of AdoCbl biosynthesis |
| PMC2798676__F10 | Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling |
| PMC2798710__F1 | New roles for Notch in tuberous sclerosis |
| PMC2799380__F6 | Connective tissue associated signalling network common to various cardiac hypertrophy animal models and human cardiac disease |
| PMC2799800__F1 | Scheme of the model for the mammalian cell cycle |
| PMC2799977__F2 | TLR signaling upon intrinsic cellular defenses |
| PMC2800175__F2 | Comparing the core structures of 1 and 4, biosynthesis of the naphthacenecarboxamide carbon frameworks of 1 is predicted to parallel that of the oxytetracycline (oxy) biosynthetic pathway, and may share a number of common intermediates |
| PMC2800820__F1 | Multiple pro-inflammatory mediators in the tumor microenvironment increase the accumulation of MDS cells and enhance their immunosuppressive activity |
| PMC2800957__F1 | Targets for lithium's neuroprotective effects |
| PMC2801177__F3 | Subnetworks of select putative DEP-regulated gene transcripts show an enrichment of inflammatory response |
| PMC2801177__F4 | Identification of candidate molecular network for miRNAs most highly changed in response to DEP |
| PMC2801237__F5 | Proposed revised model of mammalian DNA damage response |
| PMC2801257__F1 | Signaling through the Lymphocyte receptor induces a novel regulatory motif for MAP kinase activation |
| PMC2801289__F1 | UDP-galactose synthesis in L |
| PMC2801624__F1 | A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches |
| PMC2801866__F1 | VEGF binding to VEGFR2 on endothelial cells activates its Tyr kinase activity and results in autophosphorylation of the receptor at several cytoplasmic sites |
| PMC2801866__F3 | Thrombospondin-1 (TSP1) binds to two receptors on endothelial cells that inhibit NO signaling |
| PMC2801866__F4 | NO/cGMP pathway is a signaling node for pro- and anti-angiogenic signaling |
| PMC2802426__F1 | Molecular mechanisms that regulate ionotropic glutamate receptor distribution during hippocampal mGluR-LTD induction and expression |
| PMC2802426__F2 | Schematic model of molecular mechanisms underlying regulation of gene transcription and protein translation during mGluR-LTD in postsynaptic neurons of hippocampal CA3-CA1 synapses |
| PMC2803240__F8 | Model of VA metabolism in neonatal rat lung |
| PMC2803288__F4 | Schematic diagram depicting the pathway via which GC-A signaling inhibits cardiac hypertrophy |
| PMC2803786__F2 | Network analysis of the top 250 predictor genes |
| PMC2804071__F4 | Joubert syndrome: insights into brain development, cilium biology and complex disease |
| PMC2804114__F1 | IR and IGF family signaling pathway |
| PMC2804177__F9 | The signaling pathways regulating osteoblast-like cells proliferation in response to OSS |
| PMC2804818__F5 | A summary of the ligand-mediated control of TRP53 expression via the PI3 kinase/AKT/MDM2 pathway |
| PMC2805009__F1 | Cross-talk between TCR and TGFB signaling networks |
| PMC2805044__F1 | The Akt/mTOR pathway in tobacco-carcinogen induced lung tumorigenesis |
| PMC2805259__F5 | Hypothetical model for how the translational control checkpoint is disabled in human lung cancer |
| PMC2805399__F8 | A proposed working model of the complex Sertoli cell-germ cell interaction describing the mechanism by which Sertoli cells trigger germ cell apoptosis following MEHP-induced Sertoli cell injury |
| PMC2805685__F11 | Reconstruct part of KEGG pathway by our method |
| PMC2805706__F3 | Brain foods: the effects of nutrients on brain function |
| PMC2805793__F1 | Ligand binding and subsequent Erbb dimer formation initiates signaling through a complex array of intracellular pathways that initiate and control a range of cellular processes |
| PMC2805916__F1 | Galectins, integrins and cell migration |
| PMC2806029__F2 | Ammonia detoxification pathway and mitochondrial sirtuins |
| PMC2806113__F6 | Working model of TGFB actions in renal interstitial fibrogenesis |
| PMC2806300__F8 | Reversal of EMT induced by TGFB1 |
| PMC2806370__F2 | Cell cycle pathway gene expression |
| PMC2806370__F3 | Pathway deregulation in ovarian cancer |
| PMC2806519__F8 | Prostaglandin F2Alpha-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway |
| PMC2806747__F1 | TLR4 signaling pathway can be activated via GAG fragments requiring CD44 and MyD88 or through LPS, which requires MyD88, LBP, and CD14 |
| PMC2806892__F1 | Methionine metabolism in vivo |
| PMC2807132__F2 | p38 signaling to the chromatin in muscle progenitor cells |
| PMC2807212__F2 | Hh and Wnt signaling pathways |
| PMC2807212__F3 | TGFB superfamily and FGF signaling pathways |
| PMC2807318__F8 | Summary of the AMPK and mTOR signaling pathways |
| PMC2807379__F4 | Nephronophthisis: Disease Mechanisms of a Ciliopathy |
| PMC2807379__F6 | Nephronophthisis: Disease Mechanisms of a Ciliopathy |
| PMC2807379__F8 | Nephronophthisis: Disease Mechanisms of a Ciliopathy |
| PMC2808051__F1 | Summary of the insulin/IGF signaling pathway, using the terminology for mammalian systems |
| PMC2808051__F20 | Reversible phosphorylation regulation of the cell cycle |
| PMC2808051__F6 | Mammalian target of rapamycin (mTOR) activation pathway |
| PMC2808058__F1 | Schematic of the Notch pathway |
| PMC2808058__F2 | The effects of the SOX4 and HOXC6 transcriptional networks on PI3K-AKT pathway activation in prostate cancer |
| PMC2808058__F3 | The effects of SOX4 and HOXC6 on Notch pathway activation and metastasis |
| PMC2808140__F2 | Pathogenic Bacterial Proteins and their Anti-Inflammatory Effects in the Eukaryotic Host |
| PMC2808158__F7 | Schematic summary of effect of IL-4 priming on phagocytic and secretory capacities of MΦs |
| PMC2808176__F1 | Example of pathway segments corresponding to FALZ identified from breast cancer data (Figure drawn with Cytoscape) |
| PMC2808241__F7 | Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice |
| PMC2808316__F5 | Metabolic model for Aspergillus niger |
| PMC2808370__F7 | Possible mechanism by which Wnt determines the specificity of signalling pathway |
| PMC2808458__F1 | Toll-like receptor signaling in cell proliferation and survival |
| PMC2808458__F2 | Toll-like receptor signaling in cell proliferation and survival |
| PMC2809500__F4 | Proteins upregulated during time course analysis in lung or bronchoalveolar lavage fluid (BAL) following intra tracheal instillation of 20 µg carbon nanopaticles (CNP) |
| PMC2809778__F2 | Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, Parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis |
| PMC2809919__F2 | Epithelial-mesenchymal interactions mediated by the Sonic Hedgehog pathway in the gut |
| PMC2810075__F6 | CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts |
| PMC2810084__F7 | TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice |
| PMC2810142__F9 | Network diagram of Sp1-interacting proteins |
| PMC2810291__F6 | Endonuclein functions |
| PMC2810358__F2 | Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas |
| PMC2810404__F6 | Hepatocyte expression of Serum Response Factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice |
| PMC2810486__F1 | The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections. |
| PMC2810509__F2 | BIOLOGY OF VASCULAR MALFORMATIONS OF THE BRAIN |
| PMC2810509__F3 | BIOLOGY OF VASCULAR MALFORMATIONS OF THE BRAIN |
| PMC2810550__F2 | Wnt signaling pathway involvement in cancer and neurodegeneration |
| PMC2810615__F1 | Simplified overview of the canonical Wnt/Beta-catenin signaling pathway |
| PMC2810618__F8 | Signaling network model for heart valve development and remodeling |
| PMC2810629__F1 | Tale of Transforming Growth FactorB (TGFB) Signaling: A Soigné Enigma |
| PMC2810660__F1 | Autophagy and NFKB fight for fate |
| PMC2811067__F2 | Some of the stress response transcription factor pathways with homologs in N |
| PMC2811176__F2 | Cytosine Methylation Dysregulation in Neonates Following Intrauterine Growth Restriction |
| PMC2811231__F7 | Gene program of neutrophil recruitment and tissue injury based on gene expression and in vitro data |
| PMC2811646__F3 | Molecular targets in Nrf2/phase II enzymes pathway modulated by PEITC and SFN |
| PMC2811646__F4 | Molecular targets in NFKB pathway modulated by PEITC and SFN |
| PMC2811741__F7 | Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model |
| PMC2812385__F7 | Alternative mechanisms exist for the induction of inflammatory and apoptotic genes in the absence of the IFNA/B receptor during influenza virus infection |
| PMC2812596__F2 | Target genes, Gnas, Got2 and Snord32a, following tenofovir exposure of primary osteoclasts |
| PMC2812679__F8 | TK-mediated signaling pathway promoting HaCaT keratinocyte migration |
| PMC2812698__F1 | Signalling pathways that regulate cell wall remodelling of Candida albicans |
| PMC2812788__F1 | HDL, ABCA1 and ABCG1 transporters in cholesterol efflux and immune responses |
| PMC2813054__F1 | Changes in Akt signaling with differentiation of CD8+ T cells and co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1)-blocked highly differentiated CD8+ T cells |
| PMC2813229__F4 | Pathway analysis result showing 18 differentially expressed proteins following 50% PH can be sorted into the c-myc pathway |
| PMC2814006__F1 | IL-1 and TNF signal transduction events |
| PMC2814179__F1 | Therapeutic targeting of NOTCH1 signaling in T-ALL |
| PMC2814417__F7 | The postulated signaling of MAP kinase pathway in proliferating or differentiating HL60 cells |
| PMC2814418__F8 | VDR-dependent and auxiliary pathways that lead to deltanoid-induced monocytic differentiation of myeloid leukemia cells |
| PMC2814429__F2 | Regulation of autophagy and apoptosis |
| PMC2814453__F1 | Coupling between Akt-mediated cellular energy metabolism, cell survival and proliferation |
| PMC2814543__F4 | Nutrient sensing and inflammation in metabolic diseases |
| PMC2814769__F5 | Primary Cilium as a Complex Signaling Center |
| PMC2815016__F3 | Farnesol induces ER stress and activation of the unfolded protein response |
| PMC2815016__F4 | Activation of the NFKB signaling pathway by farnesol is related to ER stress |
| PMC2815088__F4 | The Hexosamine Signaling Pathway |
| PMC2815088__F5 | Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine |
| PMC2815088__F6 | Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine |
| PMC2815132__F1 | Dopamine Synthesis Pathway: Dopamine's synthesis pathway begins with the amino acid tyrosine and is regulated by the activity of tyrosine hydroyxylase |
| PMC2815188__F2 | This presentation will focus on molecular mechanisms underlying transduction of BCR signals that enforce the antigen unresponsiveness of anergic B cells |
| PMC2815894__F2 | Network of ABA-induced stomatal closure |
| PMC2816010__F6 | Effect of dasatinib on the BCR-ABL signaling pathway |
| PMC2816026__F7 | Met signal transduction exploited by InlB from L |
| PMC2816169__F6 | Prokineticin (PROK1) induction of regulator of calcineurin 1 isoform 4 (RCAN1-4) and interleukin (IL-11) |
| PMC2817017__F2 | RAS-RAF-MEK-ERK signaling pathway |
| PMC2817383__F4 | Putative host signaling pathway induced by Y |
| PMC2817430__F1 | Phylogenomics of Sterol Synthesis: Insights into the Origin, Evolution, and Diversity of a Key Eukaryotic Feature |
| PMC2817557__F2 | Molecular Modulation of Intestinal Epithelial Barrier: Contribution of Microbiota. |
| PMC2817888__F3 | ATM/ATR DNA damage response pathway and its downstream effectors leading to either G1/S or G2/M phase arrest |
| PMC2818158__F1 | Inflammation at a molecular level: a simplified scheme |
| PMC2818223__F2 | GSK3 regulation of STATs, Smads, Beta-catenin, and NFAT |
| PMC2818233__F2 | Nuclear phosphoinositide-mediated stress response pathway |
| PMC2818238__F1 | Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates intracellular calcium signaling by different mechanisms |
| PMC2818240__F5 | Oxidative stress and glutathione in TGF-Beta-mediated fibrogenesis |
| PMC2818318__F4 | Regulation of Cell Cycle and RNA Transcription Genes Identified by Microarray Analysis of PC-3 Human Prostate Cancer Cells Treated with Luteolin |
| PMC2818736__F1 | Colorectal cancer (CRC) stem cell model |
| PMC2818872__F8 | Ras signaling in early B cell development |
| PMC2819006__F1 | Key mechanisms involved in colorectal carcinogenesis |
| PMC2819049__F3 | Different components of shelterin are dedicated to different aspects of the end-protection problem |
| PMC2819159__F2 | Obesity, Diet and Risk of Non-Hodgkin Lymphoma |
| PMC2819165__F2 | Genetic Susceptibility to Lymphoma |
| PMC2819219__F7 | Caspase Mediated Cleavage, IAP Binding and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NFKB Signaling |
| PMC2819346__F1 | Hepatic Overexpression of Glycerol-sn-3-phosphate Acyltransferase 1 in Rats Causes Insulin Resistance |
| PMC2819352__F6 | Relationship of GPAT4 to other enzymes in the pathway of de novo glycerolipid synthesis |
| PMC2819585__F7 | MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis |
| PMC2819730__F1 | Urine-based assays for the detection of bladder cancer |
| PMC2819754__F1 | Transcriptional regulation of the differentiation of Th1 cells |
| PMC2819754__F2 | Transcriptional regulation of the differentiation of Th2 cells |
| PMC2819802__F1 | Activation of apoptotic and survival pathways by TNF |
| PMC2820080__F4 | Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE |
| PMC2820080__F5 | Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE |
| PMC2820199__F3 | Network of proteins, functional classes and cell processes modulated in prostate cancer cells after curcumin treatment |
| PMC2820199__F4 | Curcumin's targets intracellular components implicated in cell proliferation signaling pathway in prostate cancer cells |
| PMC2820234__F3 | Suggested signaling of the early stages of 1,25D-induced monocytic differentiation |
| PMC2820251__F1 | Innate immune evasion strategies of influenza viruses |
| PMC2820251__F2 | Innate immune evasion strategies of influenza viruses |
| PMC2820418__F12 | PRG5 signaling in axon growth and neurite retraction |
| PMC2820477__F1 | Schematic junctional organization and Beta-catenin signaling in CNS ECs: comparison of brain and retina |
| PMC2820477__F2 | Scheme of known Wnt pathways |
| PMC2820587__F3 | AURKA interactions |
| PMC2820658__F1 | Induction of IFNs after virus infection in IFNB pretreated human DCs |
| PMC2820725__F4 | Redox signaling responses in DCs and T cells during T cell activation |
| PMC2820748__F6 | Sites within the early steps of the insulin signaling pathway affected by OGT and O-GlcNAcylation |
| PMC2820927__F3 | Model illustrating the dynamic overlapping phases of early events of KSHV infection in endothelial and fibroblast cells and KSHV-induced signal pathways and their role in infection |
| PMC2821201__F6 | A diagrammatic model to summarize the role and subcellular localization of survivin and its splice variants in the regulation of apoptosis and control of mitosis in cancer cells |
| PMC2821476__F3 | TNFA induced signaling |
| PMC2821718__F3 | Structure and signalling in the IL-17 receptor superfamily |
| PMC2821954__F2 | Portrayed here is a molecular pathway analysis of genes regulated in the mouse nucleus accumbens by a direct infusion of the HDAC inhibitor MS-275 after chronic social defeat stress |
| PMC2821977__F1 | All steroids derive from cholesterol, which can be synthesized within the brain for de novo neurosteroidogenesis () |
| PMC2822054__F1 | How the PI3K-AKT and MEK-ERK pathways regulate apoptosis in EGFR driven cancers |
| PMC2822437__F1 | Heterotrimeric G Proteins and Apoptosis: Intersecting Signaling Pathways Leading to Context Dependent Phenotypes |
| PMC2822520__F7 | A working model for endosomal transport involving CLC-5 and KIF3B interaction in polarized cells |
| PMC2822851__F1 | Signal transduction pathway from integrin receptors to actin cytoskeleton |
| PMC2822937__F7 | Downstream effectors of the ErbB receptor signalling pathway |
| PMC2822975__F1 | Asbestos has pleiotropic effects on cell signaling pathways |
| PMC2823977__F1 | REACTIVE OXYGEN SPECIES, CELLULAR REDOX SYSTEMS AND APOPTOSIS |
| PMC2824068__F1 | Complement Factors and their G Protein Coupled Receptors in Neuroprotection and Neurodegeneration |
| PMC2824626__F1 | Pathway for cholesterol synthesis from 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) by HMG CoA reductase and its inhibition by statins |
| PMC2824633__F4 | Cyclin D3-specific deregulated genes and their functional networks |
| PMC2824707__F1 | Tissue level and signalling pathways for PGE2 is presented |
| PMC2824740__F5 | Strain-induced quantitative mRNA-expression analysis of PDL cells related to MAP-kinase signalling and cell cycle, ECM and integrins, and growth factor pathways |
| PMC2824768__F4 | Entry into an ICL repair pathway depends on the mode of recognition |
| PMC2824905__F2 | IFITM Proteins Mediate the Innate Immune Response to Influenza A H1N1 Virus, West Nile Virus and Dengue Virus |
| PMC2825293__F2 | Nutrient sensing machinery in K- and L-cells |
| PMC2825553__F1 | Interplay of cellular stress signals with apoptosis pathways |
| PMC2825767__F1 | Adrenal insulin signaling and glucose transport gene expression is overexpressed in the chromogranin A (Chga) knockout mouse |
| PMC2825767__F2 | Adrenal cholesterol biosynthesis pathway gene expression is globally underexpressed in the Chga knockout mouse |
| PMC2825767__F3 | Hepatic cholesterol biosynthesis pathway gene expression is globally overexpressed in the Chga knockout mouse |
| PMC2826040__F4 | miR-200a is implicated in the type I interferon signaling pathway |
| PMC2826040__F5 | miR-223 is implicated in the CREB signaling pathway |
| PMC2826212__F2 | An intricate gene regulatory network controls OL differentiation |
| PMC2826517__F1 | The current understanding of PELP1 signaling pathway |
| PMC2826542__F1 | An Overview of IL-7 Biology and Its Use in Immunotherapy |
| PMC2826554__F1 | Beta-AR-dependent translation initiation |
| PMC2826600__F4 | Insulin and IGF1 signaling pathway to promote glucose uptake by GluT3 in neurons (shown) or GlutT4 in muscle (not shown) |
| PMC2826677__F1 | T-cell activation, proximal signalling complex and activation of transcription factors |
| PMC2827416__F5 | Impact of high dietary protein on lipid metabolism in porcine adipose tissue at body weight 60 kg |
| PMC2827416__F6 | Impact of high dietary protein on lipid metabolism in porcine adipose tissue at body weight 100 kg |
| PMC2827616__F8 | Signaling pathways controlling ENS precursor migration and lamellipodia formation |
| PMC2827926__F3 | The refined scheme of the glyoxylate regeneration cycle, now termed ethylmalonyl-CoA pathway (right), and its connection to the serine cycle (left) |
| PMC2827930__F2 | The Core Notch Signaling Pathway is mediated by regulated proteolysis |
| PMC2828057__F1 | Genetic factors influencing cytarabine therapy |
| PMC2828273__F1 | Interconnections between p53 and IGF-1/AKT/mTOR pathways |
| PMC2828280__F2 | Canonical Wnt pathway |
| PMC2828612__F1 | Putative mechanism by which the UPS acts downstream of BDNF/TrkB signaling to ultimately regulate Alpha-synuclein aggregation |
| PMC2829054__F7 | Cdk2 Is Required for p53-Independent G2/M Checkpoint Control |
| PMC2829061__F7 | Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair |
| PMC2829067__F1 | Caspase-1 Activation via Rho GTPases: A Common Theme in Mucosal Infections? |
| PMC2829367__F1 | Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy. |
| PMC2829627__F2 | Tumor-associated angiogenesis is sustained through stromal microenvironment crosstalk |
| PMC2829627__F3 | PPARG agonists inhibit Stat3-mediated IL-6 gene expression in myeloma cells |
| PMC2830120__F3 | Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection |
| PMC2830320__F1 | Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptors |
| PMC2830572__F1 | TNF A inhibits erythropoiesis by direct and indirect effects |
| PMC2830938__F1 | Role of oxidative stress and DNA repair proteins in cells |
| PMC2830959__F3 | Genetic alterations of the Ras-dependent ERK1/2 pathway in cancer |
| PMC2830970__F1 | Schematics of the retroviral replication cycle |
| PMC2831005__F10 | Yeast cell cycle |
| PMC2831042__F7 | Proposed model of neurite outgrowth pathway in postnatal SVZ/RMS-derived neurons |
| PMC2831127__F7 | Proteins Secreted By Embryonic Stem Cells Activate Cardiomyocytes Through Ligand Binding Pathways |
| PMC2831232__F2 | NKT cells in immune-mediated pregnancy loss |
| PMC2831538__F3 | Autophagy regulation in response to stress |
| PMC2831839__F9 | A proposed mechanism of MNTX synergistic effects with temsirolimus on inhibition of VEGF-induced angiogenic events |
| PMC2832126__F1 | The multi-stage autophagic process |
| PMC2832144__F11 | Proposed model for the signal transduction pathways involved in TGFB1-mediated fibroblast-myofibroblast differentiation |
| PMC2832169__F6 | Interaction between sFRP4 and the Wnt signaling pathway |
| PMC2832191__F3a | Regulation of autophagy induction in yeast and mammalian cells |
| PMC2832236__F5 | BS and M chloroplast distribution of proteins involved in primary carbon metabolism |
| PMC2832309__F2 | WWOX gene and gene product: tumor suppression through specific protein interactions |
| PMC2832675__F1 | Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement |
| PMC2832691__F3 | Binding of Herpes Simplex Virus Type-1 Virions Leads to the Induction of Intracellular Signalling in the Absence of Virus Entry |
| PMC2832838__F1 | CONVERTING HUMAN PLURIPOTENT STEM CELLS INTO BETA CELLS: RECENT ADVANCES AND FUTURE CHALLENGES |
| PMC2832945__F7 | Proposed mechanism for B2M mAb inhibition of AR and cell proliferation, survival, and progression through a MAPK/SREBP-1 signaling pathway in prostate cancer cells |
| PMC2833108__F6 | Sonic Hedgehog, Wnt and TGFB signaling pathway gene expression in CpG late treated macrophages [; ; ; ], see discussion |
| PMC2833108__F7 | TNFSFR and NFKB signaling activation during macrophage activation: CpG late responses |
| PMC2833197__F7 | Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway |
| PMC2833311__F6 | Signaling pathways involved in Alpha-TEA-induced apoptosis in human ovarian cancer cell lines |
| PMC2833340__F1 | Plane facts of PCP in the CNS |
| PMC2834195__F1 | The circadian clock signaling pathway |
| PMC2834246__F2 | Regulation of chromatin structure by drugs of abuse |
| PMC2834303__F9 | PI3K-Akt pathway negatively regulates LPS signaling and gene expression in mouse macrophages by inhibiting the activation of MAPKs |
| PMC2834432__F1 | Phosphatidylinositol 3-kinase (PI3K) signaling cascade |
| PMC2834467__F2 | Map showing relationship between genes positively correlated with plasma estradiol superimposed on Ingenuity map |
| PMC2834542__F5 | Actin cytoskeleton signaling pathway as represented by Ingenuity Pathway Analysis |
| PMC2834552__F11 | Schematic diagram of AGE-induced CTGF expression is shown |
| PMC2834616__F4 | EGR3 and miRNAs involving in signaling pathways and regulatory networks in schizophrenia and nervous system |
| PMC2834757__F9 | Upregulation of SOCS-3 and PIAS-3 Impairs IL-12-Mediated Interferon-Gamma Response in CD56+ T Cells in HCV-Infected Heroin Users |
| PMC2834833__F3 | GSK3: a multifaceted kinase in Wnt signaling |
| PMC2834863__F1 | Transforming growth factor beta (TGFB) and inflammation in cancer |
| PMC2835321__F6 | Retrograde mechanisms in NMJ formation |
| PMC2835492__F4 | Regulation of MUC4 expression |
| PMC2835842__F1 | HSV-1-mediated antagonism of TLR-dependent, anti-viral pathways |
| PMC2835907__F3 | Synopsis of FGFR2b-mediated dermal-epithelial signaling in keratinocytes and sebocytes of sebaceous glands |
| PMC2836046__F7 | Proposal of the regulatory loop of miR-24, miR-34a, and HNF4A in bile acid synthesis |
| PMC2836122__F2 | Cytokine signaling through the JAK/STAT pathway |
| PMC2836529__F3 | Neurotrophin actions on the endothelial cell |
| PMC2836783__F2 | CD62L regulation by T-cell receptor (TCR) stimulation and Gc-cytokines |
| PMC2837270__F8 | Seoul virus suppresses NFKB-mediated inflammatory responses of antigen presenting cells from Norway rats |
| PMC2837360__F1 | Canonical Wnt/Beta-catenin pathway (modified after ()) |
| PMC2837572__F1 | Downstream signalling pathways of TNFA |
| PMC2837572__F2 | An overview of the signalling pathways mediated by TNFA in metastasis |
| PMC2837947__F2 | Disruption of metabolic pathways involved in fat pad mass trait in mouse models of the candidate genes |
| PMC2837985__F9 | Proposed model for the regulatory mechanisms of the Ras and cAMP signaling pathways in stress response and antifungal drug susceptibility in C |
| PMC2838081__F10 | Molecular pathways regulated by C/EBPB during E-induced proliferation of uterine epithelial cells |
| PMC2838200__F3 | Proposed scheme for how macrophage-based nanoparticle drug delivery could affect disease outcomes in neurodegenerative disorders |
| PMC2838317__F8 | Differences between TRAIL- and AD5-10-induced signaling pathways |
| PMC2838378__F1 | Simplified schematic of the IgE receptor (FcERI) signaling pathway |
| PMC2838378__F2 | Simplified schematic of the T cell receptor signaling pathway |
| PMC2838843__F3 | PTEN signaling pathway |
| PMC2839169__F1 | Simplified illustration of the epidermal growth factor receptor (EGFR) pathway with the RAS/MAPK and PIK3CA/PTEN cascades |
| PMC2839260__F1 | Schematic depiction of the signalling pathways stimulated by cholecystokinin (CCK) activation of the CCK1 receptor |
| PMC2839261__F1 | Effector pathways stimulated by Beta-ARs |
| PMC2839263__F2 | Emerging models for the role of Beta-arrestin in wingless (from Drosophila) and the oncogene int-1 (WNT) signalling |
| PMC2839281__F4 | Pigmentation Pathway Evolution after Whole-Genome Duplication in Fish |
| PMC2839454__F2 | Too Old to Fight? Aging and its Toll on Innate Immunity |
| PMC2840045__F1 | Innate immune responses in allotransplantation |
| PMC2840099__F7 | Proposed model of miR-486 regulation and function in muscle cells |
| PMC2840158__F6 | Schematic showing cytoplasmic signaling pathway from ATM to TSC2 via LKB1 and AMPK to repress mTORC1 and induce autophagy |
| PMC2840206__F1 | Action of metformin |
| PMC2840217__F6 | Antioxidant and phase II detoxifying enzyme genes in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells |
| PMC2840217__F7 | Changes in cell cycle regulation in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells |
| PMC2840217__F8 | Alteration in Ubiquitin-Proteasome System (UPS) in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells |
| PMC2840217__F9 | Parkinson's disease (PD)-related gene pathway in response to MG132, methylmercury (MeHg), and cadmium (Cd) in MEF cells |
| PMC2840235__F1 | Blockade of the VEGF pathway with mAbs |
| PMC2840262__F2 | Autophagy and the Ubiquitin-Proteasome System in Cardiac Dysfunction |
| PMC2840670__F1 | K-ras mutation governs the effects of inhibition of epidermal growth factor receptor (EGFR) on the Ras/Raf/Mek signaling pathway |
| PMC2841057__F1 | Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension |
| PMC2841057__F4 | Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension |
| PMC2841246__F4 | COX-2 inhibitors on apoptosis |
| PMC2841319__F1 | Pathogenesis of kidney disease in systemic lupus erythematosus |
| PMC2841320__F6 | ZIP4 Regulates Pancreatic Cancer Cell Growth by Activating IL-6/STAT3 Pathway via Zinc Finger Transcription Factor CREB |
| PMC2841329__F1 | Model for the role of ÃŽâ€Np73B in the DDR |
| PMC2841835__F1 | Host defence signaling pathways in Caenorhabditis elegans model |
| PMC2842081__F1 | Telomeres: protecting chromosomes against genome instability |
| PMC2842130__F9 | Redoxosomal signaling for IL-1B and TNFA pathways |
| PMC2842492__F2 | Transcripts regulating the mammalian cell cycle are up-regulated in the proliferative-phase endometrial epithelium |
| PMC2842525__F2 | IFNA signal transduction |
| PMC2842986__F2 | General synthetic route to the racemic vinyl, ethyl, n-propyl, n-butyl, i-butyl, 2-propenyl, allyl, ethynyl, and 1-propynyl mevalonate lactone analogues (1a–e, g, i–k) is shown in |
| PMC2843003__F3 | Epicardial-Myocardial Signaling Directing Coronary Vasculogenesis. |
| PMC2843167__F7 | Summary of the findings presented here |
| PMC2843172__F8 | Schematic drawing summarizing the signaling pathway downstream from CB1 receptors in cerebellar granule cell precursors |
| PMC2843459__F11 | Schematic diagram illustrating the proposed signaling pathway involved in LTA-induced cPLA2/COX-2-dependent airway inflammation |
| PMC2843693__F2 | Molecular Origins of Cancer |
| PMC2844056__F2 | Ingenuity pathway analysis and expression profiles of genes involved in apoptosis that were uniquely up regulated in ER+ cells in response to EPA |
| PMC2844056__F5 | Ingenuity pathway analysis of genes up regulated in ER+ cell in response to AA shows that the ERK/MEK pathway was significantly associated with ER+ |
| PMC2844056__F6 | Insulin receptor cascade was uniquely up regulated in ER- cells when treated with AA |
| PMC2844056__F7 | Genes involved in cell-cell signaling significantly associated with ERbreast cancer cells in response to AA |
| PMC2844177__F9 | P38 MAPK signal transduction in melanogenesis |
| PMC2844217__F1 | Schematic representation of the biosynthetic pathway of emetine, cephaeline, and related alkaloidal glucosides in P |
| PMC2844310__F3 | Relationship of NFKB to genes identified as "linearly" changing with age on the basis of cocitation analysis (Genomatix BibliosphereTM) is shown as a Bibliosphere image |
| PMC2844426__F4 | Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS) |
| PMC2844640__F1 | Role of Radiation-induced TGF-beta Signaling in Cancer Therapy |
| PMC2844640__F3 | Role of Radiation-induced TGF-beta Signaling in Cancer Therapy |
| PMC2844927__F3 | Routes of interaction between epoxyeicosanoid and endocannabinoid signaling pathways |
| PMC2845642__F2 | Molecular Mechanisms of T cell Receptor and Costimulatory Molecule Ligation/Blockade in Autoimmune Disease Therapy |
| PMC2845723__F2 | The bile salt synthetic pathway |
| PMC2846056__F3 | Making the blastocyst: lessons from the mouse |
| PMC2846061__F3 | Ovary: basic biology and clinical implications |
| PMC2846071__F1 | Prevention trumps treatment of antibody-mediated transplant rejection |
| PMC2846156__F3 | Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer |
| PMC2846630__F1 | Regulation of the mTOR pathway by nutrients (amino acids, glucose), stress and insulin/IGF-1 |
| PMC2846691__F1 | Pathways initiated by ACSL, FATP, and ACSBG isoforms |
| PMC2847023__F3 | Vitamin D3-driven signals for myeloid cell differentiation - Implications for differentiation therapy |
| PMC2847412__F1 | Endoplasmic reticulum stress response as a potential therapeutic target in multiple sclerosis |
| PMC2847476__F3 | Immunoregulatory Functions of mTOR Inhibition |
| PMC2847521__F11 | Proposed model for the I3C disruption of a cross-regulatory positive feedback loop involving expression of GATA3 and ERA by stimulating the degradation of ERA protein |
| PMC2848014__F8 | Proteomics Reveals Novel Oxidative and Glycolytic Mechanisms in Type 1 Diabetic Patients' Skin Which Are Normalized by Kidney-Pancreas Transplantation |
| PMC2848030__F6 | How the presence of virus acts on innate immune system components, i.e |
| PMC2848237__F2 | Reconstruction of a KEGG pathway |
| PMC2848307__F1 | Survival pathways with their cross-talk and immune regulatory mechanisms are shown in this pictorial representation of the Reed-Sternberg (R-S) cell |
| PMC2849133__F4 | Main targets of RhoA and ROCK, involved in organization of the cytoskeleton |
| PMC2849646__F3 | Frequent amplification and overexpression of multiple EGFR-family-signaling components in non-small cell lung cancer (NSCLC) |
| PMC2849704__F1 | Homocysteine metabolism in liver and kidney |
| PMC2849832__F1 | IFNG signaling through the JAK/STAT1 pathway |
| PMC2849843__F1 | Schematic presentation of PI3K-Akt signaling |
| PMC2849843__F2 | Schematic presentation of Akt-mTOR signaling |
| PMC2849853__F5 | Regulation of the Hypothalamic Thyrotropin Releasing Hormone (TRH) Neuron by Neuronal and Peripheral Inputs |
| PMC2850388__F7 | Dkk4 and Eda Regulate Distinctive Developmental Mechanisms for Subtypes of Mouse Hair |
| PMC2850399__F7 | Mevalonate pathway and the pleiotropic effects of statins |
| PMC2850427__F2 | Simplified Overview of the Purine Metabolism PathwayThe scheme is derived from KEGG Pathways hsa00230 (purine metabolism) and hsa00240 (pyrimidine metabolism) |
| PMC2850885__F7 | Proposed model of a EGFR/Beta-catenin/cyclin D1 signaling pathway in oral cancer |
| PMC2851161__F1 | The Notch signaling pathway |
| PMC2852112__F1 | Scheme of the autophagy pathway |
| PMC2852112__F2 | Anti-viral and pro-viral functions of autophagy |
| PMC2852400__F7 | Inhibition of the Proprotein Convertases Represses the Invasiveness of Human Primary Melanoma Cells with Altered p53, CDKN2A and N-Ras Genes |
| PMC2852570__F1 | Semaphorin signaling |
| PMC2852600__F2 | CD40 responsiveness in Leishmania-infected macrophages: crosslinking of anti-CD40 antibody activates p38 MAPK-induced leishmanicidal function via iNOS2 induction |
| PMC2852602__F2 | TLR/IL-1R signalling pathways |
| PMC2853371__F9 | CD28 costimulation, IL-2 signaling, and mTOR pathway regulate Otub1 and GRAIL expression, controlling proliferation in primary naive CD4 T cells |
| PMC2853417__F5 | Differentially expressed genes in the TGFB signaling pathway |
| PMC2853417__F6 | Differentially expressed genes in the ERK/MAPK signaling pathway |
| PMC2853417__F7 | Differentially expressed genes in the estrogen receptor signaling pathway |
| PMC2853973__F1 | Kaposi's sarcoma-associated herpesvirus and innate immunity |
| PMC2854141__F9 | Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease |
| PMC2854193__F1 | Autophagy Genes as Tumor Suppressors |
| PMC2854204__F1 | TOR-dependent control of autophagy: biting the hand that feeds |
| PMC2854249__F1 | Mammalian autophagy: core molecular machinery and signaling regulation |
| PMC2854249__F2 | Mammalian autophagy: core molecular machinery and signaling regulation |
| PMC2854285__F1 | mTOR and cancer: many loops in one pathway |
| PMC2854285__F2a | mTOR and cancer: many loops in one pathway |
| PMC2854298__F8 | AATF mediates anti-apoptotic effect of the unfolded protein response through transcriptional regulation of AKT1 |
| PMC2854301__F9 | The Transcriptional Repressor REST/NRSF modulates Hedgehog Signaling |
| PMC2854308__F1 | Signaling complexes induced by TNFA to mediate NFKB activation, apoptosis and necroptosis |
| PMC2854673__F1 | Minimally oxidized LDL induces TLR4-dependent lipoprotein uptake by macrophages |
| PMC2855089__F2 | NFKB Signaling Pathway |
| PMC2855202__F3 | Cross-talk between the hexosamine biosynthesis pathway, O-GlcNAc modification of proteins, signaling events downstream of insulin action, and glucose-induced adipocytokine secretion |
| PMC2855642__F2 | Glycosylation of Alpha-dystroglycan |
| PMC2855646__F7 | Summary of biosynthetic pathway for O-mannosyl glycans on A dystroglycan in mammals |
| PMC2855687__F1 | The kynurenine pathway with relevant regulatory components, summarizing gene expression and metabolite changes previously identified for schizophrenia in the frontal and anterior cingulate cortex |
| PMC2856263__F6 | Signaling pathways activated by DMXAA |
| PMC2856329__F9 | Brx-mediated osmotic stress-activated signaling system and its implications for the immune response |
| PMC2856448__F1 | Opposing influences on Foxo cellular localization and transcriptional activity |
| PMC2856528__F1 | The three complement activation pathways, converging to cleave C3 |
| PMC2856637__F1 | Simplified scheme of early FcERI-mediated signaling events |
| PMC2856676__F1 | Comparative Genomics of Flowering Time Pathways Using Brachypodium distachyon as a Model for the Temperate Grasses |
| PMC2856775__F1a | Convergence of Pathways in TLR and IL-1R SignalingUpon activation, the IL-1 receptor dimerized with the IL-1 receptor accessory protein |
| PMC2856809__F3 | Dual MAG receptor model |
| PMC2856900__F7 | Moe and Rho1 function in apoptosis based on genetic, biochemical, and subcellular localization data |
| PMC2857022__F7 | Mechanistic model of KLF11-mediated tumor suppression and its antagonism by an oncogenic pathway |
| PMC2857099__F6 | Proposed model for NFKB repression by TRAF3 in LTBR activation |
| PMC2857169__F5 | NFKB in conventional T-cell activation |
| PMC2857176__F3 | Map of selected p53 pathway-associated genes that harbor known or potential functional SNPs (octagon-shaped boxes) and their closely interacting genes (rectangular boxes) |
| PMC2857179__F1 | Mechanisms and pathways targeted by mutations in MPN |
| PMC2857326__F7 | TGFB induces apoptosis in human B cells via transcriptional regulation of BIK and BCL-XL |
| PMC2857646__F1 | Schematic of the TGFB signaling pathway |
| PMC2857869__F4a | Metabolic Engineering for Production of Biorenewable Fuels and Chemicals: Contributions of Synthetic Biology |
| PMC2858157__F6 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858157__F7 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858157__F8 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858157__F9 | Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration |
| PMC2858431__F1 | Developing Antiepileptogenic Drugs for Acquired Epilepsy: Targeting the Mammalian Target of Rapamycin (mTOR) Pathway |
| PMC2858440__F5 | Four flux sensors of the in silico cell |
| PMC2858442__F3 | Model of CD95-mediated signaling |
| PMC2858523__F1 | Schematic diagram showing the RAS-MAPK signal transduction pathway and affected disease genes in disorders of the neurocardiofacialcutaneous syndrome family |
| PMC2858611__F3 | Depiction of the "Reelin signalling in neurons" pathway generated by Ingenuity |
| PMC2858667__F1 | Endocannabinoids Differentially Modulate Synaptic Plasticity in Rat Hippocampal CA1 Pyramidal Neurons |
| PMC2858867__F1 | ALPS - Ten Lessons from an International Workshop on a Genetic Disease of Apoptosis |
| PMC2858906__F1 | Main steps and key regulators in blood and lymphatic vasculature development |
| PMC2859139__F1 | Immunoregulatory pathways |
| PMC2859499__F7 | TAK1·TAB2·NLK complex negatively regulating canonical Wnt pathway |
| PMC2859933__F9 | Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-Infected Brain: Novel Analysis of Retrospective Cases |
| PMC2860204__F4 | Integrin signalling at focal adhesions |
| PMC2860235__F7 | FunCoup subnetwork of candidate cancer gene RPA1 surrounded by functionally coupled known cancer genes |
| PMC2860273__F2 | Regulation of HIF-dependent and -independent pathways by Siah2 on tumorigenesis and metastasis |
| PMC2860309__F1 | EDA signaling |
| PMC2860348__F1 | p38 MAPK mediates the transcriptional response to stress |
| PMC2860379__F2 | Genes affecting dystroglycan glycosylation associated with congenital muscular dystrophy |
| PMC2860555__F1 | Endosomal and cytoplasmic pathways for virus recognition and IFN production |
| PMC2860693__F8 | Simplified model of the signaling pathways regulating radiation-induced bystander effects |
| PMC2860895__F1 | TOM1L2 and genes associated with Alzheimer's disease in the human interactome |
| PMC2860937__F1 | Caveat mTOR: aberrant signaling disrupts corticogenesis |
| PMC2861144__F1 | Novel targets for the treatment of autosomal dominant polycystic kidney disease |
| PMC2861144__F2 | Novel targets for the treatment of autosomal dominant polycystic kidney disease |
| PMC2861286__F1 | Proposed mechanism for vitamin D's action on the innate immune system |
| PMC2861325__F9 | An Ingenuity pathway analysis containing about half of the genes in subfactor 8 of Myc factor 6 |
| PMC2861491__F1 | Destruction of the Beta-catenin (Beta-Cat) destructor Axin |
| PMC2861543__F6 | Differential role for endocytosis in receptor-dependent Nox1 generation of ROS and activation of cellular signalling |
| PMC2861828__F1 | Signaling pathway that connects store-operated Ca2+ entry with NFAT-dependent gene transcription in T cells |
| PMC2861866__F3 | Hypothetical model linking multiple biological pathways in the development of SS-like disease based on differentially expressed genes identified in lacrimal glands by global microarray analyses |
| PMC2861953__F2 | Altered signaling pathways and mouse models of thyroid cancer |
| PMC2862089__F1 | Signal transduction pathways and crosstalk activated by insulin/IGF-1 receptor and GPCR systems |
| PMC2862093__F6 | Glucagon-like Peptide-1 Receptor (GLP-1R) is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway |
| PMC2862795__F1 | Multi-component nature of TGFB and Wnt Pathways |
| PMC2862867__F4 | Sites of action of curcumin on cancer cells |
| PMC2862880__F3 | Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer |
| PMC2863124__F1 | DNA damage and replication checkpoints in various organisms |
| PMC2863142__F1 | Posttranslational modulation of FoxO proteins is associated with intricate cellular signal transduction pathways |
| PMC2863215__F2 | Regulation of mTORC signaling networks |
| PMC2864141__F1 | Models of checkpoint control in (a) S |
| PMC2864389__F1 | PI3K/AKT signaling pathway |
| PMC2864407__F1 | Description of the sex hormone metabolic pathway: genes involved in synthesis, bioactivation, metabolism, and inactivation of estrogen and other hormones |
| PMC2864432__F3 | Insulin/IGF1 signalling pathways and AD |
| PMC2864453__F1 | Nuclear factorKB (NFKB) can be activated by a multitude of different stimuli, like TNFA, LPS and CD40L |
| PMC2864659__F6 | APE1 has dual roles in redox and DNA repair |
| PMC2864663__F4 | Aging-related upregulation of AP-1 signaling in VSMC |
| PMC2864663__F5 | Aging-related upregulation of NFKB signaling in VSMC |
| PMC2864712__F10 | PAK4 regulates adhesion and migration via multiple signalling pathways |
| PMC2864762__F13 | CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells |
| PMC2864807__F2 | PPAR Signaling Pathway and Cancer-Related Proteins in Celiac Disease-Associated Tissue Damage. |
| PMC2864813__F4a | Substance P in Polymicrobial Sepsis: Molecular Fingerprint of Lung Injury in Preprotachykinin-A-/- Mice |
| PMC2865177__F1 | ER stress-induced apoptotic pathways |
| PMC2865336__F7 | Role of Rad9A in the G2 decatenation checkpoint |
| PMC2865489__F1 | The estradiol-synthetic pathway and nuclear receptors |
| PMC2865519__F5 | A Differentiation-Based Phylogeny of Cancer Subtypes |
| PMC2865534__F1 | Heterologous Expression and Maturation of an NADP-Dependent [NiFe]-Hydrogenase: A Key Enzyme in Biofuel Production |
| PMC2865574__F3 | Wnt signaling is a complex pathway, believed to be involved in the regulation of divergent processes, including the maintenance of pluripotency and commitment to differentiation |
| PMC2866107__F5 | Current Status of Xenotransplantation and Prospects for Clinical Application |
| PMC2866141__F4 | Molecular Basis of Pulmonary Alveolar Proteinosis |
| PMC2866836__F1 | Mitochondrial Ca2+ channels/transporters and role in mitochondrial function |
| PMC2867239__F2 | The Primary Cilium as a Hedgehog Signal Transduction Machine |
| PMC2867239__F5 | The Primary Cilium as a Hedgehog Signal Transduction Machine |
| PMC2867412__F2 | Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation) |
| PMC2867902__F6 | A feed forward loop for nutritional regulation of PNPLA3 |
| PMC2867937__F12 | Segment-Specific Neuronal Subtype Specification by the Integration of Anteroposterior and Temporal Cues |
| PMC2868782__F3 | Comparison of protein and gene expression studies |
| PMC2868837__F3 | Major gene products affected by virulent infection |
| PMC2869029__F1 | Regulation of macrophage function in tumors: the multifaceted role of NFKB |
| PMC2869094__F1 | Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia |
| PMC2869339__F9 | Behavioural gene programming |
| PMC2869400__F9 | A model of Gfi-1-mediated repression of CDKN1A and other Miz-1 target genes |
| PMC2869512__F3 | Signaling pathway for zinc prevention of atherosclerosis in monocytes/macrophages and vascular endothelial cells: a proposed hypothesis |
| PMC2869518__F3 | Proximal signaling events in the TCR-coupled signaling pathway |
| PMC2869521__F1 | Role of BCR signaling to NFKB in ABC DLBCL |
| PMC2869521__F3 | Constitutive NFKB pathway activation in multiple myeloma |
| PMC2869521__F4 | Solid tumors activate the NFKB pathway to maintain cell survival |
| PMC2869556__F1 | Metabolic folate pathway |
| PMC2871322__F1 | Schematic of central regulation of body fluid regulation in response to acute changes in sodium and volume |
| PMC2871322__F3 | Schematic diagram of the forebrain neurocircuitry and peripheral inputs underlying the influences of osmotic and peripheral angiotensin II (Ang II) on sympathetic outflow and the baroreflex |
| PMC2871498__F9 | Working model for S1P/SK/S1PR interplay during acrosomal exocytosis |
| PMC2871634__F4 | WNT/Beta-catenin signaling pathway |
| PMC2871634__F5 | Regulation of apoptosis |
| PMC2871659__F1 | Overall scheme of key genetic and epigenetic events in colorectal tumorigenesis |
| PMC2871738__F2 | Molecular determinants of mitochondrial quality-control networks |
| PMC2871738__F3 | Role of the major PD-associated genes in mitochondrial dysfunction |
| PMC2871799__F6 | Human endometrial receptivity |
| PMC2871922__F4 | Regulation of spermatogenesis processes by non-classical testosterone signalling |
| PMC2872012__F4 | Functional genetic network as defined by the bioPIXIE tool (Myers et al |
| PMC2872012__F5 | Detailed representation of the interactions between the components of the gene network |
| PMC2872116__F1 | Analysis of a protein interaction network in the context of the T-cell pathway |
| PMC2872116__F2 | Structuring protein interactions around familiar canonical pathways provides intuitive visualizations |
| PMC2872188__F2 | Generalized depiction of the energy cost of neurovascular coupling and its impact on astrocytic glucose utilization (CMRglc) |
| PMC2872207__F1 | TNF-induced NFKB pathway |
| PMC2872207__F3 | Jak/STAT signaling pathway |
| PMC2872207__F4 | Akt signaling pathway |
| PMC2872497__F4 | Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment |
| PMC2872667__F3 | Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling |
| PMC2872667__F4 | Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling |
| PMC2872883__F2 | TIF scores for genes in the KEGG colorectal cancer pathway |
| PMC2872883__F3 | Small cell lung cancer |
| PMC2873055__F9 | ACBD3-mediated signaling pathway and cellular regulation |
| PMC2873061__F3a | Metabolic oxidation regulates embryonic stem cell differentiation |
| PMC2873428__F8 | Sequencing, Analysis, and Annotation of Expressed Sequence Tags for Camelus dromedarius |
| PMC2873439__F7 | CXCR5 activate PI3K isoforms through GAlpha-Src-FAK pathway or via GB/G pathway leading to subsequent activation of ERK1/2 |
| PMC2873801__F4 | Relationships between differentially expressed miRNAs, putative target genes, and functions |
| PMC2874080__F2 | Pathway of de novo synthesis of saturated and monounsaturated fatty acids and regulation of lipogenic genes by transcription factors (LXR, SREBP-1c and ChREBP) |
| PMC2874116__F2 | Intrinsic pathway is deregulated in cancer |
| PMC2874223__F1 | The figure shows one of several top-scoring multigene network associated by the Ingenuity Pathway Analysis software to seventeen genes (gray shaded symbols) of the CS2_All data set which includes both duplicated and deleted genes |
| PMC2874225__F1 | The DSBR and SDSA meiotic recombination models |
| PMC2874322__F4 | An Update on the Genetics of Atopic Dermatitis: Scratching the Surface in 2009 |
| PMC2874322__F5 | An Update on the Genetics of Atopic Dermatitis: Scratching the Surface in 2009 |
| PMC2874340__F1 | Folate cycle, methionine cycle, and transsulfuration pathway |
| PMC2874439__F3 | Schematic representing the significant changes in gene expression in the lung of Keap1ÃŽâ€2-3/ÃŽâ€2-3;CctCre+ mice compared with Keap1flox/flox mice |
| PMC2874622__F2 | The Role Of Mitochondria In The Mammalian Antiviral Defense System |
| PMC2874810__F3 | Ingenuity Pathway Analysis Network |
| PMC2875058__F2 | Several disease pathways involved in AD pathogenesis |
| PMC2875073__F5 | Albumin alters TGFB pathway gene expression |
| PMC2875112__F1a | Targeting Multiple Kinase Pathways. A Change In Paradigm |
| PMC2875223__F2 | The MSI pathway of human colon cancer |
| PMC2875624__F1 | Alterations in transforming growth factor beta signaling cause changes in chondrocyte differentiation and osteoarthritis development |
| PMC2875805__F10 | Cartoon illustrates genomic and nongenomic actions of VDR signaling in inhibition of human CYP7A1 gene transcription in human hepatocytes |
| PMC2876151__F7 | Cdk1 modulates the activity of several DNA damage checkpoint proteins |
| PMC2877394__F1 | ER and SR interactions within mammalian cells |
| PMC2877703__F1 | Anabolic and catabolic pathways regulating skeletal muscle mass |
| PMC2877959__F3 | Uric acid transport and disease |
| PMC2877979__F8 | Schematic representation of some pathways and networks modified during strain improvement program according to results obtained after proteome comparison of NRRL 1951, Wis 54-1255, and AS-P-78 strains |
| PMC2878012__F5 | Model for the role of SQSTM1 in regulating the integrity of the Keap1-Nrf2 cell defense pathway |
| PMC2878081__F7 | Schematic overview of the pyruvate/isocitrate cycle and OGC, important components of the pathway regulating glucose- and glutamine-stimulated insulin secretion |
| PMC2878746__F1 | Ret gene structure and signaling |
| PMC2878851__F1 | Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures |
| PMC2878851__F3 | Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures |
| PMC2878914__F1 | Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway |
| PMC2878924__F5 | DNA damage checkpoint pathways |
| PMC2878924__F6 | Two models for coupling the circadian clock to the cell cycle/checkpoint response |
| PMC2879143__F3 | Activation of apoptotic signaling via caspase 3 and gelsolin |
| PMC2879143__F4 | Signaling cluster and integrin signaling |
| PMC2879321__F1 | Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis |
| PMC2879563__F1 | Subdivision of the estrogen metabolic pathway |
| PMC2879972__F4 | Illustration of different mechanisms of MUC1 and MUC4 for the repression of apoptosis |
| PMC2880289__F6 | Complex deregulation of the Neuregulin/ERBB2 signaling pathway |
| PMC2880413__F2 | Networks for (A) Biological network (B) Network MDL approach (C) PMDL approach The performance on the algorithms is performed on a biological data set |
| PMC2880454__F1 | Targeting the cancer kinome through polypharmacology |
| PMC2880522__F1 | Results of a Pathway Studio® analysis of direct relationships between the components of the protein-bound fraction of renal cyst fluid |
| PMC2880683__F1 | Insulin signaling pathway |
| PMC2880865__F8 | Revitalization of a diastemal bud |
| PMC2881215__F1 | Signaling in podocyte apoptosis |
| PMC2881280__F1 | Schematic representation of the proposed enzymatic steps in the FAC -elicited JA biosynthesis pathway regulated by SIPK, WIPK and NPR1 |
| PMC2881367__F7 | CircleMap display of the ErbB2 pathway |
| PMC2881756__F7 | Model illustrating the role of WDR3 in mediating cross-talk between ribosome biogenesis and p53-mediated cell cycle regulation |
| PMC2881822__F8 | ERB Impedes Prostate Cancer EMT by Destabilizing HIF-1A and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading |
| PMC2882122__F4 | Selection of expression patterns and activities of members of the cadherin superfamily in cancer |
| PMC2882184__F1 | Pathway analysis using all altered genes and proteins |
| PMC2882188__F3 | Complement cascade |
| PMC2882232__F2 | Simplified representation of oncogenic signaling cascades in pancreatic cancer |
| PMC2882520__F3 | Disease associations in the hypothalamus (genes regulated at p<0.001; fold change > ±1.5) |
| PMC2882531__F1 | Retinoids for Treatment of Retinal Diseases |
| PMC2882734__F6 | Pathways of VLC-PUFA biosynthesis |
| PMC2882741__F1 | Schematic view of the GSL metabolism pathways |
| PMC2882796__F1 | Does Activation of the Blood Coagulation Cascade Play a Role in Malaria Pathogenesis? |
| PMC2882865__F2 | Transcriptional regulation by E2F complexes modulates cell-cycle control, cell fate, and survival |
| PMC2883240__F1 | Signaling pathways involving molecular markers for human breast cancer |
| PMC2883292__F2 | Signaling through the PI-3 Kinase-Akt pathway |
| PMC2883294__F2 | Possible mechanism of regulation of SIRT1 and AMPK pathway by CD38 inhibition |
| PMC2883337__F1 | Chromaffin cell genes involved in catecholamine biosynthesis, storage, secretion and degradation |
| PMC2883511__F1 | Signaling pathways and targets for LAM |
| PMC2883790__F2 | IGF-I activation of a signaling pathway to mTOR |
| PMC2884012__F1 | Tuberous Sclerosis Complex: A Brave New World? |
| PMC2884164__F4 | NRF2-mediated oxidative-stress response pathway that is involved with pituitary adenoma protein-mapping data |
| PMC2884164__F5 | Significant signaling pathway networks mined from pituitary adenoma comparative dataset |
| PMC2884164__F9 | ERK/MAPK signaling pathway that is involved with pituitary adenoma comparative-proteomic data |
| PMC2885083__F8 | Proposed saxitoxin biosynthetic pathway in cyanobacteria based on intermediate characterization and bioinformatic analysis |
| PMC2885101__F2 | PI3K/Akt signaling pathway |
| PMC2885424__F7 | Transcriptional Regulation of the IGF Signaling Pathway by Amino Acids and Insulin-Like Growth Factors during Myogenesis in Atlantic Salmon |
| PMC2885511__F2 | Diagram of PDGF-D cross-talks with other pathways |
| PMC2885591__F1 | With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging |
| PMC2885591__F2 | With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging |
| PMC2885703__F11 | WNT1-Inducible Signaling Pathway Protein-1 Activates Diverse Cell Survival Pathways and Blocks Doxorubicin-induced Cardiomyocyte Death |
| PMC2885761__F2 | Schematical overview of the signaling pathway mediated by MC1R |
| PMC2885902__F2 | Mitochondrial biochemical pathways that are involved in KATP-independent GSIS |
| PMC2886067__F8 | Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex |
| PMC2886068__F2 | Bile salt synthetic pathways |
| PMC2886153__F1 | Schematic representation of the intracellular cholesterol transport pathway |
| PMC2886162__F5 | SIRT1-dependent Regulation of Chromatin and Transcription: Linking NAD+ Metabolism and Signaling to the Control of Cellular Functions |
| PMC2886276__F5 | Carbohydrate metabolism and fermentation in tumor cells |
| PMC2886300__F2 | Role of ROS in TNFA induced endothelial dysfunction |
| PMC2886325__F3 | PI3K-Akt-mTOR pathway and cross-talk with other signaling cascades: (Ras/Raf/MAPK and BCR-ABL) |
| PMC2886330__F1 | Simplified diagram of the two major pathways affected by EGFR-mediated signaling in malignant glioma cells |
| PMC2886346__F10 | The pathway signaling to ERESs |
| PMC2886808__F1 | Signalling through growth factor receptors can activate the PI3K/Akt/mTOR pathway and the JAK3/STAT5 pathway |
| PMC2886982__F3 | Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes |
| PMC2887084__F1 | New Strategies in Head and Neck Cancer: epidermal growth factor receptor inhibition in head and neck cancer. |
| PMC2887259__F5 | Signaling cascades that regulate A |
| PMC2887297__F1 | Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease |
| PMC2887331__F2 | Serine/threonine kinase Akt, also known as protein kinase B (PKB), has become a major focus of attention because of its critical regulatory role in diverse cellular processes, including cancer progression |
| PMC2887678__F1 | Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells. |
| PMC2887830__F2 | Regulation of intracellular Stat3 signalling |
| PMC2888385__F6 | Nodal-Smad2 signaling regulation of the BMP pluripotency pathway in mouse ES cells |
| PMC2888472__F2 | Simplified scheme of signaling pathways required for maintenance of pluripotency of mESC (top panel) and hESC (bottom panel) |
| PMC2888474__F2 | Genetic Alterations in Glioblastoma Occur Frequently in 3 Cellular Signaling Pathways |
| PMC2888475__F1 | Cellular apoptosis pathways and intervention by both cellular anti-apoptotic proteins and viral proteins encoded by oncolytic Ad, HSV and VV |
| PMC2888582__F6 | Proteomics-Based Systems Biology Modeling of Bovine Germinal Vesicle Stage Oocyte and Cumulus Cell Interaction |
| PMC2888584__F7 | Endothelin-1 Inhibits Prolyl Hydroxylase Domain 2 to Activate Hypoxia-Inducible Factor-1A in Melanoma Cells |
| PMC2888634__F4 | Drug-induced DNA damage may be repaired by various DNA repair pathways, or apoptosis may be triggered as a result of attempted repair of platinum-induced damage by the Mismatch Repair pathway |
| PMC2888641__F1 | Targeting Hedgehog - a Cancer Stem Cell Pathway |
| PMC2889025__F1 | Response of p53 to DSBs generated by ionizing radiation |
| PMC2889025__F2 | P53 stabilization |
| PMC2889025__F4 | Crosstalk between the PI3K/AKT pathway and p53 activation: Potential stratagies for combined radiosensitization |
| PMC2889494__F3 | Protein components of the pheromone response network constructed by the PCST approach |
| PMC2889604__F7 | The regulation of neuronal migration and neurite outgrowth by the MRTF/Srf pathway |
| PMC2889681__F1 | Neurotrophic and neuroprotective pathways targeted by lithium |
| PMC2889915__F5 | Islet GPCRs and their downstream signaling pathways |
| PMC2889938__F2 | Target gene regulatory network, NFKB/RelA:P50 |
| PMC2890032__F2 | Differential vulnerability of neurons in Huntington's disease: The role of cell type-specific features |
| PMC2890409__F1 | Classification of Dengue Fever Patients Based on Gene Expression Data Using Support Vector Machines |
| PMC2890502__F2 | The yeast MAPK signalling pathways deposited in KEGG [] |
| PMC2890581__F7 | Inflammatory Mediator TAK1 Regulates Hair Follicle Morphogenesis and Anagen Induction Shown by Using Keratinocyte-Specific TAK1-Deficient Mice |
| PMC2890584__F6 | Mu-Opioid Receptors Transiently Activate the Akt-nNOS Pathway to Produce Sustained Potentiation of PKC-Mediated NMDAR-CaMKII Signaling |
| PMC2891025__F6 | Deep mRNA Sequencing for In Vivo Functional Analysis of Cardiac Transcriptional Regulators: Application to GAq |
| PMC2891151__F1 | TGFB ligands signal through the type I and type II TGFB receptors |
| PMC2891218__F7 | Possible interactions between cholinergic and eCB signaling in the toxicity of organophosphorus anticholinesterases |
| PMC2891338__F1 | Endotoxin binding: Schematic overview of the LPS, LBP, CD14 and TLR-4 signal transduction pathway |
| PMC2891586__F3 | Protein-Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks |
| PMC2891859__F1 | General overview of BDNF and GDNF signaling mechanisms |
| PMC2891887__F2 | Lymphangiogenesis and Lymphatic Metastasis in Breast Cancer. |
| PMC2891946__F7 | Crosstalks between EPCR, PAR-1, S1P1, and Tie2 |
| PMC2891948__F2 | Addicted Synapse: Mechanisms of Synaptic and Structural Plasticity in Nucleus Accumbens |
| PMC2891965__F8 | Updates in the characterization of the COX-2 pathways in human neutrophils |
| PMC2891968__F5 | Cellular pathways leading to upregulation of COX-2 in neutrophils |
| PMC2892252__F1 | Host responses to Candida albicans: Th17 cells and mucosal candidiasis |
| PMC2892298__F8 | Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors |
| PMC2892366__F10 | A model for the function of GCN2, ATF4, ASNS and Asn in conferring tumour cell protection from microenvironment stress |
| PMC2892459__F4 | Snapshots from the integrated macrophage pathway diagram |
| PMC2892459__F5 | Overlay of IfnB timecourse analysis onto the macrophage pathway using BioLayout Express3D |
| PMC2892843__F3 | Dual MAG receptor model |
| PMC2893101__F3 | Apoptosis Signalling network |
| PMC2893268__F2 | Interplays between various posttranslational modifications |
| PMC2893383__F2 | Schematic of leptin signaling through STAT3 and PDE3B pathways in POMC and NT neurons in the hypothalamus |
| PMC2893543__F4 | Schematic overview of costimulatory receptors and their ligands |
| PMC2893682__F7 | Interaction scheme of Shh and activated Beta-catenin signaling |
| PMC2894370__F4 | "Where, O Death, Is Thy Sting?" A Brief Review of Apoptosis Biology. |
| PMC2894449__F1 | Stages of apoptotic cell engulfment and associated cell signaling events that regulate each stage |
| PMC2894618__F2 | Lineage relationships of cells originating in the otocyst |
| PMC2894843__F3 | Ingenuity Pathway Assist (IPA) analysis of significant genes involved in cell death |
| PMC2894844__F7 | Schematic drawing of Akt/GSK-3B/tau signaling |
| PMC2895369__F1 | High-flux and low-flux systems of electron transfer pathways |
| PMC2895370__F1 | TLR4 signaling: The MyD88-dependent pathway through PDCD4 |
| PMC2895421__F2 | Convergent signaling pathways where inflammation and metabolic signaling intersect along the CHIEF pathway |
| PMC2895628__F5 | Mode of miRNAs that regulate adipogenesis by modulating the canonical Wnt/Beta-catenin signaling pathway |
| PMC2895650__F1 | Multi-Variant Pathway Association Analysis Reveals the Importance of Genetic Determinants of Estrogen Metabolism in Breast and Endometrial Cancer Susceptibility |
| PMC2895966__F2 | Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target |
| PMC2896553__F6 | DISTINCT SPECTRUM OF COPY NUMBER ABERRATIONS IN PAEDIATRIC HIGH GRADE GLIOMAS |
| PMC2896632__F1 | Signaling pathway of the KRAS protein |
| PMC2896660__F2 | Placing datasets into a functional context using pathway analysis |
| PMC2896712__F2 | Metabolic pathway map constructed using the E-Cell RBC model |
| PMC2896848__F2 | Alternate and peripheral androgen synthesis pathways |
| PMC2896868__F2 | Toll-like receptors in kidney disease |
| PMC2896874__F11 | Schematic overview of MAPK-regulated processes that are thought to couple light to the SCN clock during the early night |
| PMC2896911__F8 | Regulatory network that links the activities of an ensemble of transcriptional regulators, signaling components and survival factors in developing B cells into a common pathway |
| PMC2896914__F2 | Multiple genes involved in interferon production and regulation are associated with risk for lupus |
| PMC2896944__F3 | Hsp90 shelters aberrant neuronal proteins |
| PMC2896964__F1 | Schematic representation of the possible interactions between HIV-1 and the host miRNA-guided RNA silencing pathway |
| PMC2897145__F7 | Molecularly and temporally separable lineages comprise the hindbrain roof plate and contribute differentially to the choroid plexus |
| PMC2897739__F1 | Recent advances in the genetics of systemic lupus erythematosus |
| PMC2897904__F1 | Proposed mechanisms of HDACi-induced apoptosis in colon cancer cells involving the mitochondrial pathway |
| PMC2897911__F1 | Induction of Type I Interferons by Bacteria |
| PMC2897923__F1 | Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression |
| PMC2897923__F2 | Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression |
| PMC2897923__F3 | Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression |
| PMC2897958__F4 | Regulation of Lipid and Glucose Metabolism by Phosphatidylcholine Transfer Protein |
| PMC2898064__F10 | Views of predicted functional interactions |
| PMC2898064__F3 | Overlay of predicted functional interactions onto a human curated GBM pathway from the TCGA data set |
| PMC2898136__F1 | Eicosanoids and cancer |
| PMC2898136__F3 | Eicosanoids and cancer |
| PMC2898136__F6 | Eicosanoids and cancer |
| PMC2898418__F10 | Schematic pathway of IL-8-mediated NAADP formation by CD38 in LAK cells |
| PMC2898443__F1 | The eukaryotic 80 S initiation pathway |
| PMC2898451__F8 | Schematic illustration of signaling pathways involved in PDGF-mediated induction of Arc expression |
| PMC2899674__F1 | Molecular pathway for arterial, venous and lymphatic cell fate determination in vertebrate embryo |
| PMC2899872__F1 | Sequence Comparison Suggests a Role for TTL in Allantoin Biosynthesis.(A) Alignment of TTL with Urad and Urah protein from zebrafish |
| PMC2900152__F9 | Proposed DAP12 signaling pathway in macrophages and osteoclasts |
| PMC2900209__F6 | Inflammation Stages in the Acute Lung Injury in Mice. |
| PMC2900889__F8 | Possible fates of disulfide reduced SOD1 in the G93A/CCS mouse |
| PMC2901146__F2 | Taxol biosynthetic pathway |
| PMC2901320__F5 | CXCR4 pathway is affected in CD34+ cells from CAD patients |
| PMC2901551__F1 | mTOR signal pathway |
| PMC2901643__F2 | Putative signaling components in fungal mating interactions |
| PMC2901795__F1 | Left: the EGFR pathway; Right: inhibition of the EGFR pathway by the EGFR monoclonal antibodies |
| PMC2901811__F4 | II S and TOR-signaling pathway in Drosophila |
| PMC2901871__F7 | Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis |
| PMC2902124__F1 | TLR signalling |
| PMC2902148__F1 | VEGF signaling interactions |
| PMC2902148__F2 | Inhibition of VEGF signaling pathways |
| PMC2902700__F6 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE STIMULATES THE PROLIFERATION OF COLORECTAL CANCER CELLS |
| PMC2902748__F1 | Hsp90-dependent modulation of proangiogenic signaling pathways in cancer |
| PMC2902905__F1 | Sub-Cellular and Signaling Mechanisms Underlying Polar PIN Localization.A model of regulators and pathways contributing to polar PIN localization in roots is proposed based on results discussed in this review |
| PMC2903433__F4 | Chloride Regulation in the Pain Pathway |
| PMC2903563__F7 | Glucose metabolic pathway response |
| PMC2903791__F11 | Cell signaling model for the regulation of glucose metabolism in hepatocytes by taurocholate |
| PMC2903975__F1 | TLR signalling pathways: All TLRs except TLR3 share a common initial signalling pathway through MyD88 to the IRAK1/2/4TRAF6 complex |
| PMC2904042__F2 | Concurrent deregulation of the top five canonical pathways in retinoblastoma (RB) tumors |
| PMC2904169__F1 | Hypoxia-inducible factor (HIF)-2 regulates erythropoietin (EPO) |
| PMC2904682__F1 | Schematic model of regulatory pathways involved in Mycn stabilization |
| PMC2904914__F1 | Glial cell line-derived neurotrophic factor can signal through activation of Src kinases in SSCs |
| PMC2904914__F2 | Glial cell line-derived neurotrophic factor can signal through a Ras-induced pathway in SSCs |
| PMC2905036__F2 | Schematic diagram depicting the proposed role of bone morphogenetic protein (BMP) signaling pathway, HJV, HFE, and TFR2 in iron sensing and hepcidin regulation in the liver |
| PMC2905036__F3 | Schematic diagram depicting the molecular mechanisms by which inflammation activates hepcidin transcription in the liver |
| PMC2905064__F2 | Integration of oncogenic and tumor suppressor inputs by the GLI code in cancer |
| PMC2905205__F1 | Signalling routes of copper and hydrogen peroxide |
| PMC2905230__F1 | Simplified Overview of TLR Signaling |
| PMC2905316__F2 | Involvement of the Notch signaling pathway during endocrine cell differentiation |
| PMC2905406__F10 | Illustration of GDNF signaling disruption by coated silver nanoparticles |
| PMC2905467__F2 | Alternative signaling by B2-ARs |
| PMC2905627__F7 | Schematic diagram demonstrates intracellular signaling events in the Ras/ERK1/2 pathway as well as the upstream and downstream cascades activated by GDNF in the C18-4 cells |
| PMC2905744__F3 | Novel targets for the treatment and palliation of gastrointestinal neuroendocrine tumors |
| PMC2906263__F3 | Suppression of IFN-induced Jak-STAT signaling in hepatitis C |
| PMC2906469__F3 | Progressive inactivation of GSK3B may promote increased anti-apoptosis and oral cancer |
| PMC2906469__F4 | Targeting GSK3B pathway may be highly beneficial for curing oral cancer |
| PMC2907165__F1 | Type I IFN Signaling |
| PMC2907250__F1 | The three top ranked pathways in this study.'Syndecan-1-mediated signaling events' from PID; (B) 'Signaling of hepatocyte growth factor (c-Met)' from BioCarta; (C) 'Growth hormone signaling pathways' from BioCarta |
| PMC2907396__F3 | Genome-Wide Expression Profiling Deciphers Host Responses Altered during Dengue Shock Syndrome and Reveals the Role of Innate Immunity in Severe Dengue |
| PMC2907574__F4 | Inhibition of host signalling pathways by VACV members of A46 and related families |
| PMC2907698__F4 | An example of combined analysis of three identified regulatory modules |
| PMC2907713__F5 | Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways |
| PMC2907875__F8 | Estrogen and Xenoestrogens in Breast Cancer |
| PMC2908016__F2 | Therapeutic HPV vaccines |
| PMC2908393__F3 | Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy |
| PMC2908393__F4 | Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy |
| PMC2908393__F5 | Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy |
| PMC2908475__F2 | The intracellular signaling network regulating T-cell trafficking and differentiation |
| PMC2908510__F3 | Normal and Cancer-Related Functions of the p160 Steroid Receptor Coactivator (SRC) Family |
| PMC2908542__F8 | Sirtuin 3, a New Target of PGC-1A, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis |
| PMC2908610__F1 | Death receptor pathway via Fas ligand and Fas receptor |
| PMC2908618__F7 | Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomics Analysis |
| PMC2908764__F3 | Molecular cues controlling the pathway choices at the Drosophila and vertebrate midline |
| PMC2908766__F2 | PI3K dependent signal pathway |
| PMC2908768__F4 | Cytokine signaling through the Jak/Stat pathway in mammary gland development |
| PMC2909029__F2 | A possible mechanism for the inhibitory effect of p66Shc on mitogenic signaling |
| PMC2909319__F9 | Model: a Src-Tks5-Nck signalling pathway in invadopodia |
| PMC2909359__F8 | Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest |
| PMC2909379__F3 | Hox Genes and Regional Patterning of the Vertebrate Body Plan. |
| PMC2909548__F3 | Protein-protein interaction comprising the transforming growth factor B signaling pathway |
| PMC2909548__F4 | Protein-protein interaction maps comprising the transforming growth factor B signaling pathway of transcription factors associated with liver cell proliferation |
| PMC2909599__F1 | GLP-1 acts by means of the GLP-1-R to stimulate adenylyl cyclase (AC), and thereby cAMP production, and to activate the cAMP-binding proteins PKA and Epac |
| PMC2909654__F5 | Examples of human disease phenotype correlations in the absence of metabolite sharing but detected by flux correlations |
| PMC2909662__F1 | Signaling pathways of TLR4 |
| PMC2910015__F4 | General view of the species-specific regulation of histone homeostasis |
| PMC2910166__F7 | drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans |
| PMC2910227__F3 | Cellular Functions of Transient Receptor Potential channels |
| PMC2910246__F8 | Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: Apoptosis through the formation of 3-hydroxykynurenine |
| PMC2910728__F6 | Absence of Inhibin Alpha and Retinoblastoma Protein Leads to Early Sertoli Cell Dysfunction |
| PMC2910789__F1 | Selected IGF-axis genes that encode core components of IGF-axis upstream the PI3K/AKT/mTOR and RAS/MAPK/ERK pathway |
| PMC2910898__F1 | During normoxia, HIF-1A is rapidly degraded by the ubiquitin-proteasome pathway |
| PMC2911016__F1 | "Go upstream, young man": lessons learned from the p38 saga. |
| PMC2911128__F1 | PI3K/Akt/mTOR signaling pathway |
| PMC2911141__F1 | Arsenic signaling |
| PMC2911411__F3 | Network analysis of BAL proteome changes under baseline conditions |
| PMC2911442__F5 | WRN participates in the regulation of PCNA mono-ubiquitination and subsequent TLS through interaction with PCNA |
| PMC2911501__F2 | gp130-dependent cytokines promote axon regeneration and SOCS3 act as a critical negative regulator of the signaling pathway |
| PMC2911501__F3 | PTEN-regulated signaling pathway |
| PMC2912031__F4 | Reciprocal inhibition mechanism by TGFB and IFNG |
| PMC2912196__F8 | Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells |
| PMC2912204__F1 | PIK3CA and KRAS mutations predict for response to everolimus therapy: now that's RAD001 |
| PMC2912210__F1 | Targeting the mitogen-activated protein kinase pathway: physiological feedback and drug response |
| PMC2912554__F6 | Tumor suppressor pathways control Mdm2 function |
| PMC2912609__F2 | Currently available therapies targeting EGFR signaling pathway |
| PMC2912611__F8 | From HLA-B27 to spondyloarthritis: a journey through the ER |
| PMC2912657__F1 | NFKB activation pathways |
| PMC2912804__F7 | Role of PGE2 in bridging TLR4 signaling and intestinal tumorigenesis |
| PMC2912833__F3 | Generation of a biological network of genes of the most significant Canonical Pathways for the EF·CIF (Il10-/- vs |
| PMC2912833__F4 | Generation of a biological network of genes of the most significant Canonical Pathways for the Il10-/- (EF·CIF vs |
| PMC2913069__F1 | Interconnected pathways that cause bone marrow failure |
| PMC2913337__F2 | Cross talk of the Nodal/Cripto-1 signaling pathway with Wnt, hypoxia, Notch, Oct-4, and Nanog signaling pathways |
| PMC2913378__F3 | Signaling pathways that mediate actomyosin-dependent disruption of the epithelial barrier in inflammation |
| PMC2913455__F7 | E-selectin-mediated slow rolling |
| PMC2913512__F2 | G Protein-Coupled Receptor 87: a Promising Opportunity for Cancer Drug Discovery |
| PMC2913631__F3 | Schematic model of crosstalk between PPARG and Wnt-5a signaling in MSC |
| PMC2913704__F6 | TGFB1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation |
| PMC2913986__F6 | Gene Chip analysis reveal SOX11-induced regulation of Rb-E2F and TGFB signaling pathways |
| PMC2914056__F6 | Pathway packaging of the 'biopolymer metabolic process' module |
| PMC2914561__F1 | Translation control of gene expression |
| PMC2914640__F1 | Study methodology schematic |
| PMC2915454__F4 | Pathways underlying absorption of cholesterol from the intestinal lumen and its delivery to the liver |
| PMC2915629__F4 | Identification of RON-targeting genes |
| PMC2915669__F6 | Model showing the interorganellar flow of acetyl units in C |
| PMC2915700__F6 | Schematic representation of the line of events by which HA modulates the leukocyte-EC interaction |
| PMC2915738__F7 | Metalloproteinase-dependent cross-talk between the PDGFRB and the EGFR/ERK1/2 signaling pathway |
| PMC2915755__F1 | PCNA-coupled p21 degradation after DNA damage: the exception that confirms the rule? |
| PMC2915874__F3 | ER-activated postreceptor mechanisms |
| PMC2915874__F4 | Effect of estrogen on endothelium-dependent pathways of vascular relaxation |
| PMC2916219__F5 | A model for regulation pathways responsible for RN and AM symbioses |
| PMC2916406__F7 | New model for a novel role of p38 MAPK in the DNA damage response in cancer cells |
| PMC2916838__F8 | NPRL2 Sensitizes Human Non-Small Cell Lung Cancer (NSCLC) Cells to Cisplatin Treatment by Regulating Key Components in the DNA Repair Pathway |
| PMC2916958__F7 | Proposed model for the role of NOX4 and DUOX2 in promoting cell cycle entry |
| PMC2917029__F8 | Molecular pathway initiated by P4 signaling in BPBC cells |
| PMC2917144__F1 | Toll-like receptor signaling pathway |
| PMC2917385__F1 | Tumor Microenvironment in Non-Small Cell Lung Cancer |
| PMC2917731__F1 | Intracellular signaling of FIP1L1/PDGFRA+ (F/P) cells |
| PMC2917906__F1 | HIF-1A and HIF-2A have different functions in the cartilage |
| PMC2918404__F8 | Osteogenic Transcription Factor Runx2 Regulates Components of the Fibroblast Growth Factor/Proteoglycan Signaling Axis in Osteoblasts |
| PMC2918459__F1 | Biosynthetic pathway of ω3 and ω6 polyunsaturated fatty acids (PUFAs) |
| PMC2918695__F3 | HER2 signaling pathway |
| PMC2918880__F1 | Schematic depiction of selected core elements of the unfolded protein response (UPR), featuring the components measured herein (; ; ; ) |
| PMC2919048__F7 | Comparative Analysis of Extra-Embryonic Endoderm Cell Lines |
| PMC2919048__F8 | Comparative Analysis of Extra-Embryonic Endoderm Cell Lines |
| PMC2919149__F7 | Targeting HIF activation pathway for cancer therapy |
| PMC2919228__F6 | Systematic Analysis of Essential Genes Reveals New Regulators of G protein Signaling |
| PMC2919275__F2 | PD-1 Pathway in Tolerance and Autoimmunity |
| PMC2919275__F3 | PD-1 Pathway in Tolerance and Autoimmunity |
| PMC2919351__F1 | O-GlcNAc Signaling in the Cardiovascular System |
| PMC2919366__F4 | STAT3 signaling pathway |
| PMC2919370__F4 | Fanconi Anemia Proteins and Endogenous Stresses |
| PMC2919646__F2 | Cystic Kidney Disease: the Role of Wnt Signaling |
| PMC2919655__F3 | Diversity in Post-Transcriptional Control of Neutrophil Chemoattractant Cytokine Gene Expression |
| PMC2919952__F1 | Scheme of basic metabolic pathways and energy conservation in C |
| PMC2920202__F2 | Spatial-temporal signals determine the fate of activated CD8+ T cells |
| PMC2920345__F3 | Viral tricks to grid-lock the type I interferon system |
| PMC2920482__F1 | Detection of WNV and activation of IFNA/B genes and ISG according to the 2-step model |
| PMC2920636__F5 | Molecular networks over-represented by E |
| PMC2920679__F1 | Regulation of mammalian target of rapamycin (mTOR) signaling functions |
| PMC2921023__F7 | Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin |
| PMC2921074__F1 | Modulating immune function and controlling inflammation |
| PMC2921082__F1 | Adenosine monophosphate-activated protein kinase pathway in hepatic fuel metabolism |
| PMC2921082__F4 | Dual regulation of fuel metabolism and cell viability by adenosine monophosphate-activated protein kinase |
| PMC2921256__F1 | Biology of the von Hippel-Lindau/hypoxia-inducible factor (VHL-HIF) axis in the setting of hypoxia or a mutation or aberration of the VHL gene product |
| PMC2921274__F2 | Eph receptors and ephrins in cancer: bidirectional signaling and beyond |
| PMC2921274__F4 | Eph receptors and ephrins in cancer: bidirectional signaling and beyond |
| PMC2921475__F1 | Cord Blood Genomic Analysis Highlights the Role of Redox Balance |
| PMC2921576__F1 | Schematic representation of hepatic methionine metabolism |
| PMC2921605__F1 | PIK3/Akt/mTOR Pathway |
| PMC2921612__F1 | Molecular Diagnosis and Therapy of Kidney Cancer |
| PMC2921957__F4 | Summary of factor H recognition functions and interactions |
| PMC2921989__F1 | Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein |
| PMC2921989__F2 | Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein |
| PMC2922045__F1 | TLR AGONISTS: Are They Good Adjuvants? |
| PMC2922222__F1 | Conserved ATR→CHK1 checkpoint signaling pathway in eukaryotes (, ) |
| PMC2922475__F1 | CD73: A novel target for cancer immunotherapy |
| PMC2922498__F2 | Schematic for DSB repair by HR and NHEJ pathways |
| PMC2922518__F1 | Schematic illustration depicting the cellular pathways that lead to eIF4E activation and phosphorylation by Mnk1/2 |
| PMC2922838__F2 | Gene expression profiling in whole blood of patients with coronary artery disease |
| PMC2923187__F8 | Hybrid Models Identified a 12-Gene Signature for Lung Cancer Prognosis and Chemoresponse Prediction |
| PMC2923204__F2 | Post-synaptic BDNF-TrkB Signaling in Synapse Maturation, Plasticity and Disease |
| PMC2923369__F2 | Auto-layout of 'Caffeine (C) neighborhood' based on Ingenuity curated finding (IPA, Ingenuity® Systems) |
| PMC2923430__F9 | Immune Response |
| PMC2923453__F1 | Molecular Pathways: Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma |
| PMC2923715__F5 | Wnt signaling pathways |
| PMC2923738__F4 | Human erythrocyte metabolism modeled using detailed enzyme rate equations |
| PMC2923753__F2 | Signalling pathways that regulate Candida albicansCHS gene expression |
| PMC2923990__F7 | Model for C |
| PMC2924379__F2 | Examination of Apoptosis Signaling in Pancreatic Cancer by Computational Signal Transduction Analysis |
| PMC2924553__F1 | BMP signal transduction |
| PMC2924648__F3 | Directed cell migration |
| PMC2924816__F1 | Quantification of Beta-Catenin Signaling Components in Colon Cancer Cell Lines, Tissue Sections, and Microdissected Tumor Cells using Reaction Monitoring Mass Spectrometry |
| PMC2924908__F2 | Complement - a key system for immune surveillance and homeostasis |
| PMC2924916__F2 | P-values for testing association of the genes within the MAPK signaling pathway with RA in WTCCC studies |
| PMC2924916__F3 | P-values for testing association of the genes within the MAPK signaling pathway with RA in NARAC studies |
| PMC2925029__F3 | The IFN-λ receptor signaling pathway |
| PMC2925066__F1 | Major Apoptotic pathways |
| PMC2925528__F1 | Summary of the systemic involvement of choline-containing species and their potential relationship with inflammatory processes |
| PMC2926258__F3 | Schematic representation of the role of T cells in the mechanism by which intermittent PTH treatment stimulates bone formation |
| PMC2926749__F4 | Proposed model for MALT1 function in NFKB activation |
| PMC2926929__F1 | The Effects of EPA, DHA, and Aspirin Ingestion on Plasma Lysophospholipids and Autotaxin |
| PMC2926984__F1 | The cholesterol and triglyceride-phospholipid biosynthesis pathways |
| PMC2926987__F3 | Reconstructed antioxidant regulation pathway of detoxifying proteins |
| PMC2927346__F1 | Irinotecan pharmacogenomics |
| PMC2927527__F2 | "Mens Sana In Corpore Sano": Exercise and Hypothalamic ER Stress |
| PMC2927928__F3 | Molecular pathways involved in pancreas and liver differentiation from hES cells |
| PMC2927952__F3 | Insulin signaling pathway from PathVisio |
| PMC2928145__F1 | Lung cancer in women: role of estrogens |
| PMC2928307__F1 | Plastids play a central role in the generation of wounding and herbivory induced signals |
| PMC2928401__F8 | Identification of Primary Gene Targets of TFAP2C in Hormone Responsive Breast Carcinoma Cells |
| PMC2928541__F2 | Wnt signaling pathway |
| PMC2928642__F8 | The PA-mediated activation of mTORC1 signaling |
| PMC2928685__F1 | Schematic diagram of the interaction of HH signalling on p53 and Nanog |
| PMC2928709__F4 | Observation of the differentially expressed genes on the human cell cycle (A) and transforming growth factor beta (TGFB) signaling pathways (B) modified from Kyoto Encyclopedia of Genes and Genomes (KEGG) (www.genome.jp/kegg/kegg1.html) |
| PMC2928711__F9 | Leptin upregulates VEGF in breast cancer via canonic and non-canonical signaling pathways and NFKB/HIF-1A activation |
| PMC2928803__F3 | Gene Expression Model for the Preferential Galactose Uptake in Yeast Cells |
| PMC2928959__F6 | Hypothetical model for EGFR-dependent loss of cell polarity and activation of Wnt signaling in CS-exposed human airway epithelium |
| PMC2929006__F5 | Genetic basis of kidney cancer: a metabolic disease |
| PMC2929244__F6 | Defects in physiologically driven actin signaling at hippocampal synapses in Fmr1-KO mice |
| PMC2929310__F3 | Transcript abundance patterns in Kawasaki disease patients with IVIG resistance |
| PMC2929310__F6 | Transcript abundance patterns in Kawasaki disease patients with IVIG resistance |
| PMC2929604__F1 | Role of TLR4 in hepatic I/R injury |
| PMC2929667__F6 | Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation |
| PMC2929731__F8 | cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways |
| PMC2929918__F1 | Homocysteine metabolism in the liver |
| PMC2929951__F8 | Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome |
| PMC2930200__F1 | Molecular machinery of myelin gene transcription in Schwann cells |
| PMC2930269__F2 | CSCs drug resistance methodology |
| PMC2930641__F2 | MAPK Signaling Pathway |
| PMC2930664__F1 | One-Carbon Metabolism and Alzheimer's Disease: Focus on Epigenetics |
| PMC2930670__F2 | Iron redox cycling in aerobic iron metabolism |
| PMC2930673__F1 | Cellular iron processing |
| PMC2930673__F2 | Transport of heme synthesis intermediates and heme in metazoans |
| PMC2930805__F1 | Metabolic signaling pathway of candidate pathway |
| PMC2930807__F4 | Gene pathway analysis |
| PMC2930854__F10 | Ephrin-A5 and EphA5 Interaction Induces Synaptogenesis during Early Hippocampal Development |
| PMC2931413__F1 | Hermaphroditism in Caenorhabditis nematodes.(A) The Caenorhabditis hermaphrodite gonad |
| PMC2932466__F3 | Signal transduction mechanisms involved in the mediation of cellular responses induced by secreted MIC-1 cytokine in certain cancer cells |
| PMC2932530__F9 | Redox regulation of the PI3K/Akt signaling pathway |
| PMC2932677__F1 | Diversity and Plasticity of Th Cell Types Predicted from Regulatory Network Modelling |
| PMC2932783__F1 | Targeting of signaling pathways by arsenic trioxide in chronic lymphocytic leukemia cells |
| PMC2933174__F6 | Model depicting a novel mechanism by which cetuximab induces autophagy |
| PMC2933206__F7 | Hypothetical model of how Str1 may affect cellular behavior via the Beta-catenin/LEF signal transduction pathway |
| PMC2933224__F1 | Gradient Descent Optimization in Gene Regulatory Pathways |
| PMC2933224__F3 | Gradient Descent Optimization in Gene Regulatory Pathways. |
| PMC2933224__F4 | Gradient Descent Optimization in Gene Regulatory Pathways |
| PMC2933229__F3 | The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas |
| PMC2933269__F1 | Activin signaling regulates transcription of the FSHB gene |
| PMC2933389__F9 | Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications. |
| PMC2933544__F3 | Proposed model of epidermal growth factor receptor (EGFR) aberrant activation and trafficking in the setting of cigarette smoke (CS) |
| PMC2933570__F1 | Coordinated upregulation of cytoprotective genes occurs as a result of Nrf2 activation |
| PMC2933652__F4 | Implications of PC12 cell microarray/transcriptome analysis for pituitary adenylate cyclase-activating polypeptide (PACAP) actions, and PACAP-activated signaling pathways, in vivo |
| PMC2933676__F3 | The canonical Wnt signaling pathway |
| PMC2933688__F3 | EGFR signaling and NHEJ |
| PMC2933845__F4 | Genistein inhibits critical pathways in cancer invasion |
| PMC2933905__F2 | Distinct functions for TPPII in the nucleus and cytosol |
| PMC2934757__F1a | Defining the pathway to insulin-like growth factor system targeting in cancer |
| PMC2934775__F8 | Fluxmap of the glycolysis, penthose phosphate pathway, and citric acid cycle for the experiment where carbon-limiting medium is changed to nitrogen-limiting medium at time zero |
| PMC2934775__F9 | Fluxmap of the glycolysis, penthose phosphate pathway, and citric acid cycle for the experiment where nitrogen-limiting medium is changed to carbon-limiting medium at time zero |
| PMC2934865__F2 | Hypothetical model for SUMO regulation in NFKB pathway |
| PMC2935201__F3 | Platelets, Petechiae, and Preservation of the Vascular Wall |
| PMC2935335__F1 | The highly simplified PI3K/Akt and MAP kinase pathways in thyroid cancer |
| PMC2935989__F2 | GRK2 interactome involved in cell migration |
| PMC2935989__F3 | GRK2 interactome involved in the modulation of cell cycle progression |
| PMC2936065__F2 | The Lrp5-dependent regulation of bone formation through inhibition of tph1 expression and 5-HT synthesis in enterochromaffin cells |
| PMC2936296__F2 | RIG-I signalling pathway |
| PMC2936527__F1 | Synthesizing and Salvaging NAD+: Lessons Learned from Chlamydomonas reinhardtii |
| PMC2936760__F5 | Signaling pathways described in ARPE19 cells |
| PMC2937064__F1 | Leptin, IGFBP3, and rapamycin suppress the IGF-1 signaling pathway to preserve naïve T cells and promote longevity |
| PMC2937064__F3 | CD28 signaling pathway in T cells is equivalent to the IGF-1 pathway in the whole organism |
| PMC2937064__F4 | Reactive oxygen species, UV light or other genotoxic stresses, that induce DNA damage, principally, double-stranded breaks, is detected by the MRE11-RAD50-NBS1 complex, which in turn activates ATM |
| PMC2937358__F1 | ERAlpha-Negative and Triple Negative Breast Cancer: Molecular Features and Potential Therapeutic Approaches |
| PMC2937452__F1 | Model of pyrimidine synthesis and salvage pathways in Toxoplasma gondii |
| PMC2937518__F4 | Overview of predicted carbohydrate uptake and metabolism systems in bifidobacteria |
| PMC2937585__F1 | Folate metabolic pathway |
| PMC2938013__F9 | Dixdc1 is a critical regulator of DISC1 and embryonic cortical development |
| PMC2938097__F6 | TNF/Fas/TRAIL signaling pathway |
| PMC2938100__F4 | Connections of literature-completed interactome of PI3K-mTOR pathway with other signaling pathways |
| PMC2938150__F3 | Comparison of fluxes of central carbon metabolism determined by MFA and predicted from a genome-scale metabolic model |
| PMC2938197__F1 | Predicted hydroxy/hydroperoxy wybutosine biosynthesis pathway and domain architecture of key enzymes involved in its synthesis |
| PMC2938570__F2 | mTOR-independent pathway, with multiple drug targets acting at various places in this pathway that induce autophagy |
| PMC2938637__F2 | Current model of early symbiotic signaling pathways |
| PMC2938833__F2 | Actin-cytoskeleton signaling pathway and the candidate genes involved in colorectal cancer progression in patients with ulcerative colitis |
| PMC2938833__F3 | Pfn gene neighborhood and its interacting pathway |
| PMC2939005__F1 | Two major insulin signaling pathways |
| PMC2939232__F10 | Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2) |
| PMC2939266__F3 | Dopamine-sensitive signaling via adenylyl cyclase (AC), phospholipase C (PLC), and phosphatidylinositol-3-kinase (PI3K) systems |
| PMC2939298__F1 | Schematic diagram of androgen biosynthesis |
| PMC2939308__F1 | Activation of PPARG and PTEN Cascade Participates in Lovastatin-mediated Accelerated Differentiation of Oligodendrocyte Progenitor Cells |
| PMC2939362__F1 | Domain organization of proteins in the Hh signaling pathway |
| PMC2939392__F2 | Proposed inhibitory mechanisms of SOCS1 on TLR signaling |
| PMC2939393__F1 | The Fe-S biogenesis proteins, ISCA and C1orf69 (Iba57 homologue), may impact heme synthesis by affecting the production of succinyl-CoA, a substrate of heme synthesis |
| PMC2939609__F3 | Molecular interactomes and sub-networks associated with tumor cell susceptibility to arsenic trioxide |
| PMC2939633__F1 | Chk1 suppressed death pathways |
| PMC2939656__F4 | Complement/Coagulation pathway activation |
| PMC2939720__F1 | Viral hijacking of the host ubiquitin system to evade interferon responses |
| PMC2940266__F1 | Phosphatase and Tensin Homologue deleted on Chromosome 10: Extending its PTENtacles |
| PMC2940266__F2 | Phosphatase and Tensin Homologue deleted on Chromosome 10: Extending its PTENtacles |
| PMC2940478__F3 | Web-accessible GnRHR pathway navigator |
| PMC2940738__F7 | ETS-4 Is a Transcriptional Regulator of Life Span in Caenorhabditis elegans |
| PMC2940871__F3 | Metabolic reactions involving the PGM2 (adapted from []) |
| PMC2940983__F1 | Histone GH2AX and Poly(ADP ribose) as Clinical Pharmacodynamic Biomarkers |
| PMC2941735__F2 | Targeting Non-Homologous End-Joining Through Epidermal Growth Factor Receptor Inhibition: Rationale and Strategies for Radiosensitization |
| PMC2942073__F1 | Genetics of Psychosis in Alzheimer Disease: A Review |
| PMC2943133__F2 | Toll-like receptor (TLR) signalling is mediated by at least two distinct pathways |
| PMC2943291__F6 | Proposed scheme of the molecular mechanism underlying LPCAT2 activation |
| PMC2943318__F7 | Ulk3 function in Shh signaling pathway |
| PMC2943423__F1 | Advances and challenges in malaria vaccine development |
| PMC2943488__F1 | Schematic of the drug- and cytokine-induced hepatocellular death signaling network, curated from literature references-, - |
| PMC2943518__F7 | Diagram of a putative LPS-induced PTP/LITAF/TNF signaling pathway |
| PMC2943748__F6 | SENP1 participates in the dynamic regulation of Elk-1 SUMOylation |
| PMC2943859__F5 | Death receptor signaling and its interdigitation with the mitochondrial pathway of apoptosis |
| PMC2943859__F9 | TNF-R1 signaling pathways |
| PMC2943975__F1 | TOR signaling never gets old: Aging, longevity and TORC1 activity |
| PMC2944186__F1 | Convergence between Wnt and EGFR pathways |
| PMC2944409__F6 | Calcium Signaling Pathway (KEGG, Kanehisa Laboratory in Kyoto University, Japan) with vinclozolin altered genes indicated |
| PMC2944409__F7 | Gene interaction sub-network of shortest connections to common targets for the 36 candidate regulatory genes obtained by global literature analysis (Pathway Studio 7.0, Ariadne Genomics Inc., Rockville MD) |
| PMC2944809__F5 | Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence |
| PMC2944875__F2 | Gene Expression Study of Monocytes/Macrophages during Early Foreign Body Reaction and Identification of Potential Precursors of Myofibroblasts |
| PMC2945029__F6 | Pathways and networks related to chondrocyte proteins identified by proteomics as altered by GS and/or CS |
| PMC2945208__F1 | KEEPING AN EYE ON RETINOBLASTOMA CONTROL OF HUMAN EMBRYONIC STEM CELLS |
| PMC2945208__F3 | KEEPING AN EYE ON RETINOBLASTOMA CONTROL OF HUMAN EMBRYONIC STEM CELLS |
| PMC2945394__F1 | Post-pandrial increase in insulin leads to induction of lipogenesis and inhibition of lipolysis |
| PMC2945462__F1 | Complement cascade is comprised of the Classical, Alternative, and Mannose Binding Lectin pathways |
| PMC2945552__F11 | Proposed signaling pathway modulated by TH2-3 in LPS-induced RAW264.7 cells |
| PMC2945562__F8 | Summary of signaling pathways for cPLA2A activation and eicosanoid production stimulated by engagement of C |
| PMC2945668__F1 | TLR7/9 Signaling pathway leading to the production of proinflammatory cytokines and type I IFN |
| PMC2945688__F1 | Deletion of the NAD+ de novo pathway genes, nadABC, in M |
| PMC2945784__F2 | Cancer signaling pathways affected within the tumor |
| PMC2945811__F1 | FA-regulated ICL repair |
| PMC2945950__F1 | BCR signaling pathway |
| PMC2945950__F2 | ERBB signaling pathway |
| PMC2945950__F5 | Moral graph Dm obtained from BCR pathway |
| PMC2945950__F6 | Triangulated graph Dt obtained from BCR pathway |
| PMC2946515__F3 | Mutant epidermal growth factor receptor, EGFRvIII, promotes cell survival and proliferation by preferential signaling through the phosphotidyinositol-3-kinase (PI3K) pathway |
| PMC2946555__F2 | Merlin, a "Magic" Linker Between the Extracellular Cues and Intracellular Signaling Pathways that Regulate Cell Motility, Proliferation, and Survival. |
| PMC2946881__F1 | Regulation of adipogenesis by canonical Wnt signaling cascade |
| PMC2947178__F8 | Model for the Coordinated Action of the Mating Types to Regulate Different Stages of Pathogenic Development of U |
| PMC2947220__F8 | Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer |
| PMC2947266__F10 | The signaling transduction pathway leading to tPA induced fibroblast proliferation |
| PMC2947752__F7 | The role of PDGF signaling in the PrE lineage of the mouse blastocyst |
| PMC2947794__F1 | Examination of Association to Autism of Common Genetic Variation in Genes Related to Dopamine |
| PMC2947835__F2 | Membrane proximal intracellular signals at the IS versus the HIV VS |
| PMC2947987__F3 | Genome of a Pathogenic Rhodococcus: Cooptive Virulence Underpinned by Key Gene Acquisitions |
| PMC2948187__F1 | Altered cellular pathways and processes in tumours |
| PMC2948275__F1 | Putative functions of caspase-2 |
| PMC2948292__F1 | Potential roles of BLM and RECQ5 in sister chromatid exchange regulation |
| PMC2948329__F2 | TSC1/2 integrates multiple signals to control cell growth and proliferation |
| PMC2948497__F6 | cDNA Microarray Gene Expression Profiling of Hedgehog Signaling Pathway Inhibition in Human Colon Cancer Cells |
| PMC2948541__F5 | Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders |
| PMC2948618__F3 | 3rd US-EU Workshop Systems level understanding of DNA damage responses |
| PMC2948663__F1 | Molecular and genetic events in mammalian sex determination and differentiation |
| PMC2949025__F2 | Correlations (Spearman) of biomass growth (biom) and lignin levels with transcript abundance of specific monolignol biosynthetic genes in a interspecific pseudo-backcross pedigree of Populus (family 52-124) |
| PMC2949081__F1 | Summary of the RAS incorporating the Ang peptide family and physiological effects mediated via ATR subtypes |
| PMC2949087__F5 | Mitochondria and neuroplasticity |
| PMC2949127__F3 | HMGB1 signaling events mediated by RAGE and TLR2/4 and therapeutic strategies for cerebral ischemia |
| PMC2949129__F7 | Putative signaling pathways leading to translational activation and enhanced MCT2 protein synthesis after BDNF treatment in cultured cortical neurons |
| PMC2949191__F6 | Scheme outlining the novel role of Nogo-A in controlling neuronal survival in the ischemic brain |
| PMC2949386__F6 | Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity |
| PMC2949446__F1 | Luteolin and gefitinib regulation of EGF Signaling Pathway and Cell Cycle Pathway genes in PC-3 human prostate cancer cells |
| PMC2949481__F2 | Insulin, IGF-I and IGF-II signaling through the IGF-IR |
| PMC2949529__F1 | O-GlcNAc Signaling: A Metabolic Link Between Diabetes and Cancer? |
| PMC2949529__F2 | O-GlcNAc Signaling: A Metabolic Link Between Diabetes and Cancer? |
| PMC2949647__F1 | Structure and signaling machinery of the Met receptor |
| PMC2949659__F1 | Tamoxifen metabolic pathway |
| PMC2949723__F3 | Eicosanoid signaling pathway from Ingenuity Pathway Analysis software |
| PMC2949777__F5 | JAK/STAT pathway in infected EPCs |
| PMC2949778__F1 | Folate metabolic pathway |
| PMC2949900__F4 | Cell Cycle Pathway: Differentially expressed genes involved in the cell cycle are shown in pink |
| PMC2950025__F1 | Models of mitotic exit in yeast |
| PMC2950451__F3 | Metabolic flux distribution through branching areas of the central metabolism of MG1655 and ECOM4LA cell lines |
| PMC2950652__F2 | Pioneer Round of Translation: Features and Functions |
| PMC2950751__F9 | Summary schematic illustrating the adaptations of select genes of the IGF-1/PI3K/Akt pathway involved in protein synthesis and degradation analyzed in the plantaris muscle |
| PMC2951022__F1 | Toll-like receptor (TLR) signaling pathways |
| PMC2951227__F7 | Hypothetical model for Rad18-dependent activation of the FA pathway in response to bulky DNA adducts |
| PMC2951628__F1 | Inflammation Joins the "Niche" |
| PMC2951839__F1 | Lower Succinyl-CoA:3-ketoacid-CoA Transferase (SCOT) and ATP Citrate Lyase In Pancreatic Islets of A Rat Model of Type 2 Diabetes: Knockdown of SCOT Inhibits Insulin Release In Rat Insulinoma Cells |
| PMC2952128__F4 | Functional gene networks identified using IPA from differentially expressed genes between control and 300 nM reversine-treated annulus fibrosus cells |
| PMC2952191__F2 | mTOR signaling pathway |
| PMC2952341__F1 | Alteration of Notch signaling in skeletal development and disease |
| PMC2952389__F1 | Outline of T-cell development pathway from bone marrow to the thymus |
| PMC2952492__F1 | Regulation of neo-vascularization by SDF-1 |
| PMC2952500__F1 | Schematic diagram showing the results of ras activation by Grb2 |
| PMC2952980__F1 | Multifactorial pathway leading to gastric carcinoma |
| PMC2953155__F5 | Model schematic of Nipah virus-triggered DC immune response mechanisms and antagonist activity of the response |
| PMC2953417__F1 | REGULATION OF NITRIC OXIDE PRODUCTION IN HEALTH AND DISEASE |
| PMC2953449__F3 | Different effects of gut- and brain-derived serotonin on the osteoblast |
| PMC2953497__F10 | Tumor Necrosis FactorA Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells |
| PMC2953497__F9 | Tumor Necrosis FactorA Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells |
| PMC2953617__F2 | JS genes implicated in the Shh, Wnt, and PDGFA signaling pathway |
| PMC2953915__F7 | Model of E2F2-mediated regulation of the Ahr pathway |
| PMC2954189__F1 | Simplified scheme of the double-edged role of Akt in tumor development |
| PMC2954288__F10 | Hypothetical model for SWAP-70 function in mast cell FcERI signaling |
| PMC2954312__F2 | Crosstalk between the three distinct oscillators that function in the mouse PSM.(a) Schematic diagram of a signalling and a responding cell in the mouse PSM, detailing cyclic genes of the Notch, Fgf and Wnt pathways |
| PMC2954716__F4 | Developmental Programming: Differential Effects of Prenatal Testosterone Excess on Insulin Target Tissues. |
| PMC2954727__F1 | Working model of the effects of E2 on cell migration |
| PMC2954851__F2 | Protein serine/threonine phosphatases in the DNA damage response pathway |
| PMC2955136__F3 | Highly expressed proteins in MII oocytes |
| PMC2955136__F4 | Highly expressed proteins in zygotes |
| PMC2955448__F1 | Pathogenesis of prostate cancer: from molecular to metabolic alterations |
| PMC2955614__F5 | Novel molecular regulation of Wnt/Beta-catenin pathway |
| PMC2955618__F6 | Runx2-regulated cancer-related gene network |
| PMC2955764__F1 | Sonic hedgehog signaling pathway |
| PMC2955882__F4 | ENaC and ASL volume regulation |
| PMC2955921__F2 | Scheme summarizing the differential effect of PARP-1 inhibition versus silencing on SSB repair via the BER pathway |
| PMC2955993__F1 | Complement and Periodontitis |
| PMC2955993__F3 | Complement and Periodontitis |
| PMC2955995__F1 | Targeting Notch signaling pathway to overcome drug-resistance for cancer therapy |
| PMC2956014__F2 | Neutrophil apoptosis |
| PMC2956082__F6 | Simple diagram of FTY720 action in the mitochondria mediated apoptotic pathway |
| PMC2956119__F1 | This figure shows the two distinct but ultimately converging apoptosis signaling pathways in mammals |
| PMC2956119__F2 | The many roles of FAS receptor signaling in the immune system. |
| PMC2956119__F3 | The many roles of FAS receptor signaling in the immune system. |
| PMC2956132__F1 | Catecholamine biosynthetic pathway |
| PMC2956378__F7 | Thrombin-induced ET-1 secretion in RPE is rho/ROCK1/2 dependent |
| PMC2956608__F1 | Inhibition of the type I interferon (IFN) pathway of Kaposi's sarcoma-associated herpesvirus (KSHV) |
| PMC2956794__F1 | Targeting DNA repair proteins for cancer treatment |
| PMC2956880__F4 | Schematic diagram showing the interaction of the p75NTR and TrkB signaling pathways |
| PMC2957472__F3 | Helicobacter pylori: gastric cancer and beyond |
| PMC2957678__F1 | Schematic view of HMGB1 signal transduction |
| PMC2957845__F6 | Scheme of the Wnt signalling pathway including proteins from the RT-PCR array |
| PMC2957893__F3 | Genes in one pathway have complex "net" interactions, which should be taken into consideration when analyzing proteomics/genomic data |
| PMC2958130__F5 | Intertwining Threshold Settings, Biological Data and Database Knowledge to Optimize the Selection of Differentially Expressed Genes from Microarray |
| PMC2958210__F12 | Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice |
| PMC2958213__F1 | The Neuregulin Signaling Pathway and Schizophrenia: From Genes to Synapses and Neural Circuits |
| PMC2958230__F1 | Effect of TBCD and its Regulatory Interactor Arl2 on Tubulin and Microtubule Integrity |
| PMC2958340__F3 | Canonical Wnt/Beta-catenin signaling |
| PMC2958833__F2 | Nutritional Programming in the Rat Is Linked to Long-Lasting Changes in Nutrient Sensing and Energy Homeostasis in the Hypothalamus |
| PMC2958907__F1 | Web-accessible DC pathway navigator |
| PMC2959043__F3 | Wnt/Beta-catenin signaling Ctenophore pathway |
| PMC2959101__F4 | Schematic diagram of NELL-1 signaling pathways in osteoblast cells |
| PMC2962793__F1 | a, b Bioactive eicosanoids derived from the arachidonic acid cascade |
| PMC2962793__F2 | Cytochrome P450 epoxygenase expression in tumor cell compartments and their potential role in cell-cell communication in the tumor stroma |
| PMC2962956__F1 | Toll-like receptor (TLR) signalling and inhibition by viral proteins |
| PMC2963059__F1 | Canonical Wnt/Beta-catenin pathway |
| PMC2963059__F2 | Non-canonical Wnt pathways |
| PMC2963103__F1 | Normal biology of the VHL-HIF axis in the setting of (A) normoxia and (B) hypoxia |
| PMC2963106__F2 | VHL in clear-cell renal cell carcinoma and its relation to targeted therapy |
| PMC2963118__F2 | HRS cell and its cellular microenvironment |
| PMC2963142__F1 | TLR signaling pathway and downstream effector molecules |
| PMC2963177__F2 | Integration of non-SMAD and SMAD signaling in TGFB1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells |
| PMC2963391__F6 | PGC-1A coordinates anabolic and catabolic pathways in skeletal muscle |
| PMC2964046__F1 | Currently-known relationships among genes analyzed based on manually curated examination of the published literature within the Ingenuity Pathway Analysis® Knowledge Base |
| PMC2964117__F2 | Small-molecule inhibition of the parasite nicotinate mononucleotide adenylyltransferase (NMNAT) |
| PMC2964177__F1 | ErbB2 cellular signaling pathways and lapatinib mechanism of action |
| PMC2964746__F4 | Selected signal transduction pathways that affect AS of transcripts of genes important in cancer |
| PMC2964873__F1 | The Siah2-HIF-FoxA2 axis in prostate cancer - new markers and therapeutic opportunities |
| PMC2964899__F1 | Schematic representation of the molecular events associated with cellular processing, lipid modification, and secretion of the SHH protein and the autocrine and paracrine actions of mature and secreted SHH protein |
| PMC2964899__F3 | Molecular events associated with the repressive effect induced by PTCH1 receptor on the SMO activity and the activation of the Hh signaling pathway mediated by the SHH protein in the primary cilium |
| PMC2964899__F5 | Cellular events and signaling elements involved in the regulation of SHH expression, GLI activation, and mediation of the Hh activation-induced cellular response |
| PMC2964899__F6 | Scheme showing the signaling elements and frequent deregulations in the Hh signaling network and potential cross-talk with the EGFR signaling pathway involved in the malignant behavior of cancer cells |
| PMC2964935__F5 | PAR Proteins: Fundamental Players in Animal Cell Polarization |
| PMC2964976__F8 | CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs |
| PMC2965188__F2 | Nrf2 cytoprotective signaling pathway |
| PMC2965566__F2 | Transcriptional control of invariant NKT cell development |
| PMC2965861__F1 | The AMPK pathway in relation to various molecules |
| PMC2966065__F1 | Chemical structure of OHyW in tRNAPhe and its biosynthetic pathway |
| PMC2966096__F7 | A hypothetical model of PAR-1 and PAR-2 activation by coagulation proteases when either EPCR or an unknown FX/FXa receptor is occupied by natural ligands |
| PMC2966110__F8 | Stbd1 participation in glycogen metabolism and Stbd1 structure |
| PMC2966480__F2 | Regulation of xenobiotic metabolism by AhR and NRF2 |
| PMC2966480__F4 | E3 ubiquitin ligase activities of KEAP1 and AHR |
| PMC2966480__F5 | Repression of NRF2 signaling by members of the NFKB pathway |
| PMC2966484__F3 | Activation of the NFKB signaling pathway |
| PMC2966547__F1 | Homocysteine metabolic pathways |
| PMC2966895__F2 | Complement-targeted therapeutics |
| PMC2966904__F7 | Proposed scheme of the signaling pathway by TfR2 and HFE |
| PMC2966944__F8 | Cartoon summary of expression and anatomical data, and a model for phases of A/P axis re-organization |
| PMC2967529__F8 | Model for vertebrate limb induction and outgrowth |
| PMC2967585__F9 | Mechanisms involved in alcohol-mediated suppression of type I IFN pathway in human hepatocytes |
| PMC2967651__F1 | A model for interplay between alloimmunity and autoreactivity in graft rejection |
| PMC2970576__F5 | Analysis of gene expression in CD44+/CD24- MCF-7/ADR cell population by TaqMan Low-Density Array and Ingenuity Pathway analysis |
| PMC2970638__F8 | Up-regulation of Paxillin and Focal Adhesion Signaling follows Dystroglycan Complex deletions and promotes a Hypertensive State of Differentiation |
| PMC2970711__F7 | Scheme of cross-talk interactions between TIM-3, Gal-9 and TLR4 signaling networks |
| PMC2971463__F3 | SLIT/ROBO pathway: a regulator of cell function with implications for the reproductive system |
| PMC2971525__F1 | DNA Damage Response (DDR) pathways in normal and malignant cells |
| PMC2971717__F1 | Schema of the HER family signaling pathways |
| PMC2972203__F8 | Reverse-Phase Phosphoproteome Analysis of Signaling Pathways Induced by Rift Valley Fever Virus in Human Small Airway Epithelial Cells |
| PMC2972271__F5 | The metabolite NAD+ oscillates in a circadian manner |
| PMC2972642__F2 | REVIEW: Oxytocin: Crossing the Bridge between Basic Science and Pharmacotherapy. |
| PMC2972700__F1 | Wnt Signaling During Fracture Repair |
| PMC2972986__F1 | Biological processes known to be stimulated in an AHR-dependent and/or AHR-independent manner by the tryptophan photoproduct FICZ |
| PMC2974067__F1 | Signaling pathways that regulate longevity in C |
| PMC2974170__F1 | Diagram of TLR signaling pathways |
| PMC2974212__F3 | Critical growth factors and signalling pathways controlling human trophoblast invasion |
| PMC2974215__F2 | TNF-dependent signalling pathways mediated through TNFR1 and TNFR2 |
| PMC2974775__F4 | Ca2+ waves activate transcription factor NFAT that in turn controls cell cycle |
| PMC2974943__F2 | Intracellular signaling pathway within cranial neural crest cells mediated by endothelin-1 (Edn1) |
| PMC2975074__F3 | Cell stress response: activation of the aggresome pathway, HSPs, and transcriptional response |
| PMC2975092__F6 | Biological interaction between glucose and genes up- (light grey) or down-regulated (white) in primary hepatic stellate cells after overexpression of Smad7 |
| PMC2975149__F6 | Models of the regulation of prenylation and trafficking of PBR-containing small GTPases by SmgGDS splice variants |
| PMC2975200__F9 | MyD88-induced protein accumulation pathways through SQSTM1 and HDAC6 |
| PMC2975271__F9 | Schematic model for regulation of mTOR pathway signaling through interaction of the p53 target Plk2 with TSC proteins |
| PMC2975490__F1 | Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis |
| PMC2975924__F3 | Eph/ephrin signaling regulates intestinal cell positioning and proliferation |
| PMC2975936__F1 | Classical pathway of complement activation by antibody |
| PMC2975941__F2 | Classical and non-canonical NFKB pathways |
| PMC2975945__F2 | Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS |
| PMC2975945__F4 | Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS |
| PMC2976306__F7 | Changes in gene expression in central carbon metabolism (A) and ergosterol synthesis (B) |
| PMC2976339__F5 | Gene expression within cluster MCL2 is enriched in genes affecting NK cell-mediated cytotoxicity |
| PMC2976847__F1 | Cytokines, hormones or growth factors that activate Stat5 |
| PMC2976970__F3 | Protein-protein interaction map of Notch transcription modifiers |
| PMC2978002__F7 | Model demonstrating the specific apoptotic effect of SREBP-1 and FAS inhibition on GBM cells bearing EGFRvIII |
| PMC2978223__F1 | Daphnia pulex insulin and TOR signalling pathways, adapted from Drosophila melanogaster [] |
| PMC2978721__F8 | Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells |
| PMC2978917__F7 | Signaling pathway and transcription factors involved in HPR1 gene expression in cancer |
| PMC2980759__F1 | Examples of the inter-relationship between host, tumor, and environmental factors (pharmaco-epi-bio-genomic triad) that determine the response to tamoxifen in an individual patient (phenotype) |
| PMC2981059__F6 | HER/HER2-PI3K-Akt-NFKB-elicited pathway in prostate cancer cells |
| PMC2981097__F2 | Double strand DNA repair: Homologous recombination and Non-homologous end joining |
| PMC2981143__F1 | Folate metabolism and its contributions to physiological processes |
| PMC2981398__F1 | Role of the N-end rule pathway in RGS protein degradation |
| PMC2981456__F1 | The estrogen biosynthesis pathway |
| PMC2981460__F1 | TGFB canonical signal transduction pathway and transcriptional responses mediating TGFB growth inhibitory effects |
| PMC2981507__F2 | Therapeutic interventions for fragile X syndrome |
| PMC2981516__F6 | Demosponge EST Sequencing Reveals a Complex Genetic Toolkit of the Simplest Metazoans |
| PMC2981611__F1 | Wnt Signaling and Mammary Stem Cells |
| PMC2983087__F2 | Mechanisms of double-strand break repair in somatic mammalian cells |
| PMC2983445__F2 | Growth factor signaling pathways mediating proliferation in multipotential stromal cells |
| PMC2983445__F3 | Growth factor signaling pathways mediating survival in multipotential stromal cells |
| PMC2984239__F5 | Merged network pathway analysis of proteins involved in cellular assembly and organization, cellular compromise, and protein folding that were identified in cytoplasmic fraction |
| PMC2984446__F10 | PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells |
| PMC2984459__F1 | Schematic overview of Toll-like receptor (TLR)4 signaling pathway |
| PMC2984500__F2 | Selection of miRNA implicated in the TLR4 signalling pathway |
| PMC2984599__F1 | TP53 levels determine whether CDKN1A will orchestrate irreversible senescence or quiescence |
| PMC2984612__F1 | Cellular FLICE-inhibitory protein: an attractive therapeutic target?. |
| PMC2987346__F2 | RSK signaling pathway |
| PMC2987484__F1 | Pathway analysis on differentially expressed genes |
| PMC2988197__F4 | Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi |
| PMC2988681__F2 | Programming anoikis induction |
| PMC2988877__F2 | DNA Damage Response: Making it safe to play with knives |
| PMC2988877__F3 | The DNA Damage Response: Making it safe to play with knives |
| PMC2989404__F1 | Eighteen Insulin-like Growth Factor (IGF) pathway genes, circulating levels of IGF-1 and its binding protein (IGFBP-3), and risk of prostate and breast cancer |
| PMC2989631__F1 | DNA damage response (DDR) pathway |
| PMC2989646__F4 | The involvement of zinc metalloproteinases in AB metabolism |
| PMC2989686__F4 | Canonical pathways for cardiovascular disease |
| PMC2989726__F5 | CFTR Chloride Channel in the Apical Compartments: Spatiotemporal Coupling to its Interacting Partners |
| PMC2989866__F2 | The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review. |
| PMC2989879__F2 | The RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system |
| PMC2989879__F3 | The RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system |
| PMC2990064__F4 | Modeling Dose-response at Low Dose: A Systems Biology Approach for Ionization Radiation. |
| PMC2990406__F8 | A previously unknown miR-290-dependent pathway controls DNA methylation via Rbl2 and affects telomere integrity and telomere-length homeostasis |
| PMC2990476__F3 | Functional network identified by genes in the single nucleotide polymorphism (SNP) component using independent component analysis |
| PMC2990540__F1 | APC/C inhibition is regulated by signalling within the cytoplasm (a) and at the kinetochore (b) |
| PMC2990745__F1 | Examples of pathways shared by a signature hub from the Wang dataset and a signature hub from the Desmedt dataset |
| PMC2990976__F2 | TNFA signaling pathways to NFKB activation |
| PMC2990979__F1 | Portions of the pathway utilized in Beta-branching are highlighted with color in this depiction of the bryostatin biosynthetic pathway |
| PMC2991085__F2 | Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease |
| PMC2991311__F4 | Systems Biology Approach Uncovers Cellular Strategies Used by Methylobacterium extorquens AM1 During the Switch from Multi- to Single-Carbon Growth |
| PMC2991380__F1 | Retinoid Pathway and Cancer Therapeutics |
| PMC2991480__F5 | FC-66 expression of the Ingenuity NFKB Signaling canonical pathway |
| PMC2991541__F3 | Redox-control of Matrix Metalloproteinase-1: A critical link between free radicals, matrix remodeling and degenerative disease. |
| PMC2991775__F1 | Pathways leading to the type I interferon production |
| PMC2992267__F8 | A schematic model showing the proposed biosynthetic pathway for cutin |
| PMC2992289__F5 | KLA increases mRNA expression of genes involved in sphingolipid biosynthesis |
| PMC2992472__F4 | The regulatory network of apoptosis in BCL11B and its related genes |
| PMC2992886__F3 | Genes associated with autoimmunity regulate the CD40/NFKB signaling pathway |
| PMC2992967__F2 | Sonic hedgehog (SHH) pathway |
| PMC2993245__F2 | Negative regulation of junctional stability in RPE by the PI3K-ROS circuit |
| PMC2993603__F1 | A tincture of hepcidin cures all: the potential for hepcidin therapeutics |
| PMC2993607__F1 | RB tumor suppressor: a gatekeeper to hormone independence in prostate cancer? |
| PMC2993794__F1 | Stimuli and factors involved in yeast chronological aging |
| PMC2993798__F6 | A conserved insulin signaling pathway in C |
| PMC2993855__F2 | Pathways correcting DNA polymerase errors |
| PMC2994033__F1 | Signaling complexes are induced by TNFA to mediate NFKB activation, apoptosis, and necroptosis |
| PMC2994099__F1 | The Mre11 complex and Chk2 in apoptosis and tumor suppression |
| PMC2994209__F1 | HER receptors and their ligands |
| PMC2994272__F8 | Carnosol in human prostate cancer PC3 cell line |
| PMC2994781__F1 | Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis |
| PMC2994991__F6 | Reporter gene assay for HIF-1 activity |
| PMC2995293__F2 | Immune and central nervous systems interact and contribute to the etiology and pathophysiology of cytokine-induced depression |
| PMC2995824__F1 | Regulation of muscle protein synthesis |
| PMC2996094__F11 | Proposed model of GF-mediated regulation of IGFBP-3 |
| PMC2996105__F7 | Interaction of p75NTR and TrkB signaling |
| PMC2996236__F2 | Autoinflammatory disease regulated by IL-1B (inflammasomopathies) and NFKB |
| PMC2996236__F5 | Pathogenesis of the complement-mediated autoinflammatory disease atypical hemolytic uremic syndrome |
| PMC2996483__F3 | Oncogenic Notch1 Signalling |
| PMC2996902__F1 | CoQ10 biosynthesis pathway |
| PMC2997002__F2 | Gene list involved in TLR pathway generated by KEGG |
| PMC2997002__F3 | MAPK signaling pathways generated by GenMAPP |
| PMC2997006__F1 | Tor pathway in the model fungi Saccharomyces cerevisiae and Schizosaccharomyces pombe |
| PMC2997007__F5 | Candidate master switch molecules and signaling pathways involved in LPS-induced inflammatory response of monocyte THP-1 cells |
| PMC2997007__F6 | Identification of putative signaling regulators for immune-modification |
| PMC2997336__F1 | Model illustrating the signaling pathways activated by optimal DA and hyperdopamine |
| PMC2997522__F2 | Novel Therapies Against Aggressive and Recurrent Epithelial Cancers by Molecular Targeting Tumor- and Metastasis-Initiating Cells and Their Progenies. |
| PMC2997573__F1 | The current understanding of PELP1 signaling pathway |
| PMC2997602__F1 | Signaling cascade of class I and IIa HDACs in the development of cardiac hypertrophy |
| PMC2997737__F1 | AKT/MTOR pathway |
| PMC2997801__F1 | Positioning NFKB in multiple myeloma |
| PMC2998095__F7 | ID2 in clock resetting |
| PMC2998162__F2 | Schematics of the Hippo pathway in flies and mice |
| PMC2998292__F1 | Estrogen and Tamoxifen Metabolic Pathways depicted at the genomic level |
| PMC2998292__F2 | Pathway Analysis Models for the Tamoxifen (TAM) Pathway tested with data from the Placebo (P) and Tamoxifen (T) arms |
| PMC2998553__F3 | Screen shot of the user interfaceofSimmune2.0 |
| PMC2998559__F1 | Model Depicting major molecules and events in mast cell activation |
| PMC2998559__F2 | Syk Activation |
| PMC2999098__F3 | CKI members in canonical Wnt signaling |
| PMC2999229__F1 | Hypothetical model for the molecular signaling pathways of vasculogenic mimicry in tumors and anti-vasculogenic mimicry (VM) therapy strategies |
| PMC2999286__F1 | The involvement of the Unfolded Protein Response (UPR) signaling in lipid metabolism |
| PMC2999296__F2 | Toll-like recepter 4 signaling pathway modified from Wikipedia Commons |
| PMC2999341__F12 | Regulatory PathRNet Only nodes that are close to P38 MAPK Signaling pathway or "S-7" are kept (distance<3) |
| PMC2999349__F3 | Location of 2,4DNT impacted genes in the pathway association network |
| PMC2999475__F8 | Summary of metabolomic findings in Hnf1a-null mice |
| PMC2999593__F1 | Heme Biosynthetic Pathway |
| PMC2999931__F2 | Postsqualene cholesterol synthetic pathway |
| PMC3000288__F1 | Schematic representation of the As cycle in the environment and plants |
| PMC3000367__F5 | Scalable Approach for Discovering Conserved Active Subnetworks across Species |
| PMC3000440__F1 | Decorin effects as an antiproliferative (left panel) and proliferative (right panel) molecule |
| PMC3000610__F6 | Proposed working hypothesis |
| PMC3000682__F7 | Pro-inflammatory pathway induction by cAMP/PKA signaling in BSC-derived lesions |
| PMC3000836__F1 | Comparison of the DC-ATLAS Toll Like Receptor (TLR) 3 pathway with other pathway databases |
| PMC3000843__F1 | Schematic representation of chiral 3HV production via the threonine biosynthesis pathway in metabolically engineered E |
| PMC3001129__F2 | NOD-like receptor signaling beyond the inflammasome |
| PMC3001241__F1 | MHC class II antigen processing pathways containing P |
| PMC3001241__F2 | Toll-like receptor signaling pathways containing P |
| PMC3001303__F1 | mTOR signalling pathway |
| PMC3001555__F1 | Representation of the transduction pathway involved in Cd signaling |
| PMC3001886__F5 | Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response |
| PMC3001953__F2 | EGFR-mutated lung cancer: a paradigm of molecular oncology |
| PMC3002356__F6 | Proposed model of GS-mediated apoptosis in HNSCC cells |
| PMC3003198__F8 | Scheme illustrating the dynamic reciprocity between MMP9 and the Raf–MEK–ERK pathway, which determines whether cells would continue to proliferate or undergo acinar morphogenesis |
| PMC3003336__F4 | FLCN pathway |
| PMC3003620__F1 | PI3K/Akt signaling pathway |
| PMC3003706__F7 | Distinct B1 and B3 integrin pathways converge to regulate cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells |
| PMC3003905__F5 | Spontaneous-fusion-mediated cell reprograming is controlled by Beta-catenin levels in ESCs and not by their proliferation |
| PMC3003974__F3 | Protein interaction network of highly connected proteins associated with the cardiorenal syndrome |
| PMC3004266__F10 | Active Cdk1/cyclin B1 complex on the extrinsic death pathway |
| PMC3004331__F3 | Differential host transcriptional responses within the acute-phase response pathway in r1918-infected WT, TNFRKO, and IL1RKO mice at 1, 3, and 5 dpi |
| PMC3004338__F4 | Ingenuity Pathway Analysis (IPA) of differentially expressed genes between 24 DSS and 56 uncomplicated dengue patients |
| PMC3004523__F2 | Hypothetical roles for LAB-dependent positive signaling |
| PMC3004524__F4 | Model of pri-miRNA processing and localization |
| PMC3004666__F1 | Cetuximab in the treatment of colorectal cancer. |
| PMC3004747__F1 | Fucose is on the TRAIL of colon cancer |
| PMC3004842__F2 | Flux-sum intensity in Z |
| PMC3005023__F1 | Hypoxia and hypoxia-inducible factors (HIFs): master regulators of metastasis |
| PMC3005418__F8 | Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery |
| PMC3005738__F1 | Metabolic pathway of tamoxifen |
| PMC3006043__F3 | Colorectal Cancer Molecular Biology Moves Into Clinical Practice |
| PMC3006139__F6 | Subversion of Innate Defenses by the Interplay between DENV and Pre-Existing Enhancing Antibodies: TLRs Signaling Collapse |
| PMC3006290__F1 | Proposed signaling scheme for ischemic preconditioning |
| PMC3007169__F1 | Arsenic: a potentially useful poison for Hedgehog-driven cancers |
| PMC3008185__F1 | Two-loop model of iADE |
| PMC300841__F1 | Usurpation of the Ras signaling pathway by reovirus |
| PMC3008507__F5 | A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. |
| PMC3008616__F1 | EGFR pathway and its main downstream effectors (top) |
| PMC3008633__F1 | Examples of reaction-diffusion processes in muscle |
| PMC3009535__F3 | Functional module of the CXC chemokine pathway uniquely identified by NeMo |
| PMC3009741__F3 | Bioinformatics Analysis of Macrophages Exposed to Porphyromonas gingivalis: Implications in Acute vs. Chronic Infections |
| PMC3009898__F6 | Model for an alternative Okazaki fragment-processing pathway in vivo |
| PMC3010226__F2 | Cellular and molecular scheme for an adaptive immune axis leading to acute lung disease after viral infection |
| PMC3010252__F1 | Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanisms |
| PMC3010690__F2 | Zinc metalloprotease activity in APP processing |
| PMC3010754__F1 | Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors |
| PMC3010754__F2 | Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors |
| PMC3010981__F1 | Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells |
| PMC3011046__F2 | FAS generates an endogenous ligand for PPARA in liver |
| PMC3011108__F1 | Schematic showing that when a cell membrane is injured the arachidonic acid pathway is activated to initiate the local inflammatory response through the production of prostaglandins, thromboxanes, and leukotrienes |
| PMC3011268__F2 | Regulation of Wnt signaling in Xenopus CNC |
| PMC3011892__F1 | Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles. |
| PMC3011892__F4 | Cell cycle pathway containing Treponema denticola differentially regulated genes in calvarial bone compared with sham-infected controls at P ≤ 0.05, adapted from Pathway Express and using the Kyoto Encyclopedia of Genes and Genomes nomenclature |
| PMC3011892__F5 | Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles. |
| PMC3011942__F1 | Phosphatidylinositol 3-kinase-Akt (PI3K-Akt) pathway becomes activated via stimulation of receptor tyrosine kinases (RTKs) and the assembly of receptor-PI3K complexes |
| PMC3012004__F1 | PI3 kinase signaling pathway in glioma |
| PMC3012004__F2 | Sites of action for inhibitors and shRNAs in the EGFR-PI3K-Akt-mTOR pathway |
| PMC3012138__F3 | A network of hits highly enriched in cell cycle-related genes |
| PMC3012148__F2 | Biosynthetic pathway of sphingolipids that mediate expressions of genes associated with cellular processes in cancer |
| PMC3012182__F1 | TRPM channels in insulin secretion |
| PMC3012432__F7 | Diagram illustrating the PS-Tyro3-Akt cell survival signaling pathways |
| PMC3013016__F8 | The molecular mechanisms employed by the Ras/MAPK pathway to regulate mTORC1 signaling |
| PMC3013041__F5 | Relationship between transcription factors and their regulatory factors |
| PMC3013117__F4 | Thrombin Induces Macrophage Migration Inhibitory Factor Release and Upregulation in Urothelium: A Possible Contribution to Bladder Inflammation |
| PMC3013243__F9 | Myeloid-specific GPCR kinase-2 negatively regulates NFKB1p105-ERK pathway and limits endotoxemic shock in mice |
| PMC3013516__F8 | The interaction between cPLA2A and TGFBsignaling pathways in hepatic cells |
| PMC3013518__F1 | Vitamin D3 biotransformation pathway |
| PMC3013804__F3 | Case study of the discovered phosphorylation networks associated with insulin signaling pathway |
| PMC3014093__F3 | Upper panel |
| PMC301421__F1 | Schematic showing branching in the early steps of the bile acid synthesis pathways |
| PMC3014256__F3 | A-Kinase Anchoring Proteins: Getting to the heart of the matter |
| PMC3014294__F1 | Organizing signal transduction through A-kinase Anchoring Proteins (AKAPs) |
| PMC3016145__F1 | Intracellular and extracellular chromogranin/secretogranin actions |
| PMC3016890__F1 | The p38MAPKsignalling pathway |
| PMC3016978__F6 | Model for a meiotic gene regulatory cascade initiated by inactivation of a pathway that promotes turnover of meiotic transcripts produced in vegetatively growing cells |
| PMC3017081__F3 | Crosstalk between interleukin signalling pathways |
| PMC3017081__F4 | Cell cycle G1/S check point subnetwork |
| PMC3017463__F4 | Schematic illustartion of microglial (A) and astrocytic (B) events taking place in the spinal cord in neuropathic pain |
| PMC3017607__F2 | The kinetic framework for programmed –1 ribosomal frameshifting |
| PMC3017908__F6 | Major pathways affected in NMSC |
| PMC3018096__F1 | Adapters in the organization of mast cell signaling |
| PMC3018162__F1 | Schematic and mathematical representations of the main model assumptions |
| PMC3018488__F1 | Simplified scheme of SAM synthesis and its involvement in arsenic and DNA methylation |
| PMC3018616__F1 | TGFB superfamily signaling pathway |
| PMC3018769__F8 | Composite figure from all time points of microarray data showing apoptotic pathways in HepG2 cells when exposed to PCB-153 (70µM) and PCB-77 (70µM) |
| PMC3018793__F10 | Foxo3 regulation of hematopoietic progenitor cell activity |
| PMC3019079__F1 | The homocysteine and folate metabolic pathway |
| PMC3019561__F2 | Mitochondria and the synthesis of phospholipids |
| PMC3020075__F1 | GPC5 Gene and Its Related Pathways in Lung Cancer |
| PMC3020905__F6 | Molecular Basis for Vulnerability to Mitochondrial and Oxidative Stress in a Neuroendocrine CRI-G1 Cell Line |
| PMC3021097__F2 | Functional significance of itpkc_3 on ITPKC mRNA and Ca2+/NFAT pathway |
| PMC3021128__F7 | Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7 |
| PMC3021368__F2 | PI3K in immune system |
| PMC3021368__F5 | Foxo3 controls DCs functions |
| PMC3021511__F2 | Activity-based protein profiling for biochemical pathway discovery in cancer |
| PMC3021862__F4 | Genes regulated by Survivin in ITD-Flt3+KSL cells and deregulated in LSC are mapped on functional signaling network associated with epidermal growth factor receptor signaling pathway |
| PMC3021987__F1 | O-3223 synthesis pathway |
| PMC3021995__F3 | Post-transcriptional control of mammalian clock genes |
| PMC3022001__F12 | Schematic representation of effect of depletion of the syntaxin-5 complex on the autophagic pathway |
| PMC3022058__F1 | Outline of UDP-GlcNAc synthetic pathways |
| PMC3022184__F2 | A proposed mechanism of TGFA/EGFR/ras-MAPK activation loop in HNSCC |
| PMC3022188__F1 | Rationale for dual treatment targeting the IGF-1R signaling pathway in RMS |
| PMC3022256__F2 | Patterning the DV axis in Drosophila and Tribolium |
| PMC3022486__F9 | Alcohol-induced TLR4 protein recruitment mediates the activation of Src kinase signaling pathway |
| PMC3022513__F1 | Physiological regulation of the mTOR signaling pathway |
| PMC3022727__F6 | IPA pathway graphical representation of Aryl Hydrocarbon Receptor Signaling |
| PMC3022823__F7 | FBPA clustering on gene expression after direct irradiation |
| PMC3022823__F9 | FBPA clustering on gene expression in the bystander response |
| PMC3023029__F2 | Intracellular transport pathway of Shiga toxin |
| PMC3023199__F3 | PPARG ligand treatments increase expression of mitochondria-associated metabolic pathways in adipose tissue |
| PMC3023199__F4 | Dysregulated expression of fatty acid and cholesterol synthesis genes in liver is reversed by PPARG ligand treatments |
| PMC3023296__F3 | Cell cycle, cellular growth and proliferation pathways detected by ingenuity pathways analysis |
| PMC3023470__F9 | Schematic illustration of the sphingolipid metabolic pathway in CHO cells expressing SPHK1/2 and hSPNS2 |
| PMC3023527__F7 | Schematic summary of the results showing the consequences of mPGES-1 mediated PGE2synthesis for LPS-induced neuroinflammation |
| PMC3023586__F1 | Host-cell signalling induced by EPEC Tir |
| PMC3023615__F2 | In fibroblasts, Nod2 senses bacteria at the plasma membrane and recruits the autophagic machinery through direct interaction with ATG16L1 |
| PMC3023986__F2 | Wnt Signaling as a Therapeutic Target for Bone Diseases |
| PMC3024228__F1 | General pathway for phosphatidylinositide (PI) synthesis |
| PMC3024251__F6 | Downregulation of miR-342 is associated with tamoxifen resistant breast tumors. |
| PMC3024260__F1 | Computational and Experimental Study of the Regulatory Mechanisms of the Complement System |
| PMC3024731__F2 | Examples of the signaling role of Cdc42 in selective tissue cell types |
| PMC3025359__F1 | Mincle- and Dectin-1-mediated signalling in response to mycobacteria |
| PMC3025384__F2 | JAK/STAT3 signaling pathway transmits information from cytokine/chemical signals outside the cell, through the cell membrane, and into the gene promoters on the DNA in the cell nucleus, which causes DNA transcription and activity in the cell |
| PMC3025384__F3 | Wnt signaling plays central role in embryogenesis and human diseases including cancers |
| PMC3025434__F1 | Simplified overview of the pathways involved in miRNA regulation of gene expression in addiction |
| PMC3025468__F11 | Compartmentalization of TNF-R1 signalling and A-SMase activation |
| PMC3025702__F2 | Combination Treatment with Progesterone and Vitamin D Hormone May Be More Effective than Monotherapy for Nervous System Injury and Disease |
| PMC3025761__F1 | Schematic illustration of the various steps involved in the ubiquitin proteasome pathway and general architecture of the cullin 1 (CRL1) and cullin 4 (CRL4)-based E3 ubiquitin ligases |
| PMC3025764__F4 | Metabolic regulation by FOXO1 in skeletal muscle |
| PMC3025834__F1 | Schematic representation of xylose metabolic pathway in metabolically engineered S |
| PMC3026473__F2 | Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets |
| PMC3026729__F7 | Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice |
| PMC3026934__F2 | Signaling pathway induced by Dectin-1 |
| PMC3026989__F1 | The innate immune induction pathway through RLR activation |
| PMC3026990__F5 | Signaling networks associated with PPARD and inflammatory and invasive gene expression |
| PMC3027010__F1 | Schematic review of the molecular mechanisms linking diabetes mellitus and colorectal cancer |
| PMC3027044__F7 | Cholesterol synthesis pathway, associated diseases and putative pathogenic mechanisms (reviewed in refs |
| PMC3027158__F7 | Biological network of genes linked to the canonical pathway "molecular mechanisms of cancer" that were hypomethylated (fold change >1.5) in zebrafish hepatocellular carcinoma compared to healthy liver |
| PMC3027158__F8 | Ingenuity network predicted for genes that were both hypomethylated and increased in expression in zebrafish HCC (shaded red) |
| PMC3027599__F5 | Ingenuity pathway Analysis network 1 depicting relationships among up-regulated genes in SB300 infection group relative to that of SB1117 infection group at 8 hours |
| PMC3027599__F6 | Ingenuity Pathway Analysis Network 2 depicting relationship among up-regulation Genes in SL1344 vs SB1117 infection groups at 8 hours |
| PMC3028588__F2 | Validating cancer drug targets through chemical genetics |
| PMC3028977__F6 | CD36 contributes to inflammation and impaired insulin signalling in adipocytes and macrophages |
| PMC3030591__F4 | Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte |
| PMC3030591__F7 | Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte |
| PMC3030666__F2 | Impact of Aging on Dendritic Cell Functions in humans |
| PMC3030733__F1 | Interventions in nuclear factor erythroid 2-related factor 2-Kelch-like ECH-associated protein 1 signaling pathway |
| PMC3030971__F1 | Key proteins and pathways in the replication stress response network |
| PMC3031055__F3 | TFM-C-induced alteration to IL-12p40 chaperone interactions |
| PMC3031466__F10 | A PtdIns(3)P-mediated signaling pathway that drives the degradation of apoptotic cells |
| PMC3031497__F7 | Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer |
| PMC3031501__F8 | Ablation of Akt2 Induces Autophagy through Cell Cycle Arrest, the Downregulation of p70S6K, and the Deregulation of Mitochondria in MDA-MB231 Cells |
| PMC3031545__F8 | Regulation of Brown Fat Adipogenesis by Protein Tyrosine Phosphatase 1B |
| PMC3031560__F5 | Identification of Novel Molecular Targets for Endometrial Cancer Using a Drill-Down LC-MS/MS Approach with iTRAQ |
| PMC3031865__F4 | Molecular mechanisms activated by tumor necrosis factor-alpha (TNFA) which causes hypercontractility of cavernosal smooth muscle cells |
| PMC3031870__F1 | MTORC1 and mTORC2 signaling branches |
| PMC3032036__F10 | The paracellular pathway in vertebrates and insects |
| PMC3032315__F3 | Regulation of peripheral tolerance by the intrinsic and extrinsic apoptosis pathways in T and B cells |
| PMC3032410__F7 | Dynamic Distribution of CARD11 at the Immunological Synapse is Regulated by the Inhibitory Kinesin GAKIN |
| PMC3032466__F11 | Expression of cell cycle genes in wild-type (WT) and CKX-4 tubers after GA3-mediated tuber sprouting |
| PMC3032584__F1 | NF-kappaB, a mediator for lung carcinogenesis and a target for lung cancer prevention and therapy |
| PMC3032697__F15 | Time course changes in cytokine network pathways of lungs from 9 V/null mice |
| PMC3033145__F2 | Anticoagulant properties of endothelial cells |
| PMC3033158__F3 | Signal pathways in systemic regulation of hepcidin |
| PMC3033173__F2 | LMP1 in promoting survival in PTLD |
| PMC3033586__F2 | Wnt pathway and its regulation of Beta-catenin in stem cells and cancer |
| PMC3033586__F3 | Hypothetical scheme for bacteria-regulated intestinal stem cells and tumorigenesis |
| PMC3033602__F1 | Adapted from KEGG colorectal cancer pathway [, , ] |
| PMC3033967__F8 | Structural Characterization of the Polar Lipids of Clostridium novyi NT. Further Evidence for a Novel Anaerobic Biosynthetic Pathway to Plasmalogens |
| PMC3034442__F3 | Glycine synthesis and degradation |
| PMC3034644__F2 | Self-regulation in Xenopus dorsal-ventral patterning.The pathway consists of a network of BMP-interacting proteins |
| PMC3035032__F3 | Simplified schematic illustrating molecular mechanisms of neurite regulation |
| PMC3035094__F6 | Cic regulatory elements mediate Torso and EGFR responses |
| PMC3035137__F2 | Effects of Hfe deficiency and the associated low hepcidin and intracellular iron levels on macrophage TLR4 signaling |
| PMC3035360__F1 | Synthetic view of the p53 pathway |
| PMC3035565__F11 | WNKs: atypical protein kinases with pleiotropic actions |
| PMC3035594__F3 | Integrated view of Wnt pathway |
| PMC3035636__F1 | Targeting Metabolic Remodeling in Glioblastoma Multiforme |
| PMC3035679__F3 | Human inherited and mouse experimental defects in the cholesterol biosynthesis pathway that cause myelin disorders |
| PMC3035679__F4 | Human inherited and mouse experimental defects in the glycosphingolipids synthesis pathway that cause myelin disorders |
| PMC3035754__F1 | Regulatory network governing mitochondrial functions orchestrated by PGC-1A |
| PMC3035824__F5 | Mapk signaling pathway from KEGG |
| PMC3035871__F2 | Targeting Fas in osteoresorptive disorders |
| PMC3035920__F1 | Recent insights into iron homeostasis and their application in graminaceous crops |
| PMC3035969__F5 | Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression |
| PMC3035979__F2 | Gene expression profile |
| PMC3035994__F1 | Simplified model of nutrient signaling pathways influencing metabolic responses |
| PMC3036164__F8 | Alcama mediates Edn1 signaling during zebrafish cartilage morphogenesis |
| PMC3036178__F1 | Lymphotoxin and the immediate tumor necrosis factor (TNF) family |
| PMC3037032__F4 | The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes |
| PMC3037521__F2 | Selective elimination of messenger RNA underlies the mitosis-meiosis switch in fission yeast |
| PMC3037729__F1 | Interaction between PI3K/Akt and Wnt signaling pathways mediates diverse cellular effects through downstream messengers |
| PMC3037747__F2 | Cyclin D1, at the center of MCL pathogenesis |
| PMC3037747__F4 | BCR, NFKB, and PI3K/AKT/mTOR deregulation in MCL |
| PMC3037835__F5 | Major pathways of lipid metabolism in yeast |
| PMC3038050__F1 | Mechanisms by which CD44 can modulate cell death |
| PMC3038089__F2 | Biological consequences of methylation on Rho-RhoGDI interaction |
| PMC3038181__F1 | Activation of the PI3K/Akt pathway in cancer |
| PMC3038194__F1 | Therapeutic strategies and mechanisms of tumorigenesis of HER2-overexpressing breast cancer |
| PMC3038250__F4 | PI3K/Akt and RAS/BRaf/MEK pathways are frequently altered in melanoma |
| PMC3038847__F1 | Development of Delivery Methods for Carbohydrate-based Drugs: Controlled Release of Biologically-active Short Chain Fatty Acid-Hexosamine Analogs |
| PMC3039108__F12 | Model diagrams outlining potential brain substrates and mechanisms that underlie sickness behavior in response to systemic inflammatory insult (LPS challenge) |
| PMC3039688__F7 | Mapping Protein Interactions between Dengue Virus and Its Human and Insect Hosts |
| PMC3039708__F2 | T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics |
| PMC3039708__F3 | T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics |
| PMC3039745__F1 | TRAF6 and A20 control K63-linked ubiquitination of Beclin 1 to trigger autophagy |
| PMC3039924__F1 | Insulin-like growth factor receptor 1 (IGF1R) signaling pathway and potential mechanisms of resistance to IGF1R blockade (red asterisks) |
| PMC3039927__F1 | Organellar Ca2+ buffering and intracellular Ca2+ dynamics |
| PMC3039931__F1 | Cytoplasmic tyrosine kinases in the activating signaling pathways utilizing ITAM-containing adapters |
| PMC3039931__F2 | Tyrosine kinase pathways leading to CARD9 and TLR signaling responses |
| PMC3039931__F3 | Inhibitory pathways in innate cells utilizing ITIM or "inhibitory" ITAM signaling pathways |
| PMC3039968__F2 | Regulatory Processes Linked to PL Metabolism |
| PMC3040416__F3 | Proteins oxidized by extracellular EhCySS control cell signaling and morphology |
| PMC3040753__F3 | Gene Expression Profiling of Vasoregression in the Retina–Involvement of Microglial Cells |
| PMC3041769__F4 | Antibodies against CD20 or B-Cell Receptor Induce Similar Transcription Patterns in Human Lymphoma Cell Lines |
| PMC3042129__F8 | Unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening |
| PMC3042531__F3 | Regulation of Innate Immunity by signaling pathways emerging from the endoplasmic reticulum. |
| PMC3042643__F1 | EGFR signaling pathway |
| PMC3042723__F2 | Signaling pathways regulating dendritic spine actin remodeling with the induction of LTP by theta burst stimulation (TBS).Schematic of signaling pathways linking three classes of synaptic to regulation of the actin cytoskeleton |
| PMC3042730__F2 | Inflammatory signals regulate hematopoietic stem cells |
| PMC3042782__F2 | Models for HJV cleavage by furin-like activity and matriptase-2 |
| PMC3043094__F2 | Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach |
| PMC3043094__F3 | Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach |
| PMC3043094__F4 | Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach |
| PMC3043160__F4 | Calcium-mediated mechanisms of cystic expansion |
| PMC3043245__F3 | Signalling between p53 and the IGF-AKT-mTORC1 pathway |
| PMC3043627__F1 | Simplified model for the intersection of signaling pathways regulating protein synthesis and degradation |
| PMC3043796__F1 | Signaling pathways activated by endothelin-1 (ET-1) in vascular smooth muscle cells (VSMC) |
| PMC3043796__F3 | Proteins of signaling pathways activated by ET-1 are targets for O-GlcNAc |
| PMC3044050__F6 | Spry2 and Spry2Y55F function in the context of EC MAPK signaling |
| PMC3044157__F6 | The Nuclear Guanine Nucleotide Exchange Factors Ect2 and Net1 Regulate RhoB-Mediated Cell Death after DNA Damage |
| PMC3044403__F1 | The GlcNAc and GalNAc salvage and O-GlcNAc signaling pathways |
| PMC3044438__F3 | Identifying genomic and developmental causes of adverse drug reactions in children |
| PMC3044944__F6 | Hypothetic model for TGF-Beta-regulated KLF4 proteolysis |
| PMC3045367__F1 | Exploring the Evolutionary Relationship of Insulin Receptor Substrate Family Using Computational Biology |
| PMC3045450__F4 | NAViGaTing the Micronome - Using Multiple MicroRNA Prediction Databases to Identify Signalling Pathway-Associated MicroRNAs |
| PMC3045483__F1 | Interactions occuring in the ovarian mural granulosa cells (GC) and cumulus cells (CC) after the administration of hCG for ovulation induction |
| PMC3045531__F9 | Snail repressor is required for PMC ingression in the sea urchin embryo |
| PMC3045562__F1 | Neural pathway for habituation in response to odors |
| PMC3045692__F4 | Network of genes commonly regulated after pioglitazone treatment |
| PMC3045854__F1 | Memory genes identified in model systems overlap with genes identified in human mental retardation |
| PMC3046044__F1 | Molecular mechanisms involved in nasopharyngeal carcinoma (NPC) development |
| PMC3046063__F7 | Proposed working model and protein-protein interaction map |
| PMC3046155__F6 | Lipid Pathway Alterations in Parkinson's Disease Primary Visual Cortex |
| PMC3046427__F2 | Beta-Catenin is at the hub of multiple signaling pathways |
| PMC3046528__F6 | Monosodium urate (MSU)-mediated inflammation and the roles of spleen tyrosine kinase (Syk) and Nlrp3 |
| PMC3046639__F1 | RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it |
| PMC3046768__F2 | Schematic of the base excision repair pathways present in mitochondria |
| PMC3046919__F7 | Proposed model of the process of A20 |
| PMC3047044__F1 | Simplified schematic version of the epidermal growth factor receptor (EGFR) signaling cascade |
| PMC3047086__F9 | Suggested modes of the involvement of Nrf2/ARE in the regulation of AML cell differentiation |
| PMC3047110__F6 | Proposed model for ERG functions in prostaglandin signaling pathway |
| PMC3047474__F1 | Architecture of intestinal TD and TI IgA responses |
| PMC3047474__F2 | Innate IgA-inducing signaling pathways |
| PMC3047603__F3 | CYP17 inhibitors for prostate cancer therapy |
| PMC3047613__F2 | Model: The kinase IKK may activate Htt degradation by a mammalian version of the yeast Cvt pathway |
| PMC3047627__F3 | RECK pathway in stromal-epithelial interaction in prostate cancer |
| PMC3047755__F7 | Proposed model for how Shh signaling pathway negatively regulates its mitogenic potential through Beta-arrestin 1 |
| PMC3047785__F5 | CD28 signaling events |
| PMC3047798__F1 | Ubiquitin-mediated regulation of the core Wnt pathway components APC, Axin and Beta-catenin |
| PMC3047798__F3 | Wnt signaling components regulate ubiquitylation |
| PMC3048376__F2 | Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli |
| PMC3048376__F5 | Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli |
| PMC3048376__F9 | Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli |
| PMC3048459__F3 | TGFB Smad-dependent signaling pathway: TGFB exerts its effect by binding and activating type II receptor (TGFBR2) and then type I receptor (TGFBR1) |
| PMC3048558__F7 | Proposed mechanism of gene regulation in response to extracellular and intracellular dsRNA stimulation |
| PMC3048826__F12 | Signaling pathway of HMGB1-mediated ischemia reperfusion injury |
| PMC3048826__F8 | Hsp72 regulates oxidative stress-induced HMGB1 cytoplasmic translocation and release |
| PMC3048826__F9 | Hsp72 is an important intracellular protein to inhibition of HMGB1 release and proinflammatory function in macrophages () |
| PMC3048839__F10 | Schematic representation of IH-induced increase in adrenal medullary NPY by activation of reactive oxygen species (ROS) signaling pathway |
| PMC3048914__F6 | Differentially expressed genes in the MICs as compared to NSPCs |
| PMC3049118__F3 | Endocrine system development and function genes increase in the spleen of CVB3 infected males at 12 h pi |
| PMC3049118__F6 | Cardiovascular disease genes increase in the spleen of CVB3 infected males at 12 h pi |
| PMC3049195__F1 | Proposed diphthamide biosynthesis pathway |
| PMC3049335__F1 | The Nrf2 pathway in PD pathogenesis |
| PMC3049553__F1 | MAPK pathway activation in melanoma |
| PMC3049838__F3 | Wnt signaling pathway activation in R1A deficient tumor cells |
| PMC3049852__F1 | Multifunctional effects of CMKLR1 activation |
| PMC3049961__F8 | Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ÃŽâ€EGFR |
| PMC3050428__F2 | Tumor Microenvironment in Hepatocellular Carcinoma: Current Status and Therapeutic Targets |
| PMC3050844__F5 | Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection - A Meta-Analysis of Genomic Signatures in Circulating Leukocytes |
| PMC3050939__F3 | Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis |
| PMC3051001__F1 | RIP1 COMES BACK TO LIFE AS A CELL DEATH REGULATOR IN TNFR1 SIGALING |
| PMC3051174__F3 | TLR4 signaling - a converged immune response pathway for hemorrhagic shock and septic shock |
| PMC3051184__F9 | Proposed model explaining upregulation of CREB expression by RA in NHTBE cells |
| PMC3051261__F11 | Schematic Models of Tap46/Tap42/A4 Functions in TOR Signaling Pathways in Eukaryotes.(A) TOR signaling in yeast |
| PMC3051378__F5 | Resulting endoplasmic reticulum (ER) stress and unfolded protein response (UPR) gene network from a modelling approach using the set of differentially regulated genes common to all pancreatic cancer cell lines after nemorosone treatment |
| PMC305326__F1 | The development, activation, and maintenance of the satellite cell |
| PMC3053348__F7 | The Danger Signal S100B Integrates Pathogen- and Danger-Sensing Pathways to Restrain Inflammation |
| PMC3053440__F1 | Toll-like receptor signaling pathway |
| PMC3055312__F1 | Signaling pathways regulating GSK3 and functions of GSK3 related to mood regulation |
| PMC3055447__F4 | A schematic diagram of pyramidal cells (triangular) and GABAergic interneurons (square) within the trisynaptic pathway of the hippocampus |
| PMC3055758__F8 | Mechanism of cAMP inhibition of MAPK activity |
| PMC3055988__F2 | Further implications of G-/GM-CSF-induced JAK-STAT signaling in peripheral sensory neurons |
| PMC305600__F7 | An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity |
| PMC3056121__F1 | Regulatory natural autoantibodies to apoptotic cells: Pallbearers and protectors |
| PMC3056141__F1 | DNA-mediated activation of innate immune signaling |
| PMC3056511__F7 | Schematic summarizing the present findings |
| PMC3056800__F7 | Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds |
| PMC3057147__F1 | Top associated network functions for miR-141 and miR-200c |
| PMC3057165__F1 | Pathways by which toll-like-receptor signals and ligation of FcG receptor lead to the production of interleukin |
| PMC3057180__F1 | Backup DNA repair pathway |
| PMC3057180__F2 | Exploiting synthetic lethal interactions for the treatment of human cancer |
| PMC3057356__F2 | Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism |
| PMC3057454__F2 | Autophagy in Immunity and Cell-Autonomous Defense Against Intracellular Microbes |
| PMC3057579__F9 | Hypothetical diaphragm of HS7 induced apoptosis and inhibition of Wnt/Beta-catenin signaling pathway in HT-29 colon cancer cells |
| PMC3057977__F3 | Comparison of Expression Profiles in Ovarian Epithelium In Vivo and Ovarian Cancer Identifies Novel Candidate Genes Involved in Disease Pathogenesis |
| PMC3058199__F6 | Noonan syndrome and clinically related disorders |
| PMC3058235__F1 | Control of GnRH secretion by growth factors and small molecules produced by glial cells |
| PMC3058357__F3 | GRAIL and Otub1 regulation by the mTOR pathway controls naïve CD4 T cell proliferation |
| PMC3058380__F5 | Focal adhesions in osteoneogenesis |
| PMC3058407__F1 | Antiviral apoptotic pathway is mediated by IRF-3 and Bax |
| PMC3058926__F4 | Proof of Concept: A review on how network and systems biology approaches aid in the discovery of potent anticancer drug combinations |
| PMC3058926__F5a | Proof of Concept: A review on how network and systems biology approaches aid in the discovery of potent anticancer drug combinations |
| PMC3058986__F8 | Possible role of RACK1 in VEGF/Flt1-induced cell migration |
| PMC3059259__F2 | Autophagy, inflammation and neurodegenerative disease |
| PMC3059306__F1 | TSC mediated signaling in the central nervous system |
| PMC3059437__F1 | Shmt1 Heterozygosity Impairs Folate-Dependent Thymidylate Synthesis Capacity and Modifies Risk of Apcmin-Mediated Intestinal Cancer Risk |
| PMC3059560__F1 | Targeting the embryonic gene Cripto-1 in cancer and beyond |
| PMC3059752__F3 | Knowledge-based pathway analysis (Genomatix BiblioSphere Software) indicating the network of high BMI-associated genes |
| PMC3059896__F2 | Genetics and molecular pathology of Stargardt-like macular degeneration |
| PMC3060045__F2 | ErbB receptor signaling and regulation |
| PMC3060239__F5 | Model of the RBP-ROH/STRA6/JAK/STAT pathway |
| PMC3060320__F2 | Schematic illustration of signalling within the type I interferon (IFN) system |
| PMC3060380__F1 | Myostatin activity and muscle growth |
| PMC3060494__F6 | RPA/9-1-1- and hMSH2-mediated ATR activation in DNA damage signaling |
| PMC3060584__F6 | ‘Integrative Physiology 2.0’: integration of systems biology into physiology and its application to cardiovascular homeostasis |
| PMC3060774__F3 | Chromatin remodelling during development |
| PMC3060778__F4 | Comparative and demographic analysis of orangutan genomes |
| PMC3060875__F3 | Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses |
| PMC3060875__F5 | Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses |
| PMC3060878__F5 | FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways |
| PMC3060910__F1 | Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells |
| PMC3061041__F1 | Negative regulation of the IMD pathway |
| PMC3061066__F7 | Model demonstrating the possible mode of action of hSSB1 |
| PMC3061251__F1 | Viral infection triggers the IFNB signal transduction pathway of the host innate immune system, activating the antiviral state |
| PMC3061277__F1 | Simple schema of the IGF pathway and approaches to its inhibition |
| PMC3061395__F10 | The bifurcating parallel signal transduction pathways downstream of the IL-13R that regulate 15-LO gene expression in primary human monocytes |
| PMC3061506__F1 | Integration of the identified proteins into the canonical pathway of TLR signaling |
| PMC3061549__F1 | The classical and alternative selection pathways in the thymus |
| PMC3061571__F2 | Two different ubiquitin ligases control the stability of the Aurora-A and Polo-like kinases |
| PMC3061884__F7 | 100 frequent associations obtained after p value cut off in BLCA with CDCOCA |
| PMC3061884__F9 | 100 frequent associations obtained after p value cut off in MCL with CDCOCA |
| PMC3061960__F5 | NFKB activation in B cells |
| PMC3062054__F2 | Roles for Growth Factors in Cancer Progression |
| PMC3062054__F4 | Roles for Growth Factors in Cancer Progression |
| PMC3062410__F2 | Networks most highly represented by transcripts differentially associated with HuR after IR treatment |
| PMC3062534__F1 | Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort |
| PMC3062538__F5 | The regulation of IgA class switching. |
| PMC3062540__F7 | IL1B Induced Smad 7 Negatively Regulates Gastrin Expression. |
| PMC3062664__F1 | Metabolic insulin signaling pathway genes genotyped in the discovery cohort |
| PMC3063194__F1 | Elicitation of innate immune response in EBV infection |
| PMC3063194__F2 | Evasion of immune responses by individual EBV products |
| PMC3063577__F2 | Simplified diagram showing some of the identified BCR pathway members |
| PMC3063605__F1 | Simplified cartoon of PRR signaling in epithelial cells showing only the canonical pathway of NFKB activation and some of the key receptors, adaptors, and kinases involved |
| PMC3064126__F6 | PHEX, DMP1, matrix extracellular phosphoglycoprotein (MEPE), and ASARM peptides are proposed to dynamically regulate FGF23 expression in bone |
| PMC3064222__F9 | Proposed signal transduction pathways in NG following receptor activation with leptin and CCK-8 |
| PMC3064322__F5 | Model showing the regulation of PPARA by metabolism and PAR bZip transcription factors |
| PMC3064425__F2 | Dietary agents on the extrinsic and intrinsic pathways of apoptosis in prostate cancer |
| PMC3064559__F3 | Interconnectivity of signaling pathways emanating from TLRs and TACI |
| PMC3064560__F3 | Analogue 3 also showed potent antiproliferative activity against the highly invasive non-small-cell lung cancer cell line CL1-5 with an ED50 value of 0.11 µM |
| PMC3064629__F6 | miR-34a, MAGE-A genes, and p53 form a positive feedback loop modulating chemosensitivity in cancer cells |
| PMC3064843__F5 | DNA Repair Deficiency and Neurological Disease |
| PMC3064890__F4 | BRCA2/RAD51 pathway in response to DSBs |
| PMC3064890__F5 | BRCA2/RAD51 pathway in the response to stalled forks |
| PMC3064905__F3a | Genomic revelations of a mutualism: the pea aphid and its obligate bacterial symbiont |
| PMC3065454__F8 | Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer |
| PMC3065471__F3 | Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map |
| PMC3065553__F5 | Metabolic pathway for pitavastatin |
| PMC3065758__F1 | Biosynthesis of Sec and de novo synthesis of Cys |
| PMC3065765__F3 | Iron in regulating the mTOR signaling pathway |
| PMC3065826__F1 | Metabolism, Cell Surface Organization, and Disease. |
| PMC3066048__F1 | Complementation of Saccharomyces cerevisiae coq7 Mutants by Mitochondrial Targeting of the Escherichia coli UbiF Polypeptide |
| PMC3066060__F2 | Simplified schematic representation of the apoptosis pathway in mammals and Drosophila |
| PMC3066468__F7 | Scheme of cross-talk interactions between liver IR and TIM-1 signaling |
| PMC3066660__F6 | Significantly expressed genes in cytokine-cytokine receptor interaction pathway disturbed by SM at different time points |
| PMC3067333__F5 | Schematic presentation of Nag PTS and parts of the central metabolism of R |
| PMC3067813__F7 | Model of proposed HEB, GATA3, and Notch1 interactions |
| PMC3067914__F7 | Metabolic disturbance and pathway activation in the Acsl1T−/− heart |
| PMC3068086__F4 | Coordinately up-regulated TCA cycle genes in CD8+ T cells from the VIR group (VIR versus LTNP) illustrated in TCA cycle pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) |
| PMC3068086__F5 | Coordinately up-regulated cell cycle genes in CD8+ T cells from the VIR group (VIR versus BDL) illustrated in cell cycle pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) |
| PMC3068086__F6 | Branches of MAPK pathway significantly enriched in CD4+ T cells from the LTNP group (BDL versus LTNP) |
| PMC3068086__F7 | Schematic overview of the network of enriched pathways related to HIV disease progression |
| PMC3068163__F1 | Melanoma Molecular Disease Model |
| PMC3068308__F5 | TGFB signaling pathway |
| PMC3068476__F1 | Metabolic pathways of sphingolipid metabolism |
| PMC3068560__F4 | Proteome of sickle cell disease: insights from exploratory proteomic profiling |
| PMC3068924__F4 | CAERUS: Predicting CAncER oUtcomeS Using Relationship between Protein Structural Information, Protein Networks, Gene Expression Data, and Mutation Data |
| PMC3069071__F7 | Hedgehog Inhibition Promotes a Switch from Type II to Type I Cell Death Receptor Signaling in Cancer Cells |
| PMC3069496__F1 | miRNA biogenesis pathway |
| PMC3069685__F2 | An Activating Transcription Factor 5-Mediated Survival Pathway as a Target for Cancer Therapy |
| PMC3069698__F1 | The Fanconi Anemia and Breast Cancer Susceptibility Pathways |
| PMC3069698__F4 | The Fanconi Anemia and Breast Cancer Susceptibility Pathways |
| PMC3069769__F1 | Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy |
| PMC3069839__F5 | Regulation of Atm pathway genes after Rif-Phen-MCT |
| PMC3069928__F1 | Biological actions of IGF-1 are mediated by IGF-1R and modulated by IGFBPs |
| PMC3069932__F9 | Proposed role of Nodal in human placental development and mechanism of Nodal-regulated trophoblast invasion |
| PMC3070154__F1 | Estrogen Signaling in Hypothalamic Circuits Controling Reproduction |
| PMC3070284__F2 | Endothelial growth factor receptor (EGFR) signaling pathway |
| PMC3070484__F1 | iNKT cell autoreactivity: what is "self" and how is it recognized? |
| PMC3070553__F11 | Signaling modules identified by correlational analysis of end points |
| PMC3070572__F4 | Schematic analysis of the regulatory pathways in BOO in AROM+/6J male mice |
| PMC3070611__F3 | One experimental result of identified pathways from ovarian expression data |
| PMC3070611__F4 | One of experimental result from pathways intersection |
| PMC3070611__F5 | The shortest pathway identified by our system |
| PMC3070659__F1 | Representative axon regeneration-regulating pathways discovered in genetic model organisms |
| PMC3070842__F1 | Lessons on transcriptional control from the serum response network |
| PMC3070844__F3 | Top-scoring network created by Ingenuity Pathway Analysis |
| PMC3070849__F1 | Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation |
| PMC3070859__F1 | Cohesin regulates expression of genes that control differentiation, morphogenesis, proliferation, and pluripotency |
| PMC3070952__F1 | Essential features of the PERK signaling temporal delay circuit |
| PMC3071166__F3 | Hypothetical scheme of the proposed mechanisms contributing to the induction of tolerance by SIT |
| PMC3071501__F10 | Genes mapping to KEGG pathway for hedgehog signaling |
| PMC3071576__F2 | Proof of Concept Trials in Bipolar Disorder and Major Depressive Disorder: A Translational Perspective in the Search for Improved Treatments |
| PMC3071786__F6 | Changes in mRNA levels among various signalling pathway members following inhibition of FGFR activity |
| PMC3071831__F7 | Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures |
| PMC3071916__F2 | Insights into the Pathogenesis and Treatment of Cancer from Inborn Errors of Metabolism. |
| PMC3071979__F2 | Inhibition of NFKB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice |
| PMC3072047__F1 | Carbon flux rerouting during Mycobacterium tuberculosis growth arrest |
| PMC3072066__F5 | Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state |
| PMC3072659__F1 | Pathways that modulate canonical Wnt signaling |
| PMC3072784__F8 | A kinase cascade regulating pIgR transcytosis |
| PMC3073074__F1 | The pathway of propionyl-CoA to succinyl-CoA metabolism is displayed |
| PMC3073278__F1 | Tumor-induced DSB formation in vivo |
| PMC3073290__F1 | Models of how IFNB and GA activate PI3KD/Akt and MEK/ERK pathways to induce sIL-1Ra production in monocytes |
| PMC3073335__F2 | RNA helicases of the RIG-I-like receptor (RLR) family play a crucial role in the innate antiviral response |
| PMC3073350__F1 | Linking actin dynamics and gene transcription to drive cellular motile functions |
| PMC3073487__F4 | Functions of 14-3-3 in tumor-suppressor pathways |
| PMC3073545__F2 | Endocannabinoids in Liver Disease |
| PMC3073571__F8 | Cone-specific Visual Cycle |
| PMC3073693__F4 | Molecular pathways in dystonia |
| PMC3073741__F1 | Complement and Viral Pathogenesis |
| PMC3073781__F6 | Schematic overview of the MDM2 and p53 signalling pathway |
| PMC3073847__F1 | TGFB signaling pathway TGFB is secreted in a latent form and activation is mediated by several molecules including furin and emilin |
| PMC3073855__F1 | Childhood Obesity - 2010: Progress and Challenges |
| PMC3074148__F5 | Schematic representation of the two degradation pathways followed by MicA |
| PMC3074487__F8 | Migration of FGF7-stimulated epithelial cells and VEGF-A-stimulated HUVECs depends on EGFR transactivation by ADAM17 |
| PMC3074690__F1 | The current model of the blood coagulation cascade |
| PMC3074954__F1 | ROS have different origins |
| PMC3075071__F1 | Parsing out the complexity of RAF inhibitor resistance |
| PMC3075080__F3 | Proposed ACE2/ANG-(1-7)/Mas signaling pathways in the central nervous system |
| PMC3075242__F6 | Differential Expression of MicroRNAs in Tumors from Chronically Inflamed or Genetic (APCMin/+) Models of Colon Cancer. |
| PMC3075259__F4 | Data Integration Workflow for Search of Disease Driving Genes and Genetic Variants |
| PMC3075371__F1 | Local control of Beta-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient |
| PMC3075376__F1 | Targeting GSK-3 family members in the heart: A very sharp double-edged sword |
| PMC3075510__F9 | Phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3 (GSK3) signalling is required for expression of a subset of interleukin-10 (IL-10) inducible genes |
| PMC3075579__F4 | The PI3K pathway in TLR-signaling |
| PMC307558__F1 | TGFB signaling pathway |
| PMC3075605__F2 | NFKB signaling pathways downstream of TNFR1, TLR4 and TCR/CD28 |
| PMC3075645__F8 | DNA damage-triggered activation of SAPK/JNK at late times following cisplatin treatment |
| PMC3075710__F3 | Regulated fatty acid synthesis and metabolism during cell differentiation |
| PMC3076058__F2 | Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction |
| PMC3076281__F2 | Sphingolipid effects on intrinsic and extrinsic apoptotic pathways |
| PMC3076281__F3 | Effect of sphingolipids on the PI3K/AKT pathway |
| PMC3076503__F4 | Bioenergenesis neurotransmitter pathways with differentially expressed genes between frontal cortex and hippocampus |
| PMC3076503__F5 | Bioenergenesis neurotransmitter pathways with differentially expressed genes between frontal cortex and hypothalamus |
| PMC3076854__F2 | Global transcriptome analysis reveals CB1R-dependent, PHX-induced up-regulation of key cell-cycle proteins |
| PMC3076924__F2 | Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders |
| PMC3076924__F4 | Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders |
| PMC3077082__F1 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F2 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F3 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F4 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077082__F6 | Microbial manipulation of receptor crosstalk in innate immunity |
| PMC3077214__F1 | Signaling pathway components used to test gene-compound interactions |
| PMC3077220__F1 | Hepatitis C Virus NS2 Protein Triggers Endoplasmic Reticulum Stress and Suppresses its Own Viral Replication |
| PMC3077244__F5 | The proposed signalling pathway |
| PMC3077378__F7 | Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling |
| PMC3077393__F8 | GATA2 Mediates Thyrotropin-Releasing Hormone-Induced Transcriptional Activation of the Thyrotropin B Gene |
| PMC3077544__F2 | Akt regulates numerous biological functions by phosphorylating distinct protein substrates |
| PMC3077564__F3 | Activation of glia and neurons in the dorsal horn of the spinal cord after peripheral injury |
| PMC3077584__F6 | The effects of apoA-I on TNFA mRNA stabilization in LPS-stimulated macrophages |
| PMC3077649__F7 | Model of Egr-1/GGPPS/Erk1/2 pathway regulating insulin resistance in hyperinsulinism |
| PMC3077819__F2 | Widespread extracellular matrix (ECM) pathway silencing by DNA hypermethylation in colon cancer |
| PMC3077922__F3 | Gene expression changes in response to zebularine therapy in vivo |
| PMC3078022__F1 | Tumor heterogeneity and strategies to overcome kinase inhibitor resistance in cancer: Lessons from melanoma |
| PMC3078187__F1 | Signaling Cell Death from the Endoplasmic Reticulum Stress Response |
| PMC3078450__F5 | Network annotation of genes differentially expressed according to the CD133 status in HT-29 using ingenuity pathway analyses |
| PMC3078497__F1 | Effector signaling pathways activated during ischemia preconditioning |
| PMC3078503__F4 | PIKKs and TCR-associated pathways |
| PMC3078523__F2 | Heme Oxygenase-1, a Critical Arbitrator of Cell Death Pathways in Lung Injury and Disease |
| PMC3078731__F3 | Central prostate cancer-related processes and their miRNA-mediated regulation |
| PMC3079059__F1 | Control of intracellular heme levels: Heme transporters and Heme oxygenases |
| PMC3079294__F5 | SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition |
| PMC3079374__F1 | Simplified schematics of the MAPK and PI3K pathways in melanoma and the clinical compounds available for their inhibition |
| PMC3079441__F3 | Pharmacological activities of cardiotonic steroids such as ouabain |
| PMC3079783__F1 | Leptin Signaling in Intestinal Epithelium Mediates Resistance to Enteric Infection by Entamoeba histolytica |
| PMC3079800__F1 | Parenteral Nutrition Impairs Lymphotoxin B Receptor Signaling via NF- KB |
| PMC3079809__F7 | A RhoB-dependent endosomal trafficking pathway that couples RTK stimulation to Cdc42/Rac activation, localized actin dynamics, and cell migration |
| PMC3080176__F2 | Diagrammatic representation of the top three canonical signaling pathways, proposed by the Ingenuity Pathways Analysis program, associated with differentially expressed genes in the microarray dataset |
| PMC3080795__F2 | Scheme for CCM including main pathways - glycolysis/gluconeogenesis, penthaphosphate pathway, citrate cycle, overflow pathway |
| PMC3080846__F1 | Innate Immune Sensing of DNA |
| PMC3080858__F6 | PDP-1 Links the TGFB and IIS Pathways to Regulate Longevity, Development, and Metabolism |
| PMC3080979__F2 | Partial hepatectomy stimulates anandamide production through a pathway involving conjugation of arachidonic acid and ethanolamine by FAAH |
| PMC3081173__F4 | Cell adhesion molecules nectins and associating proteins: Implications for physiology and pathology |
| PMC3081180__F7 | The participation of MCP-1, TNFA, MMP-9, E-cadherin, and Beta-catenin in macrophage fusion |
| PMC3081368__F8 | HMGB factors are required for posterior digit development through integrating signaling pathway activities |
| PMC3081520__F2 | Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease |
| PMC3081520__F4 | Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease |
| PMC3081620__F1 | Representative cascade of the TGFB pathway |
| PMC3081824__F3 | Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing |
| PMC3081824__F5 | Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing |
| PMC3081924__F10 | Model for SENP2-mediated modulation of Mdm2 in regulating p53 |
| PMC3082271__F5 | NVN for Putative CHS-Mediated (CHS4) Medicarpin Biosynthesis.Nodes in the network resemble individual genes, and the connecting edges represent coexpressed links |
| PMC3082324__F7 | Serpinin formation, its signaling pathway, and PN-1-dependent biogenesis of secretory granules in (neuro)endocrine cells |
| PMC3082499__F2 | Mediators of the extrinsic pathway of PCD by Fas and TNFR-1 signaling |
| PMC3082499__F5 | Anti-apoptotic mechanisms of Akt |
| PMC3082552__F5 | Genes Influencing Circadian Differences in Blood Pressure in Hypertensive Mice |
| PMC3082570__F1 | Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line |
| PMC3082642__F3 | HBOT affects gene expression in the Nrf2 Pathway |
| PMC3082833__F1 | During innate immune activation via LPS-LPB-TLR4, a number of factors of the coagulation pathway are activated, creating the cooperative immuno-coagulative response |
| PMC3083114__F2 | p68/p72-dependent miRNA processing pathways |
| PMC3083340__F3 | Top network affected by MAA |
| PMC3083931__F1 | Canonical and noncanonical nuclear factorKB (NFKB) activation pathways |
| PMC3083942__F3 | Proposed model for Syk in mediating oxidative stress-induced calcium release |
| PMC3083951__F3 | A model (steps 1-4) for copper homeostasis in Schizosaccharomyces pombe (Schiz |
| PMC3083963__F1 | Brain-derived neurotrophic factor (BDNF) gene and stimulated intracellular signaling cascades after activation of tropomyosin-related kinase (Trk)B |
| PMC3083967__F5 | Key regulators of the mammalian target of rapamycin signaling pathway |
| PMC3084000__F1 | Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003) |
| PMC3084021__F1 | Conservation of the RB and Hippo signaling pathways in humans and fruit flies |
| PMC3084054__F1 | Synthesis-enabled functional group deletions to probe predicted intermolecular interactions involving the C41 carboxylic acid and/or the C19 mycosamine appendages of AmB |
| PMC3084093__F4 | Proteins encoding the CAF and tumor stroma-associated genes from seven different epithelial tumors share common involvement in the MAPK signaling pathway and focal adhesion |
| PMC3084258__F5 | Globular Adiponectin, Acting via AdipoR1/APPL1, Protects H9c2 Cells from Hypoxia/Reoxygenation-Induced Apoptosis |
| PMC3084294__F4 | The Complete Genome Sequence of 'Candidatus Liberibacter solanacearum', the Bacterium Associated with Potato Zebra Chip Disease |
| PMC3084393__F10 | Proposed diagram for Alpha-mangostin-induced apoptosis in COLO 205 cells |
| PMC3084988__F2 | TLR structure and signaling |
| PMC3085438__F5 | Working model for the role of CCN6 in breast cancer invasion |
| PMC3085544__F1 | Intracellular signaling by the leptin (LepRb - cyan) and insulin receptor (magenta) |
| PMC3085710__F4 | KEGG Pathway Map () |
| PMC3085878__F3 | TLR-induced microbial resistance |
| PMC3086058__F1 | Representation of genes of the vascular endothelial growth factor (VEGF) signaling pathway and the sites at which bevacizumab, sorafenib, sunitinib, brivanib, and cilengitide are known to act |
| PMC3086165__F1 | Pathway, enzymes and probes for proliferation imaging |
| PMC3086210__F9 | NH2-terminal Propeptide of Type I Procollagen Acts Intracellularly to Modulate Cell Function |
| PMC3086918__F1 | Mind the dbGAP: The Application of Data Mining to Identify Biological Mechanisms |
| PMC3087179__F5 | IL-4R Drives Dedifferentiation, Mitogenesis and Metastasis in Rhabdomyosarcoma |
| PMC3087601__F1 | Cellular and bacterial profiles associated with oral epithelium-microbiota interactions |
| PMC3087811__F8 | Schematic model for the role of TGFB signaling pathways in iTreg and Th17 cell development |
| PMC3087899__F6 | NFKB pathway activation via death receptor signaling |
| PMC3087924__F1 | Autophagy in macrophages |
| PMC308804__F4 | Visualizing protein interaction networks in HPRD |
| PMC3088084__F4 | Therapeutic effects can be monitored using DMR on scant cell populations |
| PMC308834__F1 | A representative example of a plant pathway in MetaCyc |
| PMC3088358__F7 | The extracellular network of proteins that control D-V patterning |
| PMC3088722__F6 | Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells |
| PMC3088996__F3 | Regulatory role of ATM in cellular responses to DNA DSB repair |
| PMC3089033__F8 | Diagram of the proposed cell survival signaling pathway in ER+ breast cancer cells with PI3KCA mutations and low phosphorylated Akt |
| PMC3089562__F7 | Proposed model of how endocardial Jarid2 expression regulates myocardial development |
| PMC3089575__F8 | Proposed interconnection between PE synthesis and conversion (PL interconversion triad) during LD biosynthesis |
| PMC3089810__F2 | Receptors, subcellular compartments and the regulation of peripheral B cell responses: the illuminating state of anergy |
| PMC3089878__F2 | Cholesterol transport in the CNS |
| PMC3089884__F5 | Chemokine Signaling Pathway |
| PMC3089921__F1 | mTOR activation supports cancer cell survival |
| PMC3089989__F2 | Gene expression pattern of the P38 MAPK signaling pathway |
| PMC3090136__F1 | Prostanoid biosynthesis and response pathway |
| PMC3090458__F3 | BAFF and APRIL signaling pathways in B cells |
| PMC309045__F1 | CRP-dependent (A) and CcpA-dependent (B) carbon catabolite repression pathways and the Ntr regulatory pathway (C) |
| PMC3090485__F1 | Diagram of the signaling pathway of T4 and T3 from the blood stream to the cells of the brain for enzymatic processing |
| PMC3091413__F4 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways based on the Caucasian population |
| PMC3091413__F5 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways based on the Asian population |
| PMC3091413__F6 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways |
| PMC3091413__F7 | Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways |
| PMC3091517__F1 | Ras/Raf/MEK/ERK Pathway and Potential Sites of Therapeutic Intervention with Small Molecule Membrane-Permeable Inhibitors |
| PMC3091517__F2 | Ras/PI3K/PTEN/Akt/mTOR Pathway and Potential Sites of Therapeutic Intervention |
| PMC3091517__F3 | Interactions between the Ras/Raf/MEK/ERK, Ras/PI3K/PTEN/mTOR and Wnt/Beta-Catenin Pathways that Result in the Regulation of Protein Translation and Gene Transcription |
| PMC3091524__F3 | Role of ATR- or ATM-dependent modulation of WRN function in promoting correct recovery from replication arrest |
| PMC3091595__F2 | Bcl-2 as an attractive target for modulating different modes of cell death in cancer therapy due to close communications with mediators of apoptosis, programmed necrosis, and autophagy |
| PMC3091668__F4 | Putative TLR signal pathway |
| PMC3091668__F5 | Putative TCR signal pathway |
| PMC3091670__F2 | Interferon signalling cascade |
| PMC3091670__F3 | Complement pathway |
| PMC3091682__F2 | Correlation of Predicted miRNA Targets with Hosts |
| PMC3091694__F6 | Toll-like Receptor signalling canonical pathway |
| PMC3091695__F3 | Stress-induced pathways in the PVN of the hypothalamus of DBA/2J (A) and C57BL/6 (B) mice |
| PMC3091753__F3 | Representative genes that responded to [BF/S+L/Ep] treatment |
| PMC3091762__F7 | IPA representation of the canonical pathway for leukocyte extravasation signalling in cluster 4, 24 hours post-infestation with P |
| PMC3091762__F9 | IPA representation of the complement system pathway enriched in cluster 6, 3 hours post-infestation with P |
| PMC3092098__F1 | The genes and pathways associated with Crohn's disease pathogenesis |
| PMC3092200__F9 | Hypothetic scheme of cell death induction pathway triggered roscovitine and CR8 in human neuroblastoma (NB) cells |
| PMC3092273__F1 | Complementary signaling pathways activated in human cancer cells |
| PMC3092277__F1 | Hippo signaling network in mammals |
| PMC3092286__F1 | Nonlinear signaling through the PI3K-Akt pathway |
| PMC3092522__F1 | HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies |
| PMC3092604__F1 | General scheme of the SBP in Tritryps |
| PMC3092604__F2 | Lipid remodeling pathways in mammals, yeast and T |
| PMC3092676__F4 | Emerging molecular functions of RASSF8 |
| PMC3092918__F1 | Metabolic network used for metabolic flux analysis |
| PMC3093193__F2 | Update on the regulation of mammalian melanocyte function and skin pigmentation |
| PMC3093412__F1 | Viperin Links Lipid Bodies To Immune Defense |
| PMC3093880__F8 | miR-122 and liver-related functions and diseases |
| PMC3093880__F9 | Associations among miR-122-identified targets |
| PMC3093976__F5 | Working model to explain the antidiabetic effect of Ad36 |
| PMC3094097__F3 | Examples of cellular receptors that sense infection and cell death |
| PMC3094203__F3 | Peroxisome proliferator-activated receptor G (PPARG) is a ligand-activated nuclear receptor with potent anti-inflammatory properties that modulates the immune inflammatory response |
| PMC3094296__F1 | KEGG pathways used for the influence approach |
| PMC3094730__F2 | Dendritic cell control of tolerogenic responses |
| PMC3094853__F1 | CHS-catalyzed synthesis of unnatural polyphenols from cinnamoyl-SNAc starter substrates with a) malonyl-CoA and b) methylmalonyl-CoA as extender units |
| PMC3095361__F9 | ROS, elicitor and hormone regulation of O3-induced CRKs |
| PMC3095455__F1 | Schematic representation of the apoptosis signaling pathway that indicates existence of three distinct signaling modules in the apoptotic intrinsic pathway |
| PMC3095674__F4 | Procarcinogenic Effects of Cyclosporine A are Mediated through the Activation of TAK1/TAB1 Signaling Pathway |
| PMC3095763__F1 | Toll-like receptor Signaling in Neural Plasticity and Disease |
| PMC3095770__F2 | Hypothalamic proopiomelanocortin processing and the regulation of energy balance |
| PMC3095949__F3 | Functional pathway analysis of the 28-gene prognostic signature using Ingenuity Pathway Analysis |
| PMC3095999__F2 | Literature-based connections among genes in altered modules of head and neck squamous cell carcinoma (HNSCC) |
| PMC3096022__F1 | Biochemical pathways leading to the synthesis of TAG and cholesterol |
| PMC3096054__F1 | miRNA biogenesis pathways and regulatory networks |
| PMC3096079__F1 | mTOR regulation pathway involved in hypoxia |
| PMC3096194__F1 | Cell cycle is controlled by the Rb pathway and p53 pathway |
| PMC3096494__F1 | Regulation of Interleukin-10 Gene Expression in Macrophages Engulfing Apoptotic Cells |
| PMC3096496__F6 | Model depicting the generation and consequences of ROS-mediated base damage |
| PMC3096649__F7 | IGF1R Signaling in Ewing Sarcoma Is Shaped by Clathrin-/Caveolin-Dependent Endocytosis |
| PMC3096731__F1 | Eph receptor and mTOR pathway crosstalk: implications for cancer |
| PMC309687__F10 | Postsenescence survival in telomerase-deficient (tlc1ÃŽâ€) budding yeast cells is controlled by three distinct Rad52-based homologous recombination pathways |
| PMC3096978__F4 | Functional network connections between HRneg/Tneg signature genes |
| PMC3097097__F2 | Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term |
| PMC3097115__F5 | PRP-17 and the pre-mRNA splicing pathway are preferentially required for the proliferation versus meiotic development decision and germline sex determination in Caenorhabditis elegans |
| PMC3097389__F1 | CoQ10 biosynthesis pathway |
| PMC3097472__F1 | Methionine, an essential amino acid required for protein synthesis, is the source of methyl groups for a number of methylation reactions such as methylation of nucleic acids, proteins, biogenic amines, phospholipids, and for creatine synthesis etc |
| PMC3097535__F4 | Global gene expression and Ingenuity biological functions analysis on PCB 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities. |
| PMC3097535__F5 | Global gene expression and Ingenuity biological functions analysis on PCB 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities. |
| PMC3097943__F1 | Role IL-6 signaling in CCA inflammation-related epigenetic regulation |
| PMC3098223__F1 | Integrative Analysis of Transgenic Alfalfa (Medicago sativa L.) Suggests New Metabolic Control Mechanisms for Monolignol Biosynthesis |
| PMC3098671__F2 | Endoplasmic-Reticulum Calcium Depletion and Disease |
| PMC3098789__F6 | Portion of the 'Toll-like Receptor Signaling' pathway for two representative cell lines |
| PMC3098994__F1 | Genetics of Mechanosensation in the Heart. |
| PMC3099033__F9 | Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling |
| PMC3099575__F5 | Model of relationship among Hfe, Tmprss6, and the Bmp/Smad signaling pathway in hepcidin regulation |
| PMC3099592__F2 | Activation of mast cells initiates a cascade of events resulting in Th2 polarization and both positive and negative feedback regulatory loops |
| PMC3099707__F10 | Dual MC4R signaling model to account for "rescue" of Ay phenotype by alterations in MC4R trafficking |
| PMC3099728__F8 | Molecular model of Foxo1 and IGF1/insulin regulation of osteocalcin expression |
| PMC3100327__F1 | De novo Biosynthesis of Biodiesel by Escherichia coli in Optimized Fed-Batch Cultivation |
| PMC3100630__F1 | EGFR biology |
| PMC3100722__F1 | The neuroendocrine (a), limbic (b), and brainstem (c) inter-related, stress-activated corticotropin releasing hormone (CRH) loops |
| PMC3100734__F1 | Induction of the Nrf2-ARE pathway under normal and pathological conditions: potential role of GSK-3B as a negative regulator of Nrf2 |
| PMC3100753__F4 | Regulation of the estrogen signaling pathway inside the nucleus |
| PMC3100780__F3 | Integration of BMP, FGF and Wnt signalling at the level of Smad1 during neural induction |
| PMC3100896__F1 | The two main pathways involved in estrogen-induced apoptosis regulation |
| PMC3100932__F1 | The HBP and chemical reporters of O-GlcNAc modification |
| PMC3101043__F2 | Endogenous and exogenous regulators of TLR activation |
| PMC3101238__F7 | Omeprazole Inhibits Proliferation and Modulates Autophagy in Pancreatic Cancer Cells |
| PMC3101816__F1 | The central role of cIAP1 in NFKB signalling and programmed cell death |
| PMC3101847__F1 | Pathways that regulate aging |
| PMC3101870__F1 | Three levels of regulation of the IGF-IR pathwayand its components |
| PMC3102606__F4 | Pathway context for RME modules found in glioblastoma |
| PMC3102695__F5 | Ciliary Neurotrophic Factor Induces Genes Associated with Inflammation and Gliosis in the Retina: A Gene Profiling Study of Flow-Sorted, Müller Cells |
| PMC3102743__F7 | Nodal-Dependent Mesendoderm Specification Requires the Combinatorial Activities of FoxH1 and Eomesodermin |
| PMC3103151__F1 | Intracellular pathway of folate metabolism with highlighted critical pathways of methotrexate (MTX) entry, effect and efflux |
| PMC3103318__F7 | Model pathway for genistein-induced ASAH1 transcription in MCF-7 cells |
| PMC3103347__F5 | Effect of SCGB3A2 on TGFB signaling pathway |
| PMC3103347__F7 | Schematic diagram for the SCGB3A2-induced inhibition of the TGFB signaling pathway |
| PMC3103499__F3 | Computational Identification of Transcriptional Regulators in Human Endotoxemia |
| PMC3103528__F5 | Inhibitory Actions of Anti-Müllerian Hormone (AMH) on Ovarian Primordial Follicle Assembly |
| PMC3103541__F8 | Long-Term Continuous Corticosterone Treatment Decreases VEGF Receptor-2 Expression in Frontal Cortex |
| PMC3103888__F1 | TIRs signaling pathway |
| PMC3103989__F1 | Endocrine, paracrine and autocrine regulation of the IGF-1R pathway and therapeutic strategies for its disruption |
| PMC3104011__F2 | miRNAs regulate DSB DDR through modulating the core protein components of various pathways |
| PMC3104012__F1 | Summary of the common pathways underlying neurodegenerative diseases and cancer that are mediated by miRNAs |
| PMC3104248__F1 | MTOR signaling pathway |
| PMC3104248__F2 | Genetic mutations of signaling molecules implicated in mTOR pathway (red Xs) |
| PMC3104248__F3 | Signaling molecules implicated in epilepsy (see the text for the detail) |
| PMC3104484__F5 | Interplay between Wnt, Nurr1 and En1 signaling in vitro and in vivo |
| PMC3104565__F1 | Simplified diagrams for agrin-induced signaling |
| PMC3104579__F1 | RhoA/ROCK I pathway and remodeling of microtubule network underlie the polarization and migration of HSPCs |
| PMC3104724__F2 | This figure outlines the role of KLF10 protein as a target and as a regulator of the TGFBeta-Smad 2,3 signaling pathway |
| PMC3104927__F6 | RHIM-dependent signaling |
| PMC3106121__F1 | Phosphodiesterases and Cardiac cGMP: Evolving Roles and Controversies |
| PMC3106141__F3 | Treating brain tumors with PDE4 Inhibitors |
| PMC3106338__F10 | INTERFERON-ALPHA MEDIATES THE DEVELOPMENT OF AUTOIMMUNITY BOTH BY DIRECT TISSUE TOXICITY AND THROUGH IMMUNE-CELL RECRUITMENT MECHANISMS |
| PMC3107100__F1 | Genetic alterations in glioblastoma signal transduction pathways (adapted from Parsons et al) |
| PMC3107200__F8 | Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss |
| PMC3107442__F5 | Transcripts (p < 0.05) involved in cell signaling |
| PMC3107509__F1 | Wnt signaling pathways |
| PMC3107984__F3 | Genetic analysis of biological pathway data through genomic randomization |
| PMC3108053__F1 | Fanconi anemia pathway and ICL repair: implications for cancer therapy |
| PMC3108097__F1 | Iron Homeostasis and the Inflammatory Response |
| PMC3108205__F4 | Delay in apoptosis at 9 hr |
| PMC3108467__F4 | IFN signaling pathway coded with identified proteins on day 7 postinfection |
| PMC3108474__F2 | Membrane type-MMPs regulate vascular cell signaling in cancer |
| PMC3108692__F1 | Mammalian target of rapamycin (mTOR) network |
| PMC3108840__F6 | Functional pathway analysis of glycoproteins overexpressed in PC3-N2 |
| PMC3108840__F7 | Functional pathway analysis of glycoproteins overexpressed in PC3-ML2 |
| PMC3109034__F6 | Working model for the role of the miR-29 family in TGFB2–mediated signaling |
| PMC3109102__F1 | Basic intracellular molecular pathways regulating MN survival during development |
| PMC3109223__F1 | MTOR signaling pathway |
| PMC3109273__F1 | Host cell death pathways targeted by L |
| PMC3109408__F2 | Simplified diagram of Kynurenine pathway: during neuroinflammation, 95% of the dietary tryptophan is metabolized along the KP within the brain |
| PMC3109490__F1 | Francisella tularensis tularensis targets the PI3K/Akt pathway at multiple levels |
| PMC3109492__F2 | Intestinal Effector T Cells in Health and Disease |
| PMC3109507__F1 | Choosing the right path: does DNA-PK help make the decision? |
| PMC3109512__F3 | Proposed role of CnPlc1 in pathogenicity-related signaling in C |
| PMC3109595__F5 | Gene regulatory network model for specification of the skeletogenic mesoderm lineage |
| PMC3109603__F7 | Comparative pathway networks of cyclic genes in mouse, chicken and zebrafish |
| PMC3109859__F6 | Finding Homes for Orphan Cytochrome P450s: CYP4V2 and CYP4F22 in Disease States |
| PMC3109860__F4 | CHK1 Inhibitors in Combination Chemotherapy |
| PMC3109866__F1 | Converging Pathways in Lifespan Regulation |
| PMC3109867__F1 | Insulin/iGF-1 signaling pathway is conserved across phylogeny |
| PMC3110060__F1 | MicroRegulators come of age in senescence |
| PMC3110099__F14 | Schematic diagram to show that knockdown of Akt1 leads to upregulation of Akt2 in response to oxidative stress and its regulation of oxidative-stress-induced apoptosis through three pathways |
| PMC3110186__F5 | Unraveling Molecular Signatures of Immunostimulatory Adjuvants in the Female Genital Tract through Systems Biology. |
| PMC3110626__F1 | Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome |
| PMC3110643__F7 | Cartoon representing CsA-mediated activation of TGF B1-dependent signaling leading to epithelial-mesenchymal transition in epidermoid carcinoma cells |
| PMC3110678__F3 | SAT and PT domains of NSAS in aflatoxin B1biosynthetic pathway |
| PMC3110682__F1 | Hypothesized mechanisms of physical activity in colon cancer |
| PMC3110730__F1 | Wnt signaling and regulation of Beta-catenin in tumorigenesis |
| PMC3110863__F4 | Regulation of MeCP2 expression by Bdnf |
| PMC3110886__F4 | Functional analyses of differentially expressed predicted targets of significantly altered microRNAs |
| PMC3110895__F4 | Modeled miRNA mediated pathways in the pathogenesis of lung fibrosis |
| PMC3110938__F2 | Genome-wide dissection of microRNA functions and co-targeting networks using gene-set signatures |
| PMC3111485__F5 | A Large Gene Network in Immature Erythroid Cells Is Controlled by the Myeloid and B Cell Transcriptional Regulator PU.1. |
| PMC3111669__F2 | BMP signaling and its blocking |
| PMC3111743__F6 | Correlation network among processes with activity modified by both OEA and KDS-5104 treatments is shown |
| PMC3111844__F1 | Overview of Androgen Metabolism Pathway Genes Considered, Including Candidate Genes and Genetic Variants Studied |
| PMC3112285__F2 | Pathway Crosstalk |
| PMC3112459__F1 | TGFB signalling pathway and breast cancer susceptibility |
| PMC3112527__F3 | Summary of the signaling pathway mediated by RET |
| PMC3113646__F6 | TGFBeta-and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR) |
| PMC3113675__F7 | Arginine methylation of G3BP1 regulates both Ctnnb1 mRNA and canonical Wnt/Beta-catenin signaling |
| PMC3113807__F5 | The Interplay between Protein L-Isoaspartyl Methyltransferase Activity and Insulin-Like Signaling to Extend Lifespan in Caenorhabditis elegans |
| PMC3114084__F2 | Titin domain arrangement in the cardiac sarcomere and connectivity within a mechanical signaling network |
| PMC3114309__F1 | The NFAT structure |
| PMC3114474__F1 | Mechanisms of Resistance to EGFR TKIs and Development of a New Generation of Drugs in Non-Small-Cell Lung Cancer. |
| PMC3114804__F10 | NKCC2 regulation |
| PMC3114846__F5 | Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases |
| PMC3115056__F1 | Regulation of neural process growth, elaboration and structural plasticity by NF-κB. |
| PMC3115327__F3 | Scheme of the signal transduction pathway in response to DNA damage |
| PMC3115623__F5 | Major intracellular signal transduction pathways for CRF1 and CRF2 receptors |
| PMC3115901__F4 | The core biochemical network of the ceramide/sphingosine-1-phosphate rheostat |
| PMC3116035__F3 | A) Schematic outline of mitochondrial and metabolic pathways connected to the PPP in hepatocytes |
| PMC3116046__F2 | Increased expression of DNA repair genes in invasive human pancreatic cancer cells |
| PMC3116111__F1 | Graphical representation of the candidate genes involved in the pharmacodynamics of doxorubicin in a stylized cancer cell |
| PMC3116122__F1 | PI3K pathway activates different processes that regulate proliferation, apoptosis and migration |
| PMC3116140__F2 | The core pathway of Notch signaling |
| PMC3116244__F1 | Signaling Pathways Altered in Hepatic Cancer Stem Cells |
| PMC3116400__F1 | DSBs in S and G2 phases of the cell cycle, collapsed replication forks, and daughter-strand gaps all require HR for their repair |
| PMC3116598__F1 | p21-activated kinases in Erbb2-positive breast cancer. |
| PMC3116645__F1 | Mammalian target of rapamycin (mTOR) signaling pathway |
| PMC3116873__F1 | Oncogenic CagA Promotes Gastric Cancer Risk via Activating ERK Signaling Pathways: A Nested Case-Control Study |
| PMC3117004__F2 | Updated most likely pathway for acylCer formation (November 2010) |
| PMC3117038__F1 | The roles of CARM1 and coactivator methylation in DNA damage signaling pathway |
| PMC3117317__F3 | NFKB signaling pathway |
| PMC3117391__F3 | Pathway for getifinib and docetaxel to generate the synergistic effects on KRT8 |
| PMC3117645__F9 | The miR-29 regulatory network in Zmpste24-/- progeroid mice |
| PMC3117856__F3 | MAPK signaling pathway |
| PMC3117879__F2 | Implications of Relationships between Human Diseases and Metabolic Subpathways |
| PMC3118222__F5 | Cycling through metabolism |
| PMC3118263__F4 | Pathway analysis links the differentially expressed gene signatures of the MED29 transduced Hs 700T and MIAPaCa-2 cells to a cellular network involved in cell cycle, cancer, and genetic disorder |
| PMC3118279__F2 | Ingenuity Pathway Analysis of epidermal genetic information retrieval-harvested melanoma specimens identifies overexpressed genes involved in melanocyte development and pigmentation |
| PMC3118351__F10 | Pathways by which BrdU impairs epithelial repair and induces persistent inflammation in the chronic NA injury model |
| PMC3118418__F1 | Which FGF ligands are involved in lens induction? |
| PMC3118436__F2 | Metabolic remodeling in cancer cells and regulation by signaling pathways involving oncogenes and tumor suppressor genes |
| PMC3118552__F7 | Activation of the Stress Protein Response Inhibits the STAT1 Signaling Pathway and iNOS function in Alveolar Macrophages: Role of Hsp90 and Hsp70 |
| PMC3118659__F13 | NAD+ biosynthesis and salvage pathways |
| PMC3118679__F1 | The networks of factors (genes product, hormones, and metabolites) potentially involved in the regulation of milk protein synthesis in lactating bovine mammary tissue |
| PMC3118679__F6 | Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 15 relative to -15 d postpartum |
| PMC3118679__F7 | Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 60 relative to -15 d postpartum |
| PMC3118679__F8 | Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 240 relative to -15 d postpartum |
| PMC3118704__F3 | Toll-like receptor-4 (TLR-4) signaling via MyD-88-dependent pathways |
| PMC3118759__F5 | Alteration to activity of the Akt/GSK3B signalling pathway can explain a number of the changes observed in microarray analysis of flies expressing rCAG, rCUG and rAUUCU repeats in the nervous system |
| PMC3119055__F4 | Gene Expression Profiling of Preovulatory Follicle in the Buffalo Cow: Effects of Increased IGF-I Concentration on Periovulatory Events |
| PMC3119055__F5 | Gene Expression Profiling of Preovulatory Follicle in the Buffalo Cow: Effects of Increased IGF-I Concentration on Periovulatory Events |
| PMC3119514__F2 | TNFA and TCR activation pathways |
| PMC3119514__F3 | IL-1 and TLR activation pathways |
| PMC3119514__F6 | RNA polymerase II transcription complex |
| PMC3119520__F7 | Predicted d-galactose network in Y. pestis |
| PMC3119709__F1 | Macrophages as a Battleground for Toxoplasma Pathogenesis |
| PMC3120109__F4 | Schematic illustrating that AMPH indirectly stimulates dopamine (DA), glutamate (glu) and BDNF (B) release and stimulation of D1 dopamine, glutamate, and TrkB receptors, respectively, in the striatum |
| PMC3120887__F5 | MicroRNA Expression Profiling Reveals MiRNA Families Regulating Specific Biological Pathways in Mouse Frontal Cortex and Hippocampus |
| PMC3120937__F1 | Signalling pathways in oesophageal adenocarcinoma |
| PMC3121188__F7 | ERK-dependent signalling during conditioning and extinction of fear |
| PMC3121446__F6 | P53 activation by NML-MYBBP1A in response to glucose limitation |
| PMC3121540__F4 | A gene network shows that mRNA levels of PDGFR and ECM-related genes are significantly correlated in human breast cancer |
| PMC3121598__F10 | The interplay between leptin, IGF-1 and AB42 |
| PMC3121749__F8 | Graded Nodal/Activin Signaling Titrates Conversion of Quantitative Phospho-Smad2 Levels into Qualitative Embryonic Stem Cell Fate Decisions |
| PMC3121779__F15 | Protective effects of OxPLs against acute lung injury and endothelial barrier dysfunction |
| PMC3121899__F3 | Cartoons of PAR-1-dependent signaling by APC and thrombin in endothelial cells when EPCR is either free or occupied by protein C |
| PMC3122057__F8 | Proposed schematic of the roles of NIK and SMG1 in sensitive versus resistant cells in response to SMC and TNFA treatment |
| PMC3122316__F1 | F igure 1.– |
| PMC3122626__F4 | Key cellular signaling cascades regulating morphogenesis in C |
| PMC3122626__F9 | The calcineurin signaling pathway in C |
| PMC3122959__F1 | Hedgehog signaling in skin cancers |
| PMC3123404__F2 | Functional consequences of bidirectional promoters |
| PMC3123543__F4 | Overlaid networks predicted by the PLS method and generated by IPA pathway designer |
| PMC3123739__F8 | DNA Repair Deficiency in Neurodegeneration |
| PMC3123876__F6 | Profiling experiments and pathway analysis |
| PMC3123905__F2 | Signal transduction pathways for itch |
| PMC3124048__F1 | Parallels in haematopoiesis between the Drosophila LG and mammalian bone marrow |
| PMC3124103__F1 | Transcription factor NFKB regulates the cellular response to inflammatory and oxidant stress, as well as stretch |
| PMC3124126__F1 | Molecular signaling cascades which normally control mTORC1 activity and may become dysregulated in B-cell lymphomas leading to aberrant mTORC1 signaling activation |
| PMC3124345__F2 | Schematic representation of the possible mechanisms leading to ovarian cysts in female patients with ORD |
| PMC3124359__F1 | Estrogenic effects on gp130 signaling |
| PMC3124472__F4 | Proteomic Analysis of Pathways Involved in Estrogen-Induced Growth and Apoptosis of Breast Cancer Cells |
| PMC3124513__F6 | Integrated Bio-Entity Network: A System for Biological Knowledge Discovery |
| PMC3124653__F1 | Systems pharmacology assessment of the 5-fluorouracil pathway |
| PMC3124653__F6 | Systems pharmacology assessment of the 5-fluorouracil pathway |
| PMC3124877__F1 | Pathway of alcoholic injury resulting in the direct production of oxidative stress and the LPS-TLR pathway that culminates in production of cytokines and other inflammatory processes that result in hepatitis of the liver |
| PMC3126020__F1 | Hedgehog signaling pathway in vertebrates |
| PMC3126020__F2 | Targeting the Hedgehog pathway in cancer |
| PMC3126106__F3 | Chemosensory processing in the taste - reward pathway |
| PMC3126159__F4 | Temporal regulation of apoptosis in SeV-infected cells by PI3K |
| PMC312639__F9 | Proposed model for RhoA signaling to the c-jun promoter |
| PMC3127069__F1 | The mTOR-signalling pathway from growth factor receptor through mTOR |
| PMC312710__F8 | RegA regulation by differential degradation |
| PMC3127159__F2 | TPO signaling pathway |
| PMC3127162__F8 | E3 ubiquitin ligase-dependent and E3 ligase-independent roles of Rad18 in tolerance of bulky DNA lesions (left) and replication-associated DSB (right) |
| PMC3127207__F2 | Luteolin Effects on Estrogen Signaling Pathway (ESP) Genes |
| PMC3127207__F4 | GenMAPP Diagram of Cell Cycle Pathway Genes Regulated by Luteolin in E2-Treated MCF-7 Cells |
| PMC3127250__F1 | Autophagy and the integrated stress response |
| PMC3127250__F6 | Autophagy and the integrated stress response |
| PMC312742__F9 | Role of E2F1 in the DNA damage response |
| PMC3128083__F9 | RIG-I Mediates Innate Immune Response in Mouse Neurons Following Japanese Encephalitis Virus Infection |
| PMC3128433__F3 | Complement cascade, hemolyisis, and eculizumab |
| PMC3128624__F6 | NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease |
| PMC3128635__F1 | RAS signaling to the PI3K pathway |
| PMC3128635__F2 | Crosstalk and feedback in ERK and PI3K signaling downstream of RAS |
| PMC3128772__F6 | Cell signaling between rNSCs and hMSCs in coculture |
| PMC3128904__F1 | Toll-like receptor (TLR) signaling pathway |
| PMC3128904__F2 | NOD-like receptor (NLR) family and inflammasome |
| PMC3129395__F4 | Molecular model of extranuclear functions of PV in promoting thyroid carcinogenesis via the integrin-FAK-cSrc signaling cascade |
| PMC3129465__F2 | Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies |
| PMC3129504__F2 | Ras/Raf/mitogen-activated protein kinase pathway |
| PMC3129516__F2 | SIRT3 and Cancer: Tumor Promoter or Suppressor? |
| PMC3130144__F6 | Molecular mechanism of autophagy with synthesis of cathepsin D |
| PMC3130335__F1 | MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells |
| PMC3130491__F4 | Schematic of leptin intracellular signaling through the STAT3 and PI3K-PDE3B-cAMP pathways in the hypothalamus |
| PMC3130501__F1 | Intrinsic and extrinsic apoptotic pathways |
| PMC3131053__F1 | Differential involvement of IKKB/NFKB signaling in neurons of the hypothalamic arcuate nucleus in the pathogenesis of obesity and hypertension |
| PMC3131055__F1 | Wolbachia-induced responses of specific cell types |
| PMC3131061__F1 | TIR and NFKB signaling pathways |
| PMC3131090__F1 | Negative regulation of the autophagy pathway |
| PMC3131135__F1 | Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection |
| PMC3131135__F2 | Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection |
| PMC3131147__F2 | Possible pathways to androgen independence and the involvement of ANG |
| PMC3131157__F6 | Manipulation of plant cell ubiquitin pathway by bacterial pathogens |
| PMC3131208__F2 | Cellular targets of the Tax viral oncoprotein |
| PMC3131208__F4 | NFKB signaling pathways |
| PMC3131451__F1 | The PI3K/mTOR signaling pathway highlighting the phosphorylation sites tested in our cellular and biochemical assays |
| PMC3131688__F1 | Autophagy in immunity and inflammation |
| PMC3131835__F3 | Sphingosine 1-phosphate (S1P) generation and ALI-associated single-nucleotide polymorphism (SNPs) in the S1P biosynthetic pathway |
| PMC3132106__F1 | Summary of the extracellular interactions between Wnts, Wnt receptors and Wnt regulatory proteins |
| PMC3132181__F1 | Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry |
| PMC3132181__F2 | Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry |
| PMC3132189__F4 | Proposed lipid metabolic pathways in Giardia |
| PMC3132554__F2 | Small-molecule inhibitors of the PI3K signaling network |
| PMC3132567__F8 | Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1A Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene Expression |
| PMC3132612__F2 | The major signal transduction pathway in the ER stress response |
| PMC3132641__F3 | Proposed mechanisms mediating the effect of the (pro)renin receptor (PRR) in metanephric kidney development |
| PMC3132733__F1 | Pathway-Based Association Analyses Identified TRAIL Pathway for Osteoporotic Fractures |
| PMC3132735__F7 | CCN2 Is Required for the TGFB Induced Activation of Smad1 - Erk1/2 Signaling Network |
| PMC3133224__F9 | Molecular interplay between FBXL2, its substrate CCTA, and CaM controls phosphatidylcholine (PC) synthesis |
| PMC3133232__F8 | Schematic model of Nrf2 regulation by Keap1 |
| PMC3133259__F1 | The CoA biosynthetic pathway |
| PMC3133356__F7 | Model showing the role for Bmi1 in the DNA damage response pathway |
| PMC3133616__F4 | Functional network of ion channels in T lymphocytes |
| PMC3133775__F2 | Second messengers and membrane trafficking direct and organize growth cone steering |
| PMC3133824__F1 | Cytonuclear signaling pathways in MSNs |
| PMC3133824__F2 | Mechanisms for import and export of proteins to and from the nucleus |
| PMC3133834__F1 | Activation of the Fas/FasL apoptotic pathway by interaction of Fas+ cells with FasL |
| PMC3133882__F4 | Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment |
| PMC3133912__F8 | Bhlhb5 and the Notch signaling pathway |
| PMC3133937__F1 | Concerted regulation of the WNT-DVL-GSK3B signaling pathway in NAc by chronic social defeat stress |
| PMC3134268__F1 | Schematic representation of the influence of photoperiod on deiodinase enzyme gene expression in the hypothalamus |
| PMC3134295__F1 | Apoptotic Process |
| PMC3134325__F1 | Action of ErbB receptor |
| PMC3134378__F2 | Regulation of HIF-1A by the MAPK pathway |
| PMC3134378__F3 | Regulation of HIF-1A by the PI3K pathway |
| PMC3134408__F1 | Proposed molecular pathways in arterial, venous and lymphatic specification in a developing embryo |
| PMC3134613__F6 | Specificity in neuronal activity-regulated gene transcription |
| PMC3134994__F1 | Schematic Illustration: TGF-beta signaling pathway |
| PMC3135180__F3 | Convergent stem cell regulatory networks control expression of key stem cell genes |
| PMC3135394__F3 | Localization of oxidant signaling |
| PMC3135641__F1 | Metabolic target genes of p53 |
| PMC3135645__F1 | Coordinated regulation of p53, target of rapamycin (TOR), and insulin/insulin-like growth factor 1 (IGF-1) pathways |
| PMC3135646__F1 | P53 pathway in development, cancer, and reprogramming |
| PMC3135880__F5 | Survival and proliferative effects of Dilong extract on RSC96 Schwann cell |
| PMC3136090__F5 | Signaling schematic representation: The postulated signaling pathway involved in this study |
| PMC3136091__F1 | Canonical and non-canonical NFKB signalling pathways |
| PMC3136221__F1 | “big picture” between DM2 and cancer |
| PMC3136489__F10 | Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood |
| PMC3136489__F11 | Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood |
| PMC3136489__F7 | Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood |
| PMC3136563__F12 | Working model for the role of USP4 in the negative regulation of TNFAlpha-induced TAK1 polyubiquitnation and NFKB activation |
| PMC3136693__F1 | Chemical heme biosynthesis pathway |
| PMC3136711__F2 | Qu on cell cycle |
| PMC3136877__F1 | mTOR signaling cascade in the pathogenesis and prevention of skin cancer |
| PMC3136902__F1 | IL-1RI signaling |
| PMC3136910__F2 | Proposed model of ATF2 regulation of Ha-Ras signaling |
| PMC3136937__F4 | Identification and Analysis of Signaling Networks Potentially Involved in Breast Carcinoma Metastasis to the Brain |
| PMC3137003__F2 | The insulin and leptin-melanocortin signaling pathway is responsible for maintaining energy and metabolic balance by controlling appetite |
| PMC3137012__F8 | Hypothesis of insulin signaling pathways associated with the regulation of CIDEA and CIDEC expression in human adipocytes |
| PMC3137145__F3 | Cigarette smoke exposure induces autophagy and apoptosis |
| PMC3137149__F1 | Simplified model of the tuberous sclerosis complex signaling pathway |
| PMC3137161__F1 | Roles of shati on dopamine uptake – the relationship shati and TNFA |
| PMC3137255__F2 | A simplified model for Hh signaling in mammalian cells |
| PMC3137639__F5 | Akt-RSK-S6-kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases |
| PMC3137710__F2 | Chemical 'Jekyll and Hyde's: Small-molecule inhibitors of developmental signaling pathways |
| PMC3137772__F2 | De novo biosynthesis of dolichol phosphate in human |
| PMC3137930__F8 | Analysis of p53 target genes in melanocytes treated with Nutlin-3 for 18 h |
| PMC3137974__F1 | Signal pathway activation by the main TLR and CLR receptors that detect Candida |
| PMC3138369__F1 | Signaling pathway for epidermal growth factor receptor (EGFR) |
| PMC3138532__F1 | HNSCC tumor microenvironment |
| PMC3138544__F1 | Targets and therapies for B-cell non-Hodgkin's lymphoma (B-NHL) within the context of the 10 hallmarks of cancer and overlapping oncogenic signaling pathways |
| PMC3138675__F2 | Molecular mechanisms in hereditary cancer |
| PMC3138766__F6 | JAK2 V617F-Dependent Upregulation of PU.1 Expression in the Peripheral Blood of Myeloproliferative Neoplasm Patients |
| PMC3139189__F1 | Intrinsic pathway of apoptosis |
| PMC3139189__F2 | B1/Fak/Src integrin signaling, cell survival, and suppression of anoikis |
| PMC3139189__F3 | Common pathway of anoikis induction |
| PMC3139433__F4 | Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes |
| PMC313952__F6 | Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals |
| PMC3139800__F1 | Regulation of endonuclease activity in human nucleotide excision repair |
| PMC3140053__F1 | Genetic Polymorphisms in Inflammation Pathway Genes and Prostate Cancer Risk |
| PMC3140140__F1 | Variation in the suppressive abilities of Wnt antagonists with respect to canonical and non-canonical Wnt signaling pathways |
| PMC3140170__F10 | Nicotine signal transduction pathways |
| PMC3140475__F5 | Proteomic Biomarkers for Acute Interstitial Lung Disease in Gefitinib-Treated Japanese Lung Cancer Patients |
| PMC3140648__F1 | D1 receptor signaling cascades in striatonigral/direct pathway neurons |
| PMC3140648__F3 | Roles of phosphodiesterases (PDEs) in the control of basal ganglia–thalamocortical circuitry |
| PMC3140692__F3 | Hypoxia regulates other critical pathways that impact tumor progression in a HIF-independent fashion |
| PMC3140915__F1 | Simplified schematic of the Wnt/Beta-catenin signaling pathway |
| PMC3140958__F6 | Protein interaction maps of the defined ratio clusters, (A) [G1_S]#3 and (B) [G1_S]#2 |
| PMC3141028__F4 | 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation |
| PMC3141076__F6 | Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression |
| PMC3141233__F7 | A model for the role of FANCD2 in Ad replication-dependent recombination |
| PMC3141288__F3 | Roles of NFKB-mediated inflammatory pathway in cellular transformation, cancer survival, proliferation, invasion, angiogenesis and metastasis |
| PMC3141289__F1 | Signaling pathway leading to signal transducer and activator of transcription (STAT)-3 activation (see text for definitions of abbreviations) |
| PMC314152__F7 | LMP1-induced canonical and noncanonical NFKB activation |
| PMC3141633__F3 | Genes identified in the TGF beta pathway |
| PMC3141878__F1 | TLR4 signaling cascade and evidence for modulation by neuropathic pain and opioids |
| PMC3141988__F6 | An E-cadherin-mediated Hippo signaling pathway |
| PMC3142070__F4 | Cause and metabolic consequences of fatty liver |
| PMC3142088__F7 | External stimuli (hyperglycemia, inflammation resulting from trauma, infection, or other injury) activate certain cells (e.g., endothelial cells, osteoblasts) to release RANKL |
| PMC3142564__F1 | Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer |
| PMC3142564__F3a | Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer |
| PMC3142627__F1 | Procession to Pediatric Bacteremia and Sepsis: A Series of Covert Operations and Failures in Diplomacy |
| PMC3142679__F1 | Virus reactivation: a panoramic view in human infections |
| PMC3142910__F5 | Schematic representation showing proposed role of TMPRSS6 regulation by the BMP6-SMAD signaling pathway and iron via ID1 |
| PMC314316__F1 | Schematic model indicating the presence of two potential insulin receptor–dependent signal transduction pathways |
| PMC3143377__F2 | Molecular Targeted Approaches in Mantle Cell lymphoma. |
| PMC3143377__F3 | Molecular Targeted Approaches in Mantle Cell lymphoma. |
| PMC3143653__F6 | Ingenuity pathway analysis of PKCAlpha-CT regulated, MEF2-targetted cardiac mRNAs |
| PMC3143721__F5 | Putative crosstalk between D1and TrkB receptors in striatal direct pathway neurons controlling PPD mRNA expression |
| PMC3143902__F1 | Inhibition of myostatin (MSTN) and activin signalling by the soluble activin type IIB receptor (ActRIB) |
| PMC3143906__F3 | Multiple factors and pathways affect insulin-like growth factor 1 (IGF1)-Akt signaling |
| PMC3144045__F1 | Signal pathway activation by different surface PRRs |
| PMC3144426__F1 | Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) |
| PMC3144530__F1 | Schematic overview of proposed G protein-coupled oestrogen receptor 1 (GPER1) signalling |
| PMC3144539__F5 | Proposed phase I and II biotransformation pathway for N-(4-hydroxyphenyl)retinamide (4-HPR) |
| PMC3145575__F3 | CSR pathways for primary non-HCC hepatocytes and HCC (Huh7) cell types |
| PMC3145576__F5 | Pathway analysis of proteins detected at elevated concentrations during time course analysis in lung following intratracheal instillation of 20 µg carbon nanoparticles (CNP) |
| PMC3145607__F5 | Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in G1-enriched MCF7 cell cultures |
| PMC3145607__F6 | Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in S-enriched MCF-7 cell cultures |
| PMC3145607__F7 | Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in G2/M-enriched MCF-7 cell cultures |
| PMC3145614__F1 | Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium |
| PMC3145765__F9 | Cardiomyocyte Specific Ablation of p53 Is Not Sufficient to Block Doxorubicin Induced Cardiac Fibrosis and Associated Cytoskeletal Changes |
| PMC3145778__F9 | Redox-Induced Src Kinase and Caveolin-1 Signaling in TGFB1-Initiated SMAD2/3 Activation and PAI-1 Expression. |
| PMC3146004__F4 | Pathway assignment of the important genes based on KEGG |
| PMC3146023__F3 | Human spermatogonial stem cells: a possible origin for spermatocytic seminoma |
| PMC3146054__F2 | Regulation of microsomal triglyceride transfer protein |
| PMC3146245__F2 | Genetic model for nuage assembly and piRNA pathway genes in mice |
| PMC3146511__F6 | Expression and Functional Roles of Angiopoietin-2 in Skeletal Muscles |
| PMC3146512__F2 | Genome Sequence of a Mesophilic Hydrogenotrophic Methanogen Methanocella paludicola, the First Cultivated Representative of the Order Methanocellales |
| PMC3146606__F2 | PARP function in base excision repair and consequences of PARP inhibition |
| PMC3146625__F1 | Schematic overview of the steroidogenic pathway |
| PMC3146784__F2 | TLR ligands and signalling |
| PMC3146967__F1 | ER activation of mGluRs is organized via caveolins into brain region specific functional microdomains |
| PMC3146975__F1 | Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1 |
| PMC3146975__F3 | Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1 |
| PMC3147278__F3 | Cross-talk between TLR4 and IL-1 signaling pathways |
| PMC3147301__F3 | Towards an understanding of the adjuvant action of aluminium |
| PMC3147552__F8 | Schematic overview of IDO induction by H |
| PMC3147800__F9 | Model showing the cooperative function of LMO7 and Rho in the activation of MRTFs |
| PMC3148026__F2 | Pathway alterations involved in the development of low-grade serous carcinoma |
| PMC3148231__F12 | MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus |
| PMC3148240__F1 | Simulating EGFR-ERK Signaling Control by Scaffold Proteins KSR and MP1 Reveals Differential Ligand-Sensitivity Co-Regulated by Cbl-CIN85 and Endophilin |
| PMC3148248__F5 | TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding |
| PMC3148288__F1 | ERM proteins are scaffolds for cAMP signaling pathways |
| PMC3148569__F6 | Perturbed TGFB/Smad and mitogen-activated protein kinase signalling pathways in Dupuytren's fibroblasts |
| PMC3148577__F1 | Metabolic networks of Corynebacterim glutamicum (a) and Brassica napus (b) corresponding to the experimental fluxes measured by [,]and []respectively |
| PMC3148577__F3 | A heterotrophic plant cells |
| PMC3148591__F2 | Major signaling pathways of IPC- and Ipost-mediated protection against cardiac cell death |
| PMC3148653__F3 | Network of TP53-regulated genes |
| PMC3148653__F4 | Network of HNF4A-regulated genes |
| PMC3148828__F4 | KEGG pathway: cell cycle |
| PMC3149005__F6 | Summary of the UPR pathway in rotavirus infected cells |
| PMC3149084__F2 | Single-run analysis of the yeast proteome by LC MS/MS |
| PMC3149098__F6 | GProX Pathway Analysis of the Cellular Response to EGF Stimulation |
| PMC3149150__F2 | Regulation of STEP phosphorylation |
| PMC3149170__F4 | Differentially expressed genes in the toll-like receptor signaling pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways |
| PMC3149315__F1 | Biosynthetic pathway of GSL and the CIRES procedure |
| PMC3149740__F5 | Mammals have two distinct but ultimately converging pathways to apoptosis |
| PMC3149747__F2 | Extensive feedback and feedforward loops between Ras signaling and miRNAs |
| PMC3149764__F3 | Emerging roles of JAK-STAT signaling pathways in adipocytes |
| PMC3149979__F1 | A representative immune response pathway that leads to the disruption of viral release from the plasma membrane |
| PMC3150418__F9 | NFKB signaling participates in both Receptor Activator of NFKB Ligand- (RANKL) and interleukin-4- (IL-4) induced macrophage fusion: Receptor cross-talk leads to alterations in NFKB pathways |
| PMC3151103__F9 | Schematic summary of a signaling pathway underlying IL-1Beta-induced dedifferentiation of primary cultured articular chondrocytes |
| PMC3151145__F1 | Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling |
| PMC3151419__F6 | Regulation of the mTOR signaling pathway by insulin and growth factors |
| PMC3151419__F7 | Regulation of mTOR pathway by Sestrins |
| PMC3151428__F3 | Suppression of anaerobic metabolism by p53 is mediated through multiple pathways |
| PMC3151497__F3 | MAPK signaling pathway |
| PMC3151543__F2 | Schematic depiction of how complement modulates T-cell immunity |
| PMC3152294__F1 | Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism |
| PMC3152494__F7 | The crosstalk between the NOTCH and AKT pathways at the molecular and cellular levels |
| PMC3152742__F3 | Proposed lithium's neuroprotective effects against cerebral ischemia |
| PMC3152870__F4 | Signalling pathway of type III interferons (IFNs) compared with type II and type I IFNs |
| PMC3152951__F1 | Interaction between HCV and Nuclear Receptor-mediated Pathways |
| PMC3152991__F6 | Insulin signaling pathway in adipocytes: showing potential sites of rhoifolin and cosmosiin interactions |
| PMC3153113__F7 | Hypoxia Induced Energy Stress Regulates mRNA Translation and Cell Growth |
| PMC3153165__F1 | Roles of the NFKB-mediated inflammatory pathway in cellular transformation and in cancer cell survival, proliferation, invasion, angiogenesis, and metastasis |
| PMC3153486__F5 | Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT1) Receptor Blockade |
| PMC3153880__F3 | Schematic representation of the effect of conventional treatment (Conv) and novel treatment (TKIs) on tumor behavior through the EGF-EGFR pathway |
| PMC3153965__F7 | Network representation of altered cellular functions during colonization of the mouse colon by A |
| PMC3154047__F1 | Activation of mammalian target of rapamycin complex 1 (mTORC1) |
| PMC3154190__F5 | Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics |
| PMC3154366__F4 | c-Myc regulates the rate limiting steps at the entry into glycolysis |
| PMC3154417__F2 | mTOR signaling pathway |
| PMC3154472__F1 | Identification and Phylogenetic Analysis of Heme Synthesis Genes in Trypanosomatids and Their Bacterial Endosymbionts |
| PMC3154612__F1 | Simplified diagram illustrating the mTOR signaling pathway |
| PMC3154715__F3 | Working model of relaxin sustained-vasodilatory response |
| PMC3154935__F4 | Influence of Stochastic Gene Expression on the Cell Survival Rheostat after Traumatic Brain Injury |
| PMC3155176__F4 | FRAM Is Characterized by Increased Signaling of the BRAF/MEK/ERK Pathway(A) IPA analysis led to the generation of a gene-interaction network of genes differentially expressed in patients |
| PMC3155178__F1 | Synthesis of Dihydrotestosterone via the Classic and Alternative (Backdoor) PathwaysThe classic pathway of steroidogenesis leading to dihydrotestosterone is shown on the left, and the alternative pathway is shown on the right |
| PMC3155287__F1 | Autophagy regulation |
| PMC3155297__F1 | General and organelle-specific stress response pathways influenced by the ageing process |
| PMC3155407__F1 | Murine model of the multiple actions to suppress immune surveillance of exosomes released from neoplastic cells |
| PMC3155635__F3 | Functional pathway analysis of the 12-gene genomic instability signature using Ingenuity Pathway Analysis |
| PMC3156249__F1 | B-Myb, Cancer, Senescence, and MicroRNAs |
| PMC3156300__F9 | Prolactin-Stimulated Activation of ERK1/2 Mitogen-Activated Protein Kinases is Controlled by PI3-Kinase/Rac/PAK Signaling Pathway in Breast Cancer Cells |
| PMC3156642__F1 | Crosstalk between the canonical and non-canonical transforming growth factor-beta1 (TGFB1) and myostatin pathways |
| PMC3156782__F2 | Wnt/Beta-catenin signaling pathway generated by Ingenuity Pathway Analysis (IPA) |
| PMC3156870__F1 | Resistance to RAF inhibitors in melanoma |
| PMC3156881__F12 | Interaction of the EGF and TGFB pathways in the control of proliferation in breast cancer (see also ) |
| PMC3157194__F4 | Interaction between MAPK signaling pathway-related genes and miRNAs |
| PMC3157228__F7 | Scheme for changes in the molecular pattern of inflammatory signaling, antigen processing, and presentation in attacked myofibers |
| PMC3157269__F3 | Sensing the HP-PRRSV infection by host cell |
| PMC3157296__F8 | Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth |
| PMC3157425__F4 | Apoptosis Induced by Piroxicam plus Cisplatin Combined Treatment Is Triggered by p21 in Mesothelioma |
| PMC3157546__F7 | The role of TAK1 signaling in bone metastasis |
| PMC3157706__F1 | Molecular pathways in LSCs of CML |
| PMC3157841__F1 | Expression Level Drives the Pattern of Selective Constraints along the Insulin/Tor Signal Transduction Pathway in Caenorhabditis |
| PMC3158097__F1 | Association Analysis of Canonical Wnt Signalling Genes in Diabetic Nephropathy |
| PMC3158334__F1 | Possible mechanisms of opioid receptor mediated influence of morphine on tumor growth |
| PMC3158608__F7 | Schematic representation summarizing the cell-type-dependent selectivity of CCK2 receptor signaling |
| PMC3158628__F1 | Unlinking of the Golgi ribbon during G2 inhibits the recruitment and activation of Aur-A at the centrosome trough a novel mechanism |
| PMC3158739__F1 | Ingenuity pathway analysis (IPA) of CDF driven pathway changes in BxPC-3 cells |
| PMC3158866__F1 | Toll-like receptor signaling pathway |
| PMC3159004__F2 | TLR-independent innate immune responses |
| PMC3159046__F6 | Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood |
| PMC3159098__F2 | Different RNA processing events in mammals |
| PMC3159104__F4 | Extrinsic signal pathways for regulating pluripotency during reprogramming |
| PMC3159106__F2 | TLR-mediated myeloid differentiation primary response gene 88 (MyD88)-dependent and TIR domain containing adaptor inducing interferon (IFN)B (TRIF)-dependent signaling pathways |
| PMC3159106__F3 | TLRs crosstalk with the phosphoinositide 3-kinase (PI3K) signaling pathway |
| PMC3159112__F5 | Ad signaling in endothelial cells |
| PMC3159114__F1 | Modulation of cellular reactive oxygen species (ROS) |
| PMC3159114__F10 | Role of GPx-1 in modulating apoptosis |
| PMC3159175__F1 | Multiple TYRO3-activated pathways signaling pathways converge with transcription or activation of MITF (reproduced from Mitra et al ()), an oncogenic transcription factor often dysregulated in malignant melanoma |
| PMC3159179__F4 | Methionine-Hcy metabolism |
| PMC3159301__F1 | Pathways involved in platelet hyperreactivity in DM patients and therapeutic targets |
| PMC3159521__F2 | Pre-B-cell-receptor signaling is regulated by a feed-back loop via Ikaros and Aiolos |
| PMC3159580__F3 | Not(ch) just development: Notch signalling in the adult brain |
| PMC3159954__F2 | Antiretroviral Therapy Down-regulates Innate Antiviral Response Genes in Patients with AIDS in Sub-Saharan Africa |
| PMC3159954__F3 | Antiretroviral Therapy Down-regulates Innate Antiviral Response Genes in Patients with AIDS in Sub-Saharan Africa |
| PMC3159971__F2 | Mathematical model of dual negative feedback regulation of JAK2-STAT5 signaling |
| PMC3159974__F4 | Predicted synthetic lethal gene pairs in TCA cycle (A), phosphatidylserine biosynthesis (B) and pentose-phosphate pathway (C) |
| PMC3160087__F7 | Model of the role of the Nodal and Cripto signaling pathways in mouse XEN cell differentiation |
| PMC3160099__F7 | Pathways that control the onset of adulthood and the terminal differentiation of specific cell lineages are conserved from C |
| PMC3160197__F1 | Crucial role of EGF signalling augments healthy lifespan in worms |
| PMC3160333__F2 | One Carbon Metabolism in SAR11 Pelagic Marine Bacteria |
| PMC3160745__F1 | PI-3K/Akt signaling pathway |
| PMC3160786__F1 | mTOR signaling pathwayu2003The scheme depicts mTOR signaling cascade in the regulation of energy and growth factor-dependent translation and autophagy |
| PMC3160786__F2 | Amino acids sensing of mTORC1u2003Rag-Ragulator-dependent mTORC1 activation in response to amino acid |
| PMC3160828__F1 | More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases |
| PMC3161051__F7 | Rad6B/Beta-catenin regulation in breast cancer cells with autocrine Wnt activity |
| PMC3161159__F1 | Retinoid metabolic pathway |
| PMC3161420__F1 | Regulation of apoptosis by the BCL-2 family |
| PMC3161675__F3 | Signal Transduction Involving the Dmp1 Transcription Factor and its Alteration in Human Cancer |
| PMC3161734__F3 | Predicting the Physiological Role of Circadian Metabolic Regulation in the Green Alga Chlamydomonas reinhardtii |
| PMC3161872__F1 | Summary of TNFR signalling |
| PMC3161973__F1 | Putative mogrosides biosynthesis pathway in Siraitia grosvenorii |
| PMC3162038__F2 | Biosynthetic pathway to validamycin A and characterization of VldB, VldE, and VldH |
| PMC3162305__F4 | Oncostatin M signaling pathway |
| PMC3162452__F7 | Schematic representation of intracellular pathways implicated in the regulation of cholesterol homeostasis and inflammatory response in human macrophages by IL-6 |
| PMC3162575__F12 | Wnt1/Fzd-1/Beta-catenin signaling as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk |
| PMC3163125__F1 | Complement system: the classical complement pathway involves a sequentially acting multistep cascade in which the complement components C1q, C1s, C1r, C4, C2, and C3 play important roles |
| PMC3163143__F2 | Schematic presentation of molecular changes associated with N-Myc amplification in neuroblastoma |
| PMC3163143__F3 | Genomic and non-genomic actions of all-trans retinoic acid (ATRA) |
| PMC3163259__F1 | Wnt/Beta-catenin signalling in the absence and presence of Wnt stimulus |
| PMC3163574__F2 | Identification and Visualization of CD8+ T Cell Mediated IFNG Signaling in Target Cells during an Antiviral Immune Response in the Brain |
| PMC316360__F6 | Interphase/S phase omission between the two meiotic divisions |
| PMC3163738__F3 | IFNA (type-I IFN) and IFN-λ (type-III IFN) signal through distinct receptor complexes, but activate the same intracellular signaling pathway |
| PMC3163765__F2 | Signal Transducer and Activator of Transcription 5a/b: Biomarker and Therapeutic Target in Prostate and Breast Cancer |
| PMC3163776__F2 | IRE1Alpha-XBP1 pathway in inflammation |
| PMC3163776__F3 | IRE1Alpha-XBP1 pathway in glucose homeostasis |
| PMC3163779__F1 | Thyroid hormone action is modulated by the deiodinases |
| PMC3163839__F2 | Sirt1 activity as it relates to AD etiology |
| PMC3163839__F3 | Progression of amyloidogenesis in parahippocampal region and hippocampal formation of mediotemporal lobe |
| PMC3163944__F7 | Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice |
| PMC316396__F7 | Axial and appendicular cartilage |
| PMC3164150__F1 | The insulin receptor (IR) with its two subtypes IR-A and IR-B, the insulin growth factor 1 receptor (IGF-IR) and the hybrid receptors (IGF-1R/IR-A and IGF-1R/IR-B) |
| PMC3164150__F2 | Insulin-like growth factor 1 receptor (IGF-1R) signaling pathway |
| PMC3164321__F1 | KEAP1 Cullin-3 E3-ubiquitin ligase complex and its roles in maintaining cellular levels of NRF2 and IKBKB |
| PMC3164457__F5 | Mi-2/NuRD complex depletion in germinal center B cells leads to alterations in chromatin, checkpoint activation, and delayed progression through S phase |
| PMC3164671__F5 | Genome-Wide Identification of Bcl11b Gene Targets Reveals Role in Brain-Derived Neurotrophic Factor Signaling |
| PMC3164688__F9 | Overview of the proposed mechanism by which microR-29b indirectly regulates the expression of PKR associated protein X (RAX) in the retinal neurons of the rat |
| PMC3164695__F7 | The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO |
| PMC3164721__F1 | Phospholipase C Isozymes Are Deregulated in Colorectal Cancer - Insights Gained from Gene Set Enrichment Analysis of the Transcriptome |
| PMC3164770__F5 | FLCN pathway |
| PMC3164983__F1 | mTOR inhibitors in renal cell carcinoma |
| PMC3165008__F1 | An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis |
| PMC3165056__F4 | Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity |
| PMC3165102__F1 | TGFB/SMAD/GLI2 signaling axis in cancer progression and metastasis |
| PMC316535__F6 | Genetic models for ptp-2 signaling during (A) oogenesis and (B) vulval development |
| PMC3165467__F6 | Results of Ingenuity pathway analysis |
| PMC3165779__F3 | Cellular PA-interaction networks |
| PMC3165799__F1 | Schematic diagram of the ER stress response |
| PMC3165904__F3 | Studies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase |
| PMC3166148__F3 | The citric acid cycle pathway (reprinted from KEGG []) |
| PMC3166203__F10 | Different ways to activate NFKB |
| PMC3166203__F12 | Upstream kinases and redox-sensitive phosphatases in NFKB activation |
| PMC3166203__F13 | Redoxosome formation in IL-1 signaling |
| PMC3166354__F1 | Cellular and Molecular Action of the Mitogenic Protein-Deamidating Toxin from Pasteurella multocida |
| PMC3166463__F1 | RIGI-like receptor pathway |
| PMC3166463__F3 | Innate immune signalling at the mitochondria |
| PMC3166557__F2 | Planar Cell Polarity Pathway - Coordinating morphogenetic cell behaviors with embryonic polarity |
| PMC3166778__F1 | PI3K signalling pathway: The phosphatidylinositol 3-kinase (PI3K) signalling pathway begins with PI3K activation by receptor tyrosine kinases after growth factors or insulin stimulation |
| PMC3167094__F1 | New Hormonal Therapies for Castration Resistant Prostate Cancer |
| PMC3167192__F1 | Molecular basics of tumor angiogenesis |
| PMC316759__F5 | Regulation of reproductive growth and metabolism by the DAF-2 insulin receptor-like signaling pathway |
| PMC316768__F1 | Model of somatic sex determination in C |
| PMC316782__F1 | Genetic pathways of sex determination in D |
| PMC3167888__F6 | Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages |
| PMC3168677__F2 | MicroRNAs in Rheumatoid Arthritis |
| PMC3168773__F2 | Functional relationship linking Crb proteins to the SWH pathway |
| PMC3169181__F2 | Crosstalk between host autophagy and viruses |
| PMC316921__F6 | Wnt signaling in the early C. elegans embryo |
| PMC3169412__F1 | Fatty-acid biosynthetic pathway for R |
| PMC3169508__F2 | An indirect interaction between the Axon Guidance and Insulin Signaling pathways in the network for the comparison between HF and LF diet at t = 0 |
| PMC3169508__F3 | Pathway interactions and detailed network visualization for the interactions with three apoptosis related pathways for the comparison between HF and LF diet at t = 0 |
| PMC3169542__F7 | Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD |
| PMC3169577__F1 | Evolution of the TGFB Signaling Pathway and Its Potential Role in the Ctenophore, Mnemiopsis leidyi |
| PMC316957__F9 | How ECSIT may participate in Toll/IL-1 signaling |
| PMC3169732__F6 | Schematic diagram illustrating the proposed signaling pathway involved in cigarette smoke extract-induced increase in expressions of inflammatory genes in airway smooth muscle cells |
| PMC3169997__F1 | Epithelial cell cycle arrest in G2/M and epigenetic changes in fibroblasts coordinately promote kidney fibrosis |
| PMC3170087__F2 | dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity |
| PMC3170087__F4 | dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity |
| PMC3170128__F5 | Innate and adaptive immune responses to cell death |
| PMC317013__F7 | Determinants of specificity in TGFB signal transduction |
| PMC317036__F5 | Model showing the possible relationship of dTOR with the insulin pathway |
| PMC3170448__F5 | Simply comparing and contrasting the expression patterns of perturbed genes was inadequate for deciphering the MAPK pathway response dynamics |
| PMC3170456__F1 | Autophagy in Cancer: Therapeutic Implications |
| PMC3170587__F2 | Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma. |
| PMC3170700__F1 | Activation of cellular responses during ER stress |
| PMC317073__F7 | Regulation of TNF-R1signaling pathways during apoptosis |
| PMC3170851__F2 | The Multifaceted Roles of Autophagy In Tumors--Implications For Breast Cancer |
| PMC3170890__F1 | IL-10 signal transduction and hypothesized treatment by dual gene therapy |
| PMC317132__F1 | Model of somatic sex determination in C |
| PMC3171365__F2 | Bayesian network fits for mutation data for cycle checkpoint II pathway using (a) Minimum Spanning Tree algorithm (maximum indegree of 1); (b) Bayesian Information Criterion (maximum indegree of 2) |
| PMC3171365__F3 | Bayesian network fits for wildtype data for cycle checkpoint II pathway using (a) Minimum Spanning Tree algorithm (maximum indegree of 1) |
| PMC3171509__F1 | This figure illustrates the core TSC-mTor pathway, as discussed in the text |
| PMC3171681__F1 | Roles and metabolism of glutathione |
| PMC3171706__F1 | G1/S transition and G1/S checkpoint induction |
| PMC3171706__F3 | G2/M transition and G2/M checkpoint induction |
| PMC3171751__F3 | Altered gene expression during pressure overload hypertrophy |
| PMC317204__F8 | Schematic diagram illustrating a model for the antagonistic roles of Dp110 and DPTEN in Drosophila growth control |
| PMC3172097__F1 | Autophagy pathway in plants |
| PMC3172101__F1 | New additions to the Hippo pathway in flies (a) and man (b) |
| PMC3172156__F2 | RLR signaling pathway showing RIG-I bound to ligand RNA and signaling downstream to IRF-3 and NF-kB to induce IFNA/B production from a virus-infected cell |
| PMC3172806__F7 | A model of pericyte-induced EC survival signaling |
| PMC3173057__F11 | Schematic view of the proposed HSP60-TLR4 signaling in response to myocardial ischemia |
| PMC3173146__F8 | Summary and working model |
| PMC317355__F3 | Wnt-signaling pathway |
| PMC3173728__F1 | In this figure we show the two main pathways to apoptosis, and their interaction through the molecule BID, since death receptors activate the intrinsic pathway by activating BID |
| PMC3173800__F2 | Two major pathways to caspase activation in vertebrates: the death receptor or extrinsic pathway, engaged by the indicated members of the TNF receptor family on the cell surface, and the Bcl-2-regulated mitochondrial or intrinsic pathway |
| PMC3173801__F1 | Many receptors modulate Wnt signalling |
| PMC3174148__F4 | Predictive Power Estimation Algorithm (PPEA) - A New Algorithm to Reduce Overfitting for Genomic Biomarker Discovery |
| PMC3174190__F2 | Autism-Associated Gene Expression in Peripheral Leucocytes Commonly Observed between Subjects with Autism and Healthy Women Having Autistic Children |
| PMC3174204__F6 | Conserved Regulation of p53 Network Dosage by MicroRNA-125b Occurs through Evolving miRNA-Target Gene Pairs |
| PMC3174208__F1 | Comprehensive Association Analysis of Homocysteine Metabolic Pathway Genes in Singaporean Chinese with Ischemic Stroke |
| PMC3174390__F1 | TGFB/Smads and crosstalk pathways in renal fibrosis and inflammation |
| PMC3174390__F4 | Inhibitory role of Smad7 in renal fibrosis and inflammation |
| PMC3174756__F5 | Ephrin and neurotrophin signaling pathways in primary neurons |
| PMC3174756__F6 | CDK5 (A) and actin (B) signaling pathway in primary neurons |
| PMC3174986__F3 | Plasmodium falciparum-Infected Erythrocytes and IL-12/IL-18 Induce Diverse Transcriptomes in Human NK Cells: IFNA/B Pathway versus TREM Signaling |
| PMC3175103__F4 | Dysregulated TRK Signalling is a Therapeutic Target in CYLD Defective Tumours |
| PMC3175149__F1 | IL-33 release and signaling via ST2L |
| PMC3175442__F2 | Map of pentose phosphate pathway (Genego Metacore) overlapped with quantile-normalized estimations of protein abundance |
| PMC3175442__F4 | Map of cytoskeleton remodeling pathway (Genego Metacore, fragment) overlapped with quantile-normalized estimations of protein abundance |
| PMC3175490__F2 | Intracellular signaling pathways integrate dopamine and glutamate signals |
| PMC3175541__F7 | NK2 homeobox 1 (NKX2-1)-Sam Pointed Domain Ets-like Factor (SPDEF)-associated gene network analyzed using Ingenuity Pathway Analysis |
| PMC3175556__F7 | Schematic diagrams of the signal transduction in TCDD-induced MUC5AC gene expression and the conventional AhR pathway in the activation of CYP1A1 expression |
| PMC3175563__F6 | Proposed mechanism of mechanical stress-induced activation of EGFR pathway in murine tracheal epithelial cells |
| PMC3175613__F3 | Proposed in vivo innate and adaptive immune responses to AAV vectors |
| PMC3175639__F2 | Clock-cancer connection in Non-Hodgkin's Lymphoma: a genetic association study and pathway analysis of the circadian gene Cryptochrome 2 |
| PMC3175712__F1 | (A-C) Schematics of Wnt signaling components in the absence of a Wnt signal (A), the presence of a Wnt signal (B), and the presence of a Wnt signal blocked by the displacement of Tcf7l2 by dnTcf7l2 (C) |
| PMC3175721__F6 | Models for context-dependent ICL repair during replication |
| PMC3175751__F2 | Schematic Overview of Nodal and Cripto-1 Signaling Pathways |
| PMC3176054__F5 | Proposed model of early pathologic events occurring in the lacrimal glands of C57BL/6.NOD-Aec1Aec2 male mice defined by changes in gene expression |
| PMC3176306__F1 | New strategies in Prostate Cancer: targeting lipogenic pathways and the energy sensor AMPK |
| PMC3176402__F4 | Zn and Zn transporters are indispensable for FcERI-mediated mast cell activation |
| PMC3176435__F2 | Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants |
| PMC3176897__F1 | Summary of fatty acid and glucose metabolism |
| PMC3177043__F2 | Different pathways of myostatin signalling |
| PMC3177269__F4 | Proposed model for a common symbiotic signaling pathway between actinorhizal plants and legumes |
| PMC3177306__F2 | The canonical vertebrate Wnt signaling pathway |
| PMC3177572__F6 | Schematic diagram summarizing the bidirectional role of PIAS1 in regulating JNK-dependent oxidative stress responses |
| PMC3177754__F3 | RIG-I Like Receptors and Their Signaling Crosstalk in the Regulation of Antiviral Immunity |
| PMC3177754__F4 | RIG-I Like Receptors and Their Signaling Crosstalk in the Regulation of Antiviral Immunity |
| PMC3178084__F2 | Runx2-deficient cells exhibit suppression of genes by insulin at multiple stages of the signaling pathway |
| PMC3178285__F5 | Proposed signaling of TNFA- and leptin-induced EL upregulation in primary placental ECs |
| PMC3178431__F6 | p63 signaling in cancer cells |
| PMC3178610__F5 | Determining Signalling Nodes for Apoptosis by a Genetic High-Throughput Screen |
| PMC3179275__F4a | Integrative computational biology for cancer research |
| PMC3179548__F2 | PE intoxication pathway |
| PMC3179812__F6 | Stem Cell Marker (Nanog) and Stat-3 Signaling Promote MicroRNA-21 Expression and Chemoresistance in Hyaluronan/CD44-activated Head and Neck Squamous Cell Carcinoma Cells |
| PMC3179879__F5 | Abrin (ABR)-triggered apoptosis |
| PMC3179880__F2 | Functional role of skeletal muscle-derived neurotrophic factors after exercise |
| PMC3179938__F3 | Top IPA generated network |
| PMC3179949__F6 | A schematic representation showing 17Beta-estradiol inhibition of uPA and MMP-9 expression, and cell motility via suppression of JNK1/2 pathway in human LoVo colon cancer cells |
| PMC3180046__F2 | NFKB signaling pathways |
| PMC3180062__F8 | Schematic Model of apoptotic signaling induced by targeting EphA2 gene by siRNA in MMC |
| PMC3180107__F1 | Intrinsic and extrinsic pathways of apoptosis |
| PMC3180107__F2 | Molecular mechanism of autophagy and its role in cell death and survival |
| PMC3180192__F2 | TGFB pathway genes in iMYC cells |
| PMC3180262__F8 | Hypothetical molecular signaling pathways of the expression of p27 by which moderate increase in the concentration of D-(+)-glucose down-regulates and deficiency of D-(+)-glucose or L-leucine up-regulates the expression of p27 |
| PMC3180377__F9 | Toll-Like Receptor 2 Pathway Regulates the Ppargc1a/b Metabolic Co-Activators in Mice with Staphylococcal aureus Sepsis |
| PMC3180440__F2 | Regulation of the early myogenic transcriptional program by the kinome |
| PMC3180440__F3 | Regulation of the late myogenic transcriptional program by the kinome |
| PMC3180573__F1 | Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke |
| PMC3180702__F6 | Transcriptional complexity of the mesenchymal-epithelial transition network |
| PMC3180925__F1 | Wnts signal through a "canonical" pathway involving Beta-catenin mediated transcriptional regulation (at left) and through "non-canonical" pathways involving calcium and Rac/JNK-mediated signaling (at right) |
| PMC3181038__F1 | Signaling the unfolded protein response: Three proximal sensors IRE1, PERK, and ATF6 regulate the UPR through their respective signaling cascades |
| PMC3181077__F1 | NFKB activation pathways and the impact of S-glutathionylation |
| PMC3181220__F3 | Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma. |
| PMC3181269__F1 | Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis and Signaling |
| PMC3181439__F1 | Jun N-terminal kinase signaling pathway |
| PMC3181488__F2 | Signal-receiving cell–modulation of developmental signalling by intracellular trafficking |
| PMC3181609__F2 | Amyloid precursor protein (APP) is processed either by Beta-secretase into a nonamyloidogenic pathway or by Beta- and Gamma-secretases to produce Beta-amyloid peptide (BA) |
| PMC3182268__F1 | Apoptotic pathway to cell death from the perspective of the Bcl-2 family of proteins.1, The intrinsic pathway is initiated by various signals, principally extracellular stimuli |
| PMC3182762__F1 | TLR signaling pathways |
| PMC3183286__F2 | The role of sphingosine kinase localization on substrate utilization and delivery of S1P to specific sites for secretion or loading of intracellular effectors |
| PMC3183400__F4 | New Insights into insulin resistance in the diabetic heart |
| PMC3183592__F1 | Normal hepatic methionine metabolism |
| PMC3184062__F9 | Scheme for poly(I:C)-induced apoptotic signaling pathway in high TLR3-expressing NB cells (left panel), but not low TLR3-expressing NB cells (right panel) |
| PMC3184251__F1 | Smac mimetics and TNFA: a dangerous liaison? |
| PMC3184252__F6 | Pathways of androgen biosynthesis |
| PMC3184987__F5 | Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component |
| PMC3185015__F9 | RSPO1/Beta-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary |
| PMC3185234__F1 | Enterohepatic circulation of the bile |
| PMC3185489__F1 | Diagram connecting the insulin pathway and fatty acid (FA) biosynthesis |
| PMC3185489__F2 | Some of the effects brought about by HCV on insulin signaling in hepatocytes |
| PMC3185489__F4 | The effects of HCV on steatosis development |
| PMC3185509__F1 | Activation of antiviral and proinflammatory responses during HSV infections |
| PMC3185509__F3 | Innate immune evasion mechanisms of HSV |
| PMC3185522__F3 | HCV induces the over-expression of PP2Ac via an ER stress response pathway |
| PMC3185527__F3 | Illustration of the type I IFN signaling pathway and its inhibition by the henipavirus P, V and W proteins |
| PMC3185539__F1 | Summary of NSP1 inhibition of the innate immune response pathway |
| PMC3185579__F3 | TLR-dependent and independent IFN-I induction, signaling and action |
| PMC3185585__F1 | Remodeling the cellular secretory pathway to support enterovirus replication |
| PMC3185594__F8 | Signaling pathways involved in JSRV Env-induced cell transformation |
| PMC3185611__F1 | PRRs involved in detecting flaviviruses |
| PMC3185699__F1 | Proposed signaling pathway to the actin cytoskeleton during HIV-1 entry in T lymphocytes |
| PMC3185727__F1 | Illustration of the endogenous RNAi pathway and therapeutic mimics |
| PMC3185763__F1 | Extrinsic (death receptor-mediated) and intrinsic (mitochondria-mediated) pathways that lead to apoptosis of HIV infected helper T cells |
| PMC3185772__F2 | Regulation of Blood-brain barrier permeability, entry of WNV in the brain and factors involved in the pathogenesis of WNV-induced neuroinvasisve disease |
| PMC3185776__F2 | Tax targets the NFKB pathway |
| PMC3185786__F1 | Survival pathways controlled by Tax |
| PMC3185810__F1 | Interplay between HTLV-1 and the type-I interferon (IFN-I) induction pathway |
| PMC3185810__F2 | Alteration of the IFN-I signaling pathway by HTLV-1 |
| PMC3186011__F1 | Cell surface and endosomal recognition of viruses by Toll-like receptors (TLRs) |
| PMC3186046__F1 | S1P receptor subtype-specific heterotrimeric G protein coupling and intracellular signaling mechanisms |
| PMC3186052__F6 | Inhibition of prostate cancer cell proliferation through statin use, and its impact on the HMG-CoA pathway |
| PMC3186711__F8 | A model of the role of TLR4 signaling pathways in regulating TNFA expression |
| PMC3186862__F1 | BAD pathway in genes associated with induced cisplatin-resistance |
| PMC3187166__F1 | Selected part of the central metabolism in C |
| PMC3187613__F5 | Signaling pathways that regulate mammalian autophagy |
| PMC3187694__F1 | Simplified model of autophagy |
| PMC3187860__F1 | Brain Arteriovenous Malformation Pathogenesis: A Response-to-Injury Paradigm |
| PMC3187864__F6 | Axon viability depends on coordinated endocytic trafficking and signaling |
| PMC3187934__F2 | Phosphorylation pathways adapted from KEGG (50)(51) |
| PMC3188357__F2 | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), is the major genotoxic heterocyclic amine generated from cooking meats at high temperatures |
| PMC3188430__F7 | miR-486 is an important regulator of PTEN/AKT signaling in normal and dystrophic muscle |
| PMC3188673__F5 | Vitamin D Metabolism and Function in the Skin |
| PMC3188682__F3 | TGFB1/SMAD3 signaling as an integrator of fibrotic mechanisms in the kidney |
| PMC3188704__F1 | Regulation of cell migration by signaling endosomes |
| PMC3188749__F3 | Simplified schematic presentation of the transcriptional hierarchy of essential factors and signaling pathways during endocrine specification of the pancreatic endoderm |
| PMC3188880__F2 | Stat3 interactions in glioma biology |
| PMC3188957__F4 | Highest confidence network of genes influenced by CLOCK knockdown |
| PMC3189169__F1 | Toll-like receptor (TLR) and type I interferon (IFN) signaling pathways |
| PMC3189824__F2 | Schematic model for the activation of NFKB signaling pathways |
| PMC3189826__F1 | p130Cas and p140Cap signalling involved in migration and invasion |
| PMC3189826__F7 | Signaling pathways leading to 3D invasion of ErbB2 transformed MCF10 cells over-expressing p130Cas |
| PMC3189939__F3 | CAFET Algorithm Reveals Wnt/PCP Signature in Lung Squamous Cell Carcinoma |
| PMC3190105__F1 | TLR-dependent and JAK/STAT-dependent signaling pathways in microglia |
| PMC3190192__F1 | PRL crosstalk with estrogen, progesterone, EGF/TGFA, and IGF-I |
| PMC3190874__F1 | Immunoglobulin E Receptor Signaling and Asthma. |
| PMC3190874__F2 | FcERI signaling pathway is negatively regulated by a number of cell surface and intracellular proteins that act at various points in the FcERI signaling network |
| PMC3190890__F7 | The signaling pathway of EpCAM complex proteins in the regulation and enhancement of OSKM-mediated pluripotency reprogramming |
| PMC3191034__F7 | Postulated model for GRTH negative autocrine molecular mechanism of regulation of androgen synthesis in Leydig cells |
| PMC3191051__F9 | Model for TGFB1-mediated signaling to the miR143/145 regulatory region |
| PMC3191464__F2 | Model depicting the pathway of TGFBeta-mediated Bim regulation and apoptosis |
| PMC3191732__F1 | Cyclooxygenase pathway of AA metabolism |
| PMC3191732__F11 | Hydrolytic metabolism of 2-AG and PG-Gs |
| PMC3191937__F3 | Local regulatory proteins that mediate some of the actions of TGFB in human myometrium and leiomyoma |
| PMC3192015__F1 | Mammalian target of rapamycin, Akt, and phosphatidylinositol 3-kinase signaling |
| PMC3192251__F2 | NPC and CF converge on multiple intracellular trafficking pathways |
| PMC3192435__F2 | Targeting the PI3K/Akt/mTOR pathway to treat lymphoma |
| PMC3192752__F5 | Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment |
| PMC3192838__F7 | Hepatitis C Virus Reveals a Novel Early Control in Acute Immune Response |
| PMC3192861__F10 | A schematic model of GC-mediated acute activation of NHE3 via SGK3 |
| PMC3192911__F2 | Therapeutic tol-DC in organ allotransplantationTol DC can be either recipient- or donor-derived (in the case of living-donor transplantation) |
| PMC3193228__F5 | Possible mechanisms of involvement of nuclear receptor LRH-1 in development of pancreatic cancer |
| PMC3193242__F7 | The cross-talk between IKK family members in the MyD88 signaling pathway |
| PMC3193279__F1 | VEGF Signaling Pathway within endothelial cells |
| PMC3193288__F1 | Innate immunity against RNA viruses in mammals |
| PMC3193400__F2 | Activation of NFKB and regulation of downstream transcriptional antioxidant and pro-oxidant targets |
| PMC3193402__F1 | Classical and alternative NFKB pathways in skeletal cells |
| PMC3193402__F2 | Crosstalk between RANKL- and TNF-induced NFKB signaling in OCs |
| PMC3193404__F1 | NFKB signaling pathways initiated by TLR4, TCR, TNF receptor 1, CD40 and genotoxic stress |
| PMC3193406__F1 | Canonical and non-canonical NFKB signaling pathways |
| PMC3193406__F2 | Positive and negative domains regulating p100 processing |
| PMC3193406__F3 | NIK stabilization as a mechanism of non-canonical NFKB signaling |
| PMC3193407__F1 | NFKB activation by the canonical pathway |
| PMC3193409__F4 | Expanding role of ubiquitination in protein kinase activation in diverse NFKB pathways |
| PMC3193426__F1 | DSB repair pathways and SUMO |
| PMC3193436__F1 | Model describing the proposed role of Rap1GAP in the control of GDNF-induced Ret signaling |
| PMC3193452__F1 | Regulated necrosis in the intestine of FADDIEC-KO mice |
| PMC3193469__F4 | Simplified cartoons illustrating the components of the cullin-RING E3 ligases (CRLs) |
| PMC3193469__F6 | Model of GA-induced DELLA protein degradation and the regulation of PIF protein function |
| PMC3193487__F1 | Schematic of crosstalk between TLR pathway and MHC molecules |
| PMC3193496__F1 | Two conserved branches of the canonical Wnt pathway |
| PMC3193496__F2 | HIPK2 and NLK/LIT-1 in Wnt signaling |
| PMC3193496__F4 | Context-dependent function of HIPK2 in Wnt signaling |
| PMC3193874__F2 | Caloric Restriction and Chronic Inflammatory Diseases |
| PMC3193940__F2 | An array of cellular stressors can perturb the folding environment in the endoplasmic reticulum (ER) leading to unfolded or misfolded protein |
| PMC3194179__F2 | Ingenuity Pathway Analysis identified ERK as the Top network signaling Hub where the shaded shapes indicate the candidate genes from the present study |
| PMC3194179__F3 | Ingenuity Pathway Analysis identified MapK as second Top network signaling Hub where the shaded shapes indicate the candidate genes from current study |
| PMC3194179__F4 | Ingenuity Pathway Analysis identified NFKB as the Top Network signaling Hub where the shaded shapes indicate the candidate genes from the present study |
| PMC3194221__F2 | 1,25(OH)2D3 intracellular signalling pathway |
| PMC3194983__F1 | Inhibition of the type I interferon (IFN) induction and signaling pathways by viral proteins of KSHV |
| PMC3195192__F2 | VEGF-VEGFR signaling in lymphangiogenesis |
| PMC3195227__F1 | A schematic diagram of the kynurenine pathway |
| PMC3195649__F2 | Targeted therapies for breast cancer |
| PMC3195753__F3 | Comparative analysis of plastid transcriptomes in cucumber |
| PMC3196058__F2 | Dynamic Role of Beta-Catenin in Synaptic Plasticity |
| PMC3196095__F6 | Proposed model |
| PMC3196116__F10 | Proposed model shows the requirement of the IL-4RAlpha-Jak2-mediated signaling pathway for IL-13-induced M2 gene expression in human monocytes/macrophages |
| PMC3196148__F9 | Working model for the ATF4-dependent and c-JUN-dependent AA signaling pathways |
| PMC3196210__F2 | Relationships of different neurons in the striatum and neurotransmitter signaling involved in interval timing |
| PMC3196283__F1 | BER pathways BER is initiated by a damage specific DNA glycosylase and APE1 that excise the damaged base and incise the arising abasic site, respectively generating a DNA single strand break with a 5'-sugar phosphate |
| PMC3196377__F6 | Regulator of G Protein Signaling 6 (RGS6) Mediates Doxorubicin-induced ATM and p53 Activation by a Reactive Oxygen Species (ROS)-dependent Mechanism |
| PMC3196381__F1 | Proposed anti-WNV signaling pathways in mosquitoes |
| PMC3196718__F4 | Network of upregulated genes in C2C12 cells treated with rhBMP2 and rhBMP7 using the STRING 9.0 pathway analyzer |
| PMC3196743__F2 | The Contribution of Vitamin A to Autocrine Regulation of Fat Depots |
| PMC3196888__F8 | A model showing the overlapping functions of MMR and FA proteins in ICL and MMR |
| PMC3197200__F2 | Intracellular signaling pathways regulating growth |
| PMC3197364__F6 | Hypothesized mechanisms for sphingolipids in cardioprotective signaling in response to ischemia or hypoxia |
| PMC3197531__F12 | Beta-Adrenergic Receptor-PI3K Signaling Crosstalk in Mouse Heart: Elucidation of Immediate Downstream Signaling Cascades |
| PMC3197649__F3 | Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes |
| PMC3197649__F6 | Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes |
| PMC3197858__F1 | Fatty acid synthase as a potential therapeutic target in cancer |
| PMC3198061__F3 | In individuals with high macrophage aggregation around dead adipocytes as CLS, activation stimuli such as IL-1, lipopolysaccharide (LPS) and lipopolysaccharide binding protein (LBP), and TNFA bind to their appropriate membrane receptors |
| PMC3198763__F2 | MTORC1 pathway controls cellular metabolism |
| PMC3198803__F5 | CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae |
| PMC3198803__F7 | CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae |
| PMC3198893__F4 | One of the networks of genes commonly induced in both dendritic cells and macrophages when infected by bacteria, in both human and mouse |
| PMC3198893__F5 | One of the networks of genes strongly induced in dendritic cells but less so, unchanged, or suppressed in macrophages |
| PMC3198933__F1 | Toll-like receptor (TLR) signaling |
| PMC3199248__F1 | TLR induction of inflammation by parasitic infection |
| PMC3199279__F2 | Metabolic interactions between folates and vitamins B12, B6, and B2 |
| PMC3199545__F1 | Schematic diagram illustrating some of the major abnormalities related to sensitized D1R-signaling and associated to LID |
| PMC3199787__F4 | Graphical representation of the IL-6 signaling pathway reveals significant gene expression changes following sarin-induced seizure |
| PMC3199809__F1 | The TGFB signaling pathway |
| PMC3199966__F1 | Schematic biosynthetic pathways for the major phospholipid (Kennedy Pathway) and sphingolipid classes biosynthesized in mammalian cells and observed in MALDI IMS of mammalian tissues |
| PMC3200079__F3 | Homeostatic and leukemic expression of receptors, signaling proteins, and transcription factors along the B cell pathway |
| PMC3200456__F1 | Toxoplasma gondii effectors are master regulators of the inflammatory response |
| PMC3200485__F2 | RGS14 at the interface of hippocampal signaling and synaptic plasticity |
| PMC3201689__F1 | Diagram illustrating the DNA base excision repair (BER) pathway |
| PMC3201744__F1 | MiR-21, miR-126, and miR-148a directly or indirectly regulate DNMT1 in SLE CD4+ T cells.A |
| PMC3201973__F9 | Toll-like Receptor 3 Regulates Neural Stem Cell Proliferation by Modulating the Sonic Hedgehog Pathway |
| PMC3202104__F2 | EBV infection impacts on cell death and survival pathways in GC B cells |
| PMC3202302__F1 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202302__F2 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202302__F4 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202302__F5 | Signaling by the TNFR superfamily in B-cell biology and disease |
| PMC3202514__F1 | Maturational changes in fatty acid and carbohydrate metabolism gene expression |
| PMC3202623__F7 | The Potential Roles of Fumarate as an OncometaboliteThe KEAP1 protein is part of an E3 ubiquitin ligase, which under normal physiological conditions targets NRF2 for polyubiquitination and subsequent degradation () |
| PMC3202828__F5 | Cif hijacks several and various signaling pathways by inhibiting the ubiquitin ligase activity of CRL |
| PMC3202852__F4 | Gi/o protein-dependent and -independent effects of PTX |
| PMC3202860__F2 | Proposed trichothecene biosynthetic pathway in Fusarium |
| PMC3202988__F1 | Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells |
| PMC3203219__F1 | Costimulatory pathways relevant in transplantation |
| PMC3203325__F2 | XPC: Implications in cancer and oxidative DNA damage |
| PMC3203674__F1 | Coronin 2A-dependent LXR transrepression pathway in macrophages |
| PMC3203685__F1 | Summary of the Proceedings from the 10th Annual Meeting of Molecularly Targeted Therapy in NSCLC |
| PMC3203691__F3 | CXCL10/IP-10 in Infectious Diseases Pathogenesis and Potential Therapeutic Implications |
| PMC3203699__F8 | TRAF3-mediated positive and negative regulation of IFN signaling |
| PMC3203793__F1 | Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. |
| PMC3203793__F6 | Molecular modulation of peripheral myelination by the Sirt2/Par-3/aPKC pathway |
| PMC3204078__F5 | SHP-1 activation and modulation on ghrelin signaling to Akt |
| PMC3204314__F7 | Signalling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis |
| PMC3204462__F1 | TRAIL signaling pathway and regulatory proteins |
| PMC3204848__F13 | Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane |
| PMC3205057__F5 | Effect of miR-300 on TGFB signaling pathway |
| PMC3205057__F6 | Influence of miR-300 on apoptosis pathway |
| PMC3205057__F8 | Effect of miRNAs on cell cycle, proliferation, and differentiation |
| PMC3205232__F1 | A brief survey of mRNA surveillance |
| PMC3205276__F1 | Biosynthetic pathway of sphingolipids consisting of free long chain bases (top row), which are N-acylated by several CerS enzymes to form dihydroceramides (upper row of octagons) |
| PMC3205325__F2 | Canonical TGFB signaling; Smad-dependent pathway downstream of TGFB receptors |
| PMC3205612__F1 | Interplay between autophagy and intracellular pathogens |
| PMC3205681__F2 | Post-translational modifications (PTMs) of transcription factors |
| PMC3205804__F2 | From a physiological point of view, exfoliated epithelial cells resulting from nutritional induction or mild stress are in anoikis by activating a survival mechanism partly using the molecular paths of macroautophagy |
| PMC3205852__F10 | Schematic illustrating the potential role of integrin B3 (ITGB3) in ROS-induced migration and invasion of colorectal cancer cells |
| PMC3206016__F9 | Putting into Practice Domain-Linear Motif Interaction Predictions for Exploration of Protein Networks |
| PMC3206070__F2 | Temporal Order of Genetic and Pathway Alterations in Tumorigenesis |
| PMC3206090__F2 | Convergent pathogenic pathways in Alzheimer's and Huntington disease: Shared targets for drug development |
| PMC3206090__F5 | Convergent pathogenic pathways in Alzheimer's and Huntington disease: Shared targets for drug development |
| PMC3206195__F3 | Fear Conditioning, Synaptic Plasticity, and the Amygdala: Implications for Posttraumatic Stress Disorder |
| PMC3206202__F10 | Expression Profiling Reveals Differential Gene Induction Underlying Specific and Non-Specific Memory for Pheromones in Mice |
| PMC3206202__F9 | Expression Profiling Reveals Differential Gene Induction Underlying Specific and Non-Specific Memory for Pheromones in Mice |
| PMC3206266__F3 | Androgen biosynthesis in the prostate |
| PMC3206369__F1 | Primary phosphatases function as tumor suppressors and their signaling pathways |
| PMC3206384__F1 | Schematic diagram depicting the possible pathways in which NO modulates collagen type I gene expression to affect fibrosis |
| PMC3207123__F1 | A view of CD133 expression as it relates to variety of normal tissue and cancer stem cells |
| PMC3207219__F1 | ROCK signaling pathway with focus on survival and regeneration |
| PMC3207473__F7 | Model: TTP transition from "hypo- to hypermodified" determines its functional switch |
| PMC3208056__F4 | Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/Beta-catenin/cyclin D1 signaling pathway in rats |
| PMC3208628__F5 | Integrated Transcriptome and Binding Sites Analysis Implicates E2F in the Regulation of Self-Renewal in Human Pluripotent Stem Cells |
| PMC3208682__F1 | Expression patterns of the TLR signaling pathway in CLL |
| PMC3209136__F2 | Biosynthetic pathway for UA and flocculosin |
| PMC3209254__F9 | The multiple mechanisms by which Sox2 regulates the osteoblast lineage |
| PMC3209293__F6 | IA30-infected pigs fail to induce immune response genes associated with pattern recognition of viruses and cytokine and immune cell responses in the lung |
| PMC3209350__F1 | Synthesis, utilization, and regeneration of glutathione and regulation of mTORC1 activity |
| PMC3209384__F8 | Schematic showing the mechanism(s) of activation of the NLRP3 inflammasome and NFKB signaling pathways by vMyxM013-KO virus infection in human monocytic cell line THP-1 |
| PMC3209670__F3 | mTOR signaling pathway affected by pollen feeding or varroa parasitism |
| PMC3209802__F1 | Assembly of checkpoint and repair machineries at DNA damage sites |
| PMC3210079__F8 | Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells |
| PMC3210456__F7 | Cyclin D1 action and degradation |
| PMC3210466__F1 | MTOR signaling pathways |
| PMC3210925__F5a | Mapping photoautotrophic metabolism with isotopically nonstationary 13C flux analysis |
| PMC3212439__F5 | Immunoproteasomes Regulate Lps-Induced Trif/Tram Signaling Pathway in Murine Macrophages |
| PMC3212543__F11 | Loss of Sphingosine Kinase 1/S1P Signaling Impairs Cell Growth and Survival of Neurons and Progenitor Cells in the Developing Sensory Ganglia |
| PMC3213081__F1 | The P2X7 Receptor in Infectious Diseases |
| PMC3213160__F3 | Capture of MicroRNA-Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling |
| PMC3213224__F3 | Possible mechanism of reciprocal enhancement between innate and adaptive immunity, through NF-kB and STAT-1/IRF-1 pathway |
| PMC3213329__F3 | Ingenuity pathway analysis of phosphatidylinositol 3-kinase (PI3K) signaling pathway affected by angiotensin II |
| PMC3213398__F7 | Working Model for the Late-Acting Function of NFU1 in Mitochondrial Fe-S Protein BiogenesisThe findings of this work suggest a late-acting function of NFU1 in the pathway of Fe-S (red and yellow circles) protein maturation |
| PMC3213687__F2 | Appearance frequencies of genes in the mTOR signaling pathway |
| PMC3213765__F12 | Schematic of the sonic hedgehog signaling pathway |
| PMC3213765__F13 | The sonic hedgehog signaling pathway in the primary cilium |
| PMC3213765__F17 | Wnt signaling pathway |
| PMC3213765__F20 | Shh and BMP signaling |
| PMC3213966__F3 | Regulation of cardiac hypertrophy by AKAP complexes |
| PMC3214144__F1 | HCMV promotes GBM pathogenesis |
| PMC3214149__F3 | Schematic overview of CagL and CagA-mediated signal transduction pathways involved in H |
| PMC3214273__F1 | Pathogenic microbes and community service through manipulation of innate immunity |
| PMC321431__F10 | Cascade of transcription factors that induce stress gene expression in response to eIF2A phosphorylation |
| PMC321455__F9 | A model depicting the relationship between the p19Arf-p53 tumor suppressor pathway and the Rho GTPase signaling module in the regulation of cell proliferation and transformation |
| PMC321458__F8 | Model of the role of RNase MRP in cell cycle control |
| PMC3215220__F5 | SPION-induced toxicity at cellular level |
| PMC3215281__F7 | Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease |
| PMC3215729__F1 | Rv2607 from Mycobacterium tuberculosis Is a Pyridoxine 5'-Phosphate Oxidase with Unusual Substrate Specificity |
| PMC3215775__F1 | Molecular mechanisms through the Epidermal Growth Factor Receptor pathway |
| PMC3215886__F2 | The "inhibitory" pathway of WNK4 |
| PMC3215943__F3 | MOLECULAR MECHANISMS OF FEAR LEARNING AND MEMORY |
| PMC3215943__F4 | MOLECULAR MECHANISMS OF FEAR LEARNING AND MEMORY |
| PMC321618__F7 | Statins and bacterial infection: model illustrating the effects of statins on S. enterica serovar Typhimurium infection |
| PMC3216277__F1 | Within the intestinal lumen, the micellar solubilization of sterols facilitates movement through the diffusion barrier overlying the surface of the absorptive cells |
| PMC3216277__F5 | Pathways underlying the absorption of cholesterol from the intestinal lumen and its delivery to the liver |
| PMC3216306__F1 | Downregulation of macrophages signalling by Leishmania infection |
| PMC3216388__F1 | Metabolism of sulfur containing amino acids |
| PMC3216677__F1 | Proposed estrogen receptor (ER)-activated signaling pathways involved in vasodilation |
| PMC3216694__F1 | Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors |
| PMC3216974__F7 | S6K1 and 4E-BP1 Are Independent Regulated and Control Cellular Growth in Bladder Cancer |
| PMC3217176__F3 | Targeting the PI3K/AKT/mTOR pathway |
| PMC3217183__F5 | Signaling components of the RAS/MAPK pathway found to harbor activating mutations in various types of nevi and melanoma |
| PMC3217196__F1 | MicroRNAs in Mutagenesis, Genomic Instability and DNA Repair |
| PMC3217209__F1 | Insulin Resistance, Hyperglycemia, and Atherosclerosis |
| PMC321741__F1 | Signaling pathways for TLR-3 and TLR-4 |
| PMC3218055__F3 | Proteomic Signatures of Human Oral Epithelial Cells in HIV-Infected Subjects |
| PMC3218540__F2 | Folate metabolic pathway |
| PMC3218720__F2 | Receptors that sense danger signals released from neighboring injured retinal pigment epithelial (RPE) cells |
| PMC3218743__F2 | Inflammation in the gouty joint |
| PMC3218875__F2 | Noncanonical NFKB signalling |
| PMC3218884__F4 | Signalling network of proteins identified as major targets of autoantibodies in patients with unidentified ANA |
| PMC3218904__F1 | Network pathway analysis of up-regulated genes in the gene category immune response |
| PMC3218904__F2 | Network pathway analysis of down-regulated genes in the gene category mitotic cell cycle |
| PMC3218922__F6 | Pathway generated by ingenuity pathway analysis with proteins identified as specific target antigens |
| PMC3218933__F2 | Cross-talk among embryonic signaling pathways and experimental inhibitors |
| PMC3218933__F3 | Embryonic pathway signaling leads to induction of epithelial-to-mesenchymal transition |
| PMC3219052__F1 | SRC-3ÃŽâ€4 isoform acts a signaling adaptor for EGF-dependent cancer cell migration and invasion |
| PMC3219092__F3 | Nox regulation of the PI3K/AKT pathway |
| PMC3219211__F1 | Small-molecule inhibitors in the ubiquitin-proteasome system (UPS) |
| PMC3219404__F1 | Putative involvement of the receptor for advanced glycation endproducts (RAGE) during infection |
| PMC3219632__F11 | Suppressor of Cytokine Signalling-6 Promotes Neurite Outgrowth via JAK2/STAT5-Mediated Signalling Pathway, Involving Negative Feedback Inhibition |
| PMC3219972__F3 | Effect of carbon exchange and reversibility constraints |
| PMC3220493__F6 | Schematic model in which FGF2 stimulation of osteoblast differentiation is partially through modulation of the Wnt/Beta-catenin pathway |
| PMC3221387__F1 | Impact of miR-215 on cell proliferation, cell cycle, chemoresistance, and EMT |
| PMC3221598__F3 | Protease Regulation: The Yin and Yang of neural development and disease |
| PMC3221684__F8 | Insulin Receptor-Mediated Signaling via Phospholipase CG Regulates Growth and Differentiation in Drosophila |
| PMC3221733__F3 | Drosophila melanogaster as a model system for human brain cancers |
| PMC3221743__F5 | Working model describing how in HIV+ macrophages constitutively activated PI3K elicits blunting of lipid A-induced increases in TNFA release through sustained mTOR activation |
| PMC3222593__F2 | Pathway Studio® (Ariadne Genomics) was used to identify known relationships among human homologues of the genes identified as differentially regulated by ANOVA |
| PMC3222852__F1 | GSK3 plays pivotal roles in the establishment and maintenance of neuronal polarization |
| PMC3222852__F2 | GSK3 is a key regulator of axon growth and branching |
| PMC3223033__F6 | Schematic illustration of the main metabolic pathways based on the proteins identified in the citrus pulp chromoplasts |
| PMC3223252__F7 | A refined model shows MEHP-decreased TIMP2 expression in Sertoli cells is mediated by the inactivation of CEBPA and the activation of MYC and is dependent upon the FSH-stimulated cAMP signaling pathway |
| PMC3223722__F1 | Glycogen synthase kinase 3 modulates the function of key signaling proteins in the wnt pathway |
| PMC3223826__F5 | JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors |
| PMC3224136__F7 | Schematic pathway showing a possible role for STC2 in affecting the PERK signalling pathway |
| PMC3224200__F1 | Contribution of chemoattractant GPCRs to glioma stem-like cell mediated tumorigenesis, invasion and angiogenesis express various GPCRs |
| PMC3224393__F1 | Reaction scheme for EGFR signal transduction pathway in H1299 cells |
| PMC3224437__F4 | Fatty acid biosynthesis model and pathway distance calculation method |
| PMC3224542__F1 | Genes related with the tau protein phosphatase-2A (PP2A) pathway |
| PMC3224806__F1 | Deciphering the role of Th17 cells in human disease |
| PMC3225017__F2 | c-MET signaling adaptors and mediators |
| PMC3225017__F3 | c-MET transactivation |
| PMC3225028__F2 | WT1/EGR1-mediated Control of STIM1 Expression and Function in Cancer Cells |
| PMC3225503__F6 | Pathway model based on vision related TMT-associated gene expression changes indicating a possible mechanism for TMT elicited neurobehavioral changes |
| PMC3225910__F1 | Signaling network connecting Rheb and AMPK |
| PMC3225948__F7 | Three arms of the unfolded protein response stress-responsive signaling pathway |
| PMC3226036__F5 | A schematic representation of the two classical apoptotic pathways in mammalian cells |
| PMC3226194__F7 | An integrated pathway model involving FOXA1 in breast cancer |
| PMC3226315__F1 | Recent focus in JMML has concentrated on using the information gained from knowledge of these molecular defects in order to design targeted drug therapy |
| PMC3226388__F3 | Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway |
| PMC3226689__F7 | Hole-in-One Mutant Phenotypes Link EGFR/ERK Signaling to Epithelial Tissue Repair in Drosophila |
| PMC3227097__F6 | Network of core pathways that mediate commitment of cells to the division cycle |
| PMC3227454__F2 | Epidermal growth factor and aging: A signaling molecule reveals a new eye opening function |
| PMC3227570__F9 | Divergent BMP signaling pathways controlling transcriptional and cytoskeletal responses |
| PMC3227667__F3 | Genetic Signature of Spina Bifida Risk from Pathway-Informed Comprehensive Gene-Variant Analysis |
| PMC3227781__F2 | Genomic and nongenomic vascular effects of estrogen |
| PMC3227927__F1 | Signaling pathways and effects of EGFR |
| PMC3227936__F1 | EGFR signaling pathway |
| PMC3227953__F1 | PI3K/Akt/mTOR pathway signaling in tumor and vascular endothelial cells |
| PMC3227962__F5 | Targets for intervention in the TGFB1 pathway (partial list) [, , ] |
| PMC3228010__F1 | Signaling pathways of sunitinib and sorafenib cardiotoxicity |
| PMC3228119__F1 | PI3K/AKT/mTOR signaling network regulates cell survival, proliferation, migration, metabolism, and apoptosis, integrating the growth factor signaling pathway, nutrient status, and other oncogenic pathways |
| PMC3228218__F1 | HCG/MET signaling pathway [] |
| PMC3228224__F1 | Pathways involved in mTOR signaling.Abbreviations: mTOR, mammalian target of rapamycin; PI3K, phosphoinositide 3-kinase; TSC, tuberous sclerosis.Adapted from: Kopelovich L, Fay JR, Sigman CC, Crowell JA |
| PMC3228878__F1 | Several types of TG2-containing adhesive / signaling complexes present on the cell surface |
| PMC3228910__F2 | Expanded representation of the KEGG pathway "colorectal cancer" |
| PMC3228973__F4 | Proposed signal transduction pathways in nodose ganglia following receptor activation with leptin and cholecystokinin-8 (CCK-8) |
| PMC3229036__F2 | Subversion of the actin cytoskeleton during viral infection |
| PMC3229221__F7 | Oncogenic EGFR signaling activates an mTORC2-NFKB pathway that promotes chemotherapy resistance |
| PMC3229968__F1 | Deciphering the role of Nuclear FactorKB in cellular senescence |
| PMC3229968__F2 | Deciphering the role of Nuclear FactorKB in cellular senescence |
| PMC3229968__F3 | Deciphering the role of Nuclear FactorKB in cellular senescence |
| PMC3229969__F2 | Roles of FGF signaling in stem cell self-renewal, senescence and aging |
| PMC3230300__F2 | Mucins in the Pathogenesis of Breast Cancer: Implications in Diagnosis, Prognosis and Therapy |
| PMC3230307__F1 | Autophagy regulation |
| PMC3230308__F1 | Autophagy pathway and relationship to mTOR signaling |
| PMC3230512__F1 | Model showing the various molecular components associated with the store-operated calcium entry pathway |
| PMC3230686__F3 | Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27 |
| PMC3230808__F7 | Regulation of CYP1A1 by capsaicin in Hepa-1c1c7 cells |
| PMC3231924__F1 | Simplified scheme for TLR signaling in enterocytes |
| PMC3231999__F1 | Immune evasion strategies of Porphyromonas gingivalis |
| PMC3232027__F2 | Identification and development of mPGES-1 inhibitors: where we are at? |
| PMC3232381__F1 | Tumour necrosis factor receptor 1 (TNFR1) and its signalling pathways |
| PMC3233056__F7 | Different expressed proteins indicated in glycolysis, TCA cycle, pentose phosphate pathway, nucleotide metabolism, amino acid metabolism, and cell wall development |
| PMC3233204__F4 | DEVELOMENT AND NEUROGENIC POTENTIAL OF MÜLLER GLIAL CELLS IN THE VERTEBRATE RETINA |
| PMC3233269__F1 | PA can be generated de novo,, by sequential enzyme-catalyzed acylations of glycerol-3-phosphate, or in response to cell signaling pathways () |
| PMC3233269__F9 | G protein-coupled receptors (GPCR) trigger dissociation of GA and GBG heterotrimeric G proteins upon agonist stimulation |
| PMC3233287__F2 | Illustration of main mechanisms of trastuzumab resistance (in red) and targeted agents to circumvent resistance (in blue) |
| PMC3233530__F2 | Insertional mutagenesis identifies multiple networks of co-operating genes driving intestinal tumorigenesis |
| PMC3233564__F3 | Mammalian MAPK signaling pathways |
| PMC3233625__F3 | Pleiotropic functions of EAPII/TTRAP/TDP2. |
| PMC3233626__F5 | NIRF interaction network |
| PMC3233666__F1 | Adaptation of endothelial cells to inflammatory stimuli and hypoxia |
| PMC3234195__F1 | Petroleum diesel, biodiesel, and ethanol |
| PMC3234240__F2 | Radiation-Induced Signaling Results in Mitochondrial Impairment in Mouse Heart at 4 Weeks after Exposure to X-Rays |
| PMC3234268__F5 | Genome Characterization of the Oleaginous Fungus Mortierella alpina |
| PMC3234318__F1 | OB inhibition by MM cells |
| PMC3234335__F1 | Hereditary Hemochromatosis and Transferrin Receptor 2 |
| PMC3234494__F3 | Cytosolic RNA sensors |
| PMC3234798__F9 | miR-26a pathway in the initiation of ASMC hypertrophy |
| PMC3234824__F9 | Diagrammatic illustration of signaling pathway involved in the regulation of miR-10b by CCN5 in breast cancer cells |
| PMC3235041__F1 | SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen |
| PMC3235480__F2 | RAF/MEK/ERK and the PI3K/AKT/mTOR signaling pathways are shown |
| PMC3235520__F1 | Proposed model of the type I interferon induction by HIV-1 and HIV-1-infected cells |
| PMC3235896__F2 | Transdifferentiation of bone-marrow-derived mesenchymal stem cells (MSCs) into the multiple skin component cells |
| PMC3235907__F1 | Clopidogrel activation and platelet aggregation pathways |
| PMC3236061__F5 | Cooperation of the genes in the DNA repair cluster |
| PMC3236209__F6 | Transcriptome Analysis of H2O2-Treated Wheat Seedlings Reveals a H2O2-Responsive Fatty Acid Desaturase Gene Participating in Powdery Mildew Resistance |
| PMC3236216__F5 | Distinct Peripheral Blood RNA Responses to Salmonella in Pigs Differing in Salmonella Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways |
| PMC3236216__F8 | Distinct Peripheral Blood RNA Responses to Salmonella in Pigs Differing in Salmonella Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways |
| PMC3236328__F1 | Main NFKB-activating pathways |
| PMC3236328__F2 | The differentiation hierarchy within the mammary epithelium and potential relationships with breast cancer subtypes |
| PMC3236456__F2 | Fungal cell wall pathogen-associated molecular patterns (PAMPs) and their host-pattern recognition receptors (PRRs) |
| PMC3236456__F3 | Hypothetical model for a molecular chitinase response to chitin-containing pathogens or particles |
| PMC3236512__F2 | Effect of FXR activation on triglyceride and cholesterol metabolism in the liver |
| PMC3236571__F7 | Resistance mechanisms in the TRAIL signaling pathway |
| PMC3236573__F3 | Ovarian cancer ascites-mediated protection from TRAIL-induced apoptosis |
| PMC3236823__F2 | Evolution of the mTOR pathway |
| PMC3237253__F3 | Adhesion of sickle red blood cells to the endothelium and cell activation |
| PMC3237753__F7 | GAq - Ca2+ signaling pathway promotes actin-mediated epidermal wound closure |
| PMC3237867__F1 | Metabolic pathways, transport, and receptors of S1P |
| PMC3237908__F4 | Schematic diagram shows the possible effect of xanthones on the apoptosis pathways |
| PMC3238080__F2 | Regulation of intracellular signaling by antiepileptics and modulators of glutamate, acetylcholine, and melatonin systems |
| PMC3238182__F1 | Involvement of miR-221/222 as downstream effectors of the EGFR-RAS-RAF-MEK pathway in progression of metastatic transformation of breast cancer tumors |
| PMC3238295__F5 | Bridged pairs and shared edges between 2ROs in the apoptosis pathway |
| PMC3238353__F1 | ER stress and activation of the UPR signalling pathways |
| PMC3238353__F2 | Crosstalk between UPR signalling pathways and lipogenesis |
| PMC3238469__F2 | Gene expression changes in cell cycle pathways |
| PMC3239234__F3 | Various signaling pathways modulated by the primary cilium |
| PMC3239343__F2 | Intracellular signalling during inflammation-induced osteoclastogenesis |
| PMC3240133__F6 | Calcium/calcineurin/NFAT signalling pathway in T cells |
| PMC3240145__F2 | Intrinsic and extrinsic pathways of apoptosis |
| PMC3240659__F3 | Repeated Small Perturbation Approach Reveals Transcriptomic Steady States |
| PMC3240668__F6 | Fibronectin - c-Myc network |
| PMC3240703__F2 | Glycosylated Synaptomatrix Regulation of Trans-Synaptic Signaling |
| PMC3240715__F3 | Molecular mechanisms of FGFR3 signaling in cartilage |
| PMC3240717__F9 | Pro-inflammatory Cytokine/Chemokine Production and Breast Tumor Invasion |
| PMC3241001__F1 | Pharmacologic Induction of CD8+ T Cell Memory: Better Living Through Chemistry |
| PMC3241422__F10 | Control of Rho1 activity through the cell cycle |
| PMC3241422__F8 | Mpk1-driven FKS2 transcription |
| PMC3241604__F7 | Proposed MAPK pathways and their inhibitors involved in EVT dysfunction during an inflammatory state |
| PMC3241690__F7 | Crosstalk between Nuclear Factor I-C and Transforming Growth FactorB1 Signaling Regulates Odontoblast Differentiation and Homeostasis |
| PMC3241725__F2 | Bacterial manipulation of mitochondrial cell death pathways |
| PMC3241725__F3 | Bacterial manipulation of host pro-survival pathway |
| PMC3241824__F1 | Operation of the mammalian Hippo pathway in mouse intestinal epithelium and human colon cancer |
| PMC3241928__F8 | Beta-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas |
| PMC3241960__F5 | Sarcolemmal actin assembly and nuclear signaling |
| PMC3241972__F1 | TOR in the immune system |
| PMC3242363__F5 | The mechanism of late PC |
| PMC3242418__F1 | HER 2: Biology, Detection, and Clinical Implications |
| PMC3242749__F4 | Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice |
| PMC3242881__F6a | Src REGULATES SPHINGOSINE-1-PHOSPHATE MEDIATED SMOOTH MUSCLE CELL MIGRATION |
| PMC3243033__F1 | Regulation of epidermal homeostasis by PCP signaling |
| PMC3243049__F3 | The autophagy pathway is affected at different steps in the various types of dementias |
| PMC3243079__F2 | Non-genomic ERA pathway |
| PMC3243091__F2 | Molecular control of palatal shelf growth and patterning |
| PMC3243113__F10 | MULTIPLE WAYS TO DIE: DELINEATION OF THE UNFOLDED PROTEIN RESPONSE AND APOPTOSIS INDUCED BY SURFACTANT PROTEIN C BRICHOS MUTANTS |
| PMC3243339__F8 | Depiction of how D1 and c-Myc proteins regulate CDDP-induced cell death, with arrow indicating induction and hyphen (-|) indicating inhibition |
| PMC3243341__F3 | Conversion of major constituents in the stem cuticular wax biosynthetic pathway |
| PMC3243350__F1 | Biosynthetic pathway of oxylipins in Arabidopsis |
| PMC3243479__F3 | Fatty acid Beta-oxidation, TG synthesis, and phospholipid biosynthesis pathways |
| PMC3243745__F6 | Metabolic pathways illustrating TCDD-elicited changes in the mouse (A) and rat (B) |
| PMC3243790__F1 | Regulation of ABCA1 Functions by Signaling Pathways |
| PMC3243812__F8 | Beta2-adrenergic receptor engagement on a B cell that will make IgE uses a unique signaling pathway to increase the level of IgE produced |
| PMC3244200__F4 | Epithelial-mesenchymal transition (EMT)-related pathways |
| PMC3244435__F1 | Thiopurine Methyltransferase Predicts the Extent of Cytotoxicty and DNA Damage in Astroglial Cells after Thioguanine Exposure |
| PMC3244904__F4 | Eukaryotic Phospholipid Synthesis and Editing.G3P produced by GPDH is converted to PA by sequential acylation reactions regulated by GPAT and LPAAT |
| PMC3245020__F3 | Disease/drug mapping is the process to map all known disease genes (pink) and all known drug targets (light blue) against all KEGG pathway maps |
| PMC3245021__F3 | Reformatted modeling of the BioCarta 'apoptotic signaling in response to DNA damage' pathway |
| PMC3245119__F2 | Non-canonical Wnt-signaling pathway |
| PMC3245201__F1 | Topography and signaling pathways triggered by selectin ligands in neutrophils |
| PMC3245324__F2 | Ischemic preconditioning (IPC): signaling pathways and targets |
| PMC3245506__F1 | Network of differentially expressed genes in HMGA1 transgenics at 2 months (nonparametric CAM approach) |
| PMC3245506__F2 | Network of differentially expressed genes in HMGA1 transgenics at 2 months (parametric approach) |
| PMC3245506__F3 | Network of differentially expressed genes in transgenics at 2 months (parametric and nonparametric approaches) |
| PMC3245506__F4 | Network of differentially expressed genes in HMGA1 transgenics at 12 months (nonparametric approach) |
| PMC3245506__F5 | Network of differentially expressed genes in HMGA1 transgenics at 12 months (parametric approach) |
| PMC3245506__F6 | Network of differentially expressed genes in transgenics at 12 months (parametric and nonparametric approaches) |
| PMC3245550__F2 | Arf Family G Proteins and their regulators: roles in membrane transport, development and disease |
| PMC3245622__F1 | PI3K/Akt signaling pathway is involved in several human cancers |
| PMC3245719__F1 | Bioenergetic regulation of cellular physiology and gene expression |
| PMC3246074__F2 | Vitamin A and immune regulation: Role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance |
| PMC3246191__F7 | Role for mTOR Signaling and Neuronal Activity in Morphine-Induced Adaptations in Ventral Tegmental Area Dopamine Neurons |
| PMC3246295__F2 | Gab2 interactions with binding partners |
| PMC3246369__F2 | Small RNAs in transcriptional gene silencing and genome defence |
| PMC3246422__F10 | PP-associated modulation of inflammatory chemokine production and repair-related processes in keratinocytes through EGFR system |
| PMC3246665__F6 | Diagram of signalling pathways indicating the possible mechanism by which sildenafil reverses the memory deficits in aged transgenic Tg2576 mice |
| PMC3246677__F2 | Regulation of viperin expression |
| PMC3246694__F2 | Representation of the resistance mechanisms to the vemurafenib |
| PMC3246786__F2 | The role of CYLD in canonical and noncanonical NFKB pathway |
| PMC3247139__F1 | Topological scheme of modeled cyclic nucleotide signaling pathways |
| PMC3247287__F8 | Profiling Insulin Like Factor 3 (INSL3) Signaling in Human Osteoblasts |
| PMC3247643__F6 | Overlay of significant canonical pathway and the connectivity in the molecular mechanism of cancer, with the eight genes in IPA canonical pathway and with the genes in Network (I) that differentially altered in PCB exposure |
| PMC3247754__F3 | Simplified view of the glucose sensing mechanisms in S |
| PMC3247963__F7 | Model illustrating that early and late ISGs induction is regulated by multiple STAT1 posttranslational modifications |
| PMC3247990__F8 | Post-induction repression of IFNB expression by YY1 in TLR3 signaling pathway |
| PMC3248020__F9 | Schematic representation of S100A7-mediated signaling that inhibits proliferation and motility in ERA+ breast cancer |
| PMC3248125__F1 | Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs |
| PMC3248149__F1 | Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence |
| PMC3248149__F3 | Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence |
| PMC3248170__F1 | Therapeutic Strategies to Overcome Acquired Resistance to BRAF or MEK Inhibitors in BRAF Mutant Cancers |
| PMC3248179__F2 | Evi1 forms a bridge between the epigenetic machinery and signaling pathways |
| PMC3248184__F1 | YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention |
| PMC3248191__F7 | Network Modeling of MDM2 Inhibitor-Oxaliplatin Combination Reveals Biological Synergy in wt-p53 solid tumors |
| PMC3248194__F3 | RIP Kinase-Mediated Necrosis as an Alternative Mechanism of Photoreceptor Death |
| PMC3248195__F1 | Elevated PI3K signaling drives multiple Breast Cancer subtypes |
| PMC3248218__F3 | NUAK2: an emerging acral melanoma oncogene |
| PMC3248275__F7 | Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice |
| PMC3248767__F2 | Bevacizumab Treatment for Advanced Breast Cancer |
| PMC3248866__F2 | HPV 16 E5 enhances growth factor signalling pathways |
| PMC3248879__F1 | Network images of FTO and candidates genes |
| PMC3248879__F4 | In silico analysis and gene expression studies suggests functional coupling between FTO and the BDNF/NTRK2-signalling pathway |
| PMC3249073__F1 | PtdEtn synthesis pathways in Plasmodium and yeast |
| PMC3249369__F4 | Three MAPK pathways in yeast share common components and also contain pathway-specific factors |
| PMC3249400__F1 | AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism |
| PMC3249400__F2 | AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism |
| PMC3249400__F4 | AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism |
| PMC3249418__F3 | Migration of marginal zone precursor B cells regulated by type I interferon (IFN) and IL-17 |
| PMC3249608__F2 | RA-dependent non-transcriptional involvement in neurite outgrowth |
| PMC3249681__F8 | Simplified diagram depicting the proposed signaling pathway of the CB1 activation that inhibits the activity of small GTPase RhoA to inhibit motility of PC-3 cells |
| PMC3250080__F1 | CR-associated signaling and some of its key players |
| PMC3250173__F7 | TLR3/TLR4-mediated signaling pathways |
| PMC3250228__F3 | FOLATE-ALCOHOL AND CANCER PATHWAY HYPOTHESES |
| PMC3250521__F4 | Inhibition of isoprenoid biosynthetic pathway by ATST [modified from Holstein et al |
| PMC3250525__F3 | Visualization of the quantity of genes differentially regulated by Gamma-tocotrienol (GT3) and Alpha-tocopherol (aTOC) using the KEGG cell cycle pathway |
| PMC3250614__F2 | TGFB signal transduction pathway and targets for therapeutic intervention |
| PMC3251006__F5 | ECM-receptor interaction and focal adhesion pathway |
| PMC3251532__F5 | The lymphocte-specific gene (A) or urine peptide (B) markers |
| PMC3251560__F7 | Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes |
| PMC3251560__F8 | Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes |
| PMC3251560__F9 | Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes |
| PMC3251651__F4 | Novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy |
| PMC3251736__F2 | Ingenuity pathway analysis (IPA) of the EGFR ablation signature with oncogenic (A) and wildtype Ras (B) |
| PMC3251842__F2 | TGFB response pathway |
| PMC3251883__F4 | Proposed mechanism for VEGFA165 induced tumour growth |
| PMC3252343__F4 | Expression Signature of IFN/STAT1 Signaling Genes Predicts Poor Survival Outcome in Glioblastoma Multiforme in a Subtype-Specific Manner |
| PMC3252370__F10 | Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability |
| PMC3252731__F1 | TLR4 signaling pathway is highly regulated |
| PMC3252742__F4 | Apoptotic pathway in cardiac myocytes |
| PMC3252833__F1 | Fas-induced apoptotic signalling pathway |
| PMC3252833__F3 | Sensitisation of type 2 cancer cells towards DR-induced killing by synthetic IAP antagonists |
| PMC3252978__F7 | Summary of the results presented in this study |
| PMC3253010__F3 | A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. |
| PMC3253327__F1 | Acute and Chronic Regulation of Aldosterone Production |
| PMC3253327__F2 | Acute and Chronic Regulation of Aldosterone Production |
| PMC3253558__F1 | Conserved Herpesvirus Kinases Target the DNA Damage Response Pathway and TIP60 Histone Acetyltransferase to Promote Virus Replication |
| PMC3253704__F1 | Prominent signaling pathways involved with PDAC tumoral compartment and stromal compartment crosstalk |
| PMC3253886__F4 | IRF signaling pathway that was generated from pathway analysis of proteins with significant fold changes across both studies |
| PMC3253915__F2 | Innovative Therapy for Classic Galactosemia - Tale of Two HTS |
| PMC3254042__F7 | Signaling pathways involved in synaptic plasticity and neuroglia functions with associated molecules and cellular tasks (analysis based on Ingenuity IPA software) |
| PMC3254618__F3 | Identification of Gene Networks and Pathways Associated with Guillain-Barré Syndrome |
| PMC3254631__F5 | MiRNA Expression by Dietary Polyphenols in apoE Deficient Mice: A New Mechanism of the Action of Polyphenols |
| PMC3254670__F1 | Metabolic connections during apoptotic cell engulfment |
| PMC3255271__F1 | Study schema |
| PMC3255316__F1 | Factors affecting the viability of dopamine neurons |
| PMC3255319__F1 | Oncogenic and tumor suppressor control of metabolism |
| PMC3255710__F2 | Fine adjustment of autophagy by the AMPK-mTORC1-Ulk1/2 kinase network |
| PMC3255783__F7 | Model depicting the potential roles of Hrq1 in NER-based lesion processing |
| PMC3255869__F1 | TLR4 signaling pathway |
| PMC3255978__F7 | Proposed mechanisms underlying the regulatory control of fibrosis development by the PAI-1/uPA balance in aged-associated muscle dystrophy progression |
| PMC3256209__F5 | Molecular Mechanisms of Fiber Differential Development between G. barbadense and G. hirsutum Revealed by Genetical Genomics |
| PMC3256223__F1 | Modeling of miRNA and Drug Action in the EGFR Signaling Pathway |
| PMC3256462__F1 | Basic signaling pathways and relevant targets together with their inhibitors associated with endocrine resistance Estrogen receptor alpha (ER) and the growth factors (esp |
| PMC3256499__F2 | VEGF pathway and site of action of the inhibitors |
| PMC3256849__F6 | A model for Kv1.3-mediated signaling pathway in human T effector memory cell differentiation |
| PMC3256879__F8 | A hypothetical diagram of the involvement of ATF6 in BMP2-induced osteoblast differentiation |
| PMC3256998__F5 | Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNFA) Induced Inflammatory Response in Bovine Cells |
| PMC3256998__F6 | Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells. |
| PMC3257109__F3 | BMP signaling in motor neurons |
| PMC3257556__F2 | Known components of the PCP signalling pathway and related cellular functions |
| PMC3257565__F2 | HSC cell cycle entry is regulated by a complex network of cell-intrinsic and cell-extrinsic factors |
| PMC3257580__F1 | Kruppel-like factors in lymphocyte biology |
| PMC3257753__F1 | TWEAK-Fn14 signaling system |
| PMC3258214__F1 | Bcl-3 signaling cascade |
| PMC3258305__F2 | The Long History of Iron in the Universe and in Health and Disease |
| PMC3258432__F6 | Factors shown to promote or inhibit the vascular normalization phenotype in tumors |
| PMC3258560__F1 | Signal transduction by TGFB family members |
| PMC3258586__F1 | PI3K pathway activated by EGF-stimulated EGFR or by the constitutively activated EGFRvIII |
| PMC3259192__F2 | Sphingolipid Signaling and Hematopoietic Malignancies: To the Rheostat and Beyond |
| PMC3259218__F1 | Gemcitabine metabolic pathway genetic polymorphisms and response in non-small cell lung cancer patients |
| PMC3259275__F2 | ATM interaction with metabolic signaling pathways |
| PMC3259514__F1 | Different signaling pathways leading to the induction of virus stress-inducible genes (VSIGs) and interferon-stimulated genes (ISGs) |
| PMC3259815__F8 | Signaling through PAK in the hyperosmotic response pathway |
| PMC3260001__F1 | Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells |
| PMC3260150__F2 | Identification of a Potential Ovarian Cancer Stem Cell Gene Expression Profile from Advanced Stage Papillary Serous Ovarian Cancer |
| PMC3260274__F5 | Tumour Suppressive Function and Modulation of Programmed Cell Death 4 (PDCD4) in Ovarian Cancer |
| PMC3260452__F2 | Simplified model of the leptin signaling pathway |
| PMC3260518__F1 | Invisible hand: regulation of RHO GTPases by RHOGDIs |
| PMC3260548__F1 | The signaling cascade in response to the release of dsRNA from LRV particles, production of IFNB and secretion of proinflammatory cytokines and chemokines |
| PMC3260552__F4 | Melanoma signaling networks, progression, and influences by the BCL-2 family |
| PMC3260807__F1 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health |
| PMC3260807__F2 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health |
| PMC3260807__F4 | Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health |
| PMC3260814__F1 | Personalizing Therapy with Targeted Agents in Non-Small Cell Lung Cancer |
| PMC3260854__F6 | FosB-mediated regulation of ECM genes by mechanical signaling in bladder smooth muscle |
| PMC3260860__F6 | Scheme of the EGR-1/GGPPS/ERK 1/2 pathway |
| PMC3260921__F2 | Integrin signalling pathway |
| PMC3261278__F1 | Synaptic translation and signaling pathways modulated by FMRP (a) and dysregulation of these pathways in the absence or significant reduction of FMRP (b) |
| PMC3261278__F2 | Targeted treatments for fragile X syndrome. |
| PMC3261582__F1 | JNK signaling enhances the compensatory proliferation of the neighboring cells, stem cells or cancer stem cells (CSCs) |
| PMC3261702__F4 | Structural coverage of the core vision pathway and its links to other functional modules |
| PMC3261822__F3 | IPA-based pathway analysis of differential expressed genes |
| PMC3262099__F8 | The host cell EGF signaling pathway and proteins downstream of the EGF receptor that are activated in response to C |
| PMC3262193__F3 | Signaling pathways and proteins that increase or decrease STAT5 signaling in normal mammary epithelial cells |
| PMC3262331__F2 | Schematic signaling pathway mediated by the L-CBM complex in T and B lymphocytes.Notes: The L-CBM complex acts in the canonical NFKB (p65/p50, cRel/p50) activation pathway mediated by IKKB downstream of TCRs and BCRs |
| PMC3262331__F3 | Schematic signaling pathway mediated by the L-CBM complex in NK cells.Notes: The L-CBM complex acts in the canonical NFKB activation pathway through activating NK cell receptors (NKR) such as Ly49H, Ly49D, NK1.1, NKG2D, FcGRIII, etc |
| PMC3262546__F1 | The p14-p53-p21 and p16-Rb signaling pathways involved in fibroblast senescence |
| PMC3262611__F1 | Folic acid metabolism |
| PMC3262916__F2 | Mechanism of action of vitamin D and the vitamin D receptor in colorectal cancer prevention and treatment |
| PMC3262938__F2 | N-glycan biosynthetic pathways in eukaryotes and glycoengineering |
| PMC3262999__F1 | Interaction between Jak2/Stat5 signaling and the PI3K/Akt1 pathway in mammary epithelial cells |
| PMC3263309__F1 | Notch, Wnt, and Hedgehog signaling pathways regulate normal and stem cell fate |
| PMC3263503__F8 | Schematic depiction of crosstalk between Notch and HIF-1A |
| PMC3263550__F2 | Parkinson's disease pathway from the KEGG disease database |
| PMC3263561__F2 | Interaction between glia and neurons may lead to neuron damage and death |
| PMC3263596__F3 | TGFB pathway in NetSlim |
| PMC3263689__F2 | VHL complex targets HIF-1A and HIF-2A for ubiquitin-mediated degradation |
| PMC3263689__F5 | FLCN pathway |
| PMC3264131__F1 | Metabolic pathway of C |
| PMC3264379__F9 | Proposed model for regulation of HCV replication mediated by the Ras/Raf/MEK pathway |
| PMC3264680__F3 | Diagram of IGF/INSR/IGF1R signaling pathway |
| PMC3265021__F2 | Signal transduction events that link ER stress to inflammation |
| PMC3265067__F7 | Phospholipid biosynthetic pathways |
| PMC3265661__F1 | Putative role of the mTOR pathway in pathogenesis and epileptogenesis of focal cortical malformations |
| PMC3265777__F2 | Context-dependent regulation of Rho GTPase signaling |
| PMC3265821__F1 | Change in RAF isoform usage in response to a RAS mutation |
| PMC3265866__F7 | PGC-1Alpha- and AMPK-mediated regulation of IL1Rn expression in hepatocytes |
| PMC3266027__F1 | Activation of EGFR signaling in non-small-cell lung cancer (NSCLC) can occur via disruption of several different components at multiple levels of the pathway |
| PMC3266662__F3 | Correlations of genes in central carbon metabolism with SPPR |
| PMC3266773__F10 | CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression |
| PMC3266776__F2 | Understanding pRb: toward the necessary development of targeted treatments for retinoblastoma |
| PMC3266783__F2 | Basal cell carcinoma – molecular biology and potential new therapies |
| PMC3267157__F2 | P73 pathway and its regulators.A simplified view of the p73 pathway, of its regulators, and of the molecules that directly or indirectly can modulate its function |
| PMC3267662__F2 | IGF1R-IR/PI3K/Akt/mTOR pathway and its manipulation through diet |
| PMC3267701__F1 | Amyloid precursor protein (APP) processing pathway [-] |
| PMC3267732__F4 | Deeply Branching Thermophilic Bacterium with an Ancient Acetyl-CoA Pathway Dominates a Subsurface Ecosystem |
| PMC3267756__F9 | Coxiella burnetii Induces Apoptosis during Early Stage Infection via a Caspase-Independent Pathway in Human Monocytic THP-1 Cells |
| PMC3268129__F1 | Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins |
| PMC3268187__F3 | Representation of signalling transduction via adiponectin receptor activation |
| PMC3268188__F2 | Tumour suppressor p53 regulation and signalling |
| PMC3268389__F1 | Pathways and compartmentation of FA supply for TAG synthesis in plants |
| PMC3268503__F6 | The Chl branch.The first step of the Chl branch is the insertion of Mg2+ into Proto IX |
| PMC3268617__F2 | Dys-Syn-nNOS pathway and miRNAs coordinate the muscle differentiation program |
| PMC3268901__F1 | The PTEN/mTOR signaling pathway |
| PMC3268941__F1 | Canonical Wnt/Beta-catenin and non-canonical Wnt signaling pathways |
| PMC3269020__F1 | Pathways involved in aging |
| PMC3269020__F3 | Role of miRNAs in aging of mice |
| PMC3269021__F8 | Interaction of TOR pathway members for the regulation of phagocytosis |
| PMC3269300__F1 | DN Tregs employ multiple mechanisms to exert antigen-specific control over immune responses |
| PMC3269610__F1 | TGFB signaling and negative regulation in bone formation |
| PMC3269610__F2 | BMP signaling and negative regulation in bone formation |
| PMC3269658__F5 | Differentiation pathways of CSCs |
| PMC3269678__F2 | Signaling pathways leading to transcription factors activation in response to UV-radiation |
| PMC3269833__F6 | Potential regulatory mechanism of the identified gene switches for breast cancer |
| PMC3270028__F6 | Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling |
| PMC3270058__F9 | Endothelial adaptive response to moderate hypothermia (25°C/72 h) |
| PMC3270095__F4 | Regulatory network for PACAP-responsive genes |
| PMC3270101__F6 | Pathway map related to cisplatin-induced hepatotoxicity based on proteomic and genomic analysis |
| PMC3270265__F3 | Glucose metabolism in cancer cells |
| PMC3270265__F5 | Regulation of cell death by glucose metabolism |
| PMC3270444__F5 | Putative inhibitory pathway of LPS-activated inflammatory signaling responses by peptide K5 |
| PMC3270467__F1 | Putative galanin-mediated neuronal pro- and antinociceptive mechanisms in the dorsal horn of the spinal cord |
| PMC3270883__F1 | Exiting from uncharted territory: hepatitis C virus assembles in mouse cell lines |
| PMC3271045__F4 | Schematic summary of striatal gene expression changes in response to SNCA overexpression |
| PMC3271076__F8 | Novel YY1-miR-1 Regulatory Circuit in Skeletal Myogenesis Revealed by Genome-Wide Prediction of YY1-miRNA Network |
| PMC3271643__F3 | Putative mechanism of estrogen action in rat Sertoli cells |
| PMC3271653__F1 | Testosterone signaling pathways |
| PMC3271661__F3 | Summary of Kit/Kitl signaling during spermatogenesis |
| PMC3271860__F3 | IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS |
| PMC3271860__F7 | THE ROLE OF IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS |
| PMC3272142__F4 | Signaling pathways promoting trophoblast invasion and migration |
| PMC3272176__F1 | Signal Transduction pathways downstream of activated HER family of receptors |
| PMC3272624__F1 | Schematic depicting mTORC1 signaling in a NAC a medium spiny neuron with anterogradely transported BDNF being released from a VTA dopamine neuron terminal and glutamate released from a prefrontal cortex projection neuron |
| PMC3272682__F1 | Recognition of Pathogenic Nucleic Acids by Patterns Recognition Receptors and Signaling |
| PMC3272705__F1 | Subcellular itineraries of paradigmatic substrates of ubiquitin-dependent sorting pathways |
| PMC3272823__F3 | Involvement of the ERK pathway in the TGF-Beta-induced epithelial-mesenchymal transition |
| PMC3272847__F2 | E6-mediated survival signaling |
| PMC3272851__F3 | Extrinsic pathway of apoptosis |
| PMC3272882__F3 | DRD2/GSK3B/DISC1 pathway modified from Beaulieu et al |
| PMC3273421__F2 | Myostatin and activin signaling in muscle |
| PMC3273665__F2 | SREBPs in the innate immune response |
| PMC3273847__F1 | Innate Immunity in the Host Defense Against intestinal Bacterial Pathogens |
| PMC3274456__F3 | Lipopolysaccharide (LPS)-dependent and nuclear factor (NF)KB-mediated activation of proinflammatory cytokines |
| PMC3274489__F1 | Overview of the mevalonate pathway |
| PMC3274818__F1 | Activation of an RTK induces dimerization and downstream phosphorylation of non-receptor tyrosine kinases |
| PMC3275089__F1 | Schematic overview of the ABeta-Cav1.2-ptau-autophagy pathway |
| PMC3275361__F3 | Signaling and cross talk of the PTH and Wnt signaling pathways in osteocytes |
| PMC3275500__F1 | The Ras-MAPK and TGFB pathways |
| PMC3275548__F3 | Liver from Campari tomato treatment |
| PMC3275780__F2 | T cell activation |
| PMC3275810__F2 | Schematic display of the molecular interactions of apoptosis related molecules in dental apoptosis indicating the central position of the mitochondria pathway, which has been shown to be essential |
| PMC3276354__F1 | Canonical Wnt (Wnt/Beta-catenin) signaling pathway (adapted from Ref |
| PMC3276397__F1 | Effects of VitA in gut-associated lymphoid tissue |
| PMC3276472__F1 | Schematic in vivo biosynthetic pathway from 18:3n3 and 18:2n6 mediated by ELOVL4 and other ELOVL family proteins |
| PMC3276511__F2 | Mass Homozygotes Accumulation in the NCI-60 Cancer Cell Lines As Compared to HapMap Trios, and Relation to Fragile Site Location |
| PMC3276621__F2 | Pathways for the synthesis of glycerolipids and their subcellular localization |
| PMC3276974__F2 | Hypothetical model of LRRK2-mediated regulation of the miRNA pathway |
| PMC3277127__F5 | Curation of phosphoproteomic profiling and bioinformatics delineates distinct tyrosine kinase signaling pathways in an oncogene-specific manner |
| PMC3277529__F1 | Proposed model for TIMP-1-mediated suppression of the Wnt/Beta-catenin pathway via let-7f in human mesenchymal stem cells (hMSCs) |
| PMC3277712__F1 | Importance of cytokine signalling for CD4+ T-cell differentiation |
| PMC3277713__F1 | A schematic diagram of different components making up the interleukin-23 (IL-23) and IL-12 receptors and the common signal transduction and activator of transcription 4 (STAT4) activation pathway |
| PMC3277752__F2 | Browsing the ApoptoProteomics database |
| PMC3278439__F4 | Analysis of the Fibroblast Growth Factor System Reveals Alterations in a Mouse Model of Spinal Muscular Atrophy |
| PMC3278537__F2 | Signaling Pathways Underlying the Pathophysiology and Treatment of Depression: Novel Mechanisms for Rapid-Acting Agents |
| PMC3278592__F3 | The pleiotropic effects of erythropoietin in infection and inflammation. |
| PMC3278830__F3 | Functions related to hepatic cultures.Subgraphs of a hepatocyte response network induced by genes annotated with MSigDB gene sets |
| PMC3278831__F4 | Sample subnetwork formation |
| PMC3278889__F4 | TLR4 signaling to NFKB |
| PMC3278889__F5 | T-cell receptor (TCR) signaling to NFKB |
| PMC3278889__F6 | CD40 signaling to the alternative NFKB pathway |
| PMC3279601__F1 | The Immunologic Revolution: Photoimmunology |
| PMC3279615__F3 | Nucleotide excision repair (NER) pathway |
| PMC3279640__F1 | Bi-potential gonad development to either testis or ovary |
| PMC3279640__F2 | Known genes and pathways of the different cell types of the developing testis in mouse (modified from Wainwright and Wilhelm ) |
| PMC3279748__F2 | GSK-3 in NMDAR-LTD |
| PMC3279755__F1 | Signaling pathways of the fibroblast growth factor receptor in neural stem cells |
| PMC3279943__F1 | PI3K and STAT3: a New Alliance |
| PMC3280275__F6 | Kinome-Wide Functional Genomics Screen Reveals a Novel Mechanism of TNFAlpha-Induced Nuclear Accumulation of the HIF-1A Transcription Factor in Cancer Cells |
| PMC3280674__F1 | Fatty Heart, Cardiac Damage, and Inflammation |
| PMC3280691__F1 | Beta-catenin signaling: a novel mediator of fibrosis and potential therapeutic target |
| PMC3280986__F7 | Behavioral and Immune Responses to Infection Require GAq- RhoA Signaling |
| PMC3281071__F4 | RNA-seq Reveals Novel Transcriptome of Genes and Their Isoforms in Human Pulmonary Microvascular Endothelial Cells Treated with Thrombin |
| PMC3281082__F7 | ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer |
| PMC3281277__F1 | Proteolytic processing of the BACE1 substrates APP and NRG1 |
| PMC3281420__F1 | Schematic overview of the multifunctional roles of c-FLIP in the TRAIL-triggered apoptosis pathway as well as activating various anti-apoptotic and cell survival signaling pathways |
| PMC3281554__F2 | Possible mechanisms of regulation of DP thymocytes by multiple factors |
| PMC3281571__F1 | Simplified view of the mTOR pathway |
| PMC3281571__F2 | MTOR pathway |
| PMC3281591__F4 | Mitochondrial-dependent apoptosis |
| PMC3281607__F2 | Antioxidant roles of Prx I, Prx III, and Srx in ethanol-fed mouse liver |
| PMC3281623__F9 | Toxoplasma acquires fatty acids through a complex network of synthesis and uptake |
| PMC3281634__F1 | Simplified diagram of the unfolded protein response |
| PMC3281649__F9 | Proposed model for the inhibition of Notch1 signaling pathway by Fe65 |
| PMC3281723__F2 | Role of PHLPP in terminating oncogenic signaling pathways |
| PMC3282414__F2 | Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities. |
| PMC3282946__F4 | miR-23b and tretinoin, which was associated with this miRNA in thyroid cancer, shared the common target genes, ALDH1A1 and ALDH1A2 |
| PMC3282989__F2 | Recapitulation of heart development can provide useful insight for optimizing differentiation protocols |
| PMC3283059__F2 | Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway displaying transcripts in mitogen-activated protein kinase (MAPK) signaling pathway |
| PMC3283059__F4 | Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway display transcripts in cell cycle pathway |
| PMC3283604__F6 | TSC1/2 Signaling Complex Is Essential for Peripheral Naïve CD8+ T Cell Survival and Homeostasis in Mice |
| PMC3283669__F1 | Gis1 and Rph1 Regulate Glycerol and Acetate Metabolism in Glucose Depleted Yeast Cells |
| PMC3283716__F1 | Novel Classification of Lung Cancer into Molecular Subtypes |
| PMC3283740__F4 | Matrix-Bound PAI-1 Supports Cell Blebbing via RhoA/ROCK1 Signaling |
| PMC3283951__F5 | The acetate/mevalonate pathway for the formation of IPP, the basic five-carbon unit of terpenoid biosynthesis |
| PMC3284544__F4 | Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis |
| PMC3284544__F5 | Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis |
| PMC3284544__F6 | Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis |
| PMC3285038__F1 | Schematic of Smads mediated TGFB signaling pathway |
| PMC3285038__F2 | Schematic summarizing the role of signaling Smads in epithelial carcinogenesis |
| PMC3285217__F1 | Drosophila signaling pathways that regulate humoral responses |
| PMC3285254__F4 | Copper in microbial pathogenesis: meddling with the metal |
| PMC3285356__F6 | Schematic presentation of the ROS-DAPK-PKD1-GLUT4 axis as a novel pathway involved in contraction-induced glucose but not LCFA uptake |
| PMC3285363__F7 | Hypothetical scheme illustrating a possible mechanism of mLDL-mediated regulation of C3 expression and secretion by human macrophages |
| PMC3285398__F1 | Toll-like Receptors (TLRs) recognize specialized structural motifs on the microbes known as pathogen-associated molecular patterns (PAMPs) |
| PMC3285398__F2 | Proposed mechanisms of interaction between TLRs and MUCs: I |
| PMC3285438__F5 | Simplified signaling pathway of the effects of resveratrol involved in metabolic control in the skeletal muscle |
| PMC3285457__F6 | Smad7 is Inactivated through a Direct Physical Interaction with the LIM Protein Hic-5/ARA55 |
| PMC3285553__F3 | Additional mechanisms by which Wnt/Beta-catenin signaling can be modulated in cancer |
| PMC3285553__F4 | Schematic illustrating numerous small molecules and biological compounds identified in the literature that inhibit Wnt/Beta-catenin signaling at various points in the pathway |
| PMC3285581__F7 | Msx Homeobox Genes Critically Regulate Embryo Implantation by Controlling Paracrine Signaling between Uterine Stroma and Epithelium |
| PMC3285584__F9 | Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway |
| PMC3286397__F11 | Campylobacter jejuni-induced Cdc42 activation |
| PMC3286676__F1 | Thyroid iodide efflux: a team effort? |
| PMC3286890__F1 | Wnt/Beta-catenin signalling and Beta-catenin role in adhesion in glioma cells |
| PMC3286973__F2 | Cell-line subtypes have unique SuperPathway network features |
| PMC3286973__F3 | Pathway diagrams can be used to predict response to therapies |
| PMC3287012__F1 | Signaling through CD44: hyaluronan binding to a receptor such as CD44 or RHAMM will cause a conformational change in the receptor |
| PMC3287202__F6 | Overview of pre-miRNA processing |
| PMC3287362__F1 | The anatomic and molecular mechanisms of sepsis-mediated sympathoexcitation and ghrelin's anti-inflammatory effect via sympathoinhibition |
| PMC3287363__F7 | Working model of ID/anemia-suppressed hippocampal IGF signaling |
| PMC3287489__F2 | Cell cycle pathway and the significant genes on cell cycle-related miRNAs |
| PMC3287579__F1 | Adapted from |
| PMC3287586__F2 | Preimplantation development pathway |
| PMC3288148__F1 | Three pathways contribute to cellular BH4 levels, the synthesis pathway, the salvage pathway and the recycling pathway |
| PMC3288293__F1 | Molecular mechanism of senescence |
| PMC3288319__F4 | Phytoestrogens on ECs and VSMCs |
| PMC3288605__F2 | Pathway of formation and catabolism of HDL particles |
| PMC3288643__F1 | Ephs and Ephrins in Cancer: Ephrin-A1 Signaling |
| PMC3288889__F5 | Ephrin-B cleavage and signaling |
| PMC3289121__F5 | IPA illustrating the predicted effect of milk removal on PI3K signaling in T lymphocytes |
| PMC3289531__F2 | A, Hepatic BCAA metabolism |
| PMC3289598__F1 | Molecular Mechanisms of Drug Resistance in Natural Leishmania Populations Vary with Genetic Background |
| PMC3289952__F1 | Selected essential fatty acids molecular mechanisms |
| PMC3289952__F2 | Proposed role of essential fatty acids in "micromanaging" molecular actions |
| PMC3290617__F1 | Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin |
| PMC3290818__F1 | TLR signalling pathway |
| PMC3291304__F1 | Protein quality control systems are potential targets for mechanism-based treatments of demyelinating Charcot-Marie-Tooth disease (CMT) |
| PMC3291562__F4 | Function-Based Discovery of Significant Transcriptional Temporal Patterns in Insulin Stimulated Muscle Cells |
| PMC3291637__F1 | General scheme for biogenesis of Fe-S clusters in mammalian cells |
| PMC3291637__F2 | Proposed differences in the localization of Fe-S cluster biogenesis proteins in S |
| PMC3291787__F1b | Targeting the EGFR signaling pathway in cancer therapy |
| PMC3291787__F2 | Targeting the EGFR signaling pathway in cancer therapy |
| PMC3291787__F3 | Targeting the EGFR signaling pathway in cancer therapy |
| PMC3291789__F1 | Targeting the p53 signaling pathway in cancer therapy - The promises, challenges, and perils |
| PMC3291810__F8 | PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling |
| PMC3291999__F3 | MTOR signalling pathway (see text for details) |
| PMC3292304__F4 | Gene functional association networks for selected pathways in p53 dataset |
| PMC3292309__F3 | Activation of inflammatory mediators in pancreatic Beta-cells in type 1 diabetes |
| PMC3292500__F3 | Top scored pathway map affected by BaP "Apoptosis and survival_Endoplasmic reticulum stress response" |
| PMC3292584__F4 | Differential gene expression in the TLR signalling pathway |
| PMC3292751__F3 | Regulation of mammalian mitophagy |
| PMC3292895__F1 | Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics |
| PMC3292920__F1 | Diagram shows the enzyme points (in cycle) on which the effects of n-3 PUFA might operate in the homocysteine metabolic pathway of relevance |
| PMC3293036__F1 | The Wnt signaling pathway in cancer cells |
| PMC3293571__F7 | EMT downstream of TGFB and HMGA2 |
| PMC3293584__F1 | Schematic of folate-mediated one-carbon metabolism in the cytoplasm and nucleus |
| PMC3293632__F1 | Control of the EGFR pathway and cell cycle entry by miRNAs |
| PMC3293935__F4 | Known apoptotic targets of P53 |
| PMC3293992__F11 | Suppression of the NFKB Pathway by Diesel Exhaust Particles Impairs Human Antimycobacterial Immunity |
| PMC3294063__F1a | Molecular Pathways: Beta-adrenergic signaling in cancer |
| PMC3294166__F8 | KEGG pathway mapping overlay for acidic pHe upregulated genes pertinent to OXPHOS |
| PMC3294197__F3 | Ingenuity Pathway Analysis of genes that are differentially methylated (P<1.8 × 10-6) between normal mucosa of cancer patients and controls |
| PMC3294214__F2 | Signaling pathways regulating epithelial immune response in nematode epidermal (a) and intestinal (b) cells, adapted from Tan and Shapira |
| PMC3294376__F4 | O-linked N-acetylglucosamine (O-GlcNAc) is a nutrient sensor and underlies glucose toxicity |
| PMC3294420__F2 | Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links |
| PMC3294420__F3 | Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links |
| PMC3294426__F3a | Into the Eye of the Cytokine Storm |
| PMC3294429__F4 | The NDT80 transcriptional induction pathway |
| PMC3294670__F7 | Mechanisms of control of Listeria entry by the type IA PI 3-kinase signaling pathway |
| PMC3294814__F1 | Proposed biosynthetic pathway of RQ (compound 1) |
| PMC3295030__F1 | Simplified description of the insulin/IGF-1 signal transduction (IIS) pathway in invertebrates and mammals |
| PMC329503__F9 | The roles of Ras and Mob2 in S |
| PMC3295063__F2 | NFKB in Aging and Disease |
| PMC3295081__F1 | Age-related Dysregulation of Inflammation and Innate Immunity: Lessons Learned from Rodent Models |
| PMC3295195__F10 | A novel mechanism linking ROS/Src/caveolin-mediated activation of the EGFR-ERK signaling pathway to chronic Ang II exposure-induced EMT in cultured renal tubular epithelial cells |
| PMC3295626__F1 | JAK-STAT intracellular signaling pathway in myelofibrosis |
| PMC3295657__F6 | Pathway model for interleukin (IL)-1A and tumor necrosis factor (TNF)-Alpha-induced inhibition of human skeletal muscle cell (HuSKMC) differentiation |
| PMC3295664__F1 | Methanol utilization (MUT) pathway in P |
| PMC3295899__F2 | Matricellular Protein Thrombospondin-1 Globally Regulates Cardiovascular Function and Responses to Stress via CD47 |
| PMC3296020__F2 | Possible metabolic pathways modulated by a CO-sensitive CBS inhibition |
| PMC3296080__F1 | Interactions between insulin-like growth factor-1 receptor (IGF-1R), insulin receptor (IR), and epidermal growth factor receptor (EGFR) signaling pathways |
| PMC3296187__F1 | Schematic representation of the RKIP signaling pathway and its effects on metastatic progression to the bone |
| PMC3296202__F1 | Pathways involved in diabetes-induced EPCs toxicity and possible strategies to reverse EPCs damage during bone marrow mobilization |
| PMC3296207__F1 | Intrinsic and exrtinsic pathways of anoikis |
| PMC3296242__F8 | Models of interactions within the destruction complex (A) and the catalytic cycle of the destruction complex (B) |
| PMC3296254__F5 | Arginine metabolic network |
| PMC3296254__F7 | Lysine biosynthetic pathway |
| PMC3296744__F11 | Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development |
| PMC3296768__F5 | Targeting Bone Remodeling by Isoflavone and 3,3'-Diindolylmethane in the Context of Prostate Cancer Bone Metastasis |
| PMC3296807__F1 | Oncogenes and tumor suppressors associated with the regulation of autophagy |
| PMC3296959__F2 | Innate immunity and the ubiquitin-proteasome system in PD |
| PMC3297025__F1 | IL-1 signaling leads to actin stress fiber formation |
| PMC3297025__F2 | BTB restructuring and spermiation are coordinated by IL-1A during spermatogenesis |
| PMC3297581__F6 | Tcf7 Is an Important Regulator of the Switch of Self-Renewal and Differentiation in a Multipotential Hematopoietic Cell Line |
| PMC3298518__F2 | Pathogenesis of neurodegenerative diseases is significantly associated with oxidative stress |
| PMC3298530__F7 | Tentative scheme for luteolin regulation of the IGF-IR signaling pathway in HT-29 human colon cancer cells |
| PMC3298572__F7 | Model for HuR NEDDylation |
| PMC3298638__F2 | Screening for small molecule inhibitors of embryonic pathways: Sometimes you gotta crack a few eggs |
| PMC3298733__F1 | New therapies targeting the deregulated pathways to treat TICs in pancreatic cancer |
| PMC3298845__F1 | Wnt/Beta-catenin signaling pathway in liver biology and disease |
| PMC3299304__F3 | Molecular mechanisms of HGF-c-Met-mediated signaling for inhibiting TLR4-mediated NFKB activation in macrophages |
| PMC3299342__F3 | Signaling by PERK, IRE1, and ATF6 |
| PMC3299554__F1 | Diagrammatic representation of the Akt signaling pathway.Notes: Activation of receptor tyrosine kinase (RTK) by growth factor binding activates PIK3 |
| PMC3302314__F1 | Signaling cascade following TLR2/TLR4, TLR7/TLR8, and TLR3 activation with envelope glycoprotein, ssRNA, and dsRNA, respectively |
| PMC3302314__F2 | Left half, signaling via IPS-1 following dsRNA/ssRNA recognition by RIG-I and MDA5 |
| PMC3302445__F7 | How BRG1 and CHD4 antagonistically influence Wnt signaling during yolk sac vascular development |
| PMC3302843__F10 | Hypoxia Reduces Arylsulfatase B Activity and Silencing Arylsulfatase B Replicates and Mediates the Effects of Hypoxia. |
| PMC3303469__F1 | Hypoxia inducible factor (HIF) pathway |
| PMC3303474__F3 | Bibliosphere network of ubiquinol-sensitive genes regulated in liver tissues of C57BL6J mice |
| PMC3303581__F1 | Myostatin signals through the ActRIIB-ALK4/5 heterodimer activate Smad2/3 with blocking of MyoD transactivation in an autoregulatory feedback loop |
| PMC3303591__F1 | Stimulation of PI-3K/Akt signaling pathway after activation of IR/IGF-1R mediates insulin neuroprotection against damaging conditions |
| PMC3303610__F3 | Ang-(1-7) signaling in cardiomyocytes |
| PMC3303613__F1 | Signaling pathways in the pathogenesis of nasopharyngeal carcinoma (NPC) |
| PMC3303816__F3 | Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis |
| PMC3303893__F1 | The schematic diagram of base excision repair (BER) pathway for DNA repair throughout the cell cycle |
| PMC3303935__F1 | Toll-Like Receptors in Chronic Pain |
| PMC3304012__F3 | Landscape of EGFR Signaling Network in Human Cancers: Biology and Therapeutic Response in Relation to Receptor Subcellular Locations |
| PMC3304298__F1 | AKT signaling pathway |
| PMC3304564__F1 | PI3K/AKT signaling module and cross-talk with other pathway |
| PMC3304673__F1 | Association of the canonical interferon pathway with the IRF5 haplotype |
| PMC3305403__F4 | The Nucleoside Diphosphate Kinase Gene Nme3 Acts as Quantitative Trait Locus Promoting Non-Mendelian Inheritance |
| PMC3305973__F2 | Sixteen genes associated with enzastaurin response were established by pathway analyses and prediction of drug response using an eight-gene signature |
| PMC3306173__F6 | Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis |
| PMC3306451__F2 | Integration of mitochondrial oxidative and antioxidant pathways by PGC-1A |
| PMC3306451__F3 | Potential role for PRC in orchestrating a balance between cell cycle entry and the inflammatory response to metabolic stress |
| PMC3306972__F1 | ABPP processing, the adaptor proteins interacting with its intracellular domain and the pathway leading to ERK1/2 activation |
| PMC3306972__F2 | The intracellular pathway by which ABPP and PS1 control the activation of the MAPK/ERK1/2 cascade and their final biological effects |
| PMC3306981__F1 | Summarized the signaling mechanisms of various matricellular proteins contributing to cancer progression |
| PMC3307000__F3 | JNK signaling pathway regulates axonal transport and autophagy |
| PMC3307371__F8 | Exercise can increase small heat shock proteins (sHSP) and pre- and post-synaptic proteins in the hippocampus |
| PMC3307881__F5 | Inhibition of the Nedd8 system sensitizes cells to DNA Inter-strand crosslinking agents |
| PMC3307887__F1 | Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells. |
| PMC3307952__F7 | Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype |
| PMC3307959__F5 | Unconventional roles of kinesins in cell signaling |
| PMC3307977__F6 | Schematic diagram of the FGF2-STAT3-PAX3 signaling pathway |
| PMC3308137__F2 | miRNAs that promote or inhibit tumorigenesis provide diverse functions within oncogenic and tumor suppressor signaling pathways |
| PMC3308858__F8 | How GSK3B phosphorylation is involved with microtubule destabilization |
| PMC3308892__F4 | ER stress-associated miR-346 induction |
| PMC3309175__F7 | Mammalian target of rapamycin (mTOR) signaling pathway for the regulation of skeletal muscle protein synthesis in response to growth factors, nutrition, and mechanical stimuli |
| PMC3309495__F2 | Pathway analysis of altered metabolites upon paroxetine treatment |
| PMC3309723__F5 | Parp1 mediation of Sox2 activity in ESC pluripotency |
| PMC3309773__F1 | Regulation of ISGs by Akt1 and EMSY |
| PMC3309773__F7 | The functional role of Akt1, EMSY, and BRCA2 in the regulation of ISGs |
| PMC3309874__F1 | Insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS) is a major candidate pathway in human longevity |
| PMC3309939__F8 | Identification of a Novel Signaling Pathway and Its Relevance for GluA1 Recycling |
| PMC3309942__F1 | Interaction motifs and domains of RANKL signal intermediaries |
| PMC3309942__F2 | p62 in osteoclast signaling and protein trafficking |
| PMC3310050__F12 | Folate Decorated Dual Drug Loaded Nanoparticle: Role of Curcumin in Enhancing Therapeutic Potential of Nutlin-3a by Reversing Multidrug Resistance |
| PMC3310155__F1 | Model of CaS receptor sorting traffic |
| PMC3310197__F7 | Interactions of signaling by ER stress, oxidative stress, and cytokines with the pathways of autophagy: Induction of autophagy requires the assembly of Beclin-1 with class III PI 3 kinase (Vps34) and UVRAG |
| PMC3310225__F10 | Protein Kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development |
| PMC3310485__F4 | Schematic of the role of BDNF in the brain reward pathway associated with addiction |
| PMC3310713__F3 | Dual nature of Myc induced DDR |
| PMC3310792__F8 | Dengue Virus Infection Perturbs Lipid Homeostasis in Infected Mosquito Cells |
| PMC3310826__F16 | Schematic showing alterations to the TAG biosynthesis pathway in AS11 when DGAT1 activity is absent |
| PMC3310875__F6 | Progesterone Receptor Activates Msx2 Expression by Downregulating TNAP/Akp2 and Activating the Bmp Pathway in EpH4 Mouse Mammary Epithelial Cells |
| PMC3311240__F11 | Muscle cell signaling in response to 1E3 |
| PMC3311458__F5 | Diagram of ouabain/EO-activated, A2 Na+ pump/Src-mediated signaling cascade (the EO/A2 Na+ pump signalosome) |
| PMC3311515__F1 | Scheme for the intracellular renal RAS on the nuclear membrane |
| PMC3311926__F1 | Mitochondrial regulation of apoptosis |
| PMC3311998__F6 | Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate |
| PMC3312242__F1 | Regulation of cancer stem cells by inflammatory cytokine networks |
| PMC3312283__F2 | This figure shows three novel intracellular signaling pathways involved in the pathogenesis of IBD |
| PMC3312480__F1 | Schematic view of potential targets and site of action of some biologics in IBD |
| PMC3312677__F8 | Genetic pathways involved in the regulation of the Mesp2 pathway |
| PMC3312932__F2 | Regulation of the human catalytic subunit of telomerase (hTERT) |
| PMC3312985__F4 | Genes identified as part of the significant Para-ICA networks highlighted on a KEGG Alzheimer's pathway diagram derived from the DAVID functional association tool |
| PMC3312987__F2 | Commonly mutated pathways in glioblastoma |
| PMC3313080__F2 | Endoplasmic Reticulum Stress, the Unfolded Protein Response, Autophagy, and the Integrated Regulation of Breast Cancer Cell Fate |
| PMC3313452__F4 | The noncanonical NFKB pathway |
| PMC3313462__F4 | Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes |
| PMC3313594__F3 | Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery |
| PMC3313594__F5 | Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery |
| PMC3313666__F7 | Outline of the mevalonate pathway |
| PMC3313874__F2 | Networks built using differentially expressed genes in uninfected macrophages from C57BL/6 and CBA mice |
| PMC3313983__F5 | Associations between HIV and Human Pathways Revealed by Protein-Protein Interactions and Correlated Gene Expression Profiles |
| PMC3314429__F2 | miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma |
| PMC3314445__F9 | An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease-associated AB oligomers |
| PMC3314478__F1 | Parkinson's disease: don't mess with calcium |
| PMC3314482__F1 | Chk'ing p53-deficient breast cancers |
| PMC3314616__F2 | Methamphetamine Causes Differential Alterations in Gene Expression and Patterns of Histone Acetylation/Hypoacetylation in the Rat Nucleus Accumbens |
| PMC3314677__F9 | Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress in Human Prostate Cancer Cells by n-butylidenephthalide |
| PMC3314723__F6 | Pyruvate Protects Brain Against Ischemia-Reperfusion Injury by Activating Erythropoietin Signaling Pathway |
| PMC3314865__F3 | Targeting Mutant BRAF in Melanoma: Current Status and Future Development of Combination Therapy Strategies |
| PMC3315189__F1 | S-ADENOSYLMETHIONINE TREATMENT OF ALCOHOLIC LIVER DISEASE: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL |
| PMC3315209__F6 | Speculative model for the role of the Hippo pathway in germ cell tumorigenesis and reprogramming |
| PMC3315368__F4 | Gene Array Data from CWR22RV1 xenografts treated with PD325901 for three weeks |
| PMC3315421__F7 | C/EBP in neurite regeneration |
| PMC3315579__F4 | Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era |
| PMC3315606__F1 | Roles for prions and protein-only inheritance in cancer |
| PMC3315682__F1 | Serine biosynthetic pathway |
| PMC3315683__F1 | Phosphatidylinositol 3-kinase signaling pathway |
| PMC3316122__F2 | Schematic model depicting activation of the AIM2 inflammasome by F |
| PMC3316585__F1 | Formal Modeling and Analysis of the MAL-Associated Biological Regulatory Network: Insight into Cerebral Malaria |
| PMC3316754__F5 | Ingenuity pathway analysis was used to create a network of biologically relevant genes regulated in response to diet for comparisons control versus diet A, control versus diet B, and diet C versus diet B |
| PMC3316934__F4 | Significant differences in mRNA expression were seen for genes involved in the JNK signaling pathway between tumors arising in different CNS locations |
| PMC3316974__F1 | AKT-mTOR signaling pathway showing rapamycin inhibition sites in astrocytomas |
| PMC3317017__F4 | Altered signaling pathways and inhibitors |
| PMC3317163__F2 | One-carbon metabolism |
| PMC3317170__F1 | The activation of TLR2 by Leishmania sp., leading to a proinflammatory (left), or anti-inflammatory arm (centre and right) |
| PMC3317170__F3 | Proposed models for the activation of intracellular TLR9 and TLR3 by Leishmania |
| PMC3317177__F1 | New therapeutic approaches based on targeted biologic agents have generated great interest and are currently being investigated in several clinical trials focused on treatments for recurrent ovarian cancer () |
| PMC3317213__F4 | Metabolism of xenobiotics by cytochrome P450 pathway, and ribosome map views of identified proteins |
| PMC3317229__F2 | Structure of the ERK pathway (adapted from http://www.sabiosciences.com/) |
| PMC3317229__F3 | JNK signalling pathway (adapted from http://www.sabiosciences.com/) |
| PMC3317229__F4 | P38 signalling cascade (adapted from http://www.sabiosciences.com/) |
| PMC3317271__F1 | Simplified scheme of cell death and survival pathways involved in ALF |
| PMC3317440__F2 | Strain-specific host gene networks activated in Mtb-infected BMM |
| PMC3317641__F6 | Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes |
| PMC3317641__F7 | Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes |
| PMC3317991__F6 | RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer |
| PMC3318211__F1 | Signaling pathways involved in anthracycline-induced cardiomyocyte injury |
| PMC3318588__F8 | Subnetwork of functional interactions of ESRP-target networks |
| PMC3318612__F8 | Summary model of rAdV-sensing cascades in RAW 264.7 cell line |
| PMC3318683__F12 | A model of MMP-9 sorting and trafficking in activated macrophages |
| PMC3318742__F8 | Model of how RACK1 mediates activation of SHH/GLI signaling in NSCLC Cells |
| PMC3318965__F1 | Biology of Progesterone Receptor in the Normal Mammary gland and in Breast Cancer |
| PMC3319201__F3 | Primary therapeutic targets in the Ras downstream signaling pathway |
| PMC3319314__F3 | APE1 role in DNA base excision repair (BER) |
| PMC3319358__F1 | Gut triglyceride production |
| PMC3319358__F2 | Gut triglyceride production |
| PMC3319453__F2 | Insulin, IGF-I and IGF-II binding to IR and IGF-IR |
| PMC3319470__F1 | Coenzyme Q10biosynthetic pathway and electron transport role in the mitochondrial respiratory chain |
| PMC3319521__F1 | The CD47-SIRPA Pathway in Cancer Immune Evasion and Potential Therapeutic Implications |
| PMC3319745__F1 | Insulin signaling |
| PMC3319771__F2 | Convergence of miR-21 target genes and the apoptosis pathway |
| PMC3319919__F2 | Components of the TLR pathway and genes commonly induced during the innate immune response of zebrafish to bacterial infection |
| PMC3320662__F4 | ABHD6 is strategically positioned to regulate 2-AG levels at the site of its generation |
| PMC3320915__F7 | Model of proposed CCR7/CCL19 signaling pathway in T cells |
| PMC3320973__F8 | Wnt signaling regulation induced by cell surface HSPG desulfation during dentinogenesis |
| PMC3321152__F4 | Non-apoptotic functions of apoptosis-regulatory proteins |
| PMC3321211__F4 | Apoptotic cascade |
| PMC3321306__F1 | Gene expression network of the heritable transcripts in the nuclear factor kappa B signaling pathway |
| PMC3321383__F2 | Linking Lipids to Alzheimer's Disease: Cholesterol and Beyond |
| PMC3321453__F6 | Vitamin D pathway and sites of interaction with dietary factors |
| PMC3321461__F1 | Proposed mechanism for overcoming HNSCC resistance to EGFR antagonists using PI3kinase/Akt/mTOR and NFKB-IL6-STAT3 pathway inhibitors |
| PMC3321553__F2 | Coregulation of gene transcription by p53 and Smad complexes |
| PMC3321615__F1 | Canonical and noncanonical pathways of NFKB activation |
| PMC3321615__F2 | Chronic production of inflammatory mediators by microglial cells, particularly the generation of ROS and NO by activated microglia, mediates the majority of DA-neuronal degeneration and cell death |
| PMC3321808__F4 | Differential regulation of genes in the IL-10 pathway in neonates and school-age children with septic shock versus age-matched controls |
| PMC3321808__F5 | Differential regulation of genes in the antigen presentation pathway in neonates and school-age children with septic shock versus age-matched controls |
| PMC3322137__F3 | Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal Transition |
| PMC3322146__F8 | Role of miR-148a in Hepatitis B Associated Hepatocellular Carcinoma |
| PMC3322159__F8 | JC Virus T-Antigen Regulates Glucose Metabolic Pathways in Brain Tumor Cells |
| PMC3322224__F2 | cAMP Signaling CascadeLigand binding (represented in this example by PTH, but other ligands and receptors can stimulate cAMP synthesis), activates GsA and stimulates cAMP synthesis by adenylate cyclase |
| PMC3322338__F1 | Hypothetical model for neuroimmune-related actions of miRNAs in brain of human alcoholics (e.g., in microglia) |
| PMC3322527__F7 | TGFB signaling pathway overlaid with differentially expressed genes |
| PMC3322580__F4 | Enrichment and submodularization of cell cycle in terms of E3-mediated regulatory modules |
| PMC3322992__F8 | Pathways required for the role of CDCP1 in EGF/EGFR-induced cell morphological changes and increased cell migration |
| PMC3323126__F3 | Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus |
| PMC3323190__F7 | Summary of the effects of leptin in the hypothalamus of control (A) and ob/ob mice (B), as revealed by Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) and 13C High-Resolution-Magic Angle Spinning (HR-MAS) |
| PMC3323522__F7 | A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity |
| PMC3323563__F8 | Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2 |
| PMC3323758__F4 | DNA base excision repair: A mechanism of trinucleotide repeat expansion |
| PMC3323831__F1 | TLR signalling |
| PMC3323875__F3 | Feedback inhibition mediated by the PI3K/AKT/mTOR pathway |
| PMC3323898__F5 | Graphical representation of the known connections between the Wnt/Beta-catenin pathway and the Notch1 signaling pathways, according to the knowledge of the current literature |
| PMC3324026__F1 | Annotation of the insulin/TOR network in Apis showing methylated and differentially methylated genes |
| PMC3324133__F1 | Insulin receptor (INSR) belongs to a family of receptor tyrosine kinases that includes the receptor for insulin-like growth factor 1 (IGF-1R) |
| PMC3324360__F5 | Simplified TGFB pathway |
| PMC3324906__F1 | Pivotal role of E-cadherin, Beta-catenin, and transforming growth factor B (TGFB) and Wnt signaling pathways in an epithelial-mesenchymal transition (EMT) program |
| PMC3324922__F3 | ALDH1A1 pathway |
| PMC3324922__F4 | NOS3 pathway |
| PMC3325001__F1 | Hh signaling pathway |
| PMC3325001__F2 | Modes of Hh pathway signaling |
| PMC3325226__F3 | A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study |
| PMC3325426__F1 | The miRNA biosynthesis pathway from the nucleus to the cytosol |
| PMC3326558__F8 | Schematic illustrating estrogen-dependent regulation of miRNA (miR)-34b expression, its target genes and tumor growth |
| PMC3326643__F2 | Targeting Mnks for Cancer Therapy |
| PMC3326645__F6 | Ras inhibition by FTS attenuates brain tumor growth in mice directly and by enhancing reactivity of cytotoxic lymphocytes |
| PMC3327653__F1 | Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway |
| PMC3327724__F1 | Heroin metabolic pathway in humans |
| PMC3327812__F7 | Protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of GPS2 |
| PMC3328211__F2 | Arterial-venous and lymphatic specification in vertebrate embryo |
| PMC3328216__F1 | CCM3 interacts with multiple signaling complexes |
| PMC3328281__F1 | Molecular changes of serous carcinogenesis |
| PMC3328302__F7 | Schematic diagram illustrating the proposed interaction between CDH17 and Wnt/Beta-catenin pathway during HCC progression |
| PMC3328335__F2 | Scheme showing the essential functions of Notch in blood and vascular cell types (a) Osteocyte Dll/Jag-induced Notch signaling in hematopoietic stem cells (HSCs) is involved in their generation and self-renewal in the adult |
| PMC3328452__F8 | Identification of Protein Networks Involved in the Disease Course of Experimental Autoimmune Encephalomyelitis, an Animal Model of Multiple Sclerosis |
| PMC3328609__F3 | Development of the Bile Ducts: Essentials for the Clinical Hepatologist |
| PMC3328638__F1 | Glucose, fatty acid (FA) and glutamine metabolic pathways |
| PMC3328674__F1 | Exercise-stimulated glucose uptake in skeletal muscle |
| PMC3328748__F11 | The molecular players involved in angiogenesis signalling mediated by the interaction of VEGF-A with VEGFR-2 |
| PMC3328790__F1 | TGFB signaling pathway and its integration with other major pathways that is likely to be involved in the pathogenesis of cardiovascular diseases in elderly patients |
| PMC3328827__F2 | Beyond inactivation of the MEN1 gene, additional mutations in other genes may be responsible for acceleration of tumor growth, thus involving a process of multistep tumorigenesis |
| PMC3328839__F6 | Proposed pathway |
| PMC3328890__F1 | ROS-dependent and -independent apoptosis induced by particulate pollutants |
| PMC3328893__F1 | Physiological and pathophysiological stimuli regulate tonicity-responsive enhanced binding protein (TonEBP) in diverse cell types |
| PMC3328896__F2 | Cbl-b functions as central gate keeper of T-cell activation |
| PMC3328908__F10 | Diagram of canonical actin cytoskeleton signaling pathway |
| PMC3328908__F9 | Diagram of canonical tight junction signaling pathway |
| PMC3329340__F3 | Simplified TOR signaling network with known Arabidopsis homologs in Italic writing |
| PMC3329512__F3 | The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism |
| PMC3329512__F4 | The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism |
| PMC3329512__F7 | The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism |
| PMC3329863__F1 | Corticostriatal long-term depression (LTD) |
| PMC3329953__F8 | mTOR pathway in aging |
| PMC3329985__F4 | Top Networks Associated With MK-801 Treatment Identified by Ingenuity Pathway Analysis |
| PMC3331679__F2 | mTOR signaling in growth control and disease |
| PMC3331705__F1 | Tumor suppressors and oncogenes in the Wnt pathway |
| PMC3331761__F4a | Concordance of Changes in Metabolic Pathways Based on Plasma Metabolomics and Skeletal Muscle Transcriptomics in Type 1 Diabetes |
| PMC3332287__F2 | Wnt signaling pathway participated in the activation of hepatic stellate cells |
| PMC33333__F2 | Role of the antioxidant response element and the transcription factor Nrf2 in chemoprevention |
| PMC3334407__F5 | Schematic model for inhibition of cell proliferation by EGCG analogs |
| PMC3334466__F1 | Duo/Cdc42 pathways |
| PMC3334516__F4 | TGFB signaling pathway members and potential pathway member LRG1 |
| PMC3334602__F10 | Putative signal transduction pathways regulating fruiting body development in C |
| PMC3334602__F7 | Cordycepin analogues and the C |
| PMC3334621__F7 | IsomiRs and miRNAs target similar biological pathways |
| PMC3334709__F4 | Tau neuroinflammatory cascade |
| PMC3334867__F5 | Inborn Errors of Human JAKs and STATs |
| PMC3334885__F1 | T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice |
| PMC3334963__F7 | Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing |
| PMC3334963__F8 | Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing |
| PMC3334999__F5 | Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation |
| PMC3334999__F6 | Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation |
| PMC3335081__F9 | Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation |
| PMC3335094__F3 | Mechanical Strain Regulates Osteoblast Proliferation through Integrin-Mediated ERK Activation |
| PMC3335376__F4 | Illustration of p53 TIAs in lymphocytes |
| PMC3335376__F8 | Therapeutic modulation of the TP53 pathway |
| PMC3335396__F1 | Ligand-dependent activation of the Hh pathway |
| PMC3335670__F3 | Action of the enteropathogenic yersiniae Ysc T3SS effectors (Yops) on host cell signaling and survival |
| PMC3335800__F8 | MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells |
| PMC3335841__F2 | Reduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation |
| PMC3335841__F3 | Reduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation |
| PMC3335850__F1 | Gene Expression Analysis Implicates a Death Receptor Pathway in Schizophrenia Pathology |
| PMC3335938__F1 | Key therapeutic targets in the PI3K/Akt and MAPK pathways together with pharmacological agents inhibiting members of these signaling cascades |
| PMC3336023__F3 | Chronic alcohol exposure alters gene expression in HepG2 cells |
| PMC3336023__F4 | Chronic alcohol exposure alters gene expression in HepG2 cells |
| PMC3336066__F2 | Double-strand break repair in mammalian cells |
| PMC3336107__F1 | The Unfolded Protein Response in the ER |
| PMC3336361__F4 | Apoptosis pathways |
| PMC3336771__F1 | Endogenous polyamines potentiate macrophage polarization |
| PMC3337162__F2 | Polarization of migrating cortical neurons by Rap1 and N-cadherin |
| PMC3337163__F1 | Breaking up is hard to do |
| PMC3337621__F2 | Phosphoinositide 3-Kinase Signaling in Intestinal Inflammation |
| PMC3337681__F7 | Putative inhibitory pathway of inflammatory signaling events by CA |
| PMC3337715__F1 | Phosphoinositide-3 kinase signaling in cardiac hypertrophy and heart failure |
| PMC3337844__F1 | Autophagic proteins |
| PMC3337981__F8 | BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NFKB pathway |
| PMC3338086__F1 | Canonical and non canonical NF-kB pathways and related drugs inhibition |
| PMC3338129__F2 | Crosstalk Between Reverse Cholesterol Transport and Innate Immunity |
| PMC3338196__F3 | Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation |
| PMC3338341__F1 | Repressed (left) and activated (right) canonical HH signaling pathways |
| PMC3338341__F2 | Mechanisms of activation of HH signaling in hematological cancers |
| PMC3338536__F4 | TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators |
| PMC3338606__F6 | Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Toll-Like Receptor-4 and NFKB Signalling |
| PMC3338748__F1 | High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism |
| PMC3338780__F8 | Receptor Tyrosine Kinases Activate Canonical WNT/Beta-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct Beta-Catenin Phosphorylation |
| PMC3339861__F3 | EGF decreases sphingolipid biosynthesis transcripts |
| PMC3339861__F4 | EGF decreases free fatty acid (FFA) biosynthesis transcripts |
| PMC3339894__F2 | Putative molecular mechanisms of Wnt signaling, lipid metabolism, and IL-6 effects on insulin signaling in nonobese PCOS adipose tissue |
| PMC3340168__F13 | Apoptotic and necrotic targets modulate viability of epithelial responder cells by eliciting multiple recognition-dependent signaling pathways |
| PMC3340185__F5 | A model for the XIAP-regulated RhoGDI SUMOylation signaling pathway in modulation of cell motility |
| PMC3340193__F8 | Scheme to explain the increased production of HA in fro/fro (NSMase2-/-) mouse fibroblasts |
| PMC3340256__F1 | tBID structure and mechanism of action |
| PMC3340361__F1 | RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans |
| PMC3340364__F6 | Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells |
| PMC3340722__F2 | TNF related apoptosis-inducing ligand and its receptors in ocular tumors |
| PMC3341105__F2 | Signal transducer and activator of transcription 3 (Stat3) signaling |
| PMC3341446__F1 | Illustration of the PI3K pathway signaling pathway |
| PMC3341711__F1 | TGFB/Smad canonical signaling pathway |
| PMC3342043__F1 | TLR2 signaling |
| PMC3342049__F2 | Autophagy within antigen donor cells and cross-priming |
| PMC3342058__F2 | Major therapeutic targets for inhibition of donor-reactive memory T cell responses |
| PMC3342067__F4 | CD44 potentiates T cell activation, expansion, contraction, and maintenance of memory cells |
| PMC3342071__F2 | FcERI signaling events in WT, NTAL-/-, and LAT-/- cells |
| PMC3342110__F1 | Signaling pathways important for C |
| PMC3342334__F9 | Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway |
| PMC3342348__F1 | IL-1 signaling in the tumor microenvironment |
| PMC3342359__F1 | Three types of autophagy and cellular and molecular events in an autophagic pathway |
| PMC3342359__F2 | Autophagy induction by TLR stimulation |
| PMC3342364__F2 | Molecular mechanisms mediating the regulatory effects of hypoxia |
| PMC3342370__F1 | Role of autophagy during innate immunity |
| PMC3342401__F7 | Summary diagram of the proposed ADM signaling pathway in retina |
| PMC3342562__F6 | Schematic representation of the role of H2S in atherosclerosis |
| PMC3342643__F3 | Diacylglycerol kinases in immune cell function and self-tolerance |
| PMC3342643__F5 | Diacylglycerol kinases in immune cell function and self-tolerance |
| PMC3343040__F6 | Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease |
| PMC3343040__F7 | Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease |
| PMC3343135__F2 | Differential expression of mRNA and proteins encoding factors in the Notch signaling pathway |
| PMC3343154__F3 | Mammalian unfolded protein response (UPR) pathways |
| PMC3343200__F5 | IL-6 contributes to a positive feedback cycle of growth and invasion between CAFs (myofibroblasts) and its underlying tumor (afferent pathway) and between invading tumor and the recruitment of fibroblasts to myofibroblasts (efferent pathway) |
| PMC3343318__F6 | PLC signaling in B cells |
| PMC3343650__F5 | Three major signaling pathways are altered in prostate cancers |
| PMC3343703__F1 | Heme metabolism |
| PMC3344210__F4 | The effects of curcumin on the TNFA receptor and its downstream signaling pathway |
| PMC3344687__F7 | Schematic diagram of the Heme/TLR4/MyD88 and/or TRIF hypothesis in ICH |
| PMC3344904__F1 | High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery |
| PMC3345192__F1a | MYC on the Path to Cancer |
| PMC3345255__F1 | MAPK/ERK signaling and the hallmarks of cancers |
| PMC3345303__F2 | Neural and Cellular Mechanisms of Fear and Extinction Memory Formation |
| PMC3346111__F7 | Overall scheme of hypothetical effect of endocannabinoid signaling in human melanocytes |
| PMC3346695__F2 | Cell signaling pathways involved in ischemic postconditioning |
| PMC3346698__F5 | The main chain path of pheromone response pathway (b) the assembly paths detected by Scott et al |
| PMC3346698__F8 | One of the KEGG prostate cancer pathways (b) the paths detected by our method |
| PMC3346900__F4 | (A, B) Schematic view of the Fas/Fas-ligand (FasL) apoptotic signaling pathway |
| PMC3346964__F1 | Four major molecular pathways activated by tyrosine kinase receptor B (TrkB) and IGF-1 receptor (IGF-1R) |
| PMC3346990__F3 | The potential molecular mechanisms of crosstalk between nuclear receptors LXR and FXR-SHP-LRH-1 regulatory cascade in the liver and intestine |
| PMC3347034__F3 | Inhibition of type I IFN signaling by DENV: IFNA/B binds the type I IFN receptor (IFNAR), which is composed of IFNAR1 and IFNAR2 and is found on the surface of nucleated cells |
| PMC3347317__F2 | Modulation of type I IFN production by PRRSV |
| PMC3347452__F7 | Proposed model of SubAB-induced PERK-mediated apoptosis signaling pathway in HeLa cells |
| PMC3347554__F16 | The reversed retro –pathway for nucleoside synthesis beginning with Gla–3P and acetaldehyde was studied by J |
| PMC3347988__F4 | Schematic overview of the pathway controlling translational changes in adipogenesis |
| PMC3348077__F7 | Signaling pathway for the cytoprotective effect of STI571 in TRAIL-treated colon cancer cells |
| PMC3348384__F1 | miRNAs and estrogen action |
| PMC3348393__F1 | Cellular Senescence and Cancer Chemotherapy Resistance |
| PMC3348440__F1 | Target-derived NGF mediates axon growth and synapse assembly in sympathetic neurons via endocytic signaling mechanisms |
| PMC3348497__F1 | Insulin-like growth factor (IGF)-1 signal transduction |
| PMC3348846__F2 | Leukocyte recruitment to sites of injury/infection: dominant role of ROS |
| PMC3348846__F3 | Role of Rac1/RhoA balance in endothelial barrier integrity: impact of ROS and NO |
| PMC3348964__F1 | Metabolic pathway for disulfiram in humans |
| PMC3348998__F1 | Lipids and Prostate Cancer |
| PMC3349255__F7 | Schematic diagram of a cross-regulation network between FOXA1 and the ErbB2 signaling pathway in ER-negative breast cancer |
| PMC3349304__F6 | Identification of transcripts and proteins associated with hemocytes |
| PMC3349338__F1 | Metabolic pathway of protopanaxadiol ginsenosides in ginseng by intestinal microbiota |
| PMC3349963__F1 | Canonical and non-canonical IL-13 signaling in cells |
| PMC3349966__F1 | EIF4F-signaling pathway |
| PMC3350083__F1 | Overlap in FcERI, FcGRIII, and FcGRIIB signaling |
| PMC3350790__F1 | Dmrt genes integrate sex-specific, spatial, and temporal cues to induce sexually dimorphic differentiation in restricted groups of cells |
| PMC3350847__F2 | Canonical Wnt pathway |
| PMC3350990__F2 | Bioinformatic analysis of the differentially expressed proteins.The list of the MS-identified protein spots from 2D-DIGE was subjected to String (v |
| PMC3350994__F2 | The Bad, the Good, and the Ugly about Oxidative Stress |
| PMC3351101__F2 | Regulation of cytoplasmic mRNA decay |
| PMC3351275__F3 | Negative feedback and adaptive resistance to the targeted therapy of cancer |
| PMC3351290__F10 | TRPC1 channel is a major regulator of EGFR signaling |
| PMC3351343__F6 | Working model for onset of emphysema in Fut8+/- mice upon exposure to CS |
| PMC3351347__F7 | Control of Pax3 expression in the caudal neurectoderm via NCE2 |
| PMC3351834__F2 | Transcriptional changes in TGFB1 signaling pathway |
| PMC3352318__F4 | Association of cytoplasmic peptidyl Cys with functional networks according to reduction and oxidation of Cys residues |
| PMC3352318__F6 | Association of nuclear peptidyl Cys with functional networks according to reduction and oxidation of Cys residues |
| PMC3352318__F7 | Association of mitochondrial peptidyl Cys with functional networks according to reduction and oxidation of Cys residues |
| PMC3352961__F3 | Brain, blood, and iron: Perspectives on the roles of erythrocytes and iron in neurodegeneration |
| PMC3353386__F5 | NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways |
| PMC3353643__F6 | Proposed model of WNK4 signaling pathway mediating NCC regulation in DCT |
| PMC3353781__F8 | Signaling pathways mediating Beta-adrenergic effects on the cardiac microtubule network |
| PMC3353888__F1 | Adrenergic Alpha-1 Pathway Is Associated with Hypertension among Nigerians in a Pathway-focused Analysis |
| PMC3354586__F3 | Ingenuity pathway analysis (IPA) identified critical expression networks containing genes that are significantly correlated with the extent of necrosis in The Cancer Genome Atlas (TCGA) glioblastoma (GBM) samples from all subclasses (A and B) |
| PMC3355325__F2 | Two distinct DC semi-maturation pathways induce different types of regulatory T cells |
| PMC3355540__F2 | Nuclear receptors and photoreceptor differentiation in mice |
| PMC3355730__F2 | Co-expression of genes involved in lignin formation across species |
| PMC3355838__F1 | Step model of thyroid carcinogenesis |
| PMC3355838__F2 | Genetic events involved in thyroid tumor initiation and progression |
| PMC3355838__F3 | Wnt signaling pathways |
| PMC3355893__F1 | Vitamin D synthesis |
| PMC3355898__F2 | Somatic alterations in the PI3K pathway in prostate cancer |
| PMC3355926__F1 | Activation of the Pi3K/Tor pathway by insulin and glutamate |
| PMC3355930__F1 | Prostaglandin E2 (PGE2) biosynthesis and signaling |
| PMC3355932__F2 | Anaplastic lymphoma kinase signaling |
| PMC3355940__F2 | K63-linked polyubiquitination in the activation of canonical and non-canonical NFKB signaling pathway |
| PMC3355960__F1 | The cross-talk between extracellular and intracellular progesterone signaling pathways in female reproductive behavior |
| PMC3355967__F1 | Schematic of exosome secretion in a cancer cell model |
| PMC3355968__F1 | Regulation of FOXO3 and Beta-catenin by AKT, ERK, and IKK signaling pathway |
| PMC3355968__F2 | Regulation of Mcl-1 and Snail by AKT, ERK, and IKK signaling pathway |
| PMC3356006__F2 | Central regulation of leptin signaling, autonomic innervation of the adipocyte and Beta-cell, and the starvation response |
| PMC3356019__F1 | Emerging pharmacological strategies for CSCs targeting include self-renewal pathway antagonists and chemoresistance-reverting agents |
| PMC3356053__F10 | Most significant canonical pathway from this study |
| PMC3356061__F2 | Molecular pathway of activation of autophagy |
| PMC3356073__F1 | Phosphatidylinositol 3-kinase (PI3K) signaling cascade |
| PMC3356080__F4 | Factors and molecular mechanisms that influence ecdysone synthesis and the timing of critical weight attainment |
| PMC3356111__F9 | Schematic representation of TNF's dual effect on rat pinealocytes |
| PMC3356120__F3 | Pathway of steroid synthesis in the rat hippocampus |
| PMC3356304__F6 | Personalized Pathway Enrichment Map of Putative Cancer Genes from Next Generation Sequencing Data |
| PMC3356354__F10 | High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes |
| PMC3356354__F8 | High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes |
| PMC3356354__F9 | High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes |
| PMC3356574__F3 | The signaling pathways regulating radiation-induced bystander effects through expression and secretion of soluble biologically active factors |
| PMC3356623__F6 | Influence of Tc-axin and Tc-pangolin on canonical Wnt signaling and role of Wnt signaling in axis formation in the bilateria |
| PMC3356660__F1 | A model summarizing the results of the study in which the miR-301a molecule inhibits the PIAS3 enzyme, resulting in the promotion of the IL-6/23 receptor-STAT3 pathway and stimulation of Th17 differentiation |
| PMC3356707__F1 | Canonical WNT signaling pathway |
| PMC3356999__F1 | Fatty acid regulation of hepatic lipid metabolism |
| PMC3357406__F3 | Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development |
| PMC3357464__F3 | Scaffolds can organize pleiotropic kinases into stimulus-specific signaling modules to direct them to one specific pathway |
| PMC3357465__F1 | Gene mutations involved in PTC carcinogenesis |
| PMC3357504__F2 | Translation initiation control during growth factor stimulation, cellular stress, and cellular physiology |
| PMC3357504__F3 | Translation initiation control relays signals to erythroid and granulocytic differentiation |
| PMC3357548__F3 | TWEAK signaling pathway: illustration of the TWEAK signaling pathway as visualized in NetSlim web page |
| PMC3357552__F1 | Overview of TLR signaling |
| PMC3357552__F7 | TLR4 signaling in alcoholic steatohepatitis and fibrosis |
| PMC3357561__F5 | Gene expression by PPARs and inflammatory transcription factors: transactivation and transrepression mechanisms |
| PMC3358449__F1 | Key components in the regulation of methionine metabolism |
| PMC3358492__F1 | Emerging Therapies for Systemic Lupus Erythematosus - Focus on Targeting Interferon-alpha |
| PMC3358519__F1 | Schematic diagram of the cholinergic anti-inflammatory pathway (CAP) |
| PMC3358533__F5 | PPARA signaling canonical pathway in chronic arsenic-exposed lung epithelial cells |
| PMC3358876__F1 | H. pylori-induced miR-155 expression in macrophage immune cells |
| PMC3359066__F5 | Identification of Functional Differences in Metabolic Networks Using Comparative Genomics and Constraint-Based Models |
| PMC3359076__F5 | Regulation of thrombin-induced RelA/p65 nuclear translocation by the Rho-actin pathway |
| PMC3359119__F1 | mTORC1 signaling and regulation of pancreatic Beta-cell mass |
| PMC3359223__F1 | Glycolysis metabolic pathway |
| PMC3359641__F3 | Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors. |
| PMC3359655__F1 | Central IR/IGF-1 signaling |
| PMC3359724__F4 | Proposed model for how PARL regulates PINK1 localization under normal conditions and during stress |
| PMC3359728__F3 | Regulation of homeostatic AMPAR trafficking and turnover |
| PMC3359746__F1 | Several growth factor signals activate cell membrane receptor tyrosine kinases leading to activation of downstream interacting signal transduction pathways (PI3K/AKT, RAF/MAPK, and MTOR) |
| PMC3359829__F2 | Biosynthesis of resveratrol via the phenylalanine/polymalonate pathway |
| PMC3359833__F2 | Linking pathways to disease: Crohn's disease (from Wang et al |
| PMC3360095__F1 | P2X4R-p38 MAPK is a core signaling pathway through which spinal microglia and peripheral macrophages contribute to neuropathic pain and inflammatory pain |
| PMC3360100__F2 | Examples of signal transduction pathways in astroglial cells following P2X7R activation |
| PMC3360100__F3 | Examples of signal transduction pathways in astroglial cells following P2Y1R activation |
| PMC3360162__F2 | Antigen-mediated chemotaxis |
| PMC3360162__F4 | Synthesis of eicosanoids and their actions in mast cells |
| PMC3360606__F1 | Integrative Gene Regulatory Network Analysis Reveals Light-Induced Regional Gene Expression Phase Shift Programs in the Mouse Suprachiasmatic Nucleus |
| PMC3360882__F8 | Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals |
| PMC3360921__F8 | IQGAP1 regulates cell homeostasis through mTORC1 |
| PMC3360922__F1 | Murine mutants in the study of systemic iron metabolism and its disorders: an update on recent advances |
| PMC3361329__F2 | Signaling pathways of TNFAlpha-induced hepatocyte death |
| PMC3361414__F5 | Schematic representation of the interplay of T7 gp5.5, gp3, E |
| PMC3361581__F1 | Depiction of arachidonic acid signaling pathway highlighting genes measured in this study |
| PMC3361622__F4 | Recent developments on immunotherapy for brain cancer |
| PMC3361623__F1 | A New Framework for Understanding IRES-mediated Translation |
| PMC3361623__F3 | A New Framework for Understanding IRES-mediated Translation |
| PMC3361678__F1 | Many host factors are involved at each step of the HCV life cycle, which starts with virus binding to its specific receptors (CD81, CLDN1, OCLN, and SR-BI) |
| PMC3361682__F2 | UCB interaction with neural plasma membrane (A) and pathways by which UCB may affect neuronal function (B) |
| PMC3362209__F1 | RIP-1 in programmed necrosis |
| PMC3362297__F11 | Proposed roles of the calcineurin signaling cascade in stress responses, drug tolerance, and virulence in C |
| PMC3362516__F1 | Mitochondrial Ca2+ influx and efflux mechanisms |
| PMC3362922__F1 | Hexosamine biosynthetic pathway and its dependent processes |
| PMC3362995__F5 | The WNT10b and galanin-mediated signaling pathways linked to adipogenesis |
| PMC3362997__F10 | Competitive displacement of DMP1 by ASARM peptide modulates PHEX-DMP1-mediated FGF23 expression (see central osteoblast in green) |
| PMC3363007__F6 | The Antioxidant Mechanisms Underlying the Aged Garlic Extract- and S-Allylcysteine-Induced Protection |
| PMC3363966__F4 | Components and targets of pro-phenol oxidase, Toll-Dorsal/Dif and JAK/STAT pathways |
| PMC3364135__F1 | EpCAM and its potential role in tumor-initiating cells |
| PMC3364444__F1 | N-BPs may modulate myeloma progression through their effects on the mevalonate pathway and directly on MM plasma cells, bone marrow cells and immune cells in the bone marrow |
| PMC3364461__F1 | Multiple transduction mechanisms induced at the FSHR |
| PMC3364461__F4 | PI3K/mTOR signaling at the FSHR |
| PMC3364790__F4 | Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells |
| PMC3364883__F2 | Protein processing in endoplasmic reticulum is altered in Manf mutants |
| PMC3364883__F4 | Changes in gene expression related to endocytosis in Manf mutants |
| PMC3364883__F5 | Gene expression alterations in Manf mutants with a linkage to Parkinson's disease |
| PMC3364930__F5 | Subcellular localization of components of the PIWI-piRNA pathway and the proposed mechanism of TE suppression by this pathway |
| PMC3364993__F5 | Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes |
| PMC3365480__F1 | Pro- and anti-inflammatory effects of heat and heat shock proteins |
| PMC3365728__F9 | RANKL-induced actin ring organization in mature OCs |
| PMC3365794__F2 | Model showing arterial, venous, and lymphatic cell fate specification in the developing embryos |
| PMC3365799__F13 | Major steroidogenic pathways in the three zones of the human adrenal cortex |
| PMC3365812__F1 | Wnt/Beta-Catenin signaling pathway and their inhibitors |
| PMC3365812__F3 | Hh signaling pathway and their inhibitors |
| PMC3365841__F11 | Pituitary cells express GPCRs that engage the cAMP signaling pathway |
| PMC3365841__F16 | GPCR-modulated channel activity in pituitary cells |
| PMC3365861__F6 | Opposing roles of Myd88 and RAGE in extensive liver resection |
| PMC3366009__F8 | T cell signaling pathway used by A2 and A9 |
| PMC3366012__F2 | TNIP1-mediated signaling pathways |
| PMC3366440__F1 | Protective and pathogenic functions of Th17 cells |
| PMC3366472__F2 | TLR-4 signaling in cancer |
| PMC3366822__F7 | Schematic diagram showing the role of NDRG1 in inhibiting the EMT via regulation of the TGFB/SMAD and Wnt pathways |
| PMC3366852__F5 | Proposed mechanistic link between Por deletion and up-regulation of MHC II expression in enterocytes |
| PMC3366885__F1 | Signaling pathways involved in head and neck cancer |
| PMC3367549__F1 | FGF signaling cascades, an example of RTK signaling |
| PMC3367549__F2 | Canonical (left) and noncanonical (right) WNT signaling pathways |
| PMC3367549__F3 | Sonic hedgehog (SHH) signaling pathway |
| PMC3367549__F4 | BMP signaling pathway and regulation of SMAD activity |
| PMC3367552__F6 | Interaction map showing potential links between the Par proteins and components of the Hippo pathway |
| PMC3367558__F1 | Wnt signaling pathways |
| PMC3367558__F2 | Wnt signaling at vertebrate neuromuscular junctions |
| PMC3367558__F3 | Negative regulation of AChR clustering by Wnt3a |
| PMC3367714__F1 | ATM/ATR DNA-damage response pathway |
| PMC3367861__F1 | IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis |
| PMC3367861__F2 | IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis |
| PMC3367865__F3 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367865__F4 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367865__F5 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367865__F6 | Molecular Biology of Lung Cancer: Clinical Implications |
| PMC3367986__F2 | Comparative Genomic Analysis of Soybean Flowering Genes |
| PMC3368076__F6 | Proposed mechanisms of leptin and glucocorticoid stress hormones in the GSK3B/Beta-catenin signaling pathway |
| PMC3368236__F5 | Sema3E-PlexD1 signaling regulates pathway-specific synapse formation in the striatum |
| PMC3368264__F1 | An overview of the folate metabolism pathway in formation of essential intermediates in Leishmania |
| PMC3368374__F1 | In young muscle, abundant serum IGF-I can stimulate protein synthesis by activating Akt/mTOR/p70S6K pathway |
| PMC3368606__F2 | Assembly of targeting patches and inside–out orientation of the secretory pathway |
| PMC3368734__F7 | Functional interaction network analysis of genes with enriched expression (EE) and differential splicing (DS) in the placenta |
| PMC3368902__F1 | Postprandial Regulation of Hepatic MicroRNAs Predicted to Target the Insulin Pathway in Rainbow Trout |
| PMC3368918__F1 | Instrumental Variable Estimation of the Causal Effect of Plasma 25-Hydroxy-Vitamin D on Colorectal Cancer Risk: A Mendelian Randomization Analysis |
| PMC3368988__F2 | Sites of PP2A activity within the network of ERK activation |
| PMC3369606__F2 | Role of DCs in the pathogenesis of GVHD |
| PMC3369817__F8 | Pathway diagram of the cyanobacterial core metabolic network |
| PMC3369892__F8 | Summary diagram of the proposed adrenomedullin (ADM) signaling pathway in the retina |
| PMC3370224__F9 | The ARF6 signaling pathway involved in HLHCGR internalization as deduced from the present study |
| PMC3370249__F7 | Proposed FasL-Met signaling pathway |
| PMC3370283__F2 | Somatic Activating PIK3CA Mutations in CLOVES Syndrome(A) Demonstration of the PIK3CA c.1624G>A somatic mosaic mutation in participant CL4 |
| PMC3370396__F6 | NSAIDs perturbed genes related to thrombosis, fibrinolysis, and PAR signaling |
| PMC3370605__F1 | Roles of N-acetyl-l-glutamate synthase (NAGS) and of its homologous enzyme N-acetyl-l-glutamate kinase (NAGK) in arginine biosynthesis |
| PMC3370667__F1 | Schema of the FUS1 pathway |
| PMC3371005__F6 | Genome-Wide Association for Sensitivity to Chronic Oxidative Stress in Drosophila melanogaster |
| PMC3371699__F4 | miR-519d, miR-190, and miR-340 in the TGFB signaling pathway |
| PMC3372068__F1 | Coagulation and complement cascades |
| PMC3372091__F3 | Mechanisms underlying the biological effects of polyphenols |
| PMC3372214__F1 | Simplified schematic presentation of HCV genotype 2a-mediated blocking of the insulin signaling pathway |
| PMC3372250__F5 | The Hsp90 folding cycle |
| PMC3372268__F11 | Model depicting miR-155-mediated modulation of macrophage apoptosis |
| PMC3372318__F3 | The two major signaling cascades operating in cancer, following overactivation of the INSR/IGF-IR signaling pathways |
| PMC3372530__F2 | Diagram of genes that have been implicated in susceptibility to CL and ML disease caused by L |
| PMC3372896__F1 | Central role of Beta-catenin in Wnt signaling and the cadherin complex |
| PMC3372896__F3 | Intersection of pathways controlling Wnt/Beta-catenin signaling and cadherin-mediated adhesion |
| PMC3372917__F1 | PTPN11-Associated Mutations in the Heart: Has LEOPARD changed its RASpots? |
| PMC3372922__F2 | Action of TIEG in the TGFBeta-Smad signaling pathway |
| PMC3373577__F4 | Increased Levels of BAFF and APRIL Related to Human Active Pulmonary Tuberculosis |
| PMC3374082__F7 | Schematic representation of the data |
| PMC3374088__F1 | Caspase-8 has a crucial role in the regulation of DRs |
| PMC3374592__F1 | Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles |
| PMC3374768__F11 | Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury |
| PMC3374844__F1 | Three major UPR pathways in metazoans |
| PMC3374856__F3 | Mutations in glutamate signaling pathway and its associated proteins in melanoma |
| PMC3374974__F2 | EphA Receptor Signaling - Complexity and Emerging Themes |
| PMC3375057__F2 | Neurotrophins, the ERK MAP kinase signaling cascade, and GSK-3 |
| PMC3375273__F6 | TRAF-6 Dependent Signaling Pathway Is Essential for TNF-Related Apoptosis-Inducing Ligand (TRAIL) Induces Osteoclast Differentiation |
| PMC3375400__F1 | Comparison of the pathways responsible for the anti-apoptotic and pro-apoptotic effects of immune complexes containing oxidized LDL (oxLDL-IC) and malondialdehyde-modified LDL (MDA-LDL-IC) |
| PMC3375679__F2 | Environmental regulation of GSC proliferation at developmental stages of the gonad |
| PMC3375870__F1 | miR-23a, a critical regulator of "migR"ation and metastasis in colorectal cancer |
| PMC3375988__F7 | Schematic representation of the proposed roles of oleosin |
| PMC3376184__F3 | Function network built upon genes selected from the identified genetic component |
| PMC3376380__F1 | mTOR signaling and its regulation by DGKs |
| PMC3376383__F2 | Growth Control by Committee - Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling |
| PMC3376391__F2 | Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease |
| PMC3376408__F1 | IL-2 release by DCs stimulation of PRRs triggers the calcineurin/NFAT pathway via PLCG2 and intracellular Ca2+ flux |
| PMC3376449__F1 | HER2 signaling pathway |
| PMC3376488__F2 | T-cell development and differentiation |
| PMC3376488__F5 | MyD88 signal pathway |
| PMC3376488__F6 | TRIF signal pathway |
| PMC3376493__F4 | A Human Homeotic Transformation Resulting from Mutations in PLCB4 and GNAI3 Causes Auriculocondylar Syndrome. |
| PMC3376640__F6 | Proposed Model of Psoriasis Pathogenesis in the Presence of Psoriasis-Specific CARD14 AlterationsAfter an inflammatory trigger, alterations in CARD14 induce activation of NF-kB |
| PMC3376735__F1 | Logic of TGFB signalling from the membrane to nucleus |
| PMC3376735__F2 | Regulation of the TGFB-BMP receptor complexes by reversible ubiquitylation |
| PMC3376961__F1 | Annexin A2 pathway in pancreatic cancer invasion and metastasis |
| PMC3376977__F2 | NK cells sense tumors, course of disease and treatments |
| PMC3377006__F1 | Enhanced 15-lipoxygenase activity and elevated eicosanoid production in kidney tumor microenvironment contribute to the inflammation and immune suppression |
| PMC3377094__F2 | Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins |
| PMC3377280__F7 | Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition |
| PMC3377643__F2 | TGFB and Iron Differently Alter HBV Replication in Human Hepatocytes through TGFB/BMP Signaling and Cellular MicroRNA Expression |
| PMC3377831__F1 | Biosynthesis and catabolism of melatonin |
| PMC3378042__F2 | Implications of Protein Post-translational Modifications in IBD |
| PMC3378143__F3 | Inflammation and EMT: an alliance towards organ fibrosis and cancer progression |
| PMC3378544__F4 | Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells |
| PMC3378547__F5 | Molecular Effects of Doxycycline Treatment on Pterygium as Revealed by Massive Transcriptome Sequencing |
| PMC3378977__F1 | Summary of the suggested mechanism for the regulation of MMPs and TIMPs in the paracrine interplay between SCC-25 cells and fibroblasts |
| PMC3379693__F1 | Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut |
| PMC3379801__F8 | p16-Cdk4-Rb signaling pathway diagram |
| PMC3379883__F2 | Leptin and the CNS Control of Glucose Metabolism |
| PMC3379947__F1 | General scheme for the induction of Nrf2-signaling pathway |
| PMC3380091__F3 | Endometrial androgen target gene set |
| PMC3380218__F1 | The Drosophila IMD and mammalian TNF signalling pathways |
| PMC3380339__F1 | Cross-regulation between the IL-1B/IL-18 processing inflammasome and other inflammatory cytokines |
| PMC3380363__F1 | Oncogenic signaling pathways regulated by NO and PP2A |
| PMC3380376__F3 | Relationship between binding of ligands to the pattern recognition AGE receptor (RAGE) and inflammation, gene expression, oxidative and nitrosative stress, and damage to the macro- and microvasculature |
| PMC3380518__F1 | IL-33 signalling pathways |
| PMC3380573__F1 | Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment |
| PMC3380732__F7 | Analysis of the cell cycle pathway |
| PMC3381108__F2 | Unfolded protein response (UPR) |
| PMC3381230__F2 | Major mechanisms of immune modulation by tolerogenic DCs |
| PMC3381238__F1 | Schematic representation of APP processing and role of its products in AD pathology |
| PMC3381650__F3 | Signaling Networks of the Herpesvirus Entry Mediator (TNFRSF14) in Immune Regulation |
| PMC3381865__F6 | Proposed model for the role of the IGF-1R/NFKB signaling pathway in regulating the caspase-3 differentiation initiation signal |
| PMC3381938__F5 | Alternative Macrophage Activation and Metabolism |
| PMC3381956__F1 | Signaling pathways and their targeted therapies in NSCLC |
| PMC3382127__F7 | Toll-Like Receptor 3 and Suppressor of Cytokine Signaling Proteins Regulate CXCR4 and CXCR7 Expression in Bone Marrow-Derived Human Multipotent Stromal Cells |
| PMC3382204__F5 | Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease |
| PMC3382204__F6 | Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease |
| PMC3382204__F7 | Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease |
| PMC3382223__F2 | Ingenuity Pathway Analysis of altered expression of proinflammatory genes in normal human melanocytes |
| PMC3382223__F3 | Ingenuity Pathway Analysis of altered expression of proinflammatory genes in normal human melanocytes transduced with Ad-Slug |
| PMC3382229__F4 | Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis |
| PMC3382229__F5 | Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis |
| PMC3382253__F3 | Mitochondria are central organelles in determining cell fate in liver diseases |
| PMC3382253__F4 | Mitochondria biogenesis allows tissue adaption under stress |
| PMC3382265__F1 | Molecular network of protein degradation, amino acid metabolism, and behavior for NC-treated cells in comparison with TC extract-treated cells |
| PMC3382313__F1 | The role of Notch ligands in our models |
| PMC3382482__F1 | GFPT1-mediated MTOR signaling pathway affected by glucose and fructose in a pTr cell line |
| PMC3382540__F1 | ERK signaling pathway controls T-cell activation and anergy |
| PMC338270__F1 | Modification pathway of proteins for isoprenylation/methylation and effects of inhibitors of each enzymatic step |
| PMC338271__F1 | HDL enhances NO production by eNOS in vascular endothelium |
| PMC3382892__F2 | Th17 cells have stem cell-like features and promote long-term immunity |
| PMC3382911__F1 | Colon cancer cells produce immunoregulatory glucocorticoids |
| PMC3382968__F1 | The four principal manifestations of immunological autophagy |
| PMC3383194__F7 | The mechanism through which PTPN22 blocks proapoptotic and enhances antiapoptotic BCR signals |
| PMC33831__F1 | The branch of the flavonoid pathway for the synthesis of flavones in maize |
| PMC3383335__F1 | SnoN Signaling in Proliferating Cells and Postmitotic Neurons |
| PMC3383335__F2 | SnoN Signaling in Proliferating Cells and Postmitotic Neurons |
| PMC3383648__F1 | ismodegi |
| PMC3383804__F5 | HCMV management of the PI3K/AKT/mTOR pathway |
| PMC3383846__F2 | Signaling pathways that regulate cytokine AREs post-transcriptionally |
| PMC3383919__F1 | Schematic model of the Hippo signaling cascade in mammals |
| PMC3384069__F1 | Wnt/Beta-catenin signaling pathway |
| PMC3384380__F2 | Schematic depiction of NFKB signaling pathway highlighting FOXP1 target genes |
| PMC3384412__F2 | UPR signaling in diseases |
| PMC3384423__F1 | MTOR signaling pathway |
| PMC3384423__F4 | CRLs/SCF E3 ubiquitin ligases regulate mTOR pathway |
| PMC3384424__F1 | The mTOR signaling pathway |
| PMC3384717__F9 | Androgens up-regulating PCa cell proliferation via p66Shc-ROS signal pathway |
| PMC3385714__F3 | Paralvinella conceptual glutathione pathway and responses to thermal exposure |
| PMC3385949__F1 | FOXO proteins are involved in multiple signaling pathways that control cell proliferation, apoptosis, survival, and immune functions in response to external and internal stimuli |
| PMC3385961__F1 | Evolution of Wnt pathways |
| PMC3385990__F3 | Gp130 mediated IL-6 family of cytokines signaling pathway |
| PMC3386226__F8 | Rad4TopBP1 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner |
| PMC3386270__F8 | IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro |
| PMC3386525__F3 | The signalling transduction pathways involving the tuberous sclerosis proteins, hamartin and tuberin |
| PMC3386543__F7 | Schematic of C/EBP A/B functions in GCs |
| PMC3386597__F3 | AML Signalisome |
| PMC3386597__F4 | AhR-related signaling molecules are enriched within the AML Signalisome |
| PMC3387006__F7 | miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes |
| PMC3387006__F8 | miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes |
| PMC3387019__F7 | Cardiac Kallikrein-Kinin System Is Upregulated in Chronic Volume Overload and Mediates an Inflammatory Induced Collagen Loss |
| PMC3387493__F1 | Dual Aspects of Altered Bone Remodeling in Psoriatic Arthritis |
| PMC3387494__F3 | The regulatory network of EZH2 |
| PMC3387579__F1 | De novo DAG/TAG synthesis (Kennedy pathway) |
| PMC3387654__F1 | Mammalian Hippo pathway and cancer |
| PMC3387977__F3 | Targets for inhibition within the EGFR signaling pathway |
| PMC3388509__F2 | Inflammasomes and Intestinal Tumorigenesis |
| PMC3388569__F2 | Shared biological pathway activation between chemotherapeutic agent treatments |
| PMC3388569__F3 | Common biological pathways activated in OVCA cells in response to chemotherapeutic agents |
| PMC3388714__F2 | Layers of DC-mediated tolerance |
| PMC3388731__F5 | Canonical Hedgehog signaling |
| PMC3389016__F3 | Anti-Obesity Sodium Tungstate Treatment Triggers Axonal and Glial Plasticity in Hypothalamic Feeding Centers |
| PMC3389182__F1 | Transcriptome analysis of HeLa cells response to Brucella melitensis infection: A molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis |
| PMC3389589__F1 | Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target |
| PMC3390194__F1 | Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer |
| PMC3390208__F8 | Signaling pathway involving CaMKK regulation of GluA1 synthesis and synaptic incorporation as CP-AMPARs |
| PMC3390254__F1 | An emerging role of mTOR in lipid biosynthesis |
| PMC3390257__F2 | mTOR: from growth signal integration to cancer, diabetes and ageing |
| PMC3390419__F1 | Caspases and Kinases in a Death Grip |
| PMC3390457__F1 | Neuroprotective signaling pathways employed by Erythropoietin |
| PMC3390502__F8 | Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells. |
| PMC3390632__F1 | Overexpression of the Coq8 Kinase in Saccharomyces cerevisiae coq Null Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q6 Biosynthetic Pathway |
| PMC3390960__F1 | Formation of the COPII vesicle on the surface of the endoplasmic reticulum |
| PMC3390969__F2 | Impact of a negative regulator on pathogenesis and the development of sepsis, secondary to acute insults |
| PMC3391249__F8 | Defence Signalling Triggered by Flg22 and Harpin Is Integrated into a Different Stilbene Output in Vitis Cells |
| PMC3391329__F3 | Proteome coverage of the KEGG 'Insulin Signaling' pathway |
| PMC3391582__F2 | Signaling Circuitries Controlling Stem Cell Fate: To Be or Not To Be |
| PMC3391966__F1 | Model of hedgehog action in the fetal male reproductive system |
| PMC3392028__F1 | Transcription factors and signaling involved in the osteoblast differentiation pathway |
| PMC3392028__F3 | Seven important signaling networks of osteoblast differentiation |
| PMC3392049__F3 | An example pathway |
| PMC3392150__F1 | Unfolded protein response and its role in intestinal homeostasis and inflammation |
| PMC3392173__F1 | Wnt signaling pathways |
| PMC3392447__F2 | Routes of AMPAR trafficking |
| PMC3392647__F3 | Metabolic regulation of epigenetics |
| PMC3392648__F1 | Insulin signaling pathways |
| PMC3392816__F5 | Model for inhibitory effect of extracellular nicotinamide phosphoribosyltransferase on insulin-like growth factor-1 function in chondrocytes |
| PMC3393131__F1 | Wnt/Beta-catenin signaling in T cell immunity and cancer immunotherapy |
| PMC3393470__F1 | Chemical structures of PSI-352938 and its potential metabolites and the proposed metabolic pathway of PSI-352938 activation |
| PMC3393662__F8 | Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following FcERI Aggregation |
| PMC3393719__F8 | Yeast Magmas Ortholog Pam16 Has an Essential Function in Fermentative Growth That Involves Sphingolipid Metabolism |
| PMC3393821__F2 | Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: Preliminary findings |
| PMC3393825__F1 | Signaling the Mitochondrial Unfolded Protein Response |
| PMC3394120__F4 | Cytoskeleton remodeling signaling, an example of a differentially regulated pathway in the motor cortex of SALS |
| PMC3394417__F1 | Sample gene regulatory network |
| PMC3394505__F9 | Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas |
| PMC3394800__F4 | Developmental Changes in the Metabolic Network of Snapdragon Flowers |
| PMC3394800__F5 | Developmental Changes in the Metabolic Network of Snapdragon Flowers |
| PMC3394800__F7 | Developmental Changes in the Metabolic Network of Snapdragon Flowers |
| PMC3394947__F1 | The proteins involved in the different pathways related to eicosanoid biosynthesis |
| PMC3394958__F6 | Schematic showing observed protein level alterations in VSCC proteome in the context of HPV infection |
| PMC3394960__F10 | A schematic model for the role of ANXA2 in the pathogenesis of adenomyosis |
| PMC3395153__F1 | Roles of Platelets and the Signal Transductions Identified as the Major Cascades in Hepatocyte Proliferation |
| PMC3395736__F1 | Glycolytic pathway and its metabolic interconnection with the pentose-phosphate pathway |
| PMC3395887__F3 | Interaction of pathogen recognition and ST2 receptor systems with FcERI leads to substantial enhancement of production of cytokines and chemokines |
| PMC3395995__F1 | Alloantigen presentation via the direct, semi-direct and indirect pathways following organ transplantation, and (B) the relative intensity of each antigen-presentation pathway during the post-transplantation (post-Tx) period |
| PMC3396054__F3 | TGFB activates Smad 2/3 and Smad1 pathway |
| PMC3396155__F5 | The balance in signalling through either ALK-1 or ALK-5 regulates leptin expression in MSC |
| PMC3397239__F2 | Anaplasma phagocytophilum: deceptively simple or simply deceptive? |
| PMC3397315__F4 | Summary of ion channel targets of the GSK-3 pathway |
| PMC3397358__F1 | Viral genes and the activation of apoptosis |
| PMC3397482__F2 | Map of the VEGF signaling pathway (as an example of an important target in cancer therapy) obtained from KEGG is shown |
| PMC3397482__F4 | Cytoscape is an open-source bioinformatics software platform for visualizing molecular interaction networks and integrating these networks with other state data |
| PMC3397508__F1 | Possible molecular mechanisms of Ngb neuroprotection by modulating cell death/survival signaling pathways |
| PMC3397862__F7 | Schematic representation for the up-regulating mechanism of NSC proliferation by modulating Notch signaling with Lewis X-containing glycans in NSCs |
| PMC3397897__F8 | Schematic presentation of signaling pathways and their downstream targets that are affected by a feedback loop between hBVR and PKCD |
| PMC3397898__F6 | Signaling pathways that regulate cAMP-mediated WPB exocytosis |
| PMC3398046__F5 | MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Treatment with Steroids and Relationship with mRNA Targets |
| PMC3398118__F1 | Diagram of the pentose phosphate pathway showing substrates and enzymes involved in it |
| PMC3398238__F7 | A ubiquitin-binding protein FAAP20 links RNF8-mediated ubiquitination to the Fanconi anemia DNA Repair network |
| PMC3398464__F1 | Key branches of the insulin signaling cascade |
| PMC3398465__F4 | Systems analysis of salivary gland development and disease |
| PMC3398478__F1 | MAPK Pathways in S |
| PMC3398862__F2 | Cellular and molecular mechanisms of metformin: an overview |
| PMC3398916__F7 | The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network |
| PMC3399091__F1 | PAK1 Molecular Pathway |
| PMC3399249__F2 | Interactions between cytokine and glucocorticoid receptor (GR) signaling pathways |
| PMC3399377__F1 | Pathways leading to oxidative stress in PD and the modulation by PD-related genes |
| PMC3399380__F2 | IGF-IR signaling pathway |
| PMC3399428__F1 | “Hpo signaling pathway in Drosophila.” Schematic representation of Hippo kinases cascade and of its modulation by apical transmenbrame protein complexes |
| PMC3399428__F2 | "Hpo signaling pathway in Mammals and the cross-talk with RASFF1A signaling." Schematic representation of mammalian Hippo kinases cascade and interconnections between Hippo pathway and rassf1a protein signal |
| PMC3399530__F2 | Gene expression alterations in Rocky Mountain elk infected with chronic wasting disease |
| PMC3399969__F5 | State-of-the-science: An update on renal cell carcinoma |
| PMC3400831__F5 | PGI2signaling pathways in VSMCs |
| PMC3400941__F1 | Model depicting PI3K signaling |
| PMC3401455__F1 | Models for the repair of DNA double-strand breaks |
| PMC3401455__F2 | Rad51 filament formation and regulation |
| PMC3401681__F3 | Mesenchymal stem cells (MSCs) may have both growth inhibitory and stimulatory effects on tumours |
| PMC3401939__F1 | Targeting of oncogenes and miRNAs by retroviruses |
| PMC3401974__F2 | Mammalian target of rapamycin (mTOR) pathway regulates T-cell activation, differentiation and migration |
| PMC3402068__F1 | What Goes On Must Come Off: phosphatases gate-crash the DNA damage response |
| PMC3402097__F4 | Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF |
| PMC3402511__F4 | Novel MicroRNAs Differentially Expressed during Aging in the Mouse Brain |
| PMC3402681__F1 | Proposed mechanistic model on how SHARPIN regulates TNF-induced NFKB activation through linear ubiquitination-mediated mechanisms |
| PMC3402799__F2 | Networks generated by Ingenuity Pathway Analysis of the expression signature |
| PMC3403008__F3 | Regulation of TLS in replication-associated ICL repair |
| PMC3403084__F5 | Necrosis signaling pathways |
| PMC3403107__F8 | The molecular pathway regulating Xenopus lung development |
| PMC3403522__F2 | Intracellular HIF-1A regulation pathway in normoxia and hypoxia |
| PMC3403683__F1 | T cell receptor (TCR)-mediated signalling pathway |
| PMC3403823__F1 | TLR-induced corneal inflammation |
| PMC3403928__F4 | Caspase cascade |
| PMC3404043__F3 | Whole Transcriptome Analysis of the Effects of Type I Diabetes on Mouse Oocytes |
| PMC3404158__F2a | Ubiquitination and Phosphorylation in the Regulation of NOD2 signaling and NOD2-mediated Disease |
| PMC3404195__F6 | Proposed regulatory mechanism of ERB in colitis-associated colon cancer |
| PMC3404671__F6 | RyR-dependent signaling pathway that mediates PCB-induced and activity-dependent dendritic growth |
| PMC3404840__F1 | HIV pathogenesis and T-cell signaling by HIV-1 Nef |
| PMC3404840__F2 | Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef |
| PMC3404846__F1 | Mechanism of the tandem DRA/N-Boc protection proposed in this study based on the known pathway |
| PMC3404876__F2 | Identification of novel metastasis suppressor signaling pathways for breast cancer |
| PMC3405133__F3 | Identification of Pathway Deregulation - Gene Expression Based Analysis of Consistent Signal Transduction |
| PMC3405333__F10 | ERK/MAPK signaling pathway |
| PMC3405333__F11 | P38 MAPK signaling pathway |
| PMC3405333__F9 | Pathway component for cell cycle G2/M DNA damage checkpoint regulation |
| PMC3405730__F2 | IL-2 signals by activating three principal signaling pathways, the SHC/RAS/MAP kinase pathway, JAK1/JAK3/STAT5 pathway, and PI 3-K/AKT/p70 S6 kinase pathway |
| PMC3405739__F2 | The processes included in the insulin model |
| PMC3405855__F5 | Models of apoptosis-induced proliferation in mammals |
| PMC3405863__F4 | EGFR pathway in Drosophila |
| PMC3405863__F5 | Segmentation clock oscillator |
| PMC3405917__F1 | Wound repair and fibrosis |
| PMC3405917__F4 | EMT in fibrosis |
| PMC3406244__F3 | Thyroid Hormone Receptors and Cancer |
| PMC3406577__F6 | Restoration of cell death by ABT-737 in cancer cells that overexpress Bcl-2 and caspase activity is blocked |
| PMC3406594__F8 | Schematic model showing role of AMPKA1 as an upstream kinase of TAK1 in TLR4-mediated signaling pathway |
| PMC3406705__F8 | Hypothetical model elucidating the regulation of phosphorylated FAK expression through an integrin A5 and B1-mediated MEK-ERK1/2-dependent pathway after ESWT |
| PMC3406727__F1 | Simplified schematic drawing of metabolic pathways in Chlamydomonas reinhardtii (adapted from Ref |
| PMC3406917__F3 | Schematic Diagram of Matrix Protein Import into Peroxisomes.Cytosolic PEX5 and PEX7 recognize their cargo proteins (square and round shapes) via binding of specific targeting sequences, PTS1 and PTS2, respectively |
| PMC3407158__F9 | An NQO1-Initiated and p53-Independent Apoptotic Pathway Determines the Anti-Tumor Effect of Tanshinone IIA against Non-Small Cell Lung Cancer |
| PMC3407218__F5 | CXCL12/CXCR4 Axis Triggers the Activation of EGF Receptor and ERK Signaling Pathway in CsA-Induced Proliferation of Human Trophoblast Cells |
| PMC3407375__F3 | MicroRNA Circuits in Transforming Growth FactorB actions and Diabetic Nephropathy |
| PMC3407377__F2 | TGFB signaling via TAK1 pathway: Role in kidney fibrosis |
| PMC3407377__F3 | TGFB signaling via TAK1 pathway: Role in kidney fibrosis |
| PMC3407412__F3 | Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles. |
| PMC3407412__F5 | Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles. |
| PMC3407530__F5 | A simplified model for p80HT targeting the IL-10-Stat3 signaling pathway to promote plasma cell expansion and tumor development |
| PMC3407546__F8 | Proposed model for the pathway through which WSC induce inflammation in alveolar epithelial cells |
| PMC3407640__F8 | Summary of pathways with differentially expressed genes comparing sarcomas to MSC in the current study |
| PMC3407651__F1 | STAT3 signalling pathway in ALK+ ALCL |
| PMC3407651__F2 | MEK/ERK signalling pathway in ALK+ ALCL |
| PMC3407651__F3 | PI3K/Akt signalling pathway in ALK+ ALCL |
| PMC3407815__F1 | The interleukin (IL)-12/IL-23/interferon (IFN)G pathway and its role in mycobacterial disease control |
| PMC3408141__F8 | The molecular pathway required for NOD2-dependent autophagy |
| PMC3408193__F9 | Proposed protective pathway by E-LP against glutamate-induced apoptosis in RGCs |
| PMC3408195__F9 | A novel KRAS-initiated pathway leading to the activation of VMP1 in cancer cells |
| PMC3408345__F6 | Glucocorticoid (GC) actions in the airways epithelium |
| PMC3408425__F9 | Systems-level regulation of metabolic genes by Met TFs |
| PMC3408426__F10 | Metabolic genes regulated by the Met TFs |
| PMC3408431__F8 | RhoA GTPase Switch Controls Cx43-Hemichannel Activity through the Contractile System |
| PMC3408479__F8 | Endoplasmic Reticulum Stress Stimulates p53 Expression through NFKB Activation |
| PMC3408604__F1 | Cardiac myocyte signaling coupled to phosphodiesterase (PDE) 5 |
| PMC3408695__F1 | Part of the metabolic pathway of estradiol and the role of various enzymes involved: Estradiol is metabolized into 2-hydroxyestradiol (2-OHE2) and 4-hdroxyestradiol (4-OHE2) by CYP1A1 and CYP1B1 respectively |
| PMC3408740__F1 | Alarmins: awaiting a clinical response |
| PMC3408825__F1 | Autophagy pathway: signaling systems and three proposed membrane sources in autophagosome formation |
| PMC3409287__F3 | ITIM-mediated signaling function of IDO |
| PMC3409438__F2 | Broad receptor antagonism and attenuation of downstream signaling cascades mediated by decorin in tumor cells |
| PMC3409471__F2 | Clinical Implications of Cancer Stem Cell Biology in Hepatocellular Carcinoma |
| PMC3409633__F1 | TLR signaling controls transcription and mRNA half-life |
| PMC3410018__F5 | Immune cell types implied to be involved in celiac disease by pathway analyses |
| PMC3410226__F1 | Insulin signaling pathway |
| PMC3410255__F1 | Regulation of PTEN/PI3K/AKT pathway by microRNAs |
| PMC3410320__F1 | Survival and proliferative effects of Dilong extract on RSC96 Schwann cell |
| PMC3410437__F2 | KEGG pathway of the renin-angiotensin system |
| PMC3410580__F2 | Structure and interacting partners of p62/SQSTM1 |
| PMC3410580__F6 | p62/SQSTM1 acts either as a pro-oncogene or as a tumor suppressor protein |
| PMC3410583__F3 | Pathways of autophagy induction by hypoxia and mutant RAS |
| PMC3410636__F1 | Schematic illustration depicting a proposed effect of MeCP2 overexpression |
| PMC3410677__F9 | Schematic representation of potential interaction between the Rho GTPase signaling pathway, CTGF, and NMU in regulation of actomyosin-based contractile force and ECM protein profiles in TM cells |
| PMC3410756__F1 | Folate mediated one-carbon cycle |
| PMC3410851__F9 | Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System |
| PMC3411062__F1 | Network pathways analysis of molecules identified in T-cells that are involved in LFA-1/ICAM-1 signaling |
| PMC3411066__F6 | Formation and function of 16:1-PI in the signaling of the lipokine 16:1 in Swiss 3T3 cells |
| PMC3411424__F3 | Binary-relation notation and key molecules of AlzPathway |
| PMC3411424__F4 | AlzPathway on Payao system |
| PMC3411757__F1 | Modular Nature of Dendritic Cell Responses to Commensal and Pathogenic Fungi |
| PMC3411810__F6 | BRAFV600E Negatively Regulates the AKT Pathway in Melanoma Cell Lines |
| PMC3411916__F3 | [LM5]Strategies for treatment of traumatic central nervous system (CNS) injuries |
| PMC3411967__F1 | Cell-proliferative signaling pathways in lung tumors |
| PMC3412259__F1 | This diagram of BCR/CD19-initiated signaling shows two key outcomes of PI3K activation |
| PMC3412266__F1 | Atypical PKC signaling pathways leading to lymphocyte activation and/or differentiation |
| PMC3412276__F1 | Mannose metabolism in Trypanosoma brucei |
| PMC3412587__F1 | Ras signaling pathway which is disrupted in juvenile myelomonocytic leukemia (JMML) |
| PMC3412625__F6 | Combination therapy with VELCADE and tPA is neuroprotective in aged rats after stroke and targets miRNA-146a and the toll-like receptor signaling pathway |
| PMC3412720__F3 | JAK-STAT signaling pathway |
| PMC3412720__F4 | AKT signaling pathway |
| PMC3412960__F4 | Scheme of the Rho signaling canonical pathway identified in Ingenuity Pathway Analysis of the proteins with altered expression in both KO cell lines |
| PMC3412962__F4 | A, Differential expression of proteins involved in glycolysis and TCA cycle |
| PMC3412972__F2 | Proteins and protein isoforms in glycolysis/gluconeogenesis, TCA cycle, pentose phosphate pathway, galactose metabolism, and glutamine metabolism pathways |
| PMC3413017__F1 | Apoptosis and necrosis |
| PMC3413046__F2 | Integrated functional association analysis of protein and genetic interactions on alanine and aspartate |
| PMC3413220__F1 | LCAT functions potentially affecting the pathogenesis of cardiovascular disease |
| PMC3413225__F7 | Model describing the mechanisms of quercetin-induced cholesterol efflux in macrophages |
| PMC3413316__F1 | Protein C anticoagulant and cytoprotective pathways |
| PMC3413411__F1 | PI3K-AKT-mTOR signaling pathway |
| PMC3413921__F1 | Integration of intercellular signaling through the Hippo pathway |
| PMC3413998__F6 | Canonical Wnt signaling pathway |
| PMC3414384__F1 | Actin cytoskeleton as a sensor and mediator of apoptosis |
| PMC3414427__F3 | Schematic model showing the existence of distinct secretory pathways in pheochromocytoma |
| PMC3414439__F4 | Combinatorial Drug Discovery Using Transcriptional Response Modules. |
| PMC3414447__F6 | n-Butyl Benzyl Phthalate Promotes Breast Cancer Progression by Inducing Expression of Lymphoid Enhancer Factor 1 |
| PMC3414724__F1 | Major components of the PI3K pathway in B cells discussed in this review |
| PMC3414724__F2 | Role of the PI3K pathway in B cell antigen presentation functions |
| PMC3414724__F4 | Alterations in the PI3K pathway in malignant B cells |
| PMC3414727__F1 | AKT/mTOR signaling pathway |
| PMC3414727__F2 | AKT/mTOR signaling and crosstalk with glycolysis and mitochondrial oxidative phosphorylation |
| PMC3414739__F2 | LECA Rabs and their proposed functions |
| PMC3414811__F2 | Two branches of the unfolded protein response |
| PMC3414811__F3 | The mechanism of SLS |
| PMC3415084__F2 | Impact of placental insufficiency on endocrine responsiveness in fetal myoblasts and myofibers |
| PMC3415277__F6 | Identification of multiple disrupted components in a biological pathway |
| PMC3415586__F2 | Estrogen receptors regulate an inflammatory pathway of dendritic cell differentiation: mechanisms and implications for immunity |
| PMC3415708__F4 | A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer |
| PMC3415708__F5 | Novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer |
| PMC3416198__F8 | RANK-mediated osteoclast cytoskeletal organization |
| PMC3416387__F5 | Proposed metabolic pathways for central carbon and nitrogen metabolism in Y88 during glucose growth, based on protein identifications (dark gray ovals) and the presence of their corresponding genes in the Y88 genome |
| PMC3416606__F1 | Central carbon metabolism in S |
| PMC3416758__F7 | TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells |
| PMC3416961__F1 | Simplified diagram depicting Ras signaling and crosstalk with PI3 kinase- Akt pathway in leukemia |
| PMC3417062__F7 | Molecular mechanisms underlying PA and histologically anaplastic PA |
| PMC3417165__F1 | PI3K/AKT signaling pathway in Tregs |
| PMC3417337__F1 | Platinum drug action pathway |
| PMC3417348__F8 | Proposed role of ER calcium underlying early disruptions in synaptic homeostasis at the CA3-CA1 synapse in AD |
| PMC3417373__F4 | Signaling cascades that regulate the intrinsic and extrinsic pathways of apoptosis |
| PMC3417440__F1 | Cell death regulation: Signalling pathways and potential sites for pharmacological intervention |
| PMC3417476__F1 | Cyclic AMP-mediated induction of Treg cells and suppression of effector T cells |
| PMC3417478__F1 | Cyclic AMP elevation leads to induction of the SOCS-3 gene in VECs |
| PMC3417497__F6 | Schematic presentation of the signalling pathway involved in isoprenaline-induced up-regulation of IL-6 production in NMCFs |
| PMC3418056__F5 | Postulated interactions between 20-HETE and RAS in the vascular endothelium |
| PMC3418163__F1 | The two enzymatic pathways generating inorganic phosphate (Pi) as a result of LPA degradation |
| PMC3418323__F2 | Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor |
| PMC3418323__F4 | Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor |
| PMC3418323__F5 | Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor |
| PMC3418550__F1 | Pathways of SMX metabolism, bio-activation and detoxification, and pathway of GSH biosynthesis |
| PMC3418560__F5 | Schematic representation of a case of malignant myeloid disease evolving in four stages along one pathway |
| PMC3418637__F1 | Context-dependent effect of PI3K signaling on Treg development, differentiation and maintenance |
| PMC3418709__F1 | Hepatitis C, Porphyria Cutanea Tarda, and Liver Iron: An Update |
| PMC3418714__F1 | B-cell receptor signaling in CLL |
| PMC3418714__F2 | Integrin signaling in CLL |
| PMC3418714__F3 | Kinase inhibitors in CLL |
| PMC3418731__F3 | Signaling within the JAK-STAT pathway in bovine monocytes and M |
| PMC3418756__F6 | Immune activation in the GBS UTI transcriptome comprises prominent cytokine-cytokine receptor signaling |
| PMC3418847__F6 | Interaction Map for PTMScan Direct: Akt/PI3K pathway reagent |
| PMC3418849__F10 | TrkA signaling pathway |
| PMC3419095__F1 | Schematic presentation of the different mammalian MAP kinase pathways |
| PMC3419095__F2 | Molecular mechanisms of the pro- and anti-oncogenic properties of ERK3, ERK4, and MK5 |
| PMC3419137__F3 | Targets of the tumor suppressor gene miR-200 in regulation of the epithelial-mesenchymal transition in cancer |
| PMC3419258__F6 | Proposed model of FGF23 signaling in proximal tubular cells |
| PMC3419619__F8 | Protein kinase CD (PKCD) activation by proteolytic cleavage downstream of tumor necrosis factor (TNF) signaling in dopaminergic neurons |
| PMC3419804__F1 | Autophagy, Myocardial Protection and the Metabolic Syndrome |
| PMC3419830__F1 | Mechanisms of action for therapeutic agents in treating or preventing HAE |
| PMC3420349__F1 | P53 signaling pathway: In normal conditions (black arrows), p53 is maintained at very low levels |
| PMC3420817__F6 | 12-LIPOXYGENASE AND THE REGULATION OF HYPOXIA-INDUCIBLE FACTOR IN PROSTATE CANCER CELLS |
| PMC3420877__F8 | Celecoxib and GABA Cooperatively Prevent the Progression of Pancreatic Cancer In Vitro and in Xenograft Models of Stress-Free and Stress-Exposed Mice |
| PMC3420937__F6 | PTEN Negatively Regulates MAPK Signaling during Caenorhabditis elegans Vulval Development |
| PMC3421022__F1 | The prolactin signaling network in NetSlim |
| PMC3421049__F1 | Genomic Variation and Neurohormonal Intervention in Heart Failure |
| PMC3421055__F3 | IMPACT OF ALTERED METHYLATION IN CYTOKINE SIGNALING AND PROTEASOME FUNCTION IN ALCOHOL AND VIRAL-MEDIATED DISEASES |
| PMC3421232__F5 | Network of 25 target genes and their interactive genes involved in regulating apoptosis and autophagy |
| PMC3421730__F6 | The antiviral IFN response in infected THP-1 cells |
| PMC3422444__F1 | AIDing antibody diversity by error-prone mismatch repair |
| PMC3422444__F2 | AIDing antibody diversity by error-prone mismatch repair |
| PMC3422477__F1 | Apoptosis affects cell signaling pathways that control lipid synthesis and energy metabolism |
| PMC3422654__F1 | Genes Associated with Outcomes in the Context of Two Fatty Acid Metabolism Pathways |
| PMC3422784__F5 | Sensing the environment: Regulation of local and global homeostasis by the skin neuroendocrine system |
| PMC3423122__F10 | Transcriptome of genes encoding enzymes and proteins on the lactose synthesis pathway, including GLUT1, HK1, PGM1, UGP2, GALE, GALT, SLC35A2, LALBA, and B4-GALT1, -3, and -5 |
| PMC3423122__F11 | Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans. |
| PMC3423339__F7 | BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: Implications for Hereditary Hemorrhagic Telangiectasia Type II |
| PMC3423345__F2 | Early Second Trimester Maternal Plasma Choline and Betaine Are Related to Measures of Early Cognitive Development in Term Infants |
| PMC3423373__F3 | Transcriptional Programs Controlling Perinatal Lung Maturation |
| PMC3423475__F9 | Animal oral and veg1 ectodermal GRN for sea urchin embryogenesis |
| PMC3423502__F6 | Crosstalk between Fgf and Wnt signaling in the zebrafish tailbud |
| PMC3423541__F2 | Biological targets under investigation for treatment of SLE |
| PMC3423785__F2 | Functional analysis of the top-scoring network of AE9a dysregulated genes |
| PMC3423855__F1 | Hepatocellular processing of, and immune modulation by, the precore protein |
| PMC3423951__F1 | The interplay between pituitary hormones and main signaling pathways of the IGF system in thyroid, adrenal and ovary cancers |
| PMC3424007__F1 | Biological association network (BAN) of differentially expressed genes in common between CA and ICC |
| PMC3425078__F5 | Effects of NO and nitrosative stress on apoptosis |
| PMC3425429__F1 | Working model depicting some of the multiple signaling pathways that have been reported to modulate cell-cycle activation and/or proliferation in rodent Beta-cells |
| PMC3425519__F2 | Intracellular vascular endothelial growth factor (VEGF) signal transduction pathway |
| PMC3425523__F4 | Genes known to cause kidney cancer and their relationship with the mammalian target of rapamycin signaling pathway |
| PMC3425527__F1 | Hedgehog signalling |
| PMC3425856__F4 | CO prevents inflammatory responses via inhibition of NFKB signaling pathway |
| PMC3425950__F1 | Targeting a Common Collaborator in Cancer Development |
| PMC3425953__F1 | Activity of Wnt canonical signaling pathway in the normal and tumor cells |
| PMC3425953__F2 | The activity of the EGFR/KRAS signaling pathway in normal and tumor cells |
| PMC3425953__F3 | The activity of PI3K signaling pathway in normal and tumor cells |
| PMC3426114__F9 | Two Possible Models Regarding the Role of CDT1 Proteins in Response to DNA Stress.(A) Downregulation of CDT1 upon DNA stress may be promoted by WEE1 and/or SOG1 |
| PMC3426219__F2 | Chondroitin sulfate proteoglycan 4 (CSPG4) Signaling Pathways |
| PMC3426484__F1 | Asparagine N-Glycosylation pathway |
| PMC3426490__F2 | Flow chart showing the genes involved in TLR signaling pathway |
| PMC3426550__F6 | SCS3 and YFT2 Link Transcription of Phospholipid Biosynthetic Genes to ER Stress and the UPR |
| PMC3426783__F4 | IPA network analyses were applied to differentially expressed genes in mouse brain after in vivo ketamine exposure |
| PMC3426818__F5 | MUC5B gene expression is transcriptionally regulated by various mediators and pathways |
| PMC3426835__F5 | Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis |
| PMC3427140__F4 | Cross talk between focal adhesion kinase and cadherins: Role in regulating endothelial barrier function |
| PMC3427155__F2 | Analysis of Differential miRNA Expression in the Duodenum of Escherichia coli F18-Sensitive and -Resistant Weaned Piglets |
| PMC3427211__F3 | Microbes-induced EMT at the crossroad of inflammation and cancer |
| PMC3427262__F1 | Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease |
| PMC3427269__F1 | AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway |
| PMC3427396__F2 | Termination steps during IgE-mediated activation |
| PMC3427407__F1 | AB oligomers stimulate oxidative/nitrosative pathways involving NMDA receptor, nNOS and NADPH oxidase leading to production of ROS and activation of cPLA2 |
| PMC3427417__F7 | Nicotine-induced A7nAChR/JAK2 pathway in cooperation with nicotine-mediated ERK1/2 activation potentiates STAT3 activation in PC cells |
| PMC3427656__F1 | GH-STAT5 signaling pathway |
| PMC3427704__F1 | AID-associated gene network |
| PMC3427792__F1 | Akt isoforms and glucose homeostasis - the leptin connection |
| PMC3427795__F1 | Interplay between FOXO, TOR, and Akt |
| PMC3427885__F4 | Impact of HCV infection on ILK signaling |
| PMC3428061__F2 | Interface between hemostasis and adaptive immunity |
| PMC3428099__F1 | FAM83A and FAM83B: candidate oncogenes and TKI resistance mediators |
| PMC3428242__F1 | Simplified schematic representation of the mammalian target of rapamycin (mTOR) signaling pathway.Notes: Red, pathway inhibitor; Green, pathway activator; Blue, mTOR complex protein.Abbreviation: NOS, not otherwise specified |
| PMC3428307__F1 | Biosignatures for Parkinson’s Disease and Atypical Parkinsonian Disorders Patients |
| PMC3428335__F8 | Master Regulators in the Metabolic/Transcriptional Coupling in Breast Carcinomas |
| PMC3428377__F3 | Signaling pathways for estrogen production and action |
| PMC3428657__F1 | The signaling pathway ofGHRregulated by let-7b |
| PMC3428770__F2 | Signalling events activating PKB/Akt and cellular functions regulated by PKB/Akt |
| PMC3428775__F3 | Model depicting effects of Wnt-stabilized Beta-catenin through Tcf proteins in mESCs |
| PMC3429047__F5 | Simplified illustration of the canonical Wnt signaling pathway |
| PMC3429058__F1 | HDL promotes regression |
| PMC3429092__F4 | TRPC5-mediated feedback of Ca2+ and NO signaling in endothelial cells and attenuation of Ca2+ entry through TRPC6 by NO in smooth muscle cells |
| PMC3429121__F2 | Metabolic flux through the purine salvage pathway in L |
| PMC3429478__F1 | Development of Quinoxaline 1, 4-Dioxides Resistance in Escherichia coli and Molecular Change under Resistance Selection |
| PMC3429538__F5 | Highlights from this issue |
| PMC3429540__F1 | Emerging role of autophagy in kidney function, diseases and aging |
| PMC3429544__F8 | Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition |
| PMC3429585__F1 | DKK1 as a novel target for myeloma immunotherapy |
| PMC3429622__F4 | TRBP in the exogenous and endogenous RNAi pathways |
| PMC3429771__F5 | Opposing roles of FGF2 and BMP4 in directing TB formation from epiblast type ES cells and iPS cells and the need to exclude FGF2 from the growth medium to minimize the co-induction of mesoderm and endoderm |
| PMC3429879__F1 | Therapeutic Mechanisms of Treatment in Cervical and Vaginal Cancer |
| PMC3429940__F1 | Optimizing treatments for lymphangioleiomyomatosis |
| PMC3430113__F4 | Schematic depicting a central role for transforming growth factor (TGF)B1 signaling in osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis (LCH) |
| PMC3430120__F2 | Summary of pathways controlling muscle protein synthesis (MPS) and muscle protein breakdown (MPB) |
| PMC3430207__F3 | Molecular relational network of genes modulated by BaP in lung tissues enriched for cancer function using IPA for all three doses with p53 at the central node |
| PMC3430210__F1 | TRAIL signaling pathway and mechanisms of TRAIL resistance |
| PMC3430392__F1 | The function of CETP in RCT.Notes: CETP mediates the equimolar transfer of CE and TG between atherogenic VLDL, LDL, and anti-atherogenic HDL |
| PMC3430470__F5 | The role of Monosaccharide Transport Proteins in carbohydrate assimilation, distribution, metabolism and homeostasis |
| PMC3430547__F4 | TORC1 and nitrogen regulation |
| PMC3430718__F7 | SOCS1 regulates the IFN but not NFKB pathway in TLR-stimulated human monocytes and macrophages |
| PMC3430731__F1 | Signaling pathways regulating lipogenesis in cancer cells |
| PMC3431075__F1 | NFKB members and NFKB signaling |
| PMC3431500__F1 | Class I PI3K signal transduction pathway |
| PMC3431627__F7 | Mechanisms of acquired-resistance to vemurafenib |
| PMC3431702__F7 | TLR signaling and proposed model for DMF-mediated impairment of DC maturation |
| PMC3431801__F7 | Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases |
| PMC3431873__F2 | Generation of free radicals in aging and Parkinson’s disease (PD) |
| PMC3431883__F2 | Specific and non-specific mechanisms of oligodendrocyte injury |
| PMC3431883__F3 | Signaling mechanisms of oligodendrocyte injury |
| PMC3432059__F6 | Establishment of Mouse Teratocarcinomas Stem Cells Line and Screening Genes Responsible for Malignancy |
| PMC3432093__F11 | Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells |
| PMC3432146__F1 | Proline metabolic pathway |
| PMC3432190__F2 | Concept of molecular network in schizophrenia |
| PMC3432194__F2 | Epistasis network for WTCCC GWAS of bipolar disorder |
| PMC3432272__F1 | HIV's double strike at the brain. |
| PMC3432348__F1 | Pathways activating and inhibiting complement |
| PMC3432498__F1 | Activation of the IKK-NFKB pathway by radiotherapy and chemotherapy |
| PMC3432564__F2 | Transmembrane CLRs involved in antifungal immunity and their intracellular signaling pathways |
| PMC3432650__F1 | How does Lin28 let-7 control development and disease? |
| PMC3432651__F2 | Involvement of the target of rapamycin (mTOR) pathway in human disease syndromes |
| PMC3432767__F1 | Rac and RhoA signaling pathways during cytokinesis |
| PMC3432834__F2 | Two NFKB activation pathways induced by RANK, CD40, and LtB R signaling |
| PMC3433406__F5 | Large scale phosphoproteome analysis of LNCaP human prostate cancer cells |
| PMC3433899__F3 | Single gene and protein network generated by Approach 3 (Network 1) that demonstrated significance as a clinical relapse predictor following a stringent permutation based test |
| PMC3433902__F5 | Immune response to phagosome in antigen presentation network pathway map associated with the proteins identified as differentially regulated during zebrafish caudal fin regeneration |
| PMC3433910__F1 | Putative scheme of the cellular metabolism in the hydrogen producing arachaeon T |
| PMC3433920__F4 | Acute phase canonical pathway and corresponding acute phase reactants identified as significant for interaction effect |
| PMC3433932__F3 | The scheme summarizes the stretch-induced pathway that allows ROS scavenging in response to mechanical stimuli |
| PMC3434202__F1 | Suppression of Cancer Progression by MGAT1 shRNA Knockdown |
| PMC3434281__F6 | Proposed model for attenuation of canonical TGFB SMAD and activation of non-canonical TGF-Beta-NFKB signaling pathways in HNSCC |
| PMC3434350__F1 | Translational impact of the mTOR signaling pathway |
| PMC3434475__F1 | The canonical translation pathway in eukaryotes with the ribosomal recycling and initiation phases shown in detail |
| PMC3434621__F5 | Interactions of Rex with host pathways, uncovered and covered |
| PMC3434988__F1 | Hepatocyte growth factor (HGF)-cMET axis signaling network and ongoing targeted therapy strategies |
| PMC3435197__F2 | Spectrum of somatic mitochondrial mutations in five cancers |
| PMC3435458__F7 | RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells |
| PMC3435478__F2 | Age-related alterations in receptors and signaling molecules of CD8 T cells |
| PMC3436147__F8 | Putative mechanisms of the effect of the Kv1 |
| PMC3436188__F8 | Interaction between Ryk and Wnt signaling pathways |
| PMC3436227__F2 | MyD-88 dependent TLR signaling pathway |
| PMC3436276__F7 | Model illustrates proposed two pathways of regulation of S100A4 mediated by HBXIP |
| PMC3436686__F6 | Ensemble representation of EGF signalling network |
| PMC3436816__F2 | EnrichNet: network-based gene set enrichment analysis. |
| PMC3436837__F1 | Boolean network model of the HGF-induced keratinocyte migration |
| PMC3437205__F3 | Pathway analysis of the hypermethylated genes in lymph node metastasis including their biological processes and association to breast carcinogenesis and neoplasm metastasis |
| PMC3437319__F2 | Regulation of mammalian target of rapamycin complex (mTORC) signaling networks |
| PMC3437536__F1 | Class I phosphoinositide-3-kinase (PI3K) signaling pathway |
| PMC3437546__F2 | HIF target genes encode proteins involved in critical aspects of cancer progression |
| PMC3437636__F2 | Formation of the NFKB-stimulating TNFR1 signaling complex |
| PMC3437743__F1 | Glutathione and modulation of cell apoptosis |
| PMC3437941__F1 | Integration of B cell responses through Toll-like receptors and antigen receptors |
| PMC3437946__F8 | Synthesis and degradation of dopamine, norepinephrine, and serotonin |
| PMC3438084__F6 | A subset of the up-regulated genes with known function in response to maize root exudates |
| PMC3438135__F1 | Altered pancreatic beta cell mechanism silencing alpha and delta cells |
| PMC3438185__F9 | Novel Levamisole Derivative Induces Extrinsic Pathway of Apoptosis in Cancer Cells and Inhibits Tumor Progression in Mice |
| PMC3438338__F7 | Interferon-Gamma-induced glial cell activation by transforming growth factor B1: A role for STAT1 and MAPK pathways |
| PMC3438361__F2 | Illustration of the metabolic pathway analysis for zidovudine with thick arrows indicating targets identified by the automatic classifier |
| PMC3438665__F1 | p53-dependent and -independent therapeutic strategies for cancer cells |
| PMC3438932__F7 | The role of dimeric TIR platform for the inhibition and activation of MyD88 signaling pathway |
| PMC3439122__F1 | Effects of statin on mevalonate pathway |
| PMC3439136__F2 | TAP-MS PPI RTK-Ras-ERK signaling network |
| PMC3439136__F3 | Additional analysis of the PPI network |
| PMC3439136__F4 | Dynamics in the RTK-Ras-ERK signaling network |
| PMC3439334__F5 | WNT signalling pathway map enriched with genes up-regulated in tumorgraft-forming tumors |
| PMC3439334__F6 | Immune response pathway map enriched with genes down-regulated in the tumorgraft forming patient tumors |
| PMC3439567__F2 | P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation |
| PMC3439646__F1 | Complement and dysbiosis in periodontal disease |
| PMC3439829__F4 | Diverse cohesinopathy phenotypes |
| PMC3439854__F2 | Transcriptional regulation of PDPN expression |
| PMC3439965__F3 | Simplified overview of the canonical Wnt signaling pathway |
| PMC3440368__F7 | Disturbed Relaxin Signaling Pathway and Testicular Dysfunction in Mouse Offspring upon Maternal Exposure to Simazine |
| PMC3440872__F4 | Model showing a role for Yap in governing cardiac growth and survival by interlinking the Hippo, IGF, and Wnt pathways |
| PMC3441179__F4 | microRNAs Shape the Neuronal Landscape |
| PMC3441384__F4 | Nanoparticle-induced autophagy |
| PMC3441633__F9 | A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2B) Regulation |
| PMC3441782__F6 | Molecular network of downregulated genes in U373MG cells following exposure to ET-770, the compound 1a |
| PMC3441782__F7 | Molecular network of upregulated genes in U373MG cells following exposure to ET-770 derivative, the compound 3 |
| PMC3442422__F1 | The Sre1 regulatory pathway |
| PMC3442575__F4 | Genes Involved in the Calvin Cycle and Photorespiration.(A) Schematic of the Calvin cycle and photorespiration pathway in C |
| PMC3442742__F1 | NGF signaling pathways in mediating neurotrophic and nociceptor effects.Notes: NGF signals through the high-affinity TrkA and low p75NTR receptors |
| PMC3442804__F2 | Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter |
| PMC3442837__F1 | Regulation of phenotypic transitions in the fungal pathogen Candida albicans |
| PMC3442865__F1 | TOR pathway activation |
| PMC3442876__F2 | Autophagy in immunity |
| PMC3442893__F1 | Proline dehydrogenase (oxidase), a mitochondrial tumor suppressor, and autophagy under the hypoxia microenvironment |
| PMC3442981__F1 | Metabolic pathways for 2,3-butanediol biosynthesis and pyruvate metabolism in S |
| PMC3443126__F7 | H2O2-modulated permeability increase and cytoskeleton reorganization via MARCKS phosphorylation in endothelial cells |
| PMC3443185__F1 | Two mechanisms underlying circadian control of NFKB response |
| PMC3443208__F4 | Prenatal Exposure to TCDD Triggers Significant Modulation of microRNA Expression Profile in the Thymus That Affects Consequent Gene Expression |
| PMC3443258__F6a | An inventory of peroxisomal proteins and pathways in Drosophila melanogaster |
| PMC3443512__F8 | TARGETING THE eIF4A RNA HELICASE BLOCKS TRANSLATION OF THE MUC1-C ONCOPROTEIN |
| PMC3443855__F7 | Nodal Signaling via an Autocrine Pathway Promotes Proliferation of Mouse Spermatogonial Stem/Progenitor Cells through Smad2/3 and Oct-4 Activation |
| PMC3443857__F1 | Progesterone regulated paracrine signaling model depicted within the uterine compartments at the time of embryo implantation |
| PMC3443885__F3 | Molecular interaction between estrogen and thyroid hormone |
| PMC3444139__F3 | NFKB signaling pathway in ATL |
| PMC3444148__F1 | Nodal signaling pathway in melanoma |
| PMC3444437__F9 | C-srcregulating primordial follicle activation and growth through PI3K →PKC →MAPK signaling pathway |
| PMC3444501__F4 | Therapeutic Effects of Astragaloside IV on Myocardial Injuries: Multi-Target Identification and Network Analysis |
| PMC3444627__F1 | Cytokine Combination Therapy Prediction for Bone Remodeling in Tissue Engineering Based on the Intracellular Signaling Pathway |
| PMC3444684__F1 | Epigenetic rejuvenation bypasses the ES/iPS cell stage |
| PMC3444692__F2 | ATF-2 is a nuclear target of p38/Jun N-terminal protein kinase (JNK) |
| PMC3444914__F1 | The DNA base excision repair (BER) pathway |
| PMC3445042__F7 | The role of Wnt signaling in hypothalamic progenitor differentiation |
| PMC3445581__F2 | Transcriptional Differences between Rhesus Embryonic Stem Cells Generated from In Vitro and In Vivo Derived Embryos |
| PMC3445623__F2 | Gene Expression and Functional Annotation of the Human Ciliary Body Epithelia |
| PMC3445701__F7 | Alzheimer's Disease pathway from KEGG |
| PMC3445776__F1 | The Hedgehog signaling pathway |
| PMC3446326__F1 | Alterations in the FGFR signalling pathway that influence breast cancer |
| PMC3446495__F1 | Impaired immune system in patients with systemic lupus erythematosus (SLE) |
| PMC3446651__F2 | Viral proteins inhibit nucleic acid receptors of the intracytosolic innate immune response |
| PMC3446895__F5 | Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells |
| PMC3447932__F10 | Vsx2 Controls Eye Organogenesis and Retinal Progenitor Identity Via Homeodomain and Non-Homeodomain Residues Required for High Affinity DNA Binding |
| PMC3448082__F1 | A simplified model of the feeding regulation hypothesis involving the hypothalamic neuropeptide signaling pathway |
| PMC3448443__F2 | Defining the Molecular Nexus of Cancer, Type 2 Diabetes and Cardiovascular Disease |
| PMC3448682__F7 | Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis |
| PMC3448918__F8 | Proposed mechanism for D10G-mediated suppression of NFKB-regulated gene expression |
| PMC3449280__F1 | An engineered eukaryotic protein glycosylation pathway in Escherichia coli |
| PMC3454471__F5 | Redox regulation of the Nrf2-ARE pathway |
| PMC3455125__F4 | Schematic respresentation of anterograde and retrograde trafficking pathways for KCa2.x (left) and KCa3.1 (right) channels |
| PMC3457170__F4 | JAK/STAT signaling pathway is targeted by RVFV NSs protein at different levels |
| PMC3457296__F8 | LMP2A induces signaling pathways that promote membrane localization of AV-integrin and epithelial migration |
| PMC3457779__F1 | The MAPK cascade activation and potential cross talk signals |
| PMC3457991__F3 | Systematic Analysis of microRNA Targeting Impacted by Small Insertions and Deletions in Human Genome |
| PMC3458056__F5 | Molecular Characteristics and Metastasis Predictor Genes of Triple-Negative Breast Cancer: A Clinical Study of Triple-Negative Breast Carcinomas |
| PMC3458271__F2 | Two proposed models of ephrin-B reverse signaling in palatal EMT based on current evidence |
| PMC3458425__F6 | Docosahexaenoic acid on mouse brain synaptic plasma membrane proteome analyzed by mass spectrometry and 16O/18O labeling |
| PMC3458820__F8 | Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence of Increased 25-Hydroxyvitamin D3 Levels in Male Mice |
| PMC3458933__F7 | Schematic overview of the results from the present study indicating WNT-5A secretion from astrocytes and the WNT-5A-induced signaling pathway towards ERK1/2 regulating distinct aspects of the proinflammatory transformation of microglia |
| PMC3459479__F1 | RAS pathway and its correlation with RASopathies |
| PMC3459479__F2 | RAS Network: cross-links in hypertrophy |
| PMC3459659__F1 | Lipopolysaccharide/TLR4 signalling lipopolysaccharide recognition.Notes: Overview of LPS/TLR4 signalling LPS recognition is facilitated by lipopolysaccharide-binding protein and CD14, and is mediated by TLR4/MD-2 receptor complex |
| PMC3460040__F8 | Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with Sorafenib |
| PMC3460045__F3 | Pathological functions of LOX family oxidases during cancer progression and metastasis |
| PMC3460211__F3 | Formaldehyde-responsive miRNAs predicted to modulate MAM-associated genes in the brains of Mgmt-/- mice |
| PMC3460238__F1b | Central role of AP convertase in complement activation |
| PMC3460412__F1 | Activation of p38 MAPK downstrem of TNFR1 |
| PMC3460904__F7 | Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours |
| PMC3460930__F1 | Lovastatin Induces Multiple Stress Pathways |
| PMC3461086__F3 | Canonical Wnt signaling pathway |
| PMC3461086__F4 | Simplified diagram of signal pathway convergence at downstream nuclear targets |
| PMC3461102__F1 | Cell-Intrinsic Innate Immune Control of West Nile Virus Infection |
| PMC3461213__F1 | Regulatory mechanisms of phosphate homeostasis |
| PMC3461213__F4 | Overall picture of the physiology of FGF-23 and its role in phosphate homeostasis |
| PMC3461241__F3 | Network analysis suggests an immune response and inflammation in ulcerative tissue and non-ulcerative tissue of patients with ulcerative interstitial cystitis (IC) |
| PMC3461519__F2 | B-RAF kinase inhibition by Zelboraf, and molecular mechanisms underlying resistance to Zelboraf treatment |
| PMC3461607__F1 | LPS/TLR-4 signaling pathway.Notes: LPS is delivered to CD14 by LBP, which in turn transfers LPS to TLR-4 |
| PMC3461631__F2 | Signaling cascades mediated by plexin-A and plexin-B, and their crosstalk with oncogenic pathways in gliomas |
| PMC3461903__F2 | New molecular insights into peripheral T cell lymphomas |
| PMC3461905__F2 | Molecular pathogenesis of mantle cell lymphoma |
| PMC3461933__F1 | Looking in the miR-ror: TGFB-mediated activation of NFKB in glioma |
| PMC3461959__F3 | Blastocyst Lineage Segregation and Stem Cells. |
| PMC34619__F2 | Signaling to eukaryotic translation initiation and elongation factors |
| PMC3462113__F1 | Main metabolic reactions in central carbon metabolism.A) Xylose can be assimilated through two pathways: the fungal oxidoreductive pathway consisting of XR and XDH or the bacterial isomerization pathway via an XI |
| PMC3462343__F7 | Model depicting how chronic exposure to SAg could elicit an autoimmune disease |
| PMC3462655__F2 | The signaling pathways involved in T-cell activation |
| PMC3462935__F5 | Schematic diagram depicting the potential interactions between EGF, S100A11, and Ca2+signaling pathway in human endometrial cell |
| PMC3463457__F1 | Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells |
| PMC3463893__F2 | The inductive and effector sites for the mucosal B-cell response in CD |
| PMC3464048__F1 | Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets |
| PMC3464048__F2 | Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets |
| PMC3464089__F2 | Aberrant activation of the MAPK signaling pathway in papillary thyroid tumor cells |
| PMC3464266__F3 | Insights into Pancreatic Cancer Etiology from Pathway Analysis of Genome-Wide Association Study Data |
| PMC3464294__F4 | Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells |
| PMC3464365__F1 | Linking cellular metabolism with the circadian clock transcriptional complex |
| PMC3464683__F3 | Schematic representation of a plant cell with the major components involved in symbiotic signaling and defense signaling |
| PMC3464734__F2 | Pre-treatment expression of TLR, RIG-I and IFN-beta pathway genes compared between the two patient groups |
| PMC3464875__F7 | Signaling involved in MUC4 expression upon Nicotine, IFNG and Retinoic acid stimulation |
| PMC3465072__F1 | Crowdsourcing Network Inference: The DREAM Predictive Signaling Network Challenge |
| PMC3465249__F3 | Changes in hepatic gene expression in the KEGG PPAR signalling pathway in SNEB compared to MNEB cows |
| PMC3465263__F10 | Wortmannin Reduces Insulin Signaling and Death in Seizure-Prone Pcmt1−/− Mice |
| PMC3465331__F6 | In Vivo Tumorigenesis Was Observed after Injection of In Vitro Expanded Neural Crest Stem Cells Isolated from Adult Bone Marrow |
| PMC3465335__F4 | Temperature Dependent Proteomic Analysis of Thermotoga maritima |
| PMC3465517__F5 | Network analysis of proteins found to be significantly altered in abundance in the CSF proteome by ANOVA (p value <0.05) following analysis of individual subject samples |
| PMC3466049__F1 | Complement-targeted therapeutics in periodontitis |
| PMC3466241__F7 | Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway |
| PMC3466334__F1 | Genetically-defined metabolic reprogramming in cancer |
| PMC3466334__F3 | Genetically-defined metabolic reprogramming in cancer |
| PMC3466369__F1 | Emerging Roles for Cholesterol and Lipoproteins in Lung Disease |
| PMC3466406__F2 | The integrated large-scale logical model |
| PMC3466406__F7 | Biological insights obtained by combining logical modeling and experimental data |
| PMC3466441__F1 | Peptide neuromodulation in invertebrate model systems |
| PMC3466494__F1 | GSK3 regulates a variety of pathways involved in neurodevelopment |
| PMC3466514__F1 | S6K1 in ER-positive breast cancer |
| PMC3466807__F1 | BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer |
| PMC3466981__F2 | Ubiquitin ligase complexes SCF and APC/C in ubiquitin-mediated proteolysis of regulatory molecules essential for cell cycle control |
| PMC3466981__F3 | The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis |
| PMC3467044__F9 | Model depicting the molecular underpinnings of lamin B2 origin licensing |
| PMC3467082__F1 | Translation of glutamine codons in yeast |
| PMC3467356__F1 | Regulatory network analysis of the top genes with SNPs with p<0.001 using MetaCore's shortest pathway algorithm (GeneGo Inc.); the nodes that are circled are the genes of interest |
| PMC3467778__F3 | Skewed Th17/Treg cell differentiation in patients with BD, a hypothesis |
| PMC3468386__F1 | The canonical Wnt signaling pathway |
| PMC3468610__F4 | Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing |
| PMC3469060__F6 | Putative mechanisms responsible for UPR activation by CD147 in human HCC cells |
| PMC3469232__F1 | Cholesterol is converted to pregnenolone by cytochrome P450scc inside steroidogenic mitochondria |
| PMC3469471__F2 | Regulation of the human TRAIL gene |
| PMC3469587__F7 | SP-A-regulated signaling pathways in human macrophages |
| PMC3469596__F8 | Neutral lipid and phospholipid biosynthetic pathways |
| PMC3469602__F4 | Serum and Antibodies of Glaucoma Patients Lead to Changes in the Proteome, Especially Cell Regulatory Proteins, in Retinal Cells |
| PMC3469610__F6 | Schematic diagram of proposed molecular mechanism of p27 downregulation in Fen-induced cell growth in fibroids |
| PMC3469622__F1 | Quantitative Phosphoproteomics Reveals SLP-76 Dependent Regulation of PAG and Src Family Kinases in T Cells |
| PMC3469658__F3 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469658__F4 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469658__F5 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469658__F6 | Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes |
| PMC3469673__F1 | Activated CD47 is a proximate regulator of multiple cell survival and cell death pathways |
| PMC3469769__F2 | Multiple roles of COUP-TFII in cancer initiation and progression |
| PMC3470040__F1 | MYCN-dependent apoptosis and the MDM2-p53 pathway |
| PMC3470116__F6 | Simplified schema of putative signaling pathways accountable for the differential responses of A549 (A) and SNB19 (B) cell lines to Hsp90 inhibition and IR |
| PMC3470479__F1 | The Genetics of Alcohol Dependence: Advancing Towards Systems-based Approaches |
| PMC3470584__F2 | Suppressed RNA-Polymerase 1 Pathway Is Associated with Benign Multiple Sclerosis |
| PMC3471161__F1 | VEGF pathway and the site of action of the inhibitors |
| PMC3471227__F1 | Hh pathway activation, inhibition, and mechanisms of drug resistance |
| PMC3471537__F1 | HER2 activation |
| PMC3471675__F6 | Structural Insights into the Common Gamma-Chain Family of Cytokines and Receptors from the Interleukin-7 Pathway |
| PMC3471948__F4 | Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos |
| PMC3471979__F8 | Platelet-Derived Growth Factor CC-Mediated Neuroprotection against HIV Tat Involves TRPC-Mediated Inactivation of GSK 3beta |
| PMC3472459__F5 | Coordinate regulation by NR signaling pathways of genes encoding enzymes in the de novo purine base biosynthesis pathway |
| PMC3472468__F4 | Effects of sleep deprivation on the insulin signaling pathway |
| PMC3472558__F1 | EGFR signaling pathway (reprinted with permission from BioCarta Pathways |
| PMC3472623__F1 | Folate metabolic pathway |
| PMC3472969__F1 | Genotypic-phenotypic model of estrogen metabolism and exposure (yellow box represents genotype component with phenotypic factors outside) |
| PMC3473259__F2 | Main pathway disorders leading to muscle proteolysis, atrophy, hypoxia and anti-oxidant response |
| PMC3473263__F4 | Sample regulation summary diagrams for E |
| PMC3473263__F7 | Subnetwork using the layered layout |
| PMC3474103__F22 | Diagram demonstrating the sites and mechanism of action of novel agents for the management of pancreatic endocrine neoplasm |
| PMC3474186__F3 | Apoptotic signaling through tumor necrosis factor superfamily receptor 6 (Fas) and tumor necrosis factor receptor (TNFR) |
| PMC3474186__F4 | Signaling pathways mediated by rat sarcoma (Ras) and protein kinase B (Akt) |
| PMC3474187__F9 | Methionine sulfoxide and methionine sulfoxide reductase (MSR) redox cycle |
| PMC3474235__F1 | The prostaglandin biosynthetic pathway (adapted from []) 15-deoxyÃŽâ€12-14-PGJ2 is a metabolite derived from arachidonic acid |
| PMC3474235__F2 | Scheme of the various interactions between GSTs and MAPK implicated in stress-signaling pathway (adapted from []) |
| PMC3474261__F1 | MTORC1 signaling and genetic mutations at specific sites in the pathway |
| PMC3474280__F1 | Central position of the locus coeruleus in relation to the acoustic startle reflex and pupillary light reflex pathways |
| PMC3474542__F2 | Nongenomic and genomic estrogen signaling pathways |
| PMC3475164__F1 | Biosynthesis of glycerophospholipids |
| PMC3475172__F1 | Model of canonical eukaryotic translation initiation pathway |
| PMC3475374__F1 | Conceptual schematic of M |
| PMC3475405__F3 | Blood-brain barrier (BBB) transport in homeostasis of brain AB |
| PMC3475613__F2 | Schematic illustrating metabolic pathways prominent in malignant cells |
| PMC3475760__F1 | As a key downstream target of PI3K-mediated signaling pathway in response to extracellular stimuli such as growth factors through receptor tyrosine kinase (RTK), Akt plays an important role in regulation of diverse cellular processes |
| PMC3475803__F7 | A model depicting ATM- and NEMO-mediated NFKB activation upon accumulation of prelamin A isoforms |
| PMC3476325__F9 | Proposed model for how CCL2 signaling through CCR2 signaling regulates survival and motility of breast cancer cells |
| PMC3476735__F5 | Metformin, an anti-diabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway |
| PMC3477504__F3 | Cytokinesis Mechanics and Mechanosensing. |
| PMC3477860__F4 | Schematic diagrams of the role of STAT1 in antimycobacterial, antiviral and antifungal immunity |
| PMC3478095__F2 | Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease |
| PMC3478260__F4 | signaling pathways triggered by L1CAM |
| PMC3478307__F2 | Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K |
| PMC3478427__F2 | Metabolic Actions of Angiotensin II and Insulin: A Microvascular Endothelial Balancing Act |
| PMC3478427__F3 | Metabolic Actions of Angiotensin II and Insulin: A Microvascular Endothelial Balancing Act |
| PMC3478445__F12 | Model of Stat3, Ascl1a, and Lin28a in inducing maximal Müller glial proliferation in the light-damaged zebrafish retina |
| PMC3478592__F1 | Model depicts the development of conventional vs |
| PMC3478884__F1 | Emerging role of nuclear architecture in DNA repair and genome maintenance |
| PMC3478886__F1 | Prognostic Value of Cell-Cycle Regulation Biomarkers in Bladder Cancer |
| PMC3479160__F5 | PPI subnetworks of the extended disease pathways |
| PMC3479191__F5 | Multilevel factors cooperatively perturb pathways |
| PMC3479242__F4 | Optimizing the balance between host and environmental survival skills: lessons learned from Listeria monocytogenes |
| PMC3479314__F1 | SHEDDING NEW LIGHT ON NEURODEGENERATIVE DISEASES THROUGH THE MAMMALIAN TARGET OF RAPAMYCIN |
| PMC3479319__F1 | Wnt signaling cascadesWnt signals can be transduced either through the canonical pathway (colored in pink) or different non-canonical pathways |
| PMC3479343__F7 | Placental PPARG Regulates Spatiotemporally Diverse Genes And A Unique Metabolic Network |
| PMC3480285__F1 | Metabolic Map of Phenolic Metabolism in the Inflorescence Stem of Arabidopsis.The main pathways involved in lignin biosynthesis are framed with a bold black border |
| PMC3480285__F5 | A Systems Biology View of Responses to Lignin Biosynthesis Perturbations in Arabidopsis. |
| PMC3480380__F8 | Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7 |
| PMC3480485__F5 | Forkhead Box M1 (FoxM1) Gene Is a New STAT3 Transcriptional Factor Target and Is Essential for Proliferation, Survival and DNA Repair of K562 Cell Line |
| PMC3480664__F1 | Neurotrophin Regulation of Energy Balance in the Adult CNS and PNS |
| PMC3480720__F1 | Innate immune signals during B |
| PMC3481038__F2 | Scheme demonstrating mechanisms used by natural compounds to drive changes in the epigenome |
| PMC3481051__F3 | The different main molecular pathways that are involved in neuronal stress response |
| PMC3481134__F7 | PRb/E2F signaling pathway mediates three distinct arms of TGFB tumor-suppressive effects |
| PMC3481284__F8 | Schematic diagram of CaMKII regulates Notch1 signaling through proteasomal degradation of SMRT |
| PMC3481450__F6 | Overlapping network between MCF-7 and ZR-75.1 cells |
| PMC3481480__F11 | Pathway Diagram of Oxidative Stress along with PI3k/Akt |
| PMC3481527__F3 | CB1 cannabinoid receptor signalling and regulation of neural stem/progenitor cell proliferation |
| PMC3482007__F1 | CD73-generated adenosine orchestrates the tumor-stroma interplay to promote cancer growth |
| PMC3482366__F1 | Summary of folate metabolic pathway |
| PMC3482395__F2 | Canonical biogenesis pathway and mechanisms of miRNA deregulation |
| PMC3482543__F7 | Toll-Like Receptor 2-Mediated Intestinal Injury and Enteric Tumor Necrosis Factor Receptor I Contribute to Liver Fibrosis in Mice |
| PMC3482685__F2 | Regulatory function of TIR8/SIGIRR in signaling |
| PMC3482945__F3 | Pathway related to prostate cancer |
| PMC3483025__F1 | Metabolic pathway of tetrapyrrole biosynthesis in plants |
| PMC3483307__F5 | Novel Genes and Pathways Modulated by Syndecan-1: Implications for the Proliferation and Cell-Cycle Regulation of Malignant Mesothelioma Cells |
| PMC3484277__F1 | Downstream signaling of the IGF-1R |
| PMC3484277__F2 | Insulin like growth factor (IGF) and insulin receptor (IR) signaling system |
| PMC3484412__F2 | Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway [] |
| PMC3484421__F2 | The PI3K/Akt/mTOR pathway: Ligands binds to the receptor tyrosine kinases like EGFR, IGF1R, Her2, and Ras leads to conformational changes and activates PI3K |
| PMC3484431__F9 | Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma |
| PMC3484588__F4 | Cellular affects of TNFA.Tumour Necrosis Factor alpha (TNFA) is produced by macrophages, lymphocytes, fibroblasts and keratinocyte |
| PMC3484676__F3 | Rbf1 occupies multiple nodes in conserved signaling pathways |
| PMC3485057__F4 | Increased Biomass Yield of Lactococcus lactis by Reduced Overconsumption of Amino Acids and Increased Catalytic Activities of Enzymes |
| PMC3485747__F1 | Glutamine:fructose-6-phosphate amidotransferase 1 (GFPT1)-mediated MTOR signaling pathway affected by glucose and fructose in porcine trophectoderm cells |
| PMC3486458__F7 | AMPK/ERK/TSC2/mTOR signaling in PCV2-induced autophagy in PK-15 cells |
| PMC3486512__F3 | Network analysis of the host factors found to be associated with the extremities of the murine norovirus genome |
| PMC3488095__F8 | A model for SAHA mediated effects on A1AT folding and trafficking |
| PMC3488108__F1 | Immune-Neuroendocrine Integration at the Adrenal Gland: Cytokine Control of the Adrenomedullary Transcriptome |
| PMC3488210__F3 | Sub-network found among the genes in a differential expression experiment that compares FA patients to controls |
| PMC3488210__F5 | Significant sub-networks (see also ) found among the lists of most essential genes, ranked by the RIGER parameter, obtained for both cell lines: (A) Jurkat and (B) K562 |
| PMC3488313__F4 | Proposed mechanism of associated vWF activating GPIIb/IIIA |
| PMC3488588__F1 | Roles and Regulation of Secretory and Lysosomal Acid Sphingomyelinase |
| PMC3488630__F2 | Proposed model of HER2/3 signaling in epithelial cells |
| PMC3488811__F1 | Simplified diagram of choline-related one-carbon metabolism |
| PMC3489622__F2 | Signaling networks induced in the spleen at 1 day post infection in wild-type mice (A) and STAT1 KO mice (B) |
| PMC3489747__F2 | TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis |
| PMC3489757__F1 | New insights on the role of CD8+CD57+ T-cells in cancer |
| PMC3489783__F3 | Representative KEGG pathway change of Endocytosis |
| PMC3489928__F4 | Proposed Reaction Pathway |
| PMC3490020__F1 | The main MicroRNA biosynthetic pathway |
| PMC3490280__F2 | Recipient T-lymphocytes govern Mesenchymal stem cell (MSC)-based bone regeneration via IFNG and TNFA |
| PMC3490581__F4 | Illustration of fluxes in central carbon metabolism for metabolic phases II and III along the protein/ tradeoff |
| PMC3490606__F1 | Reactions involved in the flux of fatty acids into |
| PMC3491070__F3a | Cancer Cell Metabolism: One Hallmark, Many Faces |
| PMC3491089__F4 | Schematic representation which shows possible mechanisms of action by D- and Gamma-tocopherol in multiple signaling pathways involved in mammary carcinogenesis |
| PMC3491533__F8 | Diagrammatic presentation shows how Notch and TGFB signaling pathway involved at each pathogenic stage of HBV infection |
| PMC3491752__F3 | CYTOPROTECTIVE PROTEIN C PATHWAYS AND IMPLICATIONS FOR STROKE AND NEUROLOGICAL DISORDERS |
| PMC3491806__F2 | Inflammatory Bowel Disease |
| PMC3491811__F3 | Calcium regulation of keratinocyte differentiation |
| PMC3491835__F7 | 5-HT6 receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia |
| PMC3491906__F1 | Distinct signaling pathways of synaptic and extrasynaptic NMDAR in neuron fate |
| PMC3491909__F1 | Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR |
| PMC3492042__F3 | MicroRNA targetome suggests aberrant upregulation of cell cycle regulators in AD brains |
| PMC3492042__F5 | MicroRNA targetome suggests aberrant upregulation of T cell receptor signaling pathway molecules in ATL cells |
| PMC3492042__F8 | MicroRNA targetome suggests aberrant upregulation of cell cycle regulators in AD brains |
| PMC3492204__F5 | A simplified scheme to illustrate the dual roles played by KIF7 in Indian Hedgehog (IHh) signaling and chondrocytes development |
| PMC3492208__F3 | Principal IFN-Alpha-modulated canonical pathway in MT-4 cells |
| PMC3492658__F1 | NOD1 and NOD2 signaling pathways and interaction partners |
| PMC3492703__F1 | Biosynthesis and posttranscriptional processing of miRNA |
| PMC3492801__F1 | Core PCP module in Drosophila |
| PMC3492913__F1 | Diagrammatic representation of BMP signaling pathway |
| PMC3492937__F5 | Stem cell pathways analysis for label-retaining cancer cell (LRCC) |
| PMC3492958__F1 | Distinct roles for AlphaB hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling |
| PMC3493339__F1 | ERBB Pathway |
| PMC3493339__F4 | STRING Network |
| PMC3493385__F2 | RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways |
| PMC3493453__F7 | Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage |
| PMC3493591__F5 | Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28 |
| PMC3493640__F1 | Multi-omic map of the lipid-producing yeast Rhodosporidium toruloides |
| PMC3493824__F1 | Cellular Targeting in Autoimmunity |
| PMC3493824__F2 | Cellular Targeting in Autoimmunity |
| PMC3493873__F1 | TP53 mutation status-specific network of potential candidate driver genes shown based on their known and predicted functional interactions |
| PMC3493902__F8 | The diagram illustrates the possible mechanism of tumor cells-secreted CCN1 in regulation of pancreatic carcinogenesis through the regulation of SHh signaling |
| PMC3493930__F8 | Mechanisms by which AP-1 transcription factor regulates LY6K expression, which activates the ERK signaling pathway to mediate cell invasive motility and metastasis in human breast cancer cells |
| PMC3494084__F4 | Baculovirus infection impact on host cell metabolism |
| PMC3494149__F6 | VANTED integrated pathway map of quantitative regulation of metabolites and enzymes of primary metabolism under nitrogen limitation in Chlamydomonas reinhardtii |
| PMC3494151__F4 | Impact of SIRT1 knockout on selected cellular pathways and protein complexes |
| PMC3494185__F7 | Hypothetical schematic of the roles of KPNA2 and E2F1 in NSCLC |
| PMC3494243__F2 | Pathways for C18 PUFA conversion to C20-22 PUFA synthesis |
| PMC3494542__F3 | TGFB non-canonical signaling pathway |
| PMC3494587__F12 | Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes |
| PMC3494597__F1 | Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells |
| PMC3494605__F1 | A role for vimentin in Crohn disease |
| PMC3494627__F3 | Cancer-suppressive inflammation |
| PMC3494767__F5 | Synergistic cancer cell death in response to stress when TSC2, but not Pten is inactivated in the context of a deregulated Rb pathway |
| PMC3495118__F1 | Transcriptional regulation of the cytoprotective phase 2 genes under control of the transcriptional factor nuclear factor-E2 p45-related factor 2 (Nrf2) |
| PMC3495133__F1 | Schematic of the desaturation and elongation biosynthetic pathway of essential dietary fatty acids to longer chain fats |
| PMC3495805__F1 | Functional roles of pluripotency transcription factors in mesenchymal stem cells |
| PMC3495983__F6 | Model illustrating CD40-induced signals that mediate the expression of VEGF in endothelial cells |
| PMC3496019__F1 | Cancer Stem Cells |
| PMC3496019__F2 | Regulation of CSCs by inflammatory cytokine networks |
| PMC3496044__F7 | Sialic acid biosynthetic and degradative pathways |
| PMC3496878__F1 | Signal transduction in solid cancer cells including hepatocellular carcinoma |
| PMC3496878__F4 | Phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signaling pathway in cell proliferation in solid cancer |
| PMC3497051__F4 | Autophagy process |
| PMC3497272__F2 | ErbB signaling and inhibition in tumour cell |
| PMC3497295__F1 | Selected signaling pathways in renal cell carcinoma (RCC) |
| PMC3497822__F1 | The signaling pathway by which FSH promotes AKT activation in GCs |
| PMC3497822__F7 | The signaling pathway by which FSH promotes AKT activation in GCs |
| PMC3498232__F9 | Expression Profile in Rice Panicle: Insights into Heat Response Mechanism at Reproductive Stage |
| PMC3498346__F1 | Impaired Skeletal Muscle Regeneration in the Absence of Fibrosis during Hibernation in 13-Lined Ground Squirrels |
| PMC3498483__F2 | The crosstalk between classical and non-classical mechanisms in female reproductive behavior |
| PMC3498840__F1 | TLR signaling overview: the TLR family can be subdivided into two categories |
| PMC3499024__F2 | Bone anabolism regulated by statins |
| PMC3499061__F2 | Schematic illustrations of the two significant pathways in the genome-wide gene self-reported asbestos exposure interaction analysis |
| PMC3499080__F2 | Alterations in the NRF2 canonical pathway in livers of mice treated with TMHF |
| PMC3499189__F2 | Synopsis of major pathways activating mTORC1 |
| PMC3499189__F3 | Aberrations of PI3K-Akt-mTORC1 signaling pathway in prostate cancer |
| PMC3499364__F7 | Genome, Functional Gene Annotation, and Nuclear Transformation of the Heterokont Oleaginous Alga Nannochloropsis oceanica CCMP1779 |
| PMC3499368__F1 | Evolution of Minimal Specificity and Promiscuity in Steroid Hormone Receptors |
| PMC3499531__F6 | Transcriptome Sequencing and Annotation for the Jamaican Fruit Bat (Artibeus jamaicensis) |
| PMC3499662__F1 | Cell-signaling pathways from the UPR to autophagy and ER stress-induced apoptosis |
| PMC3499814__F2 | RIG-I signaling pathway and inhibition by influenza A viruses (Figure adapted from []) |
| PMC3499814__F3 | Type I IFN signaling pathway and inhibition by influenza A viruses (Figure adapted from []) |
| PMC3499881__F1 | Regulation of the polyamines putrescine, spermidine and spermine by biosynthetic enzymes (shown in green) and catabolic enzymes (shown in red) |
| PMC3499976__F1 | Wnt transduction pathways and their functions during synapse development, function and plasticity |
| PMC3499997__F2 | Main therapeutic targets along the BCR signaling pathway in CLL cells |
| PMC3500394__F1 | FoxM1 and Wntβ-catenin Signaling in Glioma Stem Cells. |
| PMC3500439__F1 | Molecular Pathways: The Metabolic Regulator Estrogen-Related Receptor Alpha as a Therapeutic Target in Cancer |
| PMC3500654__F7 | The inter-relationship between hepcidinand HJVexpression during the inflammatory response, and the effect on iron flux |
| PMC3500781__F1 | Two different pathways could bypass DNA damage causing stalled replication forks |
| PMC3500850__F4 | Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response |
| PMC3500853__F3 | EphrinB reverse signaling |
| PMC3500863__F3 | Pathways regulating NEKs in cell cycle control |
| PMC3501016__F1 | Finding a New Regulator of the Blood Coagulation Cascade♦ |
| PMC3501082__F7 | A model to depict Tollip cooperating with Smad7 to mediate degradation of the TGFB receptor complex |
| PMC3501207__F1 | Cholesterol Accumulation Regulates the Expression of Macrophage Proteins Implicated In Proteolysis and Complement Activation. |
| PMC3501223__F1 | Role of Esrrb in ESC self-renewal and reprogramming |
| PMC3501616__F4 | Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome wide association on chromosome 1p22 |
| PMC3502106__F5 | Figure 8: Feed-forward signaling in which FGF-9 controls Wnt-2a expression and mesenchymal Wnt/Beta-catenin signaling, and in which mesenchymal Wnt/Beta-catenin signaling is requisite for mesenchymal FGFR expression and mesenchymal responsiveness to FGF-9 |
| PMC3502514__F1 | Activation of stress signalling pathways in the liver of sows during lactation |
| PMC3502626__F7 | A theoretical model of synergistic interactions between resveratrol and HDAC inhibitors is presented |
| PMC3502657__F1 | Signaling pathways for longevity |
| PMC3502657__F2 | Signaling pathways for longevity |
| PMC3502714__F2 | Fibroblast growth factor 23: State of the field and future directions |
| PMC3502714__F3 | Fibroblast growth factor 23: State of the field and future directions |
| PMC3502766__F5 | Proposed metabolic pathway for the degradation of VFA and TCE inferred from the metaproteomic data |
| PMC3502787__F1 | General features of the HER family |
| PMC3502876__F1 | Reactive oxygen species-mediated autophagy regulation |
| PMC3502886__F1 | PI3K/Akt/mTOR pathway regulates central carbon metabolism |
| PMC3503525__F1 | WNTS AND TGFB IN SYNAPTOGENESIS: OLD FRIENDS SIGNALLING AT NEW PLACES |
| PMC3503557__F5 | Network and pathway structure for biologically informative priors in the cancer drug response data study |
| PMC3504253__F1 | Inactivated Wnt pathway |
| PMC3504253__F2 | Activated Wnt pathway |
| PMC3504364__F2 | Methotrexate (MTX) mechanisms of action in the folate metabolic pathway |
| PMC3504424__F3 | Canonical Wnt-Beta-catenin pathway |
| PMC3504424__F4 | Tyrosine kinase receptors pathway |
| PMC3504424__F5 | Transforming growth factorB (TGFB) pathway |
| PMC3504431__F1 | MTOR pathway |
| PMC3504641__F1 | Schema of the cholesterol pathway |
| PMC3504715__F8 | Cytokine-induced CITED2/MYC/E2F3/p21CIP1signaling in lung cancer |
| PMC3504728__F7 | Speculative model of macrophage alternative activation regulation by estrogen |
| PMC3505266__F3 | Heterogeneity in the differentiation and function of memory B cells |
| PMC3506510__F2 | Signaling pathways impinging on autophagy |
| PMC3506908__F4 | Pathway analysis derived by comparison of the relative abundance of metabolites from sera derived from patients with locoregional CRC and liver-only metastases, as determined by GC-MS |
| PMC3507178__F3 | Flow chart depicting the metabolic pathway of fatty acids in the liver of GH transgenic Amago based on 3'-tag digital gene expression profiling and comparison of serum triacylglycerol and glucose, and 3-hydroxybutyric acid |
| PMC3507180__F2 | Hypothetic regulation of gene expression by HNF-4A by spherical cell shape in FLC-4 cells |
| PMC3507272__F1 | Schematic diagram showing the RAS-MAPK signal transduction pathway |
| PMC3507315__F2 | T cell receptor signaling pathway extracted from BioCarta database [] |
| PMC3507315__F3 | Fc epsilon receptor I signaling in mast cell pathway extracted from BioCarta database [] |
| PMC3507315__F9 | mTOR signaling pathway extracted from KEGG database [] |
| PMC3507431__F2 | Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy |
| PMC3507479__F1 | An expanded role of the tumor suppressor TSC1 in T cell tolerance |
| PMC3507808__F1 | Metabolites and their metabolic pathway networks measured by the Arg/Thiol Redox Metabolomics Assay |
| PMC3508164__F12 | Proposed model of Cripto-1 modulation of the Wnt/Beta-catenin signaling pathway |
| PMC3508169__F2 | Known relationships between the candidate genes |
| PMC3508196__F1 | TARGETING ONCOGENIC BRAF IN HUMAN CANCER |
| PMC3508273__F4 | The role of tumor-associated macrophages (TAMs) during tumor angiogenesis |
| PMC3508562__F1 | Diagram representing the possible endogenous and exogenous TLR activation pathways and the accompanying response.Abbreviation: TLR, toll-like receptor |
| PMC3508562__F2 | Genomics in cardiovascular diseases: analysis of the importance of the toll-like receptor signaling pathway. |
| PMC3508619__F1 | MYC proteins and the p53/MDM2/p14ARFpathway |
| PMC3508723__F8 | Model of Tat/Beta-catenin interaction in astrocytes |
| PMC3509372__F1 | Treg regulatory pathways |
| PMC3509664__F3 | PKR and the Insulin signaling pathway |
| PMC3509664__F7 | HCV and induction of the innate immune response |
| PMC3509664__F8 | PKR, ISG15 as modulators of IFN induction during HCV infection |
| PMC3509680__F3 | Functional roles of the arenavirus Z protein in the viral life cycle |
| PMC3509687__F1 | Impact of the cellular restriction factor APOBEC3 (A3) on human immunodeficiency virus-1 (HIV-1) replication |
| PMC3509712__F1 | Signal transduction pathways used by superantigens and mediators |
| PMC3509892__F1 | Transcriptional Changes Associated with Lack of Lipid Synthesis in Parasitoids |
| PMC3509894__F3 | Vitamin B12 Synthesis and Salvage Pathways Were Acquired by Horizontal Gene Transfer to the Thermotogales |
| PMC3510027__F2 | Genome-Scale RNA-Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease |
| PMC3510027__F3 | Genome-Scale RNA-Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease |
| PMC3510123__F7 | Eliminating the SLAC1 anion channel affects K+ channel activity, K+ uptake, and the rate of stomatal opening through its impact on and as predicted by the OnGuard model (; ) |
| PMC3510514__F6 | Model for the role of Spartan in DNA damage tolerance |
| PMC3510826__F8 | Important roles of SFKs in G protein-coupled receptor-induced platelet activation |
| PMC3511325__F9 | Protective Role of STAT3 in NMDA and Glutamate-Induced Neuronal Death: Negative Regulatory Effect of SOCS3 |
| PMC3511450__F5 | Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways. |
| PMC3512067__F5 | Model illustrating how nicotine plus a HFD could exacerbate HFD-induced hepatic steatosis in obese mice |
| PMC3512134__F6 | Overall organization of mitotic exit control |
| PMC3512188__F3 | Roles of miRNAs in DNA damage response |
| PMC3512410__F2 | Scheme depicting the different outcomes caused by the presence of progerin and prelamin in cells |
| PMC3512574__F3 | TGFB in Cancer |
| PMC3512574__F5 | TGFB in Cancer |
| PMC3513217__F2 | Schematic illustration of irinotecan disposition pathway |
| PMC3513217__F3 | Metabolism pathway of tamoxifen and its interaction with estrogen receptors.Copyright © 2009 |
| PMC3513219__F2 | XRCC1 is instrumental in base excision repair (BER) of small oxidative lesions and a related mechanism for the repair of single-strand breaks (SSB-R), both caused by ionizing radiation |
| PMC3513309__F3 | Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, InterferonA and Dendritic Cell Vaccine |
| PMC3513309__F4 | Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, InterferonA and Dendritic Cell Vaccine. |
| PMC3513366__F1 | Progastrin Peptides Increase the Risk of Developing Colonic Tumors: Impact on Colonic Stem Cells |
| PMC3513650__F1 | BRCA and RAD52 pathways of DNA double-strand break (DSB) repair |
| PMC3513735__F3 | Most enriched molecular networks showing interactions between the significant genes (according to SAM)–(a) FOSB, ERK, MAPK3, CYR61, and the RAS-genes; (b) DUSP1, ERK1/2, P38MAPK, DUSP9, and RASD1; (c) CYR61 and NFRKB |
| PMC3513881__F3 | Proposed three pathways for the mechanism of nicotinic acetylcholine receptor (nAChR)-mediated survival signal transduction |
| PMC3513983__F3 | Major signaling pathways regulating RSV-induced NFKB and IRF activation in airway epithelial cells |
| PMC3514012__F5 | IPA generates IL-17C interactome |
| PMC3514292__F1 | Schematic representation depicting A; the protein synthesis pathway in skeletal muscle involving the mammalian target of rapamycin complex 1 (mTORC1) |
| PMC3514351__F1 | Ingenuity pathways analysis summary |
| PMC3514454__F7 | Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo |
| PMC3514612__F7 | Synthesis of nitric oxide and transduction cascades |
| PMC3514620__F2 | DNA repair pathways and implicated proteins |
| PMC3514635__F4 | Intracellular trafficking proteins involved in CMT neuropathy |
| PMC3514733__F1 | Chemotactic signaling pathway in sperm |
| PMC3514827__F1 | Using components of the Vitamin D pathway to prevent/treat colon cancer |
| PMC3514880__F3 | Genome sequences of wild and domestic bactrian camels |
| PMC3514894__F1 | Interplay between Smoking-induced Genotoxicity and Altered Signaling in Pancreatic Carcinogenesis |
| PMC3514907__F3 | GeneGo "Cell Adhesion_ECM remodeling" pathway map |
| PMC3515033__F2 | Classification of Toll-like receptors (TLRs) |
| PMC3515033__F3 | Classification of nucleotide-binding oligomerization domain proteins (Nods) |
| PMC3515033__F4 | Neural and humoral activation of the brain by the periphery |
| PMC3515033__F5 | Cytokine intracellular signaling pathways |
| PMC3515332__F1 | Class I PI3K/Akt/mTOR axis pathway |
| PMC3515549__F7 | Screening the Budding Yeast Genome Reveals Unique Factors Affecting K2 Toxin Susceptibility |
| PMC3515668__F1 | Schematic representation of the potential disruption of the hepatic GHR-JAK2-STAT5b signal transduction pathway by TCDD |
| PMC3515677__F1 | Summary of the mechanisms of DC-mediated HIV-1 transmission to CD4+ T cells |
| PMC3515920__F1 | Retinoid refractoriness due to phosphorylation of retinoid X receptor alpha (RXR A), and its restoration by acyclic retinoid (ACR) in liver carcinogenesis |
| PMC3516044__F3 | Changes in the Plasmodium falciparum redox flux network after MB drug action.Notes: Results incorporating the transcription data and experimental mRNA expression data nine hours after incubation with methylene blue are shown |
| PMC3516599__F1 | Proposed Multicompartmental Degradative Pathway of L-lysineL-Lysine degradation is initiated by either peroxisomal Alpha-deamination (pipecolate pathway) or mitochondrial E-deamination (saccharopine pathway) |
| PMC3516764__F9 | Model for the involvement of the RA in neuronal differentiation |
| PMC3516782__F5 | Metabolic pathway of mannan in R |
| PMC3516830__F2 | Interaction loop between the EGFR signaling pathway and miR-221/222 expression in the modulation of cellular processes |
| PMC3517080__F5 | Putative Altered Signaling Events occurring upon treatment of GSI |
| PMC3517092__F1 | Schematic depiction of the role of the retromer complex in mediating endosomal protein sorting |
| PMC3517178__F2 | Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression |
| PMC3517193__F1 | Graphic illustration of the perturbation of the insulin signal transduction pathways by cellular stressors |
| PMC3517549__F1 | The Evolution and Origin of Animal Toll-Like Receptor Signaling Pathway Revealed by Network-Level Molecular Evolutionary Analyses. |
| PMC3517549__F5 | Evolution and Origin of Animal Toll-Like Receptor Signaling Pathway Revealed by Network-Level Molecular Evolutionary Analyses |
| PMC3517581__F7 | Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal SH-SY5Y Cells. |
| PMC3517905__F1 | Summary of the signaling pathways of PKMζ-mediated late-LTP |
| PMC3518132__F8 | Alkylphospholipid (ODPC)-induced raft-based inhibition of cell signaling |
| PMC3518257__F7 | 14-3-3 signaling canonical pathway from IPA |
| PMC3518431__F1 | Autophagy modulation as a potential therapeutic target for diverse diseases |
| PMC3518431__F2 | Autophagy modulation as a potential therapeutic target for diverse diseases |
| PMC3518467__F1 | Fast, Potent Pharmacological Expansion of Endogenous Hes3+/Sox2+ Cells in the Adult Mouse and Rat Hippocampus |
| PMC3518543__F4 | NFKB activation pathway is regulated by S-nitrosylation |
| PMC3518557__F1 | Targets and structure of compstatin |
| PMC3518570__F2 | Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease |
| PMC3518582__F1 | Wnt Signal Transduction Pathways |
| PMC3518582__F3 | Wnt7a signals bidirectionally through divergent pathways to influence both presynaptic and postsynaptic assembly and to promote excitatory synapse formation and function |
| PMC3518608__F1 | Potential mechanisms of protein nitrosothiol formation and degradation |
| PMC3518628__F1 | Interplay between Wnt/Beta-catenin signaling and HIV: Virologic and biologic consequences in the CNS |
| PMC3518628__F3 | Interplay between Wnt/Beta-catenin signaling and HIV: Virologic and biologic consequences in the CNS |
| PMC3518872__F3 | Top three networks of significantly associated molecules in TGFB1+LPS+IFNGamma-treated astrocytes |
| PMC3518872__F4 | Three IPA Canonical Signaling Pathways: CD40, IL-1, and Chemokine Signaling in TGFB1+LPS+IFNGamma-treated astrocytes |
| PMC3518872__F6 | GPCR Canonical Signaling Pathways |
| PMC3519537__F1 | Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing |
| PMC3519537__F5 | Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing |
| PMC3519901__F7 | Quantification of the Host Response Proteome after Mammalian Reovirus T1L Infection |
| PMC3519947__F1 | Simplified diagram illustrating the mTOR signaling pathway |
| PMC3519956__F6 | Schematic model depicting how HMW isoforms regulate bone formation |
| PMC3520003__F1 | Simplified summary of the role of ATGL in macrophages.FFAs which are taken up by macrophages are incorporated into TGs (and cholesteryl esters) |
| PMC3520043__F2 | Assumed role of mitochondria, Ca2+, and ROS in neuronal excitotoxicity and epileptogenesis |
| PMC3520045__F4 | Summary diagram of Nrf2 and HIF1 stimulation in presence of oxidative stress |
| PMC3520048__F2 | Summary of the role of the mammalian target of rapamycin (mTOR) signaling pathway in the development of tuberous sclerosis complex (TSC) and inhibition by mTOR inhibitors |
| PMC3520539__F1 | Generalized overview of the regulation of apoptosis by sphingolipids |
| PMC3520542__F13 | Molecular mechanism for Elovl5 control of mTORC2, FoxO1-S256 phosphorylation, and hepatic GNG |
| PMC3520610__F1 | Targeting the TGFB signalling pathway in disease |
| PMC3520610__F2 | Targeting the TGFB signalling pathway in disease |
| PMC3520610__F5 | Targeting the TGFB signalling pathway in disease |
| PMC3520613__F5 | Macrophage VLDL Receptor Promotes PAFAH Secretion in Mother's Milk and Suppresses Systemic Inflammation in Nursing Neonates |
| PMC3520616__F1 | Upstream events in BCR signaling |
| PMC3520885__F2 | R(h)oads to microvesicles |
| PMC3520888__F1 | Escorting Ras |
| PMC3521040__F2 | Molecular mechanisms of activation, amplification, regulation, and evasion of the AP C3 convertase |
| PMC3521191__F1 | Biological pathways targeted for therapy in renal cell carcinoma based on a knowledge of the underlying genetic changes and downstream biological consequences |
| PMC3521201__F1 | Central carbon metabolism pathways in E |
| PMC3521387__F7 | ILOCi detected genes from BD and their maps in 'neuroactive ligand-receptor interaction' pathway |
| PMC3521387__F8 | ILOCi detected genes from CAD and their maps in 'cytokine-cytokine receptor interaction' pathway |
| PMC3521387__F9 | ILOCi detected genes from T1D and their maps in 'type I diabetes mellitus' pathway |
| PMC3521791__F6 | Part of the top canonical pathway affected by in vivo LPS administration into the human lung |
| PMC3522471__F1 | Metabolic Pathway for the Formation of CHB (1) and CBO (2) from BD, and the Subsequent Reactions of CBO with GSH to Form Three CBO-GSH Conjugates (3, 4, and 5) |
| PMC3522553__F1 | Components of the Hedgehog (Hh) Signaling Pathway and molecular sites targeted by Hh pathway inhibitors |
| PMC3522801__F1 | DNA Damage Signaling Assessed in Individual Cells in Relation to the Cell Cycle Phase and Induction of Apoptosis |
| PMC3522801__F2 | DNA Damage Signaling Assessed in Individual Cells in Relation to the Cell Cycle Phase and Induction of Apoptosis |
| PMC3523093__F1 | Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches |
| PMC3523565__F1 | Simplified scheme of the mitogen-activated protein kinase (MAPK) (RAS-RAF-MEK-ERK) signaling pathway.Notes:BRAF and NRAS are the most commonly mutated oncogenes in melanoma |
| PMC3523725__F7 | PPARG COUNTERACTS LRP1-INDUCED VASCULAR CALCIFICATION BY INHIBITING A WNT5A SIGNALING PATHWAY |
| PMC3523810__F7 | Possible inflammatory signaling pathway that results from the functional associations of the identified inflammation-related proteins (marked with an underline), which is regulated by acupuncture in asthma |
| PMC3523822__F1 | Biosynthetic pathway of diphthamide in eukaryotes |
| PMC3524013__F3 | Full network comparison of the original canonical pathway and the inferred cell-type-specific pathway |
| PMC3524085__F7 | Ingenuity pathway analysis of the 10-edge pattern subgraph showing cancer-associated interactions among its nodes |
| PMC3524152__F2 | Bacterial effector targets the TRAF6-NFKB pathway to modulate the acute inflammatory response to bacterial invasion of epithelial cells |
| PMC3524155__F1 | Sensing the enemy |
| PMC3524194__F1 | Upstream regulators of the Hippo pathway |
| PMC3524227__F1 | Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells |
| PMC3524319__F6 | Construction of the regulatory networks associated with the selected genes using IPA® database |
| PMC3524627__F8 | Model depicting the regulation of DNA damage-induced germ cell apoptosis by C |
| PMC3524689__F2 | Proposed model of OGP(10-14) differentiation signalling |
| PMC3524696__F1 | Schematic diagram represents the ischemic preconditioning pathway in cardiomyocytes |
| PMC3525024__F7 | Schematic representation of canonical and noncanonical Hh signaling activation in MM |
| PMC3525110__F3 | Proposed model for EA signaling |
| PMC3525180__F3 | Some perifosine-specific genes are connected by common pathways leading to MAPK signalling pathway and apoptosis |
| PMC3525581__F7 | Toxicogenomic Analysis Suggests Chemical-Induced Sexual Dimorphism in the Expression of Metabolic Genes in Zebrafish Liver |
| PMC3525723__F4 | Insulin signaling transduction |
| PMC3526371__F1 | NFKB activation in pathogenesis and therapy of cancer |
| PMC3526508__F2 | Becoming a follicular or a MZ B-cell? |
| PMC3526895__F9 | Schematic model of the signaling pathway activated by redox/metabolic imbalance and its possible positive impact on human lifespan |
| PMC3527145__F1 | The left-right asymmetry pathway |
| PMC3527239__F2 | Metabolic pathways of TAG synthesis and degradation and their subcellular localization (adapted from and ) |
| PMC3527239__F5 | Compartmentalization of the Beta-oxidation pathway and the glyoxylate cycle |
| PMC3527322__F1 | Amniotic fluid stem cells to study mTOR signaling in differentiation |
| PMC3527539__F7 | Up-regulated miR155 Reverses the Epithelial-mesenchymal Transition Induced by EGF and Increases Chemo-sensitivity to Cisplatin in Human Caski Cervical Cancer Cells |
| PMC3527608__F6 | Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms |
| PMC3527701__F2 | Mammalian N-end rule pathway.,,, N-terminal residues are indicated by single-letter abbreviations for amino acids |
| PMC3527831__F1 | Scaffolds KSR and Ste5 in MAPK signaling |
| PMC3527886__F2 | Network of biglycan signaling in osteoblast differentiation and stabilizing role of biglycan in skeletal muscle |
| PMC3527976__F2 | Two rapamycin-sensitive myogenic mTOR signaling pathways |
| PMC3528279__F2 | Toll-Like Receptors (TLR) signaling pathway involved in hMPV-induced gene expression in primary immune cells |
| PMC3528279__F3 | RIG-I/MAVS signaling pathway regulating hMPV-induced NFKB and IRF activation in airway epithelial cells |
| PMC3528293__F1 | Generalized overview of the extrinsic and intrinsic apoptosis pathways |
| PMC3528378__F3 | Mechanism of muscle protein synthesis inhibition by GCs |
| PMC3528566__F2 | Carbohydrate metabolism and ATP synthesis |
| PMC3528620__F4 | Chemokine Signaling Pathway from the KEGG database (ID: mmu04062) overlaid with log2 fold change values for genes differentially expressed between DBA/2 and C57BL/6 at day 14 |
| PMC3528779__F6 | Global Effect of Inauhzin on Human p53-Responsive Transcriptome |
| PMC3529366__F6 | BMP2-WNT4-FOXO1 pathway in HESC differentiation |
| PMC3529568__F1 | TGFB latency, activation and signal transduction |
| PMC3529674__F5 | MyD88-independent TLR signaling |
| PMC3529762__F11 | Illustration of GnRH signaling pathways necessary for FSHB induction |
| PMC3529804__F3 | Novel Directions for Diabetes Mellitus Drug Discovery |
| PMC3529810__F7 | Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response |
| PMC3530456__F5 | Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis |
| PMC3530555__F5 | Combined Inhibition of IGF-1R/IR and Src Family Kinases Enhances Antitumor Effects in Prostate Cancer by Decreasing Activated Survival Pathways |
| PMC3530773__F3 | Vasopressin signaling network |
| PMC3531074__F3 | Network exploration options |
| PMC3531240__F11 | IFNA and LPS up-regulate APOBEC3 (A3) mRNA through different signaling pathways |
| PMC3531289__F1 | Chapter 3: Small Molecules and Disease |
| PMC3531707__F3 | PERK signaling under virus attack |
| PMC3531712__F1 | p62-interacting partners and functions |
| PMC3531730__F6 | Proposed model for the signaling pathway mediating NFKB activation induced by C-type lectin receptors |
| PMC3531794__F1 | Impact of IL-27 on lymphocyte signaling pathways |
| PMC3531868__F1 | Receptors for IL4 and IL13 are comprised of four different subunits, IL4RA (green), gamma chain (Gc; purple), IL13RA1 (red), and IL13RA2 (yellow) |
| PMC3532050__F1 | NFKB inhibition by A20 in the TNFR1 signaling pathway |
| PMC3532163__F4 | Characterization of the Phosphoproteome in SLE Patients |
| PMC3532179__F1 | Mathematical model of the apoptotic pathways induced by cisplatin |
| PMC3532379__F3 | Functional "DASE" networks |
| PMC3532456__F2 | Transforming growth factor (TGF)B signaling pathway |
| PMC3532456__F3 | Interleukin (IL)-13 and IL-4 signaling pathway |
| PMC3532605__F7 | NFKB signalling pathway |
| PMC3532876__F2 | Vicious spirals of repeating self-accelerating oxidative stress and dysregulated redox and information signaling as possible causes of type 2 diabetes |
| PMC3533285__F11 | SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation |
| PMC3533361__F1 | GSK3 signaling in neural development |
| PMC3533463__F1 | Biosynthesis pathways of phospholipid components in archaea |
| PMC3533466__F1 | Genes whose mRNA expression is suppressed by nicotine in RAW264.7 cells under poly(I:C) stimulation compared with those under poly(I:C) stimulation only are mapped to three gene networks, as predicted by ingenuity pathway analysis (IPA) |
| PMC3533466__F5 | Nicotine's effect on multiple signal transducers in the downstream pathway of calcium |
| PMC3533556__F7 | IL-13-induced airway mucus production is attenuated by MAPK13 inhibition |
| PMC3533650__F10 | Regulation of the FOXO3a survival, and glycolysis pathways under hypoxia in Spalax |
| PMC3534167__F2 | Hodgkin lymphoma |
| PMC3534236__F3 | Autophagy and selective deployment of Atg proteins in antiviral defense |
| PMC3534598__F1 | Cartoon depicting the role of sialidases during the multistep process of myogenesis |
| PMC3534691__F8 | Neuregulin Facilitates Nerve Regeneration by Speeding Schwann Cell Migration via ErbB2/3-Dependent FAK Pathway |
| PMC3534787__F9 | Vorinostat, an HDAC Inhibitor Attenuates Epidermoid Squamous Cell Carcinoma Growth by Dampening mTOR Signaling Pathway in a Human Xenograft Murine Model |
| PMC3534848__F8 | A proposed mechanism by which hyperaldosteronism decreases pulmonary endothelial eNOS activation and NO• generation in PAH |
| PMC3534992__F7 | MiR-146b function in IEC-6 cells mediating TGFB signaling |
| PMC3534995__F2 | Canonical pathway representing LPS/IL-1-mediated inhibition of RXR function obtained by IPA from the analysis of HT29 data set |
| PMC3534995__F3 | Canonical pathway representing NRF2-mediated oxidative stress response obtained by IPA from the analysis of SW480 data set |
| PMC3535180__F1 | Elevated immune-inflammatory signaling in mood disorders: a new therapeutic target? |
| PMC3535184__F4 | Ingenuity pathway analysis reveals the close relationship between 14 of 17 of most relevant genes in rectal cancer |
| PMC3535349__F1 | Iron homeostasis in absorptive enterocytes, macrophages, erythroblasts, and hepatocytes and its routes of circulation in the organism |
| PMC3535349__F2 | Iron transport across the placenta (syncytiotrophoblasts) |
| PMC3535427__F1 | Targeting 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) for colorectal cancer prevention and treatment |
| PMC3535741__F1 | PI3K/AKT/GSK3/mTOR signaling |
| PMC3535856__F6 | Proposed mechanism for MCME-mediated inhibition against migration of CL1 cells |
| PMC3536145__F7 | GXM-mediated inhibition of LPS-induced signal |
| PMC3536146__F8 | Pathway representation of canonical and Pyk2-mediated TLR9 signaling |
| PMC3536147__F3 | Identification of Burkholderia cenocepacia Strain H111 Virulence Factors Using Nonmammalian Infection Hosts |
| PMC3536343__F1 | MTORC1 signaling to the translational machinery |
| PMC3536343__F4 | MAPK signaling to the translational machinery |
| PMC3536347__F1 | Pharmacologic inhibitors of the Wnt/Beta-catenin signaling pathway and known interactions with pathway components (see for references) |
| PMC3536347__F2 | Pharamcologic activators and enhancers of the Wnt/Beta-catenin signaling pathway and known interactions with pathway components (see for references) |
| PMC3536591__F2 | Ingenuity pathway analysis (IPA) top network that incorporates 9 genes identified as differentially methylated between methotrexate-naïve cases and controls by HM27 analysis |
| PMC3536698__F8 | IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling |
| PMC3537922__F1 | Unique host defense pathway: TRIF mediates both antiviral and antibacterial immune responses |
| PMC3538326__F7 | Proposed mechanisms of the reduced activation of G3139 in RIT-INPs |
| PMC3538421__F3 | Summary of P450 enzymes in cholesterol and bile acid biosynthesis |
| PMC3538421__F5 | Diagram showing the fundamental steps and P450 enzymes involved in vitamin D biosynthesis and degradation pathway |
| PMC3538588__F8 | Systems Biology Approach Reveals Genome to Phenome Correlation in Type 2 Diabetes |
| PMC3538603__F8 | Neural Stem Cell Death, Survival, and Differentiation in Response to Partial FGF-2 and EGF Deprivation. |
| PMC3538647__F1 | Metabolic map of the purine biosynthetic pathway |
| PMC3539134__F2 | Inhibition of insulin signaling pathway by SOCS1 and SOCS3 |
| PMC3539150__F1 | Schematic diagram illustrating the specific cascade and signaling pathway in LPS-primed macrophages stimulated with MSU, silica, or alum salt crystals |
| PMC3539252__F3 | Upregulated HCV gene signature is enriched for interferon (IFN) pathway genes |
| PMC3539261__F2 | Initiation of the inflammatory response to monosodium urate crystals (MSU) by the innate immune system |
| PMC3539299__F1 | The phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt pathway and its relationship to the androgen receptor (AR) based on the results of three papers published recently by the laboratories of Charles Sawyers, Damu Tang and Hong Wu |
| PMC3539509__F2 | TLR4 signaling pathway: TLR4 is localized on cell surface for ligand recognition and activates both MyD88-dependent pathway and TRIF-dependent pathway |
| PMC3539548__F1 | Host cell machinery gets activated during influenza infection and leads to trigger Signaling pathways |
| PMC3539662__F1 | Kaposi sarcoma-associated herpesvirus K1 activates PI3K/AKT/mTOR signaling thereby activating protein synthesis and survival pathways, while inhibiting apoptotic pathways |
| PMC3539662__F2 | Kaposi sarcoma-associated herpesvirus vGPCR broadly activates PI3K and MAPK pathways, leading to increased production of cytokines and growth factors, with a concurrent increase in cell proliferation, and inhibition of apoptotic pathways |
| PMC3539736__F3 | PI3K Signaling in B and T Lymphocytes: New Developments and Therapeutic Advances |
| PMC3539739__F1 | Oncogenic Transcription Factors: Cornerstones of Inflammation-Linked Pancreatic Carcinogenesis |
| PMC3539742__F2 | Autophagy and apoptosis- what's the connection? |
| PMC3539824__F2 | Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders |
| PMC3539910__F2 | Carcinogenesis of colorectal cancer cells and role of different miRNAs in cancer pathways |
| PMC3539919__F2 | Simplified carbon metabolic network |
| PMC3539953__F5 | Representation of the "Interferon Signaling" and "Toll-like Receptor Signaling" pathways |
| PMC3540089__F1 | PORPHOBILINOGEN DEAMINASE Deficiency Alters Vegetative and Reproductive Development and Causes Lesions in Arabidopsis |
| PMC3540170__F4 | Immunoregulatory role of anchored cAMP signaling in T cells |
| PMC3540819__F1 | Main signaling pathways involved in thyroid carcinogenesis are the MAPK and PI3K-AKT pathway (reproduced with permission) [] |
| PMC3540836__F1 | Experimentally supported and inferred factors of Drosophila triacylglycerol synthesis and mobilization at lipid storage droplets |
| PMC3540890__F1 | Biosynthetic pathway of prostaglandins |
| PMC3540985__F1 | CYTOKINES, INFLAMMATION AND COLON CANCER |
| PMC3541025__F1 | Autoinflammatory Disease Reloaded: A Clinical Perspective |
| PMC3541122__F6 | MiR-29 family is involved in multiple cellular processes |
| PMC3541196__F3 | Dysregulation of the cell cycle pathway during tumor progression |
| PMC3541267__F3 | Signaling pathways driving mesenchymal stem cells to differentiate into lineages found in reparative disorders |
| PMC3541279__F2 | Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury |
| PMC3541279__F5 | Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury |
| PMC3541283__F7 | FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway |
| PMC3541304__F1 | Protective autophagy induced by RBX1/ROC1 knockdown or CRL inactivation via modulating the DEPTOR-MTOR axis |
| PMC3541634__F1 | Schematic of TGFB1 signaling pathway and its regulation |
| PMC3541667__F5 | Hypothetic model explaining how KDM6 may contribute to definitive endoderm differentiation |
| PMC3542205__F5 | Illustration of the expression levels of enzymes within the glycolytic pathway and major connections in the C |
| PMC3542528__F4 | Protein network analysis of hits reveals multiple connections between signaling molecules and Golgi proteins |
| PMC3542528__F5 | Various subnetworks of signaling molecules that regulate Golgi structure |
| PMC3542934__F1 | TGFB signalling pathway |
| PMC3542954__F1 | Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosisEBV infection disrupts normal cell death and survival pathways in various human tumor cells, including lymphocytes, fibroblasts, and epithelial cells |
| PMC3543073__F2 | Three examples of chromatin-modifying complexes and their mode of action |
| PMC3543073__F4 | Bacterial nucleomodulins targeting chromatin |
| PMC3543090__F4 | MicroRNA-182-5p targets a network of genes involved in DNA repair. |
| PMC3543090__F8 | Model showing the effect of miR-182-5p on the DNA repair pathway |
| PMC3543749__F1 | Insulin/IGF-1 signaling pathway |
| PMC3543749__F2 | Telomere maintenance pathway |
| PMC3543845__F2 | Top network, "DNA Replication, Recombination, and Repair, Gene Expression, Cancer", formed by genes exhibiting altered expression in MLT-pretreated MCF-7 cells upon MMS exposure relative to untreated MMS-exposed cells |
| PMC3544113__F1 | Main deregulated signaling pathways in PMBCL |
| PMC3544185__F6 | Complex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-Stable Colorectal Cancer. |
| PMC3544293__F2 | MTOR signaling pathway |
| PMC3544567__F2 | Differentially expressed genes within the Wnt Signalling pathway |
| PMC3544722__F9 | Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase |
| PMC3544775__F3 | Laminin-211 in skeletal muscle function |
| PMC3544784__F1 | Insight into the role of CRMP2 (collapsin response mediator protein 2) in T lymphocyte migration |
| PMC3545297__F1 | Energy metabolism in a typical mammalian cell |
| PMC3545532__F2 | Model depicting the canonical Nrf2 stress response pathway in each of the different phases: basal, preinduction, induction, postinduction |
| PMC3545710__F5 | Suggested pathway |
| PMC3545835__F1 | Principal platelet membrane receptors and signal transduction pathways |
| PMC3545869__F7 | Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos |
| PMC3545927__F6 | High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome |
| PMC3546058__F1 | DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the omega-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways |
| PMC3546345__F5 | Vascular complications of diabetes: mechanisms of injury and protective factors |
| PMC3546685__F1 | Short-patch (SP-) and long-patch base excision repair (LP-BER) sub-pathways |
| PMC3546740__F2 | Simplified schematic overview of the biosynthesis of the main secondary metabolites stored and/or secreted by tomato glandular trichome cells |
| PMC3546894__F1 | Cytokine regulation of immune response cell phases through gender specific pathways |
| PMC3546980__F7 | Irradiated Riboflavin Diminishes the Aggressiveness of Melanoma In Vitro and In Vivo |
| PMC3547105__F1 | The autotaxin-LPA-LPA1pathway |
| PMC3547110__F3 | Amplifying phase |
| PMC3547332__F5 | MicroRNA involvement in the inflammation, innate immunity, and oxidative stress pathways in AD and cancer |
| PMC3547545__F1 | An illustration of the IIF pathway genes.Notes: Arrows indicate the direction of signal transduction |
| PMC3547636__F2 | G Protein-coupled Receptor FPR1 as a Pharmacologic Target in Inflammation and Human Glioblastoma |
| PMC3547893__F1 | Interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility |
| PMC3547902__F2 | Autocrine functions of VEGF in breast tumor cells |
| PMC3547956__F6 | Transcriptional and Gene Regulatory Network of Lactococcus lactis MG1363 during Growth in Milk |
| PMC3548018__F2 | Integrated scheme for MIF expression, signal transduction and regulation of glucocorticoid immunosuppression and cell survival |
| PMC3548065__F6 | Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 (MK2) inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity |
| PMC3548163__F2 | Modes of action of environmental risk factors for autism at excitatory synapses in the CNS |
| PMC3548172__F3 | Cooperation of esBAF and PRC2 during pluripotency maintenance |
| PMC3548426__F1 | Telomere syndromes |
| PMC3548977__F1 | Itraconazole and arsenic trioxide inhibit hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists |
| PMC3549263__F3 | Low-dose radiation responsive genes linked to carcinogenesis |
| PMC3549305__F4 | GLUTATHIONE SYNTHESIS |
| PMC3549317__F1 | Lipid synthesis in yeast |
| PMC3549334__F7 | Ras activation by •NO-mediated processes in pancreatic cancer |
| PMC3549535__F3 | Innate immune stimulation by LPS positively impacts T cell priming |
| PMC3549669__F6 | STING Specifies IRF3 phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway |
| PMC3549672__F2 | Ubiquitination in Signaling to and Activation of IKK |
| PMC3549672__F3 | Ubiquitination in Signaling to and Activation of IKK |
| PMC3549674__F1 | New and emerging treatments for estrogen receptor-positive breast cancer: focus on everolimus. |
| PMC3551337__F2 | Major pathogenic lesions in MCL |
| PMC3551337__F3 | CRM1 regulates the PI3K signaling pathway in MCL |
| PMC3551464__F1 | Control of cell adhesion during neuronal migration |
| PMC3551738__F3 | Network analysis of known SLE-associated genes |
| PMC3552145__F10 | PGN-induced miR-132 and miR-212 in TLR signaling |
| PMC3552307__F1 | Double-stranded and single-stranded RNA signaling pathway |
| PMC3552454__F4 | Advances in graft-versus-host disease biology and therapy |
| PMC3552512__F3 | Oncogenic signals regulate each stage of translation |
| PMC3552779__F1 | Aerobic glycolysis, the citric acid cycle, and key glycolytic shunts |
| PMC3552883__F8 | Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells |
| PMC3552884__F8 | Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells |
| PMC3552942__F1 | Phosphatidylinositol 3-kinase (PI3K) pathway activation |
| PMC3553295__F3 | Cocaine and Withdrawal on the Mouse Nucleus Accumbens Transcriptome |
| PMC3553500__F7 | NleB, a bacterial effector with glycosyltransferase activity targets GADPH function to inhibit NFKB activation |
| PMC3553670__F3 | Signal transduction pathways and activation of the innate immune response |
| PMC3553975__F6 | Subnetworks identified from (a) Wang et al |
| PMC3553975__F8 | Subnetworks identified from (a) Loi et al |
| PMC3554122__F1 | Summary of checkpoint factors |
| PMC3554339__F1 | Actions of Nec-1 and its derivatives in a mouse system |
| PMC3554558__F1 | Putative role of VHL-HIF-EPO pathway in RCC progression |
| PMC3554567__F4 | Integration of Nodal and BMP Signals in the Heart Requires FoxH1 to Create Left-Right Differences in Cell Migration Rates That Direct Cardiac Asymmetry. |
| PMC3554623__F2 | Battle between Rotavirus and Its Host for Control of the Interferon Signaling Pathway |
| PMC3554769__F1 | Mathematical Model for MicroRNA in Lung Cancer |
| PMC3555197__F1 | LXRs and prostate physiology: potential beneficial actions of LXRs over prostate cancer |
| PMC3555201__F3 | HMGB1 in the tumor microenvironment and hypothesis of HMGB1 functioning via NF-kB and epigenetic pathways |
| PMC3555235__F4 | Predicted pathways by the Ingenuity Pathway Analysis software (IPA) according to microarrays results in peripheral blood mononuclear cells (PBMCs) |
| PMC3555267__F2 | Typical MAPK signaling pathway |
| PMC3555518__F1 | Mechanism of miRNA expression and/or function perturbation |
| PMC3556263__F1 | Molecular pathways affected by CR and irradiation |
| PMC3556327__F4 | Cholesterol biosynthesis theme analysis |
| PMC3556575__F5 | Pathways of relationships identified by feeding gene expression patterns identified in erythroid progenitors to the Ingenuity software |
| PMC3556981__F5 | Analysis of Central Metabolic Pathway Gene Expression with Compartmentalization Information.Heat maps in boxes indicate the expression of individual genes, and the chart plots indicate the aggregate expression levels of the pathway genes |
| PMC3557298__F4 | mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage |
| PMC3557433__F1 | Effector intercrossing network under physiological condition |
| PMC3557440__F4 | Schematic overview of the homologous recombination (HR) pathway |
| PMC3557799__F3 | Structures of Get3, Get4, and Get5 Provide New Models for TA Membrane Protein Targeting |
| PMC3558412__F1 | Diagrammatic overview of the late stages of the HIV life-cycle |
| PMC3558460__F1 | Signal activation of human somatostatin receptor subtype-2 by membrane-displayed somatostatin |
| PMC3558493__F8 | ErbB2-Dependent Chemotaxis Requires Microtubule Capture and Stabilization Coordinated by Distinct Signaling Pathways |
| PMC355851__F8 | Proposed model for the observed inhibitory effects of Alpha-catulin and Alpha-catenin on the activation of cyclin D1 transcription |
| PMC355855__F10 | Models for repression of TGFB signaling by the Smurf-Smad7 complex and reactivation of TGFB signaling by the Jab1/CSN5-Smad7 complex |
| PMC3558831__F6 | PIAs recapitulate the activity of two tumor suppressors that converge on mTOR |
| PMC3558870__F1 | The potential disruption of hepatic GH signaling pathways by MC |
| PMC3559342__F3 | Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin |
| PMC3559342__F4 | Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin |
| PMC3559784__F5 | The Carcinogenic Liver Fluke, Clonorchis sinensis: New Assembly, Reannotation and Analysis of the Genome and Characterization of Tissue Transcriptomes |
| PMC3559989__F6 | Bayesian regulatory network and optimal regulatory pathway of p42.3 protein |
| PMC3560328__F2 | DNA interstrand crosslink repair and cancer |
| PMC3560328__F3 | DNA interstrand crosslink repair and cancer |
| PMC3560328__F4 | DNA interstrand crosslink repair and cancer |
| PMC3560376__F2 | The TLR9-Notch ligand (dll4) on Mycobacterium-dependent granuloma formation |
| PMC3560469__F2 | Angiotensins in the RAS |
| PMC3560666__F7 | Pathway in MAS and differentially expressed genes: as shown in Figure, IGSF4, PTPRC (CD45) and CD3D belong to a family of cell surface adhesion molecules |
| PMC3560853__F3 | Scheme showing the potential molecular events induced in cancer cells in the hypoxic tumour microenvironment |
| PMC3561014__F2 | Adjustments in root metabolism promote acclimation to deficiency |
| PMC3561376__F5 | Whole Genome Gene Expression Analysis Reveals CasiopeÃxadna-Induced Apoptosis Pathways |
| PMC3561376__F6 | Whole Genome Gene Expression Analysis Reveals CasiopeÃxadna-Induced Apoptosis Pathways |
| PMC3561517__F8 | Overview of the recruitment and modification of PCNA and Pol D by RNF8 involving different DNA damage pathways |
| PMC3561537__F6 | Scheme of EGFR signaling pathway activated by NEU3-induced GM3 reduction |
| PMC3561559__F9 | Schematic model of autoregulation of BMI1 |
| PMC3561661__F1 | Activation and function of PI3K/Akt signaling in CD8 T cell |
| PMC3561661__F2 | Orchestration of CD8 T cell differentiation by the PI3K/Akt pathway |
| PMC3561798__F6 | Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis |
| PMC3561841__F1 | Why stress is BAD for cancer patients |
| PMC3562086__F1 | Connecting the Insulin pathway to the Drosophila autophagy machinery |
| PMC3562183__F2 | Expression Microarray Meta-Analysis Identifies Genes Associated with Ras/MAPK and Related Pathways in Progression of Muscle-Invasive Bladder Transition Cell Carcinoma |
| PMC3562241__F6 | Ihh and Runx2/Runx3 Signaling Interact to Coordinate Early Chondrogenesis: A Mouse Model |
| PMC3562293__F2 | Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities |
| PMC3562300__F6 | Pro- and anti-apoptotic effects of p53 in cisplatin-treated human testicular cancer are cell context-dependent |
| PMC3562341__F4 | Accumulation of Splice Variants and Transcripts in Response to PI3K Inhibition in T Cells |
| PMC3562392__F3 | Cytoscape diagram of the functional interaction network representing proteins modulation in Pt1 interstitial fluid |
| PMC3562403__F2 | Phosphatidylinositol (PtdIns) phosphates, PtdIns(4,5)P2 and PtdIns(3,4,5)P3, are key signaling molecules in lymphocyte activation |
| PMC3562404__F2 | Biochemical relationships between the CDP-choline pathway of PtdCho synthesis, the degradation of PtdCho, and general phospholipid metabolism in mammals |
| PMC3562414__F2a | Surfactant phospholipid metabolism |
| PMC3562627__F2 | EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer |
| PMC3562679__F1 | Lipopolysaccharide (endotoxin) signaling pathway |
| PMC3562715__F2 | Oncogenic pathways in ABC-DLBCLThe stimulation of several surface receptors, including the B-cell receptor (BCR), CD40 or Toll-like receptors, triggers signaling cascades resulting in the activation of the NF-kB pathway |
| PMC3563076__F2 | Molecules involved during pancreatic development |
| PMC3563272__F4 | Eukaryotic Phospholipid Synthesis and Editing.G3P produced by GPDH is converted to PA by sequential acylation reactions regulated by GPAT and LPAAT |
| PMC3563405__F1 | represents the melanin synthesis in human, plants, fungi and bacteria starting from tyrosine whereas; (B & C) shows melanogenesis from secondary metabolites in fungi and bacteria respectively |
| PMC3563505__F6 | Functional partners of RB1 protein through STRING database |
| PMC3563611__F8 | Candidate miRNAs target genes involved in cell growth, survival, migration, and cell cycle progression |
| PMC3563666__F4 | Altered Cytokine Gene Expression in Peripheral Blood Monocytes across the Menstrual Cycle in Primary Dysmenorrhea: A Case-Control Study |
| PMC3564018__F10 | Stress-suppressed genes involved in antigen presentation and synapse formation |
| PMC3564018__F7 | Transcription factors predicted to be inhibited by battlefield-like stressors and their targets among stress-modulated genes |
| PMC3564224__F2 | Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47 |
| PMC3564490__F3 | Proposed alternative pathway of feto-placental androgen synthesis from 17-hydroxypregnenolone |
| PMC3564524__F10 | Novel signaling pathways involved in apo(a)-mediated effects on vascular endothelial cells |
| PMC3564914__F1 | Transcriptome analysis of bitter acid biosynthesis and precursor pathways in hop (Humulus lupulus) |
| PMC3565070__F3 | Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections |
| PMC3565104__F4 | Proposed model for progesterone and retinoid action in endometrium and endometriosis |
| PMC3565105__F1 | Hypothetical model illustrates the E2-ERA signaling pathway involving both genomic and extranuclear signaling pathways |
| PMC3565214__F1 | Major oncogenic signaling pathway alterations in urothelial carcinoma |
| PMC3565216__F1 | Phosphatidic Acid Plays a Central Role in the Transcriptional Regulation of Glycerophospholipid Synthesis in Saccharomyces cerevisiae |
| PMC3565254__F2 | Pathways involved in endocrine resistance |
| PMC3565264__F4a | Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct. |
| PMC3565315__F1 | Overview of the Hedgehog signaling pathway: a simplified model for Hh signaling in mammalian cells |
| PMC3565315__F2 | Overview about currently tested Hedgehog pathway inhibitors and their mode of action |
| PMC3565434__F8 | Schematic diagram of proposed CD44-regulated signaling pathway |
| PMC3565545__F10 | CHEK kinase pathway showing the role of CHEK proteins in cell cycle checkpoint control, and crosstalk with other pathways notably the P53 and BRCA pathways.Notes: Double circles indicate complex interactions involving multiple genes |
| PMC3565545__F9 | BRCA pathway showing the role of BRCA1 in DNA damage response and crosstalk with other |
