SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs Dataset

Description Phosphorylation levels of proteins in cell lines following drug treatment
Measurement protein phosphorylation by SILAC
Association protein-drug associations by differential phosphorylation of protein following treatment of cells with drug
Category proteomics
Resource SILAC Phosphoproteomics
Last Updated 2015 Apr 06
Stats
  1. 2770 genes
  2. 23 drug perturbations
  3. 5808 gene-drug perturbation associations

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drug perturbation Gene Sets

23 sets of proteins differentially phosphorylated following drug perturbations from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

Gene Set Description
10uM_gefitinib vs ctrl_KG-1 (Human) [22115753] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
LS_30min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS_90min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS+LS_90min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
Rapamycin vs Ctrl_Exp1_MEFs (Mouse) [21659605] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
50nM_dasatinib vs ctrl_K562 (Human) [19651622] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS+LS_10min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS_10min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS_30min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
5nM_dasatinib vs ctrl_K562 (Human) [19651622] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS+LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
4h_cisplatin vs ctrl_mESC (Mouse) [22006019] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
metaphase_anaphase_telophase_15min_noscapine_release vs ctrl_HeLa (Human) [19691289] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
Rapamycin vs Ctrl Exp2 MEFs (Mouse) [21659605] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
LS_90min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
10uM_erlotinib vs ctrl_KG-1 (Human) [22115753] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
HS+LS_30min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
Rapamycin vs Ctrl_Exp2_MEFs (Mouse) [21659605] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
10min_PPase_inhibitors vs ctrl_Hepa1-6 (Mouse) [18846507] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
metaphase_anaphase_telophase_60min_noscapine_release vs ctrl_HeLa (Human) [19691289] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]
LS_10min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]]