SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations Dataset

Description Phosphorylation levels of proteins in cell lines following genetic perturbation (knockdown, knockout, over-expression, mutation)
Measurement protein phosphorylation by SILAC
Association protein-gene associations by differential phosphorylation of protein following genetic perturbation of cells
Category proteomics
Resource SILAC Phosphoproteomics
Last Updated 2015 Apr 06
Stats
  1. 203 genes
  2. 10 gene perturbations
  3. 840 gene-gene perturbation associations

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Visualizations

  • Attribute Similarity

  • Gene Attribute

  • Gene Similarity

gene perturbation Gene Sets

10 sets of proteins differentially phosphorylated following gene perturbations from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations dataset.

Gene Set Description
0min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
10min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
2min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
3min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
5min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
7min_cross-link_ZAP-70_null vs reconstituted_Jurkat (Human) [19605366] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
basal_PTP1B_KO vs wt_MEF (Mouse) [18515860] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
EGF_PTP1B_KO vs wt_MEF (Mouse) [18515860] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
PDGF_PTP1B_KO vs wt_MEF (Mouse) [18515860] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]
starvation_PTP1B_KO vs wt_MEF (Mouse) [18515860] gene perturbation identified as [gene perturbation]_[cell line] ([organism]) [[publication PMID]]