Wikipathways Pathways Dataset

Description sets of proteins participating in pathways from Wikipathways
Measurement association by literature curation
Association protein-pathway associations from curated pathways
Category structural or functional annotations
Resource Wikipathways
Last Updated 2014 Dec 17
  1. 6093 genes
  2. 427 pathways
  3. 22242 gene-pathway associations

Data Access



  • Attribute Similarity

  • Gene Attribute

  • Gene Similarity

pathway Gene Sets

427 sets of proteins participating in pathways from the Wikipathways Pathways dataset.

Gene Set Description
ACE Inhibitor Pathway(Homo sapiens)
ACE Inhibitor Pathway(Mus musculus)
Acetylcholine Synthesis(Homo sapiens)
Acetylcholine Synthesis(Mus musculus)
Adipogenesis genes(Mus musculus)
Adipogenesis(Homo sapiens)
Aflatoxin B1 metabolism(Homo sapiens)
Aflatoxin B1 metabolism(Mus musculus)
AGE/RAGE pathway(Homo sapiens)
Alanine and aspartate metabolism(Homo sapiens)
Alanine and aspartate metabolism(Mus musculus)
Allograft Rejection(Homo sapiens)
Alpha 6 Beta 4 signaling pathway(Homo sapiens)
Alpha6-Beta4 Integrin Signaling Pathway(Mus musculus)
Alzheimers Disease(Homo sapiens)
Alzheimers Disease(Mus musculus)
Amino acid conjugation of benzoic acid(Homo sapiens)
Amino acid conjugation of benzoic acid(Mus musculus)
Amino Acid metabolism(Mus musculus)
AMPK Signaling(Homo sapiens)
Amyotrophic lateral sclerosis (ALS)(Homo sapiens)
Androgen receptor signaling pathway(Homo sapiens)
Angiogenesis(Homo sapiens)
Apoptosis Modulation and Signaling(Homo sapiens)
Apoptosis Modulation by HSP70(Homo sapiens)
Apoptosis Modulation by HSP70(Mus musculus)
Apoptosis(Homo sapiens)
Apoptosis(Mus musculus)
Apoptosis-related network due to altered Notch3 in ovarian cancer(Homo sapiens)
Arachidonate Epoxygenase Epoxide Hydrolase(Mus musculus)
Arachidonate Epoxygenase / Epoxide Hydrolase(Homo sapiens)
Arrhythmogenic Right Ventricular Cardiomyopathy(Homo sapiens)
Aryl Hydrocarbon Receptor(Homo sapiens)
Arylamine metabolism(Homo sapiens)
Arylhydrocarbon receptor (AhR) signaling pathway(Homo sapiens)
ATM Signaling Pathway(Homo sapiens)
B Cell Receptor Signaling Pathway(Homo sapiens)
BDNF signaling pathway(Homo sapiens)
Benzo(a)pyrene metabolism(Homo sapiens)
Biogenic Amine Synthesis(Homo sapiens)
Biogenic Amine Synthesis(Mus musculus)
Blood Clotting Cascade(Homo sapiens)
Blood Clotting Cascade(Mus musculus)
BMP Signalling and Regulation(Homo sapiens)
Butyrate-induced histone acetylation(Homo sapiens)
Calcium Regulation in the Cardiac Cell(Homo sapiens)
Calcium Regulation in the Cardiac Cell(Mus musculus)
Cardiac Hypertrophic Response(Homo sapiens)
Cardiac Progenitor Differentiation(Homo sapiens)
Catalytic cycle of mammalian FMOs(Homo sapiens)
Cell Cycle(Homo sapiens)
Chemokine signaling pathway(Mus musculus)
Cholesterol Biosynthesis(Homo sapiens)
Cholesterol Biosynthesis(Mus musculus)
Codeine and Morphine Metabolism(Homo sapiens)
Colchicine Metabolic Pathway(Homo sapiens)
Complement Activation, Classical Pathway(Homo sapiens)
Complement Activation, Classical Pathway(Mus musculus)
Complement and Coagulation Cascades(Homo sapiens)
Complement and Coagulation Cascades(Mus musculus)
Cori Cycle(Homo sapiens)
Corticotropin-releasing hormone(Homo sapiens)
Cytokines and Inflammatory Response (BioCarta)(Mus musculus)
Cytokines and Inflammatory Response(Homo sapiens)
Cytoplasmic Ribosomal Proteins(Homo sapiens)
Cytoplasmic Ribosomal Proteins(Mus musculus)
Delta-Notch Signaling Pathway(Mus musculus)
Deregulation of Rab and Rab Effector Genes in Bladder Cancer(Homo sapiens)
Diclofenac Metabolic Pathway(Homo sapiens)
Differentiation Pathway(Homo sapiens)
Diurnally Regulated Genes with Circadian Orthologs(Homo sapiens)
Diurnally Regulated Genes with Circadian Orthologs(Mus musculus)
DNA Damage Response (only ATM dependent)(Homo sapiens)
DNA Damage Response(Homo sapiens)
DNA Replication(Homo sapiens)
DNA Replication(Mus musculus)
Dopamine metabolism(Homo sapiens)
Dopminergic Neurogenesis(Homo sapiens)
Dopminergic Neurogenesis(Mus musculus)
Drug Induction of Bile Acid Pathway(Homo sapiens)
EBV LMP1 signaling(Homo sapiens)
EBV LMP1 signaling(Mus musculus)
Effects of Nitric Oxide(Homo sapiens)
EGF/EGFR Signaling Pathway(Homo sapiens)
EGFR1 Signaling Pathway(Mus musculus)
Eicosanoid Synthesis(Homo sapiens)
Eicosanoid Synthesis(Mus musculus)
Electron Transport Chain(Homo sapiens)
Electron Transport Chain(Mus musculus)
Endochondral Ossification(Homo sapiens)
Endochondral Ossification(Mus musculus)
Endothelin Pathways(Homo sapiens)
EPO Receptor Signaling(Homo sapiens)
EPO Receptor Signaling(Mus musculus)
ErbB Signaling Pathway(Homo sapiens)
ErbB signaling pathway(Mus musculus)
ESC Pluripotency Pathways(Mus musculus)
Estrogen metabolism(Homo sapiens)
Estrogen metabolism(Mus musculus)
Estrogen signaling pathway(Homo sapiens)
Estrogen signalling(Mus musculus)
Eukaryotic Transcription Initiation(Homo sapiens)
Eukaryotic Transcription Initiation(Mus musculus)
Exercise-induced Circadian Regulation(Mus musculus)
Extracellular vesicle-mediated signaling in recipient cells(Homo sapiens)
FAS pathway and Stress induction of HSP regulation(Homo sapiens)
FAS pathway and Stress induction of HSP regulation(Mus musculus)
Fatty Acid Beta Oxidation(Homo sapiens)
Fatty Acid Beta Oxidation(Mus musculus)
Fatty Acid Biosynthesis(Homo sapiens)
Fatty Acid Biosynthesis(Mus musculus)
Fatty Acid Omega Oxidation(Homo sapiens)
Fatty Acid Omega Oxidation(Mus musculus)
Fatty acid oxidation(Mus musculus)
Felbamate Metabolism(Homo sapiens)
Fluoropyrimidine Activity(Homo sapiens)
Focal Adhesion(Homo sapiens)
Focal Adhesion(Mus musculus)
Folate Metabolism(Homo sapiens)
Folate-Alcohol and Cancer Pathway(Homo sapiens)
Folic Acid Network(Mus musculus)
FSH signaling pathway(Homo sapiens)
G Protein Signaling Pathways(Homo sapiens)
G Protein Signaling Pathways(Mus musculus)
G1 to S cell cycle control(Homo sapiens)
G1 to S cell cycle control(Mus musculus)
G13 Signaling Pathway(Homo sapiens)
G13 Signaling Pathway(Mus musculus)
Ganglio Sphingolipid Metabolism(Homo sapiens)
Gastric acid production(Homo sapiens)
Gastric cancer network 1(Homo sapiens)
Gastric cancer network 2(Homo sapiens)
Gene regulatory network modelling somitogenesis (Homo sapiens)
Glial Cell Differentiation(Homo sapiens)
Globo Sphingolipid Metabolism(Homo sapiens)
Glucocorticoid & Mineralcorticoid Metabolism(Homo sapiens)
Glucocorticoid & Mineralcorticoid Metabolism(Mus musculus)
Glucuronidation(Homo sapiens)
Glucuronidation(Mus musculus)
Glutathione and one carbon metabolism(Mus musculus)
Glutathione metabolism(Homo sapiens)
Glutathione metabolism(Mus musculus)
Glycerophospholipid Biosynthetic Pathway(Homo sapiens)
Glycine Metabolism(Homo sapiens)
Glycogen Metabolism(Homo sapiens)
Glycogen Metabolism(Mus musculus)
Glycolysis and Gluconeogenesis(Homo sapiens)
Glycolysis and Gluconeogenesis(Mus musculus)
GPCRs, Class A Rhodopsin-like(Homo sapiens)
GPCRs, Class A Rhodopsin-like(Mus musculus)
GPCRs, Class B Secretin-like(Homo sapiens)
GPCRs, Class B Secretin-like(Mus musculus)
GPCRs, Class C Metabotropic glutamate, pheromone(Homo sapiens)
GPCRs, Class C Metabotropic glutamate, pheromone(Mus musculus)
GPCRs, Other(Homo sapiens)
GPCRs, Other(Mus musculus)
Hair Follicle Development: Induction (Part 1 of 3)(Homo sapiens)
Heart Development(Homo sapiens)
Heart Development(Mus musculus)
Hedgehog Signaling Pathway(Homo sapiens)
Hedgehog Signaling Pathway(Mus musculus)
Hematopoietic Stem Cell Differentiation(Homo sapiens)
Heme Biosynthesis(Homo sapiens)
Heme Biosynthesis(Mus musculus)
Histone Modifications(Homo sapiens)
Histone modifications(Mus musculus)
Homologous recombination(Homo sapiens)
Homologous recombination(Mus musculus)
Hypertrophy Model(Homo sapiens)
Hypertrophy Model(Mus musculus)
Hypothetical Network for Drug Addiction(Homo sapiens)
Hypothetical Network for Drug Addiction(Mus musculus)
ID signaling pathway(Homo sapiens)
Id Signaling Pathway(Mus musculus)
IL-1 signaling pathway(Homo sapiens)
IL-1 Signaling Pathway(Mus musculus)
IL-2 Signaling Pathway(Homo sapiens)
IL-3 Signaling Pathway(Homo sapiens)
IL-3 Signaling Pathway(Mus musculus)
IL-4 Signaling Pathway(Homo sapiens)
IL-5 Signaling Pathway(Homo sapiens)
IL-5 Signaling Pathway(Mus musculus)
IL-6 signaling pathway(Homo sapiens)
IL-6 signaling Pathway(Mus musculus)
IL-7 Signaling Pathway(Homo sapiens)
IL-7 Signaling Pathway(Mus musculus)
IL-9 Signaling Pathway(Homo sapiens)
IL-9 Signaling Pathway(Mus musculus)
IL1 and megakaryotyces in obesity(Homo sapiens)
IL17 signaling pathway(Homo sapiens)
Inflammatory Response Pathway(Homo sapiens)
Inflammatory Response Pathway(Mus musculus)
Influenza A virus infection(Homo sapiens)
Insulin Signaling(Homo sapiens)
Insulin Signaling(Mus musculus)
Integrated Breast Cancer Pathway(Homo sapiens)
Integrated Cancer pathway(Homo sapiens)
Integrated Pancreatic Cancer Pathway(Homo sapiens)
Integrin-mediated Cell Adhesion(Homo sapiens)
Integrin-mediated Cell Adhesion(Mus musculus)
Interferon type I signaling pathways(Homo sapiens)
Interleukin-11 Signaling Pathway(Homo sapiens)
Irinotecan Pathway(Homo sapiens)
Irinotecan Pathway(Mus musculus)
Iron Homeostasis(Mus musculus)
Iron metabolism in placenta(Homo sapiens)
Iron uptake and transport(Homo sapiens)
Keap1-Nrf2(Mus musculus)
Kennedy pathway(Mus musculus)
Kit receptor signaling pathway(Homo sapiens)
Kit Receptor Signaling Pathway(Mus musculus)
Leptin and adiponectin(Mus musculus)
Leptin Insulin Overlap(Mus musculus)
Leptin signaling pathway(Homo sapiens)
Lidocaine metabolism(Homo sapiens)
Macrophage markers(Mus musculus)
MAPK Cascade(Homo sapiens)
MAPK Cascade(Mus musculus)
MAPK Signaling Pathway(Homo sapiens)
MAPK signaling pathway(Mus musculus)
Matrix Metalloproteinases(Homo sapiens)
Matrix Metalloproteinases(Mus musculus)
Membrane Trafficking(Homo sapiens)
Metapathway biotransformation(Homo sapiens)
Metapathway biotransformation(Mus musculus)
Metastatic brain tumor(Homo sapiens)
Methylation Pathways(Homo sapiens)
Methylation(Mus musculus)
MicroRNAs in cardiomyocyte hypertrophy(Homo sapiens)
MicroRNAs in Cardiomyocyte Hypertrophy(Mus musculus)
miR-1 in cardiac development(Mus musculus)
miR-targeted genes in adipocytes - TarBase(Homo sapiens)
miR-targeted genes in epithelium - TarBase(Homo sapiens)
miR-targeted genes in leukocytes - TarBase(Homo sapiens)
miR-targeted genes in lymphocytes - TarBase(Homo sapiens)
miR-targeted genes in muscle cell - TarBase(Homo sapiens)
miR-targeted genes in squamous cell - TarBase(Homo sapiens)
mir34a and TGIF2 in osteoclastogenesis(Homo sapiens)
miRNA Biogenesis(Homo sapiens)
miRNA Regulation of DNA Damage Response(Homo sapiens)
miRNA regulation of DNA Damage Response(Mus musculus)
miRNAs involved in DNA damage response(Homo sapiens)
miRs in Muscle Cell Differentiation(Homo sapiens)
Mismatch repair(Homo sapiens)
Mismatch repair(Mus musculus)
Mitochondrial Gene Expression(Homo sapiens)
Mitochondrial Gene Expression(Mus musculus)
Mitochondrial LC-Fatty Acid Beta-Oxidation(Homo sapiens)
Mitochondrial LC-Fatty Acid Beta-Oxidation(Mus musculus)
Monoamine GPCRs(Homo sapiens)
Monoamine GPCRs(Mus musculus)
Monoamine Transport(Homo sapiens)
mRNA Processing(Homo sapiens)
mRNA processing(Mus musculus)
Myometrial Relaxation and Contraction Pathways(Homo sapiens)
Myometrial Relaxation and Contraction Pathways(Mus musculus)
NAD Biosynthesis II (from tryptophan)(Homo sapiens)
Nanoparticle-mediated activation of receptor signaling(Homo sapiens)
Neural Crest Differentiation(Homo sapiens)
Neural retinal development(Mus musculus)
Neurotransmitter Clearance In The Synaptic Cleft(Homo sapiens)
Neurotransmitter Release Cycle(Homo sapiens)
Nicotine Activity on Chromaffin Cells(Homo sapiens)
Nicotine Activity on Dopaminergic Neurons(Homo sapiens)
Nicotine Metabolism(Homo sapiens)
NLR Proteins(Homo sapiens)
NLR Proteins(Mus musculus)
NOD pathway(Homo sapiens)
Non-homologous end joining(Homo sapiens)
Non-homologous end joining(Mus musculus)
Non-odorant GPCRs(Mus musculus)
Notch Signaling Pathway(Homo sapiens)
Notch Signaling Pathway(Mus musculus)
Nuclear Receptors in Lipid Metabolism and Toxicity(Homo sapiens)
Nuclear receptors in lipid metabolism and toxicity(Mus musculus)
Nuclear Receptors(Homo sapiens)
Nuclear Receptors(Mus musculus)
Nucleotide GPCRs(Homo sapiens)
Nucleotide GPCRs(Mus musculus)
Nucleotide Metabolism(Homo sapiens)
Nucleotide Metabolism(Mus musculus)
Odorant GPCRs(Mus musculus)
Oncostatin M Signaling Pathway(Homo sapiens)
One carbon donor(Homo sapiens)
One carbon metabolism and related pathways(Mus musculus)
One Carbon Metabolism(Homo sapiens)
One Carbon Metabolism(Mus musculus)
Orphan GPCRs(Mus musculus)
Osteoblast Signaling(Homo sapiens)
Osteoblast(Mus musculus)
Osteoclast Signaling(Homo sapiens)
Osteoclast(Mus musculus)
Osteopontin Signaling(Homo sapiens)
Ovarian Infertility Genes(Homo sapiens)
Ovarian Infertility Genes(Mus musculus)
Oxidation by Cytochrome P450(Homo sapiens)
Oxidation by Cytochrome P450(Mus musculus)
Oxidative Damage(Mus musculus)
Oxidative phosphorylation(Homo sapiens)
Oxidative phosphorylation(Mus musculus)
Oxidative Stress(Homo sapiens)
Oxidative Stress(Mus musculus)
p38 MAPK Signaling Pathway(Homo sapiens)
p38 MAPK Signaling Pathway(Mus musculus)
Parkin-Ubiquitin Proteasomal System pathway(Homo sapiens)
Parkinsons Disease Pathway(Homo sapiens)
Pathogenic Escherichia coli infection(Homo sapiens)
PCSK9-mediated LDLR degradation(Homo sapiens)
PDGF Pathway(Homo sapiens)
Pentose Phosphate Pathway(Homo sapiens)
Pentose Phosphate Pathway(Mus musculus)
Peptide GPCRs(Homo sapiens)
Peptide GPCRs(Mus musculus)
Peroxisomal beta-oxidation of tetracosanoyl-CoA(Homo sapiens)
Phase I biontransformations, non P450(Mus musculus)
Phase I biotransformations, non P450(Homo sapiens)
Physiological and Pathological Hypertrophy of the Heart(Homo sapiens)
Pilocytic astrocytoma(Homo sapiens)
PluriNetWork(Mus musculus)
PodNet: protein-protein interactions in the podocyte(Mus musculus)
Polyol Pathway(Homo sapiens)
Polyol pathway(Mus musculus)
PPAR signaling pathway(Mus musculus)
Primary Focal Segmental Glomerulosclerosis FSGS(Homo sapiens)
Prostaglandin Synthesis and Regulation(Homo sapiens)
Prostaglandin Synthesis and Regulation(Mus musculus)
Proteasome Degradation(Homo sapiens)
Proteasome Degradation(Mus musculus)
Ptf1a related regulatory pathway(Mus musculus)
Purine metabolism(Mus musculus)
Quercetin and Nf-kB/ AP-1 induced cell apoptosis(Homo sapiens)
RalA downstream regulated genes(Homo sapiens)
RANKL/RANK Signaling Pathway(Homo sapiens)
RB in Cancer(Homo sapiens)
Regulation of Actin Cytoskeleton(Homo sapiens)
Regulation of Actin Cytoskeleton(Mus musculus)
Regulation of Cardiac Hypertrophy by miR-208(Mus musculus)
Regulation of Microtubule Cytoskeleton(Homo sapiens)
Regulation of toll-like receptor signaling pathway(Homo sapiens)
Retinol metabolism(Mus musculus)
RNA interference(Homo sapiens)
Secretion of Hydrochloric Acid in Parietal Cells(Homo sapiens)
Selenium Metabolism and Selenoproteins(Homo sapiens)
Selenium metabolism/Selenoproteins(Mus musculus)
Selenium Micronutrient Network(Homo sapiens)
Selenium Micronutrient Network(Mus musculus)
Semaphorin interactions(Homo sapiens)
Senescence and Autophagy(Homo sapiens)
Serotonin and anxiety(Mus musculus)
Serotonin and anxiety-related events(Mus musculus)
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling(Homo sapiens)
Serotonin Receptor 2 and STAT3 Signaling(Homo sapiens)
Serotonin Receptor 4/6/7 and NR3C Signaling(Homo sapiens)
Serotonin Transporter Activity(Homo sapiens)
SIDS Susceptibility Pathways(Homo sapiens)
SIDS Susceptibility Pathways(Mus musculus)
Signal Transduction of S1P Receptor(Homo sapiens)
Signal Transduction of S1P Receptor(Mus musculus)
Signaling of Hepatocyte Growth Factor Receptor(Homo sapiens)
Signaling of Hepatocyte Growth Factor Receptor(Mus musculus)
Signaling Pathways in Glioblastoma(Homo sapiens)
Small Ligand GPCRs(Homo sapiens)
Small Ligand GPCRs(Mus musculus)
Sphingolipid Metabolism(Homo sapiens)
Spinal Cord Injury(Homo sapiens)
Spinal Cord Injury(Mus musculus)
Splicing factor NOVA regulated synpatic proteins(Mus musculus)
SREBF and miR33 in cholesterol and lipid homeostasis(Homo sapiens)
SREBF and miR33 in cholesterol and lipid homeostasis(Mus musculus)
SREBP signalling(Homo sapiens)
SRF and miRs in Smooth Muscle Differentiation and Proliferation(Homo sapiens)
Statin Pathway(Homo sapiens)
Statin Pathway(Mus musculus)
Steroid Biosynthesis(Homo sapiens)
Steroid Biosynthesis(Mus musculus)
Striated Muscle Contraction(Homo sapiens)
Striated Muscle Contraction(Mus musculus)
Structural Pathway of Interleukin 1 (IL-1)(Homo sapiens)
Sulfation Biotransformation Reaction(Homo sapiens)
Sulindac Metabolic Pathway(Homo sapiens)
Synaptic Vesicle Pathway(Homo sapiens)
Synthesis and Degradation of Ketone Bodies(Homo sapiens)
Synthesis and Degradation of Ketone Bodies(Mus musculus)
T-Cell Receptor and Co-stimulatory Signaling(Homo sapiens)
Tamoxifen metabolism(Homo sapiens)
TarBasePathway(Homo sapiens)
TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer(Homo sapiens)
TCA Cycle(Homo sapiens)
TCA Cycle(Mus musculus)
TCR Signaling Pathway(Homo sapiens)
TFs Regulate miRNAs related to cardiac hypertrophy(Homo sapiens)
TGF Beta Signaling Pathway(Homo sapiens)
TGF Beta Signaling Pathway(Mus musculus)
Thyroxine (Thyroid Hormone) Production(Homo sapiens)
TNF alpha Signaling Pathway(Homo sapiens)
TNF-alpha NF-kB Signaling Pathway(Mus musculus)
Toll Like Receptor signaling(Mus musculus)
Toll-like receptor signaling pathway(Homo sapiens)
TOR Signaling(Homo sapiens)
TP53 Network(Homo sapiens)
Trans-sulfuration and one carbon metabolism(Homo sapiens)
Trans-sulfuration pathway(Homo sapiens)
Transcriptional activation by NRF2(Homo sapiens)
Translation Factors(Homo sapiens)
Translation Factors(Mus musculus)
Triacylglyceride Synthesis(Homo sapiens)
Triacylglyceride Synthesis(Mus musculus)
Tryptophan metabolism(Homo sapiens)
Tryptophan metabolism(Mus musculus)
TSH signaling pathway(Homo sapiens)
TSLP Signaling Pathway(Homo sapiens)
TWEAK Signaling Pathway(Homo sapiens)
Type II diabetes mellitus(Homo sapiens)
Type II interferon signaling (IFNG)(Homo sapiens)
Type II interferon signaling (IFNG)(Mus musculus)
Type III interferon signaling(Homo sapiens)
Urea cycle and metabolism of amino groups(Homo sapiens)
Vitamin A and Carotenoid Metabolism(Homo sapiens)
Vitamin B12 Metabolism(Homo sapiens)
Vitamin D Metabolism(Homo sapiens)
Wnt Signaling Pathway and Pluripotency(Homo sapiens)
Wnt Signaling Pathway and Pluripotency(Mus musculus)
Wnt Signaling Pathway Netpath(Homo sapiens)
Wnt Signaling Pathway NetPath(Mus musculus)
Wnt Signaling Pathway(Homo sapiens)
Wnt Signaling Pathway(Mus musculus)
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)