AEBP1 Gene

Name	AE binding protein 1
Description	This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Adipocyte enhancer‐binding protein 1 (AEBP1) is emerging as a multifunctional regulator with diverse roles in inflammation, lipid metabolism, fibrosis, development, and cancer. In macrophages, AEBP1 acts as a transcriptional repressor that down‐regulates peroxisome proliferator–activated receptor γ1 (PPARγ1) and liver X receptor α (LXRα) activity, thereby suppressing the expression of key cholesterol efflux mediators and promoting foam cell formation and atherogenesis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": " In parallel, AEBP1 enhances inflammatory signaling by interacting with IκBα to facilitate nuclear factor–κB (NF‐κB) activation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " Its functions extend to the extracellular compartment, where the AEBP1 gene product—also known as aortic carboxypeptidase–like protein (ACLP)—associates with collagens and contributes to extracellular matrix organization; genetic alterations in AEBP1 cause connective tissue defects reminiscent of Ehlers–Danlos syndrome, underscoring its essential role in collagen fibril assembly and tissue integrity."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the context of cancer, AEBP1 is frequently overexpressed and has been implicated in driving malignant behaviors across several tumor types. Overexpression in gastric and colon cancers correlates with enhanced cell proliferation, migration, invasion, and epithelial–mesenchymal transition through NF‐κB–mediated pathways"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": ", while in glioblastoma and breast cancer, deregulated AEBP1 influences tumor cell survival and the surrounding microenvironment through similar proinflammatory and pro‐invasive mechanisms."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "13"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Moreover, AEBP1 modulates adipose tissue homeostasis and adipogenesis. By negatively regulating the tumor suppressor PTEN and modulating mitogen‐activated protein kinase activity, AEBP1 promotes preadipocyte proliferation and influences fat accumulation, which in turn has implications for metabolic disorders and obesity‐related pathologies."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": " Finally, recent evidence also highlights a role for AEBP1 in cardiac fibrosis, where its induction in cardiac non‐myocytes is associated with fibrotic remodeling."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "16"}]}, {"type": "t", "text": " Collectively, these studies position AEBP1 as a pivotal molecular nexus that integrates inflammatory signaling, extracellular matrix dynamics, and metabolic regulation with significant impacts on atherosclerosis, fibrotic disease, and cancer.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Amin Majdalawieh, Hyo-Sung Ro "}, {"type": "b", "children": [{"type": "t", "text": "PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucl Recept Signal (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1621/nrs.08004"}], "href": "https://doi.org/10.1621/nrs.08004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20419060"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20419060"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Amin Majdalawieh, Lei Zhang, Ilia V Fuki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0508139103"}], "href": "https://doi.org/10.1073/pnas.0508139103"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16461908"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16461908"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Amin Majdalawieh, Hyo-Sung Ro "}, {"type": "b", "children": [{"type": "t", "text": "LPS-induced suppression of macrophage cholesterol efflux is mediated by adipocyte enhancer-binding protein 1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Biochem Cell Biol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.biocel.2009.01.003"}], "href": "https://doi.org/10.1016/j.biocel.2009.01.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19166963"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19166963"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Oleg Bogachev, Amin Majdalawieh, Xuefang Pan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Adipocyte enhancer-binding protein 1 (AEBP1) (a novel macrophage proinflammatory mediator) overexpression promotes and ablation attenuates atherosclerosis in ApoE (-/-) and LDLR (-/-) mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Med (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2119/molmed.2011.00141"}], "href": "https://doi.org/10.2119/molmed.2011.00141"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21687917"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21687917"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Ming Yuan, Hongjie Fu, Lifen Ren, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Soluble CD40 ligand promotes macrophage foam cell formation in the etiology of atherosclerosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cardiology (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1159/000374105"}], "href": "https://doi.org/10.1159/000374105"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25825037"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25825037"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Amin Majdalawieh, Lei Zhang, Hyo-Sung Ro "}, {"type": "b", "children": [{"type": "t", "text": "Adipocyte enhancer-binding protein-1 promotes macrophage inflammatory responsiveness by up-regulating NF-kappaB via IkappaBalpha negative regulation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Biol Cell (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1091/mbc.e06-03-0217"}], "href": "https://doi.org/10.1091/mbc.e06-03-0217"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17202411"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17202411"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Delfien Syx, Inge De Wandele, Sofie Symoens, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bi-allelic AEBP1 mutations in two patients with Ehlers-Danlos syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddz024"}], "href": "https://doi.org/10.1093/hmg/ddz024"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30668708"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30668708"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Bonna Ith, Jiao Wei, Shaw-Fang Yet, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gene Expr Patterns (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.modgep.2004.11.002"}], "href": "https://doi.org/10.1016/j.modgep.2004.11.002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15749083"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15749083"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Jun-Yan Liu, Lei Jiang, Jia-Jia Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "AEBP1 promotes epithelial-mesenchymal transition of gastric cancer cells by activating the NF-κB pathway and predicts poor outcome of the patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-018-29878-6"}], "href": "https://doi.org/10.1038/s41598-018-29878-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30097586"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30097586"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Yanwei Xing, Zhiqiang Zhang, Fengxu Chi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Carcinog (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mc.23066"}], "href": "https://doi.org/10.1002/mc.23066"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31219650"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31219650"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Jayashree Ladha, Swati Sinha, Vasudeva Bhat, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of genomic targets of transcription factor AEBP1 and its role in survival of glioma cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer Res (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/1541-7786.MCR-11-0488"}], "href": "https://doi.org/10.1158/1541-7786.MCR-11-0488"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22723309"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22723309"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Miho Riku, Shingo Inaguma, Hideaki Ito, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.6788"}], "href": "https://doi.org/10.18632/oncotarget.6788"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26744317"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26744317"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Akira Yorozu, Eiichiro Yamamoto, Takeshi Niinuma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Upregulation of adipocyte enhancer-binding protein 1 in endothelial cells promotes tumor angiogenesis in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cas.14360"}], "href": "https://doi.org/10.1111/cas.14360"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32086986"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32086986"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Hyo-Sung Ro, Lei Zhang, Amin Majdalawieh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Adipocyte enhancer-binding protein 1 modulates adiposity and energy homeostasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Obesity (Silver Spring) (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/oby.2007.569"}], "href": "https://doi.org/10.1038/oby.2007.569"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17299101"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17299101"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Lei Zhang, Shannon P Reidy, Tara E Nicholson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The role of AEBP1 in sex-specific diet-induced obesity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Med (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2119/2005-00021.Ro"}], "href": "https://doi.org/10.2119/2005-00021.Ro"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16307171"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16307171"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Man Rao, Xiliang Wang, Guangran Guo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Basic Res Cardiol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00395-021-00897-1"}], "href": "https://doi.org/10.1007/s00395-021-00897-1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34601654"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34601654"}]}]}]}
Synonyms	ACLP
Proteins	AEBP1_HUMAN
NCBI Gene ID	165
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

AEBP1 has 8,895 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 121 datasets.

Click the + buttons to view associations for AEBP1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

AEBP1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by AEBP1 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of AEBP1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of AEBP1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of AEBP1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of AEBP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of AEBP1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of AEBP1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of AEBP1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of AEBP1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of AEBP1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of AEBP1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of AEBP1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of AEBP1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with AEBP1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of AEBP1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of AEBP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of AEBP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with AEBP1 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of AEBP1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of AEBP1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing AEBP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing AEBP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with AEBP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with AEBP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of AEBP1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with AEBP1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with AEBP1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by AEBP1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving AEBP1 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with AEBP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with AEBP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with AEBP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with AEBP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with AEBP1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at AEBP1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of AEBP1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of AEBP1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing AEBP1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of AEBP1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with AEBP1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.