ANGPT1 Gene

HGNC Family	Fibrinogen C domain containing
Name	angiopoietin 1
Description	This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema. [provided by RefSeq, Aug 2020]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Angiopoietin‐1 (ANGPT1) is a multifunctional growth factor that binds to and activates the endothelial‐specific receptor Tie2 to promote vascular stability and maturation. In the bone marrow vascular niche, ANGPT1–Tie2 signaling helps maintain hematopoietic stem cell (HSC) quiescence by enhancing cellular adhesion to osteoblasts and protecting the HSC compartment from stress."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In acute lung injury, mesenchymal stem cells overexpressing ANGPT1 reduce pulmonary inflammation and almost completely reverse permeability defects, thereby improving alveolar barrier function."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n At the vascular level, ANGPT1 plays a central role in counteracting the permeability‐promoting effects of vascular endothelial growth factor (VEGF). By activating Tie2 at specific subcellular locations—whether at cell–matrix or cell–cell contacts—it triggers downstream signals (for example, via Akt and Erk) that consolidate endothelial adherens junctions and inhibit Src‐mediated phosphorylation and internalization of VE‐cadherin."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": " ANGPT1 also offsets VEGF‐induced angiogenesis and vascular leakage, thereby contributing to vascular remodeling in vivo."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the retina, ANGPT1 is expressed during normal vascular maturation and helps maintain pericyte coverage; its balanced activity is crucial for preventing the pericyte dropout observed in diabetic retinopathy."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " Similarly, ANGPT1 promotes lymphatic endothelial cell proliferation, filopodia formation, and sprouting, all of which contribute to lymphangiogenesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the heart, enhanced ANGPT1 expression is associated with increased coronary capillary density and improved myocardial repair following injury, indicating that ANGPT1‐mediated neovascularization supports cardiac function."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Structural studies demonstrate that ANGPT1 requires multimerization beyond a tetrameric state to effectively activate Tie2, whereas dimeric forms can act as antagonists—underscoring the importance of its modular architecture in mediating its vascular effects."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": " Moreover, mutations in ANGPT1 that impair multimer formation and receptor binding have been linked to hereditary angioedema, highlighting its essential role in maintaining vascular integrity."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In tumors, ANGPT1 contributes to vessel normalization and stabilization. When the effects of Angiopoietin-2 (ANGPT2), a context-dependent modulator that often counteracts ANGPT1, are blocked, unopposed ANGPT1 signaling restores endothelial junction integrity and reduces vascular permeability, thereby mitigating tumor growth."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": " In addition, oncogenic factors such as AEG-1 can upregulate ANGPT1 expression, further promoting angiogenic processes that facilitate tumor invasion."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Collectively, these studies underscore ANGPT1’s critical role as a vascular stabilizer that reinforces endothelial cell survival, junction integrity, and controlled angiogenic remodeling in diverse biological systems—from hematopoietic niches and lung tissue to lymphatic, cardiac, and tumor vasculature. Its ability to counterbalance permeability stimuli and mediate vessel maturation makes ANGPT1 a promising therapeutic target across multiple clinical settings.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Fumio Arai, Atsushi Hirao, Masako Ohmura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cell.2004.07.004"}], "href": "https://doi.org/10.1016/j.cell.2004.07.004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15260986"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15260986"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Shirley H J Mei, Sarah D McCarter, Yupu Deng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Med (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pmed.0040269"}], "href": "https://doi.org/10.1371/journal.pmed.0040269"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17803352"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17803352"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Pipsa Saharinen, Lauri Eklund, Juho Miettinen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Cell Biol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ncb1715"}], "href": "https://doi.org/10.1038/ncb1715"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18425119"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18425119"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Julie Gavard, Vyomesh Patel, J Silvio Gutkind "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Cell (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.devcel.2007.10.019"}], "href": "https://doi.org/10.1016/j.devcel.2007.10.019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18194650"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18194650"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Richard P Visconti, Charlene D Richardson, Thomas N Sato "}, {"type": "b", "children": [{"type": "t", "text": "Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.122109599"}], "href": "https://doi.org/10.1073/pnas.122109599"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12048246"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12048246"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Hans-Peter Hammes, Jihong Lin, Patrick Wagner, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Diabetes (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2337/diabetes.53.4.1104"}], "href": "https://doi.org/10.2337/diabetes.53.4.1104"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15047628"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15047628"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Tuomas Tammela, Anne Saaristo, Marja Lohela, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietin-1 promotes lymphatic sprouting and hyperplasia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2004-08-3327"}], "href": "https://doi.org/10.1182/blood-2004-08-3327"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15746084"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15746084"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Tohru Morisada, Yuichi Oike, Yoshihiro Yamada, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2004-08-3382"}], "href": "https://doi.org/10.1182/blood-2004-08-3382"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15705793"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15705793"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Joerg Heineke, Mannix Auger-Messier, Jian Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI32573"}], "href": "https://doi.org/10.1172/JCI32573"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17975667"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17975667"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Dengshun Miao, Bin He, Andrew C Karaplis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Parathyroid hormone is essential for normal fetal bone formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI14817"}], "href": "https://doi.org/10.1172/JCI14817"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11994406"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11994406"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Samuel Davis, Nick Papadopoulos, Thomas H Aldrich, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Struct Biol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nsb880"}], "href": "https://doi.org/10.1038/nsb880"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12469114"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12469114"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Valeria Bafunno, Davide Firinu, Maria D'Apolito, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutation of the angiopoietin-1 gene (ANGPT1) associates with a new type of hereditary angioedema."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Allergy Clin Immunol (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jaci.2017.05.020"}], "href": "https://doi.org/10.1016/j.jaci.2017.05.020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28601681"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28601681"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Beverly L Falcón, Hiroya Hashizume, Petros Koumoutsakos, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Pathol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2353/ajpath.2009.090391"}], "href": "https://doi.org/10.2353/ajpath.2009.090391"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19815705"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19815705"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Christopher Daly, Alexandra Eichten, Carla Castanaro, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/0008-5472.CAN-12-2064"}], "href": "https://doi.org/10.1158/0008-5472.CAN-12-2064"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23149917"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23149917"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Luni Emdad, Seok-Geun Lee, Zhao Zhong Su, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0910936106"}], "href": "https://doi.org/10.1073/pnas.0910936106"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19940250"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19940250"}]}]}]}
Synonyms	AGPT, AGP1, ANG1
Proteins	ANGP1_HUMAN
NCBI Gene ID	284
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

ANGPT1 has 10,442 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 123 datasets.

Click the + buttons to view associations for ANGPT1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

ANGPT1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ANGPT1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of ANGPT1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of ANGPT1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of ANGPT1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of ANGPT1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ANGPT1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of ANGPT1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ANGPT1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ANGPT1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of ANGPT1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of ANGPT1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of ANGPT1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with ANGPT1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ANGPT1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of ANGPT1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of ANGPT1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with ANGPT1 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of ANGPT1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing ANGPT1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing ANGPT1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with ANGPT1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with ANGPT1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of ANGPT1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with ANGPT1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with ANGPT1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with ANGPT1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with ANGPT1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by ANGPT1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving ANGPT1 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with ANGPT1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with ANGPT1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with ANGPT1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with ANGPT1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with ANGPT1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at ANGPT1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ANGPT1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of ANGPT1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing ANGPT1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with ANGPT1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with ANGPT1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.