{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent studies have revealed that the long non-coding RNA ANKRD10-IT1 plays a significant role in cancer‐related regulatory networks. In one study"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", ANKRD10-IT1 was examined in the context of m6A‐mediated regulation, suggesting that its dysregulation might affect cellular signaling and communication processes. In a subsequent investigation focused on triple‐negative breast cancer (TNBC)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ", ANKRD10-IT1 was identified as one of 10 independent m6A‐related long non‑coding RNAs that were differentially expressed in high‑risk TNBC patients. These studies found that the expression pattern of ANKRD10-IT1, along with its m6A‐related counterparts, contributed to a robust prognostic risk model that predicts overall survival and is linked to pathways involved in cell communication, signaling transduction, and oncogenesis. Collectively, the results suggest that ANKRD10-IT1 is not only a promising biomarker for prognostic assessment but may also actively participate in the regulatory circuits underlying cancer progression.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yu Liu, Liyu Wang, Hengchang Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Prognostic Significance of Metabolic Syndrome and a Related Six-lncRNA Signature in Esophageal Squamous Cell Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Oncol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fonc.2020.00061"}], "href": "https://doi.org/10.3389/fonc.2020.00061"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32133283"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32133283"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Jie Wu, Yan Cai, Gaiping Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A ten N6-methyladenosine-related long non-coding RNAs signature predicts prognosis of triple-negative breast cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Lab Anal (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcla.23779"}], "href": "https://doi.org/10.1002/jcla.23779"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33934391"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33934391"}]}]}]}