ARHGAP26-AS1 Gene

Name ARHGAP26 antisense RNA 1
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n ARHGAP26‐AS1 is a long noncoding RNA that appears to play a multifaceted role in modulating host cell regulatory mechanisms. One study"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "indicates that ARHGAP26‐AS1 is involved in controlling intracellular signaling and cellular architecture, suggesting it may influence processes such as cytoskeletal dynamics and gene expression. In the context of viral infections, particularly COVID‐19, another study"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "highlights the critical roles of angiotensin‐converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in mediating SARS‐CoV‐2 entry into host cells. Emerging evidence suggests that ARHGAP26‐AS1 may modulate the expression or function of these viral entry factors, thereby potentially affecting host cell susceptibility to SARS‐CoV‐2 infection. Together, these findings underscore a dual role for ARHGAP26‐AS1 in both the regulation of fundamental cellular processes and in influencing the host’s response to viral invasion.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yinliang Lu, XueHui Luo, Qi Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Novel Necroptosis-Related lncRNA Signature Predicts the Prognosis of Lung Adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Genet (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fgene.2022.862741"}], "href": "https://doi.org/10.3389/fgene.2022.862741"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35368663"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35368663"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Soudabeh Sabetian, Isabella Castiglioni, Bahia Namavar Jahromi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "In Silico Identification of miRNA-lncRNA Interactions in Male Reproductive Disorder Associated with COVID-19 Infection."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cells (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/cells10061480"}], "href": "https://doi.org/10.3390/cells10061480"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34204705"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34204705"}]}]}]}
NCBI Gene ID 100874239
API
Download Associations
Predicted Functions View ARHGAP26-AS1's ARCHS4 Predicted Functions.
Co-expressed Genes View ARHGAP26-AS1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View ARHGAP26-AS1's ARCHS4 Predicted Functions.

Functional Associations

ARHGAP26-AS1 has 176 functional associations with biological entities spanning 4 categories (disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 9 datasets.

Click the + buttons to view associations for ARHGAP26-AS1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of ARHGAP26-AS1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of ARHGAP26-AS1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of ARHGAP26-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of ARHGAP26-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of ARHGAP26-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of ARHGAP26-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of ARHGAP26-AS1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of ARHGAP26-AS1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of ARHGAP26-AS1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.