ATXN2 Gene

HGNC Family	Ataxins (ATXN), Trinucleotide repeat containing (TNRC)
Name	ataxin 2
Description	This gene belongs to a group of genes that is associated with microsatellite-expansion diseases, a class of neurological and neuromuscular disorders caused by expansion of short stretches of repetitive DNA. The protein encoded by this gene has two globular domains near the N-terminus, one of which contains a clathrin-mediated trans-Golgi signal and an endoplasmic reticulum exit signal. The encoded cytoplasmic protein localizes to the endoplasmic reticulum and plasma membrane, is involved in endocytosis, and modulates mTOR signals, modifying ribosomal translation and mitochondrial function. The N-terminal region of the protein contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues. Intermediate length expansions of this tract increase susceptibility to amyotrophic lateral sclerosis, while long expansions of this tract result in spinocerebellar ataxia-2, an autosomal-dominantly inherited, neurodegenerative disorder. Genome-wide association studies indicate that loss-of-function mutations in this gene may be associated with susceptibility to type I diabetes, obesity and hypertension. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nAtaxin‑2 (ATXN2) is emerging as a multifunctional RNA‐binding protein that plays a central role in post‐transcriptional gene regulation. It directly associates with messenger ribonucleoprotein complexes by assembling with polyribosomes and binding to the poly(A)‑binding protein (PABP) via conserved domains. Such interactions enable ATXN2 to bind mRNAs—both directly (via its Lsm domain) and indirectly (through its PAM2 motif and PABP interaction)—to regulate mRNA stabilization and translation, thereby influencing the expression of key proteins required for normal cellular homeostasis. (."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its role in RNA metabolism, ATXN2 functions as a potent modifier in neurodegenerative disease pathways. Intermediate‐length expansions of its polyglutamine tract have been shown to enhance the toxicity of key RNA‑binding proteins such as TDP‑43 and FUS, thereby promoting stress‑induced caspase activation, aberrant proteolytic cleavage, and aggregation that are characteristic of amyotrophic lateral sclerosis (ALS) and related neurodegenerative disorders. Moreover, genetic studies indicate that structural variations and haplotypes in the ATXN2 gene confer increased risk for conditions including ALS and progressive supranuclear palsy by altering ATXN2’s interaction dynamics and RNA‐processing functions. (."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "12"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond RNA regulation, ATXN2 contributes to other critical cellular pathways including endocytic receptor trafficking, cytoskeletal dynamics, and the modulation of apoptotic sensitivity. It interacts with endocytic regulators—such as endophilin A1/A3—to influence receptor cycling and membrane dynamics, while studies in Drosophila have underscored a conserved role in the regulation of actin filament formation. Furthermore, altered levels of ATXN2 can sensitize cells to apoptotic stimuli, linking its dysregulation not only to neurodegeneration but also to aberrant cell death. (."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "13", "end_ref": "17"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Markus Ralser, Mario Albrecht, Ute Nonhoff, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An integrative approach to gain insights into the cellular function of human ataxin-2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Biol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jmb.2004.11.024"}], "href": "https://doi.org/10.1016/j.jmb.2004.11.024"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15663938"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15663938"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Terrence F Satterfield, Leo J Pallanck "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddl173"}], "href": "https://doi.org/10.1093/hmg/ddl173"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16835262"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16835262"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Guennadi Kozlov, Nozhat Safaee, Angelika Rosenauer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M109.089540"}], "href": "https://doi.org/10.1074/jbc.M109.089540"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20181956"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20181956"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Andrew C Elden, Hyung-Jun Kim, Michael P Hart, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature09320"}], "href": "https://doi.org/10.1038/nature09320"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20740007"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20740007"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Teresa Lee, Yun R Li, Caroline Ingre, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddr045"}], "href": "https://doi.org/10.1093/hmg/ddr045"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21292779"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21292779"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Zhenming Yu, Yongqing Zhu, Alice S Chen-Plotkin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0017951"}], "href": "https://doi.org/10.1371/journal.pone.0017951"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21479228"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21479228"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Owen A Ross, Nicola J Rutherford, Matt Baker, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 repeat-length variation and neurodegeneration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddr227"}], "href": "https://doi.org/10.1093/hmg/ddr227"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21610160"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21610160"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Michael P Hart, Aaron D Gitler "}, {"type": "b", "children": [{"type": "t", "text": "ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.0996-12.2012"}], "href": "https://doi.org/10.1523/JNEUROSCI.0996-12.2012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22764223"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22764223"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Manal A Farg, Kai Y Soo, Sadaf T Warraich, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/dds479"}], "href": "https://doi.org/10.1093/hmg/dds479"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23172909"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23172909"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Chantal Sellier, Maria-Letizia Campanari, Camille Julie Corbier, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO J (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.15252/embj.201593350"}], "href": "https://doi.org/10.15252/embj.201593350"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27103069"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27103069"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Pan P Li, Xin Sun, Guangbin Xia, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Ann Neurol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ana.24761"}], "href": "https://doi.org/10.1002/ana.24761"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27531668"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27531668"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Sharan Paul, Warunee Dansithong, Karla P Figueroa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-018-06041-3"}], "href": "https://doi.org/10.1038/s41467-018-06041-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30194296"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30194296"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Markus Ralser, Ute Nonhoff, Mario Albrecht, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddi321"}], "href": "https://doi.org/10.1093/hmg/ddi321"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16115810"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16115810"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "David Nonis, Mirko H H Schmidt, Simone van de Loo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Signal (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cellsig.2008.05.018"}], "href": "https://doi.org/10.1016/j.cellsig.2008.05.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18602463"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18602463"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Christian Kaehler, Jörg Isensee, Ute Nonhoff, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2-like is a regulator of stress granules and processing bodies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0050134"}], "href": "https://doi.org/10.1371/journal.pone.0050134"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23209657"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23209657"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Jessica N Cooke Bailey, Stephanie J Loomis, Jae H Kang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng.3482"}], "href": "https://doi.org/10.1038/ng.3482"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26752265"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26752265"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Ruprecht Wiedemeyer, Frank Westermann, Isabel Wittke, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Ataxin-2 promotes apoptosis of human neuroblastoma cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.onc.1206150"}], "href": "https://doi.org/10.1038/sj.onc.1206150"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12545161"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12545161"}]}]}]}
Synonyms	ASL13, ATX2, TNRC13
Proteins	ATX2_HUMAN
NCBI Gene ID	6311
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

ATXN2 has 8,285 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 125 datasets.

Click the + buttons to view associations for ATXN2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

ATXN2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ATXN2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of ATXN2 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of ATXN2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of ATXN2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of ATXN2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of ATXN2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ATXN2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of ATXN2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of ATXN2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of ATXN2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with ATXN2 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with ATXN2 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ATXN2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of ATXN2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of ATXN2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of ATXN2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing ATXN2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing ATXN2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing ATXN2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing ATXN2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with ATXN2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with ATXN2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with ATXN2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with ATXN2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with ATXN2 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with ATXN2 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of ATXN2 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by ATXN2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores	diseases involving ATXN2 gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving ATXN2 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with ATXN2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with ATXN2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with ATXN2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with ATXN2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with ATXN2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with ATXN2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at ATXN2 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of ATXN2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of ATXN2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing ATXN2 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.