{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Note: Although the query requests a summary of BARX1‐AS1, the provided abstract (PMID:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "describes the function of FAM83A‐AS1. Based on this abstract, FAM83A‐AS1 is a natural antisense transcript that is markedly upregulated in non–small‐cell lung cancer. Its expression is positively correlated with its cognate sense gene, FAM83A, and when overexpressed it increases FAM83A protein levels. This upregulation in turn promotes the phosphorylation of ERK1/2, thereby activating downstream signaling that enhances lung adenocarcinoma cell proliferation and invasion. In summary, FAM83A‐AS1 acts as an oncogenic lncRNA by upregulating FAM83A expression and stimulating cell signaling pathways essential for tumor progression (1).\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Rongxing Shi, Zichen Jiao, Ao Yu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long noncoding antisense RNA FAM83A-AS1 promotes lung cancer cell progression by increasing FAM83A."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.28336"}], "href": "https://doi.org/10.1002/jcb.28336"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30659636"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30659636"}]}]}]}