BAX Gene

Name	BCL2-associated X protein
Description	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n BAX is a quintessential proapoptotic member of the BCL‑2 family that functions as a molecular switch in the intrinsic mitochondrial apoptotic pathway. In nonstressed cells, BAX remains inert in the cytosol, but upon encountering diverse stress signals—often relayed by BH3‑only proteins such as Puma and BIM—it undergoes allosteric conformational changes that expose membrane‐targeting domains, triggering its translocation to the mitochondrial outer membrane."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": " Once at the mitochondria, BAX inserts into the membrane and oligomerizes into ring‐like structures that drive mitochondrial outer membrane permeabilization (MOMP) and the release of apoptogenic factors such as cytochrome c."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "6"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Diverse upstream signaling pathways—including p53 activation, endoplasmic reticulum stress, and MAPK responses—converge upon BAX to fine‑tune its activation in multiple cell types such as hepatocytes, neurons, and immune cells."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "10"}]}, {"type": "t", "text": " In these contexts, proper execution of apoptosis is critical—for instance, failure to activate BAX has been linked to chemoresistance"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": ", while excessive or aberrant BAX activity can lead to mitochondrial DNA leakage that activates innate immune pathways in acute kidney injury"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": "and contribute to plaque destabilization during atherosclerosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Moreover, the efficacy of BAX activation is influenced by mitochondrial parameters and cellular context. Sufficient mitochondrial size is required to stabilize BAX–membrane interactions"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": ", and in T cells, the absence of BAX (along with its homolog BAK) impairs receptor‐mediated calcium signaling and energy metabolism."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": " Likewise, conditions of oxidative stress, such as those induced by atmospheric oxygen in mesenchymal stem cells, lead to upregulation of BAX and subsequent apoptotic death."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "17"}]}, {"type": "t", "text": " \n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Collectively, these studies underscore the central role of BAX as an integrative sensor of diverse pro‑apoptotic signals. By undergoing regulated conformational activation and oligomerization at the mitochondrial outer membrane, BAX not only commits cells to apoptosis but also intersects with broader cellular processes—from immune cell function to responses against chemotherapeutic stress—highlighting its significance in both physiological homeostasis and disease."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}, {"type": "fg_f", "ref": "4"}, {"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bin Guo, Dayong Zhai, Edelmira Cabezas, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Humanin peptide suppresses apoptosis by interfering with Bax activation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature01627"}], "href": "https://doi.org/10.1038/nature01627"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12732850"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12732850"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Kristopher A Sarosiek, Xiaoke Chi, John A Bachman, et al. "}, {"type": "b", "children": [{"type": "t", "text": "BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2013.08.048"}], "href": "https://doi.org/10.1016/j.molcel.2013.08.048"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24074954"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24074954"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Diana Steckley, Meera Karajgikar, Lianne B Dale, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.3400-07.2007"}], "href": "https://doi.org/10.1523/JNEUROSCI.3400-07.2007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18032672"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18032672"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Evripidis Gavathiotis, Denis E Reyna, Marguerite L Davis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "BH3-triggered structural reorganization drives the activation of proapoptotic BAX."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2010.10.019"}], "href": "https://doi.org/10.1016/j.molcel.2010.10.019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21070973"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21070973"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Lena Große, Christian A Wurm, Christian Brüser, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO J (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.15252/embj.201592789"}], "href": "https://doi.org/10.15252/embj.201592789"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26783364"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26783364"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Loren D Walensky, Evripidis Gavathiotis "}, {"type": "b", "children": [{"type": "t", "text": "BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Trends Biochem Sci (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.tibs.2011.08.009"}], "href": "https://doi.org/10.1016/j.tibs.2011.08.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21978892"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21978892"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Yuko Akazawa, Sophie Cazanave, Justin L Mott, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Hepatol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jhep.2010.01.003"}], "href": "https://doi.org/10.1016/j.jhep.2010.01.003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20206402"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20206402"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Ying Meng, Chang-Hui Yu, Wei Li, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.146738"}], "href": "https://doi.org/10.1074/jbc.M110.146738"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21047780"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21047780"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "G S Choudhary, S Al-Harbi, S Mazumder, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2019.09.050"}], "href": "https://doi.org/10.1016/j.celrep.2019.09.050"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31665638"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31665638"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Hiroto Tsukano, Tomomi Gotoh, Motoyoshi Endo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/ATVBAHA.110.206094"}], "href": "https://doi.org/10.1161/ATVBAHA.110.206094"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20651282"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20651282"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Thibaud T Renault, Konstantinos V Floros, Rana Elkholi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2014.10.028"}], "href": "https://doi.org/10.1016/j.molcel.2014.10.028"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25482509"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25482509"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Russell G Jones, Thi Bui, Carl White, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Immunity (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.immuni.2007.05.023"}], "href": "https://doi.org/10.1016/j.immuni.2007.05.023"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17692540"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17692540"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "C Wang, R J Youle "}, {"type": "b", "children": [{"type": "t", "text": "Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncogene (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/onc.2011.497"}], "href": "https://doi.org/10.1038/onc.2011.497"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22056880"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22056880"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Siddaraju V Boregowda, Veena Krishnappa, Jeremy W Chambers, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Atmospheric oxygen inhibits growth and differentiation of marrow-derived mouse mesenchymal stem cells via a p53-dependent mechanism: implications for long-term culture expansion."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/stem.1069"}], "href": "https://doi.org/10.1002/stem.1069"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22367737"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22367737"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Emily K Pugach, Phillip A Richmond, Joseph G Azofeifa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Cell Cardiol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yjmcc.2015.06.019"}], "href": "https://doi.org/10.1016/j.yjmcc.2015.06.019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26141530"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26141530"}]}]}]}
Synonyms	BCL2L4
Proteins	BAX_HUMAN
NCBI Gene ID	581
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

BAX has 23,489 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 136 datasets.

Click the + buttons to view associations for BAX from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

BAX Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of BAX gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of BAX gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of BAX gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of BAX gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of BAX gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of BAX gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	Biocarta Pathways	pathways involving BAX protein from the Biocarta Pathways dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of BAX gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of BAX gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of BAX gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of BAX gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of BAX gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of BAX gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with BAX gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with BAX protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with BAX gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of BAX gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of BAX gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of BAX gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of BAX gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing BAX protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing BAX protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with BAX protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with BAX protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing BAX protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of BAX gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with BAX gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with BAX gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with BAX gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of BAX protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by BAX gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DEPOD Substrates of Phosphatases	phosphatases that dephosphorylate BAX protein from the curated DEPOD Substrates of Phosphatases dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving BAX gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with BAX gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with BAX gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with BAX gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with BAX gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with BAX gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at BAX gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of BAX gene from the ENCODE Transcription Factor Binding Site Profiles dataset.