| Name | bublin coiled coil protein |
| Description | Enables molecular adaptor activity. Involved in intermediate filament bundle assembly. Located in cell junction; polymeric cytoskeletal fiber; and subapical part of cell. [provided by Alliance of Genome Resources, Mar 2025] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Despite the diverse themes explored in these studies—from cell‐cycle regulation in neural and non‐neural tissues (1), through advanced methodologies to extract and interpret gene expression profiles in Alzheimer’s disease, heterogeneous cancers, and other complex conditions (2, 3, 6), to investigations of platelet transcriptomics (4), polysaccharide bioactivity (5), heat‐resistant proteins (7), synovitis in osteoarthritis (8) and key gene identification in ovarian cancer (9)—none of the abstracts provide data or discussion regarding a gene or protein denoted “BBLN.” In other words, while these studies offer insight into multiple molecules and biological processes, the function of BBLN is not addressed in any of them.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Consequently, based on the available literature provided here, no specific functional characterization for BBLN can be inferred. Further investigation would be needed to determine the role of BBLN in biological systems."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "9"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jianfeng Xiao, Satya R Vemula, Yi Xue, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Motor phenotypes and molecular networks associated with germline deficiency of Ciz1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Neurol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.expneurol.2016.05.006"}], "href": "https://doi.org/10.1016/j.expneurol.2016.05.006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27163549"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27163549"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Wei Kong, Xiaoyang Mou, Qingzhong Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Independent component analysis of Alzheimer's DNA microarray gene expression data."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Neurodegener (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1750-1326-4-5"}], "href": "https://doi.org/10.1186/1750-1326-4-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19173745"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19173745"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Wataru Fujibuchi, Tsuyoshi Kato "}, {"type": "b", "children": [{"type": "t", "text": "Classification of heterogeneous microarray data by maximum entropy kernel."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Bioinformatics (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2105-8-267"}], "href": "https://doi.org/10.1186/1471-2105-8-267"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17651507"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17651507"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "David C Calverley, Tzu L Phang, Qamrul G Choudhury, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Significant downregulation of platelet gene expression in metastatic lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Transl Sci (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1752-8062.2010.00226.x"}], "href": "https://doi.org/10.1111/j.1752-8062.2010.00226.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21500395"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21500395"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "S Abakuks, A M Deters "}, {"type": "b", "children": [{"type": "t", "text": "Polysaccharides of St. John's Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Adv Pharmacol Sci (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2012/304317"}], "href": "https://doi.org/10.1155/2012/304317"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22848211"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22848211"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Jin Zhou, Xiaoyu Wu, Gang Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Prediction of radiosensitive patients with gastric cancer by developing gene signature."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Oncol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ijo.2017.4107"}], "href": "https://doi.org/10.3892/ijo.2017.4107"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28902346"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28902346"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Kotaro Tsuboyama, Tatsuya Osaki, Eriko Matsuura-Suzuki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Biol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pbio.3000632"}], "href": "https://doi.org/10.1371/journal.pbio.3000632"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32163402"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32163402"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Hui Huang, Jiaxuan Zheng, Ningjiang Shen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of pathways and genes associated with synovitis in osteoarthritis using bioinformatics analyses."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-018-28280-6"}], "href": "https://doi.org/10.1038/s41598-018-28280-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29968759"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29968759"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "J Wang, C Chen, H-F Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Investigating key genes associated with ovarian cancer by integrating affinity propagation clustering and mutual information network analysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Eur Rev Med Pharmacol Sci (2016)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27383302"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27383302"}]}]}]}
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| NCBI Gene ID | 79095 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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BBLN has 1,987 functional associations with biological entities spanning 6 categories (chemical, functional term, phrase or reference, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 22 datasets.
Click the + buttons to view associations for BBLN from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of BBLN gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Carcinogenome Chemical Perturbation Carcinogenicity Signatures | small molecule perturbations changing expression of BBLN gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset. | |
| CellMarker Gene-Cell Type Associations | cell types associated with BBLN gene from the CellMarker Gene-Cell Type Associations dataset. | |
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of BBLN gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| GO Biological Process Annotations 2025 | biological processes involving BBLN gene from the curated GO Biological Process Annotations2025 dataset. | |
| GO Cellular Component Annotations 2025 | cellular components containing BBLN protein from the curated GO Cellular Component Annotations 2025 dataset. | |
| GTEx eQTL 2025 | SNPs regulating expression of BBLN gene from the GTEx eQTL 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of BBLN gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| GTEx Tissue-Specific Aging Signatures | tissue samples with high or low expression of BBLN gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset. | |
| GWAS Catalog SNP-Phenotype Associations 2025 | phenotypes associated with BBLN gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. | |
| HuBMAP ASCT+B Annotations | cell types associated with BBLN gene from the HuBMAP ASCT+B dataset. | |
| HuBMAP ASCT+B Augmented with RNA-seq Coexpression | cell types associated with BBLN gene from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of BBLN gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of BBLN gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| LINCS L1000 CMAP Chemical Perturbation Consensus Signatures | small molecule perturbations changing expression of BBLN gene from the LINCS L1000 CMAP Chemical Perturbations Consensus Signatures dataset. | |
| Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of BBLN gene from the Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures dataset. | |
| Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of BBLN gene from the Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures dataset. | |
| Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures | gene perturbations changing expression of BBLN gene from the Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of BBLN gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of BBLN gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of BBLN gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Sci-Plex Drug Perturbation Signatures | drug perturbations changing expression of BBLN gene from the Sci-Plex Drug Perturbation Signatures dataset. | |
