BMPR2 Gene

HGNC Family	Receptor kinases
Name	bone morphogenetic protein receptor, type II (serine/threonine kinase)
Description	This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Bone morphogenetic protein receptor type II (BMPR2) is a transmembrane serine/threonine kinase that serves as a central mediator of bone morphogenetic protein (BMP) signaling in several tissues. In endothelial cells, BMPR2 forms part of a receptor complex that binds BMP ligands such as BMP9 and BMP7, triggering canonical SMAD1/5/8 phosphorylation and downstream gene regulation to inhibit proliferation, stimulate apoptosis, and maintain vascular quiescence—processes that are vital for angiogenesis and vascular integrity."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In the pulmonary vasculature, diminished BMPR2 expression or mutant BMPR2 causes a shift in cellular behavior that predisposes to pulmonary arterial hypertension (PAH); affected patients develop earlier onset disease with more severe hemodynamic compromise, a finding consistently observed in both human studies and animal models."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "3", "end_ref": "6"}]}, {"type": "t", "text": " Moreover, regulatory mechanisms—such as STAT3-mediated induction of the miR-17/92 cluster—further downregulate BMPR2 protein levels, thereby perpetuating the proproliferative, antiapoptotic state of pulmonary vascular cells."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": " Restoration of BMPR2 signaling, for example by administration of BMP9 or by using pharmacologic agents that overcome receptor dysfunction, improves endothelial function and reverses established PAH in preclinical models."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n Outside the pulmonary circulation, BMPR2 is implicated in other physiological processes. In prostate cancer stem-like cells, BMPR2 mediates BMP7 signaling through a p38-NDRG1 axis that induces cellular senescence and dormancy, thereby suppressing metastatic outgrowth."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "10"}]}, {"type": "t", "text": " In the liver, BMPR2 participates in hemojuvelin-dependent BMP signaling that modulates hepcidin expression and iron metabolism"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": ", while in ovarian granulosa cells BMPR2 functions as a key binding partner for ligands such as growth differentiation factor‑9 (GDF9) that regulate folliculogenesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "12"}]}, {"type": "t", "text": " Furthermore, studies in pulmonary artery smooth muscle cells suggest that when BMPR2 expression is impaired, alternate type II receptors (e.g. ActRIIa) may compensate for some BMP ligands but lead to an altered repertoire of type I receptor usage and signaling intensity."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": " Recent findings also indicate that BMPR2 loss in endothelial cells can promote endothelial‐to‐mesenchymal transition through upregulation of factors such as HMGA1."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n \n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, BMPR2 functions as a critical regulator of BMP ligand signaling that influences cell fate decisions—including proliferation, apoptosis, differentiation, and cellular plasticity—in diverse tissues. Its proper activity is essential for maintaining vascular homeostasis and other organ functions, whereas dysfunction or mutation of BMPR2 can predispose to severe diseases such as pulmonary arterial hypertension and contribute to pathological remodeling in various systems."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "14"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Laurent David, Christine Mallet, Sabine Mazerbourg, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2006-07-034124"}], "href": "https://doi.org/10.1182/blood-2006-07-034124"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17068149"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17068149"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Marion Scharpfenecker, Maarten van Dinther, Zhen Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.002949"}], "href": "https://doi.org/10.1242/jcs.002949"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17311849"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17311849"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Rajiv D Machado, Micheala A Aldred, Victoria James, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mutat (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/humu.20285"}], "href": "https://doi.org/10.1002/humu.20285"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16429395"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16429395"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Jonathan D W Evans, Barbara Girerd, David Montani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Lancet Respir Med (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/S2213-2600(15)00544-5"}], "href": "https://doi.org/10.1016/S2213-2600(15"}, {"type": "t", "text": "00544-5) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26795434"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26795434"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Benjamin Sztrymf, Florence Coulet, Barbara Girerd, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Respir Crit Care Med (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1164/rccm.200712-1807OC"}], "href": "https://doi.org/10.1164/rccm.200712-1807OC"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18356561"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18356561"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Kwon-Ho Hong, Young Jae Lee, Eunji Lee, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circulation (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCULATIONAHA.107.736801"}], "href": "https://doi.org/10.1161/CIRCULATIONAHA.107.736801"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18663089"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18663089"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Matthias Brock, Michelle Trenkmann, Renate E Gay, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCRESAHA.109.197491"}], "href": "https://doi.org/10.1161/CIRCRESAHA.109.197491"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19390056"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19390056"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Lu Long, Mark L Ormiston, Xudong Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm.3877"}], "href": "https://doi.org/10.1038/nm.3877"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26076038"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26076038"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "James West, Karen Fagan, Wolfgang Steudel, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Res (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/01.RES.0000126047.82846.20"}], "href": "https://doi.org/10.1161/01.RES.0000126047.82846.20"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15031260"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15031260"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Aya Kobayashi, Hiroshi Okuda, Fei Xing, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Med (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1084/jem.20110840"}], "href": "https://doi.org/10.1084/jem.20110840"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22124112"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22124112"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Yin Xia, Jodie L Babitt, Yisrael Sidis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Blood (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1182/blood-2007-09-111567"}], "href": "https://doi.org/10.1182/blood-2007-09-111567"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18326817"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18326817"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Ursula A Vitt, Sabine Mazerbourg, Cynthia Klein, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Reprod (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1095/biolreprod67.2.473"}], "href": "https://doi.org/10.1095/biolreprod67.2.473"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12135884"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12135884"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Paul B Yu, Hideyuki Beppu, Noriko Kawai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M502825200"}], "href": "https://doi.org/10.1074/jbc.M502825200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15883158"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15883158"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Rachel K Hopper, Jan-Renier A J Moonen, Isabel Diebold, et al. "}, {"type": "b", "children": [{"type": "t", "text": "In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circulation (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCULATIONAHA.115.020617"}], "href": "https://doi.org/10.1161/CIRCULATIONAHA.115.020617"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27045138"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27045138"}]}]}]}
Synonyms	BMPR-II, BMR2, BMPR3, BRK-3, POVD1, PPH1, T-ALK
Proteins	BMPR2_HUMAN
NCBI Gene ID	659
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

BMPR2 has 9,393 functional associations with biological entities spanning 9 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 135 datasets.

Click the + buttons to view associations for BMPR2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

BMPR2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by BMPR2 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of BMPR2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of BMPR2 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of BMPR2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of BMPR2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of BMPR2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	Biocarta Pathways	pathways involving BMPR2 protein from the Biocarta Pathways dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of BMPR2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of BMPR2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of BMPR2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of BMPR2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of BMPR2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with BMPR2 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with BMPR2 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with BMPR2 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of BMPR2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of BMPR2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of BMPR2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with BMPR2 gene from the curated ClinVar Gene-Phenotype Associations dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of BMPR2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing BMPR2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing BMPR2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing BMPR2 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with BMPR2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with BMPR2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with BMPR2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with BMPR2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with BMPR2 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with BMPR2 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of BMPR2 protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by BMPR2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DEPOD Substrates of Phosphatases	phosphatases that dephosphorylate BMPR2 protein from the curated DEPOD Substrates of Phosphatases dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores	diseases involving BMPR2 gene from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving BMPR2 gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with BMPR2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with BMPR2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with BMPR2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with BMPR2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with BMPR2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with BMPR2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.