| Name | chromosome 18 open reading frame 12 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent genome-wide association studies in a Han Chinese population have identified a novel locus near the gene C18orf12 that is significantly associated with human height."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Although the precise molecular function of C18orf12 remains to be fully characterized, its genome-wide significance in this study suggests that genetic variation in or near this gene may contribute to the biological regulation of stature. This finding highlights C18orf12 as a promising candidate for further research aimed at elucidating the pathways involved in growth and development.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yongchen Hao, Xuehui Liu, Xiangfeng Lu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-wide association study in Han Chinese identifies three novel loci for human height."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Genet (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00439-013-1280-9"}], "href": "https://doi.org/10.1007/s00439-013-1280-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23456168"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23456168"}]}]}]}
|
| Synonyms | C18orf12, HEIL1, HST2508 |
| Proteins | CR012_HUMAN |
| NCBI Gene ID | 84322 |
| API | |
| Download Associations | |
| Predicted Functions |
![]() |
| Co-expressed Genes |
![]() |
| Expression in Tissues and Cell Lines |
![]() |
C18ORF12 has 379 functional associations with biological entities spanning 4 categories (organism, chemical, functional term, phrase or reference, cell line, cell type or tissue) extracted from 9 datasets.
Click the + buttons to view associations for C18ORF12 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of C18ORF12 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of C18ORF12 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of C18ORF12 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of C18ORF12 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene Expression Profiles | cell lines with high or low expression of C18ORF12 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of C18ORF12 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of C18ORF12 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of C18ORF12 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain C18ORF12 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |