| Name | chromosome 18 open reading frame 15 |
| Description | Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n The study summarized in this abstract focused on identifying candidate genes for dyslexia susceptibility on chromosome 18 (PMID:."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Using a combination of linkage and association analyses in UK and US families, the researchers identified three genes—melanocortin 5 receptor (MC5R), dymeclin (DYM), and neural precursor cell expressed, developmentally down-regulated 4-like (NEDD4L)—as showing consistent association with dyslexia. These genes emerged as attractive candidates given both the statistical associations and supporting biological evidence; however, additional replication and functional studies were recommended.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n It is important to note that this abstract does not mention or provide any experimental or functional insights regarding the gene C18orf15. Therefore, based on the information from this publication alone, there is no summary of the function of C18orf15.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Thomas S Scerri, Silvia Paracchini, Andrew Morris, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of candidate genes for dyslexia susceptibility on chromosome 18."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0013712"}], "href": "https://doi.org/10.1371/journal.pone.0013712"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21060895"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21060895"}]}]}]}
|
| Synonyms | C18orf15, HST3231 |
| Proteins | CR015_HUMAN |
| NCBI Gene ID | 147276 |
| API | |
| Download Associations | |
| Predicted Functions |
![]() |
| Co-expressed Genes |
![]() |
| Expression in Tissues and Cell Lines |
![]() |
C18ORF15 has 232 functional associations with biological entities spanning 7 categories (molecular profile, organism, disease, phenotype or trait, chemical, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for C18ORF15 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of C18ORF15 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of C18ORF15 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of C18ORF15 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of C18ORF15 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of C18ORF15 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of C18ORF15 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of C18ORF15 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of C18ORF15 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of C18ORF15 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of C18ORF15 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain C18ORF15 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |