CIAPIN1 Gene

Name	cytokine induced apoptosis inhibitor 1
Description	CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Cytokine‐induced apoptosis inhibitor 1 (CIAPIN1), also known as anamorsin, is a multifunctional protein that plays essential roles in both normal cellular physiology and cancer. In non‐malignant settings, CIAPIN1 is critical for cytosolic iron–sulfur (Fe/S) protein biogenesis, functioning in electron transfer processes that support the activity of Fe/S‐dependent enzymes important for metabolism, DNA maintenance, and iron homeostasis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": " Its role in hematopoiesis and embryogenesis is equally critical; studies in mice have demonstrated that CIAPIN1 is indispensable for definitive hematopoiesis, with loss of function resulting in embryonic lethality and profound defects in blood cell development."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In the context of cancer, CIAPIN1 exhibits complex and context‐dependent functions. In several malignancies such as gastric cancer and leukemia, elevated CIAPIN1 expression has been associated with the development of multidrug resistance through the upregulation of drug efflux transporters (e.g., MDR1 and MRP1) and anti‐apoptotic regulators, thereby protecting tumor cells from chemotherapeutic‐induced apoptosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": " Conversely, in other tumor types including hepatocellular, gastric, and colorectal cancers, reduced CIAPIN1 expression correlates with enhanced cell proliferation, deregulated cell cycle progression, and poorer patient prognosis, suggesting that CIAPIN1 can also function as a tumor suppressor."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "8", "end_ref": "10"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Moreover, CIAPIN1 has been implicated in the suppression of metastatic functions. In breast and lung cancer models, its overexpression inhibits migration, invasion, and the expression of matrix metalloproteinases by modulating signaling pathways involving ERK1/2 and the Na+/H+ exchanger NHE1, thereby reducing the epithelial–mesenchymal transition and metastatic potential."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "11"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n The diverse functions of CIAPIN1 are further underscored by its complex subcellular distribution; it localizes both to the cytoplasm and the nucleus – with notable accumulation in the nucleolus – which likely enables its participation in multiple regulatory pathways."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "13"}]}, {"type": "t", "text": " In ovarian cancer, for instance, nuclear expression of CIAPIN1 correlates with tumor dedifferentiation and serves as an independent unfavorable prognostic marker."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, CIAPIN1/anamorsin functions as a pivotal mediator of cellular survival, differentiation, and iron metabolism under normal physiological conditions, while its dysregulation contributes to chemoresistance, altered proliferation, and metastatic behavior in various cancers.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Lucia Banci, Ivano Bertini, Simone Ciofi-Baffoni, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Chem Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.chembiol.2011.03.015"}], "href": "https://doi.org/10.1016/j.chembiol.2011.03.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21700214"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21700214"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Lucia Banci, Francesca Camponeschi, Simone Ciofi-Baffoni, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Am Chem Soc (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1021/jacs.5b10592"}], "href": "https://doi.org/10.1021/jacs.5b10592"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26613676"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26613676"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Lucia Banci, Simone Ciofi-Baffoni, Karolina Gajda, et al. "}, {"type": "b", "children": [{"type": "t", "text": "N-terminal domains mediate [2Fe-2S] cluster transfer from glutaredoxin-3 to anamorsin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Chem Biol (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nchembio.1892"}], "href": "https://doi.org/10.1038/nchembio.1892"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26302480"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26302480"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Hirohiko Shibayama, Emi Takai, Itaru Matsumura, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Med (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1084/jem.20031858"}], "href": "https://doi.org/10.1084/jem.20031858"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14970183"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14970183"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Yuri Saito, Hirohiko Shibayama, Hirokazu Tanaka, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PICOT is a molecule which binds to anamorsin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2011.04.033"}], "href": "https://doi.org/10.1016/j.bbrc.2011.04.033"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21513700"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21513700"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Zhiming Hao, Xiaohua Li, Taidong Qiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Biol Ther (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/cbt.5.3.2381"}], "href": "https://doi.org/10.4161/cbt.5.3.2381"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16410721"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16410721"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Xiaohua Li, Liu Hong, Yunping Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Cell Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1139/o07-141"}], "href": "https://doi.org/10.1139/o07-141"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18059532"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18059532"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Xiaohua Li, Yanglin Pan, Rui Fan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Carcinogenesis (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/carcin/bgn052"}], "href": "https://doi.org/10.1093/carcin/bgn052"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18299278"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18299278"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Xiaohua Li, Zhiming Hao, Rui Fan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CIAPIN1 inhibits gastric cancer cell proliferation and cell cycle progression by downregulating CyclinD1 and upregulating P27."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Biol Ther (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/cbt.6.10.4684"}], "href": "https://doi.org/10.4161/cbt.6.10.4684"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18293492"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18293492"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Hai Shi, Yi Zhou, Heliang Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of CIAPIN1 in human colorectal cancer and its correlation with prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Cancer (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2407-10-477"}], "href": "https://doi.org/10.1186/1471-2407-10-477"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20815902"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20815902"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Jian Wang, Hua Xu, Qi Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CIAPIN1 targets Na⁺/H⁺ exchanger 1 to mediate MDA-MB-231 cells' metastasis through regulation of MMPs via ERK1/2 signaling pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2015.02.012"}], "href": "https://doi.org/10.1016/j.yexcr.2015.02.012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25724898"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25724898"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Jian Wang, Ying Zhou, Li Ma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells' Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oxid Med Cell Longev (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2019/1970818"}], "href": "https://doi.org/10.1155/2019/1970818"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31093311"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31093311"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Zhiming Hao, Xiaohua Li, Taidong Qiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Subcellular localization of CIAPIN1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Histochem Cytochem (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1369/jhc.6A6960.2006"}], "href": "https://doi.org/10.1369/jhc.6A6960.2006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16957168"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16957168"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "X Chen, X Li, J Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Overexpression of CIAPIN1 inhibited pancreatic cancer cell proliferation and was associated with good prognosis in pancreatic cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Gene Ther (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/cgt.2012.28"}], "href": "https://doi.org/10.1038/cgt.2012.28"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22677939"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22677939"}]}]}]}
Synonyms	ANAMORSIN, DRE2, PRO0915, CIAE2
Proteins	CPIN1_HUMAN
NCBI Gene ID	57019
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

CIAPIN1 has 6,765 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 119 datasets.

Click the + buttons to view associations for CIAPIN1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

CIAPIN1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CIAPIN1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of CIAPIN1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of CIAPIN1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of CIAPIN1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of CIAPIN1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of CIAPIN1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of CIAPIN1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of CIAPIN1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of CIAPIN1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of CIAPIN1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of CIAPIN1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with CIAPIN1 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with CIAPIN1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CIAPIN1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of CIAPIN1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of CIAPIN1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of CIAPIN1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing CIAPIN1 protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of CIAPIN1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing CIAPIN1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing CIAPIN1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing CIAPIN1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with CIAPIN1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with CIAPIN1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of CIAPIN1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with CIAPIN1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with CIAPIN1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with CIAPIN1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with CIAPIN1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with CIAPIN1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with CIAPIN1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with CIAPIN1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at CIAPIN1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CIAPIN1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of CIAPIN1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing CIAPIN1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of CIAPIN1 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with CIAPIN1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing CIAPIN1 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of CIAPIN1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.