{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In a recent study exploring the molecular underpinnings of ovarian endometriosis, CKMT2‐AS1 emerged as one of the top hub long noncoding RNAs (lncRNAs) within a competing endogenous RNA (ceRNA) network. In this network, CKMT2‐AS1 is linked to mRNAs that are functionally enriched in processes such as the positive regulation of phagocytosis, activation of myeloid leukocytes, and tissue remodeling—pathways that are thought to contribute to the pathogenesis and development of endometriosis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In a separate study investigating MYC-driven cell proliferation in lymphoid cancer cell lines, a broad panel of lncRNAs was identified as essential for cell growth. Although CKMT2‐AS1 was not specifically highlighted in that context, the study underscores the potential significance of lncRNAs in regulating cellular proliferation and other biological processes, thereby reinforcing the idea that dysregulated lncRNAs such as CKMT2‐AS1 may play critical regulatory roles in disease."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Chenglei Gu, Yuanguang Meng, Qingqing Meng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Exploring the Potential Key IncRNAs with Endometriosis by Construction of a ceRNA Network."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Gen Med (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2147/IJGM.S321648"}], "href": "https://doi.org/10.2147/IJGM.S321648"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34385836"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34385836"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Philipp Raffeiner, Jonathan R Hart, Daniel García-Caballero, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1921786117"}], "href": "https://doi.org/10.1073/pnas.1921786117"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32156728"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32156728"}]}]}]}