CT45A2 Gene

Name	cancer/testis antigen family 45, member A2
Description	This gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer/testis (CT) family of antigens, and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers. [provided by RefSeq, Apr 2014]
Synonyms	CT45A8, CT45-2, CT45.2
Proteins	CT452_HUMAN
NCBI Gene ID	728911
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

CT45A2 has 380 functional associations with biological entities spanning 6 categories (molecular profile, disease, phenotype or trait, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 16 datasets.

Click the + buttons to view associations for CT45A2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome

CT45A2 Gene

Functional Associations

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Funding

	Dataset	Summary
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of CT45A2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of CT45A2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	DISEASES Text-mining Gene-Disease Assocation Evidence Scores	diseases co-occuring with CT45A2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of CT45A2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of CT45A2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with CT45A2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing CT45A2 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of CT45A2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of CT45A2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	HPA Cell Line Gene Expression Profiles	cell lines with high or low expression of CT45A2 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of CT45A2 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of CT45A2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	TargetScan Predicted Nonconserved microRNA Targets	microRNAs regulating expression of CT45A2 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of CT45A2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with CT45A2 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
	TRANSFAC Predicted Transcription Factor Targets	transcription factors regulating expression of CT45A2 gene predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.