| HGNC Family | Cytochrome P450s (CYP) |
| Name | cytochrome P450, family 2, subfamily A |
| Description | The cytochrome P450 superfamily of enzymes are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2 gene cluster on chromosome 19q13.2 includes several genes and pseudogenes from the CYP2A, CYP2B, and CYP2F subfamilies. [provided by RefSeq, Jul 2008] |
| Synonyms | P450C2, CYP2 |
| NCBI Gene ID | 1546 |
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| Predicted Functions |
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| Expression in Tissues and Cell Lines |
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CYP2A has 20 functional associations with biological entities spanning 3 categories (chemical, disease, phenotype or trait, functional term, phrase or reference) extracted from 5 datasets.
Click the + buttons to view associations for CYP2A from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CTD Gene-Chemical Interactions | chemicals interacting with CYP2A gene/protein from the curated CTD Gene-Chemical Interactions dataset. | |
| GAD Gene-Disease Associations | diseases associated with CYP2A gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. | |
| GAD High Level Gene-Disease Associations | diseases associated with CYP2A gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset. | |
| GeneRIF Biological Term Annotations | biological terms co-occuring with CYP2A gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
| HuGE Navigator Gene-Phenotype Associations | phenotypes associated with CYP2A gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. | |
